ライフサイエンスコーパス: serrated

1 ghout the colon, of which more than 50% were serrated.

2 ould also harbor BRAF mutations and that non-serrated ACF would not.

3 tations would be found more often in the non-serrated ACF.

4 detailed process of progression from sessile serrated adenoma (SSA) to dysplasia and carcinoma has no

5 aditional serrated adenoma (TSA), or sessile serrated adenoma (SSA) with villous characteristics (>/=

6 as cancer or a tubular adenoma, traditional serrated adenoma (TSA), or sessile serrated adenoma (SSA

7 rsor lesion, the proximal hyperplastic polyp-serrated adenoma pathway.

8 as without dysplasia, as well as traditional serrated adenoma with dysplasia.

9 ma with low grade dysplasia, n = 27; sessile serrated adenoma, n = 4; tubulovillous adenoma with high

10 AF mutation were pathologically proven to be serrated adenoma.

11 CRC precursor lesions (including sessile serrated adenoma/polyps (SSA/P), traditional serrated ad

12 d sites was significantly higher in sporadic serrated adenomas (2.0 +/- 1.7) than in tubular adenomas

13 IMP-high) was also more frequent in sporadic serrated adenomas (68%, 15 of 22) than in tubular adenom

14 al adenomatous polyposis (n = 18) or sessile serrated adenomas (n = 15) and normal colonic tissue fro

15 perplastic polyps (n = 34; 32%), traditional serrated adenomas (n = 3; 3%), sessile serrated adenomas

16 redominance of HPs in the right colon and/or serrated adenomas (P = 0.0009) and were associated with

17 Sessile serrated adenomas (SSAs) and traditional serrated adenom

18 hat contribute to the development of sessile serrated adenomas (SSAs).

19 ted adenomas/polyps (SSA/Ps) and traditional serrated adenomas (TSAs) are now distinguished from hype

20 ile serrated adenomas (SSAs) and traditional serrated adenomas (TSAs) constituted 36.8% (137 of 372)

21 We therefore evaluated CIMP in 22 sporadic serrated adenomas and 6 serrated adenomas with multiple

22 CpG island methylation is common in sporadic serrated adenomas and may play an important role in thei

23 Human sessile serrated adenomas and right-sided colorectal tumors with

24 nly hyperplastic polyps but also traditional serrated adenomas and sessile serrated adenomas.

25 Traditional serrated adenomas and SSLs are precursors to colorectal

26 Serrated adenomas are characterized by a saw-toothed gro

27 In this study, SSA/Ps and traditional serrated adenomas are referred to collectively as STSAs.

28 subgroup analysis was performed for sessile serrated adenomas for 2007-2012.

29 The polyps in our patients and control serrated adenomas had a decrease or absence of endocrine

30 Patients with sporadic serrated adenomas had a higher frequency of hyperplastic

31 Sporadic serrated adenomas had significantly more frequent methyl

32 p studies, premalignant potential of sessile serrated adenomas has been described and screening utili

33 pigenetic alterations in the pathogenesis of serrated adenomas is not clear.

34 oreover, ectopic crypts found in traditional serrated adenomas show basal LGR5 mRNA, indicating that

35 ps in our patients were much more similar to serrated adenomas than to hyperplastic polyps and were c

36 antly greater binding to tubular and sessile serrated adenomas versus hyperplastic polyps and normal

37 Sessile serrated adenomas were uncommon (n = 417, 4.5 %), with g

38 All five serrated adenomas with admixed hyperplastic glands and a

39 CIMP in 22 sporadic serrated adenomas and 6 serrated adenomas with multiple (6 to 10) hyperplastic p

40 ons includes hyperplastic polyps and sessile serrated adenomas without dysplasia, as well as traditio

41 ific polymerase chain reaction in 102 HPs, 8 serrated adenomas, 19 tubular adenomas, and 9 adenocarci

42 resected colorectal cancer, and in 70 HPs, 4 serrated adenomas, 3 admixed hyperplastic-adenomatous po

43 f HPs (P = 0.01 versus sporadic HPs), 75% of serrated adenomas, 33% of admixed hyperplastic-adenomato

44 and molecular characteristics of 129 HPs, 6 serrated adenomas, and 3 admixed hyperplastic-adenomatou

45 tegories of hyperplastic polyps, traditional serrated adenomas, and sessile serrated lesions (SSLs).

46 of human hyperplastic polyps (HPPs), sessile serrated adenomas, and traditional serrated adenomas.

47 ing also is activated in human HPPs, sessile serrated adenomas, and traditional serrated adenomas.

48 ed polyps, particularly SSLs and traditional serrated adenomas, have an increased risk of synchronous

49 pression of GREM1 also occurs in traditional serrated adenomas, sporadic premalignant lesions with a

50 serrated adenoma/polyps (SSA/P), traditional serrated adenomas, tubular adenomas >/=10 mm or with hig

51 ed adenomas/polyps (SSA/Ps), and traditional serrated adenomas.

52 , sessile serrated adenomas, and traditional serrated adenomas.

53 , sessile serrated adenomas, and traditional serrated adenomas.

54 so traditional serrated adenomas and sessile serrated adenomas.

55 hyperplastic polyps, adenomas, and solitary serrated adenomas.

56 indicate that the polyps in our patients are serrated adenomas.

57 ional serrated adenomas (n = 3; 3%), sessile serrated adenomas/polyps (SSA/Ps) (n = 70; 66%), unspeci

58 Sessile serrated adenomas/polyps (SSA/Ps) and traditional serrat

59 SPs comprise hyperplastic polyps, sessile serrated adenomas/polyps (SSA/Ps), and traditional serra

60 ints included conventional adenomas, sessile serrated adenomas/polyps (SSA/Ps), or colorectal cancer,

61 gh protein expression, especially in sessile serrated adenomas/polyps and Lynch syndrome.

62 6.8%; relative risk = 2.1), and for sessile serrated adenomas/polyps than for conventional adenomas

63 body fat, tended to be stronger for sessile serrated adenomas/polyps than hyperplastic polyps.

64 human colorectal tissue samples--48 sessile serrated adenomas/polyps, 70 sporadic high-grade dysplas

65 Serrated adenomatous polyposis has not been described be

66 It is found that the dark side is serrated and comprised of coherent twin boundaries and s

67 rences in the stem cell dynamics between the serrated and conventional pathways of colorectal carcino

68 Although Kras/KRAS mutation promotes serrated and hyperplastic morphologic features in colon

69 plastic lesions were further classified into serrated and non-serrated histologies, there was a stron

70 tional types of dysplasia, such as foveolar, serrated, and early crypt dysplasia, which make interpre

71 gative, and KRAS mutation positive; n = 58), serrated (any MSI, CIMP high, BRAF mutation positive, an

72 ated kinases (ERK)1/2 were phosphorylated in serrated areas of human hyperplastic polyps (HPPs), sess

73 colony types: smooth (S), wrinkled (W), and serrated (C).

74 >80% liver metastases) in Kras(G12D)-driven serrated cancer.

75 They possessed large, saber-form serrated canine teeth, powerful forelimbs, a sloping bac

76 Here, we review recent evidence on how serrated carcinogenesis contributes to the subtype of CR

77 inology and reporting, but the prevalence of serrated class polyps is 20%-40% in average-risk individ

78 iciency thereby generates fertile ground for serrated colorectal cancer formation in the intestine, p

79 The morphologic features of serrated colorectal lesions, the molecular alterations t

80 F(V600E) mutation was identified in 10 of 16 serrated compared with 1 of 33 non-serrated lesions (P =

81 sely, KRAS mutations were present in 3 of 16 serrated compared with 14 of 33 non-serrated lesions.

82 n act as a potential tumor suppressor in the serrated CRC pathway by inhibiting Wnt/beta-catenin sign

83 colorectal cancer (CRC) associated with the serrated CRC pathway.

84 Activation of Kras led to hyperplasia and serrated crypt architecture akin to that observed in hum

85 xtant predatory lizards and their ziphodont (serrated, curved and blade-shaped) teeth make them valua

86 ethyl methanesulfonate (EMS) mutant, deeply serrated (des), in the woodland strawberry Fragaria vesc

87 hosphorylation of EGFR and ERK1/2 within the serrated epithelium.

88 usion of lesions that were obviously SMIC or serrated, factors associated with covert SMIC were recto

89 owls fly with astonishing stealth due to the serrated feather morphology that produces advantageous f

90 ncluding aberrant cotyledon vein patterning, serrated floral organs, and reduced stature, but plants

91 The statistical and dynamic analyses of the serrated-flow behavior in the nanoindentation of a high-

92 The analyses of serrated flows reveal plentiful and useful information o

93 e contact line adopts a peculiar micrometric serrated form.

94 cinogenesis (ie, traditional, alternate, and serrated) have been proposed, based on specific combinat

95 ere further classified into serrated and non-serrated histologies, there was a strong inverse relatio

96 trong association between BRAF mutations and serrated histology in hyperplastic ACF supports the idea

97 enomas, and hyperplastic polyps exhibiting a serrated histology were very likely to possess BRAF muta

98 gy was defined as an adenoma with villous or serrated histology, high-grade dysplasia, or an invasive

99 same advanced colonic lesions exhibited non-serrated histology, they were wild type for BRAF; among

100 est IRR after adjusting for size and sessile serrated histology.

101 unofluorescence microscopy showed a linear n-serrated IgG deposition pattern along the basement membr

102 The serrated leaf morphology of abh1 is similar to the serra

103 ERING LOCUS C (FLC) and which also result in serrated leaf morphology were identified in T-DNA and fa

104 independent roles in the formation of simple serrated leaves and in the suppression of bract formatio

105 opment, reduced plant growth, and virescent, serrated leaves but were viable and produced seed.

106 ruct in which the uORF was mutated exhibited serrated leaves, compact rosettes, and, most significant

107 10), exhibited developmental defects such as serrated leaves, curled stems, contorted flowers and twi

108 h abnormally shaped lateral organs including serrated leaves, narrow floral organs, and petals that c

109 and in addition showed a reduced stature and serrated leaves.

110 with decreased internode length and smaller serrated leaves.

111 nadvanced adenomas, or an adenoma or sessile serrated lesion >=10 mm.

112 udies have evaluated meat intake and sessile serrated lesion (SSL) risk, a recently recognized precur

113 Endoscopist ADR and sessile serrated lesion detection rate (SSLDR) were determined b

114 No differences were observed in the serrated lesion detection rate of NBI versus HD-WLE: 47.

115 patients with previous serrated lesions, the serrated lesion detection rate was similar with NBI and

116 revalence of the immediate precursor sessile serrated lesion with dysplasia were demonstrated.

117 ures or high-grade dysplasia, any dysplastic serrated lesion, or invasive cancer.

118 ting serrated lesions in patients with prior serrated lesions > 5 mm not completely fulfilling serrat

119 Results Nondiminutive serrated lesions (>/=6 mm) were seen at CT colonography-

120 cation (11.7% vs 10.2%; P = .68), or sessile serrated lesions (3.9% vs 5.5%; P = .55), respectively.

121 10 of 16 serrated compared with 1 of 33 non-serrated lesions (P = 0.001); conversely, KRAS mutations

122 , traditional serrated adenomas, and sessile serrated lesions (SSLs).

123 evaluated for the presence of nondiminutive serrated lesions and advanced adenomas.

124 Conclusion Serrated lesions are seen at CT colonography-based scree

125 serrated lesions removed, and total sessile serrated lesions count as predictors of dysplastic sessi

126 In contrast, serrated lesions display basal localization of LGR5, and

127 We excluded serrated lesions from the analysis of covert SMIC due to

128 In contrast, 55% of serrated lesions harbored mutant BRAF, 26% were CIMP-hig

129 ggest that SSPs and other large, right-sided serrated lesions have a unique molecular profile that is

130 However, pancolonic chromoendoscopy detected serrated lesions in a significantly higher proportion of

131 white-light endoscopy (HD-WLE) in detecting serrated lesions in patients with prior serrated lesions

132 or accuracy in predicting dysplastic sessile serrated lesions in serrated polyposis syndrome patients

133 Risk factors for CIMP-high-serrated lesions included Caucasian race, current smokin

134 The family of serrated lesions includes hyperplastic polyps and sessil

135 ons included one or more adenomas or sessile serrated lesions measuring at least 1 cm in the longest

136 ups in proportions of patients found to have serrated lesions of 5 mm or larger (9.4% vs 7.0%; P = .4

137 dysplasia and villous histology), number of serrated lesions per colonoscopy, and adenoma miss rate

138 lorectal cancer, size of the largest sessile serrated lesions removed, and total sessile serrated les

139 There were 580 conventional adenomas and 419 serrated lesions successfully assayed.

140 The presence of high-grade dysplasia in serrated lesions was uncommon when compared with advance

141 Large right-sided serrated lesions were confirmed in 20 individuals (1.4%)

142 tics that may contribute to visualization of serrated lesions were investigated, including polyp size

143 Detection rates for proximal serrated lesions were significantly higher in the chromo

144 status, and a history of polyps, whereas for serrated lesions with mutant BRAF, the significant risk

145 mately resected were neoplastic (adenomas or serrated lesions), of which 43% (nine of 21) were charac

146 d 36.8% (137 of 372) and 4.3% (16 of 372) of serrated lesions, respectively; hyperplastic polyps (HPs

147 In patients with previous serrated lesions, the serrated lesion detection rate was

148 3 of 16 serrated compared with 14 of 33 non-serrated lesions.

149 95% CI, 1.10-1.56, P(trend) = .02), but not serrated lesions.

150 s were created to predict dysplastic sessile serrated lesions.

151 ns count as predictors of dysplastic sessile serrated lesions.

152 up CT colonography, many of which were flat, serrated lesions.

153 Fx-/- mice developed colitis and serrated-like lesions.

154 oss of JAGGED function causes organs to have serrated margins.

155 ignificantly increased detection of proximal serrated neoplasia and other polyp types compared with s

156 rectal cancer by means of a new pathway: the serrated neoplasia pathway.

157 Progression to serrated neoplasia requires cells to escape OIS via inac

158 f chromocolonoscopy on detection of proximal serrated neoplasia.

159 contained the terms risk or risk factor, and serrated or hyperplastic, and polyps or adenomas, and co

160 or simple) and leaf margin pattern (entire, serrated, or lobed).

161 atellite instability, and alterations in the serrated pathway and DNA methylation.

162 itiation and progression of dysplasia in the serrated pathway are documented.

163 of SP development and indicate that risk of serrated pathway colorectal neoplasms could be reduced w

164 Also, in women, the risk of CRC with the serrated pathway features was more strongly increased wi

165 The serrated pathway is characterized by mutations in RAS an

166 gnificant proportion of which arise from the serrated pathway of carcinogenesis.

167 6Ink4a inactivation, and p53 mutation in the serrated pathway of colon cancer development.

168 colorectal cancers are developed through the serrated pathway of tumorigenesis, which is associated w

169 veillance was evaluated with the Adenoma and Serrated Pathway to Colorectal Cancer (ASCCA) model.

170 Microsimulation using the ASCCA (Adenoma and Serrated pathway to Colorectal CAncer) model.

171 (V600E) mutation is a driver mutation in the serrated pathway to colorectal cancers.

172 nel, or a potentially initiating step on the serrated pathway to colorectal carcinoma.

173 0% of colorectal cancers develop through the serrated pathway.

174 colorectal carcinogenesis can occur via the serrated pathway.

175 Less is known about the alternative 'serrated' pathway, which has been associated with BRAF m

176 sociated with the traditional, alternate, or serrated pathways, but was associated with a subset of p

177 ow the effectiveness of CNN approaches for u-serrated pattern recognition with a high accuracy.

178 Due to unfamiliarity with serrated patterns, serration pattern recognition is stil

179 has wrinkled leaves with deeper serrations, serrated petals and deformed carpels.

180 rous lesion found in the colon, exhibiting a serrated phenotype would also harbor BRAF mutations and

181 atients with prior detection of at least one serrated polyp >=10 mm or >= 3 serrated polyps larger th

182 (n = 1,439) and 0.85 (95% CI, 0.75-0.97) for serrated polyp (n = 1,878).

183 Serrated polyp (SPs) are precursors to 20% to 30% of cas

184 nd 2007 and comprised 628 adenoma cases, 594 serrated polyp cases, 247 cases with both types of polyp

185 h elevated adenoma detection (32.3%) but not serrated polyp detection (3.2%).

186 contrast material tagging markedly improved serrated polyp detection with an odds ratio of 40.4 (95%

187 ed by PDGFRA(+) fibroblasts is important for serrated polyp development.

188 dicate roles for immune and stromal cells in serrated polyp development.

189 rom myeloid cells during the early stages of serrated polyp development.

190 findings (adenoma, advanced adenoma, sessile serrated polyp) were analyzed in association with cancer

191 nfirm the functions of previously identified serrated polyp-associated molecules and indicate roles f

192 ing at least 1 hamartomatous or hyperplastic/serrated polyp.

193 The SIR for CRC in patients with serrated polyposis (0.51; 95% CI, 0.01-2.82) did not dif

194 ta from 53 patients who met the criteria for serrated polyposis and 145 patients who did not meet the

195 was similar between patients with confirmed serrated polyposis and multiple serrated polyps (odds ra

196 Patients with serrated polyposis syndrome (SPS) are advised to undergo

197 ted lesions > 5 mm not completely fulfilling serrated polyposis syndrome (SPS) criteria.

198 asis, and risk of dysplasia and neoplasia of serrated polyposis syndrome are incompletely understood.

199 Logistic regression identified; older age at serrated polyposis syndrome diagnosis, a personal histor

200 cting dysplastic sessile serrated lesions in serrated polyposis syndrome patients.

201 g the World Health Organization criteria for serrated polyposis syndrome, and their relatives have si

202 ated polyps who do not meet the criteria for serrated polyposis, and in their first-degree relatives,

203 cts with multiple SSAs; most had features of serrated polyposis.

204 orectal cancer (CRC) as those diagnosed with serrated polyposis.

205 s similar to that of patients diagnosed with serrated polyposis.

206 ween first-degree relatives of these groups (serrated polyposis: 3.28, 95% CI, 2.16-4.77; multiple se

207 , and 15.6% had conventional adenomas and/or serrated polyps >/=6 mm.

208 a trend towards increased identification of serrated polyps (0.15 vs 0.07) and all neoplastic (adeno

209 om the SIR for CRC in patients with multiple serrated polyps (0.74; 95% CI, 0.20-1.90; P = .70).

210 vs 8.2%; P = .73) or clinically significant serrated polyps (10.0% vs 10.3%; P = .82) at the follow-

211 lternative definition of clinically relevant serrated polyps (12.3%; 95% CI, 9.3-15.4; P < .001).

212 oxin to HBUS mice accelerated development of serrated polyps (95% of treated mice developed polyps be

213 whether detection of proximal nondysplastic serrated polyps (ND-SP) at screening and surveillance co

214 th confirmed serrated polyposis and multiple serrated polyps (odds ratio, 1.35; 95% confidence interv

215 ing that it is also associated with multiple serrated polyps (odds ratio, 460; 95% confidence interva

216 h sessile serrated polyps but not with other serrated polyps (P = 0.02).

217 right-sided conventional adenomas (cAD) and serrated polyps (SP) compared to cecal intubation in a l

218 GROUND & AIMS: Certain subsets of colorectal serrated polyps (SP) have malignant potential.

219 Certain subsets of colorectal serrated polyps (SP) have malignant potential.

220 CKGROUND & AIMS: Surveillance guidelines for serrated polyps (SPs) are based on limited data on longi

221 tial localization of some neoplasms, such as serrated polyps (SPs), in specific areas of the intestin

222 Little is known about the natural history of serrated polyps (SPs), partly due to the lack of large-s

223 highest prevalence of markers was in sessile-serrated polyps (SSP) of >/=10 mm that were in the right

224 Sessile serrated polyps (SSPs) could account for a substantial p

225 wever, serrated polyps, particularly sessile serrated polyps (SSPs), are increasingly acknowledged as

226 atures of AA patients diagnosed with sessile serrated polyps (SSPs).

227 CRC, advanced adenomas, or large (>/=10 mm) serrated polyps after 3 surveillance colonoscopies were

228 6.7 % with high-grade dysplasia (HGD), 9.6 % serrated polyps and 11.2 % adenocarcinomas.

229 y interval increases the detection of missed serrated polyps and could change the diagnosis of SPS in

230 owered for improved detection of significant serrated polyps and for longer-term follow-up to investi

231 Human intestinal serrated polyps are a heterogeneous group of benign lesi

232 py interval colorectal cancers are proximal; serrated polyps are often precursors to these cancers an

233 gher proportion of subjects with significant serrated polyps as well as a higher total number of sign

234 enoma, 1.47; 95% CI, 1.27-1.71), more than 3 serrated polyps at the index examination (RR=2.16, 95% C

235 ry of colorectal cancer and detection of 1-2 serrated polyps at the index examination.

236 Detection rates of significant serrated polyps between both arms were compared using th

237 ation was positively correlated with sessile serrated polyps but not with other serrated polyps (P =

238 of EGFR protein and phosphorylation in human serrated polyps by immunohistochemical and immunoblot an

239 well as a higher total number of significant serrated polyps compared to standard colonoscopy (12.8%

240 Development of serrated polyps depends on the composition of the gut mi

241 om WNT-driven expansion of stem cells, while serrated polyps derive from differentiated cells through

242 is 20%-40% in average-risk individuals; most serrated polyps detected are hyperplastic.

243 ystem can increase detection of adenomas and serrated polyps during colonoscopy in comparison to hist

244 Epidemiology studies of serrated polyps have been hampered by inconsistencies in

245 report the prevalence and characteristics of serrated polyps identified in a large, average-risk popu

246 US28) in intestinal epithelial cells develop serrated polyps in the cecum.

247 These serrated polyps include not only hyperplastic polyps but

248 ariations in rate of endoscopic detection of serrated polyps indicate the need for careful examinatio

249 at least one serrated polyp >=10 mm or >= 3 serrated polyps larger than 5 mm, both proximal to the s

250 cerous lesions (advanced adenomas or sessile serrated polyps measuring >/=1 cm in the greatest dimens

251 For nonadvanced adenomas and for serrated polyps overall, only rs961253 was statistically

252 d adenomatous polyps, and 5.7% had 1 or more serrated polyps removed.

253 ng analysis showed subsets of fibroblasts in serrated polyps that express genes that regulate matrix

254 n of the MMP inhibitor reduced the number of serrated polyps that formed in the HBUS mice.

255 World Health Organization propose assigning serrated polyps to categories of hyperplastic polyps, tr

256 und in the distal colon, while 80.5 % of all serrated polyps were detected in the proximal colon.

257 on varied significantly between adenomas and serrated polyps were sex (P < 0.001), use of estrogen-on

258 ffers a higher detection rate of significant serrated polyps when compared to standard colonoscopy.

259 The risk of CRC in patients with multiple serrated polyps who do not meet the criteria for serrate

260 d pathological data were reviewed, comparing serrated polyps with adenomas and hyperplastic polyps in

261 definition white light colonoscopy regarding serrated polyps' detection.

262 (P = 0.05 among adenomas and P < 0.001 among serrated polyps), postmenopausal estrogen-only therapy (

263 among adenomas), and obesity (P = 0.01 among serrated polyps).

264 rols, 489 cases with adenoma, 401 cases with serrated polyps, and 188 cases with both polyp types.

265 CRC begins as adenomatous or serrated polyps, and in particular as advanced precursor

266 of colorectal polyps, including adenomas and serrated polyps, and single-nucleotide polymorphisms (SN

267 tion of categories and molecular features of serrated polyps, as well as endoscopic detection and ris

268 The importance of serrated polyps, as well as their surveillance intervals

269 investigated whether patients with multiple serrated polyps, but not meeting the World Health Organi

270 67 was significantly associated with sessile serrated polyps, but this association was opposite of th

271 detection and removal of adenomas; however, serrated polyps, particularly sessile serrated polyps (S

272 Patients with serrated polyps, particularly SSLs and traditional serra

273 l cancer (CRC) can arise from adenomatous or serrated polyps, which differ in their detection rate an

274 ve 1 or more adenomas, advanced adenomas, or serrated polyps.

275 We studied CRC risks associated with serrated polyps.

276 these lesions using current terminology for serrated polyps.

277 the membrane) rapidly developed large cecal serrated polyps.

278 he intestine of mice promotes development of serrated polyps.

279 of mice promoted development of small cecal serrated polyps.

280 h these changes contribute to development of serrated polyps.

281 mmatory factors contribute to development of serrated polyps.

282 polyposis: 3.28, 95% CI, 2.16-4.77; multiple serrated polyps: 2.79, 95% CI, 2.10-3.63; P = .50).

283 vs 0.07) and all neoplastic (adenomatous and serrated) polyps (1.50 vs 1.14) per procedure.

284 esults in the decay and disappearance of the serrated response.

285 variety of intriguing phenotypes, including serrated rosette leaves, irregular flowers, floral organ

286 ith FIT (P=0.004); the rates of detection of serrated sessile polyps measuring 1 cm or more were 42.4

287 kades with unique and easily distinguishable serrated shape electrical signals.

288 ndensation frosting process on surfaces with serrated structures on the millimeter scale, which is di

289 SSLs, the most common premalignant serrated subtype, and are found in up to 15% of average-

290 The key enabling feature is the serrated teeth along the edges across an inclined gap as

291 To investigate the effectiveness of serrated teeth on the formation of multiple fiber bundle

292 The sharp points on the serrated teeth provide favorable charge dissipation poin

293 ing the antorbital and mandibular fenestrae, serrated teeth, and closed lower temporal bar.

294 ies, suggesting a crucial role in supporting serrated teeth.

295 A serrated tensile response corresponding to stress oscill

296 a wing-like planform, the fossil preserves a serrated trailing edge that is reinforced by novel carti

297 d whole-exome sequencing of both MSS and MSI serrated tumors derived from these mouse models revealed

298 ed from these mouse models revealed that all serrated tumors developed oncogenic WNT mutations, predo

299 ggressive CRCs harbor the characteristics of serrated tumors, suggesting that initiation through this

300 s, KRAS mutations were found mainly in a non-serrated variant.