ライフサイエンスコーパス: semicircular canal

1 sed by free-floating debris in the posterior semicircular canal.

2 chlea via virus injection into the posterior semicircular canal.

3 es of IK,L in type I hair cells of the mouse semicircular canal.

4 cular swimming, fused otoliths, and abnormal semicircular canals.

5 preparation that received inputs from intact semicircular canals.

6 nit, alpha1a.2, disrupted development of the semicircular canals.

7 ivities before and after inactivation of the semicircular canals.

8 ng from the vestibular rotation sensors, the semicircular canals.

9 utely excised mouse crista ampullaris of the semicircular canals.

10 rmation of their non-sensory components, the semicircular canals.

11 ective continual proliferative growth of the semicircular canals.

12 sule including the cartilage surrounding the semicircular canals.

13 y epithelium of the crista ampullaris of the semicircular canals.

14 ory ganglion, cochlea, saccule, utricle, and semicircular canals.

15 ures that house the sensory epithelia of the semicircular canals.

16 nd complete morphological development of the semicircular canals.

17 circling behaviour, due to reduced or absent semicircular canals.

18 sensory organs and restricted domains of the semicircular canals.

19 of the otocyst that is destined to form the semicircular canals.

20 to sample endolymph flow from both vertical semicircular canals.

21 olymphatic duct and the fusion plates of the semicircular canals.

22 e role of cell death in morphogenesis of the semicircular canals.

23 ecomes progressively restricted to the three semicircular canals.

24 otic vesicle shortly before formation of the semicircular canals.

25 at were separate from the projections of the semicircular canals.

26 bular hair cells in the saccule, utricle and semicircular canals.

27 velocities that are too slow to activate the semicircular canals.

28 nsgenic mice that lack functional horizontal semicircular canals.

29 vestibular endolymph that acts to stimulate semicircular canals.

30 signal requires contributions from multiple semicircular canals.

31 ral malformation of the horizontal (lateral) semicircular canals.

32 r cells, and defects in the formation of the semicircular canals.

33 ivated by stimulation of the otoliths or the semicircular canals.

34 volving the superior, lateral, and posterior semicircular canals.

35 king and have severely truncated cochlea and semicircular canals.

36 g either NT3 or GFP genes, via the posterior semicircular canal, 3 wks prior to, or 5 hrs after, nois

37 s constituent epithelial cells to form three semicircular canals, a central vestibule and a coiled co

38 or parts of the ear include three orthogonal semicircular canals, a central vestibule, a coiled cochl

39 d processes, superiorly positioned posterior semicircular canal, absence of a nuchal torus and a supr

40 odel whereby electro-magnetic input from the semicircular canals activates a vestibular-mesopallial c

41 vity-driven responses of primary otolith and semicircular canal afferents remain intact during both a

42 We found that both irregular otolith and semicircular canal afferents, because of their higher se

43 onents arise from stimulation of otolith and semicircular canal afferents, respectively.

44 ON and TON receive principally utricular and semicircular canal afferents.

45 ent in the apex and all three cristae of the semicircular canal ampullae.

46 to account not only for the gain of a third semicircular canal and crista in gnathostomes, but also

47 However, formation of the lateral semicircular canal and its ampulla is usually unaffected

48 Here we recorded from individual semicircular canal and otolith afferents during walking

49 GVS produced asymmetric activation of both semicircular canal and otolith afferents to the onset ve

50 l computations underlying the integration of semicircular canal and otolith inputs required for accur

51 y sensitive to roll tilt, which co-modulates semicircular canal and otolith organ activity, but not t

52 f afferent fibers innervating the individual semicircular canal and otolith organs was produced by se

53 rons in the caudal cerebellar vermis combine semicircular canal and otolith signals to segregate line

54 alone, with most showing convergence between semicircular canal and otolith signals.

55 d particularly the angle between the lateral semicircular canal and the cochlea indicate a phylogenet

56 ometric morphometric approach to investigate semicircular canal and vestibule shape of a chronologica

57 d by a smaller vestibular organ with thinner semicircular canals and a significant reduction in the n

58 bout the anteroposterior axis, with only two semicircular canals and a single sensory macula.

59 rns the shape of vestibular components - the semicircular canals and ampullae - by conferring anterop

60 vestibular hair cells in the cristae of the semicircular canals and auditory hair cells in the organ

61 development of the dorsolateral otocyst into semicircular canals and cristae through two distinct mec

62 hlear hypoplasia and complete absence of the semicircular canals and cristae.

63 st), otolith formation, morphogenesis of the semicircular canals and differentiation of the otic caps

64 x6 expression is seen throughout the forming semicircular canals and endolymphatic structures.

65 receptor, TrkB, lose all innervation to the semicircular canals and have reduced innervation of the

66 bsd homozygotes lack endolymphatic ducts and semicircular canals and have short cochlear ducts.

67 g-eared mutants show abnormal development of semicircular canals and lack cristae within the ear, whi

68 for complicated stimuli, which activated the semicircular canals and otolith organs and involved both

69 (tilt) in space using cues originating from semicircular canals and otolith organs.

70 in the vestibular system, which includes the semicircular canals and otolith organs.

71 ibular receptors consist of highly conserved semicircular canals and otolith organs.

72 y reflect the stimulus magnitudes handled by semicircular canals and otolith organs.

73 Signals from the receptors, the semicircular canals and otoliths, are carried by the eig

74 ll simultaneously stimulate receptors in the semicircular canals and otoliths.

75 sive loss of all afferent innervation to the semicircular canals and reduced innervation to the utric

76 , at larval stages zebrafish lack functional semicircular canals and rely exclusively on their otolit

77 In young subjects, natural engagement of the semicircular canals and the otolith organs by head rotat

78 regulator, is required for the formation of semicircular canals and their associated sensory cristae

79 ect angular head movements lies in the three semicircular canals and their sensory tissues, the crist

80 ial cells localized at the inner edge of the semicircular canals and to the ampullary and utricular w

81 r ear epithelium, including formation of the semicircular canals and, in some, development of sensory

82 nges in ventilation during engagement of the semicircular canals and/or the otolith organs were measu

83 ular organs, which include angular velocity (semicircular canals) and linear acceleration (otolith or

84 Otolithic, semicircular canal, and anterior lateral line nerves all

85 nclude absence of the anterior and posterior semicircular canals, and a malformed saccule and cochlea

86 s in the inner ear, smaller SAGs, defects in semicircular canals, and abnormal neuromasts on the post

87 ape of the otic vesicle and formation of the semicircular canals, and define at least 20 complementat

88 lled diving Pan-Alcidae displayed compressed semicircular canals, and indistinct occipital sinuses an

89 erves, which innervate the otolithic organs, semicircular canals, and lateral lines, project to seven

90 ibular wall, retained the normal size of the semicircular canals, and prevented the degeneration of i

91 cell proliferation, severe malformations of semicircular canals, and shortened cochleae with ectopic

92 Anatomic features facilitate semicircular canal (angular velocity) prosthetics but in

93 of the vestibule and in the absence of three semicircular canals, anterior and posterior cristae.

94 d posture and the orientation of the lateral semicircular canal are both strongly correlated with phy

95 The semicircular canals are biomechanical sensors responsibl

96 Because semicircular canals are normal in het mice, we conclude

97 s but also angular velocity signals from the semicircular canals are simultaneously used by the brain

98 thus caution against the use of the lateral semicircular canal as a proxy to infer precisely the hor

99 Cerebral MRI showed dysplasia of the semicircular canals as an anatomical correlate of sensor

100 in the nonsensory epithelium of the growing semicircular canals at embryonic day (E) 15.5.

101 l, fore-aft, vertical) for CSs and along the semicircular canal axes for SSs.

102 ursuit preferred-direction vectors along the semicircular canal axes was observed, the sensitivity of

103 The MVI system electrically stimulates semicircular canal branches of the vestibular nerve to c

104 hesis that electrically stimulates the three semicircular canal branches of the vestibular nerve.

105 correlated to the orientation of the lateral semicircular canal, but not to the actual head posture.

106 sal fates such as the endolymphatic duct and semicircular canals by positively regulating genes such

107 Stimulation of the horizontal semicircular canals by yaw rotation increased minute ven

108 findings suggest that disruption of a single semicircular canal can elicit compensatory movement stra

109 volving the superior, lateral, and posterior semicircular canal can have different etiologies, includ

110 Further, while the semicircular canals covary as an integrated module, the

111 The present results show that the semicircular canal crista ampullaris of the toadfish, Op

112 ricle, and a complete loss of the horizontal semicircular canal crista, as well as a fusion of the ut

113 lae, and the central and peripheral zones in semicircular canal cristae.

114 es the peripheral zones of each of the three semicircular canal cristae.

115 This force pushes on the semicircular canal cupula, leading to nystagmus.

116 s Chd7 deficiency have circling behavior and semicircular canal defects and are an excellent animal m

117 Posterior semicircular canal dehiscence is a rare entity, with sim

118 Superior semicircular canal dehiscence is now a well-established

119 Lateral semicircular canal dehiscence is usually associated with

120 The main focus will be on superior semicircular canal dehiscence.

121 is found, although the plane of the lateral semicircular canal departs significantly from horizontal

122 s the organs responsible for this sense; the semicircular canals (detecting angular acceleration) and

123 by showing that the retinoic acid effect on semicircular canal development can be overcome by exogen

124 acent to the BMP4 cell foci prevented normal semicircular canal development.

125 del accounts for observed axis tilt based on semicircular canal directional sensitivity and response

126 In zebrafish and Xenopus, semicircular canal ducts develop when projections of epi

127 Morphogenesis of the semicircular canal ducts in the vertebrate inner ear is

128 asia, and ear defects including deafness and semicircular canal dysgenesis.

129 , and dorsal otic derivatives, including the semicircular canals, endolymphatic duct and utricle, are

130 In central regions of vestibular semicircular canal epithelia, the [K(+) ] in the synapti

131 in central regions of the turtle vestibular semicircular canal epithelia.

132 In generating a semicircular canal, epithelial cells seem to 'disappear'

133 d position using three orthogonally oriented semicircular canals; even slight changes in their shape

134 There are the typical three semicircular canals extending from the utricle, with the

135 k cristae within the ear, while in van gogh, semicircular canals fail to form altogether, resulting i

136 Zebrafish semicircular canals form from invaginations in the otic

137 rom the dorsal otic vesicle within which the semicircular canals form.

138 hour intervals during the critical stages of semicircular canal formation (E6-E7).

139 The defect in semicircular canal formation is due to problems in the i

140 BMP4 antagonists disrupt semicircular canal formation, as does exposure to retino

141 survival in the ear, for HC differentiation, semicircular canal formation, statoacoustic ganglion (SA

142 and disrupted hair cell differentiation and semicircular canal formation.

143 pment, Nor-1 is expressed exclusively in the semicircular canal forming fusion plates.

144 have been integrated into the assessment of semicircular canal function in patients with vestibular

145 inner ear that selectively impairs superior semicircular canal function.

146 , we examine the steps involved in posterior semicircular canal gene delivery in the adult mouse inne

147 Semicircular canal geometries underwent distinct changes

148 Here we show that semicircular canal hair cells generate a mechanical nonl

149 ein 2 (Bmp2) results in absence of all three semicircular canals; however, the common crus and ampull

150 We imaged the horizontal semicircular canal (HSCC) crista and cupula of toadfish,

151 brane overlying the crista ampullaris of the semicircular canal, important for sensing rotation of th

152 The injection of RNP-EVs via the posterior semicircular canal in 4-week-old Myo7a(WT/Sh1) mice resu

153 f the associated non-sensory components, the semicircular canals, in vertebrate inner ears.

154 well-developed olfactory lobes and anterior semicircular canals, indicating acute olfaction and vest

155 ing activity after canal occlusions, but the semicircular canal input is critical for updating the ne

156 eives highly overlapping otolithic organ and semicircular canal input, and we propose that this regio

157 and the horizontal plane to determine their semicircular canal input.

158 d ventral MgON) receive mainly utricular and semicircular canal inputs, suggesting vestibular roles.

159 owever, the endolymphatic fluid space in the semicircular canals is diminished and the roof of the am

160 In both cases the morphogenesis of the semicircular canals is disrupted.

161 nt adults, the endolymph-filled lumen of the semicircular canals is severely reduced.

162 nitially includes the sensory regions of the semicircular canals, known as the cristae ampullaris, bu

163 -/- mutants showed an absence of the lateral semicircular canal, lateral ampulla, utriculosaccular du

164 nd vestibulo-ocular reflexes mediated by the semicircular canals, little is known about the role of t

165 ay variable asymmetric lateral and posterior semicircular canal malformations, as well as defects in

166 During inner ear semicircular canal morphogenesis in zebrafish, patterned

167 and nuchal torus) and temporal labyrinthine (semicircular canal) morphology with the Neandertals.

168 The horizontal semicircular canal nerve of the toadfish, Opsanus tau, w

169 Each semicircular canal nerve projects to distinct regions of

170 eling the peripheral axons of the horizontal semicircular canal nerve with biocytin after nerve regro

171 Semicircular canal nerves project primarily to ventral r

172 egregated projections from all otolithic and semicircular canal nerves, whereas the ventral DON and T

173 re recorded from chinchillas after bilateral semicircular canal occlusion.

174 Ocular motor, semicircular canal-ocular, and semicircular canal-otolit

175 smotic sisomicin solution into the posterior semicircular canal of adult mice.

176 bers and varicosities were visualized in the semicircular canal of red-eared turtles (Trachemys scrip

177 he skull was reconstructed as if the lateral semicircular canal of the bony labyrinth was aligned hor

178 s have assumed that the plane of the lateral semicircular canal of the inner ear lies parallel to the

179 behaviour due to truncations of the lateral semicircular canal of the inner ear.

180 The semicircular canals of miniaturized frogs are the smalle

181 surgery, we imaged the lateral and posterior semicircular canals of patients with Meniere's disease o

182 elds by electromagnetic induction within the semicircular canals of the inner ear [4].

183 es head rotations, which are detected by the semicircular canals of the inner ear.

184 The semicircular canals of the mammalian inner ear are deriv

185 elineated whether information from all three semicircular canals or just the horizontal canals, which

186 Ocular motor, semicircular canal-ocular, and semicircular canal-otolith interaction assessments sugge

187 ing focused on the otolith-ocular reflex and semicircular canal-otolith interaction.

188 lectrode placement with respect to bilateral semicircular canal pairs or alterations of the bipolar s

189 utgrowth and a failure of fusion to form the semicircular canal pillars.

190 ons and the anatomy and firing properties of semicircular canals precisely predicted these perception

191 lysis revealed smaller posterior and lateral semicircular canal primordia and a delay in the canal fu

192 While there is considerable evidence that a semicircular canal prosthesis that senses angular head v

193 Preliminary studies indicate the semicircular canals provide a necessary component of the

194 rior petrosal surface (PPS) to the posterior semicircular canal (PSC; PPS-PSC) were made on thin-cut

195 ans are unloaded in microgravity, the fetus' semicircular canals receive high levels of stimulation d

196 Their enlarged semicircular canals reflect a highly refined organ of eq

197 The vestibular semicircular canals respond to angular acceleration that

198 ional rotation in the planes of the vertical semicircular canals revealed relative sparing of vertica

199 The vestibular apparatus, including three semicircular canals, saccule, utricle, and their associa

200 ttery [video head-impulse test (vHIT) of all semicircular canals (SCC)], air-conducted cervical/ocula

201 In particular, the morphology of the semicircular canals (SCCs) of the endosseous labyrinth h

202 Furthermore, nonsensory structures such as semicircular canals seemed to display a greater suscepti

203 The height, width and length of all three semicircular canals show functional morphological adapta

204 ad significantly greater horizontal-vertical semicircular canal signal convergence than did neurons n

205 ess or near target viewing demonstrated that semicircular canal signals are necessary sensory cues fo

206 It is traditionally believed that semicircular canal signals drive compensatory responses

207 y storage network is to temporally integrate semicircular canal signals, so that they may be used to

208 morphogenetic program that shapes the three semicircular canals (SSCs) must be executed with extreme

209 mp2 is strongly expressed in the prospective semicircular canals starting from the canal outpouch sta

210 ze that the unparalleled modification of the semicircular canal system represented a key 'point of no

211 an independent perspective by looking at the semicircular canal system, one of the main sense organs

212 r nuclei that overlapped with the horizontal semicircular canal terminal fields, whereas saccular aff

213 laris, sensory structures at the base of the semicircular canals that are critical for vestibular fun

214 ion can induce electric fields in the pigeon semicircular canals that are within the physiological ra

215 elds by electromagnetic induction within the semicircular canals that is dependent on the presence of

216 vestibular crista, the sensory organ of the semicircular canals that sense head rotation.

217 ipital linear accelerations and input to the semicircular canals that varied across motion paradigms.

218 Among the three semicircular canals, the superior canal was the most sus

219 vestibular inputs from both the otoliths and semicircular canals to maintain equilibrium relative to

220 n the inner ear, the otolith organs, and the semicircular canals transduce self-motion in an egocentr

221 that stimulated both the otolith organs and semicircular canals (upright roll and on tail yaw) produ

222 cture of the inner ear, which contains three semicircular canals used to detect motion of the head in

223 res found in the adult, including the mature semicircular canals, utricle, saccule, cochlear duct, en

224 Contributions of semicircular canal versus otolith organ signals were inv

225 tegy that markedly differs from that used by semicircular canal vestibular afferents to encode rotati

226 of physiologically characterized horizontal semicircular canal vestibular nerve afferents in the toa

227 are usually attributed to the dysfunction of semicircular canal vestibulo-ocular reflexes, as they ha

228 When the semicircular canals were inactivated, horizontal eye mov

229 Rotations that excited the semicircular canals were much less effective in inducing

230 Among the nonsensory structures, the semicircular canals were the most sensitive and the endo

231 ntation-independent rotation signal from the semicircular canals, which could be useful in compensati

232 mporally integrated rotation signal from the semicircular canals, which is critical for computing hea

233 To assess the specific contributions of the semicircular canals without altering tonic VIIIth nerve