コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 netic analysis of paired specimens confirmed shedding of 2 distinct HSV-2 strains collected at differ
2 g of the mammalian Aurora B kinase, triggers shedding of a kinetochore protein, preventing microtubul
3 typic H5N1 virus was associated with reduced shedding of a pandemic H1N1 virus challenge, while vacci
4 how that genetic depletion of SUB2 abolishes shedding of a range of parasite proteins, identifying pr
5 ytes, resulting in significantly upregulated shedding of ADAM17 substrates, including EGF-family grow
6 d physicochemical modification of Ag NPs and shedding of Ag+, leading to an increased bioavailability
7 levels in all tissues and show virtually no shedding of all tested ADAM17 substrates, to clarify the
9 r of ADAM9, these results indicate increased shedding of angiotensin-converting enzyme in the alveola
10 and ADAM cleavage assays to demonstrate that shedding of at least 12 of these proteins are potentiall
12 hanism of immune escape involving tumor cell shedding of B7-H6, a ligand for the activating receptor
14 in the feed showed a progressive decline in shedding of bacteria, significantly lower immune respons
22 hanism studies showed that CgA inhibited the shedding of cancer cells in circulation from primary tum
26 nd in vivo results point to a P2X7-dependent shedding of CD62L (with high levels in the serum), which
28 processes involving cleavage, processing, or shedding of cell adhesion molecules, growth factors, cyt
31 rize a novel viral strategy to influence the shedding of cell-surface molecules involved in immune re
39 epredation in feedlots contributing to fecal shedding of ciprofloxacin-resistant E. coli, but a singl
41 ributes and ADT-sensitivity, and reduces the shedding of circulating tumor cells in vivo with signifi
45 ory signaling events by promoting ectodomain shedding of cytokine precursors and cytokine receptors.
47 ive cholestyramine therapy reduced the fecal shedding of daptomycin-resistant E. faecium by up to 80-
49 cantly reduced the expression of heparanase, shedding of DeltaHS, and loss of occludin as detected by
50 embrane metalloprotease mediating ectodomain shedding of diverse membrane proteins, was recently sugg
57 functional relevance of iRhom2 in regulating shedding of EGF receptor (EGFR) ligands is established b
58 gulates oligodendrogenesis by modulating the shedding of EGFR ligands TGFalpha and HB-EGF and, conseq
59 rowth factor receptor (EGFR) activity and on shedding of EGFR ligands; exposure to 12% CO2 without ad
61 ase inhibitor studies show that constitutive shedding of endogenous DDR1 in breast cancer HCC1806 cel
65 further induces activation of Rho kinase and shedding of endothelial microparticles carrying miR-503,
70 uction in oxygen coincides with an increased shedding of eukaryotic viruses in the oxycline, and a sh
71 rse astrophysical phenomena, for example the shedding of excess angular momentum from protostars by t
73 han Coronin 1C-reexpressing cells due to the shedding of extracellular vesicles (EVs) containing MT1-
75 ith PMA or N-ethyl-maleimide resulted in the shedding of FcgammaRIIIA/CD16A and CD62L, a specific sub
79 in host response to bacterial infection and shedding of foodborne pathogens, a systematic profiling
81 ors involves the synthesis and extracellular shedding of gangliosides, a class of biologically active
86 and ADAM17 can produce sgp130 by ectodomain shedding of gp130, even though this mechanism only accou
87 r was associated with macrothrombocytopenia, shedding of GPIbalpha, impaired platelet adhesion to von
88 tion of either of the ITAM receptors induces shedding of GPVI and proteolysis of the ITAM domain in F
91 al-regulated kinases (ERK1/2) pathway by the shedding of growth factors which triggers the formation
93 nation is achieved is poorly understood, but shedding of guidance cues by metalloproteinases is emerg
95 a showed decreased expression and ectodomain shedding of HB-EGF and reduced incidence of cancer devel
96 oned medium on the expression and ectodomain shedding of HB-EGF by TNFalpha-converting enzyme/a disin
98 mal models of sepsis or endotoxemia leads to shedding of heparan fragments from the endothelial glyco
99 y high glucose was associated with increased shedding of heparan sulfate (DeltaHS) and the tight junc
100 confirmed the superfusion results and caused shedding of heparan sulfate, pointing to disruption of t
105 symptomatic STIs, is associated with seminal shedding of HIV in men receiving ART, conferring a poten
107 es a potential mechanism for acquisition and shedding of HIV via chronic leukocyte recruitment to the
109 cantly reduced the number of days of vaginal shedding of HSV-2 DNA compared with that for mock-immuni
110 7 for prevention of genital disease, vaginal shedding of HSV-2 DNA, and latent infection of dorsal ro
111 imals had little effect on recurrent vaginal shedding of HSV-2 DNA, despite significantly reducing ge
112 r, 5/8 animals in each group had subclinical shedding of HSV-2 DNA, on 15/168 days for the gC2/gD2 gr
114 rrent genital lesions, and recurrent vaginal shedding of HSV-2 DNA; however, protection was incomplet
115 Pharmacological treatments revealed that shedding of hTfR1 by PC7 requires endocytosis into acidi
118 tion of ICOS/ICOSL results in ADAM10-induced shedding of ICOSL on B cells and moderate ICOS internali
119 pport a role for metalloproteinase-dependent shedding of IgLON family members in regulating neurite o
120 dentify that platelet-inflammasome-dependent shedding of IL-1beta and caspase-1-carrying platelet EVs
125 ion in this model, it is not ADAM17-mediated shedding of IL-6R within the pouch that orchestrates thi
127 spiratory viruses revealed that NS2 promotes shedding of infected epithelial cells, resulting in two
134 ve and inducible metalloproteinase-dependent shedding of integrin beta2 from mouse macrophages are de
135 es the ability of metalloproteinase-mediated shedding of integrin beta2 to promote macrophage efflux
139 toxicity and was able to selectively inhibit shedding of known ADAM10 substrates in several cell-base
140 phils showing signs of increased reactivity: shedding of l-selectin, CD11b upregulation, increased ox
145 l tract, which resulted in a delayed vaginal shedding of live organisms, accelerated the chlamydial s
147 significantly slowed down after 10 h due to shedding of LRP-1 from the cell surface and formation of
149 17) is a membrane-bound enzyme that mediates shedding of many membrane-bound molecules, thereby regul
151 eveloped a new assay to quantitatively track shedding of membrane proteins from the surface of EVs.
152 metalloprotease 10 (ADAM10) is required for shedding of membrane proteins such as EGF, betacellulin,
153 creases soluble RANKL by reducing ectodomain shedding of membrane RANKL through downregulation of met
154 y amyloid fibrils is caused by the molecular shedding of membrane-active oligomers in a process that
157 rm of CD154 (sCD154), which results from the shedding of membrane-bound CD154, plays a key role in th
158 ugh inhibition of invadopodia maturation and shedding of membrane-derived microvesicles, the two key
159 ey to this process is the protease-mediated "shedding" of membrane-tethered ligands, which then activ
160 ntify the proteolytic enzyme responsible for shedding of meprin A, we generated stable HEK cell lines
161 istate 13-acetate-, and ionomycin-stimulated shedding of meprin beta and meprin A in the medium of bo
166 ubicin and melphalan) selectively affect the shedding of MIC molecules that are sensitive to proteoly
169 Patients with sepsis also displayed reduced shedding of monocyte tumor necrosis factor receptors upo
170 thin the lipid bilayer, an event preceded by shedding of most of the substrate's ectodomain by alpha-
171 indings support a role for MT3-MMP-dependent shedding of NgR1 in regulating excitatory synapse develo
173 ses is attenuated, and they have an enhanced shedding of noninfectious particles and are incapable of
174 (human Y422) is shown to be associated with shedding of NUP62 from the nuclear pore complex (NPC) an
176 maged, and its degradation is accompanied by shedding of one or more glycocalyx components into the b
178 c strains from adhesion to NETs involved the shedding of outer membrane vesicles (OMVs) that outcompe
179 embly of the actin cytoskeleton, followed by shedding of plasma membrane microvesicles, disassembly a
182 This approach enabled us to discriminate the shedding of prions in saliva and the detection of prions
183 nt to CWD biology from our analyses: (i) the shedding of prions in saliva increases with time postino
184 f chronic wasting disease (CWD) results from shedding of prions produced at high titers in the periph
185 genicity through tissue factor upregulation, shedding of procoagulant MPs, endothelial nitric oxide s
188 in the CNS of HIV-infected people, increase shedding of PrP(c) from human astrocytes by increasing t
189 These results indicate that by promoting the shedding of PrP(C) in human neurons, ADAM10 activation p
193 Vaccinees exhibited significantly reduced shedding of RhCMV in saliva and urine following RhCMV ch
200 did not receive mOPV2, as assessed by faecal shedding of Sabin 2 by reverse transcriptase quantitativ
205 rical results predict the previously unknown shedding of satellite droplets during the destabilizatio
207 herapeutic anti-EGFR antibodies also inhibit shedding of sEGFR, thus implicating the cell surface pre
209 d yet ADAM17 is unable to support stimulated shedding of several of its substrates, including heparin
210 e we show that activity-dependent ectodomain shedding of signal regulatory protein-alpha (SIRPalpha)
211 samples from 37 participants, we found that shedding of sIL-6R from neutrophils was greater in carri
216 critical role in phagocytosis), resulting in shedding of soluble-Mer (sMER) and loss of MERTK functio
217 , is crucial for the rapid activation of the shedding of some, but not all substrates of ADAM17.
221 However, secreted MMP-7 participated in the shedding of Syndecan-4 from the surface of B-lymphocytes
222 of MMP-7 which in turn is important for the shedding of Syndecan-4 in response to infectious stimuli
226 ction is also critically dependent on normal shedding of terminally differentiated keratinocytes, a p
227 mic domain of ADAM17 show reduced stimulated shedding of the ADAM10 substrate betacellulin, whereas t
228 levated CO2 also inhibited stretch-activated shedding of the ADAM17 substrate TNFR1 from airway epith
229 tacellulin, whereas the ionomycin-stimulated shedding of the ADAM17 substrates CD62-L and TGFalpha is
231 regulating extracellular matrix turnover and shedding of the adipogenic regulator DLK1, but that in a
239 poietic cells, supported TACE maturation and shedding of the EGFR ligand TGF-alpha in Rhbdf2-deficien
240 evidence of a mechanism involving ectodomain shedding of the EGFR ligands amphiregulin (AREG) and TGF
241 dent manner, leading to increased ectodomain shedding of the epidermal growth factor (EGF) receptor (
243 It was reported that exercise promotes the shedding of the extracellular domain of Fndc5, generatin
245 elial-to-mesenchymal transition (EndoMT) and shedding of the glycocalyx are early changes of endothel
249 mechanisms, including but not limited to: 1) shedding of the HER2 extracellular domain, 2) steric hin
253 this article, we describe that an increased shedding of the NKG2D ligand MICA is observed postinfect
254 in and metalloproteinase) protease-dependent shedding of the Notch ligand Delta-like 1 (Dll1), leadin
255 her by increasing ADAM17-mediated ectodomain shedding of the Notch receptor or by modification of spe
258 ated platelets and endothelial cells induces shedding of the P-selectin ectodomain into the circulati
260 e I was activated through the acid-triggered shedding of the polymeric shell of the NCa, resulting in
265 s undesired premature drug release until the shedding of the shell, which accelerates the cleavage of
266 NMDA receptor activation rapidly triggers shedding of the signalling-competent NRG2 extracellular
267 cretase complex is preceded and regulated by shedding of the substrate's ectodomain by alpha- or beta
270 aluate the persistence, biodistribution, and shedding of the vector following subretinal delivery.
272 ion as cell surface receptors, or mainly via shedding of their secreted ectodomains, such as neurotro
276 susceptibility gene for ccRCC and ectodomain shedding of this molecule may be a predictive biomarker
279 protection of hepatocytes involves the rapid shedding of TNF receptor 1 to limit TNFalpha signaling.
280 ng TNF-converting enzyme-mediated ectodomain shedding of TNF type I receptor (TNFR1), the membrane-bo
281 TNF-alpha convertase (TACE), which controls shedding of TNF-alpha and its biological activity in viv
283 role for iRhom2 in promoting ADAM17-mediated shedding of TNFRs in hepatic stellate cells, which reduc
287 ng ALCAM in tumor-bearing mice revealed that shedding of tumor, but not host-derived ALCAM is elevate
288 betaFurKO cells show impaired cleavage or shedding of vacuolar-type ATPase (V-ATPase) subunits Ac4
293 t the utility of analyzing sewage to monitor shedding of viral pathogens and the high viral diversity