ライフサイエンスコーパス: signal amplification

1 tic machinery catalyzing a click reaction (= signal amplification).

2 binding motifs to enable robust fluorescent signal amplification.

3 s serve as signal molecular nanocarriers for signal amplification.

4 ker by exploiting movement-triggered cascade signal amplification.

5 assemblies and gold nanoparticles (GNPs) for signal amplification.

6 p38(MAPK) to MK2 is characterized by strong signal amplification.

7 latent HIV reservoirs from patients without signal amplification.

8 h Au nanoparticles/graphene-chitosan for the signal amplification.

9 to hydration changes as may occur in visual signal amplification.

10 m), QD-SABER provides an additional 7.6-fold signal amplification.

11 ay reduce functional perturbation and enable signal amplification.

12 nitiated enzymatic polymerization (SIEP) for signal amplification.

13 t achieved by cocaine aptasensors relying on signal amplification.

14 e effectively, which subsequently results in signal amplification.

15 e, thereby activating the enzyme to initiate signal amplification.

16 ps are necessary for protein recognition and signal amplification.

17 ions, is sufficient to create high-frequency signal amplification.

18 ells-1 (TREM-1) is critical for inflammatory signal amplification.

19 with hybridization chain reaction (HCR) for signal amplification.

20 ent of any enzyme or nanomaterial labels for signal amplification.

21 results using enzymes or nanomaterials-based signal amplification.

22 rs to achieve functional readouts and robust signal amplification.

23 icant time delay or significant noise during signal amplification.

24 ndonuclease-assisted isothermal fluorescence signal amplification.

25 d secondary antibody solution and subsequent signal amplification.

26 gnostic tool for both linear and exponential signal amplification.

27 increment of Rct thus obtaining significant signal amplification.

28 cascade that yielded upward of 600,000-fold signal amplification.

29 and specific assay utilizing liposome-based signal amplification.

30 ld nanoparticle (CNT-AuNP) nanoclusters, for signal amplification.

31 mitochondrial defects drove the inflammasome signal amplification.

32 unclear why ORNs use an anionic current for signal amplification.

33 This transformation requires signal amplification.

34 tional Tr1 and Tr2, resulting in exponential signal amplification.

35 with dual gold nanoparticle (AuNP)-assisted signal amplification.

36 ins, it is unclear whether scaffolds promote signal amplification.

37 eroxidase-conjugated antibodies and tyramide signal amplification.

38 e release of activated JNK3 was critical for signal amplification.

39 sexta's sensitization occurs through central signal amplification.

40 sents lower signal spread ~0.08 x and higher signal amplification ~1.4 x , compared with conventional

41 we have combined two approaches for optical signal amplification: (1) a computational approach based

42 iotin groups were attached to promote strong signal amplification after binding to the target HIV RNA

43 ication of the target molecules or molecular signal amplification after target recognition.

44 atom transfer radical polymerization (ATRP) signal amplification and "Click Chemistry".

45 a two-layer cascade that yielded 7,000-fold signal amplification and a two-stage, four-layer cascade

46 Furthermore, strategies for signal amplification and also generation of reusable ele

47 y, the developed sensor showed a substantial signal amplification and consequently improved sensitivi

48 nism and plays important roles in chemotaxis signal amplification and coordination of multiple motors

49 multaneously achieving approximately 20-fold signal amplification and diffraction-limited spatial res

50 pathways might employ similar mechanisms for signal amplification and dispersion.

51 of p-LAT and p-SLP nanoclusters driving TCR signal amplification and diversification.

52 own remarkable impact both for anchoring the signal amplification and generate plasmonic resonant cou

53 They have the advantage of signal amplification and highly specific recognition.

54 nanocomposites enable higher sensitivity by signal amplification and introduce several novel transdu

55 ter kinetochore proteins promotes checkpoint signal amplification and lateral attachment, whereas the

56 agnostic systems for low cost improvement in signal amplification and limit of detection.

57 (poly-HRP, 400 HRPs) labels to provide large signal amplification and limits of detection in the sub-

58 oscopes, decrowds biomolecules in support of signal amplification and multiplexed readout chemistries

59 in electrodes and associated electronics for signal amplification and multiplexed readout.

60 a latent source of fluoride is reported for signal amplification and optical detection of fluoride.

61 ng strategy offers two important advantages, signal amplification and particular applicability in poi

62 sing the measurement speed, parallelization, signal amplification and preconcentration.

63 poly-L-lactide nanoparticles (PLLA NPs) for signal amplification and PSA detection.

64 y antigen-antibody interactions for enhanced signal amplification and selectivity.

65 scuss the importance of ROS in regulation of signal amplification and specificity in guard cells.

66 e quantitative relationship between the SERS signal amplification and the coloration degree within a

67 Lumi4-Tb complex is compatible with tyramide signal amplification and, unlike conventional organic dy

68 tion and fast magnetic separation, AgNPs for signal amplification, and an electrochemical stripping v

69 ould be related to conformational selection, signaling amplification, and probe dependence.

70 efficient FRET with >20% quantum yield and a signal amplification (antenna effect) of 25.

71 is paper, we demonstrate an enzyme-catalyzed signal amplification approach based on the controlled bi

72 Therefore, the hematin-based signal amplification approach has great potential in cli

73 In this work, we presented a novel signal amplification approach to construct an electroche

74 The combination of the two signal amplification approaches enables a ~1000x increas

75 target amplification or protein-enzyme based signal amplification are highly relevant, yet still plag

76 In our approach, protein recognition and signal amplification are modulated by a simple dual-func

77 acceptor (1) as a latent source of thiol for signal amplification, as well as optical detection of th

78 We design and implement a multiplexed signal amplification assay in which gel-bound enzymes tu

79 itative allele-specific real-time target and signal amplification assays on independent plasma-extrac

80 ase-related changes, as well as the inherent signal amplification associated with antigen-stimulated

81 As such, given the most likely low signal amplification at the pigment-to-transducin/phosph

82 Here we present tyramide signal amplification based method of multiple marker imm

83 and simulations we compared the outcomes of signal amplification based on either [Formula: see text]

84 he specific carbohydrate recognition and the signal amplification based on the gold-promoted reductio

85 The signal amplification because of redox cycling makes it p

86 dback circuits may have evolved not only for signal amplification but also for robustly generating bi

87 e amplitudes of several degrees, and suggest signal amplification by a complex interplay of ecologica

88 KK4/7-JNK3 cascade, as a model to understand signal amplification by a scaffold protein.

89 g of specific DNA targets and the subsequent signal amplification by a secondary DNA probe linked to

90 regulatory mode explains the paradox of cAMP signal amplification by accelerated PDE-mediated cAMP tu

91 tes cannot be achieved directly but requires signal amplification by catalysts, macromolecules, metal

92 Herein, based on dual signal amplification by CeO(2)@Ir nanorods (Ce@IrNRs) an

93 Here we report immunostaining with signal amplification by exchange reaction (Immuno-SABER)

94 ul technologies is reported, quantum dot and signal amplification by exchange reaction (QD-SABER), fo

95 Here we introduce signal amplification by exchange reaction (SABER), which

96 sed MSI method that combines the strength of signal amplification by immuno-enzymatic reactions with

97 ties such as strong adsorption of molecules, signal amplification by optical, high carrier mobility,

98 s, fragmentation of the 16s rRNA and further signal amplification by QDs were found to be the main pa

99 parahydrogen-induced polarization (PHIP) and signal amplification by reversible exchange (SABRE) at h

100 Here, we communicate how signal amplification by reversible exchange (SABRE) can

101 Signal amplification by reversible exchange (SABRE) is a

102 Signal amplification by reversible exchange (SABRE) is a

103 Signal amplification by reversible exchange (SABRE) is a

104 Signal amplification by reversible exchange (SABRE) of a

105 We use the signal amplification by reversible exchange (SABRE) tech

106 (1)H NMR signal amplification by reversible exchange (SABRE) was

107 The hyperpolarization of heteronuclei via signal amplification by reversible exchange (SABRE) was

108 3) C hyperpolarization of (13) C-acetate via signal amplification by reversible exchange (SABRE).

109 the p-H(2)-based hyperpolarization technique signal amplification by reversible exchange (SABRE).

110 nidazole is demonstrated using SABRE-SHEATH (Signal Amplification by Reversible Exchange in SHield En

111 ize the low-cost parahydrogen-based approach signal amplification by reversible exchange with studies

112 tinamide (vitamin B(3) amide) by conducting "signal amplification by reversible exchange" (SABRE) at

113 can be circularized and subjected to massive signal amplification by rolling circle amplification, le

114 data suggest a "conveyor belt" mechanism for signal amplification by scaffold proteins.

115 ultrasensitive sensory systems, the 10-fold signal amplification by the GC receptor is surprisingly

116 (BCCs) rely on Hedgehog (HH) pathway growth signal amplification by the microtubule-based organelle,

117 We show that LPHN-CHDC biochip with signal amplification capability could selectively and se

118 The proposed strategy renders the signal amplification capacities of TPrA and combines LAM

119 This study describes a novel isothermal signal amplification cascade called EzyAmp (enzymatic si

120 The signal amplification chamber contained two bead types ca

121 m water resonance, with more than 1000 times signal amplification compared to the direct NMR detectio

122 (18)F-fluoride signal amplification derived from microcalcifications wa

123 e quantitatively determined by measuring the signal amplification during FRET.

124 Heo et al. (2015) uncover a new mechanism of signal amplification during mitophagy through cooperativ

125 a recent report by others that the olfactory-signal amplification effected by the Ca(2+)-activated Cl

126 The transistor signal amplification efficiency is 38.2 siemens per ampe

127 The signal amplification efficiency of LPHN-CHDC is demonstr

128 tivation and reveal that multiple sources of signal amplification exist within the Ras-ERK module of

129 The textbook notion of signal amplification-few enzyme molecules process many m

130 tes as a radio frequency receiver performing signal amplification, filtering and downconversion mixin

131 in situ hybridization coupled with tyramide signal amplification (FISH-TSA), that this gene is locat

132 and cycle to produce exponential fluorescent signal amplification for miRNA detection.

133 ethod could be rationally evaluated, and the signal amplification for PQQ detection down to the picom

134 hole-mount tissues), as well as simultaneous signal amplification for ten different proteins using st

135 is a great challenge and require substantial signal amplification for the accurate and precise quanti

136 en, the efficiency of the Ag-FON surfaces in signal amplification for the detection of low ochratoxin

137 the gold nanoparticles were used as cascade signal amplification for the detection of target DNA.

138 on can be regarded as a polymerization-based signal amplification for the sensing of hemoglobin, as t

139 ious functions ranging from DNA computing to signal amplifications for biosensing.

140 sfer by ruthenium (Ru) complex and intrinsic signal amplification from GO(x) label, this method could

141 to 100 ng/mL-compared with the group without signal amplification (from 1 ng/mL to 100 ng/mL).

142 ent with a low threshold of activation, high signal amplification gain, and slow kinetics of inactiva

143 r model (SABRE) that includes parameters for Signal Amplification (gamma), Binding affinity (K(d)), R

144 ong power consumption, fabrication cost, and signal amplification has been a long-standing issue for

145 which is suitable for single-tube isothermal signal amplification, has increased sensitivity of plain

146 The HCVcAg assays with signal amplification have high sensitivity, high specifi

147 Together with signal amplification, HCR can serve as a confirmation of

148 nefits of this signaling strategy, including signal amplification, host evolutionary advantage, and m

149 as a reagent provides two opportunities for signal amplification: (i) the replication of phage insid

150 ng-induced conversion (RT-QuIC) and tyramide signal amplification immunohistochemistry (TSA-IHC).

151 We further demonstrated that signal amplification improves MERFISH performance when f

152 Signal amplification in biological systems is achieved b

153 ctivation and leads to direction sensing and signal amplification in cAMP gradients.

154 ually the same Kd, suggesting a mechanism of signal amplification in DCs requiring further study.

155 We demonstrate 5- to 180-fold signal amplification in diverse samples (cultured cells,

156 ) is one of the most common enzymes used for signal amplification in ELISA.

157 A new approach to signal amplification in fluorescence-based assays for se

158 (LSPR)-coupled fluorescence enhancement for signal amplification in molecular beacon detection.

159 These insights reveal the mechanism of signal amplification in NAIP-NLRC4 inflammasomes.

160 on pattern of endogenous DUX4, its method of signal amplification in the unique shared cytoplasm of t

161 od, as well as preferential accumulation and signal amplification in tumours.

162 ed a new strategy for attaining higher-order signal amplification, in which a target sequence templat

163 expectations arising from considerations of signal amplification, inhibitory interactions between re

164 The signal amplification is based on Pt-Au bimetal NPs posse

165 the combined capillary and image processing signal amplification is capable of measuring weak fluore

166 rotrench dual-electrode sensor with feedback signal amplification is demonstrated to give well-define

167 The principle of control signal amplification is found in all actuation systems,

168 Signal amplification is presumably obtained from the fac

169 and build interkinase connections that allow signal amplification, it is not yet clear why many syste

170 c pain, evidence suggests a common thread of signal amplification, leading to the unifying term 'ampl

171 find use for various research topics such as signal amplification, light-emitting new materials, and

172 phorylation of autophagy receptors creates a signal amplification loop operating in selective autopha

173 iRNA deregulations often establish a vicious signal-amplification loop in lymphoma associated with ad

174 Serial signal integration rather than signal amplification makes multi-step signal transductio

175 Catalysis-based signal amplification makes optical assays highly sensiti

176 etween Dishevelleds, which may function as a signal amplification mechanism in filopodia where PCP si

177 A new signal amplification mechanism without the need of a red

178 ary antibodies (which already has a built-in signal amplification mechanism), QD-SABER provides an ad

179 is is a simple, cost-effective, and feasible signal amplification method based on the organic compoun

180 developed in this work could be a promising signal amplification method for the sensitive and select

181 this work, we applied the nanocrystal-based signal amplification method to tetra(4-carboxyphenyl)por

182 Using this enzyme-free and isothermal signal amplification method, we were able to detect targ

183 d IgG, antibodies using an immunogold-silver signal amplification method.

184 NAs based on a miRNA-detection-selective SPR signal amplification method.

185 etection often requires the use of labels or signal amplification methodologies, resulting in both di

186 Various signal amplification methods can overcome the limitation

187 ty were obtained using highly novel chemical signal amplification methods demonstrating a standard de

188 t can be partially overcome by sophisticated signal amplification methods.

189 resent in all electronic devices, and enable signal amplification, modulation, and relay.

190 Thus any signal amplification must occur downstream of TCR trigge

191 als have facilitated achievement of enhanced signal amplification needed for the construction of ultr

192 Application of NEase assisted signal amplification (NESA) has been discussed for diagn

193 role that ubiquitination plays in promoting signal amplification, novel protein interactions, and pr

194 The level of signal amplification obtained from templated reactions i

195 e introduce a novel approach to AST based on signal amplification of bacterial surfaces that enables

196 on of HER2 can be attributed to the multiple signal amplification of MB during its accumulation to th

197 ve transposable elements (TEs) is ensured by signal amplification of the initial small RNA trigger, w

198 alytical sensing as a result of the inherent signal amplification of the resistive pulse method.

199 This occurs by environmental signal amplification or inhibition through developmental

200 pe output dynamics in distinct ways, such as signal amplification or overshoot minimization.

201 ectly to enzyme labels like HRP that provide signal amplification or with nanoparticles functionalize

202 d electrode (PDNA/ZnO/Pt-Pd/FTO) served as a signal amplification platform for the detection of the t

203 an electrochemical method based on liposomal signal amplification platform is proposed for simple, PC

204 ting as both a glycan recognition unit and a signal amplification probe.

205 Moreover, the dual-signal amplification process can be completed one-step i

206 izes a novel biotin-labeled polymer-mediated signal amplification process combined with targeting rRN

207 h the enzyme-tagged streptavidin to initiate signal amplification process.

208 werful strategy employed in enzyme-catalyzed signal amplification process.

209 on the inside of a vesicle, which leads to a signal-amplification process analogous to the biological

210 els without the use of catalytic enzymes and signal amplification processes.

211 ne aptamer-based sensors that do not rely on signal amplification, producing an apparent K(d) of 27 +

212 Thus, the signal amplification properties of liposomes can be adju

213 0 nM for Pb(2+)) and selectivity without any signal amplification, rapid detection (within 13 min per

214 The key signal amplification reaction for the checkpoint is the

215 andwich immunoassay in the upper paper and a signal amplification reaction in the lower paper.

216 ification, amenability to be interfaced with signal amplification schemes, and inherent biocompatibil

217 We demonstrate how it can lead to efficient signal amplification schemes, including stochastic reson

218 st in the design of chemical logic gates and signal amplification schemes.

219 confusion as to the underlying mechanism of signal amplification seen in PET-positive, CT-negative i

220 -radical polymerization reactions to provide signal amplification so that molecular recognition event

221 ection sensitivity of pico-molar without any signal amplification step and a dynamic range of at leas

222 ISA) without the need for an enzyme-mediated signal amplification step.

223 otocol without the use of a complex assay or signal amplification step.

224 noparticles only after DNA hybridization and signal amplification steps effectively avoids steric hin

225 an be combined with diverse pretreatment and signal amplification steps to query complex samples.

226 kers, followed by mRNA labeling and multiple signal amplification steps.

227 advances in DNA base biosensors with various signal amplification strategies for detection of cancer

228 Actually, label-based signal amplification strategies of SPR platforms includi

229 roach to this issue is development of stable signal amplification strategies.

230 ly on target amplification or any additional signal amplification strategies.

231 nsors, such as DNA nano-machines and various signal amplification strategies.

232 g the telomerase and EXO III based two-round signal amplification strategy as the signal enhancement

233 In this work, we employed a signal amplification strategy based on carbon nanotube-b

234 wich-based immunoreaction couple with double signal amplification strategy based on catalytic enlarge

235 Based on a new signal amplification strategy by the toehold strand disp

236 both CNTs and AuNPs, represents a promising signal amplification strategy for achieving a sensitive

237 An enzyme-free signal amplification strategy for colorimetric detection

238 A novel signal amplification strategy for ultrasensitive multipl

239 was the first report on the integration of a signal amplification strategy into a microfluidic paper-

240 The proposed signal amplification strategy is more straightforward an

241 Based on a novel signal amplification strategy the carbon dots (CDs) func

242 ctive surface platform and a novel CNT-based signal amplification strategy to develop a lable-free im

243 tracted from chilli fruits, based on a novel signal amplification strategy using enzyme technology.

244 A multiple signal amplification strategy was designed for an ultras

245 In the present study, a triple signal amplification strategy was developed for ultrasen

246 Based on this designed two-round signal amplification strategy, both the sensing range an

247 Au) for LPS detection without any additional signal amplification strategy.

248 duplex-specific nuclease (DSN)-assisted dual signal amplification strategy.

249 This can be achieved by a viable signal amplification strategy.

250 gned capture, detector probes, and a QD SPRi signal amplification strategy.

251 Use of a dual hot-spot signal-amplification strategy based on AuNP-AgNP heterod

252 ew also discusses various strategies used in signal amplification such as nanomaterials, redox mediat

253 Under optimized conditions, the exponential signal amplification system shows a good linear range of

254 s well as for the development of sensing and signal amplification systems.

255 ated to gold nanoparticles (AuNPs) used as a signal amplification tag.

256 tibodies (TiP-Cd(2+)-MalphaPA antibodies) as signal amplification tags.

257 could be easily developed to be a universal signal amplification technique and applied to detection

258 This dual signal amplification technique was achieved by employing

259 the enzyme-assisted target recycling (EATR) signal amplification technique.

260 rther show that click-ExM is compatible with signal-amplification techniques and two-color imaging.

261 catalysis, in particular, is integral to the signal amplification that allows for biological informat

262 The signal amplification that improves the analytical perfor

263 plification cascade called EzyAmp (enzymatic signal amplification) that is being developed for detect

264 ce the enzymatic action of TDP1 is the only "signal amplification" the increase in fluorescence may e

265 To add specificity and signal amplification, the bound LPS molecules were furth

266 t Ca(2+) influx triggers adaptation but also signal amplification, the latter by opening a Ca(2+)-act

267 Compared to enzyme-based signal amplifications, the assay can detect the target R

268 the optimal processing or export of AIP for signal amplification through AgrC/A and induction of vir

269 and its interaction with Lys leds to a great signal amplification through measuring changes in differ

270 nated protein-protein interactions imparting signal amplification to different networks for physiolog

271 receptor-effector coupling efficiency links signal amplification to signal sensitization between rec

272 advent of nicking endonucleases (NEases) as signal amplification tools have greatly enhanced the det

273 N(-1) at a bias of 1.0 V) without using any signal amplification tools.

274 We used tyramide signal amplification (TSA) and label-free mass spectrome

275 on, whereas FISH detection involves tyramide signal amplification (TSA).

276 fied gold nanoparticles (AuNPs) were used as signal amplification unit because the DNA strands in thi

277 n this work, we report a simple strategy for signal amplification using appropriately functionalized

278 Here, the possibility of label-free signal amplification using end-point polymerase chain re

279 munoassay was implemented for TGF-beta1 with signal amplification using V-Phe-SWCNT(-HRP)-anti-TGF co

280 Ir84a ORNs, PPK25 mediates Ca(2+)-dependent signal amplification via an intracellular calmodulin-bin

281 ined to be about 10 Hz, potentially allowing signal amplification via chemical exchange saturation tr

282 no-SABER), which achieves highly multiplexed signal amplification via DNA-barcoded antibodies and ort

283 stem loop primer that facilitates downstream signal amplification via enzymatic turnover and improves

284 In addition, signal amplification was accomplished by using a commerc

285 Signal amplification was achieved through catalysis, by

286 Signal amplification was achieved through dilution of ph

287 High intrinsic signal amplification was achieved through the combined u

288 Signal amplification was achieved through the use of gra

289 Signal amplification was acquired by employing high-curv

290 enzyme-assisted strand cycle for exponential signal amplification was designed.

291 immunosensing system with voltage-controlled signal amplification was used to detect Shigella in stoo

292 Using highly sensitive tyramide signal amplification, we determined that LANA localizes

293 cial surfaces for potential interactions and signal amplification when activation is initiated.

294 are modified (methylated) and the other for signal amplification when they are unmodified (unmethyla

295 This leads to Notch1 signal amplification, which can promote melanoma tumor g

296 ent non-PCR detection methods rely on linear signal amplification, which hinders the detection of sma

297 Combining ATRP signal amplification with "Click Chemistry", the optimiz

298 Enzyme-catalyzed signal amplification with an antibody-enzyme conjugate i

299 t allows coupling of the restriction cascade signal amplification with any DNA target of interest.

300 SABER offers independently programmable signal amplification without in situ enzymatic reactions