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1 ability began their evolutionary path toward self-replication.
2  that are capable of complex behaviors, like self-replication.
3 n that is capable of complex behaviors, like self-replication.
4 eaking and chiral amplification in molecular self-replication.
5 A components alone can achieve autocatalytic self-replication.
6 hmic assembly, ultrasensitive detection, and self-replication.
7 , producing more compartments with increased self-replication.
8 ess of their biological role, are capable of self-replication.
9 emonstrated how this system can give rise to self-replication.
10                           Evolution requires self-replication.
11 plex beyond its CAC, leading to the onset of self-replication.
12 mal scheduling naturally emerges in cellular self-replication.
13 es), an important stepping stone towards RNA self-replication.
14 e sequences have the property of spontaneous self-replication.
15  their own census, likely through infrequent self-replication.
16 pic properties and are capable of continuous self-replication.
17 eriodic behavior with fundamental aspects of self-replication.
18 etic restriction and capacity for autonomous self-replication.
19 ing on nucleic acid polymers, allowing their self-replication.
20 ing of complex cellular behaviors, including self-replication.
21 nitial darwinian selection was for molecular self-replication.
22  independent of any genomic functions beyond self-replication.
23 s increased sensitivity, responsiveness, and self-replication.
24 exponential growth of ribozymes that undergo self-replication.
25 cently there were few examples of artificial self-replication.
26  can lead to increased responsiveness and to self-replication.
27 the smallest known microorganisms capable of self-replication.
28 ate would not have led to the termination of self-replication.
29 itectures, opening the door to incorporating self-replication, a hallmark of life, into biomimetic DN
30 talyze a critical reaction for prebiotic RNA self-replication according to the RNA world hypothesis.
31     The latter derived from partial ribozyme self-replication alongside generation of new RNA sequenc
32 ors with the high specificity, low cost, and self-replication and -repair of biocatalysts.
33 etabolites and processing units required for self-replication and additionally requiring that these p
34 e type of molecule was supposedly capable of self-replication and chemical catalysis.
35 e origin of life because they are sources of self-replication and compartmentalization.
36                                              Self-replication and evolution under selective pressure
37                                              Self-replication and exponential growth are essential to
38                                              Self-replication and exponential growth are ubiquitous i
39                                   Artificial self-replication and exponential growth holds the promis
40                                              Self-replication and exponential growth of autonomous mo
41                         The highly efficient self-replication and exponential growth of DNA origami d
42 mplification of aggregate mass and underlies self-replication and generation of toxic oligomers assoc
43 gence of an informational polymer capable of self-replication and its compartmentalization within pro
44 re the cellular regulation of conformational self-replication and its phenotypic effects, we analyzed
45 lls must select between alternative fates of self-replication and lineage commitment during continuou
46                             Examples include self-replication and molecular machines.
47 turational lineage stages and yet capable of self-replication and multipotent differentiation, being
48       Our findings establish the ubiquity of self-replication and point to its potential importance a
49  prebiotic synthesis to the emergence of RNA self-replication and precellular Darwinian evolution.
50 ny of the putative processes associated with self-replication and self-reproduction.
51                         Given that molecular self-replication and the capacity for selection are nece
52 mer extension dictates potential pathways to self-replication and, eventually, ribozymes.
53 inimum with blood cells, have a low level of self-replication, and depend on CSF-1.
54 tributed over its surface, and the rules for self-replication are encoded into the specificity and st
55 otic recombination clones point to JO neuron self-replication as a likely source of neuronal plastici
56 icated that the new beta-cells were not from self-replication but arose through differentiation of po
57                       Conditions under which self-replication can be significantly more effective und
58                      Using compartmentalized self-replication (CSR), we evolved a version of Pyrococc
59 ample in kinetic selection during catalysis, self-replication, dissipative self-assembly and syntheti
60                                      Optimal self-replication does not require constant energy expend
61 ivo favors differentiation at the expense of self-replication, eventually resulting in a complete los
62                                              Self-replication has also been implemented with syntheti
63                                              Self-replication has been demonstrated in synthetic chem
64 e origin of life, the feasibility of peptide self-replication has not been established experimentally
65 g the smallest and simplest cells capable of self-replication, has a distinct cellular polarity chara
66                      Mechanisms of molecular self-replication have the potential to shed light on the
67  persistent when released from cells with no self-replication in graywater.
68        An exciting next step would be to use self-replication in materials fabrication, which require
69 his work connects the domains of folding and self-replication in synthetic systems through dissipativ
70 ns of our experiments for the possibility of self-replication in the 3'-NP-DNA and RNA systems.
71  despite the central importance of molecular self-replication in the origin of life, the feasibility
72 thesis of (short) oligonucleotide sequences, self-replication in the present systems start from units
73                                    Bacterial self-replication is a complex process composed of many d
74                                              Self-replication is a fundamental concept.
75                                              Self-replication is a remarkable phenomenon in nature th
76                                              Self-replication is accompanied by self-assembly, sponta
77                                              Self-replication is an essential attribute of life but t
78  The emergence of an RNA catalyst capable of self-replication is considered a key transition in the o
79 The emergence of an RNA replicase capable of self-replication is considered an important stage in the
80 vity are compromised to the extent that full self-replication is inefficient.
81                            Non-enzymatic RNA self-replication is integral to the emergence of the 'RN
82 level of mechanistic insights into aggregate self-replication is key in the rational design of potent
83 ed to fulfill a structural role, the rate of self-replication is too low to be significant on the bio
84 cence, which leads to a diminished beta-cell self-replication, massive depletion of the pancreatic is
85 w, suggesting that there may be undiscovered self-replication mechanisms possible in much simpler sys
86 ided the use of enzymes to get a hint of how self-replication might have evolved in a prebiotic world
87 reatitis was best characterized by an acinar self-replication model because no evidence of a cellular
88 catalytic strategy we also demonstrate rapid self-replication of a hybrid wireframe triangle containi
89 nd microorganisms, and could have driven the self-replication of a protobiont.
90              Here we describe the autonomous self-replication of a reconfigurable string of parts fro
91                                 We find that self-replication of A[Formula: see text] fibrils occurs
92                    In the context of AD, the self-replication of aggregates of the AB42 peptide by se
93                                              Self-replication of amyloid fibrils via secondary nuclea
94                                              Self-replication of bioorganic molecules and oil microdr
95 containing synthetic vertices as well as the self-replication of circular DNA.
96 er liver injury, regeneration occurs through self-replication of hepatocytes.
97 results demonstrate that TPO can mediate the self-replication of HSC in LTBMC, and provide proof that
98 ng orthogonal from each other: autocatalytic self-replication of oligomers from native monomers and n
99 Rep-Luci genome into mouse lungs, initiating self-replication of Rep-Luci and, accordingly, inducing
100 s of such fundamental biological behavior as self-replication of structural elements and preservation
101                                    Increased self-replication of T cells in RA was indicated by age-i
102 rocesses to facilitate the self-assembly and self-replication of the first biological systems.
103                                              Self-replication of the most primitive HSC produces daug
104  protein-only inheritance requires efficient self-replication of the underlying conformation.
105 ing abasic lesion, leads to rapid, sigmoidal self-replication of the wireframe triangle via cross-cat
106 amic combinatorial library (DCL) may lead to self-replication of this molecule.
107 infection or inflammatory reactions, besides self-replication of tissue resident macrophages.
108 nd control molecular association, catalysis, self-replication or other chemical processes.
109 f the building block between the folding and self-replication pathways and the duration of the fueled
110 , temporally regulated viral expression, and self-replication proceeding to infection of new cells.
111                                          The self-replication process displays parabolic growth patte
112 ditional template units for the nucleic acid self-replication process, resulting in the ultrasensitiv
113 tion of a hydrophobic pocket in water, (iii) self-replication properties and (iv) allosteric properti
114                  Hence, any consideration of self-replication raises one of the most profound questio
115                                     Cellular self-replication requires not only duplicating all cellu
116                                The resulting self-replication scheme is a hypercycle, and computer si
117  Tfl (Thermus flavus)) and compartmentalized self-replication selection, we have evolved polymerases
118 re we describe short-patch compartmentalized self-replication (spCSR), a novel strategy to expand the
119               Feeders of angioblasts yielded self-replication, stellate cell precursors caused lineag
120 hBTSCs were similar in vitro with respect to self-replication, stemness traits, and multipotency.
121                    An artificial (nonliving) self-replication system has been shown to exhibit expone
122 cular recognition principles common to model self-replication systems in chemical biology.
123 amples, outside of biology, of autocatalytic self-replication systems that undergo exponential amplif
124 l that ES cells have an innate programme for self-replication that does not require extrinsic instruc
125  what is probably the most iconic example of self-replication--the ability of a system to replicate,
126 ere is a reasonably wide parameter range for self-replication, there is a subtle balance between the
127 s of beta-cells predominantly occurs through self-replication; therefore, understanding the regulatio
128 rigin of life by driving a primitive form of self-replication through fragmentation.
129                               In particular, self-replication through RNA-catalysed templated RNA syn
130        The data provide direct evidence that self-replication through secondary nucleation occurs alo
131 not only remained intact but were capable of self-replication using native monomers as the substrate.
132 ive ternary complexes, and it was shown that self-replication was conserved.
133                The possibility of optimizing self-replication was explored by controlling the frequen
134  the consequences of hematopoietic stem cell self-replication will assist in the development of new a
135 itical aggregation concentration (CAC), then self-replication will not occur.
136 smallest and simplest known cells capable of self-replication, yet it has a complex architecture with

 
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