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1 d products that may be used by the host (eg, short-chain fatty acids).
2 is a G protein-coupled receptor activated by short chain fatty acids.
3 S to generate acetate and propionate as main short chain fatty acids.
4 ctional saturated long-chain fatty acids and short-chain fatty acids.
5 including anaerobic fermentation to generate short-chain fatty acids.
6 vation of fatty acid receptors for long- and short-chain fatty acids.
7 tors, two pathways that could be affected by short-chain fatty acids.
8 s, including 5-azacytidine, hydroxyurea, and short-chain fatty acids.
9 s was confirmed by the reduced production of short-chain fatty acids.
10 ng non-mannanolytic populations that produce short-chain fatty acids.
11 ta dysbiosis and increased the production of short-chain fatty acids.
12 sending one-carbon units into production of short-chain fatty acids.
13 acteroidetes, and marked reductions in cecal short-chain fatty acids.
14 high-fiber diet and supplementation with the short-chain fatty acid acetate on the gut microbiota and
15 e impact of a microbiota-derived metabolite, short-chain fatty acid acetate, on an acute mouse model
18 ntestinal regions by sensing lactate and the short-chain fatty acids acetate and butyrate and then al
21 41), are each predominantly activated by the short-chain fatty acids acetate, propionate, and butyrat
25 d long-chain fatty acids exacerbate, whereas short-chain fatty acids ameliorate, autoimmunity in the
28 a, a commensal bacterial genus that produces short chain fatty acids and endotoxins, each of which ma
30 bserved in media containing a combination of short chain fatty acids and glucose and surprisingly, in
31 G protein-coupled receptor that responds to short chain fatty acids and has generated interest as a
32 or 2 in which Gi-mediated signalling by both short chain fatty acids and synthetic agonists was maint
34 ch diverse environmental cues (e.g., certain short-chain fatty acids and bile acids) inhibit SPI-1 ex
35 and interleukin-1beta), rebalanced levels of short-chain fatty acids and bile acids, improved gut bar
36 ceramides, and an increased incorporation of short-chain fatty acids and dihydroxylated bases into in
37 at the microbiome, through the production of short-chain fatty acids and in particular, butyrate, is
41 one deacetylase (HDAC) inhibitors, including short-chain fatty acids and suberanilohydroxamic acid (S
42 nd redox potential through the production of short-chain fatty acids and that the bacteria adjacent t
43 iota-derived physiological modulators (e.g., short-chain fatty acids) and pathogenic mediators (e.g.,
44 olite pools (acylcarnitines, bile acids, and short-chain fatty acids), and levels of antibodies in ho
46 ble to identify dysregulation of bile acids, short-chain fatty acids, and cholesterol derivatives tha
47 egrading microbes, produced higher levels of short-chain fatty acids, and drove higher adiposity when
48 of evidence suggest that microbially derived short-chain fatty acids, and particularly butyrate, can
49 f trimethylamine and trimethylamine N-oxide, short-chain fatty acids, and secondary bile acids, that
50 nts of the digestion of lipids consisting of short chain fatty acids are higher than those of lipids
55 ission after FMT and had increased levels of short-chain fatty acid biosynthesis and secondary bile a
56 under low- or high-fat feeding, particularly short-chain fatty acids, but not hydrogen sulfide, direc
57 ipase showed the highest specificity towards short-chain fatty acids butanoic and hexanoic acids, the
58 phenylbutyrate (PBA) is a derivative of the short-chain fatty acid butyrate and is approved for trea
59 ation between an increase in the circulating short-chain fatty acid butyrate and pain improvement fol
61 ut neither AcAc nor the structurally related short-chain fatty acids butyrate and acetate, suppresses
62 ation for increased hepatic IR injury, fecal short-chain fatty acids butyrate and propionate levels w
64 erium in the human skin microbiome, produces short-chain fatty acids by glycerol fermentation that ca
66 acid (VPA), which, like NaB, belongs to the short-chain fatty acid class of HDAC inhibitors, fails t
67 ated amino acids and nicotinate and depleted short chain fatty acids compared to crude fecal control
73 cronutrient intake, stool diaries, and fecal short-chain fatty acid concentrations.Patients were rand
75 he gut microbiota ferment carbohydrates into short-chain fatty acids, convert dietary and endogenous
76 hnospiraceae impact their hosts by producing short-chain fatty acids, converting primary to secondary
77 odelling indicate that Rv2509 belongs to the short-chain fatty acid dehydrogenase/reductase (SDR) fam
79 -28 are required for the biosynthesis of the short-chain fatty acid-derived side chains of the dauer
80 tion pathways for corresponding alcohols and short-chain fatty acids, dissimilatory sulfur oxidation,
82 and acetogens may be a significant factor in short chain fatty acid formation in the colon contributi
84 uman acyl-ACP substrate and readily releases short chain fatty acids from full-length FASN during tur
85 disaccharides partially restored total fecal short-chain fatty acids from the level significantly rep
86 at a group of metabolic by-products, namely, short-chain fatty acids, from bacteria that cause period
89 uorobenzyl bromide derivatives of these very short chain fatty acids have high sensitivity of isotopo
90 icrobial and anti-inflammatory activities of short-chain fatty acids have been previously well charac
91 when cultured with butyric acid, a principal short-chain fatty acid in the fermentation metabolites o
92 uch uptake was correlated with appearance of short-chain fatty acids in basal side of the everted sac
94 s microbiota-liberated sugars, hormones, and short-chain fatty acids in regulating pathogenicity.
96 on of resistant starch leads to increases in short-chain fatty acids, including the clinically benefi
97 volved in the metabolism of carbohydrates to short-chain fatty acids, increases in colonic short-chai
98 ry activity exhibited chemical properties of short chain fatty acids known to be produced from C. acn
99 y in mice, in part through the production of short-chain fatty acids leading to Treg cell development
100 evealed no significant difference in gas and short chain fatty acid level among substrates evaluated.
101 e abundance of Bacteroidetes, elevated fecal short chain fatty acid levels, enrichment of genes assoc
102 Y-FL-pentanoic-acid staining revealed higher short chain fatty acids levels in the intestine of treat
103 hort-chain fatty acids, increases in colonic short-chain fatty acid levels, and alterations in the re
104 crobial organophosphate degradation produces short chain fatty acids like acetic acid, which induces
105 mary effect of HDAC inhibition by endogenous short-chain fatty acids like lactate is to promote gene
106 pendent beta-oxidation of microbiota-derived short-chain fatty acids limits oxygen availability in th
107 ed by gut microbes, increasing production of short chain fatty acids (mainly acetate and lactate) and
108 that supplementation of germ-free mice with short-chain fatty acids, major products of gut bacterial
109 beneficial to the host and demonstrates that short chain fatty acids may be useful to limit formation
110 The metabolites of colon microbiota, e.g. short-chain fatty acids, may influence the brain and beh
111 r 3 (FFA3, previously GPR41) is activated by short-chain fatty acids, mediates health effects of the
112 ociated with EAE susceptibility, implicating short-chain fatty acid metabolism as a key element conse
114 0.3 log(10) 16S rRNA gene copies per gram), short-chain fatty acids, microbiome, and ileitis severit
115 ncrease 1.3 +/- 0.5 vs 0.9 +/- 0.6), and the short-chain fatty acids (mumol/g) acetate (decrease 27.4
117 Here, we discuss microbial regulation of short-chain fatty acids, neurotransmitters, as-yet-uncha
118 chicken nutrition through the production of short-chain fatty acids, nitrogen recycling, and amino a
120 ncreases the interest to elucidate impact of short-chain fatty acids on metabolism, obesity, and the
121 ration of 3-indolepropionic acid, serotonin, short chain fatty acids or tauroursodeoxycholic acid sho
123 conferred by bacterial metabolites, such as short-chain fatty acids, or the modulation of immune res
126 t has esterase activity, with preference for short-chain fatty acids, particularly acetate, with high
127 imethylamine/trimethylamine N-oxide pathway, short-chain fatty acids pathway, and primary and seconda
128 Fatty Acid Receptor 2 is a GPCR activated by short chain fatty acids produced in high levels in the l
131 idium-histolyticum groups, and increased the short-chain fatty acids produced compared to the negativ
132 ring diarrhea are considered to be important short-chain fatty acid producers and may be important fo
133 detected and included reduced abundances of short-chain fatty acid-producing bacteria in Canadian HE
134 es identified a significant reduction in the short-chain fatty acid-producing taxonomies Akkermansia,
135 o differences in gut microbiota diversity or short chain fatty acid production across time or with di
139 Bifidobacterium animalis potentiates colonic short chain fatty acids production and decreases abundan
140 the therapeutic effects of metformin through short-chain fatty acid production, as well as for potent
142 these associations, typified by the role of short-chain fatty acids, products of fibre fermentation
144 A decrease in cecal pH and alterations in short chain fatty acid profiles occurred with consumptio
145 lactate, a slightly acidic pH, and specific short-chain fatty acid profiles, which are high in aceta
146 hat dietary fructose- and microbiota-derived short-chain fatty acids promote AckA-mediated acetic aci
147 o parallel pathways for the breakdown of the short chain fatty acid propionate in Caenorhabditis eleg
148 ng the activity of the endogenously produced short chain fatty acid propionate in Gi-mediated pathway
149 tive concentrations of the anti-inflammatory short-chain fatty acids propionate, acetate and butyrate
150 lycylsarcosine), lipid (oleoylethanolamine), short chain fatty acid (propionate) and major rat bile a
152 ylmethionine (SAM) cycle and breaks down the short-chain fatty acid propionic acid, preventing its to
153 colonic secondary bile acids, lower colonic short-chain fatty acid quantities and higher mucosal pro
157 opulation distinguished by expression of the short-chain fatty acid receptor free fatty acid receptor
158 Depletion of CD25(+) Tregs or absence of the short-chain fatty acid receptor GPR43 abolished this sur
160 erative colitis and sodium butyrate (NaB), a short chain fatty acid (SCFA) normally produced in the i
162 terial community, stool microRNA (miRNA) and short chain fatty acid (SCFA) signatures to correlate th
164 breadth of cellular responses engendered by short chain fatty acid (SCFA)-hexosamine hybrid molecule
165 acidifying the proximal colon and triggering short chain fatty acid (SCFA)-mediated intracellular aci
167 , plasma and muscle biochemistry, intestinal short chain fatty acids (SCFA), and liver glycogen of tr
169 Fermentation end products, in particular the short-chain fatty acid (SCFA) acetate, are believed to b
170 igated the effect of Propionic acid (PPA), a short-chain fatty acid (SCFA) and a product of dys-bioti
171 aturing Gradient Gel Electrophoresis (DGGE), short-chain fatty acid (SCFA) and ammonium analyses were
172 iched diet on gut microbiota composition and short-chain fatty acid (SCFA) concentrations in parallel
173 in cell culture by sodium butyrate (NaB), a short-chain fatty acid (SCFA) histone deacetylase (HDAC)
174 notyping, gut metagenomic sequence and fecal short-chain fatty acid (SCFA) levels were available(2),
175 P < 0.0001), stool frequency (P = 0.02), and short-chain fatty acid (SCFA) producer Lachnospira [fals
176 d comparative analyses of gut microbiota and short-chain fatty acid (SCFA) profiles across different
178 nockout mice studies implicate the mammalian short-chain fatty acid (SCFA) receptors, FFAR2 and FFAR3
182 s and diversity, depletion of anaerobes, and short-chain fatty acid (SCFA)-producing bacteria, and an
183 f carbohydrates (CHOs) and proteins produces short-chain fatty acids (SCFA) and a range of other meta
185 his study evaluated the properties of faecal short-chain fatty acids (SCFA) as diagnostic biomarkers
191 r without addition of gut metabolites called short-chain fatty acids ([SCFA)] produced during ferment
192 ed ligand selectivity and sensitivity to the short chain fatty acids (SCFAs) acetate and propionate.
193 (rutin) to identify phenolic metabolites and short chain fatty acids (SCFAs) and compare relative ant
195 the induction of T regulatory cells, and the short chain fatty acids (SCFAs) butyrate, propionate and
196 cytokines and an increase in IgA levels and short chain fatty acids (SCFAs) in both trachea and lung
197 pecially with no study of gut microbiota and short chain fatty acids (SCFAs) in nephrolithiasis.
198 nd lactobacilli, resulting in high levels of short chain fatty acids (SCFAs) in the cecal material an
199 ticle, we demonstrate that dietary fiber and short chain fatty acids (SCFAs) induced the expression o
200 g bacteria, which ferment dietary fiber into short chain fatty acids (SCFAs) known to be important fo
201 lacking intestinal commensals, which supply short chain fatty acids (SCFAs) such as acetate, also ex
206 3, GPR41) and 2 (FFA2, GPR43), for which the short-chain fatty acids (SCFAs) acetate and propionate a
207 tions in gastrointestinal microbiota-derived short-chain fatty acids (SCFAs) after allogeneic bone ma
210 if they can support methane bioconversion to short-chain fatty acids (SCFAs) and the associated micro
220 sobacterium nucleatum produce five different short-chain fatty acids (SCFAs) as metabolic by-products
221 okines (n = 29), fecal calprotectin, and the short-chain fatty acids (SCFAs) butyrate and propionate
223 weeks of treatment, PLPE increased levels of short-chain fatty acids (SCFAs) by enhancing abundance o
228 e investigated the role of microbial-derived short-chain fatty acids (SCFAs) including acetate, butyr
230 hods that simulate physiological conditions, short-chain fatty acids (SCFAs) production, and a detail
233 lating concentrations of the microbe-derived short-chain fatty acids (SCFAs) propionate and butyrate
234 ns, giving rise to the in situ production of short-chain fatty acids (SCFAs) such as propionic and bu
235 metabolic product of commensal bacteria are short-chain fatty acids (SCFAs) that derive from ferment
237 ch as depletion of gut bacteria that produce short-chain fatty acids (SCFAs) through gut fermentation
238 icroArray screen, we demonstrate that excess short-chain fatty acids (SCFAs) trigger replicative cell
239 t enrichment of selective bacteria producing short-chain fatty acids (SCFAs) was tested as a more tar
240 insulin and leptin were determined by ELISA; short-chain fatty acids (SCFAs) were measured in stool s
241 n be fermented by colon microbiota producing short-chain fatty acids (SCFAs) with the ability to prev
244 absorption, bifidobacteria, total bacteria, short-chain fatty acids (SCFAs), and fecal pH in women w
245 nt capacity, phenolic profile, production of short-chain fatty acids (SCFAs), and gut microbiota comm
246 y GPR43, a receptor for bacterially produced short-chain fatty acids (SCFAs), as a modulator of micro
247 naerobic metabolism, like butyrate and other short-chain fatty acids (SCFAs), induce regulatory T cel
248 ng's mice/wild-type (WT) littermates, mainly short-chain fatty acids (SCFAs), ketones, and alcohols,
252 plementation of antibiotic-treated mice with short-chain fatty acids (SCFAs), products of microbial m
253 and commensal microbes, such as vitamins and short-chain fatty acids (SCFAs), regulate Treg generatio
260 beneficial bacteria in the colon to produce short-chain fatty acids (SCFAs), which are proposed to h
261 fermentation of "indigestible" prebiotics to short-chain fatty acids (SCFAs), which in turn modulate
269 ds/pathways, with specific attention paid to short-chain fatty acids, secondary bile acids, trimethyl
271 sodium glucose tranporter-1 (SGLT-1) or the short chain fatty acid sensing receptor FFAR2 (GPR43), f
272 1) is a G-protein coupled receptor for which short-chain fatty acids serve as endogenous ligands.
276 nd 65 mug/g, respectively, which, along with short chain fatty acids such as butyric acid (13 mg/g) e
277 D, soluble fiber is the best way to generate short-chain fatty acids such as butyrate, which has anti
278 of germ-free mice with bacteria that produce short-chain fatty acids suppresses cFos expression in th
279 ed with schizophrenia include differences in short-chain fatty acids synthesis, tryptophan metabolism
280 driven with proteins, carbohydrates or other short-chain fatty acids, systems fed with acetic acid re
281 llulosic plant polysaccharides and releasing short chain fatty acids that are then metabolized by the
282 atty acid receptor 2 (FFAR2), a receptor for short-chain fatty acids that can affect the composition
285 biome supplies essential metabolites such as short-chain fatty acids to skeletal muscle mitochondria,
286 d, little is known about the contribution of short-chain fatty acids to the adipogenic differentiatio
287 rogenes for which the production of branched short-chain fatty acids was knocked out, we discovered t
288 6 and C18:3n3) from soya bean oil emulsions; short chain fatty acids were released faster than long c
289 s collected from five different time points; short-chain fatty acids were also analyzed in allergic o
291 ns were higher in African Americans, whereas short-chain fatty acids were higher in native Africans.
295 at plasma levels rather than fecal levels of short-chain fatty acids were relevant to inflammation an
296 enic glutathione complexes, arsenosugars and short chain fatty acids) were also evaluated to assess t
297 d GPR43, is a G-protein coupled receptor for short chain fatty acids which is involved in the mediati
298 r the direct conversion of lignocellulose to short-chain fatty acids, which included the funneling of
299 bundance and translocation of L. reuteri via short-chain fatty acids, which inhibited its growth.
300 tion of valproate (VPA), a widely prescribed short chain fatty acid with anticonvulsant and anticance