ライフサイエンスコーパス: sex steroid hormone

1 ing genetic predisposition and influences of sex steroid hormones.

2 losa cell proliferation and the synthesis of sex steroid hormones.

3 ke outcomes seen during life stages with low sex steroid hormones.

4 onse to changing photoperiod and circulating sex steroid hormones.

5 ence that likely results from the effects of sex steroid hormones.

6 ted with differences in circulating SHBG and sex steroid hormones.

7 as puberty approaches, and is independent of sex steroid hormones.

8 cancer cells, particularly that mediated by sex steroid hormones.

9 rogenase responsible for the inactivation of sex steroid hormones.

10 he rate-limiting step in the biosynthesis of sex-steroid hormones.

11 tes, are widely believed to lack male-biased sex steroid hormones(1).

12 The female sex steroid hormones 17beta-estradiol and progesterone m

13 The shifts in exposure to sex steroid hormones across a lifespan introduce additio

14 Sex steroid hormones act on hypothalamic kisspeptin neur

15 In order to better understand where sex steroid hormones act to regulate social behavior in

16 e data reveal mechanisms not only for female sex steroid hormone action but also in the regulation of

17 It is also a major site of sex steroid hormone action.

18 the physiology and pathophysiology of female sex steroid hormone actions in target organs.

19 We discuss the important role of sex steroid hormones and of neurotrophins in creating a

20 suggest a heritable component to circulating sex steroid hormones and sex hormone-binding globulin (S

21 Seven sex steroid hormones and SHBG were quantitated using gas

22 Seven sex steroid hormones and SHBG were quantitated using gas

23 sequent nuclear translocation in response to sex steroid hormones and stress stimuli.

24 ted with an increase in urinary excretion of sex steroid hormones and their metabolites in humans.

25 These results underscore the role of sex steroid hormones and their receptors in diseases tha

26 nes on the X chromosome, genes influenced by sex steroid hormone, and genes sex-differentially regula

27 use, it is becoming increasingly clear that sex steroid hormones, and in particular the principle fe

28 tions in endogenous postmenopausal levels of sex steroid hormones are not substantially related to th

29 sheep but not in monkeys or humans, although sex steroid hormones are still secreted.

30 Several endocrine factors, including sex-steroid hormones are known to influence adiponectin

31 e ERalpha in the human eye suggests that the sex steroid hormone axis may play a role in the pathogen

32 ductive function nonetheless, with levels of sex steroid hormones being highest during the spring and

33 We also detected differences in several sex steroid hormones between male and female subjects, w

34 Vocal plasticity is linked to the actions of sex steroid hormones, but the precise mechanisms are unc

35 in male 3xTg-AD mice depleted of endogenous sex steroid hormones by gonadectomy (GDX).

36 All sex steroid hormones can interact with receptors for dru

37 receptor- and progesterone receptor-mRNA in sex steroid hormone-concentrating brain areas of the par

38 t correlations between urinary BPA and serum sex steroid hormone concentrations in adults.

39 e assessed pubertal staging, measured plasma sex steroid hormone concentrations, and analysed semen q

40 Sex-steroid hormone concentrations were assayed by using

41 Sex steroid hormones contribute significantly to sex-bas

42 act symptoms (LUTS), and it is not clear how sex steroid hormones contribute to the rates of change i

43 ine epinephrine output (but not cortisol and sex steroid hormones) correlated inversely with proinfla

44 The phenotype depends on sex-steroid hormones: dihydrotestosterone treatment of g

45 oculture system was used to demonstrate that sex steroid hormones direct development of a sexually di

46 ally relevant circuit.SIGNIFICANCE STATEMENT Sex steroid hormones drive changes in brain circuits in

47 may be mediated by organizational actions of sex steroid hormones during development.

48 ns and songbirds is linked to the actions of sex steroid hormones during ontogeny but also in adultho

49 evaluated how the organizational effects of sex steroid hormones during postnatal development may af

50 brain regions develop under the influence of sex steroid hormones during the perinatal period, but ho

51 cent studies have shown that progesterone, a sex steroid hormone, enhances the sexual transmission of

52 The sex-steroid hormone estradiol (E2) enhances the psychoac

53 The female sex steroid hormones, estrogens and progesterone, are pr

54 Sex steroid hormones exert a profound influence on the s

55 Sex steroid hormones exert opposite effects on lung matu

56 ing and estradiol in the mechanisms by which sex-steroid hormone fluctuations provoke depressive symp

57 Sex steroid hormones have been shown to affect the expre

58 pesticides PCB180 and bisphenol S may affect sex steroid hormone homeostasis among women of reproduct

59 Altered concentrations of sex steroid hormones, impaired reproductive performance,

60 ip between multiclass organic pollutants and sex steroid hormones in 196 healthy Chinese women aged 2

61 rain neurons are differentially regulated by sex steroid hormones in a dose-dependent manner.

62 sities of neurons that express receptors for sex steroid hormones in a pattern that is remarkably sim

63 Ovariectomy-induced depletion of sex steroid hormones in adult female 3xTg-AD mice signif

64 The influence of sex steroid hormones in both sexes is discussed, as is t

65 The role of sex steroid hormones in the etiology of several diseases

66 and clinical observations suggest a role of sex steroid hormones in the occurrence of meningioma.

67 and their relation to circulating levels of sex steroid hormones in women and to risk of endometrial

68 Associations with nine sex steroid hormones, including progesterone, androstene

69 Together, sex steroid hormone-induced activation of WOX1 and WOX2

70 Sex steroid hormones influence the development of sex di

71 al. show that resistance (insensitivity) to sex steroid hormones is encountered in animals lacking m

72 These results suggest that both absolute sex steroid hormone levels and the rates at which the le

73 Organic pollutant exposure may alter sex steroid hormone levels in both animals and humans, b

74 Sex steroid hormone levels were measured in 24-h urine s

75 We measured plasma sex steroid hormones levels in plasma collected in 1989

76 sical function, frailty, renal function, and sex-steroid hormone levels and seemed to be partially me

77 different between men and women, and female sex steroid hormones likely have a role in this regulati

78 in the interrelationship between endogenous sex-steroid hormone metabolism, risk factors and disease

79 lar and biochemical mechanisms through which sex-steroid hormones modulate memory, and a specific hyp

80 lum has been characterized, the influence of sex steroid hormones on intrinsic cerebellar network dyn

81 was an important mediator of the effects of sex steroid hormones on T47D cell proliferation.

82 Despite the well-known influence of sex steroid hormones on the incidence of cardiovascular

83 recent decades has demonstrated that ovarian sex-steroid hormones, particularly 17beta-estradiol (E2)

84 Genetic variation in genes in the sex steroid hormone pathway is associated with differenc

85 rtium, 874 SNPs in 37 candidate genes in the sex steroid hormone pathway were examined in relation to

86 P<5 x 10(-8)), implicating genes involved in sex steroid hormone pathways (FN1, CCDC170, ESR1, SYNE1

87 ty, lack of physical activity), we also find sex steroid hormones, plasma lipids, and telomere length

88 stem provides a model for the important role sex steroid hormones play in mediating adult neural plas

89 Although age, genetics, and sex steroid hormones play prominent roles in the cause o

90 eca cells to establish a two-cell system for sex-steroid hormone production prior to birth, providing

91 The sex steroid hormone progesterone (Pg) is critically invo

92 idization experiments showed that the female sex steroid hormone, progesterone, decreases steady stat

93 rmones, local growth factors and circulating sex steroid hormones promote pituitary tumor growth and

94 response of the uterine epithelium to female sex steroid hormones provides an excellent model to stud

95 The broad distribution of sex steroid hormone receptors across diverse cell types

96 Sex steroid hormone receptors are expressed in the colon

97 in and support the important role of nuclear sex steroid hormone receptors in modulating social behav

98 leotide polymorphisms (SNP) in genes for the sex-steroid hormone receptors are not strongly associate

99 hemicals (EDCs) due to their ability to bind sex-steroid hormone receptors.

100 Sex steroid hormones regulate various neural functions t

101 Sex steroid hormones released from the gonads play an im

102 nse to infection were related to circulating sex steroid hormones, sex steroid concentrations were ma

103 utable to the direct and indirect effects of sex-steroid hormones, sex chromosomes and epigenetics, p

104 near specific genes with important roles in sex steroid hormone signalling and function, and offer u

105 rtility, with low levels of gonadotropic and sex steroid hormones, small testes or ovaries, impaired

106 ncreased sexual rejection and independent of sex steroid hormone status.

107 Sex steroid hormones such as 17beta-estradiol (estradiol

108 Sex steroid hormones such as estrogen and testosterone h

109 general neuromodulators of memory processes, sex steroid hormones such as the potent oestrogen 17beta

110 ng estrogen receptors.SIGNIFICANCE STATEMENT Sex steroid hormones, such as estradiol, are important r

111 ate a connection between type 2 immunity and sex steroid hormone synthesis in the skin and suggest th

112 n the skin and suggest that abnormalities in sex steroid hormone synthesis may underlie the disrupted

113 Furthermore, targeting sex steroid hormone synthesis pathways may be a therapeu

114 se 1 (HSD3B1), a key rate-limiting enzyme in sex steroid hormone synthesis, predominantly expressed b

115 ed endogenous concentrations of estradiol, a sex steroid hormone that is known to influence UL risk.

116 07, to examine associations between baseline sex steroid hormones, the rate of change in these hormon

117 h the US military did not initiate exogenous sex steroid hormone therapy within 2 years of diagnosis.

118 Biological sex, fluctuations in sex steroid hormones throughout life and gender as a soc

119 Here, we used the cross-sex steroid hormone treatment of transsexuals seeking se

120 tional analyses of caregiving and endogenous sex steroid hormones were also conducted.

121 Use of exogenous sex steroid hormones, when indicated, may improve outcom

122 asonal fluctuations in circulating levels of sex-steroid hormones, which are known to be potent neuro