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1 erposition graft in the abdominal aorta of a severe combined immunodeficient Beige mouse model suppor
4 tacrolimus, Bonferroni's P<0.001) and in the severe combined immunodeficient-beige mice (117+/-18 in
7 fused W6/32 Fab'2 antibody to human HLA into severe combined immunodeficient/beige mice that had been
8 To address this we used nonobese diabetic-severe combined immunodeficient-beta(2) microglobulin kn
9 ion of ospA mRNA was found in tissues of C3H-severe combined immunodeficient (C3H-scid) mice, but not
10 Human fetal lung tissue was implanted into severe combined immunodeficient (CB17-scid) mice and ino
13 s to restore euglycemia in nonobese diabetic/severe combined immunodeficient diabetic recipients was
14 the recurrence of autoimmune diabetes in NOD/severe combined immunodeficient disease (SCID) islet iso
15 al vein of either C57BL/6 (DNA-PKcs(+/+)) or severe combined immunodeficient (DNA-PKcs(-/-)) mice.
19 f immunocompetent limited flora (I-LF) mice, severe combined immunodeficient limited flora (SCID-LF)
20 antation of these cells in nonobese diabetic-severe combined immunodeficient mice (a) generated xenog
21 fts in three genetically isolated strains of severe combined immunodeficient mice (C.B-17, C57BL/6J,
22 uction of the human HGF ligand in transgenic severe combined immunodeficient mice (hHGF(tg)-SCID mice
25 mum tolerated dose of 2L-Rap-hLL1-gamma4P in severe combined immunodeficient mice (SCID) or BALB/c mi
26 ntitumor effects were markedly diminished in severe combined immunodeficient mice and (b) CD8+ T cell
29 nted tumors when transplanted into syngeneic severe combined immunodeficient mice and normal mice.
30 MDMs were injected into the basal ganglia of severe combined immunodeficient mice and then Li was adm
31 e studied the effects of THMAM-MD in vivo in severe combined immunodeficient mice bearing HT-29 colon
34 ncer and significantly prolonged survival of severe combined immunodeficient mice bearing LAPC-4 xeno
35 activity of 8H9(scFv)-PE38 was evaluated in severe combined immunodeficient mice bearing MCF-7 breas
38 PET/CT small-animal imaging was performed in severe combined immunodeficient mice bearing solid and d
41 e drug combination decreased tumor volume in severe combined immunodeficient mice by approximately 60
42 growth and the gain in mean tumor volume in severe combined immunodeficient mice compared with vehic
43 nd engraft immunodeficient nonobese diabetes/severe combined immunodeficient mice during both primary
44 cific neutralizing anti-CXCL12 antibodies to severe combined immunodeficient mice expressing human no
45 on of late-passage H-Ras-expressing cells in severe combined immunodeficient mice formed carcinomas w
46 eplication in nontumor tissues and protected severe combined immunodeficient mice from developing let
47 was used in vivo to treat nonobese diabetic/severe combined immunodeficient mice given injections of
49 he marrow space of the bone implanted in the severe combined immunodeficient mice implanted with feta
50 0530 profoundly inhibits tumor metastasis in severe combined immunodeficient mice implanted with GRP-
54 CDV) and octadecyloxyethyl-CVD (ODE-CDV)--in severe combined immunodeficient mice in which either hum
55 5(+) T cells to infected macrophage-depleted severe combined immunodeficient mice induced CNS demyeli
56 ionship between phospho-AKT and FAS in vivo, severe combined immunodeficient mice injected intraperit
57 meliorated adoptively transferred ileitis in severe combined immunodeficient mice injected with CD4 +
59 dies, BMSCs and ECs were cotransplanted into severe combined immunodeficient mice on biodegradable po
60 t study, we induced EAE in T-cell-deficient, severe combined immunodeficient mice or in immunocompete
62 th a targeted deletion of the T-bet gene and severe combined immunodeficient mice receiving CD4+ cell
63 er growth was evaluated in hu-PBL-SCID mice (severe combined immunodeficient mice reconstituted with
65 uman ovarian tumor cells into the ovaries of severe combined immunodeficient mice resulted in periton
66 racranial implantation of human gliomas into severe combined immunodeficient mice showed a marked red
67 The standard adoptive transfer study in NOD-severe combined immunodeficient mice showed that periphe
69 following immunization of nonobese diabetic-severe combined immunodeficient mice that were repopulat
72 cells harvested from carcinoma formation in severe combined immunodeficient mice were designated caM
78 tin-expressing tumors grown as xenografts in severe combined immunodeficient mice were responsive to
81 ive, Fc-dependent, passive immunity, even in severe combined immunodeficient mice with an established
82 inst subcutaneous B-cell tumor xenografts in severe combined immunodeficient mice with comparable or
83 HCV-infected urokinase plasminogen activator-severe combined immunodeficient mice with livers repopul
84 Furthermore, Kp-10 inhibits tumor growth in severe combined immunodeficient mice xenografted with hu
86 volume, rate of metastasis, and mortality of severe combined immunodeficient mice xenografted with PC
87 model originating from footpad injection in severe combined immunodeficient mice, 95% of the resulti
88 ondii in BALB/c mice, immunocompetent, or in severe combined immunodeficient mice, and after treatmen
89 ere injected directly into the peritoneum of severe combined immunodeficient mice, and in a syngeneic
90 neither resulted in weight loss nor death in severe combined immunodeficient mice, and pock lesions w
91 the growth of TPras transgenic melanomas in severe combined immunodeficient mice, blocked invasive b
92 model established by tail vein injection in severe combined immunodeficient mice, clonality of lung
94 sgene expression was substantially higher in severe combined immunodeficient mice, indicating that in
95 as far less efficacious in immunocompromised severe combined immunodeficient mice, indicating the req
97 ally injected into the basal ganglia of CB17 severe combined immunodeficient mice, received daily int
100 When injected into the mammary fat pads of severe combined immunodeficient mice, the tumors formed
102 Finally, using an angiogenesis assay in severe combined immunodeficient mice, we demonstrate tha
103 lls, bone marrow chimeras, and reconstituted severe combined immunodeficient mice, we identify the pr
104 ation of SKOV3ip1 cells in nonobese diabetic/severe combined immunodeficient mice, with increased pho
146 d not express uPAR formed palpable tumors in severe combined immunodeficient mice; however, metastase
147 asion assays, and/or injected into flanks of severe combined immunodeficient mice; xenograft tumor gr
148 owth of malignant mesothelioma xenografts in severe-combined immunodeficient mice and extended host s
152 line (EGI-1) after xenotransplantation into severe-combined-immunodeficient mice, (3) expression of
153 6Mre11(ATLD1/ATLD1) and C57BL/6(Prkdc/SCID) (severe combined immunodeficient) mice exposed to low-dos
154 ation in soft agar, tumor formation in SCID (severe combined immunodeficient) mice, and adhesion.
157 an peripheral blood leukocytes (hu PBL-SCID [Severe Combined Immunodeficient] mice) to test the hypot
159 prevent progression of established CaP in a severe combined immunodeficient mouse implanted with fet
160 f normal islets in a streptozotocin-diabetic severe combined immunodeficient mouse marginal islet mas
172 one B (dEpoB) in xenograft nonobese diabetic/severe combined immunodeficient mouse models with subcut
174 ound to inhibit pancreatic tumor growth in a severe combined immunodeficient mouse xenograft model.
175 c. human GD2-positive melanoma growth in the severe combined immunodeficient mouse xenograft model.
176 These investigations in a nonobese diabetic severe combined immunodeficient mouse-human neural cell
178 dicates that the NOD/SCID (nonobese diabetic/severe combined immunodeficient) mouse model can be a va
179 ta-glucuronidase-deficient nonobese diabetic/severe combined immunodeficient/mucopolysaccharidosis ty
180 geneic graft-versus-host disease (X-GVHD) in severe combined immunodeficient murine recipients of hum
181 bet knockout (KO) mutants, or congenic SCID (severe, combined immunodeficient) mutants were given liv
182 BD islets transplanted to non-obese diabetic-severe combined immunodeficient (NOD-SCID) mice efficien
187 population with use of the nonobese diabetic/severe combined immunodeficient (NOD/SCID) and NOD/SCID
188 ngraftment of AML cells in nonobese diabetic/severe combined immunodeficient (NOD/SCID) animals, and
190 ibialis anterior muscle of nonobese diabetic-severe combined immunodeficient (NOD/SCID) beta 2m(-/-)
191 higher tumor incidence in nonobese diabetic/severe combined immunodeficient (NOD/SCID) Ilgamma2(null
193 selected for passage into nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice and mini
194 imaging were done on male nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice bearing
195 is trial transplanted into nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice resulted
196 ns in the liver and gut of nonobese diabetic-severe combined immunodeficient (NOD/SCID) mice that und
197 gate the in vivo efficacy, nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice were xen
198 ultiple ALL cell lines and nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice xenograf
199 the retroorbital plexus of nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice, allowed
200 IM CD34(+) cells engrafted nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice, demonst
201 ncreased tumorigenicity in nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice, possibl
202 xenografts established in nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice, were di
207 Here we report that a new nonobese diabetic/severe combined immunodeficient (NOD/SCID) mouse line ha
208 er, when injected into the nonobese diabetic/severe combined immunodeficient (NOD/SCID) mouse prostat
209 We examined whether the nonobese diabetic/severe combined immunodeficient (NOD/scid) mouse, which
211 ll as stem cells using the nonobese diabetic/severe combined immunodeficient (NOD/SCID) xenograft mod
212 Stem cell engraftment into nonobese diabetic-severe combined immunodeficient (NOD/SCID)/beta2m-/- mic
213 (+) B-cell malignancies in nonobese diabetic/severe combined immunodeficient (NOD/SCID)/gamma(c)(null
214 regression was blocked in nonobese diabetic/severe combined immunodeficient (NOD/SCID-gamma) mice, w
215 e therefore developed an in vivo MM model in severe combined immunodeficient/nonobese diabetic mice i
216 rsus FasL(-/-) mouse liver CD8(+) T cells to severe combined immunodeficient or RAG1(-/-) recipient m
219 nfected donors expanded in reovirus-infected severe combined immunodeficient recipient mice and media
220 il also improved transduction in human SCID (severe combined immunodeficient) repopulating cell (SRC)
223 or its ability to protect wild-type (WT) and severe combined immunodeficient (SCID) C.B-17 mice again
224 uated envelope SU cloned sequences from five severe combined immunodeficient (SCID) foals infected wi
225 raacetic acid (DOTA)-RGD in 20 tumor-bearing severe combined immunodeficient (SCID) mice after a bolu
227 titumor effects of MEDI-575 in tumor-bearing severe combined immunodeficient (SCID) mice and in genet
228 xpressed in autoimmune target tissues of NOD/severe combined immunodeficient (scid) mice and of autoi
229 in the brain's extracellular space of C.B.17 severe combined immunodeficient (scid) mice and tumor ce
230 antibody significantly prolonged survival of severe combined immunodeficient (SCID) mice bearing CD70
231 f B-B4-DM1 in 3 human MM models in mice: (1) severe combined immunodeficient (SCID) mice bearing subc
232 e tissues (5-8), two studies have shown that severe combined immunodeficient (SCID) mice can be infec
234 iver homogenates after 24 serial passages in severe combined immunodeficient (SCID) mice caused sever
235 ted in urokinase plasminogen activator (uPA)/severe combined immunodeficient (SCID) mice engrafted wi
237 -dependent protein kinase (DNA-PK)-defective severe combined immunodeficient (SCID) mice have a great
238 be here a novel in vivo model of human WM in severe combined immunodeficient (SCID) mice implanted wi
240 vivo binding characteristics were studied in severe combined immunodeficient (SCID) mice inoculated w
241 splantation of purified HSCs into a panel of severe combined immunodeficient (SCID) mice leads to a r
242 and their splenocytes were transferred into severe combined immunodeficient (SCID) mice to induce IT
243 man dorsal root ganglion (DRG) xenografts in severe combined immunodeficient (SCID) mice to investiga
246 WT) mice were subjected to DNFB-induced CHS, severe combined immunodeficient (SCID) mice were injecte
247 nificantly extends survival of 697 xenograft severe combined immunodeficient (SCID) mice without disc
249 e was tested for its metastatic potential in severe combined immunodeficient (SCID) mice, by i.v. inj
250 When coinjected with human MM cells into severe combined immunodeficient (SCID) mice, green fluor
252 AML cells in vivo in nonobese diabetic (NOD)-severe combined immunodeficient (SCID) mice, suggesting
255 ith the cDNA for heparanase are implanted in severe combined immunodeficient (SCID) mice, the resulti
273 e studied hippocampal synaptic function in a severe combined immunodeficient (SCID) mouse model of HI
274 and tumor formation in an immunocompromized severe combined immunodeficient (SCID) mouse model of or
277 ntaneous metastasis assay was performed in a severe combined immunodeficient (SCID) mouse model.
278 med by human prostate cancer cell lines in a severe combined immunodeficient (SCID) mouse tibial inje
279 anti-proliferative effects in the human skin-severe combined immunodeficient (SCID) mouse transplant
280 e show that LRP-1 is abundantly expressed in severe combined immunodeficient (SCID) mouse xenografts
281 in psoriasis in an in vivo system using the severe combined immunodeficient (SCID) mouse-human skin
284 ive to adult bone marrow in allogeneic fetal severe combined immunodeficient (SCID) recipients compar
286 ymphocytes and within human thymic grafts in severe combined immunodeficient (SCID)-hu (Thy/Liv) mice
287 tivities of docetaxel both in culture and in severe combined immunodeficient (SCID)-human model of ex
288 we measure the activity of multipotent human severe combined immunodeficient (SCID)-repopulating cell
289 th pleiotrophin also substantially increased severe combined immunodeficient (SCID)-repopulating cell
290 wn in the epithelium-free mammary fat pad of severe combined immunodeficient (SCID)/Beige and nonobes
293 g plasmablasts can be enriched in vivo, in a severe combined immunodeficient (SCID)/beige mouse host.
294 (+) PMF CD34(+) cells into nonobese diabetic/severe combined immunodeficient (SCID)/IL-2Rgamma(null)
296 ed the growth of primary tumors in the human severe combined immunodeficient (SCID-hu) model of myelo
297 ibodies on an ATL model in nonobese diabetic/severe combined immunodeficient (SCID/NOD) wild-type mic
298 (PMNs) and in human intestinal xenografts in severe-combined immunodeficient (SCID-HU-INT) mice, a no
299 um antibodies to the systemic compartment of severe-combined-immunodeficient (SCID) mice temporarily