ライフサイエンスコーパス: serotonin

1 d protects from colitis because of decreased serotonin.

2 ory terminals in the islet were sensitive to serotonin.

3 s in PAECs stimulated with TGF-beta, VEGF or serotonin.

4 This circuitry is extensively modulated by serotonin.

5 Serotonin 1A (5-HT(1A)) autoreceptors regulate brain-wid

6 The serotonin(1A) receptor is a prototypical member of the G

7 namics, ligand binding, and signaling of the serotonin(1A) receptor.

8 state and pinpoint the critical role of the serotonin 2A and 1A receptor systems.

9 acid diethylamide and other agonists of the serotonin 2A receptor (5HT2A-R), induce drastic changes

10 Here we report that serotonin 2c receptor (Htr2c)-expressing neurons in the

11 ed that other serotonergic compounds such as serotonin 4 receptor (5-HT(4)R) agonists could act as pr

12 tives with high affinity and selectivity for serotonin 5-HT(1A) receptors were obtained and tested in

13 ancy induced up-regulation of frontal cortex serotonin 5-HT(2A) receptor (5-HT(2A)R) density in the a

14 In addition to the serotonin 5-HT(2A) receptor (5-HT(2A)R), the dopamine D(

15 Here, we showed that the class A serotonin 5-HT(2A) receptors (5-HT(2A)Rs) affected the l

16 melatonin MT(2) receptors and G(q) -coupled serotonin 5-HT(2C) receptors, in which melatonin transac

17 led neuropeptide Y Y2 receptor (NPY(2)R) and serotonin 5-hydroxytryptamine (HT)(2C) receptor (5-HT(2C

18 n L cells required intact GLP-1 receptor and serotonin 5-hydroxytryptamine receptor 4 (5-HT4) signali

19 m (KCl 60 mM), acetylcholine (ACh 10 muM) or serotonin (5-HT 10 muM).

20 Targeting the serotonin (5-HT) 5-HT(2C) receptor (5-HT(2C)R) allosteri

21 Serotonin (5-HT) and dopamine are critical neuromodulato

22 SNPs near TSPAN5 were associated with plasma serotonin (5-HT) concentrations which were themselves as

23 junctional zone, markedly reduced placental serotonin (5-HT) concentrations, and lowered 5-HT GC imm

24 me-wide significantly associated with plasma serotonin (5-HT) concentrations, which were themselves a

25 is associated with altered dopamine (DA) and serotonin (5-HT) functioning, the current study aimed to

26 Moreover, serotonin (5-HT) has been shown to be a key regulator of

27 cid (AA), dopamine (DA), uric acid (UA), and serotonin (5-HT) in 0.1 M PBS (pH = 7.4).

28 the dorsal raphe nucleus, the main source of serotonin (5-HT) in the mammalian brain, and excessive 5

29 converts the binding of the neurotransmitter serotonin (5-HT) into a transient cation current that me

30 Serotonin (5-HT) is a modulator of neural circuitry unde

31 tryptophan hydroxylase 2 (TPH2), a marker of serotonin (5-HT) neurons.

32 e known to translate environmental cues into serotonin (5-HT) production, contributing to intestinal

33 tracellular recordings, and iontophoresis of serotonin (5-HT) receptor antagonists in the mouse visua

34 Serotonin (5-HT) represents a quintessential neuromodula

35 Serotonin (5-HT) selective reuptake inhibitors (SSRIs) a

36 Herein, the efficient serotonin (5-HT) sensing studies have been conducted usi

37 Excessive serotonin (5-HT) signaling plays a critical role in the

38 itively inhibits nicotinic acetylcholine and serotonin (5-HT) type 3A receptors (5-HT(3A)Rs).

39 Clinical studies indicate that antagonizing serotonin (5-HT) type 3AB (5-HT(3AB)) receptors in brain

40 Activation of serotonin (5-HT) type 4 receptors (5-HT(4)Rs) has been s

41 had significantly increased plasma levels of serotonin (5-HT), and serotonin molecule and SCA plasma

42 tect neurotransmitters, i.e., dopamine (DA), serotonin (5-HT), epinephrine (Epn), and norepinephrine

43 The enteroendocrine signalling compound, serotonin (5-HT), is important for regulating peristalti

44 smitters signaling-such as dopamine (DA) and serotonin (5-HT)-have been independently detected in psy

45 olarization state is modulated by peripheral serotonin (5-hydroxytryptamine [5-HT]).

46 n these neurons, conditional deletion of the serotonin 5A receptor leads to the loss of the physiolog

47 min interneurons express functionally silent serotonin 5A receptors, which translocate to the cell me

48 Serotonin (5HT) is a neuroendocrine hormone synthetized

49 wever, others found that genetic deletion of serotonin (5HT) neurons in the brainstem also prevented

50 histochemical stainings against synapsin and serotonin (5HT), we describe the overall layout as well

51 cells are a subtype of EE cells that produce serotonin (5HT).

52 Serotonin acts through a signal transduction pathway con

53 Surface plasmon resonance shows that serotonin adsorbs with millimolar affinity, and neutron

54 Additionally, repurposing serotonin agonists to inhibit CpxA may represent a poten

55 However, co-injection of serotonin alongside venlafaxine in embryos recovered bra

56 Galpha(s)-coupled GPCRs (e.g., the 5-HT(6) serotonin and D1R dopamine receptor) had reduced ability

57 Serotonin and dopamine are associated with multiple psyc

58 The monoamines serotonin and dopamine are key regulators of sleep in ma

59 Effects of both serotonin and dopamine are mediated largely through thei

60 ng photoperiods, and significantly decreased serotonin and dopamine content throughout the course of

61 ound that AANAT1 limited the accumulation of serotonin and dopamine in the brain upon sleep deprivati

62 eurons and showed that acute itch induced by serotonin and histamine was attenuated in Trpc4-knockout

63 rosophila is well described, the function of serotonin and its downstream receptors on Drosophila olf

64 rvous system PLNs for a community containing serotonin and melatonin receptors.

65 The antidepressant venlafaxine, a selective serotonin and norepinephrine reuptake inhibitor, is pres

66 e serotonin reuptake inhibitors or selective serotonin and norepinephrine reuptake inhibitors (126 RC

67 ricyclic and related antidepressants [TCAs], serotonin and norepinephrine reuptake inhibitors [SNRIs]

68 ls of norepinephrine, epinephrine, dopamine, serotonin and their metabolites, as well as changes in b

69 ntegrin, PTEN and phospholipase C signaling, serotonin and tryptophan metabolism, autophagy, and B ce

70 to neurotransmission, including depletion of serotonin and vitamin B6, in the AIMD mice.

71 d in neurotransmission (GABA, acetylcholine, serotonin, and dopamine) and drug addiction.

72 tored MC granule mediators (e.g., histamine, serotonin, and proteases) and reduced mediator release u

73 ral of the affected regions are modulated by serotonin, and we found that social preference in isolat

74 cell-derived neurotrophic factor (GDNF) nor serotonin are additive with CDNF.

75 Melatonin and serotonin are bioactive compounds present in foods and b

76 ts and provides neuroanatomical evidence for serotonin as a modulator of vocal-acoustic circuitry and

77 opulations of neurons dedicated to detecting serotonin at different concentrations.

78 Indeed, we showed that increasing serotonin bioavailability alters gene expression of sero

79 We hypothesized that increased serotonin bioavailability promotes serotonergic signalin

80 or fluoxetine (reuptake inhibitor) increases serotonin bioavailability.

81 Together with simulation results of apo- and serotonin-bound 5-HT(3A)R, the study reveals a distinct

82 ate their drug actions by rapid elevation of serotonin, but they take several weeks to achieve therap

83 of beta-cells and to pancreas infusion with serotonin, but were not sensitive to insulin.

84 Increasing intestinal serotonin by genetically or pharmacologically inhibiting

85 lt male and female Zfpm1 mutants had reduced serotonin concentration in rostral brain areas and displ

86 ease, or one affecting the number expressing serotonin could alleviate depression.

87 Here, we show that serotonin decreases virulence gene expression by enteroh

88 We have used a simple serotonin-dependent behavior of the roundworm Caenorhabd

89 Serotonin depletion prevented anxiolytic effects induced

90 o-occlusion in SCA; furthermore, circulating serotonin, derived from platelet activation, may play a

91 nt of other sensors and in vitro and in vivo serotonin detection, respectively.

92 ncept, the rGO-PLA electrode was applied for serotonin determination in synthetic urine using differe

93 osphatase alpha) in glia may be modulated by serotonin/dopamine signaling, causing seizure suppressio

94 Action potential firing of serotonin dorsal raphe neurons is driven via alpha1-adre

95 tors, and can synthesize, uptake and degrade serotonin due to the expression of serotonin metabolism-

96 rotransmitter systems were identified (i.e., serotonin, dynorphin, corticotropin-releasing factor, ox

97 t in healthy volunteer participants, we show serotonin enhances the impact of experimentally induced

98 mined for the neurotransmitters dopamine and serotonin, exhibiting linear concentration range from 0.

99 For example, serotonin has a non-monotonic effect on odor responses i

100 has been proposed to promote the activity of serotonin (HTR2C) receptor via its ability to base pair

101 activation of the contralaterally projecting serotonin-immunoreactive deuterocerebral interneurons (C

102 e evidence that venlafaxine exposure reduces serotonin immunoreactivity and tyrosine hydroxylase-posi

103 ation and performing spatial distribution of serotonin immunoreactivity, as well as characterizing ta

104 gside venlafaxine in embryos recovered brain serotonin immunoreactivity, tyrosine hydroxylase-positiv

105 No colocalization was found with serotonin immunostaining.

106 ethod was developed for the determination of serotonin in raw and roasted nuts (almond, Brazil nut, c

107 inery, but little is known about the role of serotonin in the bovine immune system.

108 Periodically modulating the concentration of serotonin in the claustrum, for example, caused a matchi

109 form responsible for sulfonating ~80% of the serotonin in the extracellular brain fluid.

110 genetic evidence that NPVF acts upstream of serotonin in the RN to maintain normal sleep levels.

111 ces sleep in a manner that requires NPVF and serotonin in the RN.

112 In the olfactory circuits of flies and mice, serotonin indirectly inhibits odor responses in olfactor

113 Serotonin induces dephosphorylation of CpxA, which inact

114 We thus establish that serotonin interacts nonspecifically with the membrane at

115 Serotonin is a bioactive factor with immunoregulatory pr

116 Serotonin is a key mediator of stress, anxiety, and depr

117 Thus, MC-derived serotonin is a previously unidentified mechanism of DENV

118 Serotonin is coreleased with insulin and may therefore c

119 ulation of olfactory associative learning by serotonin is mediated by its downstream receptor (d5-HT7

120 The neurotransmitter serotonin is primarily synthesized in the gastrointestin

121 ain development, which may be due to reduced serotonin, leading to altered larval behavior in zebrafi

122 imipramine binding and increased hippocampal serotonin level in rats.

123 The causal relationship between amygdala serotonin levels and an animal's sensitivity to threat w

124 t-like effects, increased norepinephrine and serotonin levels and decreased nuclear factor-kB, tumor

125 hway is developmentally malleable, with high serotonin levels during early life reducing co-transmiss

126 R antagonist and were enhanced by increasing serotonin levels in beta-cells.

127 Controlling unmodified serotonin levels in brain synapses is a primary objectiv

128 nhanced central dopamine and lowered central serotonin levels in increasing activity in the right cau

129 erapeutic effects by elevating extracellular serotonin levels in the brain, and remodel the structura

130 his polymorphism and early-life stress alter serotonin levels, our findings support a potential molec

131 ed fish could be rescued by acutely reducing serotonin levels.

132 mostly independent of aberrant extracellular serotonin levels.

133 Human and rodent immune cells express the serotonin machinery, but little is known about the role

134 educed levels of norepinephrine, dopamine or serotonin, mainly in the brainstem.

135 tion through a paracrine GLP-1-dependent and serotonin-mediated mechanism.

136 d degrade serotonin due to the expression of serotonin metabolism-related genes.

137 known about the exact mode of action of the serotonin metabolite and the possible interplay between

138 ipsoid body neurons that form the heart of a serotonin-modulated circuit that controls sleep architec

139 eased plasma levels of serotonin (5-HT), and serotonin molecule and SCA plasma induced neutrophil CXC

140 animal research indicates that dopamine and serotonin, neuromodulators traditionally linked to appet

141 (5-HT(1A)) autoreceptors regulate brain-wide serotonin neuron firing and are positioned to assert lar

142 Blocking serotonin neuron glutamate co-transmission mimics this S

143 ere, we show in the mouse that raphe nucleus serotonin neurons activate ventral tegmental area dopami

144 ession, and novel therapeutic targets within serotonin neurons are needed to combat these disorders.

145 The last to show Fgf8 lineage are those serotonin neurons in the lateral wings and those at the

146 ly excluded from Fgf8- lineage at T-E9.5 are serotonin neurons in the MnR and caudal-intrafascicular

147 e correlates with organizational features of serotonin neurons in these nuclei.

148 Our data demonstrate that serotonin neurons modulate dopamine neuron activity via

149 w stress alters the translational profile of serotonin neurons, we sequenced ribosome-associated RNA

150 of in vivo citalopram administration on the serotonin neurotransmitter system was studied in the hip

151 individuals with depression and treated with serotonin-norepinephrine reuptake inhibitor (N = 424) we

152 ective serotonin reuptake inhibitors [SSRI], serotonin-norepinephrine reuptake inhibitors [SNRI], tri

153 ribute to the antidepressant efficacy of the serotonin/norepinephrine reuptake inhibitor venlafaxine

154 or rat 5-HT(2A) receptor by agonists such as serotonin or 2,5-dimethoxy-4-iodoamphetamine (DOI) led t

155 h will determine whether manipulation of the serotonin pathway could be a feasible approach to bolste

156 In the serotonin pathway, the metabolite N-acetylserotonin (NAS

157 y metabolites produced by the kynurenine and serotonin pathways.

158 an studies, the manipulation of dopamine and serotonin play an important role in the processing of mo

159 Serotonin plays a central role in cognition and is the t

160 sitive (PV), somatostatin positive (SOM) and serotonin positive neurons.

161 ting milk replacer with 5-hydroxytryptophan (serotonin precursor) or fluoxetine (reuptake inhibitor)

162 Serotonin production by enterochromaffin cells (ECs) is

163 eriment targeted candidate genes involved in serotonin production, metabolism, transport, signaling a

164 ssRNA) from intestinal microbiota to promote serotonin production.

165 diarrhoea may be related to variation in the serotonin re-uptake transporter (SERT) gene.

166 Serotonin reaches the AL via the diffusion of paracrine

167 on of the serotonin transporter (SLC6A4) and serotonin receptor (HTR1A, HTR2A, HTR2C) genes with anxi

168 erstood, although activation of the 5-HT(2A) serotonin receptor (HTR2A) is key.

169 Administration of the serotonin receptor 1A partial agonist buspirone prevente

170 on occurred primarily through stimulation of serotonin receptor 5-HT(1A).

171 P, calcitonin-gene related peptide, and the serotonin receptor 5-HT(3)R.

172 imal studies have shown that knockout of the serotonin receptor 7 gene (HTR7) resulted in an antidepr

173 5-HT(2A) (Q pathway) and 5-HT(7) (S pathway) serotonin receptor activation cancels phrenic motor faci

174 g development and injury, and is promoted by serotonin receptor agonists.

175 homomeric 5-hydroxytryptamine 3A (5-HT(3A)) serotonin receptor for 15 to 20 mus to demonstrate that

176 st strongly in the amygdala, but none of the serotonin receptor genes, were predictive of interindivi

177 istidine sensor kinase, CpxA, is a bacterial serotonin receptor.

178 polarization of neutrophils, suggesting that serotonin-receptor antagonists or serotonin reuptake inh

179 sma induced neutrophil CXCR4 expression in a serotonin-receptor-dependent manner.

180 Serotonin receptors (5-HT(3A)R) play a crucial role in r

181 in and its receptor, estrogen receptor beta, serotonin receptors (Htr1a, Htr2a) and glutamate recepto

182 in bioavailability alters gene expression of serotonin receptors and immune-related genes.

183 istent both with the known actions of LSD on serotonin receptors and with limited evidence that highe

184 While the expression of the serotonin receptors did not show a significant relations

185 ying behavior required the G protein-coupled serotonin receptors SER-1 and SER-7, and the G(q) orthol

186 Here we show that preassociation of 5-HT(7) serotonin receptors with G(s) heterotrimers is necessary

187 vine peripheral leukocytes express all known serotonin receptors, and can synthesize, uptake and degr

188 screen yielded agonists of G protein-coupled serotonin receptors, protein kinase C agonists, and a mi

189 tory macrophages differ in the expression of serotonin receptors, with 5-HT(2B) and 5-HT(7) expressio

190 affective disorders, we investigated whether serotonin-related gene expression across the brain's emo

191 rus replication, inhibited rotavirus-induced serotonin release and fluid secretion, and reduced diarr

192 as been hampered by our inability to monitor serotonin release and transport with high spatial and te

193 ent assay optical density thresholds and the serotonin release assay in patients on extracorporeal me

194 Patients were divided into two cohorts, serotonin release assay negative and serotonin release a

195 ohorts, serotonin release assay negative and serotonin release assay positive.

196 ombocytopenia without sending a confirmatory serotonin release assay.

197 Without serotonin release by maternal neurons, FACT is not recru

198 nstrate that iSeroSnFR can be used to detect serotonin release in freely behaving mice during fear co

199 )C]CIMBI-36 binding is sensitive to synaptic serotonin release in the human brain, and when combined

200 , such as suppression of acute stress-evoked serotonin release, stimulation of adult neurogenesis and

201 rs, estimation of 5-hydroxytryptamine (5-HT; Serotonin) release has proved to be challenging.

202 We show that in Caenorhabditis elegans, serotonin released by maternal neurons during stress ens

203 st buspirone prevented the isolation-induced serotonin response to novelty in the level of the whole

204 onged social isolation disrupts the specific serotonin response which gets restored by chronic antide

205 a10 corticostriatal neurons exhibit distinct serotonin responses and have increased excitability, com

206 atures in S100a10 neurons that contribute to serotonin responses and strongly associate with psychomo

207 Exogenous serotonin restored their sensitivity to gliotoxin, indic

208 ed responses were reduced by the blockade of serotonin reuptake in the amygdala.

209 er a single 20-mg oral dose of the selective serotonin reuptake inhibitor (SSRI) citalopram or placeb

210 itive-behavioral therapy (CBT) and selective serotonin reuptake inhibitor (SSRI) treatment outcome in

211 via direct amygdala infusions of a selective serotonin reuptake inhibitor (SSRI), citalopram.

212 Chronic administration of a selective serotonin reuptake inhibitor (SSRI), fluoxetine, increas

213 c, but not acute, treatment with a selective serotonin reuptake inhibitor (SSRI).

214 benefit are often switched to non-selective serotonin reuptake inhibitor agents.

215 o benefit from bupropion following selective serotonin reuptake inhibitor failures.

216 mented behavioral responses to the selective serotonin reuptake inhibitor fluoxetine but not desipram

217 treatments-cognitive behavioral therapy and serotonin reuptake inhibitor medication-for managing bot

218 2 by the clinically approved antidepressant, serotonin reuptake inhibitor paroxetine (PX), recapitula

219 ch were themselves associated with selective serotonin reuptake inhibitor treatment outcomes in patie

220 of depression, length of lifetime selective serotonin reuptake inhibitor use, or lifetime length of

221 vo-administered drug citalopram, a selective serotonin reuptake inhibitor, in mouse brain tissue sect

222 Selective serotonin reuptake inhibitors (SSRIs) are standard of ca

223 Selective serotonin reuptake inhibitors (SSRIs) are the most widel

224 f amygdala serotonin reuptake with selective serotonin reuptake inhibitors (SSRIs) confirmed the caus

225 Selective serotonin reuptake inhibitors (SSRIs) constitute a first

226 w-strength evidence was found that selective serotonin reuptake inhibitors (SSRIs) do not reduce cann

227 sporter or postnatal blockade with selective serotonin reuptake inhibitors (SSRIs) leads to novelty-i

228 Most antidepressants, including selective serotonin reuptake inhibitors (SSRIs), initiate their dr

229 HTR7 and clinical response to four selective serotonin reuptake inhibitors (SSRIs: citalopram, paroxe

230 e, antidepressant use and classes (selective serotonin reuptake inhibitors [SSRI], serotonin-norepine

231 all, for 4 antidepressant classes (selective serotonin reuptake inhibitors [SSRIs], tricyclic and rel

232 Standard guidelines recommend selective serotonin reuptake inhibitors as first-line antidepressa

233 sting that serotonin-receptor antagonists or serotonin reuptake inhibitors could represent therapeuti

234 re nondopaminergic approaches (eg, selective serotonin reuptake inhibitors for psychiatric symptoms,

235 in 5 systematic reviews) and with selective serotonin reuptake inhibitors or selective serotonin and

236 Findings for prenatal exposure to selective serotonin reuptake inhibitors were similar.

237 nt to the first line of treatment (selective serotonin reuptake inhibitors)(1).

238 d that n-3 PUFAs and escitalopram (selective serotonin reuptake inhibitors, SSRIs) treatment increase

239 cluding tricyclic antidepressants, selective serotonin reuptake inhibitors, tegaserod, and histamine-

240 etics, antiparkinsonian drugs, and selective serotonin reuptake inhibitors, we sought to determine th

241 Targeting of amygdala serotonin reuptake with selective serotonin reuptake inh

242 e serotonin transporter (SERT) by inhibiting serotonin reuptake.

243 at the selective 5-hydroxytryptamine (5-HT) (serotonin) reuptake inhibitor (SSRI) fluoxetine (Flx) is

244 vel candidate mechanism for the unfolding of serotonin's antidepressant effects over time.

245 ate a high-performance, soluble, fluorescent serotonin sensor (iSeroSnFR), enabling optical detection

246 Administration of 3-indolepropionic acid, serotonin, short chain fatty acids or tauroursodeoxychol

247 otonergic agonists potentiates an endogenous serotonin signal to affect behavior.

248 ate with vagal sensory neurons, likely using serotonin signaling as a transduction mechanism.

249 The serotonin transporter (SERT) terminates serotonin signaling by rapid presynaptic reuptake.

250 monitoring sub-second striatal dopamine and serotonin signaling during a visual motion discriminatio

251 in reveal a role for sub-second dopamine and serotonin signaling in non-reward-based aspects of cogni

252 bolite not previously known to interact with serotonin signaling pathways: the disulfide-bridged 2,5-

253 Importantly, serotonin signaling through 5-HT4 mimicked the effects o

254 ased screen for natural products that affect serotonin signaling.

255 epressant medication that acts by amplifying serotonin signaling.

256 Both insulin and serotonin stimulated opioid signaling, whereas NHR-69 su

257 Conversely, inhibiting serotonin synthesis increases pathogenesis and decreases

258 e rate limiting enzyme regulating peripheral serotonin synthesis.

259 challenge, the evaluation of the human brain serotonin system in neuropsychiatric disorders, such as

260 e contribute to our understanding of how the serotonin system underlies an individual's expression of

261 The dopamine and serotonin systems are impacted by photoperiod and are co

262 is elegans neuropeptide Y/neuropeptide F and serotonin that could aid in our understanding of the mol

263 ystems that signal reward, like dopamine and serotonin, that damage not only affects our mood and pat

264 hat this compound synergizes with endogenous serotonin to elicit behavior.

265 ould exploit the interactions between OT and serotonin to regulate social functions.

266 is a shift in the tryptophan metabolism from serotonin to the kynurenine pathway, across these psychi

267 binding of 5-hydroxytryptamine (5-HT) (i.e., serotonin) to the binding pocket located on the extracel

268 , and, in one participant, both dopamine and serotonin tracked deviations from expected trial transit

269 multi-scale encoding: in three participants, serotonin tracked sensory uncertainty, and, in one parti

270 on unique to primates-with both dopamine and serotonin tracking decision times.

271 bling optical detection of millisecond-scale serotonin transients.

272 e the outward-open conformation, and inhibit serotonin transport.

273 Antidepressants target the serotonin transporter (SERT) by inhibiting serotonin reu

274 In addition, serotonin transporter (SERT) expression was upregulated

275 to assess D(2)/D(3), 5-HT(1A), 5-HT(2A) and serotonin transporter (SERT) occupancies of brexpiprazol

276 The serotonin transporter (SERT) terminates serotonin signal

277 ciation of region-specific expression of the serotonin transporter (SLC6A4) and serotonin receptor (H

278 med the causal relationship between amygdala serotonin transporter and an animal's sensitivity to thr

279 or binding affinities at DAT, as well as the serotonin transporter and sigma(1) receptors.

280 capacitance induced by ligand binding to the serotonin transporter and to the glycine transporters (G

281 findings provide evidence that high amygdala serotonin transporter expression contributes to the high

282 havior in any of the targeted brain regions, serotonin transporter expression, specifically within th

283 We also developed a robust assay of serotonin transporter function and modulation by drugs.

284 plicated in emotion regulation revealed that serotonin transporter gene expression in the ventrolater

285 Knockout of the serotonin transporter or postnatal blockade with selecti

286 to the lumen and subsequently removed by the serotonin transporter, SERT.

287 urons expressing the biosynthetic enzyme for serotonin, tryptophan-hydroxylase-2 (TPH2), in the ventr

288 Serotonin turnover (ratio 5-HIAA/5-HT) was reduced in ex

289 l as characterizing target genes involved in serotonin turnover in the zebrafish brain.

290 The serotonin type 3 receptor (5-HT(3)) is a ligand-gated io

291 The serotonin type 3A (5-HT(3A)) receptor is a homopentameri

292 The intracellular domain of the serotonin type 3A receptor, a pentameric ligand-gated io

293 Lowered serotonin was not due to either reduced synthesis or inc

294 ith the limbic system, and it was shown that serotonin was significantly increased (2-fold), but its

295 lated circuitry is modulated by dopamine and serotonin, we examined, for the first time, whether rewa

296 hormones including cortisol, adrenaline, and serotonin were abnormally observed in the serum levels o

297 : 1 and inverse associations with valine and serotonin were also observed, although these association

298 c neurons and mutants that cannot synthesize serotonin were profoundly resistant to gliotoxin.

299 oxyindoleacetic acid, the main metabolite of serotonin, were increased.

300 nucleus is the predominant source of central serotonin, where neuronal activity regulates complex emo