ライフサイエンスコーパス: signal sequence

1 system that previously did not act as a Pdu signal sequence.

2 nucleosomes 5' to each Jkappa recombination signal sequence.

3 possibly preventing premature release of the signal sequence.

4 etory protein and was cleaved as part of the signal sequence.

5 gages translating RNCs exposing a functional signal sequence.

6 pecific activity and contain a predicted Sec signal sequence.

7 pable of secreting a related CDC without its signal sequence.

8 cysteine-rich protein harboring a predicted signal sequence.

9 ents, indicating that the CTD functions as a signal sequence.

10 e nucleus, suggesting it is a nuclear export signal sequence.

11 a blunt end on the neighboring recombination signal sequence.

12 ported that exemplifies SRP54 binding of any signal sequence.

13 protein that lacks an endoplasmic reticulum signal sequence.

14 tive Sec61 channel that has been opened by a signal sequence.

15 crimination between bacterial and eukaryotic signal sequences.

16 conserved twin-arginine (RR) motif in their signal sequences.

17 proteins are synthesized with amino-terminal signal sequences.

18 nslocation of small proteins with N-terminal signal sequences.

19 on of precursors with marginally hydrophobic signal sequences.

20 d to any segment of the nascent chain except signal sequences.

21 able to directly and tightly bind to nascent signal sequences.

22 human diseases are connected with defects in signal sequences.

23 s of Vbeta14, Dbeta, and Jbeta recombination signal sequences.

24 ociated conformational changes in downstream signal sequences.

25 epeats (TIRs) resembling V(D)J recombination signal sequences.

26 t structural cue of variability of exchanged signal sequences, 10.5-mo-olds gaze-followed an entity's

27 together with HMGB1 bind to a recombination signal sequence (12RSS or 23RSS) to form the signal comp

28 ments flanked by complementary recombination signal sequences (12RSS and 23RSS)(6).

29 als a small precursor containing a secretion signal sequence, a 14 amino acid N-terminal propeptide,

30 meric structure comprising an amino-terminal signal sequence, a phytocyanin-like domain, an AGP-like

31 f a membrane glycoprotein to the cytosol via signal sequence ablation resulted in rapid processing of

32 RP, while positive charges fine-tune the SRP-signal sequence affinity and targeting to the translocon

33 he N terminus of mature TDH comprises a T3SS signal sequence, allowing it to be loaded into the T3SS.

34 ar domain and the signal leader peptide (LP) signal sequence (amino acids 1 to 22) and contained the

35 This protein contains an N-terminal signal sequence, an extracellular region, a transmembran

36 containing six repeat domains, an N-terminal signal sequence and a C-terminal anchoring motif (LPXTG)

37 PFA0210c is unusual in that it contains a signal sequence and a PEXEL export motif that together m

38 possesses a functional nuclear localization signal sequence and binds to chromatin.

39 rved lipobox motif within the prolipoprotein signal sequence and catalyzes the addition of diacylglyc

40 location and severity of the mutation in the signal sequence and correlates with inhibition of SRP in

41 rame to the L. monocytogenes listeriolysin O signal sequence and driven by the hly promoter (h30) or

42 By choosing an appropriate ER signal sequence and expression vector, this simple techn

43 ne proteins, such as CadC or RodZ, lacking a signal sequence and having a far-downstream hydrophobic

44 requires substrates to present an accessible signal sequence and is not initiated simply by substrate

45 Signal sequence and prodomain cleavage in the ER and Gol

46 By exchanging signal sequence and protein domains of similar size betw

47 In the endoplasmic reticulum (ER), signal sequence and signal anchors (SAs) facilitate tran

48 d to SecA targeting to SecYEG via the native signal sequence and stable insertion of the downstream 2

49 esent evidence that TssM harbors an atypical signal sequence and that its secretion is mediated by th

50 40 amino acids of gp120 were replaced by the signal sequence and the first 27 amino acids of the matu

51 C-dependent manner with both the hydrophobic signal sequence and the membrane anchor sequence promoti

52 dicted to encode an Igbeta protein lacking a signal sequence and thus unable to serve normal B cell r

53 ERdj4 was reported to retain its signal sequence and to be resistant to mild detergent ex

54 c61 protein-conducting channel by regulating signal sequence and transmembrane helix insertion in a s

55 roduced by the full system I, with a cleaved signal sequence and two covalent bonds to haem.

56 within intron 13 identified intronic poly(A) signal sequences and adjacent cis-elements as the princi

57 The isoforms have identical 66 base pair signal sequences and different numbers of subsequent ice

58 ay compensate for their poorer recombination signal sequences and for being distant from CTCF sites.

59 proteins possessing N-terminal ER targeting signal sequences and multiple hydrophobic segments, sugg

60 on channel to discriminate between authentic signal sequences and the less hydrophobic amino acid seg

61 is known about the interactions between MCP signal sequences and the protein shells of different MCP

62 ind to ribosome-nascent chain complexes with signal sequences and undergo a series of distinct confor

63 e (SRP), which recognizes ribosomes carrying signal sequences and, through interactions with the SRP

64 inner membrane translocon and, thus, have a signal sequence, and (iv) transmembrane alpha-helix pred

65 on from codon 1, possesses an amino-terminal signal sequence, and is a type one integral membrane pro

66 microsporidian hexokinases gained secretion signal sequences, and in a functional assay these were s

67 g translocation, the hydrophobic segments of signal sequences, and probably bilayer-spanning domains

68 Nuclear localization and lack of an export signal sequence are consistent with the view of IL-33 as

69 Proteins with highly hydrophobic signal sequences are first recognized by the signal reco

70 Thus, signal sequences are functionally nonequivalent in vivo,

71 How signal sequences are recognized is poorly understood, pa

72 in flux into the ER, where mRNAs that encode signal sequences are released from the ER to the cytosol

73 e protein have only a mild effect on the SRP-signal sequence association.

74 uced protein sequence of BYS1 has a putative signal sequence at its N terminus, opening the possibili

75 lation extends the nascent chain, moving the signal sequence away from SRP on the ribosomal surface.

76 ion of a simian virus (SV40) polyadenylation signal sequence between the LAT promoter and miR-H6 sequ

77 ecognition particle (SRP), information about signal sequence binding in the SRP's M domain must be ef

78 op is the first structural element to detect signal sequence binding; this information is relayed to

79 universally conserved "fingerloop" lines the signal sequence-binding groove of SRP; the precise role

80 ribosomal protein L24 lead to a constricted signal sequence-binding pocket possibly preventing prema

81 ind this conserved ORE, namely recombination signal sequence-binding protein Jkappa (RBPJ), coiled-co

82 , TM3, TM7, and TM8 in Sec61p) to expose the signal sequence-binding site.

83 ubstrate proteins bearing mutant, suboptimal signal sequences both in vitro and in vivo.

84 s an ordered SRP RNA and SRP M domain with a signal sequence-bound.

85 Similar to CLICs, SspA lacks a signal sequence but contains an omega GST fold.

86 antii 3937 rhs genes do not encode secretion signal sequences but are linked to hemolysin-coregulated

87 t the position adjacent to the recombination signal sequence, but rather is trimmed back three or mor

88 P30 is predicted to have an N-terminal signal sequence, but the presence of such a motif has no

89 se displacement of SRP from the ribosome and signal sequence by SecYEG, and elongation of the nascent

90 Substrates with less hydrophobic signal sequences bypass the SRP and are moved through th

91 We termed the PilA signaling sequence CIP for "cell-cycle initiating pilin"

92 The propilin is processed by signal sequence cleavage and covalent linkage of the N a

93 early maturation events for EDEM1 including signal sequence cleavage and glycosylation were analyzed

94 Together, these results demonstrated that signal sequence cleavage functionally regulated the asso

95 Signal sequence cleavage of EDEM1 was found to be a slow

96 peptide motif immediately C-terminal to the signal sequence cleavage position that regulates its tra

97 Signal sequence cleavage produced a soluble form of EDEM

98 RET-based assay using a peptide based on the signal sequence cleavage region of the secreted LasB ela

99 sites of nontryptic cleavage consistent with signal sequence cleavage, as well as C-terminal motifs t

100 secreted into the milieu subsequent to their signal sequence cleavage.

101 Moreover, the Pdu-localized signal sequences competed with native Pdu targeting sequ

102 ins of Ms1704 and Ms1712, not the N-terminal signal sequences, confer SecA2-dependent export.

103 is mediated by the presence of an N-terminal signal sequence containing a highly conserved twin-argin

104 kpoints are flanked by cryptic recombination signal sequences (cRSSs) and frequently have non-templat

105 Importantly, blocking this signalling sequence decreased the dilatation to skeletal

106 azide resistance (Azi(r)) and suppression of signal sequence defects (PrlD).

107 of the identified cargos possess a recycling signal sequence defined as OX[L/M/V], where O is F/Y/W.

108 ubiquitin ligase, and define the degradation signal sequence (degron) of HOXB4 required for CUL4-medi

109 be explored, we show that the Pdu-localized signal sequences described herein allow control over the

110 he endoplasmic reticulum-targeting prolactin signal sequence did not affect StAR association with the

111 Cues in the signal sequence direct the membrane translocation of sur

112 An N-terminal signal sequence directs the secretion of the major curli

113 ox A at both 12- and 23-spacer recombination signal sequences, disrupting stable binding of HMGB1.

114 Although signal sequences do not have homology, they have similar

115 y analyzing in transgenic mice the impact of signal sequence efficiency for mammalian prion protein (

116 Remarkably, improving signal sequence efficiency mitigated these effects of ag

117 highest affinity shortly after a functional signal sequence emerges from the ribosome.

118 y displaces NAC from RNCs; however, when the signal sequence emerges further, trimeric NAC.RNC.SRP co

119 e signal recognition particle (SRP) binds to signal sequences emerging from the ribosomal tunnel and

120 Signal sequence-encoding mRNAs undergo translation-depen

121 whose cleavable N-terminal cpSecA-dependent signal sequence engages the thylakoid membrane cotransla

122 ted by HLA-DQ2/8 DC: an HLA-DQ8trans-binding signal-sequence epitope previously identified as CD8 T-c

123 multiple splice forms, polymorphisms, intron signal, sequencing errors, alignment errors, annotation

124 The C-terminal signal sequence facilitates secretion of SidJ into host

125 When mutant signal sequences fail to bind to the signal recognition

126 t all of them contain a nuclear localization signal sequence flanking to the K1 segment and a novel c

127 n, binding of RAG1 and RAG2 to recombination signal sequences flanking antigen receptor V, D, and J g

128 a glycosylphosphatidylinositol (GPI) anchor signal sequence followed by GPI-phospholipase D digestio

129 Thus, when signal sequence follows SA-I immediately, the interactio

130 IC) are non-classical ion channels lacking a signal sequence for membrane targeting.

131 ACBP lacks a signal sequence for secretion through the endoplasmic re

132 at has two known functions: E3 serves as the signal sequence for translocation of the E3-E2-6K-E1 pol

133 The hydrophobic core of the signal sequence forms a helix that sits in a groove outs

134 RP effectively distinguish RNCs displaying a signal sequence from those that are not?

135 xplained by the demonstration that efficient signal sequence function precludes generation of a cytos

136 P66 was also expressed using the PelB signal sequence fused to maltose binding protein.

137 tial rearrangements from V(D)J recombination signal sequence fusions.

138 defined by retaining its GPI anchor peptide signal sequence (GPI-PSS).

139 ylphosphatidyl-inositol (GPI) anchor peptide signal sequence (GPI-PSS).

140 1 influenza virus in which the hemagglutinin signal sequence has been suppressed (S-FLU), when admini

141 at accessible and inaccessible recombination signal sequences has been lacking.

142 The positive charges in the signal sequence helped it to override the function of si

143 y charged or helix-breaking mutations in the signal sequence hydrophobic core prevent synthesis of th

144 fusions provided the initial support for the signal sequence hypothesis in prokaryotes and allowed fo

145 A hydrophobic segment downstream of the signal sequence impeded complete translocation of Pink1

146 n IFITM3, the conserved YXXtheta endocytosis signal sequence in the N-terminal domain of duck IFITM3

147 minal region of Vfr comprising the secretion signal sequence in trans restored a wild-type speB expre

148 Here we propose that variability of signal sequences in a turn-taking exchange provides an i

149 contingent turn-taking exchange of variable signal sequences induce 10.5-mo-old preverbal infants to

150 D1 receptor-expressing neurons and that this signaling sequence induced aversion through GABA-mediate

151 ut not KFMDeltaSS, which lacks the secretion signal sequence, induced re-sensitization of cells to an

152 Channel opening allows signal sequence insertion into a gap between the N- and

153 site-specific photocrosslinking to study SRP-signal sequence interactions.

154 p into the SecY channel with the hydrophobic signal sequence intercalated into the open lateral gate.

155 city threshold for functional insertion of a signal sequence into the Sec61 complex, thereby allowing

156 ing it for the passage of low-hydrophobicity signal sequences into the lipid phase, without displacin

157 TCDD+Endosulfan elicit a complex signaling sequence involving reticulum endoplasmic desta

158 characterization established that the ERdj4 signal sequence is cleaved to yield a soluble protein.

159 having a CTCF site near their recombination signal sequence is critical, suggesting that being posit

160 cinity of the ribosome exit tunnel where the signal sequence is extending beyond its hydrophobic bind

161 Interestingly, only the internal signal sequence is necessary for complementation of the

162 We show that an exogenously added signal sequence is not sufficient for Sec-dependent Ply

163 If signal sequence is placed far enough from SA-I, then it

164 Thus, the hydrophobic core of the signal sequence is primarily responsible for its recogni

165 de complex in the dimer, which reveals how a signal sequence is recognized by SRP54.

166 The signal sequence is then cleaved by signal peptidase II (

167 trix protein p17 (p17), although devoid of a signal sequence, is released by infected cells and detec

168 the N terminus of SrtC2, which contains the signal sequence, is required for proper protein transloc

169 cision circles, genomic intron recombination signal sequence k-deleting element coding joint, genomic

170 n TCR excision circles, intron recombination signal sequence k-deleting element signal joints on Igka

171 In this study, we report that another signal sequence lacking cytoplasmic protein, superoxide

172 Nutrient deprivation triggers the release of signal-sequence-lacking Acb1 and the antioxidant superox

173 alleles, with suboptimal Vbeta recombination signal sequences limiting synchronous rearrangements and

174 As Nmnat2 is not predicted to contain a signal sequence, lipid-binding domain, or transmembrane

175 /Icm substrate being secreted by an internal signal sequence, many other substrates may be exported i

176 ly points of infection, whereas the internal signal sequence mediates secretion at later time points.

177 uss a tentative model of how a twin arginine signal sequence might be accommodated in the Tat translo

178 onal process, characterized by recombination signal sequence motifs near breakpoints, incorporation o

179 Severity of signal sequence mutations correlated with increased prox

180 ion particle, which recognizes a hydrophobic signal sequence near the protein N terminus.

181 3 rule is intrinsic neither to recombination signal sequences nor to the catalytic process of recombi

182 for the first time that mutations within the signal sequence of gK blocked cell surface expression of

183 point to a key role for the 8mer within the signal sequence of gK in HSV-1-induced pathogenicity.

184 Mutation in the signal sequence of gK in MgK virus blocked cell surface

185 that the 8mer peptide (ITAYGLVL) within the signal sequence of gK promotes cell surface expression o

186 cule Qa-1 bound to peptides derived from the signal sequence of Hsp60 (Hsp60sp) contribute to self/no

187 of naturally occurring mutations within the signal sequence of insulin.

188 highly dependent on their structure and the signal sequence of targeted proteins and can be narrowed

189 The signal sequence of TEM-1 tolerated InDels more than the

190 -MKKFRW that is predominantly present in the signal sequence of the bacterial protein MgrB, a highly

191 viruses with or without mutations within the signal sequences of gK.

192 To investigate the role of the signal sequences of herpes simplex virus 1 (HSV-1) gK on

193 at are based upon the hydrophobic N-terminal signal sequences of human apolipoproteins.

194 looked cryptic nonamers in the recombination signal sequences of human IGHD genes and demonstrate tha

195 particle (SRP) cotranslationally recognizes signal sequences of secretory proteins and targets ribos

196 Signal recognition particle (SRP) recognizes signal sequences of secretory proteins and targets them

197 ated into the middle of wild-type or mutated signal sequences of the secretory protein preprolactin b

198 ly involved in binding of positively charged signaling sequences of cargo proteins.

199 pies of ESAT-6 plus CFP-10 fused to the OmpC signal sequence (OmpC(SS)-E2C) and amino acids 44 to 338

200 terial inner membrane through recognition of signal sequences on cargo proteins.

201 ing either a C-terminal wild-type GPI anchor signal sequence or a nonraft transmembrane sequence cont

202 at charged residues at the N-terminus of the signal sequence or in the early part of the mature prote

203 Although it has no obvious signal sequence or transmembrane-spanning domains, CtpA

204 omains (e.g., a membrane surface), by adding signal sequences or fusing the sensors to specific prote

205 hain length and the exposure of a functional signal sequence outside the ribosome.

206 xisomal protein import, the variant receptor-signal sequence pair forms the basis of a system in whic

207 activity related to the start/stop activity signaling sequence parsing, we found neurons displaying

208 TDE and E. coli expressing MOSP with a PelB signal sequence (PelB-MOSP), MOSP(C) is OM-embedded and

209 d from those processed by B lymphocytes; PPI signal-sequence peptides were eluted from HLA-DR4 and -D

210 , with the PEXEL motif repositioned near the signal sequence, prevented PMV cleavage.

211 ted only at regions containing recombination signal sequences, RAG2 binds at thousands of sites in th

212 rotein S4, Y linked; solute carrier 1A5; and signal sequence receptor 1) were found in the syncytiotr

213 inefficient due to the small time window for signal sequence recognition by the signal recognition pa

214 a balance between translocation activity and signal sequence recognition fidelity.

215 sec61 alleles, which reduce the fidelity of signal sequence recognition.

216 rs before the first transmembrane helix, the signal sequence recognized by the signal recognition par

217 Mutations in the C-terminal signal sequence region of cdE2 affected E2 protein trans

218 gly, only secretion mediated by the internal signal sequence requires IcmS/IcmW.

219 ing gene segments and flanking recombination signal sequences (RS), with the two coding ends and two

220 mediated looping can influence recombination signal sequence (RSS) accessibility by regulating enhanc

221 ment, directly adjacent to the recombination signal sequence (RSS), placing the RSS in a position acc

222 b of the V(H)-leader exon, and recombination signal sequence (RSS)-associated sites characteristicall

223 aled distinct bending modes at recombination signal sequence (RSS)-conserved regions before nicking a

224 cutting DNA at the borders of recombination signal sequences (RSS) and their neighboring gene segmen

225 ated genomic rearrangements at recombination signal sequences (RSS) in human lymphocytes.

226 ess by binding to two types of recombination signal sequences (RSS), 12RSS and 23RSS, and cleaving at

227 ine gene segment is flanked by recombination signal sequences (RSs).

228 ins, which recognize conserved recombination signal sequences (RSSs) adjoining variable (V), diversit

229 essible chromatin structure at recombination signal sequences (RSSs) but how this accessibility is ge

230 ecombinase binding and cutting recombination signal sequences (RSSs) composed of conserved heptamer a

231 2 recombinase (RAG) recognizes recombination signal sequences (RSSs) containing a heptamer, a spacer

232 t relies on the recognition of recombination signal sequences (RSSs) flanking the individual elements

233 how that the poor qualities of recombination signal sequences (RSSs) flanking Vbeta gene segments sup

234 Inefficient Vbeta/VH recombination signal sequences (RSSs) have been hypothesized to cause

235 the RAG1 and RAG2 proteins to recombination signal sequences (RSSs) that consist of conserved heptam

236 RAG)1 and RAG2 bind and cleave recombination signal sequences (RSSs), aided by the ubiquitous DNA-bin

237 ) containing two complementary recombination signal sequences (RSSs), the 12RSS and 23RSS, which diff

238 ation involve breaks at single recombination signal sequences (RSSs).

239 at matched pairs of bona fide recombination signal sequences (RSSs).

240 gets, and predicted quality of recombination signal sequences (RSSs).

241 ng AgR loci and locally at the recombination signal sequences (RSSs).

242 ving DNA adjacent to conserved recombination signal sequences (RSSs).

243 n suppression of the A/PR/8/34 hemagglutinin signal sequence (S-FLU) that can infect cells and expres

244 for structure and topology prediction, (iii) signal sequence score because most TMBBs are secreted th

245 d residues in the hydrophobic portion of the signal sequence severely affect SRP binding.

246 Finally, overexpression of the Vfr secretion signal sequence significantly decreased speB transcript

247 fied mature Bacillus cereus SleB without its signal sequence (SleB(M)) and the SleB C-terminal cataly

248 cal E-box within the Dbeta2 12-recombination signal sequence spacer prior to Tcrb recombination.

249 A distinct peptide in the Vfr secretion signal sequence specifically bound to recombinant RopB.

250 Nonetheless, when E3 is replaced with an ER signal sequence, spikes do not form and infectious parti

251 8 of antigen 85A (Ag85A(294)) flanked by the signal sequence (SS) and C-terminal peptide (CT) of beta

252 aged the ER immediately after or even before signal sequence (SS) emergence, a class of Sec66-depende

253 Specifically, an outer membrane (OM) type II signal sequence (SS) fused to the heterologous mCherry f

254 he cglE and cglF genes instead encode type I signal sequences, suggesting that nonlipoproteins are al

255 Tgl, the cglC and cglD genes encode type II signal sequences, suggesting that they are also lipoprot

256 via a large nuclear complex that recognizes signal sequences surrounding a poly(A) site on mRNA prec

257 Hydrophobic signal sequences target secretory polypeptides to a prot

258 Mislocalized proteins bearing a signal sequence that did not successfully translocate th

259 protein GspB has a 90-residue amino-terminal signal sequence that is essential for transport by SecA2

260 been proposed to contain a carboxy-terminal signal sequence that is necessary and sufficient for exp

261 tract and did not appear to have a predicted signal sequence that might suggest the possibility of it

262 background, which contains a polyadenylation signal sequence that stabilizes DUX4 mRNA.

263 d breaks adjacent to conserved recombination signal sequences that contain either 12- or 23-nucleotid

264 rt of the substrate SidJ is mediated by dual signal sequences that include a conventional C-terminal

265 lar experiments on nascent chains containing signal sequences that may form compacted structural moti

266 nto the endoplasmic reticulum is mediated by signal sequences that vary widely in primary structure.

267 te homologues, which have typical N-terminal signal sequences, the precursor form of Drosophila Hh co

268 ation of unfolded preproteins containing Sec signal sequences through the SecYEG membrane channel.

269 EsxB binds via its signal sequence to an empty pocket on the C-terminal ATP

270 s to the translating ribosome displaying the signal sequence to deliver it to the SRP receptor (SR) o

271 ra transgene is fused with an amino-terminal signal sequence to facilitate delivery of the chimera to

272 (APP47) and Abeta1-42 (APP48) with a cleaved signal sequence to insert both peptides during synthesis

273 We have mapped IRS1 degradation signal sequence to its N-terminal 574 amino acid residue

274 ascent chain complexes (RNCs) that display a signal sequence to protein translocation channels in tar

275 The transfer of this signal sequence to the N terminus of heterologous amyloi

276 Many secretory proteins are targeted by signal sequences to a protein-conducting channel, formed

277 reby permitted D(H)-associated recombination signal sequences to initiate the second step of Igh gene

278 me-nascent chain complexes (RNCs) displaying signal sequences to protein translocation channels in th

279 ptimized Bb virulence factors, including the signal sequence, to the Escherichia coli membrane, of wh

280 and the RAPTOR subunit that binds to the Tor signalling sequence (TOS) motif of substrates and regula

281 When expressed in Escherichia coli with PelB signal sequences, TprC and TprI localize to the outer me

282 provides new insights into the mechanism of signal sequence transfer from the SRP to the translocon.

283 use for L lactis and joined with a linker; a signal sequence was added to allow for product secretion

284 -region of the alpha-mating factor secretion signal sequence was performed in order to determine the

285 embrane form of EDEM1 was generated when the signal sequence was uncleaved, creating an N-terminal tr

286 hich lacks a classical, cleavable N-terminal signal sequence, was found to be secreted during the sta

287 binding domains that are distinct from both signal sequences were elucidated and, interestingly, onl

288 ing to target was induced when the exchanged signal sequences were identical, or when only a single e

289 the exchanged signals, or when the variable signal sequences were produced by a single entity alone,

290 tein (GFP) cassette flanked by recombination signal sequences were transduced with retroviruses encod

291 It was initially proposed that SRP binds the signal sequence when it emerges from an RNC and that suc

292 ntronic region containing the distal poly(A) signal sequences, when transferred to a heterologous min

293 hBFIT2) constitutes a mitochondrial location signal sequence, which undergoes mitochondrion-dependent

294 of nucleosomes with respect to recombination signal sequences, which could be nucleosomal or internuc

295 All the proteins had an N-terminal signal sequence with a putative sorting signal of L(P/T/

296 es could be bypassed by replacing the PrP(C) signal sequence with that of prolactin or osteopontin.

297 mplex formation occurs between recombination signal sequences with unequal 12 and 23 base spacer sequ

298 Only recombination between signal sequences with unequal spacers results in product

299 dergo synapsis with a standard recombination signal sequence within the cells, in a RAG-dependent man

300 arly recruitment of SRP to RNCs containing a signal sequence within the ribosomal tunnel is NAC depen