ライフサイエンスコーパス: sequence similarity

1 ncertainty in fragment assignment because of sequence similarity.

2 ARC1 and MARC2, which share a high degree of sequence similarity.

3 gated K(+) (BK) channels despite the lack of sequence similarity.

4 hat are mostly unstructured and have minimal sequence similarity.

5 tif k-mers by smoothing sequence scores over sequence similarity.

6 ta(24-34) WT and hIAPP(19-29) S20G, with 64% sequence similarity.

7 ly diverged from one another and lack strong sequence similarity.

8 aterial packaged and the lack of significant sequence similarity.

9 be grouped into one of six clusters based on sequence similarity.

10 were clustered within networks generated by sequence similarity.

11 domains not correlated with the recombining sequence similarity.

12 inoderms that is searchable via keywords and sequence similarity.

13 betaherpesviruses, despite a lack of obvious sequence similarity.

14 assification that does not depend on protein sequence similarity.

15 are 70% identical in sequence and share 88% sequence similarity.

16 etween potential orthologous nodes with high sequence similarity.

17 wed 100% 16S rRNA, rpoB, sodA, and recN gene sequence similarity.

18 structural stability rather than amino acid sequence similarity.

19 e induced by different stresses and share no sequence similarity.

20 ack of significant capsid viral protein (VP) sequence similarity.

21 ion genes have been assigned based solely on sequence similarity.

22 database analyzed misclassification based on sequence similarity.

23 riocins from protein sequences without using sequence similarity.

24 identified and annotated to allergens using sequence similarity.

25 ental data and abundant primary sequence and sequence similarity.

26 ains hypothetical or only predicted based on sequence similarity.

27 pes in distant taxa may not be recognized by sequence similarity.

28 gs from different viral haplotypes with high sequence similarity.

29 res, which did not correlate with amino acid sequence similarities.

30 des with highest transport capacities shared sequence similarities.

31 immediately evident from the overall fold or sequence similarities.

32 ing to habitat, based on PPIs rather than on sequence similarities.

33 a novel direct ATF4 target gene, family with sequence similarity 129 member A (FAM129A), which is cri

34 g interacting protein (HHIP) and family with sequence similarity 13 member A (FAM13A) were shown to h

35 Genetic variation in the FAM13A (Family with Sequence Similarity 13 Member A) locus has been associat

36 th a distinct auxiliary subunit, family with sequence similarity 155 member A (FAM155A).

37 rticular disease and in FAM155A (family with sequence similarity 155A; rs67153654-A: P=3.0 x 10(-11),

38 determine the function of human family with sequence similarity 173 member B (FAM173B), a mitochondr

39 The human protein denoted "family with sequence similarity 173 member B" (FAM173B) was recently

40 Family with sequence similarity 19, member A1-5 (FAM19A1-A5; also kn

41 onditionally inactivated FAM20B (Family with sequence similarity 20 member-B), which is a newly ident

42 substantially phosphorylated by family with sequence similarity 20, member C (Fam20C), formerly know

43 Here, we demonstrate that family with sequence similarity 20C (Fam20C), a recently characteriz

44 One member, family with sequence similarity 20C (Fam20C), is the physiological G

45 gh reporter and ChIP assays that family with sequence similarity 213, member A (FAM213A), a peroxired

46 bsent in melanoma 2) and FAM26F (family with sequence similarity 26, member F).

47 The Family with Sequence Similarity 83 (FAM83) proteins are oncogenic, t

48 LRs from the Triticeae and displayed highest sequence similarity (89%) with a homolog of the Arabidop

49 Here, we identified family with sequence similarity 92, member A (FAM92A) and FAM92B, wh

50 three pseudosymmetric subdomains with shared sequence similarity, a feature not obvious from the init

51 ed structural motifs and show relatively low sequence similarity across different species, which make

52 ion (BMCSI), which first measures HA protein sequence similarities among influenza viruses (especiall

53 of a conserved functional domain and the low sequence similarity among experimentally characterized A

54 ppear to have driven a near complete loss of sequence similarity among modern tetherin genes and thei

55 Sequence similarity analysis shows a total of 3,220 uniq

56 ungal family GH26 endomannanases showed high sequence similarities and conserved binding residues, in

57 domain structures based on structure and/or sequence similarities and plays important roles in the s

58 We compared total sequence similarities and predicted binding strengths to

59 atrices such as Blosum62 are used to measure sequence similarities and to identify distant homologues

60 Existing methods depend on a clustering by sequence similarity and can be computationally slow.

61 3) and olive (Ole e 3, Ole e 8) showed high sequence similarity and cross-reacted with allergic pati

62 ad a common Zn(2+) bimetallo core but little sequence similarity and different auxiliary domains.

63 enomic analysis were used to investigate the sequence similarity and evolutionary relationships of th

64 We utilized sequence similarity and gene expression to categorize th

65 mbined approach that takes into account both sequence similarity and genome context.

66 guish viral haplotypes because of their high sequence similarity and heterogeneous sequencing coverag

67 f the flavivirus genus share a high level of sequence similarity and often circulate in the same geog

68 tion of local matches tend to confound local sequence similarity and overall protein homology and thu

69 Despite high protein sequence similarity and partially overlapping activity p

70 Additionally, sequence similarity and phylogenetic analysis demonstrat

71 present a novel tool, purge_dups, that uses sequence similarity and read depth to automatically iden

72 therin genes in various organisms exhibit no sequence similarity and share only a common architecture

73 revealed 2 distinct clades according to cas sequence similarity and spacer content.

74 s genes of the relevant A. thaliana genes by sequence similarity and synteny and sequenced candidate

75 adrenergic receptors (alpha2-ARs) based upon sequence similarity and the ability to interact with nor

76 nhibitor 1 (SPI-1) from Arabidopsis thaliana Sequence similarity and the shared beta-alpha-beta-beta-

77 ily interpretable methods for evaluating CDR sequence similarity and then clustering and classifying

78 ly reflect evolutionary distance measured by sequence similarity); and Variant groups (which largely

79 d sgl, mainly due to the small size, lack of sequence similarity, and embedded nature of these genes.

80 the O9a prototype, but they share only weak sequence similarity, and the putative binding pocket for

81 limitations of methods that rely solely upon sequence similarity are attracting increased attention.

82 Surprisingly, despite sequence similarity at the lateral packing interface, HE

83 The three homoeologous copies share 95-97% sequence similarity at the nucleotide, 98-99% amino acid

84 oded by segmentally duplicated genes of high sequence similarity (AtCGL20A and AtCGL20B).

85 However, existing methods define sequence similarity based on various heuristics and can

86 Combining sequence similarity-based matching and genetic features-

87 mplexity and high variance, which frustrates sequence similarity-based searches.

88 We confirmed the contribution of learning to sequence similarities between fathers and sons by experi

89 ing patterns of all aligned PPI networks and sequence similarities between their proteins.

90 o discovered that the extent and fidelity of sequence similarities between tutors and pupils were sig

91 rms in polyploid species because of the high sequence similarity between coexisting subgenomes.

92 allenge in studying the IGHV locus: the high sequence similarity between gene segments in different g

93 High sequence similarity between genomes in polyploids means

94 Our method calculates true sequence similarity between query sequences and database

95 Extensive hyperpolymorphism and sequence similarity between the HLA genes, however, pose

96 variable and correlated with the amino acid sequence similarity between the homologous gene products

97 Similar findings in humans and the sequence similarity between the human and baboon viruses

98 disease remains elusive, in part because low sequence similarity between the human and rodent H4 rece

99 tween species is governed in part by primary sequence similarity between the infectious prion aggrega

100 a has historically been difficult due to the sequence similarity between the polymorphic alleles.

101 Despite high sequence similarity between the RRs BceR and PsdR and th

102 Taking advantage of the high sequence similarity between the two transporters, we com

103 The MHM1 and MHM2, despite little sequence similarity between them, bear similar molecular

104 ombolitins displaying significant amino-acid-sequence similarity, BII and BL6, were assessed for anti

105 receptor (iGluR) superfamily on the basis of sequence similarity, but do not bind l-glutamate.

106 imal sacrifices in quality for tasks such as sequence similarity calculations.

107 Building upon the idea that sequence similarities can be easily displayed using grap

108 mers) have obvious structural homology while sequence similarity can be nonexistent.

109 We demonstrate that traditionally defined sequence similarity can be very low for pairs of sequenc

110 xamples, we also show how DNA-binding domain sequence similarity can yield confounding results as an

111 nd protein classification problems for which sequence similarity cannot be used.

112 suggesting that Bs3 and YUCs, despite their sequence similarity, catalyze distinct enzymatic reactio

113 esiding on different chromosomes and lacking sequence similarity, cCNV between these loci is strong,

114 Despite regions of high sequence similarity, CH1-CH2 domains can have remarkably

115 ously named folate receptor (FR) 4, based on sequence similarity considerations - triggers membrane a

116 y-pathway basis; codon usage, abundance, and sequence similarity contributed predictive power.

117 Networks that were reconciled with sequence similarity data and strongly enforced reversibi

118 However, sequence similarity does not always mean identical funct

119 In conclusion, sequence similarity does not necessarily result in struc

120 Our data show that sequence similarity does not translate to structural mim

121 Surprisingly, although little sequence similarity exists to known insecticidal protein

122 e correlation between functional similarity, sequence similarity, expression similarity and structura

123 Mutations in the Family with sequence similarity (FAM) 20 gene family are associated

124 ted best binning results between 97% and 94% sequence similarity for both DADA2-SSNs and SWARM-SSNs.

125 ify highly periodic repeats with significant sequence similarity, for which evolutionary rates and se

126 /5/10, AGO2/3/7 and AGO4/6/9, based on their sequence similarity, functional redundancy, as well as s

127 imilar sequences, including those with a low sequence similarity identified by a PSI-BLAST search.

128 s of ribosomal proteins (RPs) that show high sequence similarity/identity.

129 olactone display an unusually high degree of sequence similarity, implying that the few sites which v

130 MERS-CoV and SARS-CoV FP despite their high sequence similarity.IMPORTANCE Middle East respiratory s

131 ll for both easy targets (proteins with weak sequence similarity in PDB) and hard targets (proteins w

132 At 100% sequence similarity in SWARM-SSNs, NSC numbers decreased

133 background recombination caused by the high sequence similarity in the dimerization domains, we modi

134 erestingly, plant and animal TPCs share high sequence similarity in the filter region, yet exhibit dr

135 The high degree of sequence similarity in the flanking regions could often

136 ately affected by APA, primarily due to high sequence similarity in the motifs utilized by polyadenyl

137 gnment of short motifs, even if their mutual sequence similarity is only partial.

138 toformans NBRC 15712(T) (96.3% 16S rRNA gene sequence similarity) is the closest Bacillus species acc

139 Their high sequence similarity, low agonist selectivity, and lack o

140 nine methyltranserase termed BlArsM with low sequence similarities (</= 39%) to other ArsMs.

141 conclude that within a fairly broad range of sequence similarity, matching CDR3 sequences are likely

142 rity_matrix: an automated tool to generate a sequence similarity matrix from RNA-Seq data, which can

143 nucleotide k-mer frequency as the proxy for sequence similarity measurement.

144 lications, specifically in the estimation of sequence similarity measures to construct phylogenetic t

145 variants in or near the FAM13A (family with sequence similarity member 13A) GWAS locus associated wi

146 Recent studies have identified family with sequence similarity member 20C (FAM20C) as a kinase that

147 Family with sequence similarity member 20C is the primary but not th

148 By using HMM-HMM alignment as the sequence similarity metric, CMsearch clearly outperforms

149 By implementing a sequence similarity network (SSN) of the bCCP_MauG super

150 Through the use of a sequence similarity network (SSN), a number of sequences

151 Through sequence similarity network analyses, we identified 29 O

152 gap, we have used a highly scalable protein sequence similarity network analysis to delineate nearly

153 By combining sequence similarity network and phylogenetic analyses of

154 results of a bioinformatics analysis using a sequence similarity network revealed that phage Fds are

155 ing protein function, Effusion, which uses a sequence similarity network to add context for homology

156 across the entire superfamily and computed a sequence similarity network to guide classification into

157 The sequence similarity network workflow used here, SSNpipe,

158 Using a dataset of 9192 sequences, a sequence similarity network, and subsequently, a genome

159 Ancestral phylogenetic reconstruction and sequence similarity networking of enzymes from these clu

160 iversity and molecular diversity, we applied sequence similarity networks (SSNs) for second-level seq

161 Sequence similarity networks and genome neighborhood net

162 Using sequence similarity networks and genome neighborhood net

163 identified eight candidate catabolic genes, sequence similarity networks, and genome neighborhood ne

164 ved public sequences were central within TCR sequence-similarity networks.

165 In silico analysis reveals sequence similarities of GDAP1 to glutathione S-transfer

166 its wild type and a nonlinear dependence on sequence similarity of neoantigens to known antigens.

167 Due to the sequence similarity of several genes on the megaplasmid,

168 However, the level of sequence similarity of TCR repertoires within and betwee

169 sterior probability based upon the degree of sequence similarity of the database hit to the query seq

170 This cross-reactivity is explained by the sequence similarity of the two viruses, as the ZIKV pept

171 Given the high sequence similarity of these paired viral epitopes (56 a

172 Despite a sequence similarity of ~96%, PtAADC1 and PtAAS1 showed d

173 Fs, a screening is performed by checking for sequence similarity or presence in active transcripts of

174 have inferred orthology based either on pure sequence similarity or using gene-tree approaches.

175 Despite having low sequence similarity, portal structures across bacterioph

176 d evaluate multiple lines of evidence (e.g., sequence similarity, RNA sequencing [RNA-Seq] results, g

177 wn that this matrix can be optimized so that sequence similarity scores correlate well with structure

178 mited by the intrinsic limitations of common sequence similarity searches and available databases.

179 sed open source software suite for sensitive sequence similarity searches and protein fold recognitio

180 ons between PAS and known PRC2 subunits, and sequence similarity searches demonstrated that PAS is no

181 BLAST provides sequence similarity searches of GenBank and other sequen

182 es can be discovered by methods going beyond sequence similarity searches to integrate multiple pathw

183 ysis of the proteins, further confirmed that sequence similarity searches using our profiles could su

184 Using sequence similarity searches, we have identified 257 new

185 that might account for systematic errors in sequence similarity searches.

186 ssitate quality control, genome assembly and sequence similarity searching before an isolate's ST can

187 s can also be searched by a customized BLAST sequence similarity searching program.

188 analyses demonstrate that this same range of sequence similarity strikes a favorable specificity/sens

189 ngly, these Zap proteins show no discernable sequence similarity, suggesting that they likely harbor

190 Based on their sequence similarity, terpene synthases from land plants

191 -2/4-binding activity, an assertion based on sequence similarity that TSP-1 shares with the von Wille

192 Despite having high structural and sequence similarities, the two enzymes are functionally

193 Despite sequence similarities, their allergenicity varies greatl

194 While the stems of SL1 and SLC share little sequence similarity, their end loops are of the same siz

195 On the basis of sequence similarity, these are frequently classified int

196 rforming independent tests, with the varying sequence similarity thresholds of 0.8, 0.7, 0.6 and 0.5,

197 the complete and partial genomes showing no sequence similarities to public databases.

198 demonstrate its remarkable architectural and sequence similarities to spider silk fibroins, indicatin

199 chment shared 98.6%, and 98.5% 16S rRNA gene sequence similarities to Sulfurospirillum multivorans.

200 process and its possible origin in light of sequence similarities to that region in other mouse geno

201 s molecules involved in such death show some sequence similarities to those involved in apoptosis, le

202 novo, and contigs with predicted amino acid sequence similarities to viruses in the nonredundant pro

203 L encodes a protein of unknown function with sequence similarity to 4-hydroxyphenylpyruvate dioxygena

204 drolase family 9 (GH9) catalytic domain with sequence similarity to a gene from Coprococcus eutactus

205 d mitochondrial sequences, but instead using sequence similarity to a large database of publicly avai

206 unique tandem repeat domain that shares high sequence similarity to a non-syntenic zebrafish analog,

207 present a split gene pair, where Rv0891c has sequence similarity to adenylyl cyclases, and Rv0890c ha

208 activity, whereas the C-terminal domain has sequence similarity to an FMN-dependent family of nitror

209 ntain lineage-specific genes that exhibit no sequence similarity to any genes outside the lineage.

210 Because of its sequence similarity to Bax and Bak, Bok has long been co

211 found in all genomes, some of which display sequence similarity to certain viruses.

212 transporters as templates but these have low sequence similarity to CFTR and are not ion channels.

213 terminal domain in HgGLAND18 contains unique sequence similarity to domains of an immunosuppressive e

214 ones, even when those phages exhibit little sequence similarity to established phage families.

215 ated from Leptospira licerasiae-which shares sequence similarity to eukaryotic CNG and HCN channels-i

216 Sequence similarity to genes characterized in previous s

217 ate genes for these traits in pigeonpea have sequence similarity to genes functionally characterized

218 ith predicted transmembrane domains and high sequence similarity to glutathione reductase (GR) was im

219 st Tsr1 is a ribosome biogenesis factor with sequence similarity to GTPases, which is essential for c

220 d to be a 40-amino acid peptide showing high sequence similarity to human (93%), mouse (93%), and Xen

221 Mth-EphA displays high sequence similarity to its orthologue from M. tuberculos

222 transformation at DNA sites with increasing sequence similarity to its target.

223 st of the existing detection methods rely on sequence similarity to known bacteriophage sequences, im

224 m mature or imbibed cucumber seeds with high sequence similarity to known GA 3-oxidases.

225 While this GEF bears no obvious sequence similarity to known GEFs, crystal structures of

226 unresolved because both Izumo1 and Juno lack sequence similarity to known membrane fusogens.

227 one of our nanostructures showed significant sequence similarity to known pH-sensitive motifs, sugges

228 e-art statistical method to quantify a CRM's sequence similarity to many different training sets of C

229 es (e.g., coelacanths) does tetherin exhibit sequence similarity to one potential sister gene.

230 ational taxonomic units showed the strongest sequence similarity to Ophiocordyceps, Verticillium, Pse

231 The 9,174-nt-long genome showed limited sequence similarity to other known viruses.

232 of 889 bp, over 90% of which has significant sequence similarity to other legumes.

233 The transmembrane subunit, MlaE, has minimal sequence similarity to other transporters, and the struc

234 ealed that the acyltransferase slr2103, with sequence similarity to plant esterase/lipase/thioesteras

235 fied peptides cluster products, reporting of sequence similarity to proteins encoded in experimentall

236 r role of CelTOS is unknown because it lacks sequence similarity to proteins of known function.

237 by ORF CT009 interacts with MreB despite low sequence similarity to RodZ.

238 ORF CT588 has a strong sequence similarity to RsbU cytoplasmic phosphatase doma

239 ion no. KY000533; 1367 bp) showed only 96.2% sequence similarity to S. malaysiensis and exhibited min

240 Given its sequence similarity to SARS-CoV, as well as related coro

241 This includes SARS-CoV, which has high sequence similarity to SARS-CoV-2 and is the best-charac

242 yet to be considered: in the absence of any sequence similarity to the binding motif, can DNA shape

243 With over 65% sequence similarity to the chicken Nr-13, herpesvirus of

244 ein-coupled apelin receptor, despite lack of sequence similarity to the established ligand apelin.

245 a conserved region in Dsup proteins exhibits sequence similarity to the nucleosome-binding domain of

246 s of viral proteins that have no and distant sequence similarity to the ones used for training, recep

247 -linked non-coding genomic repeats that have sequence similarity to the protein-coding host gene vasa

248 nd in almost all eubacteria and plants, with sequence similarity to the RecA strand exchange protein

249 onspecific mutation occurring at a site with sequence similarity to the targeted edit region.

250 ike fold, with no functional, structural, or sequence similarity to their bacterial counterparts.

251 spite the lack of significant topological or sequence similarity to their natural granulopoietic coun

252 innexins, and LRRC8, pannexins have minimal sequence similarity to these protein families.

253 tRNA, based on its association with TEP1 and sequence similarity to those of other known and predicte

254 These transcripts include some examples with sequence similarity to transposable elements and other s

255 lusive to the Y in all species examined, yet sequence similarity to YG2 is not detectable in the geno

256 clustered group of receptors that share core sequence similarities, together with a dispersed set of

257 istance, these proteins share structural and sequence similarities, underscoring their importance acr

258 Remote sequence similarity was identified between the plant pat

259 bacterium Lactococcus lactis On the basis of sequence similarities, we first identified three gene pa

260 me Annotation Pipeline (PGAP) relies more on sequence similarity when confident comparative data are

261 thologs in different species despite limited sequence similarity, which is applicable to mammalian an

262 y, some proteins specific to Lh VLPs possess sequence similarities with bacterial secretion system pr

263 t gamma-clade HD-Zip I TFs share significant sequence similarities with homologous genes from other p

264 to the RPamide neuropeptide family and share sequence similarities with neuropeptides of the bilateri

265 Sequence similarities with tropomyosin and myosin from m

266 reading frames, the majority of which share sequence similarity with a virus infecting the black tig

267 AD family, AAD3 shares the highest degree of sequence similarity with AAD2 and AAD4.

268 sid, which we have named AAVv66, shares high sequence similarity with AAV2.

269 d polypeptide (IAPP), a peptide which shares sequence similarity with Abeta.

270 carotene desaturase proteins did not display sequence similarity with allergens or toxins.

271 d on cassava whole-genome sequence and their sequence similarity with Arabidopsis TCPs.

272 putatively secreted proteins shared highest sequence similarity with archaeal and fungal enzymes, wh

273 to Bacteria, of which 12% shared the highest sequence similarity with candidate phyla (10,11) .

274 Mouse HOX1 proteins display low (30%) sequence similarity with Drosophila Labial.

275 both twins and their siblings had more vocal sequence similarity with each other than with non-siblin

276 Many of these effectors share structural and sequence similarity with eukaryotic proteins.

277 Although FLNb shows high amino acid sequence similarity with FLNa, we reveal that only FLNa,

278 Contrary to the common approach of using sequence similarity with hsp/hsc70 of a wide spectrum of

279 be unique to Gram-positive cocci and has no sequence similarity with known transcriptional activator

280 s BAFF-like gene in lampreys exhibits higher sequence similarity with mammalian BAFF than APRIL.

281 II RubisCOs were recovered which share high sequence similarity with metagenomic scaffolds from uncu

282 BCL-3 that interacts with p50 and shares low sequence similarity with other IkappaB proteins.

283 in cardiac muscle with high catalytic domain sequence similarity with other MLCKs but lacking an auto

284 However, TNT lacks sequence similarity with other NAD(+) hydrolyzing enzyme

285 ToPI1 shares no sequence similarity with other PIs characterized to date

286 The PmMDV proteins have no significant sequence similarity with other PVs, except for an SF3 he

287 MnxG shares sequence similarity with other, structurally characteriz

288 sults indicate that, although SynDIG4 shares sequence similarity with SynDIG1, it might act through a

289 nispryn, encoded by Fsd2, that has extensive sequence similarity with the C-terminus of myospryn.

290 erestingly, an internal region of Mcc shares sequence similarity with the central domain of the prion

291 ized chimera of a snail AChBP, which has 71% sequence similarity with the extracellular ligand-bindin

292 The emergent H5N6 viruses, which share high sequence similarity with the human isolate A/Guangzhou/3

293 tantial proportion of the genes that exhibit sequence similarity with the mutated gene's mRNA, sugges

294 Interestingly, BsPdaC shares higher sequence similarity with the peptidoglycan GlcNAc deacet

295 re significantly shorter and share almost no sequence similarity with the S. cerevisiae homolog.

296 N pathway, but surprisingly, they exhibit no sequence similarity with their RSV equivalents.

297 ase A paralogs, but the toxin does not share sequence similarity with these nucleases and lacks the c

298 Lastly, some isolates found on peony share sequence similarity with unnamed species found living as

299 RIFMO shares moderate sequence similarity with well characterized flavoprotein

300 re categorized into related classes based on sequence similarity, with members of the class 5 fimbria