ライフサイエンスコーパス: sharpen

1 ncements: auto-contrast, emboss, invert, and sharpen.

2 sion 1.2 the description of the elements was sharpened.

3 d when OS of their spiking responses becomes sharpened.

4 ed, and its spatial tuning profile gradually sharpened.

5 ical excitatory inputs to a L4 neuron became sharpened.

6 s also provide a practical guide for optimal sharpening.

7 hreshold, the singular structure at its apex sharpens abruptly.

8 ynamic maps had a reduced surface area (were sharpened) after CSD.

9 tation with an intrinsic frequency acting to sharpen and adjust the location of the resonant peak.

10 This study helps to sharpen and define a mechanistic understanding of patter

11 excitation, enabling sensory features to be sharpened and represented by sparse codes.

12 ed that perceptual learning is due to either sharpening and amplification of tuning curves in early v

13 rd signaling of EphA4 is required for border sharpening and induction of boundary cells in the zebraf

14 t al.'s arguments in the target article need sharpening and rethinking at both mechanistic and evolut

15 In this case, our model predicted reduced sharpening and strength of inverted disparity tuning.

16 This alternation between sharpening and transition occurs repeatedly within indiv

17 domain 4 peptide, the M632 resonance of UvrB sharpens and shifts to a position consistent with a UvrB

18 The wave sharpens and slows as it advances and may never reach st

19 dition to amplification, vM1 activation also sharpened angular tuning of vS1 neurons in all cortical

20 ers in humans presents a rich opportunity to sharpen animal models of eating disorders and to identif

21 The resultant gain and frequency sharpening are necessary for speech discrimination, part

22 This selectivity itself seems to sharpen as a sentence unfolds.

23 dditionally, hybridization activity profiles sharpen as the spacing between probes increases, indicat

24 ast between the W-rich layer and the bulk MP sharpens as the latter becomes more organic, while the W

25 es in energy (3.54 eV, 3.26 eV, 3.04 eV) and sharpens as the size of the QD increases (fwhm = 207 meV

26 er from paramagnetism to ferromagnetic order sharpens as the system is scaled up, prefacing the expec

27 s of the Drosophila larva and show that they sharpen at lower odor doses.

28 and calyces (postnatal days (P)1-P4), tuning sharpened at each stage.

29 inuously growing at the forming end and self-sharpening at the mature grinding tip.

30 et highly selective neuron subtypes, thereby sharpening attainable links between neuron type, behavio

31 a FFAd, human form perception is transiently sharpened because "blur" signals are mitigated.

32 Importantly, spatial tuning was not sharpened between A1 and CL in aged monkeys as it is in

33 ith the flanking meso-aryl groups leads to a sharpened, blue-shifted wavelength lambdamax band, bucki

34 ressly pragmatic and tentative: he sought to sharpen boundaries for didactic reasons and to develop d

35 gion that is being reconstructed, and it can sharpen boundaries.

36 Angle tuning sharpened, but only in neurons that preferred trained an

37 e that the accuracy of scene segmentation is sharpened by a suppressive process that resolves local a

38 ingent on attentional engagement and in fact sharpened by top-down expectation.

39 ed by statistically-unstable mixing and self-sharpening, by boundary-induced internal gravity waves;

40 RNA polymerase III, we illustrate how local sharpening can increase interpretability of density maps

41 aturation fusion method often applied for EM-sharpening can result in serious image artifacts, especi

42 recise specification of muscle cell types by sharpening cellular responses to Hedgehog.

43 te the physical barrier of the cell membrane sharpens chemical gradients across the cell.

44 nd near-linearity for preferred combinations sharpened combination tuning relative to linearly predic

45 ntly to advance resilience research, both by sharpening concepts and theories and by conducting empir

46 Interfacial sharpening, controlled by the Flory chi parameter and mo

47 h integration best explains the experimental sharpening data.

48 nd inhibition is a neural mechanism that can sharpen desired movement by inhibiting unwanted movement

49 , and their underlying neural circuits, will sharpen diagnostic precision and understanding of risk f

50 results in broadened orientation tuning and sharpened direction tuning in a stimulus-selective subpo

51 Our results indicate that, rather than sharpening directional selectivity per se, these circuit

52 dent extraction of orientation and direction sharpens directional tuning through surround inhibition

53 atform that establishes a common language to sharpen discussion across the Earth Science community.

54 The voltammetric response sharpens dramatically as the temperature increases, beco

55 e frequency tuning of neuronal ensembles was sharpened due to both increased gain at the preferential

56 of visual cortical neurons is progressively sharpened during development.

57 wn macroscopic gradient of prior knowledge's sharpening effect on neural representations across the c

58 category boundary, suggesting a categorical sharpening effect.

59 This "blur-sharpening" effect allows selectivity conveyed by excita

60 ely, BMP gain-of-function experiments caused sharpened expression boundaries of extra-embryonic targe

61 ndividual differences in cognitive aging has sharpened focus on identifying biological factors underl

62 ly, during the last decade, there has been a sharpened focus on the convergence of metabolism and imm

63 The sharpening focus on global health and the growing recogn

64 how that adaptation to stimulus dynamics can sharpen form perception.

65 passive mechanics within the organ of Corti sharpen frequency selectivity by defining which OHCs enh

66 cochlear amplification does not appreciably sharpen frequency tuning for cochlear regions that respo

67 that increase the amplitude of vibration and sharpen frequency tuning, the data have typically been l

68 ad frequency range and did not substantially sharpen frequency tuning.

69 beta57, beta135) conferring T1D risk should sharpen functional and translational studies.

70 weaknesses, which synergize when combined to sharpen gene expression boundaries.

71 We demonstrate greatly sharpened global and gene-specific differential expressi

72 Self-sharpening helps explain phenomena such as ultra-long ru

73 sited in the Protein Data Bank and show that sharpening improves the electron density map in many cas

74 r (L)2/3, but not L4, excitatory neurons was sharpened in the presence of sound or optogenetic activa

75 ections, results in the apparently normal OS sharpening in excitatory neurons.

76 place in two distinct stages: representation sharpening in the early visual areas and competitive int

77 We revealed a distinct sharpening in TSS utilization in genes upregulated in sl

78 tivity could recapitulate in cis the kinetic sharpening (increased onset and deactivation rates) and

79 graph-based semi-supervised learning, graph sharpening integration, composite association network, B

80 To sharpen intuition about possible mechanisms underlying t

81 Sharpening is a powerful method to restore the details f

82 We find that this sharpening is achieved by dismantling the binocular circ

83 Sharpening is evident for both trained and untrained sti

84 l and imaging studies are included when they sharpen issues or reveal underlying mechanisms.

85 that GABAB modulation of synaptic input can sharpen ITD selectivity.

86 this linguistic pressure on pitch appears to sharpen its neural encoding and can lead to perceptual b

87 Furthermore, increasing the intensity sharpens lemniscal receptive field profile as adaptation

88 ditional orthographic representations, which sharpen lexical representations and facilitate the retri

89 form and adapted to a precise fit, with self-sharpening lower molar cusps.

90 that a routine practice of electron density sharpening may have a broad impact on the outcomes of st

91 to help overcome viscous forces and thereby sharpen mechanical tuning of the sensory cells.

92 This vibrating probe is an insulated, sharpened metal wire with a small platinum-black tip (10

93 otinic activation within glomerular circuits sharpens mitral cell chemoreceptive fields, even in the

94 at nicotinic cholinergic receptor activation sharpens mitral cell chemoreceptive fields, likely via i

95 ropose a country-led, data-driven process to sharpen national health plans, seize opportunities to ad

96 xperiences may interact over time to sustain sharpened neural processing in central auditory nuclei w

97 ired from fast, one-shot perceptual learning sharpens neural representation throughout the ventral vi

98 l. (2016) demonstrate that presence of sound sharpens neural tuning in the primary visual cortex via

99 Attention elevates neural responses and sharpens neural tuning to the attended feature, as shown

100 rons in the mouse primary visual cortex (V1) sharpens neuronal feature selectivity and improves perce

101 This coupling results in a sharpened NMR line width relative to a GaCu analogue, in

102 rization, our method sharpens signal without sharpening noise and can remarkably increase both the dy

103 Spatial sharpening occurred on a scale of tens of seconds and co

104 ared with idle conditions, with the greatest sharpening occurring during the location-relevant task.

105 impairment in the functional and structural sharpening of an inhibitory tonotopic map, as evidenced

106 al and default mode networks exhibit similar sharpening of content-specific neural representation, bu

107 , we introduce a general procedure for local sharpening of cryo-EM density maps based on prior knowle

108 hanges of each component can account for the sharpening of excitatory input tuning remains unclear.

109 uning was not required for the developmental sharpening of excitatory tuning but did precede binocula

110 about the cortical processes underlying the sharpening of feature selectivity.

111 ncy increased, reflecting increased temporal sharpening of inputs by the olfactory bulb.

112 4 but are driven by the experience-dependent sharpening of ipsilateral eye responses.

113 ions, we provide a mechanistic model for the sharpening of MC receptive fields by nAChRs, which could

114 et al. show that category training leads to sharpening of neural responses in high-level visual cort

115 (20 mM) attenuated the neostigmine-dependent sharpening of ORFs.

116 he input dynamic range and caused additional sharpening of output responses beyond unselectively supp

117 hyperphosphorylation and endocytosis) allow sharpening of PCP signaling locally on the tips of the f

118 ing facilitated perceptual processing or the sharpening of perceptual representations.

119 gions resulted in both the amplification and sharpening of responses at attended time points, in esse

120 Increasing noise disrupts sharpening of rhombomere boundaries and proper patternin

121 as shorter and faster, reflecting a temporal sharpening of sensory inputs.

122 nsistent with a slow-speed prior) and scale (sharpening of similar features).

123 cending auditory pathway as a consequence of sharpening of spatial sensitivity and increasing forward

124 from these studies was a new way to achieve sharpening of specific peaks in the CE separations of pe

125 al changes remain an untapped source for the sharpening of such warning signals.

126 This sharpening of taste selectivity was specifically attribu

127 t: increases in spike rate (rate coding) and sharpening of the coincidence of spiking in active neuro

128 The latter phase is accompanied by a sharpening of the excitatory but not inhibitory frequenc

129 ed frequencies of the cell and a significant sharpening of the frequency tuning of membrane responses

130 Sharpening of the GEAn(+*) transient absorption and a sh

131 ic phonon propagation coincides with unusual sharpening of the longitudinal acoustic mode due to a lo

132 n accurate representation of body dyads with sharpening of the representation of single-body postures

133 ned with excitation, and leads only to minor sharpening of the spectral response properties.

134 put to layer (L)4 neurons contributes to the sharpening of their frequency selectivity during postnat

135 A sharpening of tuning is accomplished locally at the expe

136 iculate pathway to achieve context-dependent sharpening of visual representations.

137 ge fusion through several applications: (i) 'sharpening' of IMS images, which uses microscopy measure

138 mitral cell firing rates and hence does not sharpen olfactory representations under a rate metric.

139 The implementation of a comb filter and peak sharpening option is also demonstrated to be highly effe

140 pattern of results in support of either the "sharpening" or "dampening" model.

141 [2-5], and feedback has been demonstrated to sharpen orientation tuning of neurons in the primary vis

142 creased spiking of PV+ interneurons markedly sharpened orientation tuning and enhanced direction sele

143 Learning improved neural discriminability, sharpened orientation tuning, and led to higher contrast

144 itory tuning is critical for maintaining and sharpening OS at high contrast.

145 g of the inhibitory tuning is sufficient for sharpening OS.

146 nhibition may improve spatial resolution and sharpen other forms of selectivity in rodent lateral gen

147 To help sharpen our ability to discriminate patients with hippoc

148 s, our research and clinical agenda needs to sharpen our lens on the fundamental importance of our pa

149 eart disease, and review techniques that can sharpen our understanding of cardiovascular biology.

150 and cell types in different conditions will sharpen our understanding of how and why cells regulate

151 1) We must sharpen our understanding of which elements of religious

152 e sequencing (scWES) has deeply expanded and sharpened our knowledge of cancer evolution and subclona

153 Sharpening our focus on deliberate decision making offer

154 The following tasks remain: (a) sharpening our understanding of which elements of religi

155 Practice sharpens our perceptual judgments, a process known as pe

156 eld commercially viable devices, but it also sharpens our understanding of the design problems solved

157 single location, the representation of which sharpens over the course of several milliseconds, as the

158 e first demonstrate that the contents of LTM sharpen perceptual sensitivity for targets presented at

159 Additionally, attention could sharpen position tuning at the neural population level,

160 ual mechanism involving both signal gain and sharpened position tuning would be highly efficient at i

161 onal sputter erosion, field-directed sputter sharpened probes have smaller radii and produce lithogra

162 ces a mobility shift that acts to enrich and sharpen protein fronts as proteins enter the microchanne

163 remained unchanged, resulting in an overall sharpening rather than a weakening of OS.

164 r stimuli, complex stimuli revealed markedly sharpened receptive fields, largely as a result of adapt

165 in the visual thalamus but are essential for sharpening receptive field properties and improving cont

166 eractions among neuronal subtypes ultimately sharpen recurrent excitation, producing specific and rel

167 ynaptic circuit mechanisms underlying the OS sharpening remain unclear.

168 The ability to sharpen representation of repeating elements is crucial

169 rcement learning signals in the striatum and sharpen representations of associative values in prefron

170 hat representations in A1 change not only to sharpen representations of task-relevant stimuli but als

171 porating these factors (plus inequality) can sharpen researchers' predictions.

172 ls as opposed to increasing response gain or sharpening response spectra.

173 Sharpening resulted primarily from increased suppression

174 hese results suggest that dLGN maintains and sharpens retinal direction selectivity and integrates op

175 pally subtract from excitatory responses and sharpen selectivity.

176 e, while feedback inputs to apical dendrites sharpen selectivity.

177 aphy in human observers (men and women) that sharpened selectivity for a particular color arises from

178 We conclude that attention sharpens selectivity over time by attenuating the respon

179 ces associated with a rhythmic motor routine sharpen sensory representations, enacting auditory 'acti

180 ly simulated by a Prediction Error and not a Sharpened Signal model.

181 ugh wavelet-basis regularization, our method sharpens signal without sharpening noise and can remarka

182 Computational simulations of Sharpened Signals and Prediction Errors during speech pe

183 uish representations of Prediction Error and Sharpened Signals in other perceptual domains.

184 ced or sharpened via interactive activation (Sharpened Signals).

185 We show that signal inactivation sharpens signals, reducing variability in the arrival ti

186 he units recorded in A1 showed substantially sharpened spatial tuning during the behavioral tasks as

187 nd we did not find evidence that Ntsr1 cells sharpen spatiotemporal filtering.

188 dynamic catch-and-release mechanism used to sharpen spatiotemporal signals mediated by diverse senso

189 might contribute to memory consolidation by sharpening specificity of subsequent synaptic input and

190 ances the fidelity of spike transmission and sharpens spike timing.

191 h-sealing and experimentally challenging tip-sharpening steps used in conventional fabrication protoc

192 t, suppression was not tuned and appeared to sharpen stimulus selectivity.

193 To examine the role of the inhibition in sharpening stimulus selectivity, we have quantitatively

194 h a DUB prevents undesired ubiquitination to sharpen substrate specificity for an associated ubiquiti

195 dicted that this reduces spike latencies and sharpens suprathreshold responses in BCs, which we verif

196 These changes served to sharpen taste selectivity, mainly by reducing responses

197 a novel biased-probe field-directed sputter sharpening technique applicable to conductive materials,

198 of inhibitory interactions normally used to sharpen temporal processing of sensory inputs.

199 , the cursor's motion on the screen, did not sharpen the accuracy of joint-action cells' representati

200 ry actions impact health outcomes, we aim to sharpen the analytic distinctions between studies that d

201 erplay of experiment and theory in ways that sharpen the conclusions of both and animate future studi

202 al inhibition between pain and itch may help sharpen the distinction between these sensations.

203 d the hippocampus is thought to classify and sharpen the distinctions between these events.

204 Our analysis helps sharpen the dramatic difference between laboratory and w

205 Instead, a primary function may be to sharpen the dynamic range of gene expression changes dur

206 als along monaural pathways, and bushy cells sharpen the encoding of fine structure and feed binaural

207 that in vertebrates; in vertebrates, miRNAs sharpen the first developmental transition, whereas in p

208 lear amplifier, serving to localize and thus sharpen the frequency region of amplification.

209 -in this highly columnar cortex-task demands sharpen the frequency tuning in superficial cortical lay

210 ensitivity and low selectivity can laterally sharpen the frequency tuning of neurons, ensuring their

211 pport a "switch-like" response that helps to sharpen the ind dorsal boundary.

212 However, aPKC helps to sharpen the pattern of Miranda, by keeping it off the ap

213 These results sharpen the picture of the mechanical unfolding of membr

214 y engaging complementary neural resources to sharpen the precision of the task-relevant object in mem

215 into grid cell models, we show that they can sharpen the precision of the temporal code and enhance t

216 etabolic steps with stoichiometric models to sharpen the prediction of intervention strategies for im

217 ory signals to vS1 that serve to amplify and sharpen the response of neurons in the barrel cortex to

218 The findings sharpen the scientific question about how variation in t

219 est that the net effect of L4 activity is to sharpen the spatial representations of L5 neurons.

220 s interactions provides a novel mechanism to sharpen the specificity of cell-cell interactions.

221 y and inhibitory inputs respectively greatly sharpen the spike latency tuning and expand its dynamic

222 intain the interareal stimulus signaling and sharpen the stimulus representation by gamma-synchronize

223 arkedly reduce the discharge probability but sharpen the temporal precision of action potential gener

224 VgrG-like partners show that these proteins sharpen the tip of the T6SS spike complex.

225 1), so-called "sideband" inhibition helps to sharpen the tuning of local neuronal responses.

226 e 2014-2016 global coral bleaching event has sharpened the focus on such interventionist approaches.

227 anticholinesterase drug neostigmine (20 mM) sharpened the ORF responses of mitral cells.

228 The conductance-dependent suppression also sharpened the STDP curve, with reliable synaptic potenti

229 oved the quality of temporal predictions and sharpened the temporal selection of relevant auditory in

230 and lower gain at intermediate frequencies, sharpening the high-frequency resonance.

231 lification enhances frequency selectivity by sharpening the peaks of cochlear traveling waves and con

232 e of receptive fields, therefore potentially sharpening the perception of space.

233 an important role in cerebellar function by sharpening the precision of Purkinje cell spike output.

234 i activity suppresses alternative responses, sharpening the response profile and encouraging exploita

235 tate attention and goal-directed behavior by sharpening the sensory representation of goal-relevant s

236 Several factors are sharpening the tension between the supply and demand for

237 he C-lobe of CaM in the presence of Ng, thus sharpening the threshold for the C-domain to become Ca(2

238 VI in "matched" (homologous) barrel columns sharpens the angular tuning curves of single VPM neurons

239 nism: the presence of competitors shifts and sharpens the Ca2+ frequency-dependence of CaM binding pr

240 This work sharpens the conceptual rationale for therapeutic target

241 mbers effectively integrates information and sharpens the discrimination of fine differences.

242 ing and an activator of the Wnt pathway that sharpens the distinction between opposing Wnt and Notch

243 It sharpens the need to accept the view that there is more

244 s is consistent with the view that attention sharpens the neural responses that are elicited by the t

245 irectionality of channel gating considerably sharpens the neuronal frequency selectivity at the perip

246 omechanical filter process that considerably sharpens the neuronal response.

247 KZip(+) significantly sharpens the precision of neuronal genetic control avail

248 Feedforward inhibition sharpens the precision of neurons throughout ascending a

249 und suppression in a manner that effectively sharpens the priority map.

250 We conclude that long-term familiarization sharpens the response dynamics of neurons in both monkey

251 Scap/cholesterol/Insig interactions further sharpens the sensitive switch that exerts precise contro

252 alcium concentration close to the source but sharpens the spatial and temporal calcium gradients.

253 This dynamically sharpens the spatial focus of the receptive field and in

254 natomic arrangement boosts the amplitude and sharpens the time course of excitatory postsynaptic pote

255 tion is a fundamental circuit operation that sharpens the tuning properties of cortical neurons.

256 nalyses suggest 1) that surround suppression sharpens the visual responses in V1 to a stationary scen

257 However, since reducing hyperfine fields sharpens the Zeeman peak at the cost of an increased zer

258 Neurons in the visual cortex sharpen their orientation tuning as humans learn aversiv

259 nocular neurons in the primary visual cortex sharpen their receptive field tuning properties.

260 ear acquisition, hippocampal CA1 place cells sharpen their spatial tuning and dynamically change spat

261 naptic tuning as an additional mechanism for sharpening their frequency selectivity.

262 cessing in A1 supragranular-layer neurons by sharpening their receptive fields and frequency tuning,

263 hibition transforms olfactory bulb output to sharpen these dynamics.

264 Further studies are warranted to further sharpen this instruments validitity and general clinical

265 of the vgat gene throughout the TMN further sharpened this phenotype.

266 However, boundaries can also sharpen through cellular plasticity, with cell fate chan

267 In some cases, domain boundaries sharpen through differential adhesion-mediated cell sort

268 cal inhibition, frequency selectivity can be sharpened through temporal integration, thus supporting

269 the corners and edges of the nanocubes were sharpened through the introduction of Br(-) as a regulat

270 der range of ISIs, whereas inhibitory tuning sharpened to form a perceptual boundary.

271 nization will be reshaped, repositioned, and sharpened to match the object's shape and scale.

272 ened beyond recognition at high field can be sharpened to narrow peaks in the low-field dimension.

273 transduction current increases, sensitivity sharpens, transduction occurs at smaller hair-bundle dis

274 g nor plasticity is sufficient on its own to sharpen transition regions between different rhombomeres

275 ir effects on vibration are small and do not sharpen tuning.

276 holds at the calyceal spike initiation stage sharpened tuning and advanced response phase.

277 These neurons further exhibit sharpened tuning for pup vocalizations following materna

278 esis that social fear generalization prompts sharpened tuning in the visuocortical representation of

279 We speculate that sharpened tuning of neuronal representations may cause r

280 in social situations also showed heightened sharpened tuning of visuocortical neurons to facial iden

281 ling a smaller range of best frequencies and sharpening tuning.

282 For example, we describe how inhibition sharpens tuning for spatial and temporal features of the

283 to obtain food rewards; the current findings sharpen understanding of the boundaries of cottontop tam

284 nt spread function at 2.2-mum wavelength was sharpened uniformly to 0.3'' over a field of at least 2'

285 fire cycles, as boundaries are progressively sharpened until flammability appears to respond in a thr

286 lasticity, and their combination in boundary sharpening using multi-scale, stochastic models.

287 e N-oxide, possessing a slightly shifted and sharpened UV-vis spectrum (lambdamax = 737 nm).

288 ir orientation discrimination, mirroring the sharpened V1 orientation tuning.

289 ctions from turbulent diffusion theory, self-sharpened velocity and concentration profiles and a stab

290 features of the speech input are enhanced or sharpened via interactive activation (Sharpened Signals)

291 Here, we examine in male volunteers how sharpened visual processing is affected by fear extincti

292 e found that generalization of social threat sharpens visuocortical tuning of social threat cues, whe

293 rget flanked by distractors, consistent with sharpened visuospatial perceptual representations.

294 t fundamental sensing limits are necessarily sharpened when the need to communicate information is ta

295 We tested the hypothesis that spatial tuning sharpens when an animal engages in an auditory task.

296 onse onset, and receptive fields dynamically sharpen while suppression strength increases.

297 In L2/3, enrichment strengthened and sharpened whisker point representations, and created fun

298 Enrichment (P21 to P46-71) sharpened whisker tuning and decreased, but did not abol

299 's stretch band moves to lower frequency and sharpens with freezing, and the bending band goes to hig

300 hile the timing of rhythmic excitatory drive sharpens within the pool as speed increases, there are s