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1 nation and Elaboration (E&E) document, which serves (1) to explain the rationale behind each item in
2 Explanation and Elaboration document, which serves (1) to explain the rationale behind each item in
8 natal mitochondrial biogenesis and function, serve a role in the broader cardiac maturation program.
9 cancer cohort, we signifies that MOVICS can serve a wide range of users and assist cancer therapy by
10 ty and ROS accumulation, suggesting that NNT serves a specific role in mitigating the oxidation of th
13 with anthrose, indicating that anthrose may serve an antiphagocytic function on the spore surface.
14 the SWI/SNF chromatin-remodeling complexes, serves an indispensable role in cold-induced thermogenes
15 regions and relay it to other brain regions, serving an essential role in sensory perception and moto
16 -oxidation and the electron transport system serve as a barometer of substrate flux relative to deman
17 of the dynamics of the pasture ecosystem and serve as a basis for managing livestock in a more effici
18 dge of bacterial ribosome structures and may serve as a basis for the development of novel antibiotic
19 eover, expression of PAX8 in cancer can also serve as a biomarker for diagnostic and prognostic purpo
20 T-type calcium channel (TTCC) expression may serve as a biomarker for melanoma progression and progno
22 ed from the nucleus or mitochondria can also serve as a cGAS ligand to activate this pathway and trig
23 emission properties, the mixture of MURs can serve as a cocktail sensor for multiplex optical urinaly
25 ARRDC3 protein directly interacts with IR to serve as a feedback regulator of insulin action in contr
28 haematopoietic dysfunction, the BM chip may serve as a human-specific alternative to animal testing
29 cantly affects the optical response, and can serve as a key tuning parameter in tailoring the polarit
32 al RNA-binding protein, and its potential to serve as a matchmaking RNA chaperone, significant gaps r
33 gineered on the basis of HC84.26.5D may also serve as a means of doubling the effective size of conve
34 teria and demonstrates that this process can serve as a mechanism for intracellular organization in p
35 insights into COVID-19 pathogenesis and can serve as a model for understanding human respiratory dis
36 e-alkoxide (POV-alkoxide) cluster, which can serve as a molecular model for halogen-doped vanadium ox
38 ain a degree of nicotine dependence and also serve as a noncombustible substitute for cigarettes.
42 ch means the bioreactor has the potential to serve as a platform for investigating the behavior of 3D
43 d radiometal chelate (FERM) was developed to serve as a platform for multimodal imaging probe develop
44 n details regarding mechanostability and can serve as a platform for novel mutagenesis studies as wel
45 class of intrinsically porous nanocarbons to serve as a platform for studying the transition from ana
46 in synaptic transmission and plasticity may serve as a possible biological mediator of this associat
49 evidence that glutamine supplementation can serve as a potential dietary intervention to block melan
50 PRSS2 in human prostate cancer cells and may serve as a potential factor to suppress TMPRSS2-mediated
51 cascade in GBM invasion and suggest GBP2 may serve as a potential therapeutic target for inhibiting G
52 icly available resource has the potential to serve as a powerful medium for probing the etiology of d
53 level housing-based SES index (HOUSES) would serve as a predictive tool for graft failure in patients
54 t the H/D primary kinetic isotope effect can serve as a probe for these mechanisms, as confirmed in v
55 ity to 6-thio-dG and therefore SLC43A3 could serve as a promising biomarker for 6-thio-dG sensitivity
57 In conclusion, CD163-expressing macrophages serve as a protective mechanism to prevent the deleterio
59 that mid-infrared spectroscopic imaging may serve as a quantitative diagnostic tool for quantitative
60 rom patients hospitalized with pneumonia may serve as a reliable and accessible sample to evaluate bi
62 of this work was to evaluate whether CgA can serve as a response predictor for (177)Lu-prostate-speci
63 ted by the sensory cells of the inner ear to serve as a sound source microphone for fully implantable
65 panded under a warmer climate, this work may serve as a starting point for investigating socioeconomi
66 vidence also suggests that ATMs of lean mice serve as a substrate buffer or reservoir to modulate lip
68 r and more common postdonation outcome could serve as a surrogate to individualize counseling and man
71 s suggest that constrained poetic structures serve as a temporal map for listeners to group speech co
74 nd anacardic acid as a candidate molecule to serve as a therapeutic agent to promote remyelination.
75 athway to inhibit eosinophil recruitment may serve as a therapeutic strategy for management of eosino
76 drug-like properties, and targeting SHP2 may serve as a therapeutic strategy to overcome tumor resist
77 ly, we generate Pourbaix phase diagrams that serve as a thermodynamic atlas to indicate which compoun
78 e findings from this pre-clinical model will serve as a tool for screening therapeutic strategies to
79 in veterinary burn victims are warranted and serve as a translational research opportunity for uncove
80 These results support that cancer trap may serve as a unique device to sequester circulating PCa ce
81 ed flow or occlusion) in retinal vessels may serve as a useful diagnostic indicator of disease progre
83 e through historical texts and artifacts can serve as a valuable, and almost completely unutilized, s
84 on and metal-containing cofactor, which will serve as a valuable, integrative data source to foster m
85 enging visuomotor behaviors and may possibly serve as a window into the subject's dynamically evolvin
87 pose the dopamine stabilizer (-)-OSU6162 may serve as an adjunct pharmacological treatment to prevent
90 zed graphene hybrid composite is reported to serve as an effective photoactive component with enhance
91 r early or late in the disease process could serve as an effective protein replacement therapy for LA
92 Several studies have shown laminin-111 can serve as an effective protein-replacement therapy for LA
93 th validation in larger cohorts, SHIFT could serve as an efficient preliminary, auxiliary, or substit
95 ion, nomenclature and data aggregation could serve as an example for cell type atlases in other parts
102 net based on nonanuclear RE(9)-clusters, to serve as bicapped trigonal prismatic building units.
103 and uniquely selective D3R agonist that may serve as both a research tool and a therapeutic lead for
106 dicates that these epigenetic biomarkers may serve as complementary measures for the diagnosis and pr
107 similar NMDAR modulators, could potentially serve as complementary treatment for anti-NMDAR encephal
108 patterns (or combined with other compounds) serve as conductive traces and sensing electrodes, and o
109 now and other cold-water sources continue to serve as critical climate refugia for mountain biodivers
110 odifications of proteins at DNA damage sites serve as DNA damage codes to recruit specific DNA repair
115 be to stage processes during bioproduction, serve as environmental sentinels or guide living therape
116 and other mood comorbidities, these findings serve as evidence of altered neurochemistry in BD youth
117 on of rate ratios or to allow each person to serve as his/her own control (as we see with case-cohort
118 f not all, prokaryotic LRS membrane proteins serve as inhibitors of their cognate transcription regul
119 surgical science over the decades and should serve as inspiration for all surgeons and surgical inves
120 mponents of plasma membrane because they may serve as interaction, condensation, and nucleation point
122 actors CAMTA1, CAMTA2, and CAMTA3 (CAMTA123) serve as master regulators of salicylic acid (SA)-mediat
124 al support for plasmonic nanocrystals, which serve as nanoheaters, and reducing the diffusion rate of
126 e to latent HIV infection in the gut and may serve as new targets for therapies aimed at curing HIV.
128 , both chromatin and RNA modifications could serve as novel targets for the development of antivirals
129 ial cells of the C. elegans amphid apparatus serve as odorant receptor cells and regulate neuronal ou
130 t role in microbiome communities, they could serve as opportunistic pathogens in immunocompromised ho
133 ed to identify orofacial conditions that can serve as potential risk markers for cancers by performin
135 this PFC-BNST dynorphin-related circuit may serve as potential targets for potential therapeutic med
136 tion, ILC frequencies in early pregnancy may serve as predictive biomarkers for women who are at risk
137 proteins and mRNA-encoded sequence elements serve as primary determinants of gene regulation in thes
138 uded that the mixed oat-buckwheat breads may serve as products with a medium GI, as a source of TPC,
139 s them improved bioavailability, making them serve as reagents for bacterial imaging and killing.
140 studies, in humans and animal models, which serve as reassuring de facto positive controls for our w
141 have many physiological functions; they can serve as receptors for bacteriophages, and provide a sub
142 ts and eosinophil cationic proteins that may serve as risk factors for human coronary heart diseases.
143 ontrast agents and the potential of IONPs to serve as safe and improved alternative to gadolinium-bas
144 hored to the outer surface of the phagophore serve as scaffolds for binding of other core autophagy p
145 identified in several foldamer families can serve as scaffolds for the predictable spatial arrangeme
146 xylipins that impair grazer reproduction and serve as signaling molecules to nearby undamaged diatoms
148 ts and space-for-time substitution sites can serve as sources of knowledge and can be used to test mo
149 utations were previously identified that may serve as substrates for RMCE reactions for future potent
150 erated in the PCET event are hypothesized to serve as the basis for asymmetric induction in a subsequ
153 tanding of bradykinesia pathophysiology will serve as the new starting point for clinical and experim
155 e thin film, SrTiO(3), that is well known to serve as the substrate for epitaxial growth of other fun
156 ucturally homologous Mtf1 and TFB2M proteins serve as transcription initiation factors of mitochondri
158 re of olmesartan-bound human AT1R (PDB:4ZUD) served as a template to create an inactive apo-AT1R via
161 d if they focused solely on contrast agents, served as commentaries/overviews on NIRAF or were not wr
163 of individual organs and entire animals have served as invaluable entry points for ensuing dissection
164 of patients with non-small cell lung cancer served as model for three 3-dimensionally printed insert
166 ules (UBXN4, MFSD12, and ACTR6) from RNA-seq served as potential prognostic markers for lung cancer,
167 potential consequence of both regions having served as refugia during glacial advances in the late Qu
168 hnicity, insurance, and documentation status served as risk factors for disparities in traumatic brai
169 Microwave atomic clocks have traditionally served as the 'gold standard' for precision measurements
173 d cell cycle progression in U. maydis, which serves as a "toggle switch" to control the fungal decisi
174 steric nature of the sulfonyl moiety, which serves as a base-labile protecting group and confers cry
175 Overall, AM secretion of SOCS3 within EVs serves as a brake on airway EC responses during allergic
177 evidence base, with the hope that this paper serves as a catalyst for a renewed research agenda into
179 y established that the Med1 Mediator subunit serves as a cofactor of GATA TFs in Drosophila, as shown
180 stable metalloradical, (P(3) (B) )Co(H(2) ), serves as a competent precursor for hydrogen atom transf
182 set of symmetries of barcode covariance that serves as a consistency check for the validity of the me
183 e findings, we propose a model in which LuxR serves as a counter-silencer at H-NS-repressed quorum se
184 cinetobacter pathogenesis and that histidine serves as a crucial nitrogen source during infection.
185 1 (PCBP1) is a multifunctional protein that serves as a cytosolic iron chaperone, binding and transf
186 lar succinate, a TCA cycle intermediate that serves as a direct electron donor to mitochondrial compl
187 gens are enveloped by an outer membrane that serves as a double-edged sword: On the one hand, it prov
188 re-emerging and endemic infectious diseases serves as a frequent reminder of the need to understand
189 dization in a fixed direction, while the DNA serves as a functional group equivalent, connecting comp
190 e in human evolution, suggest that admixture serves as a fundamental mechanism that drives rapid adap
192 presents a new computational framework that serves as a high throughput method to evaluate risk of g
193 post-transcriptional regulation of tankyrase serves as a ligand-independent developmental mechanism f
194 and the virion envelope glycoprotein B (gB) serves as a major target of neutralizing antibodies.
195 (HMPV) as a model, we demonstrate that m(6)A serves as a molecular marker for innate immune discrimin
197 otection to the cell, and the outer membrane serves as a permeability barrier against noxious compoun
199 s a Ca(2+) -activated Cl(-) conductance that serves as a primary pacemaker conductance in ICs of the
202 s unique insight into ASFV transcription and serves as a resource to aid future functional analyses o
203 the sound spectrum is integrated quickly and serves as a salient discrimination cue while high-order
206 gations indicate that trimethyl orthoformate serves as a source of methyl radical via beta-scission f
207 these "condensation reactions", the polymer serves as a steric guide to limit DNA hybridization in a
208 novirus to yield a new AAV variant that then serves as a template for evolving the next surface loop.
209 , constitutive CCL5 expression by CD8(+)T(M) serves as a unique functional imprint of prior antigenic
215 a result, the prepared solid/colored formula serves as an ideal formulation for such instable drug in
218 ell cycle, the microtubule (MT) cytoskeleton serves as both a supportive scaffold for organelles and
219 ture is selected as the parent oxide, and Ir serves as the active metal species that produces the ex-
221 component of eukaryotic membranes that also serves as the common precursor for polyphosphoinositide
222 y sequestration of neutrophils (PMNs), which serves as the first event in the acute respiratory distr
223 across isostructural UiO-66 frameworks, and serves as the foundation for future plutonium MOF chemis
225 prevailing hypothesis that membrane fluidity serves as the measured variable for regulating lipid sat
228 riction factor that protects against ZIKV by serving as a decoy receptor, and plays a protective role
229 e American Heart Association is committed to serving as a global champion and leader in RHD care and
230 g was driven by dsRNA from live A. fumigatus serving as a key vitality-sensing pattern recognition re
232 ar protection against oxidative stress while serving as a reactive oxygen species (ROS)-activated per
235 CoV-2 RNA-dependent RNA polymerases (RdRps), serving as an immediate polymerase reaction terminator,
239 per enzymes promote NO release from RSNOs by serving as Lewis acids for intramolecular electron-trans
240 ter-in-oil-in-water double emulsion droplets serving as single-cell enzymatic micro-reactors and a co
241 em resistance in the Philippines, while also serving as the genetic background to contextualize ongoi
242 turn, stimulated the T-cell infiltration by serving as the ligand and chemoattractant for CXCR3(+) T
244 nd perhaps compensatory neural dynamics, sub-serving auditory working memory, remains largely unexplo
245 Men were selected on a first-come first-served basis (n = 130; M age = 45.8, SD = 8; M BMI = 34.
246 some patients and can therefore potentially serve both as a dual diagnostic and therapeutic tool.
248 ) were more likely in the Southwest (61.1%), served by groundwater (94.7%), serving smaller populatio
249 in different locations throughout the body, serve distinct roles, and are activated by a variety of
250 tage-specific manner during B lymphopoiesis, serving either to facilitate or to impose a barrier to V
252 .18 mm), and was associated with larger self-served food portions (5.03 kcal; 0.47, 9.60 kcal), faste
253 ide, suggesting that although the PEP domain serves for recognition and orientation, interaction with
254 ate cis-regulatory elements (cCREs) that may serve functional roles in regulating gene expression(1).
257 ical illness mortality within a non-minority-serving hospital, but no change within minority-serving
258 ving hospital, but no change within minority-serving hospitals (hazard ratio, 0.99; 95% CI, 0.97-1.01
259 ule-binding motor protein superfamily, which serves important roles in cell division and intraorganel
260 ster from the SUFBC(2)D scaffold complex and serves in the maturation of specific [4Fe-4S] client pro
261 ting flow patterns which trap particles, may serve many of the properties associated with compartment
262 w-fat dairy other than yogurt relative to <1 serving/mo and 1.06 (95% CI: 0.91, 1.25, P trend = 0.36)
264 As with morphological weapons, venom can serve multiple purposes, including to facilitate feeding
265 Patients cared for at the most disadvantaged-serving practices (group 5) were more likely to be admit
267 west (61.1%), served by groundwater (94.7%), serving smaller populations (mean 1,102 persons), and se
268 cids) comprising nonpolar and polar portions serving the universal and robust adhesive properties.
270 dicating that mainly interocular comparisons serve to compute an object's movement at close range.
273 in association with theta activity and could serve to enhance sensory-motor processing and memory con
274 he static structure of the enzyme but rather serve to fine-tune the activity and efficiency of MCR.
276 rker, short telomere length (TL), that might serve to identify patients more likely to die from the S
277 cence, and it is believed that these changes serve to improve the functions of circuits that underlie
279 istant spacing of ovule primordia, which may serve to minimize competition between seeds or facilitat
282 2 BCS patients and the 7 mastectomy patients served to build a set of images for reader training.
283 ial resistance in Salmonella Typhi that have served to increase interest in typhoid elimination.
284 WPEDs also contain a heating layer that serves to both stimulate sweating and prevent saturation
285 ion of two 16S rRNA residues, and ultimately serves to coordinate subunit joining through the release
287 ividuals.SIGNIFICANCE STATEMENT This project serves to determine whether dopamine neurons encode diff
288 the most frequent events in human cancer and serves to disconnect the control of cell growth, surviva
289 demonstrate that this reciprocal regulation serves to fine tune the splicing patterns of many downst
290 olding, secretion, and energy production and serves to maintain protein homeostasis in various cellul
292 TPN overview of achievements in nanomedicine serves to reinforce our drive towards further expanding
293 in aberrant adenosinergic signalling, which serves to sustain inflammasome activation and worsen fib
294 n that can bind specific DNA motifs, thereby serving to either activate or repress transcription of s
295 velop a multinucleate nurse cell (syncytium) serving to nourish the nematode over its 30-day life cyc
296 e studies illustrate that although HIV-1 RNA serves two functions, as a translation template and as a