ライフサイエンスコーパス: signaling protein

1 action of TRAF3 with mitochondrial antiviral signaling protein.

2 trafficking complex and FtsEX cell division signaling protein.

3 lock to directing trafficking of another key signaling protein.

4 -derived signals in which Hic-5 is a pivotal signaling protein.

5 s complex binding systems typically found as signaling proteins.

6 roach is providing a deeper understanding of signaling proteins.

7 ibosomal proteins, polymerases, enzymes, and signaling proteins.

8 ocalization of many receptors, channels, and signaling proteins.

9 f the p-AKT1, p-EIF4EBP1, p-RPS6 and p-EIF4E signaling proteins.

10 CRs) are the largest family of transmembrane signaling proteins.

11 s covalently linked to proteases that cleave signaling proteins.

12 rolling the expression of genes encoding ABA signaling proteins.

13 otility, cytoskeleton-membrane scaffolds and signaling proteins.

14 e expression patterns and phosphorylation of signaling proteins.

15 ization might regulate the function of other signaling proteins.

16 osttranslational regulation on cell survival signaling proteins.

17 modynamic barriers for binding of downstream signaling proteins.

18 tating the functions of poorly characterized signaling proteins.

19 nd regulate the activities of many important signaling proteins.

20 s on a newly quantified gradient in upstream signaling proteins.

21 leoporins, mRNA-processing enzymes, and cell-signaling proteins.

22 lation with phosphorylation of intracellular signaling proteins.

23 Slack channels binds a number of cytoplasmic signaling proteins.

24 and is required for the folding of numerous signaling proteins.

25 in cytoskeleton through numerous adaptor and signaling proteins.

26 elopment of modulators targeting families of signaling proteins.

27 t pleckstrin homology (PH) domain-containing signaling proteins.

28 phopeptide recognition modules found in many signaling proteins.

29 , and increased abundance of hepatic insulin signaling proteins.

30 toplasmic domain to expose docking sites for signaling proteins.

31 mulus-dependent palmitoylation of downstream signaling proteins.

32 mediating interactions with cytoskeletal and signaling proteins.

33 induced phosphorylation levels of downstream signaling proteins.

34 ir downstream effects by activating distinct signaling proteins.

35 endritic nucleation confirmed a role for Wnt signaling proteins.

36 n altered spatial relationship between these signaling proteins.

37 tin sites implicated in scaffolding distinct signaling proteins.

38 sitive and specific assays for low-abundance signaling proteins.

39 revious successes on bacterial two-component signaling proteins.

40 roup encoding both transcription factors and signaling proteins.

41 ss organelles to the cooperative assembly of signaling proteins.

42 s to control the activity of cilia-localized signaling proteins.

43 estigations of clustering behaviors in other signaling proteins.

44 , where they recruit and anchor a variety of signaling proteins.

45 d secretion of the pro-repair WNT1-inducible signaling protein 1 (WISP-1).

46 e, we show that GSCs secrete the Wnt-induced signaling protein 1 (WISP1) to facilitate a pro-tumor mi

47 lated at Ser(701), leading to binding of the signaling protein 14-3-3beta.

48 on the recognition of regulator of G protein signaling protein 2 (RGS2) by its E3 ligase, increasing

49 Cellular response is initiated through a signaling protein (a receptor), which interacts with the

50 ns, body composition by DEXA, tissue insulin signaling protein abundance by Western blotting, glucose

51 by secreting antioxidants and the lipogenic signaling protein Acb1.

52 evaluation of the phosphorylation status of signaling proteins across different B cell subpopulation

53 ast decade, multiple studies have shown that signaling proteins activated in different temporal patte

54 n NK cells selectively lacking expression of signaling proteins after human cytomegalovirus (HCMV) in

55 ential roles of both mitochondrial antiviral signaling protein and myeloid differentiation primary re

56 These included key CTL effector molecules, signaling proteins and a subset of metabolic enzymes.

57 PPKs phosphorylate light-signaling proteins and histones to affect plant developm

58 K autophosphorylation selects the downstream signaling proteins and lipids to effect growth factor an

59 Many signaling proteins and lipids with important functions i

60 Here, we used short-lived auxin signaling proteins and model N-end rule (N-recognin) pat

61 on as intercellular messengers by delivering signaling proteins and noncoding RNAs to alter target ce

62 nstitute the largest family of transmembrane signaling proteins and the largest pool of drug targets,

63 ributable to differential regulation of cell signaling proteins and their transcription factors, appr

64 imately 100 aa that bind phosphotyrosines in signaling proteins and thereby mediate intra- and interm

65 ke up the dystrophin complex, a scaffold for signaling proteins and transporters at the cell membrane

66 matory control, cell survival, intracellular signaling, protein and lipid homeostasis, and clotting p

67 pression, activation states of intracellular signaling proteins, and cytokine production.

68 ive oxygen species (ROS)-generating enzymes, signaling proteins, and downstream executors such as ion

69 found in eukaryotic phosphate transporters, signaling proteins, and inorganic polyphosphate polymera

70 epeat sequences, protein kinases and defense signaling proteins, and previously mentioned defense pro

71 lls communicate with each other by secreting signaling proteins, and the blood is a key conduit for t

72 We propose that in dendrites, canonical Wnt signaling proteins are housed on early endosomes and rec

73 Although the concentrations of signaling proteins are perturbed in disease states, such

74 to probe the structure-function relations of signaling proteins are still underexplored.

75 We show that agouti signaling protein (ASIP) and beta-carotene oxygenase 2 (

76 ls, spatially regulated expression of agouti-signaling protein (ASIP) generates the difference in sha

77 l implants increase the expression of agouti signaling protein (ASIP) mRNA in skin, likely explaining

78 feather development or pigmentation: agouti signaling protein (ASIP), follistatin (FST), ecodysplasi

79 gene transcript, and two antagonists, agouti-signaling protein (ASP) and agouti-related protein (AGRP

80 eases with increasing levels of CheA, a core signaling protein associated with the receptors, whereas

81 d movement, we imaged various structural and signaling proteins at cell-cell and cell-matrix junction

82 insight into tissue origin and the wiring of signaling proteins at membranes to predict onset and beh

83 nt of affinity-sensors and the prediction of signaling protein based drug efficiency.

84 The Wnt signaling protein BCL9L is upregulated in soft tumor cel

85 ss and inducing nuclear translocation of the signaling protein beta-catenin.

86 antagonists human beta-defensin 3 and agouti signaling protein blocked MSH- but not forskolin-mediate

87 s) that target genes encoding known thrombin signaling proteins blocks effectively thrombin-induced j

88 res reorganization of receptors and membrane signaling proteins, but this spatial regulation is not w

89 orrect distribution and activity of secreted signaling proteins called morphogens is required for man

90 c, subcellular perturbation of an individual signaling protein can help to determine its role in cont

91 we focus on mechanochemical feedback, where signaling proteins can establish patterns via coupling t

92 features, alternative splicing variants, and signaling proteins change their abundance, localization,

93 onses often involve endosomal trafficking of signaling proteins; coincidently, endosomes serve as sig

94 o differentially activate phosphorylation of signaling proteins compared with IL-1beta.

95 affold but recruits a distinct repertoire of signaling proteins compared with SgK269.

96 tions and function to scaffold intracellular signaling protein complexes.

97 act as molecular scaffolds along with other signaling proteins, complicating the interpretation of e

98 Several classes of signaling proteins contain autoinhibitory domains that p

99 In turn, PI3P recruits an array of signaling proteins containing PI3P-specific targeting do

100 phosphorylation sites can recruit downstream signaling proteins containing Src homology 2 (SH2) and p

101 membrane lipid composition, morphology, and signaling protein content, and suggest that this conserv

102 r the direct chemical activation of specific signaling proteins could provide powerful tools for inte

103 Other At-RBP set proteins include major signaling proteins, cytoskeleton-associated proteins, me

104 hosphorylated and associated with downstream signaling proteins, demonstrating that the molecular den

105 rs to stimulate the same suite of downstream signaling proteins, different agonists are capable of in

106 Signaling proteins dominated the screen and among them,

107 f 8-OH-DPAT increased the phosphorylation of signaling proteins downstream of BDNF, including mTOR, E

108 hosphorylated mTOR and protein kinase B, the signaling proteins downstream of mGlu5 activation, were

109 ling network in HEK293T cells, we analyze 20 signaling proteins during a 1-h EGF stimulation time cou

110 Little is known whether signaling proteins [e.g., G protein-coupled receptors (G

111 stem are controlled by molecules such as the signaling protein endothelin 3 (EDN3), its receptor (the

112 Our results suggest that C1ql3 is a signaling protein essential for subsets of synaptic proj

113 Signaling proteins exemplified by calmodulin usually bin

114 igments, and other phototransduction cascade signaling proteins expressed in these eyes are related t

115 e hypothesized that alterations in glutamate signaling protein expression and co-expression network f

116 ceramide levels 2-fold, inactivated the key signaling protein extracellular signal-regulated kinase,

117 ing converge to induce the expression of the signaling proteins FBJ osteosarcoma oncogene (c-FOS, enc

118 LZF), as well as expression of intracellular signaling proteins FcepsilonRgamma, spleen tyrosine kina

119 ed by the lack of the regulator of G-protein signaling protein FlbA.

120 s (FKBPs) are pivotal modulators of cellular signaling, protein folding, and gene transcription.

121 n factor NF-kappaB, ubiquitination, cytokine signaling, protein folding, type I interferon production

122 The mesoderm is specified by secreted signaling proteins from the FGF, Nodal, BMP and Wnt fami

123 Numerous DNA repair and signaling proteins function at DNA damage sites to prote

124 he clustering and activation of caveolin and signaling proteins further stabilize raft structure and

125 Sonic hedgehog (Shh) is a multifunctional signaling protein governing pattern formation, prolifera

126 en species, ABA biosynthesis, the retrograde signaling protein GUN1, and ABI4.

127 GF-beta and bone morphogenetic protein (BMP) signaling proteins has numerous developmental and physio

128 Further, we show that upstream signaling proteins have abundance-dependent effects on d

129 Many regulatory and signaling proteins have multiple modification sites.

130 nase protein family, bacterial transmembrane signaling proteins implicated in the regulation of cell

131 actors have emerged as an important group of signaling proteins in bacteria involved in many regulato

132 ntology analysis revealed decreased synaptic signaling proteins in CAPN5-NIV vitreous compared to con

133 changes in production and activation of host signaling proteins in decidualized telomerase-immortaliz

134 ontexts, so we tested the involvement of Wnt signaling proteins in dendrite regeneration.

135 d functional diversification of chemosensory signaling proteins in filarial worms and encourage a mor

136 hway composed of the T4P upstream of the Dif signaling proteins in M. xanthus.

137 (LRR-RKs) form the largest group of membrane signaling proteins in plants.

138 dehyde dehydrogenase (ALDH) activities and 5 signaling proteins in single MDA-MB-231 breast cancer ce

139 try the copy number of nineteen chemosensory signaling proteins in sperm flagella from the sea urchin

140 oglycans that function as receptors of these signaling proteins in the liver are commonly decorated b

141 me varies with relative stoichiometry of the signaling proteins in the phase-separated clusters, rend

142 the hope that expression of light-activated signaling proteins in the surviving cells could restore

143 ased the expression of CSC-markers and notch signaling proteins in tumor tissues.

144 splayed decreased phosphorylation of several signaling proteins including Src and GSK3beta.

145 We recently found that Wnt signaling proteins, including dsh and Axin, localize mic

146 ropagate to the spatial recruitment of early signaling proteins, including spleen tyrosine kinase (Sy

147 ng protein (MAVS), which recruits additional signaling proteins, including TNF receptor-associated fa

148 a signaling network composed of hundreds of signaling proteins interacting with each other extensive

149 positive allosteric facilitators of receptor-signaling protein interaction.

150 ongs to a gene superfamily encoding TGF-beta-signaling proteins involved in bone and cartilage biolog

151 id enrichment serves as docking platform for signaling proteins involved in many processes including

152 However, receptors and downstream signaling proteins involved in TGF-beta1-induced hepcidi

153 F-beta) network of ligands and intracellular signaling proteins is a subject of intense interest with

154 A common design principle of heteromeric signaling proteins is the use of shared subunits.

155 structure where the lateral organization of signaling proteins is tightly regulated.

156 , a negative regulator of multiple oncogenic signaling proteins, is a promising therapeutic approach

157 much is known about how scaffolds colocalize signaling proteins, it is unclear whether scaffolds prom

158 e the regulation of short-term growth factor signaling (protein kinase B (PKB/Akt) activity) and long

159 gives rise to MVs, which uniquely contain a signaling protein kinase that helps propagate the transf

160 Allosteric switches introduced into motility signaling proteins (kinases, guanosine triphosphatases,

161 The resulting release of pro-apoptotic signaling proteins leads to cell destruction through act

162 factors (FHFs) are a family of intracellular signaling proteins linked with Nav channel regulation in

163 The signaling protein MALT1 plays a key role in promoting NF

164 the function of the mitochondrial antiviral signaling protein MAVS, implicating PB2 in the regulatio

165 and inactivating the antiviral innate immune signaling proteins MAVS and Riplet, which are essential

166 s) interact with the mitochondrial antiviral signaling protein (MAVS) and activate TANK-binding kinas

167 by interacting with mitochondrial antiviral signaling protein (MAVS) and inhibiting its association

168 Mice lacking mitochondrial antiviral-signaling protein (MAVS) and mice lacking stimulator of

169 VHSV-IVb) suppressed mitochondrial antiviral signaling protein (MAVS) and type I IFN-induced gene exp

170 ormational change in mitochondrial antiviral signaling protein (MAVS) but not with a reduction in the

171 ed on stimulation of mitochondrial antiviral-signaling protein (MAVS) by the antimicrobial peptide LL

172 The mitochondrial antiviral signaling protein (MAVS) is a central signal transductio

173 (shRNA) knockdown of mitochondrial antiviral signaling protein (MAVS) or interferon regulatory factor

174 egative regulator of mitochondrial antiviral signaling protein (MAVS) that is critical for antiviral

175 art, is dependent on mitochondrial antiviral signaling protein (MAVS) to stimulate type I interferons

176 on of PGAM5 with the mitochondrial antiviral-signaling protein (MAVS) was demonstrated.

177 gene 1 (RIG-I), and mitochondrial antiviral signaling protein (MAVS), and subsequently induced IFN r

178 h the CARD domain in mitochondrial antiviral signaling protein (MAVS), boosting NF-kappaB-driven tran

179 by TRIM25 and binds mitochondrial antiviral signaling protein (MAVS), leading to the production of t

180 termined the role of mitochondrial antiviral-signaling protein (MAVS), the adaptor protein for RIG-I

181 termined the role of mitochondrial antiviral signaling protein (MAVS), the adaptor protein for RIG-I-

182 of mice deficient in mitochondrial antiviral-signaling protein (MAVS), the signaling adaptor for RNA

183 the adaptor protein mitochondrial antiviral signaling protein (MAVS), which recruits additional sign

184 Thus, multiple signaling proteins may compete for binding to a common S

185 cid-inducible gene I/mitochondrial antiviral-signaling protein-mediated RNA-sensing pathway.

186 Additionally, mitochondrial antiviral signaling protein-mediated signaling through cytosolic p

187 For instance, paralogous signaling proteins must acquire mutations that endow the

188 omeostasis is that regulated by the secreted signaling proteins, myostatin (MSTN) and activin A.

189 tem provides a rare opportunity to study how signaling proteins natively gain distinct function.

190 behaviors are delineated by the multifaceted signaling protein neurofibromin 1 (NF1).

191 ansmitter-modulator receptors, ion channels, signaling proteins, neuropeptides and vesicular release

192 The transmembrane signaling protein Notch, which is crucial for embryonic

193 ytometry data sets, measuring intra-cellular signaling proteins of the human immune system and their

194 ribosylation of Smad3 and Smad4, two central signaling proteins of the pathway.

195 RGS (regulator of G protein signaling) proteins of the R7 subfamily (RGS6, -7, -9, a

196 Moreover, ANO8 assembles all core Ca(2+) signaling proteins: Orai1, PMCA, STIM1, IP(3) receptors,

197 Among them, FHL2 and the M-band signaling proteins p62 and Nbr1 are exclusively upregula

198 This organelle and its requisite signaling protein, PC1, are required for critical elemen

199 report a negative feedback loop between the signaling protein phospholipase D (PLD), phosphatidic ac

200 ase in the phosphorylation of the downstream signaling protein, PKC-alpha, and Ca(2+)/calmodulin-depe

201 The role that signaling proteins play to establish a tumor microenviro

202 that arrestins, multifunctional adapter and signaling proteins, play a vital role in mediating the s

203 HS interacts with many signaling proteins potentially encoding numerous selecti

204 umor growth in part through secretion of the signaling protein prosaposin.

205 singly, targets are almost exclusively other signaling proteins, rather than cytoskeletal components,

206 sing Drosophila, we found that canonical Wnt signaling proteins regulate localization of the core nuc

207 the adaptor protein mitochondrial antiviral signaling protein, regulates NF-kappaB-mediated inductio

208 The intracellular signaling protein regulator of presynaptic morphology 1

209 ns of GPCRs, and their downstream regulatory signaling proteins (regulator of G-protein signaling 2,

210 he expression and phosphorylation of insulin signaling proteins remained comparable among APP, ApoE3x

211 ulate and control assembly of such composite signaling proteins remains an important open question.

212 ease cleaves a human mitochondrial antiviral signaling protein reporter, providing a sensitive readou

213 th each other as well as other receptors and signaling proteins, resulting in functional complexes ca

214 Moreover, inhibition of these signaling proteins reversed chemoresistance in in vitro

215 V-1 was determined by phosphorylation of the signaling protein ribosomal S6.

216 KaiB, and KaiC proteins and a set of output signaling proteins, SasA and CikA, which transduce this

217 ocal regulation of the mutually antagonistic signaling proteins, SasA and CikA.

218 ruit RACK1 and Raptor, two TRAPP-interactive signaling proteins, sensitizing cells to stress-induced

219 For signaling proteins, several recent studies have shown ho

220 critical role of the mitochondrial antiviral signaling protein signaling pathway in IFN-I production

221 SltA and the putative pseudokinase/protease signaling protein SltB comprise a regulatory pathway spe

222 e transforming growth factor beta (TGF-beta) signaling proteins, SMAD family member 2 (SMAD2) and 3 (

223 transforming growth factor (TGFbeta) and its signaling protein Smad3, known contributors to IH.

224 that NUP93 and exportin 5 interact with the signaling protein SMAD4 and that NUP93 mutations abrogat

225 They offer physical platforms to downstream signaling proteins so that their transient interactions

226 The signaling protein Sonic Hedgehog (SHH) is crucial for th

227 living cell provides a platform for receptor signaling, protein sorting, transport, and endocytosis,

228 ctional analyses implicating the rat sarcoma signaling protein, SOS1 (Son of sevenless homolog 1), in

229 CR phosphorylation was triggered, downstream signaling proteins spontaneously separated into liquid-l

230 in a manner that requires the presence of a signaling protein Sprouty-2.

231 0 enhanced activation of the key FcepsilonRI signaling proteins Stat5, JNK, and ERK.

232 Here we show that the innate immune signaling protein STING is required for efficient replic

233 The Suppressor of TCR signaling proteins (Sts-1 and Sts-2) are two homologous

234 findings suggest that microtubule-associated signaling proteins such as EB3 cooperate with actin remo

235 plex acts as a cargo adapter that recognizes signaling proteins such as GPCRs and links them to the i

236 cent studies we show that alpha7 nAChRs bind signaling proteins such as heterotrimeric GTP-binding pr

237 ty by influencing the activity of downstream signaling proteins such as histidine kinases (HisKa) in

238 Signaling proteins such as protein kinases adopt a diver

239 These included plasma-membrane-localized signaling proteins such as receptor-like kinases, aspart

240 such as IFIT1, IFIT2, and IFIT3, as well as signaling proteins such as STAT1, STAT2, and MAVS, were

241 sh this, GPCRs first bind to an intermediary signaling protein, such as G protein or arrestin.

242 lated brain regions, and reduced hippocampal signaling proteins, such as brain-derived neurotrophic f

243 We also found that signaling proteins, such as STAT3, Raf1, and PKCzeta, we

244 We also found that signaling proteins, such as STAT3, Raf1, and PKCzeta, we

245 i-protein complex also containing downstream signaling proteins, such as TAK1, IKKs, and PP2A, that i

246 In addition, FLNs serve as scaffolds for signaling proteins, such as tyrosine kinases, GTPases, o

247 henotypes included increased PI3K downstream signaling, protein synthesis rates, and dendritic spine

248 e mechanical load-induced regulation of mTOR signaling, protein synthesis, and skeletal muscle hypert

249 We investigated the link between cytokinin signaling, protein synthesis, plant growth and osmotic s

250 s a ubiquitin-binding autophagy receptor and signaling protein that accumulates in premalignant liver

251 f three human malignancies, and KSHV K1 is a signaling protein that has been shown to be involved in

252 Hedgehog (Hh) is an evolutionarily conserved signaling protein that has essential roles in animal dev

253 Angiopoietin-like 4 (ANGPTL4) is a secreted signaling protein that is implicated in cardiovascular d

254 RGS14 is a multifunctional signaling protein that suppresses synaptic plasticity in

255 activates FLOWERING LOCUS T1 (FT1), a mobile signaling protein that travels from the leaves to the sh

256 Rather, GPCRs are dynamic signaling proteins that adopt distinct conformations and

257 Cilia house signaling proteins that allow the cell to sample their e

258 LAT) and phospholipase C-gamma1 (PLCgamma1), signaling proteins that are traditionally considered to

259 ly, we show that three critical postsynaptic signaling proteins that bind to the PDZ domains of PSD-9

260 veals downregulation of several postreceptor signaling proteins that contribute to this resistance.

261 cell receptor (TCR), the race was on to map signaling proteins that contributed to T cell activation

262 his study implicates new pathways and immune signaling proteins that may be associated with posterior

263 Wnt proteins are a family of secreted signaling proteins that play key roles in regulating cel

264 The Wnt family of proteins are secreted signaling proteins that play key roles in regulating cel

265 ellular guidance molecules and intracellular signaling proteins that regulate axonal outgrowth and ex

266 dentified that polarizes the distribution of signaling proteins that restricts growth to cell ends an

267 ein-coupled receptors (GPCRs) are allosteric signaling proteins that transmit an extracellular stimul

268 -protein-coupled receptors (GPCRs) are major signaling proteins that undergo multiple types of PTMs.

269 ases of the RAS and RHO families are related signaling proteins that, when activated by growth factor

270 onco-Dbl-transformed cells contain a unique signaling protein, the ubiquitously expressed non-recept

271 f a receptor respond to different ligands or signaling proteins through modulation of fast ps-ns side

272 rification mass spectrometry for the LTbetaR signaling protein TNFR-associated factor 3 (TRAF3).

273 and interacted with mitochondrial antiviral signaling protein to induce type I/III interferons (IFNs

274 fecting the expression of genes encoding ABA signaling proteins to affect ABA sensitivity.

275 rved-region 2 (C2) domains target their host signaling proteins to anionic membranes.

276 ays of 878 antibodies directed against human signaling proteins to interrogate the activation status

277 li and inputs, using an extraordinary set of signaling proteins to process this information and make

278 -cell analysis with overexpression of tagged signaling proteins to study the dependence of signaling

279 Indeed, cells in all organisms rely on these signaling proteins to survive and proliferate in unpredi

280 y proteins such as transcription factors and signaling proteins to target genes.

281 mechanisms linking the function of membrane signaling proteins to the composition and physical prope

282 etween the stepwise recruitment of ZAP70 and signaling proteins to the TCR, as well as distinct patte

283 tion of USP7 interactions with innate immune signaling proteins TRAF3 and TRAF6, and that vIRF-2 targ

284 Membrane signaling proteins transduce information across lipid bi

285 late additional mutations affecting JAK/STAT signaling, protein translation, and epigenetic control,

286 homolog regulates membrane morphogenesis and signaling protein transport in specialized sensory cilia

287 n which temporal regulation of a pleiotropic signaling protein underlies cortical circuit maturation

288 Protocadherins (Pcdhs) are cell adhesion and signaling proteins used by neurons to develop and mainta

289 ork by which RALF ligands instruct different signaling proteins using distinct targeting mechanisms.

290 nanoparticle (NP1) engineered to bind a key signaling protein, vascular endothelial growth factor (V

291 se in the levels of Ku80 and some downstream signaling proteins was prevented by CRISPR-Cas9-mediated

292 carbonic anhydrase, stress, degradation and signaling proteins were more abundant while proteins ass

293 Using these models, we also identify which signaling proteins were useful in predicting patient the

294 elopmental factors is a robust repertoire of signaling proteins, which have arisen from extensive gen

295 s an anti-inflammatory microRNA that targets signaling proteins, which mediate inflammatory responses

296 cellular signaling and is thought to provide signaling proteins with additional regulatory mechanisms

297 , and -beta3, are small secreted homodimeric signaling proteins with essential roles in regulating th

298 tics, spatial distribution, and diffusion of signaling proteins within the contact.

299 iate fitting models of a GFP tagged secreted signaling protein, Wnt3, in live zebrafish embryos, whic

300 tes markedly increased the expression of Wnt signaling proteins (Wnt3a, Wnt5a, Wnt10b, LRP5, and beta