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1 relied on isolation from natural sources and semisynthesis.
2 nucleophile of DmTR with a Sec residue using semisynthesis.
3 sual take on the age-old practice of steroid semisynthesis.
4 nal thioester are important intermediates in semisynthesis.
5 product of taccalonolide B, was generated by semisynthesis.
6 te analogue motifs in the context of protein semisynthesis.
7 expanding the scope of protein synthesis and semisynthesis.
8 ata, and some were additionally confirmed by semisynthesis.
9 d form of T beta R-I, prepared using protein semisynthesis.
10 enzoyl)paclitaxel (N-AB-PT), was prepared by semisynthesis.
11 nd C-10 acetate), a precursor for paclitaxel semisynthesis.
12 has been summarized to prepare paclitaxel by semisynthesis.
13 main obtained in our laboratory by enzymatic semisynthesis.
14 uted Arg or by other residues using chemical semisynthesis.
15 h substantially expands the scope of protein semisynthesis.
16 an only be produced recombinantly or through semisynthesis.
17 on/functionality not readily accessible from semisynthesis.
18 olated compounds and derivatives obtained by semisynthesis (9a-11) hinted at the location of the biar
19 e chemical modification of natural products (semisynthesis), a method ill-equipped to combat rapidly
20                                    Our short semisynthesis and analogue-oriented synthesis approaches
21                In this work, we used protein semisynthesis and fluorescence anisotropy assays to expl
22                          Here, we report the semisynthesis and spectroscopic characterization of a se
23 e present study describes the application of semisynthesis and total synthesis to reveal key structur
24 igned lincosamides otherwise inaccessible by semisynthesis and underpins a platform for the discovery
25                     Here, we adapt a protein semisynthesis approach to generate full-length variants
26                                          The semisynthesis approach yielded significant quantities of
27 tes the reliance on kinase-based or chemical semisynthesis approaches, making it broadly applicable t
28 thesis route is not to displace isolation or semisynthesis as a means of generating the natural produ
29                          Here we use protein semisynthesis by expressed protein ligation to systemati
30 ng of E3 mechanisms, and here we use protein semisynthesis, chemical rescue, microscale thermophoresi
31                                      Protein semisynthesis-defined herein as the assembly of a protei
32  Mad2 protein obtained using intein-mediated semisynthesis do not form C-Mad2 on their own.
33 cess to analogues that cannot be prepared by semisynthesis from natural ingenol.
34  yet have heretofore only been available via semisynthesis from naturally occurring chlorophylls.
35 mbergris, Ambrox is produced industrially by semisynthesis from sclareol, a diterpene-diol isolated f
36 essible from natural product derivatization (semisynthesis) has resulted in the identification of a n
37 ex fermentation products, a process known as semisynthesis, has been an important tool in the discove
38            Given the inherent limitations of semisynthesis, however, accessing derivatives of (+)-ple
39 expect our approach will extend the scope of semisynthesis in protein engineering.
40  Arginylated alphaS has been studied through semisynthesis involving multipart native chemical ligati
41 search into a commercially viable paclitaxel semisynthesis is also described.
42 a topic of great interest for over 50 years, semisynthesis is often how synthetic variants of these n
43                                    A protein semisynthesis method-expressed protein ligation-is descr
44        Here, we use a combination of protein semisynthesis, NMR, and enzymological analysis to charac
45                                We report the semisynthesis of a fluorescent glutamate sensor protein
46 dge, this work represents the first reported semisynthesis of a polytopic membrane protein and highli
47                                We report the semisynthesis of a selenocysteine (Sec) derivative of th
48      Expressed protein ligation (EPL) allows semisynthesis of a target protein with site-specific inc
49 ll lysates and applied this strategy for the semisynthesis of a variety of proteins including an acet
50 r, this novel transformation facilitates the semisynthesis of a wide variety of new analogues for str
51 he analysed cocoa beans, were obtained after semisynthesis of cocoa bean polymers with (+)-catechin a
52 he first report concerning the isolation and semisynthesis of dimeric to pentameric procyanidins from
53  This technology is based on the streamlined semisynthesis of DNA-barcoded nucleosome libraries with
54 e the production yields of Taxol and for the semisynthesis of drug analogs bearing modified aroyl gro
55  single expression system, as well as by the semisynthesis of dual posttranslationally modified histo
56 tation method that bypasses the low-yielding semisynthesis of epirubicin (4'-epidoxorubicin) and 4'-e
57                               The successful semisynthesis of full-length histone H2B modified by the
58              An efficient, new, and scalable semisynthesis of glucan synthase inhibitors 1 and 2 from
59          Here we describe an approach to the semisynthesis of libiguin A and its close analogues 1-3
60 licing under a range of conditions, enabling semisynthesis of modified proteins both in vitro and in
61  moieties in bilin metabolism, we report the semisynthesis of mono- and diamides of biliverdin IXalph
62 nally, the chemistry has applications in the semisynthesis of monodisperse polymers based on protein
63 we overcome this limitation by using protein semisynthesis of Na(v)1.5 in live cells and carry out co
64        In this contribution, we describe the semisynthesis of NaK, a bacterial nonselective cation ch
65                                              Semisynthesis of natural product derivatives combines th
66  application of biocatalysis in enabling the semisynthesis of paclitaxel.
67 sters are key intermediates in the synthesis/semisynthesis of proteins and of cyclic peptides by nati
68 ecific protein bioconjugation, synthesis and semisynthesis of proteins and peptides, and chemoproteom
69 ptide ligases have not been utilized for the semisynthesis of proteins in live cells.
70     Recent advancements in the synthesis and semisynthesis of proteins made it possible to prepare se
71 pments in the area of chemical synthesis and semisynthesis of proteins offer great solutions to the e
72    Synthetic chemists exploit inteins in the semisynthesis of proteins with or without nonribosomal m
73 ynthesis of complex disulfide-rich peptides, semisynthesis of proteins, and peptide/protein labelling
74 n, which is widely used in the synthesis and semisynthesis of proteins, has been going through severa
75  unnatural amino acid technology permits the semisynthesis of ratiometric fluorescent sensor proteins
76            Here we report a strategy for the semisynthesis of site-specifically ubiquitylated histone
77 ld significantly facilitate the chemical and semisynthesis of synthetically challenging proteins from
78                       We report an efficient semisynthesis of the cholestane steroidal alkaloid (-)-v
79                                          For semisynthesis of the KvAP channel, we developed a modula
80         In this contribution we describe the semisynthesis of the potassium channel, KcsA.
81 echnology was first demonstrated through the semisynthesis of the tick-derived chemokine-binding prot
82 l(-)(1) in shake flasks) and further in situ semisynthesis of warfarin.
83 otein backbone were introduced using protein semisynthesis or in vivo nonsense suppression approaches
84 an be advantageously complemented by protein semisynthesis or total chemical synthesis.
85  gene cluster manipulation, total synthesis, semisynthesis, or a combination of these methods, with a
86 l products are almost invariably prepared by semisynthesis, or chemical transformation of the isolate
87 pped with a C-terminal membrane anchor via a semisynthesis strategy.
88 ins play an important role in modern protein semisynthesis techniques.
89 in ligation is a valuable method for protein semisynthesis that involves the reaction of recombinant
90                                       In the semisynthesis, the NaK polypeptide is assembled from a r
91                         We have used protein semisynthesis to generate nine site-specifically ubiquit
92 rminal tail phosphorylation, we used protein semisynthesis to insert stoichiometric and site-specific
93                      Herein, we used protein semisynthesis to investigate, for the first time, the ef
94          Herein, we use intein-based protein semisynthesis to pair a synthetic naphthoquinone amino a
95          In this study, we have used protein semisynthesis to selectively perturb site 1 within the f
96                                      We used semisynthesis to substitute aspartate 66 in the selectiv
97 n of catharanthine and vindoline, from which semisynthesis to vinblastine occurs.
98           A complete approach, not wedded to semisynthesis, toward both the A-ring and CD-ring is rep
99               Using a combination of protein semisynthesis, two-dimensional infrared (2D IR) spectros
100 ly, we demonstrate a strategy for papaverine semisynthesis using hydrogen peroxide as an oxidizing ag
101 of these chemical strategies, namely histone semisynthesis via the chemical ligation of peptide fragm
102                                      Protein semisynthesis was used to introduce d-Alanine into the s
103 of planar rigidity in ordering this protein, semisynthesis was used to substitute porphyrin by two hy
104                                Using protein semisynthesis, we characterize the effect of cell cycle-
105 cribe a new method to produce histone H2B by semisynthesis with an engineered sortase transpeptidase.
106 reagents for protein cyclization and protein semisynthesis, with the latter illustrated through the m

 
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