ライフサイエンスコーパス: serum calcium

1 ns occur in response to prolonged changes in serum calcium.

2 e group had at least one elevated measure of serum calcium.

3 us, low hemoglobin level, and high corrected serum calcium.

4 ncentrations, decreased PTH and no change in serum calcium.

5 ers are responsible for abnormalities in the serum calcium.

6 Henle to sense and respond to alterations in serum calcium.

7 uctions in parathyroid hormone fail to lower serum calcium.

8 ium diet, PTH was suppressed, despite normal serum calcium.

9 centrifuge sediment increased along with the serum calcium.

10 TH play a critical role in the regulation of serum calcium.

11 GS was required because of her low levels of serum calcium.

12 tification factors haemoglobin and corrected serum calcium.

13 analysis of the ePTH patients revealed that serum calcium 1-week after surgery was predictive of rec

14 changes in intestinal calcium absorption and serum calcium, 1alpha,25-dihydroxyvitamin D also repress

15 longitudinal study of the effects of GBP on serum calcium, 25-hydroxy-vitamin-D (vitamin D), and par

16 2)Ca(serum) ratio positively correlated with serum calcium, 25-hydroxyvitamin D and alkaline phosphat

17 In EPIC, nonalbumin-adjusted total serum calcium (a proxy of free calcium) was not associat

18 Serum calcium and 1,25-dihydroxyvitamin D(3) levels were

19 administration was associated with increased serum calcium and a lack of increase in body weight in a

20 Serum calcium and BMD were measured in NHANES laboratori

21 calcitriol (12.5 microg/d) which normalized serum calcium and improved his rickets.

22 Treatment reduces serum calcium and improves symptoms, at least transientl

23 his was accompanied by significantly reduced serum calcium and increased PTH levels in patients with

24 pic and phosphaturic hormones, and urine and serum calcium and inorganic phosphorus in mice in which

25 As anticipated, parathyroidectomy reduced serum calcium and intact parathyroid hormone levels.

26 Higher serum calcium and lower PTH levels were demonstrated in

27 mice exhibited hypercalciuria and had lower serum calcium and markedly increased serum PTH levels.

28 -heritability (rg = 0.191, P = 0.03) between serum calcium and migraine headache, indicating that the

29 High levels of serum calcium and OPG are significantly associated with

30 ive factors for hypocalcemia, measurement of serum calcium and parathyroid hormone (PTH) levels, and

31 Sost KO and WT mice had similar serum calcium and parathyroid hormone concentrations.

32 r can cause an abnormal relationship between serum calcium and parathyroid hormone response, as is ty

33 ther markers of mineral metabolism including serum calcium and phosphate showed no significant associ

34 nd meat protein intakes, height, weight, and serum calcium and phosphorus concentrations all independ

35 condary hyperparathyroidism by correction of serum calcium and phosphorus concentrations and the admi

36 no significant between-group differences in serum calcium and phosphorus concentrations or in urine

37 sphocalcic product (the product of the total serum calcium and phosphorus concentrations).

38 with the patients' clinical characteristics, serum calcium and phosphorus concentrations, and other b

39 Serum calcium and phosphorus levels were not statistical

40 nalogue, appears to lessen the elevations in serum calcium and phosphorus levels, as compared with ca

41 ndex (LVMI), serum C-reactive protein (CRP), serum calcium and phosphorus, and erythropoietin resista

42 mean ratio of urinary calcium to creatinine, serum calcium and phosphorus, or change in iron status (

43 t parathyroid hormone and elevated levels of serum calcium and phosphorus, situations in which inject

44 abolism, particularly high concentrations of serum calcium and phosphorus, were associated with incre

45 the low potency of this analog in increasing serum calcium and phosphorus.

46 in darker-skinned children), and, inversely, serum calcium and phosphorus.

47 calcet for achieving long-term reductions in serum calcium and PTH concentrations in primary hyperpar

48 idectomy results in greater normalization of serum calcium and PTH levels and significantly improves

49 hyroid tumour development, and elevations in serum calcium and PTH, were similar in males and females

50 notably, a shift in the relationship between serum calcium and PTH.

51 ice exhibit a much wider range of values for serum calcium and renal excretion of calcium than we obs

52 (KO/TG mice) results in the normalization of serum calcium and rescue of rickets.

53 UV irradiation of DBP(+/+) animals restored serum calcium and serum 25(OH)D while the same treatment

54 1, 25 dihydroxy vitamin D3, FGF23, serum calcium and urinary phosphorus were significant de

55 completing an allelic series with respect to serum calcium, and alone are responsible for a symptom b

56 in Red and von Kossa stains, by depletion of serum calcium, and by uptake of calcium and phosphate by

57 arction was weighted by its association with serum calcium, and estimates were combined using an inve

58 hosphorus, absence of diabetes, younger age, serum calcium, and female gender.

59 roid hormone, increased vitamin D, increased serum calcium, and normalization of bone markers such as

60 adjusting for age, gender, diabetic status, serum calcium, and phosphorus (P < 0.0001).

61 measurement of hemoglobin, serum creatinine, serum calcium, and serum free light chain levels; serum

62 order, the magnitude of the deviation of the serum calcium, and the severity of symptoms.

63 genase, low serum hemoglobin, high corrected serum calcium, and time from initial RCC diagnosis to st

64 creatinine, C-reactive protein, electrolyte, serum calcium, and troponin T levels, were within normal

65 in parathyroid hormone secretory control by serum calcium, as had been hypothesized.

66 that the analogue 4 significantly increases serum calcium at dose levels similar to 1alpha,25-(OH)2D

67 ms (SNPs)) that independently contributed to serum calcium at genome-wide significance which we appli

68 Very severe hypocalcemia (serum calcium below 6.5 mg/dL [1.63 mmol/L] or emergent

69 cemia was defined as total albumin-corrected serum calcium below 7.5 mg/dL (1.88 mmol/L) or a primary

70 iazide diuretics were associated with higher serum calcium (beta [SE], 0.051 [0.0092]; P < .001) and

71 CaSR gene SNP rs1801725 was associated with serum calcium but not with risk of diabetes.

72 efined as the multiplication of preoperative serum calcium by preoperative parathyroid hormone (PTH).

73 in EDTA injection alone, such as decrease in serum calcium (Ca), increase in urine Ca, or toxicity to

74 No differences in serum calcium (Ca), inorganic phosphate (Pi) or 25-hydro

75 started with morphological and biochemical (serum calcium, calcitriol) stabilization.

76 ied in genome- and epigenome-wide studies of serum calcium (CASR), serum calcium-related risk of CHD

77 odels, while not causing toxicity related to serum calcium chelation.

78 d compression), hypercalcemia (symptoms or a serum calcium concentration > or = 12 mg per deciliter [

79 2.31, 2.05-2.60; p<0.0001), and raised total serum calcium concentration (1.43, 1.21-1.69; p<0.0001),

80 ozygous carriers showed significantly higher serum calcium concentration (P=0.01) and a trend for hig

81 pinal cord compression, and hypercalcemia (a serum calcium concentration above 12 mg per deciliter [3

82 the CYP24A1-associated locus correlates with serum calcium concentration and a number of nephrolithia

83 ne as evidenced by a greater increase of the serum calcium concentration and urine deoxypyridinoline

84 r, and safety measures of renal function and serum calcium concentration assessed every 3 months.

85 either unable or only slightly able to raise serum calcium concentration but are nevertheless able to

86 ication of variation in CASR that influences serum calcium concentration confirms the results of earl

87 dministration and the subsequent increase in serum calcium concentration decrease parathyroid hormone

88 ium and active vitamin D while maintaining a serum calcium concentration greater than or the same as

89 f this study was to test the hypothesis that serum calcium concentration is positively and independen

90 Uncorrected serum calcium concentration is the first mineral metabol

91 rathyroidism has been described in which the serum calcium concentration is within normal range but p

92 Abnormalities in serum calcium concentration may have profound effects on

93 At base line, the mean (+/-SE) serum calcium concentration was 10.7+/-0.2 mg per decili

94 have assessed the association of uncorrected serum calcium concentration with clinical outcomes.

95 who did not undergo surgery had no change in serum calcium concentration, urinary calcium excretion,

96 kidney plays a major role in maintenance of serum calcium concentration, which must be kept within a

97 ctions of the native hormone without raising serum calcium concentration.

98 nitiates an endocrine cascade that regulates serum calcium concentration.

99 isk of kidney stone disease is by increasing serum calcium concentration.

100 f kidney stone disease by elevating adjusted serum calcium concentrations (beta=0.12 mmol/L); WHR med

101 Serum calcium concentrations also decreased by 5 to 10%

102 or without symptoms led to normalization of serum calcium concentrations and a mean (+/-SE) increase

103 um-based binders led to significantly higher serum calcium concentrations and an increased incidence

104 go parathyroid surgery include monitoring of serum calcium concentrations and bone density.

105 However, the roles of serum calcium concentrations and vitamin D status have y

106 Our prior work indicated lower serum calcium concentrations are associated with longer

107 e-aged population of European-ancestry where serum calcium concentrations are likely stable and chron

108 th the Dunnett procedure was used to compare serum calcium concentrations at different time points af

109 Sevelamer, however, maintained serum calcium concentrations closer to the lower end of

110 Serum calcium concentrations lowered from 9.46 +/- 0.02

111 and Cdc73(L/L)/PTH-Cre mice had higher mean serum calcium concentrations than wild-type littermates,

112 GWAS of serum calcium concentrations was performed in 20 611 ind

113 Higher adjusted serum calcium concentrations were also associated with a

114 dicates that visceral adipose depots elevate serum calcium concentrations, resulting in increased ris

115 Total serum calcium concentrations, which had ranged from 3.5

116 he calcium-sensing receptor (CaSR) regulates serum calcium concentrations.

117 ] and accounted for 0.54% of the variance in serum calcium concentrations.

118 ese mutations had hypercalciuria even at low serum calcium concentrations.

119 While serum calcium correction effectively treats papilledema,

120 hundred ninety-six inpatients with available serum calcium data obtained before and after gadodiamide

121 serum PTH levels, regardless of high or low serum calcium, demonstrated that PTH/PTH1R signaling exe

122 esults: Forty-one of the 127 men (32%) had a serum calcium drop, and 6 (5%) developed clinical hypoca

123 was then maintained for another 18 wk unless serum calcium exceeded 11.5 mg/dL or Ca x P product exce

124 76 226 participants not contributing to the serum calcium genome-wide association study.

125 s (recurrence < 12 months after nephrectomy, serum calcium > 10 mg/dL, hemoglobin < lower limit of no

126 us criteria were examined, age <50 (P<0.01), serum calcium >11.3 mg/dL (P < 0.01), and hypercalciuria

127 (< lower limit of normal), high "corrected" serum calcium (> 10 mg/dL), and absence of prior nephrec

128 Elevated serum calcium has been associated with a variety of meta

129 Serum calcium has been associated with cardiovascular di

130 RF analysis of serum biomarkers identified serum calcium, hemoglobin and red blood cell (RBC) count

131 ong-term black carbon [BC] and PM2.5 levels, serum calcium homeostasis biomarkers (parathyroid hormon

132 ic bone disease, as a consequence of reduced serum calcium, hypoproteinuria, and hypoglycemia leading

133 performed genome-wide association study for serum calcium in >300 000 European-ancestry participants

134 66.5% patients had serum calcium in target range (8.4-10.2 mg/dl), 41.5% pa

135 diverged thereafter with significantly lower serum calcium in the 19-norD(2)-treated rats by 5 d.

136 nce-daily treatment with PTH 1-34 maintained serum calcium in the normal range with decreased urine c

137 In contrast, serum calcium in the VD(3) group was significantly eleva

138 substitute for vitamin D in the elevation of serum calcium in vitamin D-deficient rats.

139 Serum calcium indexes were taken throughout the study, a

140 Outcomes measures included serum calcium, intact parathyroid hormone (iPTH), and th

141 Here, we investigate whether serum calcium is a causal risk factor for changes in ECG

142 Maintenance of the normal serum calcium is a result of tightly regulated ion trans

143 ntrol of serum phosphorus without increasing serum calcium is an important goal for patients with ESR

144 f PTH secretion in response to variations in serum calcium is mediated by G-protein coupled, calcium-

145 thyroidism of renal failure, where a rise in serum calcium is undesirable.

146 weeks after treatment, PTX resulted in lower serum calcium level (9.28 mg/dL) compared with CIN (10.2

147 vs 23 [79.3%] female; P = .78), preoperative serum calcium level (mean [SD], 11.1 [0.9] vs 10.8 [0.8]

148 Associations between serum calcium level and baseline hematoma volume and bet

149 vel and baseline hematoma volume and between serum calcium level and ICH expansion were investigated

150 PTX led to a greater reduction in serum calcium level and lower chance of persistent hyper

151 Despite the normalization of serum calcium level and pulses of steroid treatment for

152 identified initial AVA, current smoking, and serum calcium level as the independent predictors of amo

153 Hypocalcemia is a derangement in serum calcium level due to a vast spectrum of disorders,

154 ecreased by 52% from 92 to 44 pg/mL, and the serum calcium level increased from 7.8 to 8.5 mg/dL.

155 Objective: To investigate whether a low serum calcium level is associated with an increase in th

156 15 mg/dL (normal level, <20 mg/dL), a total serum calcium level of 2.46 mmol/L (reference range, 2.1

157 admission, and hypocalcemia was defined as a serum calcium level of less than 8.4 mg/dL.

158 In this subgroup, a higher serum calcium level was associated with reduced risk of

159 A decreased serum calcium level was the only risk factor found to di

160 The serum calcium level was very low (3 mg/dl) due to damage

161 idectomy may be considered depending on age, serum calcium level, and kidney or skeletal involvement.

162 Serum calcium level, parathyroid hormone (PTH) level, an

163 valuating tumor growth, CD44 expression, and serum calcium level.

164 ,285 cases, 95,425 controls) and circulating serum calcium levels (39,400 subjects).

165 p and 10 in the placebo group), and elevated serum calcium levels (6 in the vitamin D3 + calcium grou

166 m a genome-wide association meta-analysis of serum calcium levels (N = up to 61079 individuals) and f

167 This lead SNP was associated with higher serum calcium levels [0.06 mg/dl (0.015 mmol/l) per copy

168 Serum calcium levels and change in serum creatinine leve

169 CaR is necessary for the fine regulation of serum calcium levels and renal calcium excretion indepen

170 between genetic variants related to elevated serum calcium levels and risk of coronary artery disease

171 -Fc > or =100 microg suppressed elevation of serum calcium levels and suppressed the bone turnover ma

172 Serum calcium levels and the Ca x P ion product increase

173 Corrected serum calcium levels and Voice Analog Score defined and

174 and 123504 noncases), the 6 SNPs related to serum calcium levels and without pleiotropic association

175 Serum calcium levels are tightly controlled by an integr

176 Serum calcium levels are tightly regulated.

177 hormone (iPTH) > or = 400 pg/ml, normalized serum calcium levels between 8.0 and 10.0 mg/dl, and cal

178 Finally, we found that elevation of serum calcium levels by 1 mg/dl resulting from our genet

179 with lifelong genetic exposure to increased serum calcium levels can be translated to a risk associa

180 The maximum serum calcium levels did not change (P = 0.15).

181 FBP lowered serum calcium levels during the first 24 h after the ins

182 Furthermore, raising serum calcium levels in Cyp27b1-depleted mice directly i

183 Serum calcium levels in the analogue group were not elev

184 The introduction of routine measurement of serum calcium levels led to a sharp increase in the inci

185 In patients older than 50 years with serum calcium levels less than 1 mg above the upper norm

186 The early rise in serum calcium levels observed with treatment may have co

187 imaging-guided MIP combined with uncorrected serum calcium levels of 2.55 mmol/l or less 1 month afte

188 These analyses support a causal effect of serum calcium levels on ventricular repolarization, in a

189 ectrochemical sensor that can measure bovine serum calcium levels on-site, providing an opportunity f

190 We found that the rate of change in serum calcium levels varied as a function of transmural

191 A genetic predisposition to higher serum calcium levels was associated with increased risk

192 crease (about 1 SD) in genetically predicted serum calcium levels were 1.25 (95% CI, 1.08-1.45; P = .

193 ization (MR) design to determine if elevated serum calcium levels were associated with risk of migrai

194 Serum calcium levels were increased only with vitamin D3

195 Serum calcium levels were measured with inductively coup

196 Postoperative mean serum calcium levels were similar (8.78 mg/dL, NIH group

197 aused a transient artifact in measurement of serum calcium levels with an OCP assay but not with an a

198 litate optimal bone mineralization, preserve serum calcium levels within a narrow range, and support

199 pt mean ages, 55 versus 65, and preoperative serum calcium levels, 11.5 mg/dL versus 11.0 mg/dL (NIH

200 ion of gadoversetamide caused no decrease in serum calcium levels, as measured with inductively coupl

201 orphological response and a normalization of serum calcium levels, confirming the hypothesis of a cal

202 Serum calcium levels, however, were unaffected by nephre

203 D3 and parathyroid hormone levels, decreased serum calcium levels, hyperplasia of the parathyroid, an

204 s that calcium supplementation, which raises serum calcium levels, may increase the risk of cardiovas

205 rathyroidism is typically diagnosed with low serum calcium levels, often requiring patients to remain

206 Feature importance analyses highlighted serum calcium levels, temperature, age, lymphocyte count

207 their ability to act in vivo without raising serum calcium levels, they may be of considerable intere

208 parathyroid hormone levels and low-to-normal serum calcium levels, were younger, and were receiving a

209 ould be achieved without adversely affecting serum calcium levels.

210 mon genetic variations associated with total serum calcium levels.

211 type, were able to reproduce, and had normal serum calcium levels.

212 hanisms that maintain skeletal integrity and serum calcium levels.

213 l in the blood did not affect measurement of serum calcium levels.

214 wk of treatment, concomitant with a rise in serum calcium levels.

215 tions, both in the context of high or normal serum calcium levels.

216 ed to explain about 0.8% of the variation in serum calcium levels.

217 arathyroid hormone in response to changes in serum calcium levels.

218 ased on genetic variants related to elevated serum calcium levels.

219 e was 100%, as evidenced by normalization of serum calcium levels.

220 tment for potential confounders, uncorrected serum calcium <8.5 and >/=10.2 mg/dl were associated wit

221 of renin-angiotensin system inhibitors, low serum calcium (< 8.4 mg/dL), and high uric acid levels (

222 th the experimental evidence, suggest higher serum calcium may increase the risk of CAD.

223 Changes in serum calcium measurements following gadodiamide adminis

224 lowing 42 gadodiamide-enhanced examinations, serum calcium measurements spuriously decreased by more

225 were in active follow-up, including regular serum calcium measurements.

226 The combined model of NEWS and serum calcium (NEWS-Calcium) is hypothesized to enhance

227 hypercalcemic that became undetectable when serum calcium normalized.

228 erformed to approximate the causal effect of serum calcium on QT, JT, and QRS intervals using an inve

229 At the multivariate analysis, serum calcium, OPG, and estimated glomerular filtration

230 of DBP(-/-) animals failed to show either a serum calcium or 25(OH)D response despite having normal

231 patient age, renal function, or preoperative serum calcium or parathyroid hormone levels.

232 with any sex hormone or reproductive factor, serum calcium, or circulating 25-hydroxyvitamin D concen

233 che diagnoses, and that genetically elevated serum calcium over lifetime appears to increase risk for

234 a decrease of heartrate by 9.9 bpm/mM total serum calcium (p < 0.001) with intact autonomic control

235 in D intakes were positively associated with serum calcium (P < 0.005) and calcidiol (P < 0.01) conce

236 ntributed significantly to the prediction of serum calcium (P < 0.009) and calcidiol (P < 0.0001), th

237 D concentration was the primary outcome, and serum calcium, parathyroid hormone (PTH), 1,25-dihydroxy

238 Patients were followed up for serum calcium, parathyroid hormone levels, and symptomat

239 In contrast, serum calcium, parathyroid hormone, and 25-hydroxyvitami

240 sted to achieve consistent albumin-corrected serum calcium, patients were randomly assigned (2:1) via

241 pletely rescued the hypercalciuric and lower serum calcium phenotype in Ksp-cre;Pth1r(fl/fl) mice, em

242 Laboratory evaluations included serum calcium, phosphate, alkaline phosphatase, 25-hydro

243 Serum calcium, phosphate, and vitamin D levels were norm

244 Runx2 deletion did not affect serum calcium, phosphate, fibroblast growth factor-23, o

245 There were no significant changes in serum calcium, phosphate, or intact parathyroid hormone

246 Serum calcium, phosphate, urea nitrogen, and creatinine

247 us; higher body mass index; higher levels of serum calcium, phosphorous, and parathyroid hormone; and

248 In sensitivity analyses, the addition of serum calcium, phosphorus, 25-hydroxyvitamin D, intact p

249 gender, age, diabetic status, and levels of serum calcium, phosphorus, alkaline phosphatase, and alu

250 Serum calcium, phosphorus, alkaline phosphatase, and par

251 ion to the more widely recognized changes in serum calcium, phosphorus, and 1alpha,25-dihydroxyvitami

252 Cinacalcet also significantly reduced serum calcium, phosphorus, and Ca x P levels compared wi

253 l excretion of calcium; and no difference in serum calcium, phosphorus, and PTH levels.

254 rly, the hematocrit, white blood cell count, serum calcium, phosphorus, cholesterol, triglycerides, t

255 No change occurred in serum calcium, phosphorus, intact parathyroid hormone, o

256 Baseline serum calcium, phosphorus, magnesium, and PTH levels wer

257 Serum calcium, phosphorus, osteocalcin, and alkaline pho

258 The serum calcium-phosphorus product declined by 15 percent

259 genome-wide studies of serum calcium (CASR), serum calcium-related risk of CHD (CASR), coronary arter

260 FHH3 probands had significantly greater serum calcium (sCa) and magnesium (sMg) concentrations w

261 cluded age, sex, estimated GFR, albuminuria, serum calcium, serum phosphate, serum bicarbonate, and s

262 Changes in plasma PTH, serum calcium, serum phosphorus, and calcium x phosphoru

263 Total serum calcium showed a null association in EPIC.

264 mmortalizes human keratinocytes and inhibits serum/calcium-stimulated differentiation.

265 ee made 1 strong recommendation for baseline serum calcium testing, 13 conditional recommendations, a

266 in patients with an asymptomatic increase in serum calcium to >12.0 mg/dl persisting for >1 year afte

267 ys showed a significant (P <.05) decrease in serum calcium values after administration of gadoverseta

268 s, as well as intact parathyroid hormone and serum calcium values obtained 1 d after surgery and on f

269 The decrease in serum calcium values peaked immediately after injection,

270 lues peaked immediately after injection, and serum calcium values quickly returned to baseline.

271 adoteridol produced no significant change in serum calcium values, regardless of analytic method.

272 Serum-calcium values were similar (2.1 +/- 0.3 vs 2.1 +/

273 a were compiled to determine how GBP affects serum calcium, vitamin D, and PTH.

274 A decrease of 0.1 mmol/L serum calcium was associated with longer QT (3.01 ms [95

275 Serum calcium was corrected for serum albumin.

276 Serum calcium was elevated and endogenous PTH was suppre

277 ent with 3 previous cohort studies, elevated serum calcium was found to be associated with a greater

278 and U/HP mice versus sham controls, whereas serum calcium was increased in the U/HP group, and no di

279 Serum calcium was measured at baseline and corrected for

280 Serum calcium was measured in an 8% subsample of partici

281 quintiles, in both cohorts, higher levels of serum calcium were associated with reduced CRC risk (EPI

282 19-norD(2) or 1,25(OH)(2)D(3), increases in serum calcium were identical 24 h after the first inject

283 ar between groups except that hemoglobin and serum calcium were lower and serum phosphorus was higher

284 nical performance measures including monthly serum calcium were obtained through linkage to the Conso

285 ignificant (P <.05) decrease in the value of serum calcium when analyzed with the OCP technique but n

286 ase in dietary calcium for 10 days increased serum calcium, with an associated increase in FGF23, dec