ライフサイエンスコーパス: shear

1 ed by erosion and restructuring by the fluid shear.

2 rom a high to low affinity state under fluid shear activated phospho-Syk- and ADAM17-mediated proteol

3 assisted force spectroscopy, peel and static shear adhesion.

4 convergence, increased instability, and wind shear, all factors that strengthen organized convection.

5 nergy and stresses in terms of invariants of shear and area deformation.

6 ling surface Rayleigh waves to reversed bulk shear and compressional waves independently, thereby cre

7 ric state emerges, which is characterized by shear and concentration banding at the polar/isotropic i

8 establish upper bounds for the values of the shear and dilatational viscosities.

9 alculating the attractive DLVO-force and the shear and drag forces acting on a bacterium near collect

10 addition, standard lattices have well known shear and fatigue weaknesses due to their periodic basis

11 is induced by laminar, but not oscillatory, shear and inducible, endothelial-specific deletion impai

12 itions, operating two distinct flow regimes (shear and inertial) which can expose subtle mechanical p

13 uring biting and chewing - dorsoventral (DV) shear and lateral transverse bending ('wishboning').

14 and emphasize the importance of hydrodynamic shear and membrane surface properties on the initially d

15 including transient and steady-state simple shear and planar elongational flows.

16 siological levels of shear stress, with both shear and the Piezo1 agonist Yoda1 increasing the number

17 the conduit, this plug becomes progressively sheared and weakened until gas enriched in the least sol

18 Chaperone networks are required for the shearing and generation of transmissible propagons from

19 spectral encoding, pulse splitting, temporal shearing, and compressed sensing-enabling unprecedented

20 ear zones, which results in further speedup, shearing, and weakening, hence promoting additional dama

21 SDS-PAGE and MS analysis revealed that the sheared archaella are composed principally of two of the

22 he bed, but above a threshold velocity, till shears at its rate-independent Coulomb strength.

23 Increasing the indentation depth revealed shear band suppression which is related to a homogenous

24 This transformed behaviour suppresses shear-banding in bulk samples in normal uniaxial (tensil

25 s to extreme localization of plastic flow in shear bands, and is associated with early catastrophic f

26 r chains by using a simple one-step solution-shear/bar coating technique.

27 ynamic ocean topography, and (3) geostrophic shear (between S and N) due to horizontal gradient of de

28 at the geoid undulation (N), (2) geostrophic shear (between S and N) due to horizontal gradient of dy

29 nd experimental dental adhesives in terms of shear bond strength and microtensile bond strength (uTBS

30 aining dental adhesives generated equivalent shear bond strength and uTBS in comparison with the cont

31 n and proximity ligation, followed by gentle shearing, ChIP, biotin capture and paired-end sequencing

32 The shear complexity of SOM, an inseparable mixture of thous

33 nd to have a more prominent influence on the shear components than the normal components along the di

34 etention of senescent erythrocytes under low shear conditions was found to result in steady shrinkage

35 eformability of RBCs when examined under low-shear conditions, despite obvious decrement of cellular

36 Total length of molar shear decreased with wear, suggesting a dietary shift du

37 This shear-dependent behavior of the platelet aggregate forma

38 ction and steeper contraction angle showed a shear-dependent occlusion and lag time for both PRP and

39 ch synchronize the electrically powered self-shearing directions.

40 served rapid cross-frontal mixing occurs via shear dispersion, generated by frontal instabilities and

41 and the second component (i.e., geostrophic shear due to horizontal gradient of dynamic ocean topogr

42 tes that mDC loses sensitivity to changes in shear elasticity when the offset distance exceeds 5 mum,

43 ned relationships between the cell diameter, shear elasticity, and offset distance were used to estab

44 of cellular mechanical properties (diameter, shear elasticity, cortical tension) and initial cell pla

45 ically alter cell deformability (i.e., prior shear exposure (PSE) to 100 Pa x 300 s).

46 These findings indicate that shear exposure and stress-strain history can alter subse

47 l blood trauma-induced by supraphysiological shear exposure-paradoxically increases the deformability

48 l as a key TM transducer of tensile stretch, shear flow and pressure.

49 riction-based deformability cytometry (cDC), shear flow deformability cytometry (sDC) and extensional

50 Piezo1-dependent control of shear flow sensing, calcium homeostasis, cytoskeletal dy

51 ought to explore RBC mechanical responses in shear flow using purpose-built laser diffractometry in t

52 ocity leads to the strongest acceleration, a shear flow with a linear velocity gradient can cause fus

53 Under increased shear flow, pre-existing clusters of cells disaggregate,

54 Under high shear flow, soluble agonist released by platelets was li

55 actile activity and of an externally imposed shear flow, we find three possible morphologies.

56 RBC membrane usually experiences under high shear flow.

57 Also, shearing flow testing showed shear-thinning and thixotro

58 subsequent viscoelastic responses to various shear flows.

59 RBC behavior in physiologically relevant low-shear flows.

60 ant (p < 0.05) effect of PEF was observed on shear force (N) and toughness (N/mm s) of the products,

61 ed by alpha-, beta-, and gamma-subunits is a shear force (SF) sensor and a member of the ENaC/degener

62 which switch into each other in response to shear force and solvent vapors, are presented and their

63 pproached to the sample by either current or shear force feedback, and the physical resolution of the

64 is more sensitive to gel-sample contact than shear force feedback.

65 mum for current feedback and ca. 63 mum for shear force feedback.

66 When the shear force is small, the transport speed of microorgani

67 signals from collagen and blood flow-induced shear force to activate G protein 13 signaling for plate

68 (p < 0.05) higher soluble collagen and lower shear force values.

69 ical controlling threshold of internal water shear force was obtained as [0, 0.20] [0.35, +infinity]

70 When there is a relatively large shear force, it is favorable to the transport and renewa

71 ood perfusion studies demonstrated GPR56 and shear-force dependence of platelet adhesion to immobiliz

72 s GPR56 as an initial collagen responder and shear-force transducer that is essential for platelet sh

73 le protein complex responsible for resisting shear forces and adhering bacteria to cellulose fibers i

74 We hypothesized that the large shear forces exerted on circulating cells, particularly

75 an impermeable and a semipermeable state by shear forces occurring in flow or during turbulent mixin

76 Besides, the influence of water shear forces on biofilms is dual.

77 Water shear forces play a vital role in the formation, develop

78 exture of the substrate, creating retrograde shear forces that are sufficient to drive the cell body

79 rturbations such as coughing, which generate shear forces that exceed the ability of non-covalent bon

80 an environment of open blood circulation and shear forces unlike other lymphoid organs.

81 ar forces, this paper considered 8 different shear forces with a range of [0, 0.7]Pa on the inner sur

82 aintain bacterial attachment that withstands shear forces within the human host.

83 n mechanism of biofilm under different water shear forces, this paper considered 8 different shear fo

84 antly subjected to compressive, tensile, and shear forces, which regulate nucleoskeletal and cytoskel

85 of electrophoretic drag and electro-osmotic shear forces.

86 ng constraint and compression, pressure, and shear forces.

87 anges in normal stress, demonstrate that the shear frictional resistance exhibits a significant lag i

88 grees XY-cut with a thin SiO(2)-cover layer, shear horizontal surface acoustic waves (SAW) are excite

89 Cell suspensions were sheared in a stepwise manner (between 0.3 and 5.0 Pa), w

90 Shear-induced aggregation is not currently considered in

91 g delivery, diagnostics, tissue engineering, shear-induced gelation, and functionally engineered rheo

92 he perpendicular drive pulse, similar to the shear jamming of granular systems.

93 lane of hexagonal lattices prompt repetitive shear-like deformations of the solitons, which synchroni

94 eletal filament architectures that result in shear-like pulling geometries.

95 ater mechanical stability of the complex for shear-like than for zipper-like pulling configurations.

96 eling', as opposed to the more conventional 'shearing' mechanism of the parent ferrocene, leading the

97 The molecular picture of a key shear-mediated DNA-protein interaction is provided here

98 This is the first in situ demonstration of shear-mediated SC mechanobiology as a key IOP-sensing me

99 ) cartilage samples to determine the dynamic shear moduli (G*, G' G") of the tissues.

100 ymerization yields predictable low-frequency shear moduli ca. 10-100 kPa, well below values typical o

101 the cornea must be described by at least two shear moduli, contrary to current single-modulus models,

102 We assessed the soleus H-reflex, shear modulus (ultrasound elastography) and vascular ind

103 e wave speed and IOP between 13-18 mmHg, and shear modulus decreases with age (- 0.32 +/- 0.17 m/s pe

104 Here, we report the first measurement of shear modulus in human corneas in vivo using optical coh

105 ed was 7.86 +/- 0.75 m/s, corresponding to a shear modulus of 72 +/- 14 kPa.

106 retical yield strength (G/24, where G is the shear modulus of a material) and homogeneous plastic str

107 aw [Formula: see text] for the low-frequency shear modulus of liquids as a function of the confinemen

108 From the complex shear modulus output generated by mf3D-MRE, the damping

109 We also explore the discrepancies among shear modulus values measured using different experiment

110 The initial shear modulus values we obtain using our current model (

111 We generalize an expression of the initial shear modulus, which is independent of the number of mol

112 g in amorphous solids subject to oscillatory shear near the onset of plastic deformation, and of the

113 No significant cell shearing of uveal melanoma cells occurred in vitro with

114 The model shows that changes in pressure or shear on the plate can be used to infer the location and

115 hen exposed to even low levels of mechanical shear once present in their liquid-liquid phase separate

116 amined microcirculatory fluid flow via video shearing optical microscopy, and O(2) distributions via

117 The key ingredient is to produce strong shear or strain around the sphere, which requires carefu

118 strain profiles in various tactile motions (shear, pinch, spread, torsion, and so on).

119 stretching (PS) effects on blood flow ( Q ), shear rate ( Y ), and vascular function in the feeding a

120 ) mmHg(-1) ; 95% CI = -0.0 to -0.4) and mean shear rate (-21.9 s(-1) ; 95% CI = -5.8 to -38.0; all P

121 e-C47 product decreased with the increase in shear rate and declined by increasing the temperature up

122 ophobic membranes, but much higher under low shear rate and much lower under high shear rate, for the

123 eer bacterial and archaeal diversity was the shear rate and the membrane surface properties, respecti

124 ed a microfluidic system to recapitulate the shear rate conditions before and after TAVI.

125 h different surface properties and under two shear rate conditions without filtration.

126 However, the influence of margination and shear rate on occlusive clot formation is not fully unde

127 asured under filtration mode and at a higher shear rate showed a similar trend.

128 always occurs given enough time-whereas the shear rate threshold observed under flow is a genuine ph

129 lica) = 0.20 via a heating module with lower shear rate to reduce the Pe < 1.

130 For intermediate activity and shear rate, an asymmetric state emerges, which is charac

131 der low shear rate and much lower under high shear rate, for the hydrophilic membrane.

132 nd hypermia, with consequent fluctuations in shear rate, occuring during repetitive passive stretchin

133 ying the intensity of the active forcing and shear rate.

134 nt role of tissue factor, independent of the shear rate; (3) a mechanism of tissue factor-enhanced ac

135 elet-rich plasma (PRP) were perfused at high shear rates (> 3,000 s(-1)) through two microfluidic sys

136 activity, platelet plug formation under high shear rates (PFA), and ristocetin-induced platelet aggre

137 Occlusive thrombi formed under high flow shear rates develop very rapidly in arteries and may lea

138 ition experiments, was similar under the two shear rates for the hydrophobic membranes, but much high

139 shear thinning behaviour to gelatine, within shear rates ranging from 25.8 to 129 (s(-1)).

140 nhibitory effects are compromised under high shear rates when VWF levels are increased.

141 For low shear rates, a simple lamellar state is obtained.

142 series of tissue factor patch sizes or wall shear rates.

143 ingle-modulus models, decoupling tensile and shear responses.

144 uses containing a functional fragment of the shear-responsive endothelial nitric oxide synthase (eNOS

145 ide-angle X-ray scattering, and steady-state shear rheology measurements.

146 Here, we combine shear rheology of reconstituted collagen networks with c

147 Shear rheology to first characterize the effect of thiol

148 phologies were also confirmed by oscillatory shear rheology.

149 Additionally, shear rheometry was combined with Transition State Theor

150 how viscoelastic properties, as measured by shear rheometry, are linked to the molecular behavior of

151 ading to an effective increase of the liquid shear rigidity.

152 quantify fault valving through 2-D antiplane shear simulations of earthquake sequences on a strike-sl

153 e can be generalized as "tensile-rupture and sheared-sliding" (TRSS).

154 of deep tension cracks on the top, and then shearing slip along the bottom.

155 numerical simulations, we computed the fluid shear, solid stresses and the stress ratio at the the bi

156 amounts of solvent with high-energy mixing, shearing, sonication or electrochemical treatment(1-3).

157 by mf3D-MRE, the damping ratio at 40 Hz and shear stiffness at 60 Hz best correlated with NASH.

158 gnetic resonance elastography (3D-MRE), with shear stiffness measured at 60 Hz, damping ratio at 40 H

159 alterations in whole blood viscosity and the shear stimulus.

160 rain transfer mechanisms can accommodate the shear strain carried by slip bands and mechanical twins

161 rence in the rupture velocities, MLS-derived shear strain fields are remarkably similar at the two si

162 lized lattice rotation that accommodates the shear strain in the incoming band, preventing the build-

163 c band structure is caused by a photoinduced shear strain in the Te film that breaks the screw symmet

164 The greatest variability in both shear strength and roughness exists for joint samples wi

165 hat accurately predicts grain size-dependent shear strength in the inverse Hall-Petch regime.

166 act temperature, and reducing its frictional shear strength.

167 and laser-derived deformability at any given shear stress >=1 Pa.

168 igh shear stress (before TAVI) and under low shear stress (after TAVI).

169 he activation status of monocytes under high shear stress (before TAVI) and under low shear stress (a

170 nse mechanical cues by changes in fluid flow shear stress (FFSS) across their dendritic projections.

171 adient across the stenosis (DeltaP) and wall shear stress (WSS) - by performing the largest simulatio

172 The combined role of wall shear stress (WSS) and circumferential wall stresses (CW

173 dothelial cells (ECs) to acute arterial wall shear stress (WSS) in the arterial circulation, and the

174 men volumes, maximal wall pressure, and wall shear stress [WSS]) to identify relevant parameters for

175 nthase (eNOS) promoter, we tested effects of shear stress and elevated flow rate on reporter expressi

176 hanically stimulated rat cortical neurons by shear stress and local indentation.

177 ity and actin disruption induced by Yoda1 or shear stress and prevented Piezo1-induced monocyte adhes

178 IH reduced vascular shear stress and steepened the relationship between dias

179 The magnitude of the reduction in the shear stress and the local friction coefficients have be

180 Reductions in vessel wall shear stress and, consequently, nitric oxide production

181 Thus, deleterious effects of shear stress are initiated by Piezo1 but require TRPV4.

182 eas they exhibit progressive increase in the shear stress at higher V, which is reminiscent of a tran

183 Endothelial cells are critical sensors of shear stress but the mechanisms by which they decode com

184 We discovered that high and prolonged shear stress caused sustained [Ca(2+)](i) elevation that

185 rate that the expression of this receptor is shear stress dependent and downregulated in patients rec

186 This process continues until the effective shear stress drops and dislocation activities stop.

187 genetic studies, we could recapitulate high shear stress effects on isolated human monocytes under h

188 the mechanisms by which they decode complex shear stress environments to regulate physiological and

189 d viable after filtration due to the minimal shear stress exerted over cells during the procedure, wh

190 s have the capacity to quantify and localize shear stress experienced by endothelial cells.

191 Here we show that shear stress favours mitochondrial biogenesis and metabo

192 xide from all other cells while enduring the shear stress imposed by navigating small vessels and sin

193 WIST1 and HOX family genes, are regulated by shear stress in arteries in adults.

194 red for the response of endothelial cells to shear stress in vitro and in vivo and regulates the site

195 lood components with artificial surfaces and shear stress inside extracorporeal membrane oxygenation

196 ural tube-paraxial mesoderm interfaces where shear stress is highest.

197 The application of shear stress is known to enhance tight junction formatio

198 Conversely, physiologically high shear stress is protective.

199 How integrin binding under shear stress mechanosignals a functional shift in iMo to

200 Shear stress on arteries produced by blood flow is impor

201 cell (PBMEC) culture to assess the impact of shear stress on barrier formation using the Kirkstall Qu

202 l cells, Piezo1 channel activation by either shear stress or a chemical agonist Yoda1 activated a dis

203 We first confirmed that either fluid shear stress or the Piezo1 agonist, Yoda1, led to an ele

204 molecular mechanosensors to directly detect shear stress profiles that will ultimately lead to ather

205 pment but also drives atherosclerosis in low shear stress regions of adult arteries.

206 we describe these studies, which reveal that shear stress regulates diverse processes and demonstrate

207 The application of shear stress resulted in a reorientation and enhancement

208 capsule with DMSO, ultrasound, or mechanical shear stress resulted in capsule alterations that affect

209 Shear stress stimulates lipophagy, contributing to the p

210 odilator activity, given its contribution to shear stress stimuli and diverse biochemical reactions w

211 tric oxide signalling through alterations in shear stress stimuli and haemoglobin scavenging of nitri

212 Statistical covariation for the shear stress stimulus did not alter FMD, indicating that

213 atation occurred in the face of an unaltered shear stress stimulus for vasodilatation and reduced res

214 ng blood generates a frictional force called shear stress that has major effects on vascular function

215 obes regulate cell adhesion strength at high shear stress through intricate molecular mechanisms incl

216 The resolution of high shear stress through TAVI reduces Mac-1 activation, cell

217 composites not only promotes the interfacial shear stress to a high level and thus results in signifi

218 nd (3) cultured endothelial cells exposed to shear stress to decrease CSE expression and treated with

219 under static conditions or exposed to fluid shear stress to decrease CSE expression; and (3) culture

220 an aortic endothelium or rVCAM-1 under fluid shear stress was assessed using a microfluidic-based art

221 n Combined analysis of lumen volume and wall shear stress was associated with enlargement of abdomina

222 Perfusion of TEBVs at a physiological shear stress with enzyme-modified low-density-lipoprotei

223 w patterns that exert low or low oscillatory shear stress, a mechanical environment that promotes vas

224 moted melanoma cell invasion, survival under shear stress, adhesion to endothelial cells under contin

225 stem behavior, such as advection regimes and shear stress, and derive estimates for relevant quantiti

226 ssure-induced wall stress, flow-induced wall shear stress, and exogenous sources of angiotensin II, w

227 arious mechanical stimuli including stretch, shear stress, and osmotic pressure.

228 We demonstrate that high shear stress, as present in patients with aortic valve s

229 In response to high shear stress, HUVECs and SC cells expressed more SEAP an

230 pal TM transducer of physiological levels of shear stress, with both shear and the Piezo1 agonist Yod

231 r highly controlled conditions, showing that shear stress-dependent calcium influx and monocyte adhes

232 studies included endothelial cell adhesion, shear stress-induced cell alignment, blood pressure meas

233 mplicated in high venous pressure- and fluid shear stress-induced vascular hyperpermeability in endot

234 for cross-fiber, and 0.039 +/- 0.011 kPa for shear stress.

235 iPSCs), to study their vulnerability to flow shear stress.

236 n fluorescent protein (GFP) and subjected to shear stress.

237 ral and material properties as a function of shear stress.

238 nction of the strength and duration of fluid shear stress.

239 ause they were grown in the absence of fluid shear stress.

240 of flow and produce nitric oxide under high shear stress.

241 ertical sides of the healing-gap due to high shear stress.

242 vival and viability during exposure to fluid shear stress.

243 canal (SC), theoretically increasing luminal shear stress.

244 n 30 min after exposure to arterial rates of shear stress.

245 dic measurements also highlight the key role shear-stress has in enabling this interaction.

246 vanced this field by integrating specialized shear-stress models with systems biology approaches, inc

247 hnique, the cells are perfused under defined shear stresses over a monolayer of endothelial cells (ex

248 (MC) with high specificity under a range of shear stresses.

249 f cellular deformation at moderate-to-higher shear stresses.

250 are subjected to in vivo like fluid flow and shear stresses.

251 ons of uniaxial compression tests and direct shear tests were presented for the same ballast types.

252 ning values consistent with both tensile and shear tests.

253 ion, splitting tensile, triaxial, and direct shear tests.

254 cal measurement results, NG depicted similar shear thinning behaviour to gelatine, within shear rates

255 results can be interpreted as an interfacial shear thinning of the polymers with an increasing relaxa

256 These bioinks are shear thinning, resist cell sedimentation, improve viabi

257 tress fluids, materials that exhibit extreme shear thinning.

258 nglement and DNA hybridization, resulting in shear-thinning and cyclic strain properties.

259 Also, shearing flow testing showed shear-thinning and thixotropic behaviors, which are shar

260 s with reduced storage moduli but retain the shear-thinning behavior and consistent mechanical recove

261 nonstationary condition, exhibits power-law, shear-thinning behavior and scales exponentially with sa

262 ortia by utilizing a temperature-responsive, shear-thinning hydrogel to compartmentalize organisms in

263 he addition of both terminal domains exhibit shear-thinning, a property which native spidroins also s

264 ents have been computed over a wide range of shear velocities V.

265 ghest rates of earthquakes and prominent low shear velocities, whereas the preceding history of dehyd

266 bducted oceanic crust shows a large negative shear velocity anomaly at the phase boundary between sti

267 ith different length scales except large low shear velocity provinces (LLSVPs).

268 estimates point at ~0.20 m/s as the critical shear velocity threshold causing soil C(org) erosion.

269 g factor was calculated as the ratio of zero-shear viscosities, each as obtained from the MD (in phys

270 critical 'Dirac fluid' is expected to have a shear viscosity close to a minimum bound(3,4), with an i

271 as reflected by an increased A-W interfacial shear viscosity of the adsorbed film upon defatting.

272 ies of the system by measuring the effective shear viscosity, finding that this increases as active f

273 Shear wave elastography (SWE) is a relatively new techni

274 , we investigate the potential of ultrasound shear wave elastography (SWE) to detect vulnerable carot

275 and share wave imaging, which include point shear wave elastography and 2D shear wave elastography.

276 Shear wave elastography assessments were performed using

277 to target the consistency of healthy cervix shear wave elastography measurements and examine the cha

278 include point shear wave elastography and 2D shear wave elastography.

279 Shear wave speed was also recorded from the MG muscle be

280 e maximum joint torque and with the relative shear wave speed, suggesting that variable gearing may e

281 e maximum joint torque and with the relative shear wave speed, suggesting that variable gearing may e

282 ciations with maximum joint torques and with shear wave speeds.

283 "transonic" velocities, bounded between the shear wave velocity of the softer material and a limitin

284 ted of multifrequency 3D-MRE (mf3D-MRE) with shear waves delivered at different frequencies to explor

285 lastography (OCE), which launches and tracks shear waves to estimate stiffness, provides an attractiv

286 s initiate as "subshear" cracks (slower than shear waves) that transition to developed slip pulses wh

287 microfluidics to control the application of shear, we generated fibres from single-protein condensat

288 sualized orientation with flow vector at any shear, which may be due to greater vorticity and thus in

289 that combines strain-controlled oscillatory shear with stress-controlled recovery tests.

290 rmation of silk fibrils is largely driven by shear, yet it is not known what factors control the path

291 cal earthquakes along the Eastern California Shear Zone (ECSZ) which started in 1872 and are associat

292 ith return flow below the Eastern California Shear Zone, leading to the extrusion of the Mojave block

293 tent explainable, given constraints on fault/shear-zone interaction and the build-up and release of s

294 nd is dependent on the geometry of the fault/shear-zone system.

295 egional tectonics through slip on underlying shear zones and fault planes have spatially smooth stres

296 fected by ductile deformation into localized shear zones deforming via diffusion creep, dissolution-p

297 duction and creep cavitation along localized shear zones enhanced fluid-carbonate interactions and fl

298 the rapid development of damage areas in the shear zones of Pine Island and Thwaites ice shelves.

299 triggers the development of damage in their shear zones, which results in further speedup, shearing,

300 ault sets that link adjacent or intersecting shear zones.