ライフサイエンスコーパス: self-avoidance

1 impairs dendritic arborization and dendrite self-avoidance.

2 important for neuronal self-recognition and self-avoidance.

3 evolution of a common molecular strategy for self-avoidance.

4 pulsion between processes, thereby promoting self-avoidance.

5 functions in an analogous fashion to promote self-avoidance.

6 rodevelopmental processes, including neurite self-avoidance.

7 drite and dendrite-substrate interactions in self-avoidance.

8 s) generate a repulsive signal that leads to self-avoidance.

9 ary isoforms within the same neuron restored self-avoidance.

10 icating a role for substrate interactions in self-avoidance.

11 cdhg proteins with a single isoform restores self-avoidance.

12 e same cell provides the molecular basis for self-avoidance.

13 evere axonal arborization defect and loss of self-avoidance.

14 distinguish between self and non-self during self-avoidance.

15 ity provides the molecular basis for neurite self-avoidance.

16 ies in Dscam(-/-) mice, suggesting a role in self-avoidance.

17 crine cell bodies, also indicating a role in self-avoidance.

18 ants was sufficient to significantly restore self-avoidance.

19 ontact with one another, a behavior known as self-avoidance.

20 c arbour, increased branching and failure of self-avoidance.

21 y and tiling pattern reminiscent of neuronal self-avoidance.

22 /non-self-discrimination underlying neuronal self-avoidance.

23 zed over multiple timescales and governed by self-avoidance.

24 ss evolution and forms the basis of neuronal self-avoidance(1-4).

25 in self-recognition and repulsion leading to self-avoidance [3-11].

26 overlap is prevented by a contact-dependent self-avoidance, a mechanism that is also employed by sen

27 Self-avoidance, a process preventing interactions of axo

28 n usually develop nonoverlapping patterns by self-avoidance, a process requiring contact-dependent re

29 ring homotypic neurons, indicating a role in self-avoidance among cells of a given type, a disruption

30 nition and non-self-discrimination to direct self-avoidance among vertebrate neurons.

31 ers a local repulsive mechanism required for self-avoidance and demonstrates the molecular complexity

32 read role in neural circuit assembly through self-avoidance and is incompatible with models in which

33 lustered protocadherins (Pcdhs) in dendritic self-avoidance and self/non-self discrimination.

34 form-specific interactions, and mediate both self-avoidance and self/non-self discrimination.

35 cdhs mediate homophilic adhesion and lead to self-avoidance and tiling by giving neurons specific ide

36 rons still exhibited tiling, suggesting that self-avoidance and tiling differ in their recognition an

37 mutually exclusive dendritic domains through self-avoidance and tiling mechanisms.

38 tudies have uncovered the molecular basis of self-avoidance and tiling, two fundamental principles re

39 mouse indicate that DSCAM functions in both self-avoidance and tiling.

40 ereby facilitates contact-mediated dendritic self-avoidance and tiling.

41 ore, DSCAM and DSCAML1 function similarly in self-avoidance, and are not essential for synaptic speci

42 g control of axon growth, branching, neurite self-avoidance, and neuronal cell death.

43 They maintained unique territories though self-avoidance, and NG2(+) cell loss though death, diffe

44 hermalized elastic membranes without distant self-avoidance are believed to undergo a crumpling trans

45 evelopment of this organization by promoting self-avoidance at the level of cell types, promoting nor

46 Self-avoidance behavior has been shown to depend on cell

47 rborization suggested that contact-dependent self-avoidance between dendrite branches prevents self-c

48 idence suggests that they play a key role in self-avoidance between sister branches from neurons, whi

49 in mutant neurons, suggesting that dendritic self-avoidance, but not heteroneuronal tiling, may depen

50 Our results suggest that Dscam1-mediated self-avoidance counters extrinsic signals that are requi

51 misregulation of DMA-1 also causes dendritic self-avoidance defects.

52 ic adhesion, as well as self-recognition and self-avoidance, depending on the neuron type, brain regi

53 luding axon guidance, synaptic adhesion, and self-avoidance, depending on the species, cell type, and

54 hat the long-term superdiffusion arises from self-avoidance determined by cell size, highlighting the

55 eceptor isoforms on sister dendrites ensures self-avoidance even when only a single isoform is expres

56 g gaps and overlaps within the arborization, self-avoidance facilitates complete coverage of a neuron

57 demonstrates the cellular basis for dendrite self-avoidance following protocadherin-mediated self-rec

58 dicate that mouse DSCAM mediates isoneuronal self-avoidance for arborization and heteroneuronal self-

59 n often lead to repulsion, a process termed "self-avoidance." Here we demonstrate that dendrite self-

60 Dscam1 promotes self-avoidance in dendrites, axons, and prospective post

61 voidance." Here we demonstrate that dendrite self-avoidance in Drosophila da sensory neurons requires

62 ny neurons are patterned by a process called self-avoidance, in which branches arising from a single

63 axonal arbors of many neuronal types exhibit self-avoidance, in which branches repel each other.

64 differentiation, thermal regulation, neuron self-avoidance, infrared sensing, the Warburg effect, ma

65 Remarkably, some neurons that display self-avoidance interact freely with other neurons of the

66 SACs form autapses when self-avoidance is disrupted and fail to form connections

67 In Drosophila, self-avoidance is mediated by a large family of cell rec

68 This intrinsic self-avoidance mechanism ensures unambiguous processing

69 n Molecule (Dscam) is required for dendritic self-avoidance of all four classes of Drosophila dendrit

70 ted molecule Slit2 and its receptor Robo2 in self-avoidance of cerebellar Purkinje cells (PCs).

71 ouse gamma-subcluster (Pcdhg genes) disrupts self-avoidance of dendrites in retinal starburst amacrin

72 borizing their processes, which requires the self-avoidance of neurites from an individual cell, and

73 ance protein UNC-6 (Netrin), is required for self-avoidance of sister dendrites from the PVD nocicept

74 s raise a new set of questions: How does the self-avoidance of synaptic sites along an individual den

75 These isoforms failed to support self-avoidance or did so poorly.

76 both generates replay sequences and produces self-avoidance over the observed timescales.

77 Self-avoidance promotes complete territory coverage and

78 Self-avoidance refers to the tendency of branches from t

79 of growth, territory formation, tiling, and self-avoidance requires a quantitative comparison in con

80 Thus, self-avoidance, self/non-self discrimination, and synaps

81 ice shows that they are involved in dendrite self-avoidance, synapse development, dendritic arborizat

82 lecules, have a pivotal role in the neuronal self-avoidance that is required for mammalian brain deve

83 orm-specific homophilic binding and regulate self-avoidance, the tendency of neurites from the same c

84 Self-avoidance, the tendency of neurites of the same cel

85 Although any isoform can promote self-avoidance, thousands are necessary to ensure that n

86 ambling algorithm combined with a variety of self-avoidance thresholds to approximately model helix-c

87 r have functions including cell identity and self-avoidance through repulsion in Drosophila, differen

88 In Drosophila, Dscam1 mediates self-avoidance, whereas Dscam2 mediates tiling.

89 eural circuit assembly, via a process called self-avoidance, whether recognition specificity is essen

90 We conclude that, in contrast to neurite self-avoidance, which requires single-cell identity medi

91 voidance for arborization and heteroneuronal self-avoidance within specific cell types to prevent fas

92 dendritic arborization and reduced dendritic self-avoidance within the OPL.