ライフサイエンスコーパス: serine-threonine phosphatase

1 e structure-function studies of this protein serine/threonine phosphatase.

2 phatase 4 (PP4; also called PPX and PPP4), a serine/threonine phosphatase.

3 ciates with protein phosphatase 2A (PP2A), a serine/threonine phosphatase.

4 38 kDa catalytic subunit of a type 1 protein serine/threonine phosphatase.

5 but not the activity of PP2A, another major serine/threonine phosphatase.

6 ms, controls a serine/threonine kinase and a serine/threonine phosphatase.

7 of a novel PKC isozyme and a bFGF-dependent serine/threonine phosphatase.

8 , a cyclosporin-sensitive, calcium-regulated serine/threonine phosphatase.

9 (PP2A) is a highly conserved and ubiquitous serine/threonine phosphatase.

10 own about the expression and function of the serine-threonine phosphatases.

11 2A (PP2A), an abundantly expressed family of serine-threonine phosphatases.

12 gement during platelet aggregation activates serine/threonine phosphatases.

13 rity to members of the PP2C class of protein serine/threonine phosphatases.

14 e 2A (PP2A) is a member of the intracellular serine/threonine phosphatases.

15 associate with members of the PP2A family of serine/threonine phosphatases.

16 ytes with calyculin A, a potent inhibitor of serine/threonine phosphatases.

17 lls, BAD was rapidly dephosphorylated by the serine-threonine phosphatase 1 alpha, and localized in t

18 orylation of mitotic FAK in vitro by protein serine/threonine phosphatase 1 restores the ability of F

19 cluding of heat shock protein 90 and protein serine/threonine phosphatase 1-alpha.

20 Notably, genetic disruption of protein serine/threonine phosphatase-1 (PP1) and its regulator N

21 protein that regulates functions of protein serine/threonine phosphatase-1 in cell proliferation and

22 ro and in vivo evidence to show that protein serine/threonine phosphatase-1 is a major phosphatase th

23 ctase active site is highly conserved in the serine/threonine phosphatase-1 subfamily, but not in the

24 CCC: PPP2R1A encodes a regulatory subunit of serine/threonine phosphatase 2, and ARID1A encodes adeni

25 toichiometric complex of CaMKIV with protein serine-threonine phosphatase 2A (PP2A) was identified in

26 at the protein HOX11 interacted with protein serine-threonine phosphatase 2A catalytic subunit (PP2AC

27 Protein serine/threonine phosphatase 2A (PP2A) activity must be

28 tro mixing experiments indicate that protein serine/threonine phosphatase 2A (PP2A) can dephosphoryla

29 vidence indicates that regulation of protein-serine/threonine phosphatase 2A (PP2A) involves its asso

30 Protein serine/threonine phosphatase 2A (PP2A) is a critical reg

31 Protein serine/threonine phosphatase 2A (PP2A) is a multifunctio

32 Protein serine/threonine phosphatase 2A (PP2A) regulates a wide

33 many kinase cascades, heterotrimeric protein serine/threonine phosphatase 2A (PP2A), is composed of c

34 V was shown to stably associate with protein serine/threonine phosphatase 2A (PP2A), which was propos

35 by several kinases and inhibited by protein serine/threonine phosphatase 2A (PP2A).

36 y, we show that polyamine depletion inhibits serine/threonine phosphatase 2A (PP2A).

37 downstream repressor COUP-TFII by inhibiting serine/threonine phosphatase 2A activity, and that decre

38 sein kinase 2 activity and increased protein serine/threonine phosphatase 2A activity, resulting in a

39 chanisms control the activity of the protein serine/threonine phosphatase 2A catalytic subunit (PP2Ac

40 Casein kinase 2 catalyzed protein serine/threonine phosphatase 2A phosphorylation thereby

41 ed by casein kinase 2 complexed with protein serine/threonine phosphatase 2A.

42 eraction between casein kinase 2 and protein serine/threonine phosphatase 2A.

43 easing Sp1 binding via the action of protein serine/threonine phosphatase 2A.

44 wn that EGCG can negatively regulate protein serine/threonine phosphatase-2A (PP-2A) to positively re

45 nine phosphatase-1 subfamily, but not in the serine/threonine phosphatase-2A or -2B subfamilies.

46 The catalytic subunit of protein serine/threonine phosphatase 4 (PP4C) has greater than 6

47 lytic and regulatory subunits of the protein serine/threonine phosphatase 4 complex (PP4c/PP4R1).

48 irect regulatory linkage between the protein serine-threonine phosphatase 5 (PP5) and ATM.

49 Serine/threonine phosphatase 5 (PP5) can act as a suppre

50 , including purple acid phosphatase, protein serine/threonine phosphatases, 5'-nucleotidase, and DNA

51 noprecipitated c-Fos protein with the type 2 serine/threonine phosphatase A (PP2A) and immunoblotting

52 nd treatment with either protein tyrosine or serine/threonine phosphatases abolished its activity.

53 to TFEB dephosphorylation through endogenous serine/threonine phosphatase action.

54 Serine-threonine phosphatase activity dephosphorylated B

55 ediated by KCC2 is completely independent of serine-threonine phosphatase activity, suggesting that t

56 d FIN13 expressed in mammalian cells exhibit serine-threonine phosphatase activity, which requires Mn

57 nuclei-free cell lysates, we find increased serine/threonine phosphatase activity associated with Go

58 HOX11 also inhibited PP2A serine/threonine phosphatase activity concomitant with s

59 ubiquitination of proteins, we examined the serine/threonine phosphatase activity in our CAOV3 cells

60 y has been shown to have modest tyrosine and serine/threonine phosphatase activity, we find that it i

61 llular mechanism whereby Ca(2+) can activate serine/threonine phosphatase activity.

62 osphorylated c-Jun, and by the inhibition of serine/threonine phosphatase activity.

63 -terminal kinase activity but to a decreased serine/threonine phosphatase activity.

64 ts lacking PP1cgamma, a catalytic subunit of serine/threonine phosphatase, alpha(IIb)beta3 failed to

65 Inhibition of serine/threonine phosphatases also enhanced sickle eryth

66 Interestingly, okadaic acid, an inhibitor of serine/threonine phosphatase, also strongly activated tr

67 Loss of the PrpC serine-threonine phosphatase and the associated PrkC kin

68 h repeat protein phosphatase 1) is a protein-serine/threonine phosphatase and a negative regulator of

69 the protein phosphatase 2A (PP2A) family of serine-threonine phosphatases, and this interaction is r

70 ein kinase C (PKC) activation, inhibition of serine/threonine phosphatase, and an active protein tyro

71 in phosphatase-2A (PP2A), a widely expressed serine/threonine phosphatase, and the heterotrimeric G p

72 activating several tyrosine phosphatases and serine/threonine phosphatases, and it suppresses the cel

73 hod is applicable to other DUSPs and protein-serine/threonine phosphatases, and the substrate specifi

74 Protein serine-threonine phosphatases are assembled from catalyt

75 All of the known protein serine/threonine phosphatases are expressed in the brain

76 The activity and specificity of serine/threonine phosphatases are governed largely by th

77 Members of the PP2A family of serine/threonine phosphatases are important human tumor

78 of the phosphoprotein phosphatase family of serine/threonine phosphatases are thought to exist in di

79 s (PLMs), potent and selective inhibitors of serine threonine phosphatases, are of interest for their

80 tein phosphatase-1 (PP1), a major eukaryotic serine/threonine phosphatase, are defined by the associa

81 In this review, we present protein serine/threonine phosphatases as viable therapeutic targ

82 thelial cells, we identify PP2A as the first serine/threonine phosphatase associated with the multipr

83 in phosphatase 4 (PP4), a novel PP2A-related serine/threonine phosphatase, at a 50% inhibitory concen

84 we examined the regulatory interactions of a serine/threonine phosphatase (BA-Stp1), serine/threonine

85 gly, has the sequence hallmarks of a phospho-serine/threonine phosphatase belonging to the PPP family

86 cancer cells, it was determined that PP2A, a serine/threonine phosphatase, binds and dephosphorylates

87 n synthase kinase-3-like kinase (BIN2) and a serine/threonine phosphatase (BSU1).

88 The serine-threonine phosphatase calcineurin (Cn)A plays a c

89 es a G(1) cell cycle arrest, implicating the serine/threonine phosphatase calcineurin as one Ca(2+)/C

90 (slc4a7) and the Ca(2+)/calmodulin-activated serine/threonine phosphatase calcineurin exist and play

91 The serine/threonine phosphatase calcineurin is an important

92 ies have revealed that the calcium-dependent serine/threonine phosphatase calcineurin mediates the ef

93 g infection is modulated by Ca(2+)-dependent serine/threonine phosphatase calcineurin, an important t

94 order to explore the redox regulation of the serine/threonine phosphatase calcineurin, we have invest

95 activity of the calcium/calmodulin-dependent serine/threonine phosphatase calcineurin.

96 s dephosphorylation by the calcium-dependent serine/threonine phosphatase calcineurin.

97 ium signals regulate MEF2 activity through a serine/threonine phosphatase calcineurin.

98 porin A, an immunosuppressant inhibiting the serine/threonine phosphatase calcineurin.

99 NFI phosphorylation are all modulated by the serine/threonine phosphatase calcineurin.

100 dual specificity phosphatase (cdc25b), and a serine/threonine phosphatase (calcineurin).

101 uct was discovered to be an inhibitor of the serine/threonine phosphatase, calcineurin, and its signa

102 dk4 and the calcium and calmodulin activated serine/threonine phosphatase, calcineurin.

103 idues, and treatment of cRaf-1 with protein (serine/threonine) phosphatases can deactivate it, at lea

104 Treatment of CKIepsilon with any of several serine/threonine phosphatases causes a marked increase i

105 PP2A-B56 is a serine/threonine phosphatase complex that regulates seve

106 ase 2A (PP2A) is a family of multifunctional serine/threonine phosphatases consisting of a catalytic

107 tase 2A (PP2A) is an abundant heterotrimeric serine/threonine phosphatase containing highly conserved

108 a activation and PDZ-mediated formation of a serine/threonine phosphatase-containing complex by synde

109 esting in view of literature suggesting that serine/threonine phosphatases could be subject to redox

110 The protein serine/threonine phosphatase designated PP5 has little b

111 rotein phosphatases, including the family of serine/threonine phosphatases designated PP2A, is essent

112 Inhibition of serine/threonine phosphatases did not affect the activit

113 ole for the dephosphorylation events via the serine/threonine phosphatases during the integrin outsid

114 Unlike kinases, it remains unclear how serine/threonine phosphatases engage the signaling netwo

115 A) is a ubiquitously expressed member of the serine-threonine phosphatase family that is involved in

116 otein kinases Cdk7 and Cdk9, whereas protein serine/threonine phosphatase FCP1 dephosphorylates CTD.

117 We have identified a novel type 2C serine-threonine phosphatase, FIN13, whose expression is

118 Surprisingly, this structure revealed a serine/threonine phosphatase fold that unexpectedly targ

119 is a homologue of the PPM family of protein-serine/threonine phosphatases found in all eukaryotes as

120 in phosphatase 2A (PP2A) is one of the major serine/threonine phosphatases found in eukaryotic cells.

121 tural gene for a putative PPP family protein-serine/threonine phosphatase from the microcystin-produc

122 frames (ORFs) encoding two potential protein-serine/threonine phosphatases from the cyanobacterium Sy

123 A putative protein serine/threonine phosphatase gene has been isolated from

124 determinant for the targeting of the type 1 serine/threonine phosphatase (Glc7) to the bud neck.

125 protein phosphatase X (PPX)), a PP2A-related serine/threonine phosphatase, has been shown to be invol

126 Ptc1p, a serine/threonine phosphatase, has previously been shown

127 Okadaic acid-sensitive serine/threonine phosphatases have been shown to regulat

128 Here we provide evidence that ppm-1, a serine/threonine phosphatase homologous to human PP2Calp

129 The inhibition of serine/threonine phosphatases, however, has no effect on

130 otein phosphatase 2A (PP2A), one of the main serine-threonine phosphatases in mammalian cells, mainta

131 Protein phosphatase 2A (PP2A), the major serine/threonine phosphatase in eukaryotic cells, is a h

132 ion C (rdgC) gene encodes an unusual protein serine/threonine phosphatase in that it contains at leas

133 PTC1 encodes a serine/threonine phosphatase in the high-osmolarity glyc

134 ence for the involvement of a type 1 protein serine/threonine phosphatase in the ultraviolet radiatio

135 In this review, we concentrate on serine/threonine phosphatases in apicomplexan parasites,

136 h RNA interference (RNAi)-based screening of serine/threonine phosphatases in Drosophila S2 cells, we

137 impaired distribution and lower activity of serine/threonine phosphatases in the context of HIV infe

138 impaired distribution and lower activity of serine/threonine phosphatases in the context of HIV infe

139 ed activity of calcineurin, a Ca2+-dependent serine/threonine phosphatase, increases synaptic express

140 ons show that LTD expression is increased by serine/threonine phosphatase inhibition, and negatively

141 The serine-threonine phosphatase inhibitor (OA) decreased NO

142 e required for iNOS transcription, while the serine-threonine phosphatase inhibitor (OA) had no effec

143 nadate [PV], phenylarsine oxide [PAO]) and a serine-threonine phosphatase inhibitor (okadaic acid [OA

144 inocytes, the tumor promoter okadaic acid, a serine-threonine phosphatase inhibitor, increased bindin

145 ras and KCC2 is completely resistant to this serine-threonine phosphatase inhibitor.

146 in, prostaglandin E(2), cAMP-raising agents, serine/threonine phosphatase inhibitor and activation of

147 The serine/threonine phosphatase inhibitor calyculin A (5 nM

148 ate, the Ca(2+) ionophore ionomycin, and the serine/threonine phosphatase inhibitor calyculin A incre

149 We show that the serine/threonine phosphatase inhibitor calyculin A induc

150 hibitors citrate and tartrate or the protein serine/threonine phosphatase inhibitor okadaic acid.

151 stimulated by treatment with calyculin A, a serine/threonine phosphatase inhibitor that elevates MLC

152 protein kinases A and C, and okadaic acid (a serine/threonine phosphatase inhibitor) decreased the cu

153 beta(3)-fibrinogen blocker) or okadaic acid (serine/threonine phosphatase inhibitor) dramatically enh

154 reatment of eosinophils with okadaic acid, a serine/threonine phosphatase inhibitor, at the concentra

155 nduction by nickel; however, okadaic acid, a serine/threonine phosphatase inhibitor, induced Cap43 to

156 When cells were lysed in the presence of serine/threonine phosphatase inhibitor, NaF, the PKA-enh

157 cells were treated with okadaic acid (OA), a serine/threonine phosphatase inhibitor, to induce tau ph

158 cose transport stimulated by okadaic acid, a serine/threonine phosphatase inhibitor, was also 45% low

159 The addition of the serine/threonine phosphatase inhibitors calyculin A and

160 nd ex vivo skin and esophagus cultures, with serine/threonine phosphatase inhibitors causes a dramati

161 nt cell cytosol, is resistant to the classic serine/threonine phosphatase inhibitors okadaic acid and

162 Treatment of cells with the cell-permeable serine/threonine phosphatase inhibitors okadaic acid or

163 d channel activation are inhibited by type 1 serine/threonine phosphatase inhibitors.

164 , an inhibitor of type 1 and type 2A protein serine/threonine phosphatase, inhibits both receptor-ind

165 nd phosphatases modulate GPCR signaling, how serine/threonine phosphatases integrate with G protein s

166 vel cytoskeletal associated protein, proline serine threonine phosphatase interacting protein (PST PI

167 s resulted in the identification of proline, serine, threonine phosphatase interacting protein (PSTPI

168 quence similarity with the PST PIP (proline, serine, threonine phosphatase interacting protein)/CDC15

169 CD2BP1 and its murine ortholog, proline-serine-threonine phosphatase interacting protein (PSTPIP

170 c15 homology family protein PSTPIP2 (proline-serine-threonine phosphatase interacting protein 2), spo

171 ted an interaction between pyrin and proline serine threonine phosphatase-interacting protein 1 (PSTP

172 ression of the F-BAR domain protein, proline serine threonine phosphatase-interacting protein 2 (PSTP

173 We now show that proline serine threonine phosphatase-interacting protein [PSTPIP

174 Mutations in the gene encoding proline serine threonine phosphatase-interacting protein-1 (PSTP

175 f a cytoskeletal-associated protein, proline-serine-threonine phosphatase-interacting protein (PSTPIP

176 h dominant missense mutations in the proline-serine-threonine phosphatase-interacting protein 1 gene

177 Proline-serine-threonine phosphatase-interacting protein 1-assoc

178 d may be a curative option for other proline-serine-threonine phosphatase-interacting protein 1-assoc

179 ich carry a missense mutation in the proline-serine-threonine phosphatase-interacting protein 2 (Pstp

180 Missense mutation in the proline-serine-threonine phosphatase-interacting protein 2 (Pstp

181 pressions of anti-inflammatory IL37, proline-serine-threonine phosphatase-interacting protein 2 (PSTP

182 Missense mutation (L98P) of proline-serine-threonine phosphatase-interacting protein 2 (Pstp

183 The mouse Lupo (I282N) mutation in proline-serine-threonine phosphatase-interacting protein 2 (PSTP

184 in phosphatase 2A (PP2A) is a heterotrimeric serine/threonine phosphatase involved in essential cellu

185 tein phosphatase-2A (PP2A) is a multisubunit serine/threonine phosphatase involved in intracellular s

186 of protein phosphatase 2A, a family of major serine/threonine phosphatases involved in regulating cel

187 The multifunctional activity of many serine/threonine phosphatases is achieved through their

188 Calcineurin, a serine-threonine phosphatase, is activated by calcium an

189 at protein phosphatase 1 (PP1), a ubiquitous serine/threonine phosphatase, is a novel potent positive

190 phatase 2A (PP2A) is an essential eukaryotic serine/threonine phosphatase known to play important rol

191 urface receptors such as CTLA-4 and CD28 and serine/threonine phosphatases may represent a novel mech

192 erevisiae, we isolated PTC2, which encodes a serine/threonine phosphatase of type 2C.

193 Addition of the inhibitor-of-protein serine/threonine phosphatases, okadaic acid, blocks the

194 Affinity isolation of protein serine/threonine phosphatases on the immobilized phospha

195 to be calcineurin because inhibitors of this serine/threonine phosphatase partially rescue the block

196 tion of IRS1 and increased expression of the serine/threonine phosphatase Phlpp1.

197 nd that PPM1A, a metal ion-dependent protein serine/threonine phosphatase, physically interacts with

198 data suggest that the PPEF family of protein serine/threonine phosphatases plays a specific and conse

199 okine-induced activation of NF-kappaB, while serine-threonine phosphatases posttranscriptionally regu

200 Protein serine/threonine phosphatase (PP) 2A is a ubiquitous enz

201 h correlated with inhibition of the major Rb serine/threonine phosphatase PP1.

202 Serine/threonine phosphatases PP1 and PP2A, which are cl

203 oM did not significantly inhibit the protein serine/threonine phosphatases PP1 and PP2A.

204 (PKA)-activated inhibitor of type 1 protein serine/threonine phosphatase (PP1), in a yeast two-hybri

205 the factor that activates the type 1 protein serine/threonine phosphatase (PP1), which dephosphorylat

206 Type-1 protein serine/threonine phosphatases (PP1) are uniquely inhibit

207 r-2 (I-2) selectively inhibit type 1 protein serine/threonine phosphatases (PP1).

208 ed roles of highly expressed skeletal muscle serine/threonine phosphatases (PP1, PP2A, PP2B, and PP2C

209 reciprocal regulation of two major mammalian serine/threonine phosphatases, PP1 and PP2A.

210 ists in stable and active complexes with the serine/threonine phosphatases PP1beta and PP1gamma, enzy

211 n, interacts with HDAC1, HDAC2, and with the serine-threonine phosphatase PP1CC.

212 Inhibition of the serine/threonine phosphatase, PP2-A, with okadaic acid r

213 previously unrecognized requirement for the serine-threonine phosphatase PP2A in the function of T(r

214 Alterations involving serine-threonine phosphatase PP2A subunits occur in a ra

215 NF-alpha was due, in part, to an increase in serine/threonine phosphatase PP2A activity.

216 Furthermore, we found that the serine/threonine phosphatase PP2A also regulates FoxO3a.

217 to be due to the combined activities of the serine/threonine phosphatase PP2A and the tyrosine phosp

218 We find that the serine/threonine phosphatase PP2A can physically associa

219 PTPPBS family of tyrosine phosphatases, the serine/threonine phosphatase PP2A, and cholesterol.

220 cific phosphatase activity that contains the serine/threonine phosphatase PP2A, the tyrosine phosphat

221 gration is mediated by the activation of the serine/threonine phosphatase PP2A.

222 nction is dependent upon the activity of the serine/threonine phosphatase PP2A.

223 c acid, an inhibitor of the major PPP family serine/threonine phosphatases PP2A and protein phosphata

224 is regulated by a tightly associated protein serine-threonine phosphatase (PP2A).

225 suppressed by SCF through phosphorylation of serine/threonine phosphatase (PP2A) and correlated well

226 to be mediated, in part, by type 2A protein serine/threonine phosphatases (PP2A).

227 o-purified with the main two subunits of the serine/threonine phosphatase, PP2A.

228 mised in a strain lacking functional type 2C serine/threonine phosphatases (PP2C), Ptc1 and Ptc3.

229 Two serine/threonine phosphatases, PP2Calpha and PP2A, were

230 esent physiological evidence for the protein serine/threonine phosphatase, PP5, as an effector of Rac

231 The serine/threonine phosphatase PPM1D/Wip1 inactivates p53

232 Here we show that the oncogenic p53-induced serine/threonine phosphatase, PPM1D (or Wip1), dephospho

233 We now identify a potential role for the serine-threonine phosphatase PPM1G in translational regu

234 Selective inhibitors for each serine/threonine phosphatase (PPP) are essential to inve

235 reen that identifies the PP2A heterotrimeric serine/threonine phosphatases PPP2R2A, PPP2R2D, PPP2R5A,

236 d after conserved regions within the protein-serine/threonine phosphatases (PPs) of the PP1/2A/2B sup

237 rential regulation of okadaic acid-sensitive serine/threonine phosphatases; presumably, these phospha

238 ated at the post-translational level, by the serine-threonine phosphatase protein phosphatase 2A (PP2

239 f oncogenes or the disruption of the general serine-threonine phosphatase protein phosphatase 2A (PP2

240 The serine/threonine phosphatase protein phosphatase 2A (PP2

241 The serine/threonine phosphatase protein phosphatase 5 (PP5)

242 2Ralpha) and gamma chain and also endogenous serine/threonine phosphatase protein phosphates 1 and/or

243 Inhibition of tyrosine phosphatases and serine/threonine phosphatases protein phosphatase 1 (PP1

244 nomic approach, we have identified a protein serine/threonine phosphatase, protein phosphatase 2A (PP

245 Knockdown of Nqo1 enhanced activity of the serine/threonine phosphatase, protein phosphatase 2A, wh

246 e was also inactivated by treatment with the serine/threonine phosphatase, protein phosphatase 2A; ok

247 ases in Mycobacterium tuberculosis, only one serine/threonine phosphatase, PstP, has been identified.

248 ment of SH2-B with protein phosphatase 2A, a serine/threonine phosphatase, reduces the many forms to

249 Elucidating how serine/threonine phosphatases regulate kinase function a

250 A1AT, protein phosphatase 2A (PP2A), a major serine-threonine phosphatase, regulates similar biologic

251 Protein phosphatase 1 (PP1) is a ubiquitous serine/threonine phosphatase regulating many cellular pr

252 osphatase I (PP1) is an essential eukaryotic serine/threonine phosphatase required for many cellular

253 ephosphorylation pathway mediated by PKC and serine/threonine phosphatase(s).

254 s appear to be mediated by the activation of serine-threonine phosphatase, since they are blocked by

255 d sodium molybdate) but not by inhibitors of serine/threonine phosphatases (sodium fluoride, okadaic

256 es), the precise role of the co-transcribing serine/threonine phosphatase (SP-STP) has remained enigm

257 ates an important property of eukaryote-type serine/threonine phosphatase (SP-STP) of group A Strepto

258 , how the presence or absence of the cognate serine/threonine phosphatase Stp1 affects Stk1 function

259 , a new mechanism was identified involving a serine/threonine phosphatase, Stp1.

260 tly avoid the taste, is dependent on several serine/threonine phosphatase substrates and the PP1-bind

261 Serine/threonine phosphatases such as PP1 lack substrate

262 ed by inhibition of all known subfamilies of serine/threonine phosphatases, suggesting that multiple

263 lcineurin is a calcium-calmodulin-regulated, serine-threonine phosphatase that functions as a key ind

264 in (PP2B) is a calcium/calmodulin-activated, serine-threonine phosphatase that transmits signals to t

265 PP5 is a serine/threonine phosphatase that also contains four cop

266 Here, we identify PP1 as a serine/threonine phosphatase that associates with and de

267 rotein phosphatase 2A (PP2A) is a multimeric serine/threonine phosphatase that carries out multiple f

268 Calcineurin is a serine/threonine phosphatase that contributes to the eff

269 Experiments were performed to identify the serine/threonine phosphatase that dephosphorylates FOXO1

270 d-type p53-induced phosphatase 1 (WIP1) is a serine/threonine phosphatase that dephosphorylates prote

271 Calcineurin is a calcium-dependent, serine/threonine phosphatase that functions as a signali

272 Calcineurin is a serine/threonine phosphatase that is activated by calciu

273 ex that binds to and inhibits calcineurin, a serine/threonine phosphatase that is activated by TCR en

274 n phosphatase 2A (PP2A) is a multifunctional serine/threonine phosphatase that is critical to many ce

275 We have recently reported that a protein serine/threonine phosphatase that is designated PP5 and

276 The Wip1 gene is a serine/threonine phosphatase that is induced in a p53-de

277 hosphorylation of this site is mediated by a serine/threonine phosphatase that is inhibited by okadai

278 Calcineurin is a serine/threonine phosphatase that is inhibited by the im

279 p53-induced phosphatase PPM1D (or Wip1) is a serine/threonine phosphatase that is transcriptionally u

280 stimulates protein phosphatase 2A (PP2A), a serine/threonine phosphatase that modulates essential si

281 rotein phosphatase 2A (PP2A) is an important serine/threonine phosphatase that plays a role in many b

282 Protein phosphatase 2A (PP2A) is a serine/threonine phosphatase that regulates a diverse ar

283 Protein phosphatase 2A (PP2A) is a major serine/threonine phosphatase that regulates a wide varie

284 neurin (Cn) is a Ca(2+)/calmodulin-dependent serine/threonine phosphatase that regulates differentiat

285 Protein phosphatase 1 (PP1) is a ubiquitous serine/threonine phosphatase that regulates many cellula

286 PGAM5 is a mitochondrial serine/threonine phosphatase that regulates multiple met

287 tresses inhibited activity of calcineurin, a serine/threonine phosphatase that regulates NFAT activat

288 osphatase 2A (PP2A) is a family of mammalian serine/threonine phosphatases that is involved in the co

289 e are conserved between different eukaryotic serine/threonine phosphatases, these results should appl

290 Addition of protein phosphatase 1 gamma, a serine/threonine phosphatase, to rat liver cytosol reduc

291 of bFGF appears to be mediated by a protein serine/threonine phosphatase type 1 or 2A.

292 A complete cDNA of a unique serine/threonine phosphatase type five (TbPP5) was clone

293 reductase active site has been identified in serine-threonine phosphatases using a descriptor built f

294 diated early events, the activity of protein serine/threonine phosphatases was markedly increased in

295 dentified cancer genes was PPP6C, encoding a serine/threonine phosphatase, which harbored mutations t

296 at PDP1 belongs to the PPM family of protein serine/threonine phosphatases, which, in spite of a low

297 uppressor protein phosphatase 2A (PP2A) is a serine/threonine phosphatase whose activity is inhibited

298 Protein phosphatase-2A (PP2A) is an abundant serine/threonine phosphatase with anti-inflammatory acti

299 named PPX or PPP4) is a PP2A-related protein serine/threonine phosphatase with important roles in a v

300 e TGN contains a mutation in PTC1, a type 2c serine/threonine phosphatase with widespread influences.