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1 kinetics of growth: linear, exponential and sigmoidal.
2 y than with 5-HT and its time course was not sigmoidal.
3 the oxygen binding curve becomes completely sigmoidal.
6 curves for wild-type tau fibrillization were sigmoidal and correlated well with measurements of total
10 this critical scan rate, the i-v response is sigmoidal as a result of hemispherical radial diffusion.
11 stant versus phosphodonor concentration were sigmoidal, as were PhoB binding isotherms for the phosph
12 f residues in the Ca(2+)-binding region were sigmoidal because of the contribution of chemical exchan
15 longitudinal diameter, adjusting the double sigmoidal behavior in response to changes in the time.
16 ypothesis that the mechanistic basis for the sigmoidal behavior is the same for both d-tyrosine activ
18 DNA concentrations compared to LoxP, but the sigmoidal behavior of the concentration dependence was m
24 ed five distinct stages characterized by two sigmoidal behaviors, showing the time-dependent transiti
27 toxins fail to form oligomers but still show sigmoidal binding to cholesterol-containing membranes.
29 erature dependence of steady active force is sigmoidal both in isometric and in shortening muscle.
30 4-, the velocity dependence on total Mg2+ is sigmoidal, but plateaus at high concentrations of free M
31 ents recovered by the control chimera have a sigmoidal Ca(2+) fluorescence (DeltaF/F) versus voltage
35 les and all NaCl-containing LDL samples, the sigmoidal changes in the absorbance units vs. temperatur
38 with Ca(II), Sr(II), and Ba(II) were highly sigmoidal, characterized by Hill coefficients of 2.3-6.5
40 obtained in an ethanol matrix demonstrate a sigmoidal concentration response over the physiologicall
42 pendence of the phosphorescence intensity is sigmoidal, consistent with cooperative actin filament bi
44 ty of the enzyme: dGTPase activity displayed sigmoidal (cooperative) behavior without DNA but hyperbo
45 reproduce the force/velocity characteristic sigmoidal correlation, while also reproducing the hand-o
46 est are sampled at a fixed time to produce a sigmoidal current-potential curve akin to a pseudo stead
47 curvature induced by endophilin and observe sigmoidal curvature/composition coupling isotherms that
52 on of the reduction potential and presents a sigmoidal curve that fits a quasireversible model and is
54 relaxation was closely fitted by a Boltzmann sigmoidal curve which allowed us to estimate the mean ME
55 vs. urine osmolality (OsmU) were fitted to a sigmoidal curve, and EC50 was determined by non-linear r
56 orded at different time scales into a unique sigmoidal curve, which clearly highlights kinetic compli
57 the HX reaction as a function of pH gives a sigmoidal curve, which reaches the maximal rate constant
58 ghted distribution of conformers describes a sigmoidal curve, with a transition midpoint near 1.5 kca
66 ffusion and transformed these data sets into sigmoidal curves characterizing the phase transition of
68 Folding was cooperative, as evidenced by the sigmoidal curves in solvent denaturation experiments.
69 peak-shaped CV and the plateau current in a sigmoidal CV, provides a simple means for calculating th
71 eets at a TOD (FTIR) of 72.4 degrees C and a sigmoidal decrease in IgY activity at TOD (ELISA) of 67.
73 d Delta21, a 50-ms depolarization produced a sigmoidal DeltaF/F versus voltage curve with a lower tha
75 ed (deuterated) water density region, with a sigmoidal density profile at the hydrophobic silane-wate
76 irion infectivity follows gp120 density as a sigmoidal dependence and reaches an apparent plateau.
77 cycle suppression by DNA damage, revealing a sigmoidal dependence of cell cycle on excess DNA damage.
78 performed under special conditions yielded a sigmoidal dependence of fiber tension on temperature--a
79 nt Kd values of 0.05 and 2.3 muM, based on a sigmoidal dependence of heme spin state on Nile Red conc
81 tration data than the Hill model, predicts a sigmoidal dependence of key parameters with calcium conc
83 By contrast, amylin fibrillogenesis has a sigmoidal dependence on heparin fragment length, with an
84 tic analysis for the double mutant reveals a sigmoidal dependence on homocysteine that is not observe
88 h respect to the filament axis had a roughly sigmoidal dependence on temperature in relaxing conditio
89 ve behavior: (i) the ATPase activity shows a sigmoidal dependence on the ATP concentration; (ii) ATPg
90 were found transported cooperatively with a sigmoidal dependence on the Cd2+ concentration (n = 1.4)
92 min produced similar results but shifted the sigmoidal dissociation curves to lower urea concentratio
93 subunit dissociation were evaluated from the sigmoidal dissociation data by assuming a single transit
94 in urea for 10 min at room temperature, the sigmoidal dissociation transitions were centered at 3.7,
96 e, LDL colocalized with proteoglycans with a sigmoidal dose dependence (inflection point, approximate
97 limitation, we developed and implemented the Sigmoidal Dose Response Search (SDRS) algorithm, a grid
98 taCr (p < .001) and ARF (p < .001) exhibited sigmoidal dose-dependent associations to lowest hematocr
99 The ability of quantification is shown by a sigmoidal dose-response curve fitting to analyze IL-6 pr
101 say was completed in less than 3 min and the sigmoidal dose-response curve spanned an antibody concen
102 tion of RNase H by these metal ions followed sigmoidal dose-response curves suggesting cooperative me
105 the cascade without feedback showed a steep (sigmoidal) dose-response and a wide, nearly bimodal yEGF
107 for Emax; P = .18 for quadratic; P = .21 for sigmoidal Emax 1; P = .39 for linear; and P = .52 for si
109 ng techniques (linear, Emax, 2 variations of sigmoidal Emax, and quadratic) was used to evaluate dive
110 so shown to target deoxyguanosine and showed sigmoidal enzyme kinetics (K0.5(deoxyguanosine) = 302 +/
113 th associated with coagulation diameter in a sigmoidal fashion (ex vivo, R(2) = 0.78; in vivo, R(2) =
114 hrough the bacterial membrane increased in a sigmoidal fashion as the AMP binding increased in time,
119 cal reaction in a ball mill exhibits unusual sigmoidal feedback kinetics that differ dramatically fro
122 the other single-loop chimeras, recovered a sigmoidal fluorescence-voltage curve indicative of skele
125 ng transient cyclic voltammogram (CV) with a sigmoidal forward wave followed by a peak-shaped reverse
126 lular calcium, maintained the characteristic sigmoidal frequency-intensity relationship and generated
127 (20 femtomoles, 1 mL) is estimated from the sigmoidal function best fitting (R(2) = 0.989) IAW exper
128 combined with data from previous studies, a sigmoidal function describes the overall trend throughou
133 lity distributions were parametrized using a sigmoidal function to determine TVFR0.5 (the temperature
136 racellular acidification response asymptotic sigmoidal functions and concentration-response behavior
138 , potentiation can be described by a pair of sigmoidal functions matched to input/output curves; (2)
140 non-exponential models: spatial 3d model and sigmoidal growth, relevant for early- and late stages of
141 ubstrate concentrations were best fit to the sigmoidal Hill equation, with a K(0.5) of 19.4 +/- 1.3 m
142 at although growth kinetics are likely to be sigmoidal in most cases, natural selection will restrict
143 the metal-ion dependence of DNA cleavage was sigmoidal in nature, and rates and levels of DNA cleavag
144 FTIR)) of 69.5 degrees C, concomitant with a sigmoidal increase in intermolecular (denatured) beta-sh
145 rownian hydrodynamics simulations, we find a sigmoidal increase of the enzymatic rate as a function o
148 by mercury poisoning, temperature-dependent sigmoidal kinetic curves, and dynamic light scattering.
149 CsgA polymerizes into an amyloid fiber in a sigmoidal kinetic fashion with a distinct lag, growth, a
151 uch nonlinear networks (NLN) readily lead to sigmoidal kinetic profiles as a function of the relative
153 aintains glucose homeostasis by displaying a sigmoidal kinetic response to increasing blood glucose l
154 s in modulation from substrate inhibition to sigmoidal kinetics (k(cat) = 1.7 +/- 0.3 s(-1), K(m) = 1
155 t if two structures are assumed to grow with sigmoidal kinetics (logistic and Gompertz) the resulting
158 rial strain alone degraded phenanthrene with sigmoidal kinetics but could not degrade alkanes or the
160 ther ACATs, EutT catalyzes the reaction with sigmoidal kinetics indicative of positive cooperativity
163 hermophilus tyrosyl-tRNA synthetase displays sigmoidal kinetics similar to those observed for activat
164 ith soluble diC8 PI(4,5)P(2) as a substrate, sigmoidal kinetics were observed, suggesting the presenc
165 Intriguingly, the inactivation exhibits sigmoidal kinetics with a Hill coefficient of 2.5 and an
166 xhibited hyperbolic kinetics, BAM2 exhibited sigmoidal kinetics with a Hill coefficient of over 3.
167 In vivo phosphorylated Cyt c shows enhanced sigmoidal kinetics with COX, and half-maximal turnover i
168 D-tyrosine, the activation reaction displays sigmoidal kinetics with respect to ATP concentration und
170 fers caffeoyl and 4-coumaroyl CoAs, exhibits sigmoidal kinetics with these substrates, and is substra
171 ow Si(OH)(4) concentrations, uptake followed sigmoidal kinetics, indicating regulation by an alloster
175 ron transport activity of CcO decreases in a sigmoidal manner during the first transition and this de
177 (a) also varied with C6PS concentration in a sigmoidal manner, whereas amidolytic activity of unlabel
179 alpha-helicity and do not show a cooperative sigmoidal melt with temperature, indicating that these m
181 tions, a plot of Vmax versus free Co2+ shows sigmoidal metal activation of MetAP1D, both with and wit
187 e receptor cells is thought to obey a static sigmoidal nonlinearity, which might be expected to produ
189 ge in the substrate-velocity response from a sigmoidal one seen with the native enzyme (Hill coeffici
190 betaN changes the nitrocefin kinetics into a sigmoidal one, suggested that PAbetaN inhibited the effl
193 e-response curve of split luciferase shows a sigmoidal pattern which indicates cooperativity in oligo
194 formation by the synthetic complex follows a sigmoidal pattern; following a quiescent induction perio
196 his equilibrium could be responsible for the sigmoidal pH dependence of the recovery of the dark-adap
198 n the exponential transfer functions and the sigmoidal pseudotransducer functions obtained in the lit
199 of syn-2 in the presence of CuCl(2) showed a sigmoidal quenching curve indicating cooperative recogni
200 rm face area, a face-space coding model with sigmoidal ramp tuning provided a better account of the d
201 ucose concentrations, thereby generating the sigmoidal rate dependence that defines kinetic cooperati
204 Hb deviates from second-order kinetics, and sigmoidal reaction progress is determined by a balance b
205 reactivation of equilibrium-unfolded mAAT is sigmoidal, reactivation of the short term unfolded prote
206 rs with a time constant of 91 ms whereas the sigmoidal recovery of triggering probability lags behind
209 hmark to evidence conformist transmission: a sigmoidal relation between individuals' probability to c
211 nder ecologically plausible conditions, this sigmoidal relation can also be detected without equippin
213 40 My to identify a well-defined and clearly sigmoidal relationship between atmospheric CO(2) and sea
218 Our analyses identify a strong nonlinear sigmoidal relationship between minimum temperature and B
219 surface concentrations, however, there was a sigmoidal relationship between the initial velocity and
222 le both pERK and egr1 mRNA show a saturating sigmoidal relationship to the concentration of GnRH expo
223 addition, the probability of severing has a sigmoidal relationship to the crossover dwell time, indi
224 ction, and the transport activity displays a sigmoidal relationship with the concentration of these l
225 ty amplification for competing ligands; both sigmoidal response and affinity amplification exhibit a
226 selenide phase, as manifested by a strongly sigmoidal response in optical spectroscopy and electron
231 nd velocity scales, qualitative pulse shape, sigmoidal response to stimulation amplitude (an 'all-or-
232 d the NBD-Cys or NBD-Hcy adducts generates a sigmoidal response with a dynamic range of 3 orders of m
233 ow-scan cyclic voltammetry (LSCV) revealed a sigmoidal response with a midpoint potential of -0.17 V
237 cromolar concentration range follow apparent sigmoidal sequential first-order kinetics, with rate con
239 c response of the bipolar cell has a similar sigmoidal shape and limiting current; however, the respo
240 t versus potential curve dependence showed a sigmoidal shape characteristic of mediated enzyme cataly
242 substrate potential features the retraceable sigmoidal shape of a quasi-steady-state voltammogram alt
243 ve P(50) values, coupled with the absence of sigmoidal shape of the O(2) equilibrium curves, was cons
246 was primarily valued according to a striking sigmoidal shape; its rate of change consistently present
247 rays are represented by two major regimes: a sigmoidal shaped i-v response for arrays acting as indiv
248 M KCl on each of the micro NEEs resulted in sigmoidal-shaped voltammograms which were reproducible a
250 te provides an intuitive explanation for the sigmoidal shifts in levels of phosphorylated substrate.
252 on system parameters that are necessary for sigmoidal signal-response relationships and define key p
255 eratures (or urea concentrations) and lack a sigmoidal signature characteristic of cooperative unfold
256 kinase is a monomeric enzyme that displays a sigmoidal steady-state kinetic response toward increasin
257 t initially appears as a twisted and writhed sigmoidal structure with a temperature as high as 10 MK,
258 AnsA is positively cooperative, displaying a sigmoidal substrate dependence curve with an [S](0.5) of
259 fts the reaction kinetics from hyperbolic to sigmoidal such that COX is fully or strongly inhibited u
261 ontent similar to WT and shows a cooperative sigmoidal temperature melt but with a decreased stabilit
262 ase "gated" reaction kinetics and a striking sigmoidal temperature profile that has led to a model of
263 sure of the sample (history dependence), and sigmoidal temporal behavior of the moisture-induced degr
264 s obtained with DCP-UO22+ from hyperbolic to sigmoidal, the latter characterized by Hill coefficients
267 THEMATICS measures deviation from typical, sigmoidal titration behavior to identify functionally im
268 anges in the presence of urea show curved or sigmoidal titration curves suggestive of direct urea bin
269 e of the DeltaF/F versus voltage curve, from sigmoidal to bell-shaped, with a maximum at approximatel
272 8A11-Cy5 and DCP-UO22+ species changed from sigmoidal to hyperbolic at high concentrations of protei
273 follow different curve shapes, ranging from sigmoidal to hyperbolic, according to the relative impor
275 tion study of compound 12c revealed both the sigmoidal topology of the polyyn-diyl bridge and the fin
276 damage is characterized by a lag phase and a sigmoidal transition, which matches the kinetic profile
277 determined from reversible and well-defined sigmoidal transitions revealed two distinct phases refle
278 a tail-to-tail dimer, showing monomer-dimer sigmoidal transitions, or as a head-to-tail noncentrosym
279 iacetyl, acetoin, and 2-butanone) followed a sigmoidal trend described by the modified Gompertz model
282 PAT to the binding of ATP was observed to be sigmoidal under fixed PhP concentrations, but substrate
283 ded as judged by CD and NMR, and all exhibit sigmoidal urea and thermally induced unfolding transitio
285 monolayer is confirmed by the appearance of sigmoidal voltammetric profile, characteristic behavior
287 ifera, both the stem and petiole had similar sigmoidal vulnerability curves but differed in pressure
288 t globular proteins exhibit a characteristic sigmoidal water adsorption isotherm at ambient condition
293 and the reciprocal absolute temperature was sigmoidal with half-maximal tension at 9.5 degrees C.
294 The ROI-biodegradability relationship was sigmoidal with higher biodegradability associated with P
295 eakly basic drug (quinine; pK(a) = 7.95) was sigmoidal with respect to -dF/M(w) values, with a profil
296 n versus reciprocal absolute temperature was sigmoidal, with a half-maximal tension at 10-12 degrees
298 dium activation of gemcitabine transport was sigmoidal, with a K0.5 of 8.5+/-0.3 mM for Na+ and a Hil
299 The pH dependence of this interaction is sigmoidal, with an apparent pK(a) for binding close to 5