ライフサイエンスコーパス: serum

1 0 fg/mL biotinylated bovine serum albumin in serum.

2 bel-free sensor for AIV detection in chicken serum.

3 irus, can be treated with convalescent-phase serum.

4 an antibody purified from anti- Ab-54149 EPS serum.

5 mount of HSV-specific IgG in the transferred serum.

6 ly applied to the detection of CD56 in human serum.

7 rthermore 58 glycans are enriched from human serum.

8 tryptophan degradation metabolites in mouse serum.

9 tissue and were consistently detected in the serum.

10 ol of KP that was restored by adding healthy serum.

11 Serum 25(OH)D at age 1 y is inversely associated with ch

12 r and there was a trend (p < 0.10) for lower serum 25(OH)D concentrations in the Above group.

13 Mean serum 25(OH)D concentrations were lower in populations l

14 We quantified serum 25(OH)D in samples obtained at age 1 y from 306 pa

15 All participants (n = 151) underwent serum 25-hydroxy vitamin D measurement and completed a q

16 Higher serum 6-bromotryptophan has been associated with lower r

17 ncreased rates of Ig production and elevated serum Ab concentrations elicited by primary immunization

18 , hs-CRP remained a significant predictor of serum ADMA (P < 0.001).

19 nificant predictor of increased salivary and serum ADMA levels.

20 < 0.001) were significantly associated with serum ADMA, whereas in a multivariate model, hs-CRP rema

21 dr2(-/-) mice had elevated liver weights and serum alanine transferase values.

22 eting highly abundant proteins such as human serum albumin (>10(10) more abundant than cTnI).

23 mug/mL) after passive adsorption and bovine serum albumin (BSA) as a blocking agent generated a mode

24 GSTP), human serum albumin (HSA), and bovine serum albumin (BSA) as model target proteins.

25 eling of a yeast proteome spiked with bovine serum albumin (BSA) over a 10-fold dynamic range.

26 glutathione S-transferase pi (hGSTP), human serum albumin (HSA), and bovine serum albumin (BSA) as m

27 antly expressed extracellular protein, human serum albumin (HSA), inhibits alphaS oligomer (alphaS(n)

28 The ability to detect miRNA-21 in human serum albumin and bovine serum albumin was almost identi

29 S, combining elevated hsCRP and ESR with low serum albumin and iron], and serum interleukin (IL) 1bet

30 es of the enrichment step from spiked bovine serum albumin digests were >80% for the commercial Fe-IM

31 n selective binding to the transport protein serum albumin in PBS buffer at ambient conditions.

32 rtisol solutions in a complex matrix (bovine serum albumin in phosphate buffered saline) is also demo

33 tion limit of ~110 fg/mL biotinylated bovine serum albumin in serum.

34 t miRNA-21 in human serum albumin and bovine serum albumin was almost identical to that in PBS.

35 h four reference molecules (dopamine, bovine serum albumin, glucose and elongated peptide) was neglig

36 such as glutathione S-transferase pi (GSTP), serum albumin, or Keap1.

37 In the presence of serum albumin, the potency of JMS-053 as an in vitro inh

38 blood was removed and replaced with 5% human serum albumin.

39 known to exhibit high binding affinities to serum albumin.

40 regulates pendrin, as well as the effect of serum aldosterone and potassium on this response, we mea

41 d ending values of plasma renin activity and serum aldosterone were 6.8 vs. 5.5 ng/mL/h (p = 0.002) a

42 ed GC-1 diet for 2 and 4 weeks had decreased serum alkaline phosphatase but increased serum transamin

43 ysis showed that hypocalcemia was related to serum ALP.

44 This serum also induced bacterial killing in opsonophagocytos

45 n, reduced liver inflammation, and decreased serum ALT/AST levels.

46 kly oxidized by the copper-containing bovine serum amine oxidase.

47 experienced hypotension, and 5 had elevated serum aminotransferases, reinforcing the need for vigila

48 , ferritin (OR = 4.20, CI = 1.40-12.65), and serum amyloid P (OR = 3.05, CI = 1.16-8.01) were associa

49 T cells were analyzed by flow cytometry, and serum amyloid proteins (SAA) were analyzed by quantitati

50 Serum analysis revealed significant reduction in key bio

51 Br, Rb, Sr, Mo, I, Cs, and Ba) in 10 muL of serum and 12 elements (Mg, S, Mn, Fe, Co, Cu, Zn Se, Br,

52 ed to provide robust quantification in human serum and are shown to be compatible with each of the mo

53 evealed high titers of IgG autoantibodies in serum and cerebrospinal fluid directed against the nucle

54 LC-MS/MS), or animal-origin deconjugase (rat serum and chicken pancreas) (AE-LC-MS/MS) was used in th

55 h member of this library for growth in human serum and discovered 178 mutants with significant abunda

56 dule, and acquired antigens via convalescent serum and Fc receptors.

57 ice with high RNA copy numbers detectable in serum and feces.

58 Chorein upregulates the serum and glucocorticoid inducible kinase SGK1.

59 long-term persistence of Vi-specific IgG in serum and IgG(+) antibody-secreting cells in bone marrow

60 ower levels of gamma-glutamyl transferase in serum and lower LSMs than adults with the Pi*ZZ variant,

61 tethered antibody formats from both in vitro serum and pharmacokinetic study samples.

62 linical laboratories to quantify proteins in serum and plasma samples.

63 or C-reactive protein (CRP) determination in serum and preterm neonatal plasma samples with sepsis su

64 Mycology Reference Laboratory received 1,267 serum and respiratory samples from 719 critically ill UK

65 more, we examined the hormone levels both in serum and saliva during transplantation in 7 postmenopau

66 hly significant positive correlation between serum and salivary PCT values to clinical attachment lev

67 tes numerous small molecules in the maternal serum and the brains of fetal offspring.

68 g in decreased target cell burden, decreased serum and tissue-bound autoantibodies, and increased DSG

69 al growth factor-A secretion was measured in serum and/or cholangiocyte supernatant.

70 was obtained during the detection of CRP in serum, and a large working range (1 ng/mL - 100 mug/mL)

71 y four different nucleases, bovine and human serum, and human urine.

72 dated using spiked samples (tap water, blood serum, and saliva) and bacteria media (blank broth, Stap

73 ein concentrations in protein-spiked buffer, serum, and urine in seconds with excellent sensitivity (

74 arious body fluids, including urine, saliva, serum, and whole blood.

75 eat-labile toxin [LT(R192G)] elicited strong serum anti-CfaE and anti-LTB antibody responses and conf

76 reinfection with SARS-CoV-2 is and how long serum antibodies and virus-specific T cells persist afte

77 of lectins, anti-ganglioside antibodies, and serum antibodies of GBS patients.

78 01), splenomegaly (P < .0001), and increased serum antibody titers (P < .01), whereas control mice di

79 re workers with negative SARS-CoV-2-specific serum antibody titers showed SARS-CoV-2-specific IgA in

80 bitor attenuated lupus pathology by reducing serum antinuclear autoantibodies, dsDNA titers, and the

81 cal nonadherence to adjuvant tamoxifen using serum assessment and to examine its effects on short-ter

82 ncrease in indoxyl sulfate concentrations in serum associated with a stronger impairment in cognition

83 se events) and pharmacokinetics (assessed by serum atezolizumab concentrations).

84 included 10 studies of the use of autologous serum-based eye drops for severe dry eye disease and 4 s

85 y hospital from 2012-2017 who had at least 2 serum BDG determinations throughout the episode of funge

86 properties, which correlated with changes in serum bile acid profile.

87 cy (ICP), a disorder characterised by raised serum bile acids, are at increased risk of developing ge

88 Postoperative serum bilirubin and prothrombin time-international norma

89 The present study assessed the dynamics of serum biochemical parameters in a model of experimental

90 Cluster analysis identified 4 serum biomarker-based clusters, 3 of which (clusters B,

91 On-chip microarray analysis of serum biomarkers (e.g., cardiac troponin I) afforded up

92 We evaluated serum biomarkers in 149 individuals; 77 (52%) pre-SOT an

93 We assessed the diagnostic values of serum biomarkers in the differential diagnosis between F

94 We aimed to identify serum biomarkers of Crohn's disease and ulcerative colit

95 Higher concentrations of serum biomarkers were associated with the development of

96 Viral load was quantified in acute-phase serum by real-time reverse transcription polymerase chai

97 est was compared with that of measurement of serum C-reactive protein (CRP) and fecal calprotectin.

98 ing and reduces lung collagen deposition and serum C3M, a marker of IPF disease progression.

99 he calcium-sensing receptor (CaSR) regulates serum calcium concentrations.

100 ee made 1 strong recommendation for baseline serum calcium testing, 13 conditional recommendations, a

101 -IgE complexes and free omalizumab levels in serum (chi(2) = 65.84; degrees of freedom [df] = 2; P <

102 This study confirms that serum chymase levels are associated with DHF/Severe deng

103 psilonRI binding and enhanced CD23-dependent serum clearance.

104 he 19 currently available biomarkers only 4 (serum Coll2-1 NO2, CS846, COMP and urinary CTXII) were c

105 urs) in mice, suggesting possible binding to serum components.

106 (SNPs) with log-transformed FGF21 and FGF23 serum concentrations adjusted for age, sex and principal

107 Serum concentrations of arginine, ornithine, polyamines,

108 Serum concentrations of atezolizumab were above the targ

109 the highest quintile had significantly lower serum concentrations of fT4, TT4, fT3, and TT3 [absolute

110 Findings suggest that serum concentrations of high-sensitivity C-reactive prot

111 ntal treatment was associated with decreased serum concentrations of MBL and CRP and increased serum

112 Serum concentrations of n-3 PUFAs were significantly hig

113 , we showed that IL-6 and C-reactive protein serum concentrations were higher in patients who were ho

114 DART molecule serum concentrations were well above those considered ad

115 or AH50 less than median, impaired in vitro serum control of KP that was restored by adding healthy

116 tors of clinical responder status were lower serum creatinine and KCCQ-OS scores and treatment assign

117 roposed a new predictive model that combines serum creatinine levels and maximum liver function capac

118 Serum creatinine levels tended to mildly increase (3% be

119 ata, including admission, peak, and terminal serum creatinine, and biopsy data when available to diff

120 age and Sequential Organ Failure Assessment, serum CXCL10/IP-10 (P = 0.047) and GM-CSF (P = 0.050) we

121 Serum cystatin C (CysC; subdistribution hazard ratio [SH

122 Upon serum deprivation, a subset of AEs pre-marked by the act

123 vel was significantly upregulated in patient serum discriminating from healthy individuals and closel

124 rucial in selecting appropriate convalescent serum donors.

125 Serum EBOV-neutralizing and binding antibodies using wil

126 To investigate the potential threat of serum escape mutant viruses to humans and poultry, the i

127 report here that in the presence of ruminant serum, exogenously added polyamines are quickly oxidized

128 Serum extracellular vesicles from 74 individuals presume

129 ys that detected M. tuberculosis peptides in serum extracellular vesicles from TB patients.

130 ly Biomarkers of AMD (EBAMD) study evaluates serum factors that protect foveal MPOD architecture in C

131 Each data set included measures of serum ferritin (SF), vitamin A, zinc, and CRP measured u

132 Her serum ferritin was higher than 21,000 ng/mL and transfer

133 hropometry; nutritional biomarkers including serum ferritin, soluble transferrin receptor, retinol-bi

134 e allergen-specific antibodies and patients' serum followed by mass spectrometric analyses.

135 ApoA-IV levels were decreased in serum from allergic patients compared to healthy control

136 trikingly, BMP4 concentrations are higher in serum from HGPS vs. age-matched mice.

137 ynthase kinase 3 (PI3K/GSK3) signaling, with serum-glucocorticoid kinase 1 (SGK1), an inhibitor of gl

138 mTORC1 and mTORC2-specific serum/glucocorticoid-regulated kinase 1 (SGK1) are const

139 this prospective study, we aimed to define a serum glycomic signature in the first week after liver t

140 cles were efficiently neutralized by diluted serum (>:640) from recently recovered COVID-19 patients

141 mesothelin-expressing tumors and has a short serum half-life.

142 thy in 64.7%, GADA (>=35 U/mL) in 54.1%, and serum HbA1c > 48 mmol/mol in 94.3% of the individuals.

143 Median serum HBsAg half-life (t(1/2)) was estimated as 1.3 [0.9

144 Undiluted pooled human serum (HS) and five different commercial preparations of

145 sociation between periodontal conditions and serum hsCRP levels.

146 significant increase of SARS-CoV-2-specific serum IgA and IgG titers after symptom onset.

147 The workflow was tested using serum IgA1 from healthy subjects.

148 gnificantly reduced Th2 cytokine production, serum IgE levels, and airway hyperreactivity.

149 s milder and characterized by a fast rise in serum IgG and neutralizing antibodies.

150 Serum IgG testing against potential antigens associated

151 Whereas overall RBD-specific serum IgG titers waned with a half-life of 49 days, nAb

152 isplayed reduced efficacy in the presence of serum IgG.

153 sinophils, goblet cell hyperplasia, elevated serum Igs, and induction of Th2 cytokines.

154 Serum IL-27 levels continued to rise during infection.

155 At best response, median serum immunoglobulin M declined from 3,520 to 821 mg/dL,

156 Neural activity after serum incubation was assessed in mouse slices using mole

157 Aberrant serum-induced ciliary resorption and cold-induced depoly

158 serum Klotho levels had significantly higher serum Inhibin B and total sperm count than men with the

159 nd ESR with low serum albumin and iron], and serum interleukin (IL) 1beta were positively associated

160 patients with high blood eosinophils or low serum interleukin-18 response are potential subgroups fo

161 howed a significant association between cord serum interleukin-7 at birth and the trajectories of chi

162 ved a U-shaped association between admission serum ionized calcium and in-hospital AKI, with nadir in

163 pital AKI, with nadir in-hospital AKI was in serum ionized calcium of 5.00-5.19 mg/dL.

164 ficiency virus (HIV) infection, and elevated serum iron.

165 Concentration of alpha-amylase in human serum is a key indicator of various pancreatic ailments

166 A specific to SARS-CoV-2 (IgA) in saliva and serum is needed to complement tests that detect immunogl

167 d total sperm count than men with the lowest serum Klotho concentrations.

168 revealed that infertile men with the highest serum Klotho levels had significantly higher serum Inhib

169 ve demonstrated that systemic restriction of serum l-Met, either via partial dietary restriction or w

170 Antihuman lymphocyte serum (L1S1) antibody completely prevented acute GVHD.

171 Serum lactate (LA) may be elevated in patients with CLD

172 cells.CONCLUSIONThe association between IL-6 serum levels and the impairment of cytotoxic activity su

173 We sought to determine whether baseline IL-6 serum levels can predict the need for IMV and the respon

174 (iii) increased circulating cell-free mtDNA serum levels in both patients with biallelic or with het

175 ues for insulin and also measured tissue and serum levels in several carefully phenotyped human cohor

176 liver disease at time of hospital admission, serum levels of albumin and sodium, and white blood cell

177 Increased serum levels of IgM-anti-FceRIalpha are common in patien

178 emur in female N-ERalphaKO along with higher serum levels of insulin-like growth factor (IGF)-1 as we

179 Serum levels of interferon alpha were significantly lowe

180 concentrations of MBL and CRP and increased serum levels of SIRT1.

181 We show that serum levels of soluble scavenger receptor-A (sSR-A) are

182 in both adipose tissue and liver as well as serum levels were strongly associated with markers of in

183 fector cell sensitization, reduced total IgE serum levels, protected mice from passive and active IgE

184 ies such as Streptomyces chromofuscus PLD or serum lipase.

185 prevalence of adolescents with one abnormal serum lipid component was 43.2% and was significantly di

186 NASH patients had higher serum LPS and hepatocytes LPS localization than controls

187 mutations in SLC39A8 result in undetectable serum manganese (Mn) and a Congenital Disorder of Glycos

188 the interference from free receptors in the serum matrix.

189 Here, we conduct machine learning of serum metabolic patterns to detect early-stage LA.

190 The serum metabolome contains a plethora of biomarkers and c

191 Serum miR-1 levels had inverse correlations with sputum

192 Among these, serum miR-1260b level was significantly upregulated in p

193 Serum miR-375 was significantly lower in the peritoneal

194 We recently reported that serum N-glycans were altered in mice displayed depressiv

195 After the second immunization, serum neutralizing activity was detected in all the part

196 Geometric mean titres of SARS-CoV-2 serum-neutralizing antibodies on day 43 were 0.7-fold (1

197 Serum NMDAR antibodies have been reported in a minority

198 Viremia in serum of Ad AdrA wt-treated mice was reduced significant

199 owed low levels of glycine and serine in the serum of MacTel patients.

200 -malignant MG was identified in the baseline serum of participants of RIISC.

201 senoic acid were significantly higher in the serum of women with SCH when compared to women with a no

202 n within controlled periods, using 10 muL of serum only.

203 % of the total protein in 1:4 diluted human serum or 0.024 wt % of the total protein from breast can

204 Detectable serum or plasma cryptococcal antigen (CrAg) precedes sym

205 Therefore, we examined serum PACAP and associated PAC1R genotype in a cohort of

206 Serum-PC ALA was inversely related to all-cause mortalit

207 ed for known clinical predictors showed that serum-PC EPA at the time of STEMI was inversely associat

208 r data showed higher prevalences of positive serum PCA (P = 0.057), hypergastrinemia (P = 0.062) and

209 Linear regression model showed serum PCT to be a significant predictor for CAL.

210 one cycle, and, modulation of cycle-specific serum pentraxin 3 levels over various cycles indicate st

211 associations of repeated pre- and postnatal serum PFAS concentrations with adolescent adiposity and

212 and also produces similar T(1) relaxivity in serum phantoms at 4.7 T and 37 degrees C.

213 , we incorporated VRC01 neutralization using serum pharmacokinetics (HVTN 104) and in vitro pharmacod

214 eloped moderate to severe hypophosphataemia (serum phosphate < 0.6 mmol/L).

215 reased urinary phosphate excretion maintains serum phosphate levels within the normal range, thus pro

216 nd relevant cytokine levels were assessed in serum, plasma and BAL.

217 and uninfected subjects, and a wide range of serum/plasma antibody levels was delineated in infected

218 elines recommend routine kidney function and serum potassium testing within 30 days of initiating ACE

219 ithout significant changes in BP, weight, or serum potassium.

220 Serum progesterone level was significantly (p = 0.026) e

221 ed systemic inflammation with high levels of serum proinflammatory cytokines, inflammatory infiltrate

222 thyretin (TTR) is an abundant homotetrameric serum protein and was selected here for engineering high

223 Heating lactoferrin and milk serum proteins together accelerated the loss of bacterio

224 g the depth and complexity of the plasma and serum proteomes.

225 ion of biomarkers in biological samples, and serum proteomics is a useful and minimally invasive meth

226 sitive method for measuring NfL in plasma or serum, provide translational tools to make development o

227 There were 75 men (median age, 69 y; median serum PSA, 3.69 mug/L) with 232 metastatic nodes less th

228 Serum receptor activator of nuclear factor kappa B ligan

229 The properties of autologous serum remain after lyophilization.

230 mL and >10 ng/mL were achieved in buffer and serum, respectively.

231 s estimated the association between baseline serum retinol quintile and overall and site-specific can

232 While the serum RSV G antibody repertoires in the 2 groups were si

233 Serum RSV-neutralizing antibodies and anti-RSV fusion im

234 t sera (n = 31), CSFs (n = 11), longitudinal serum samples (n = 15), and using mAbs (n = 14) generate

235 ofiling in both brain (n = 109) and matching serum samples (n = 566) to identify differentially expre

236 Sera from 763 representative subjects with serum samples available at all 3 ages were analyzed for

237 All the subjects were adults, and serum samples collected during the discharge were tested

238 Using sequential serum samples collected up to 94 d post onset of symptom

239 and dried chemicals on the all-in-one chip, serum samples containing the target virus RNA were simpl

240 was measured by using Luminex technology in serum samples from 146 patients with severe AD (median E

241 identify candidate chemicals of interest in serum samples from 83 women FFs and 79 women office work

242 Serum samples from a total of 49 documented consecutive

243 In addition, serum samples from healthy volunteers vaccinated with a

244 We assessed sensitivity using 128 serum samples from symptomatic PCR-confirmed coronavirus

245 pletion of TRIM72 antibodies from these same serum samples rescues sarcolemmal repair capacity.

246 Analysis of PLA2R-AB in longitudinal serum samples revealed seropositivity in 44% (59 out of

247 Saliva and serum samples were also collected.

248 Serum samples were analyzed by gliadin antibody enzyme-l

249 Donor serum samples were evaluated by indirect immunofluoresce

250 Serum samples were used to measure the levels of tumor n

251 In sequential pre- and post-COVID-19 serum samples, we confirmed autoAb seroconversion.

252 s also evaluated to detect uric acid in real serum samples.

253 between 108.84% and 172.50% (n = 3) in human serum samples.

254 monstrated, measuring miRNA-492 in undiluted serum samples.

255 tforms using a set of 223 well-characterized serum samples.

256 he fast, accurate assays of 100-fold diluted serum samples.

257 1 concentrations (AUC = 0.82, P = 0.017) and serum Sdc-1 concentrations (AUC = 0.84, P = 0.006) were

258 Patients with lean NAFLD had higher serum secondary BA and FGF19 levels and reduced 7-alpha-

259 d 11 Progressive Disease) were evaluated for serum SEVs size, concentration and screened for 95 oncom

260 nimal sera have many disadvantages including serum sickness, batch-to-batch variation in quality and

261 ese results suggest the potential utility of serum sphingolipids as cholesterol-independent markers o

262 a shotgun-proteomics workflow and applied to serum spiked with the sulfopeptides before protein depho

263 We measured serum sRAGE level at acute hospitalization and examined

264 duced in differentiated VSMCs in response to serum stimulation.

265 fonates (PFSAs) were enriched in dosed mouse serum, suggesting in vivo transformation of sulfonamide

266 Serum t-tau, Nf-L, and GFAP predict the development of s

267 prodrugs showed excellent stability in human serum (t(1/2) > 12 h) and potent activation of Vgamma9/V

268 available amylase measurements employed with serum tests.

269 Serum thromboxane B2 (sTXB2), a validated biomarker of p

270 xpression of caspase-8, TNFR1, and increased serum TNF-alpha.

271 tration partially attenuated the increase of serum TNF-alpha.

272 ion of multiplex cardiac biomarkers in human serum to expedite medical decisions for enhanced patient

273 re significantly impacts EV yield from human serum, together with the presence of lipoprotein and pro

274 Whole apple (WA) consumption decreased serum total (WA: 5.89 mmol/L; CB: 6.11 mmol/L; P = 0.006

275 Serum toxin A- and B-specific neutralizing antibodies we

276 sed serum alkaline phosphatase but increased serum transaminases compared with KO alone.

277 Levels of serum transaminases were retrieved from 444,642 particip

278 C) activation symptoms and elevated baseline serum tryptase level (MCAS-T) may not necessarily have a

279 A baseline serum tryptase level within the upper normal range (8-11

280 f ILC2s, which was independent from atopy or serum tryptase levels.

281 CB(2) -R activation also decreased serum tumor necrosis factor-alpha levels and improved ca

282 sian populations to identify 10 new loci for serum urate levels.

283 is a transcription factor that may regulate serum urate via the pentose-phosphate pathway and MRPS7

284 ; CB: 159.4 ng/mL; P = 0.028), and increased serum uric acid (WA: 341.4 mumol/L; CB: 330 mumol/L; P =

285 This first GWAS of serum uric acid in continental Africans identified three

286 d kidneys, reduced oxidative stress, lowered serum uric acid level, reduced glomerular hyperfiltratio

287 and renal function plays a critical role in serum uric acid levels.

288 biased approach to identify loci influencing serum uric acid.

289 ntibodies (TPOAb and TgAb, respectively)] in serum using electrochemiluminescence assays.

290 n study 1, mean change (baseline to 3 mo) in serum vitamin D3 was -0.1 ng/mL in the placebo group and

291 In addition, high miR-1260b expression in serum was correlated with radiological tail-like pattern

292 Overall, saliva with 5% human serum was optimal for replicating subgingival microbiome

293 Metabolomic profiling of fasting serum was performed using a global, untargeted approach.

294 A series of seven peaks in dosed mouse serum was tentatively identified as sulfonimide dimers t

295 ients with CXCL12 levels above the median in serum were more prone to develop ADAs (aHR = 2.329 [1.10

296 of 10(5) exosomes muL(-1) directly in human serum, when performing the immunomagnetic separation wit

297 n was measured for mammalian cell lysate and serum, which led to estimates of low-mM ribose in a HeLa

298 The sensors are able to measure PSA in serum with a dynamic range between 0.26 and 62.5 ng/mL (

299 tissue sensitive to metabolic stress such as serum withdrawal and restrictive feeding.

300 ion than controls, which was correlated with serum zonulin and phosphorylated nuclear factor-kappaB e