ライフサイエンスコーパス: sequence analyses

1 e blocks into two groups consistent with the sequence analyses.

2 ing integrated, high-throughput, genome-wide sequence analyses.

3 e the lack of any obvious abnormality in the sequence analyses.

4 Disease-causing mutations were assessed by sequence analyses.

5 performed phenotypic, functional, and viral sequence analyses.

6 erase chain reaction (RT-PCR) and nucleotide sequence analyses.

7 es, they are ideal subjects for whole genome sequence analyses.

8 undancy and improve the performance of other sequence analyses.

9 repeats analysis, and by fim3, prn, and ptxP sequence analyses.

10 f the DISC1 protein in the light of in-depth sequence analyses.

11 e centromeric DNA by genetic mapping and DNA sequence analyses.

12 polymerase chain reaction, cloning, and DNA sequence analyses.

13 e of S282T was found by population or clonal sequence analyses.

14 gment length polymorphism, and 16S rRNA gene sequence analyses.

15 , confounds characterization by conventional sequence analyses.

16 n parallel for use in downstream multiplexed sequence analyses.

17 research labs worldwide for next-generation sequence analyses.

18 ated intestinal organoids, and performed RNA sequence analyses.

19 old at diagnosis) and performed whole-exome sequence analyses.

20 c cotton through PCR amplification assay and sequencing analyses.

21 ytometry, real-time quantitative PCR, or RNA sequencing analyses.

22 her time points, and incorporate further RNA sequencing analyses.

23 of Mut268 compared to WT using targeted deep-sequencing analyses.

24 mmunoprecipitation sequencing and direct RNA sequencing analyses.

25 tem cells using combined microarray and deep sequencing analyses.

26 umor subpopulations than do traditional bulk sequencing analyses.

27 precipitation-microchip (ChIP-chip) and ChIP-sequencing analyses.

28 s revealed by morphological and unbiased RNA-sequencing analyses.

29 lomic, messenger RNA quantification, and RNA-sequencing analyses.

30 d in-situ RNA technology and single-cell RNA-sequencing analyses.

31 permuted data and validated in targeted deep-sequencing analyses.

32 mbryos and performed whole transcriptome RNA sequencing analyses.

33 itivity, RFLP patterns, and 16S rRNA and ITS sequence analyses, 42 of 750 isolates with Salinispora-l

34 nd suggest that applying simple rules of DNA sequence analyses across species may be difficult.

35 One major finding from microbial sequencing analyses after Roux-en-Y gastric bypass is th

36 olate and performed a variety of comparative sequence analyses against N. meningitidis reference geno

37 Sequence analyses also revealed the existence of CspZ ph

38 TCRbeta and CD3 subunit protein sequence analyses among Gnathostomata species show that

39 Sequence analyses and a 1.9 A resolution crystal structu

40 Sequence analyses and genetic mapping show that the sex-

41 iated with Populus deltoides using rRNA gene sequence analyses and how these vary with tree and wood

42 pecificity, we performed detailed amino acid sequence analyses and investigated the catalytic and spe

43 Sequence analyses and phylogenetic reconstructions sugge

44 Sequence analyses and site-directed mutagenesis establis

45 By combining dual RNA-sequencing analyses and cell imaging, we show that the l

46 d workflows for PDX exome-sequencing and RNA-sequencing analyses and for evaluating growth.

47 By performing interspecies comparative RNA sequencing analyses and functional assays, we explored t

48 Second, we perform mapping-by-sequencing analyses and identify a 3.9-Mb genomic interv

49 We performed cDNA and direct RNA sequencing analyses and revealed an extremely complex tr

50 We performed RNA-sequencing analyses and used systems biology approaches

51 mic hybridization microarrays and breakpoint sequence analyses, and we identified 17 unique CNVs, inc

52 low cytometry, high-coverage single-cell RNA sequencing analyses, and cell fate assays to chart basop

53 in RNA-mediated gene silencing, RNA and ChIP sequencing analyses, and metabolite profiling, we show h

54 However, the assumptions that underlie sequence analyses are based on experimental results that

55 Multilocus and whole-genome sequence analyses are becoming the cornerstones of studi

56 Whole genome and whole exome sequencing analyses are under way to study cases of DILI

57 Deep-sequencing analyses are used to determine the relative f

58 sity (16S rRNA gene amplicon and metagenomic sequencing analyses), as well as the specific bacterial

59 Using PCR and DNA sequence analyses, atcS and atcR were demonstrated to be

60 Sequence analyses based on our results imply that foldab

61 een identified by proteomics and comparative sequence analyses, but functional data are lacking for t

62 tion, isolates were subjected to comparative sequence analyses by use of the internal transcribed spa

63 rter plasmid transfection and genomic run-on sequence analyses confirm that the HLA-A transcriptional

64 Sequence analyses confirmed its identity to be the human

65 Promoter sequence analyses, deletion studies, mutagenesis studies

66 RNA sequencing analyses demonstrated that GPBAR1 agonism mod

67 t in quantity and quality for proteomics and sequencing analyses, demonstrating the utility of this m

68 Structure-oriented sequence analyses described here predicted that the KLF1

69 Sequence analyses detected the induction of high frequen

70 Single-cell RNA sequencing analyses detected activated B cells, germinal

71 ChIP sequencing analyses displayed enrichment of ZBED6 bindin

72 a public database search against PubMed and sequence analyses, e.g. sequence and structural homology

73 Sequence analyses establish that while both PRO(FUR) and

74 Comparative sequence analyses expand the array of locus-specific mut

75 full-length and 5' partial 16S gene and sodA sequence analyses failed to correctly assign all strains

76 Sequencing analyses followed by case control and family-

77 g that gyrB is superior to 16S gene and sodA sequence analyses for VGS species identification.

78 Further sequence analyses found a duplication of the tRNA(Ser)UC

79 mal evolution, our recent large-scale coding-sequence analyses from vertebrates and invertebrates pro

80 Dual species RNA-sequencing analyses from single and mixed biofilms revea

81 RNA sequencing analyses from two different tissues of Stevia

82 ects in the cellular assay, but not in vitro Sequencing analyses further demonstrated that Hsp90 incr

83 Alignment-free sequence analyses have been applied to problems ranging

84 Sequence analyses have provided a wealth of information

85 High-throughput sequence analyses have revealed the composition of the g

86 Preliminary sequence analyses have shown that the virus is a reassor

87 Mapping-by-sequencing analyses have largely required a complete ref

88 Deep sequencing analyses have shown that a large fraction of

89 Whole-genome sequencing analyses highlight the value of regulatory an

90 The collection of structures and sequence analyses highlighted additional residues that m

91 Our sequence analyses however predicted that members of one

92 Mutational and protein sequence analyses identified a motif in the N terminus o

93 Whole-exome sequence analyses identified disease-causing mutations i

94 Comprehensive coding sequence analyses identified missense mutations clustere

95 Sequence analyses identified structural features of tran

96 RNA-sequencing analyses identified a robust enrichment of th

97 enomic hybridization arrays, and whole-exome sequencing analyses identified homozygous pathogenic var

98 In this study, RNA sequencing analyses identified KLK7 as the most abundant

99 Next generation sequencing analyses identified specific transcriptome an

100 Chromatin immunoprecipitation sequencing analyses identified the genes possessing regu

101 pproaches, including RNA-sequencing and ChIP-sequencing analyses, immunohistochemistry-based tissue m

102 s with idiopathic short stature we performed sequence analyses in 428 families.

103 The three motifs were identified by sequence analyses in the region upstream of the VP2 star

104 etic causes for ET, we performed whole-exome sequencing analyses in a large Spanish family with ET, i

105 Genomic sequencing analyses in seven affected individuals uncove

106 immunoprecipitation [ChIP] followed by deep sequencing) analyses in brown adipose tissue showed that

107 ), from 1992 through 2015, and performed RNA sequence analyses, including isoform-specific analyses.

108 Sequence analyses indicate origin of the family in the c

109 Sequence analyses indicate that CvAOX has 10 exons with

110 Comparative sequence analyses indicate that many fungal species carr

111 Amongst these Rbmx-like genes, DNA sequence analyses indicate that two other mouse autosoma

112 However, Northern blot and small RNA deep sequencing analyses indicate that DRH-1 acts to enhance

113 Further sequence analyses indicated that ICE6013 is more closely

114 Sequence analyses indicated that SECE2 proteins are foun

115 Here, sequence analyses indicated that the cluster exists in f

116 pectroscopic analysis followed by amino acid sequence analyses indicated that the protein was adenosi

117 dered V. cholerae more resistant to H2O2 RNA sequencing analyses indicated that OxyR1-activated oxida

118 Many Next Generation Sequencing analyses involve the basic manipulation of in

119 On the basis of amino acid sequence analyses, KijD3 has been proposed to be an FAD-

120 t parasite in an infected bird using PCR and sequencing analyses may be influenced by season and host

121 tric-morphometric analyses with evolutionary sequence analyses of 10,322 protein-coding genes as well

122 We performed DNA sequence analyses of 48 colorectal tumors (from 16 patie

123 Sequence analyses of 552 Type ISP enzymes showed that th

124 e-specific HPV infections persisted, and DNA sequence analyses of a subset revealed that all were var

125 In WES and targeted exome sequence analyses of an infant with severe IBD character

126 Genome sequence analyses of bacterial plant pathogens are revea

127 Sequence analyses of CHIKV from sixteen samples revealed

128 ty of the genome by undertaking whole-genome sequence analyses of clonal populations of cells that ha

129 We performed exome sequence analyses of germline DNA from 20 patients with

130 Earlier sequence analyses of H7N9 hemagglutinin (HA) point to am

131 This was corroborated by sequence analyses of HCV from a liver transplant recipie

132 Here, using RT-PCR and sequence analyses of head-to-tail-ligated (-) strands, w

133 ith the phosphate moiety that, together with sequence analyses of homologues, indicate a novel FMN bi

134 Genome sequence analyses of in vitro-derived ACT-451840-resista

135 Whole-transcriptome sequence analyses of liver tissues from mice and patient

136 Sequence analyses of outbreak isolates revealed that C.

137 mutations across the mitochondrial genome by sequence analyses of paired tumor and normal tissue samp

138 We performed RNA sequence analyses of pairs of colon tumor and nontumor t

139 Sequence analyses of pathogen genomes facilitate the tra

140 Comparative sequence analyses of portions of the locus AFUA_3G08990,

141 Here we perform comparative repertoire sequence analyses of pre-selection and post-selection TC

142 Comparative sequence analyses of predicted proteins revealed expecte

143 RNA sequence analyses of rrc1-3 identified a large number of

144 Editing was further informed by sequence analyses of TALe genes in 63 Xoo strains, which

145 ates were identified as F. novicida based on sequence analyses of the 16S ribosomal RNA, pgm, and pdp

146 restriction fragment length polymorphism and sequence analyses of the 16S rRNA genes.

147 Sequence analyses of the breakpoint junctions suggest th

148 Structural and sequence analyses of the BT_1012 protein identifies it a

149 er X-family polymerase, since computer-based sequence analyses of the C. elegans genome failed to sho

150 Population and/or deep sequence analyses of the HCV NS3, NS5A, and NS5B genes w

151 Sequence analyses of the influenza A virus (IAV) surface

152 00% concordant with results from comparative sequence analyses of the ITS-1 region and showed excelle

153 ied morphologically and molecularly based on sequence analyses of the nuclear ribosomal RNA (nrRNA),

154 Sequence analyses of the putative B. burgdorferi Hfq pro

155 Finally, sequence analyses of the virulence determinant CagA reve

156 Phylogenetic and sequence analyses of their Hox and other homeobox genes,

157 amplifications; and library preparation and sequence analyses of these amplification products.

158 Sequence analyses of these TIPs revealed homology to pro

159 Sequence analyses of three swo1(-) alleles and the one g

160 Sequence analyses of various GAS M-Prts have shown that

161 Comparative sequence analyses of viral RNA extracted from intestinal

162 Furthermore, sequence analyses of ZmYuc1 complementary DNA and genomi

163 Here we report exome-sequencing analyses of 20,791 individuals with type 2 di

164 Here we performed whole-genome sequencing analyses of 426 individuals-comprising 50 eth

165 We performed whole-exome sequencing analyses of 75 patients from 40 families with

166 Mechanistically, single-cell RNA-sequencing analyses of a mesenchymal niche model showed

167 lu exon peptide in its catalytic domain, RNA sequencing analyses of A-to-I editing demonstrate that b

168 We performed whole-exome sequencing analyses of blood samples from an unselected

169 with Sendai virus and conducted single-cell-sequencing analyses of CD8(+) T lymphocytes responsive t

170 RNA-sequencing analyses of cortical and striatal micropunche

171 ularization PCR analysis and high-throughput sequencing analyses of CSR junctions and a chromosomal b

172 We performed shotgun metagenomic sequencing analyses of feces from wild-type mice and mic

173 logical surveys for MCPyV seropositivity and sequencing analyses of healthy human skin suggest that M

174 RNA-sequencing analyses of hepatic macrophages in this model

175 RNA-sequencing analyses of high-order mutants indicate that

176 Comparative RNA sequencing analyses of Hoxa(-/-) and WT hematopoietic st

177 Chromatin immunoprecipitation-sequencing analyses of human YAP1-MAMLD1-positive ependy

178 performed chromatin immunoprecipitation and sequencing analyses of intestinal crypts to identify gen

179 alterations through ultrasensitive targeted sequencing analyses of matched cfDNA and white blood cel

180 We performed whole transcriptome sequencing analyses of metastatic human breast cancer ce

181 In whole-exome sequencing analyses of more than 1000 children with IBD

182 Deep-sequencing analyses of mRNA and immunoblotting revealed

183 Deep-sequencing analyses of NS3 protease inhibitor-treated HC

184 ere determined to be active by global run-on sequencing analyses of NSPCs.

185 In whole-exome sequencing analyses of patients from families with a his

186 RNA sequencing analyses of primary colonic organoids showed

187 of Immunity, Zeng et al. use single-cell RNA sequencing analyses of rare samples to shed light on the

188 Sequencing analyses of samples from TSC patients suggest

189 h following transplant were confirmed by RNA-sequencing analyses of serial ITx biopsies.

190 uman T-ALL, we performed DNA copy number and sequencing analyses of T-ALL diagnostic specimens, revea

191 landscapes of somatic mutations through deep-sequencing analyses of the coding exomes and whole genom

192 We performed RNA sequencing analyses of the dentate gyrus and entorhinal

193 terminate colitis) and performed whole-exome sequencing analyses of the microdissected tumor and matc

194 Next-generation sequencing analyses of tumor tissues revealed 49 variant

195 RNA- and ATAC-sequencing analyses of tumor-derived cell lines revealed

196 , we performed polymerase chain reaction and sequence analyses on this cancer.

197 Flow cytometric, bulk, and single-cell RNA-sequencing analyses on small intestine (SI) MMC9s were p

198 Using GUIDE-seq and targeted deep sequencing analyses performed with both Cpf1 nucleases,

199 ar to the ammonia-oxidizing bacteria, genome sequence analyses point to a completely unique biochemis

200 Sequence analyses previously revealed that CRT1 contains

201 Rapidly developing single-cell sequencing analyses produce more comprehensive profiles

202 Additionally, sequence analyses reveal that a greater-than-expected fr

203 Sequence analyses reveal that ape parasites lack host sp

204 Sequence analyses reveal that heme-sensitive antibodies

205 Behavioral, stereological, and whole-genome sequence analyses reveal that paternal cognition improve

206 normal down-regulating cues, and NFATc1 ChIP-sequencing analyses reveal a marked enrichment of NFATc1

207 Third, our sequencing analyses reveal a single nucleotide polymorph

208 Single-cell RNA sequencing analyses reveal four distinct AM sub-clusters

209 r affinity- and bisulfite-based whole-genome sequencing analyses reveal global enhancer hypomethylati

210 Further genetic and sequencing analyses reveal that DMAD is essential for de

211 Exome sequence analyses revealed a novel mutation (c.1490C>T,

212 Sequence analyses revealed a potential nuclear localizat

213 PCR and sequence analyses revealed a recombination event involvi

214 morphism of small subunit rDNA, cloning, and sequence analyses revealed distinct shifts such that, at

215 Sequence analyses revealed five prophage regions, a CRIS

216 RNA sequence analyses revealed increased expression of a SIG

217 Furthermore, sequence analyses revealed that a loss or overexpression

218 16S rRNA amplicon sequence analyses revealed that acetate/lactate mainly e

219 Comparative sequence analyses revealed that RPA2580 belongs to a sep

220 Sequence analyses revealed that the Q-satRNA multimers f

221 Transcriptional profiling coupled with sequence analyses revealed that the sense-strand transcr

222 RNA-sequencing analyses revealed differential gene expressio

223 RNA sequencing analyses revealed dramatic up-regulation of t

224 ytes were in a more activated state, and RNA sequencing analyses revealed hyperactivation of several

225 Deep sequencing analyses revealed that [KIL-d] selectively in

226 emethylation treatment and bisulfite genomic sequencing analyses revealed that downregulation of Rab2

227 nd chromatin-immunoprecipitation followed by sequencing analyses revealed that ENL binds to acetylate

228 RNA sequencing analyses revealed that increased ANAC017 expr

229 High-throughput sequencing analyses revealed that loss of ATM/ATR phosph

230 Deep sequencing analyses revealed that mature miR-124 and tar

231 RNA-sequencing analyses revealed that more than 250 genes ar

232 Bulk RNA sequencing analyses revealed that the sonoselective low-

233 Our RNA sequencing analyses revealed that two antioxidant genes

234 RNA sequencing analyses revealed the deregulation of marker

235 Recent large-scale sequencing analyses revealed the loss of several chromat

236 Molecular modeling and high-throughput sequencing analyses revealed the molecular basis of AKAP

237 filing, by parallel micro-array and deep RNA sequence analyses, reveals many other alterations in pre

238 Sequence analyses show NaPi-2b has a PDZ binding motif a

239 Genome sequence analyses show that genome reduction is an ongoi

240 Sequence analyses show that Orsay is related to nodaviru

241 DNA and protein sequence analyses show that Plk5 shares more similaritie

242 Comparative sequence analyses show that the yar gene is conserved in

243 e positive for Zika virus RNA by RT-PCR, and sequence analyses showed highest identities with Zika vi

244 Breakpoint sequence analyses showed nonrecurrent deletions in 5/6 f

245 Sequence analyses showed signatures of deviations from n

246 of 16S rRNA, rpoB, and gyrB gene comparative sequence analyses showed that A47 does not belong to any

247 Sequence analyses showed that all exons of GhCesA2-A(T)

248 Whole exome sequence analyses showed that both individuals had a hom

249 Sequence analyses showed that MacA contains two high-den

250 rescence in situ hybridization, PCR, and DNA sequence analyses showed that the distal inv(6) breakpoi

251 Sequence analyses showed that the Guangdong H7N9 virus i

252 Comparative RNA sequencing analyses showed reduced expression of mitotic

253 In addition, chromatin immunoprecipitation sequencing analyses showed that a subset of hypomethylat

254 Sequencing analyses showed that four out of five sequenc

255 Chromatin immunoprecipitation and sequencing analyses showed that MTG16 bound to promoters

256 Chromatin immunoprecipitation sequencing analyses showed that PFKFB3 is required for c

257 Transcriptomic and genome sequencing analyses showed that QnrB promoted gene abund

258 Moreover, RNA sequencing analyses showed that sarA mutants exhibited s

259 Deep-sequencing analyses showed that sorting of vd-sRNAs into

260 itation [ChIP] combined with high-throughput sequencing) analyses showed that MLL-AF4 and MLL-ENL fus

261 In this context, sequence analyses, site-directed mutagenesis, and region

262 Here, integrating full-genome and deep-sequencing analyses, structural information, and in vitr

263 siderations can inform other high-throughput sequencing analyses such as ChIP-seq and RNA-seq.

264 Structural and sequence analyses suggest that all Pcdh isoforms will di

265 Furthermore, expression and sequence analyses suggest that the SBP1-mediated transit

266 Collectively, the phylogenetic and genomic sequence analyses suggest that Yoka poxvirus is the prot

267 ing, genomic context and comparative protein sequence analyses suggested that CheV interacts with spe

268 Moreover, sequence analyses suggested the autoinhibitory mechanism

269 istry and serotyping as well as whole-genome sequencing analyses, take several days.

270 ith biallelic WDR72 mutations by whole exome sequence analyses that perfectly segregated with the ena

271 study provided the data for fine resolution sequence analyses that would yield insight into the mole

272 We previously reported high-throughput RNA sequencing analyses that identified heightened expressio

273 S rRNA pyrosequencing and shotgun metagenome sequencing analyses, the most abundant species represent

274 We performed DNA sequence analyses to detect bacterial species in 945 CF

275 n engineering that exploits phylogenetic and sequence analyses to identify amino acid substitutions t

276 We performed RNA sequence analyses to identify metabolic pathways involvi

277 s combined with large-scale phylogenetic and sequence analyses to predict the existence of a core set

278 We performed whole-exome sequencing analyses to characterize the genetic landscap

279 congestion, and performed microarray and RNA-sequencing analyses to identify gene expression patterns

280 BL/6 and SHP-knockout mice and performed RNA-sequencing analyses to identify genes regulated by SHP.

281 we performed integrative methylation and RNA-sequencing analyses to identify genes that were suppress

282 profiling and chromatin immunoprecipitation sequencing analyses unraveled a transcriptional reductio

283 ing retina, we performed high-throughput RNA sequencing analyses using the Rds/Prph2 (P216L) transgen

284 Using intra-IDL PCR and sequence analyses we also provide evidence that GPIDL is

285 RT-PCR) with gene-specific primers, and cDNA sequencing analyses we determined that the novel transcr

286 Using in silico genome-wide sequence analyses, we identified miR-495 as a miRNA whos

287 Based on structural, functional, and sequence analyses, we propose that the redox-sensitive A

288 Based on structural and sequence analyses, we propose that the transmembrane dom

289 Through single-cell RNA sequence analyses, we show that the lineage hierarchy of

290 etic and biochemical studies as well as deep sequencing analyses, we find that AGO mutations disrupti

291 Using microarray and deep-sequencing analyses, we found that galectin-7 positively

292 As assessed by ChIP-sequencing and RNA-sequencing analyses, we found that genes vital for osteo

293 By performing RNA- and exome-sequencing analyses, we report a novel fusion event, FGF

294 parative Ampliseq Comprehensive Cancer Panel sequence analyses were performed on DNA from unprocessed

295 Structure-guided and comparative sequence analyses were used to predict a network of amin

296 nical evaluations as well as exome and panel sequencing analyses were performed in affected and nonaf

297 Microbial 16S rRNA metagenomic sequencing analyses were then used to identify shifts in

298 As) is a crucial step in most homology-based sequence analyses, which constitute an integral part of

299 ACP mitogenome sequence analyses will facilitate ACP population researc

300 Subsequent RNA sequencing analyses yielded genome-wide transcriptome pr