ライフサイエンスコーパス: single molecule imaging

1 ral organization of EqtII in living cells by single molecule imaging.

2 ian dynein using in vitro reconstitution and single molecule imaging.

3 with the aim of optimising this approach for single molecule imaging.

4 ear x-ray optics and high field physics, and single molecule imaging.

5 by cosedimentation, electron microscopy, and single-molecule imaging.

6 ques and access to a microscope equipped for single-molecule imaging.

7 ecovery after photobleaching experiments and single-molecule imaging.

8 es both challenges and dramatically improves single-molecule imaging.

9 r unamplified nucleic acids that is based on single-molecule imaging.

10 t for two-photon, fluorescence lifetime, and single-molecule imaging.

11 l dynamics of NHEJ complexes using live cell single-molecule imaging.

12 lgorithmic advancements for high-fidelity 3D single-molecule imaging.

13 re soft-landed on a surface for their direct single-molecule imaging.

14 rns on millions of individual nucleosomes by single-molecule imaging.

15 ations common to fluorescence microscopy and single-molecule imaging.

16 from routine gel electrophoresis to advanced single-molecule imaging.

17 NA FluoroCubes provide outstanding tools for single-molecule imaging, allowing the tracking of single

18 that expressing these nanobodies coupled to single-molecule imaging-amenable tags could allow superr

19 Single-molecule imaging analysis shows that cholesterol

20 Here we have used live-cell single molecule imaging and deep sequencing to assess de

21 Here, we have used combination of single molecule imaging and genomic approaches to explor

22 lastically coupled reactions is proposed for single molecule imaging and rotor manipulation experimen

23 e of ~100 mum are essential for simultaneous single molecule imaging and single ion-channel electrica

24 We address this issue by single molecule imaging and tracking in fibroblast peric

25 response are not well understood, so we used single-molecule imaging and AFM cantilever deflection to

26 gs enable rational nanoprobe engineering for single-molecule imaging and also reveal counter-intuitiv

27 Here we present a single-molecule imaging and analysis platform using scie

28 g a combination of cryo-electron microscopy, single-molecule imaging and cell-based signalling approa

29 DNA by integrating fluorescence measurement, single-molecule imaging and computational modeling.

30 allel assays, cryogenic electron microscopy, single-molecule imaging and CRISPR-Cas9 screening.

31 Here we combine single-molecule imaging and cryogenic electron microscop

32 Combining single-molecule imaging and deep sequencing, we show tha

33 single-cell sequencing data, as well as from single-molecule imaging and electron micrographs of fixe

34 ecules by the dye YOYO-1 using complementary single-molecule imaging and gel electrophoresis-based da

35 Single-molecule imaging and manipulation of biochemical

36 Combination of single-molecule imaging and microfluidic-based single-ce

37 ly well suited for applications in live-cell single-molecule imaging and multiplexed cellular labelin

38 Using single-molecule imaging and optical trapping assays, we

39 Here we use single-molecule imaging and optical trapping to show tha

40 ange of localization applications, including single-molecule imaging and particle tracking, in fields

41 Recently, single-molecule imaging and photocontrol have enabled su

42 such heterogeneity, we used a combination of single-molecule imaging and reversed-phase liquid chroma

43 e and a combination of techniques, including single-molecule imaging and single-particle electron mic

44 is hand-in-hand with the new development of single-molecule imaging and spectroscopic technology and

45 For this study, we used single-molecule imaging and ssDNA curtains to examine th

46 chers need to have substantial experience in single-molecule imaging and statistical analysis to cond

47 , we present a method combining high-density single-molecule imaging and statistical inference to sep

48 We used single-molecule imaging and stepwise photobleaching in X

49 Leveraging light-sheet single-molecule imaging and synthetic condensates, we de

50 eriments studying a variety of bacteria with single-molecule imaging and tracking during real-time en

51 Here we use single-molecule imaging and tracking to characterize the

52 Here, we use stroboscopic single-molecule imaging and tracking to probe the dynami

53 duce off-target CRISPR base editing, improve single-molecule imaging, and allow live tracking of aden

54 ns in single cells, mRNA and nascent protein single-molecule imaging, and bulk RNA and protein detect

55 e prediction, molecular dynamics simulation, single-molecule imaging, and mutagenesis.

56 d photostability, phototoxicity in live-cell single-molecule imaging, and use of new labels for nanos

57 cribe new approaches of subunit labeling for single-molecule imaging, applied to determine the TERT c

58 Here, we developed a single-molecule imaging approach based on a HaloTag fusi

59 We have developed a single-molecule imaging approach for investigating the f

60 (2020) use an innovative single-molecule imaging approach in yeast cells to measu

61 orescence in situ hybridization (MERFISH), a single-molecule imaging approach that allows the copy nu

62 discussion is given on the extension of the single-molecule imaging approach to catalysis that does

63 Here, we have developed a single-molecule imaging approach to monitor the recruitm

64 We use a single-molecule imaging approach to visualize the intera

65 ochemical, biophysical and super-resolution, single molecule imaging approaches demonstrated that the

66 Single molecule imaging approaches like dSTORM and PALM

67 Using a combination of in vitro and in vivo single-molecule imaging approaches, we directly correlat

68 Using single-cell profiling and multimodal single-molecule imaging approaches, we have found that s

69 more recently developed single-filament and single-molecule imaging approaches.

70 These results establish high-speed single-molecule imaging as a new tool for mapping the st

71 he foundation for harnessing high-resolution single-molecule imaging as the next frontier for develop

72 ides a powerful tool for long-term live-cell single-molecule imaging, as demonstrated by the imaging

73 Here, we describe a single-molecule imaging assay that 1) utilizes compariso

74 Combining three single-molecule imaging assays in living cells together

75 index can act as lenses that are capable of single-molecule imaging at 70 degrees C when placed in i

76 ing monomer pool to achieve fast, continuous single-molecule imaging at optimal densities with signal

77 Single-molecule imaging at the tissue scale has revoluti

78 Using a combination of single-molecule imaging, biochemistry and electrophysiol

79 used three-dimensional electron microscopy, single-molecule imaging, biochemistry, and in vivo assay

80 low fluorophore concentrations required for single molecule imaging, both of which may bias native s

81 Here, we use single molecule imaging by atomic force microscopy (AFM)

82 Single-molecule imaging by means of atomic force microsc

83 We demonstrated two-color single-molecule imaging by observing the spatiotemporal

84 are applied for the first time to high-speed single-molecule imaging by tracking their lateral mobili

85 Our results demonstrate that the STM-based single-molecule imaging can capture a thorough picture o

86 Here, we applied single molecule imaging capable of detecting long-lived

87 Multispectral single-molecule imaging confirmed that VopF molecules as

88 In mammalian cell culture, single-molecule imaging confirms hexameric IL-5 complex

89 Our real-time single-molecule imaging data demonstrate that TFIID alon

90 rate tracking), combining dynamic but sparse single-molecule imaging data with almost-whole populatio

91 on kinetics in their native environment from single-molecule imaging data with substoichiometric labe

92 of in Situ Interaction Kinetics (FISIK) from single-molecule imaging data with substoichiometric labe

93 two types of nanopores were deduced from the single-molecule imaging data.

94 Applying our approach to two single-molecule imaging datasets across different genomi

95 Single-molecule imaging demonstrated physical anticorrel

96 Furthermore, single-molecule imaging directly demonstrates that proce

97 several techniques (polarization microscopy, single-molecule imaging, emission time dependence, energ

98 ts have been pushing the limits of live-cell single-molecule imaging, enabling the monitoring of inte

99 We have established a single-molecule imaging experimental platform called "DN

100 The analysis of live-cell single-molecule imaging experiments can reveal valuable

101 The number of reports per year on single-molecule imaging experiments has grown roughly ex

102 Single-molecule imaging experiments have shed new light

103 Consistent with simulations, live-cell single-molecule imaging experiments showed that a fast o

104 e relevant for the interpretation of in vivo single-molecule imaging experiments, bacterial photosynt

105 suggesting that UCNPs are ideally suited for single-molecule imaging experiments.

106 Single molecule imaging further reveals that hexameric C

107 The development of probes for single-molecule imaging has dramatically facilitated the

108 tobleach recovery, fluorescence correlation, single-molecule imaging) have been adapted to measure mo

109 Our technology thus paves the way toward single molecule imaging in cells and living animals, all

110 Most assays and single molecule imaging in live hippocampal neurons reve

111 us, by combining direct genetic labeling and single molecule imaging in vivo, our work establishes an

112 Here, we use single-molecule imaging in a vertebrate cell-free extrac

113 hesized dyes are modifiable and suitable for single-molecule imaging in biological and medical scienc

114 ce light-sheet microscopy to perform in vivo single-molecule imaging in early Drosophila melanogaster

115 Here, we use live-cell single-molecule imaging in human cells to determine rate

116 e review how new advances in superresolution single-molecule imaging in live cells can track transcri

117 Single-molecule imaging in live cells has illuminated th

118 Here, we use single-molecule imaging in live cells to directly study

119 Using single-molecule imaging in live cells, we directly visua

120 In this study, we use single-molecule imaging in live E. coli cells to investi

121 ng and unbinding events in space and time by single-molecule imaging in live primary T cells for a ra

122 on simulated data as well as real data from single-molecule imaging in living cells.

123 SMAC opens the door to the application of single-molecule imaging in noninvasive disease profiling

124 Here, we used single-molecule imaging in reconstituted morphogen gradi

125 It can also be used for single-molecule imaging in the presence of high concentr

126 Single-molecule imaging in this thick polysaccharide mat

127 Using three-color single-molecule imaging in vitro we revealed how the dyn

128 Single-molecule imaging is used for the first time to st

129 dies emphasize the importance of controls in single-molecule imaging measurements, and indicate that

130 We report a high-resolution, single-molecule imaging method to probe CI-mediated DNA

131 Using single cell and single molecule imaging methods (fluorescence resonance

132 Here, we use kinetic and single molecule imaging methods to monitor RECQ5 behavio

133 However, standard single-molecule imaging methods based on overexpressed g

134 However, thus far, single-molecule imaging methods have not been translated

135 ments of complex stoichiometry than existing single-molecule imaging methods.

136 Using single molecule imaging of a fluorescent phospholipid, t

137 onjugation to streptavidin for high-affinity single molecule imaging of biotinylated receptors on liv

138 Using dual color single molecule imaging of cFos alone, we directly visua

139 Single molecule imaging of DNA isolated from peripheral

140 Single molecule imaging of eGFP-PspA and its amphipathic

141 Single molecule imaging of motility in cell extracts dem

142 Single molecule imaging of p44/p62 complexes without XPD

143 Moreover, single-molecule imaging of a Cy3-labeled agonist, [Lys(7

144 tly visualized in dendrites and spines using single-molecule imaging of a diffusion-restricted Venus-

145 We demonstrated single-molecule imaging of a model tumor marker (EGFR) o

146 Single-molecule imaging of biological macromolecules has

147 escence turn-on probe that enables sustained single-molecule imaging of cellular membranes under stro

148 We carried out single-molecule imaging of CHD4 in live mouse embryonic

149 Dynamic single-molecule imaging of Complexin binding to release-

150 Here using single-molecule imaging of division proteins in the Gram

151 Live, single-molecule imaging of endogenously tagged Unc13 rev

152 Single-molecule imaging of endosomal trafficking will si

153 Single-molecule imaging of fluorescently labeled biomole

154 In sum, real-time single-molecule imaging of fluorescently labeled Ebola V

155 Our single-molecule imaging of genome-editing proteins revea

156 Moreover, single-molecule imaging of green fluorescent protein (GF

157 e molecular details of deactivation, we used single-molecule imaging of green fluorescent protein (GF

158 g currently available XFELs and suggest that single-molecule imaging of individual biomolecules could

159 Here, we combine theoretical modelling with single-molecule imaging of live bacterial cells to show

160 harnessed to study molecular interactions in single-molecule imaging of live cells.

161 Using these ligands, we achieved single-molecule imaging of mu-ORs on the surface of livi

162 Here, we report single-molecule imaging of nascent peptides (SINAPS) to

163 lso compares favorably to what we measure by single-molecule imaging of nonspecifically bound fluores

164 chnology has wide applications for real-time single-molecule imaging of protein-nucleic acid interact

165 Using live-cell confocal and single-molecule imaging of rat hippocampal neurons cultu

166 Quantitative single-molecule imaging of receptor assembly in the plas

167 Using single-molecule imaging of reconstituted human DNA repai

168 y; 2) far-Western blotting; and 3) live cell single-molecule imaging of SH2 membrane recruitment.

169 so demonstrate the possibility of dual-color single-molecule imaging of SNAP-tag fusion proteins.

170 selection of optimal dyes and conditions for single-molecule imaging of SNAP-tagged fusion proteins i

171 Here we used live-cell single-molecule imaging of the divisome transpeptidase P

172 Using single-molecule imaging of the key proteins in vitro, we

173 Single-molecule imaging of translation in individual gra

174 of detyrosinated MTs in real time and employ single-molecule imaging of VASH1 bound to its regulatory

175 Single-molecule imaging offers a promising approach to a

176 immobilized cargo molecules, as revealed by single-molecule imaging on polymer-supported membranes.

177 d DNA structures promoted by TRF2-TIN2 using single-molecule imaging platforms, including tracking of

178 such as UCNPs with exceptional brightness at single molecule imaging powers.

179 ed upconversion nanoparticles are attractive single-molecule imaging probes due to their high photost

180 Single-molecule imaging provides a powerful way to study

181 specific adsorption on the interpretation of single-molecule imaging results.

182 Single-molecule imaging revealed key differences in the

183 Strikingly, live-cell, single-molecule imaging revealed that cohesin depletion

184 cipitation followed by mass spectrometry and single-molecule imaging revealed that this Gas5 isoform,

185 Single-molecule imaging revealed that unlike WASP/N-WASP

186 Additionally, live-cell single-molecule imaging revealed the constitutive intera

187 In one sample, CosMx single molecule imaging reveals subclones differentially

188 Single molecule imaging reveals that motors pause and fr

189 Single-molecule imaging reveals that AcrIIA11 hinders Sa

190 In vitro single-molecule imaging reveals that after actin nucleat

191 Single-molecule imaging reveals that GINS does not disso

192 Single-molecule imaging reveals that microtubule-bound a

193 Single-molecule imaging reveals that signaling is initia

194 Quantitative single-cell and single-molecule imaging reveals that the oncogenic TF EW

195 Solution assays and single-molecule imaging show that CAH3 binds CP already

196 Here, single-molecule imaging shows that all isoforms of apoE

197 Single-molecule imaging shows that cohesin confines the

198 Single-molecule imaging shows that MCMs are physical bar

199 Single-molecule imaging shows that msp300 is associated

200 Single-molecule imaging shows that this step lowers tran

201 l/noise in other techniques such as in vitro single-molecule imaging, stochastic optical reconstructi

202 Prospects and limitations of current single molecule imaging studies on nanoconfinement are a

203 (CaHydA), we now report electrochemical and single-molecule imaging studies carried out on a catalyt

204 of time-dependent conformation, all previous single-molecule imaging studies of polymer transport inv

205 Here we report live-cell single-molecule imaging studies of the kinetic features

206 Using a high-throughput single molecule imaging system and Lagrangian coordinate

207 This single-molecule imaging system with nanoscale resolution

208 bound to a glass surface and detected with a single-molecule imaging system.

209 A high-speed high-throughput single-molecule imaging technique for identifying molecu

210 sposon R-loops were observed by applying the single-molecule imaging technique of atomic force micros

211 These results suggest that the single-molecule imaging technique provides a powerful to

212 We have developed a single-molecule imaging technique that uses quantum-dot-

213 vity were measured using bulk solution and a single-molecule imaging technique to investigate the oli

214 single-molecule augmented capture (SMAC), a single-molecule imaging technique to quantify and charac

215 Single molecule imaging techniques at the atomic scale h

216 In the present study, we have used single molecule imaging techniques to demonstrate that T

217 Single-molecule imaging techniques have provided unprece

218 Single-molecule imaging techniques in live cells demonst

219 Here, we use single-molecule imaging techniques to directly measure t

220 In this work, we use single-molecule imaging techniques to examine the initia

221 MERFISH extends single-molecule imaging techniques to profile the copy n

222 Here, we use single-molecule imaging techniques to resolve the spatia

223 Here, we report the use of single-molecule imaging techniques to study the interact

224 a better exploitation of currently available single-molecule imaging techniques, provides an avenue t

225 Using single-molecule imaging techniques, we provide evidence

226 Here we present an ultrasensitive single-molecule imaging technology capable of detecting

227 Using in vitro single-molecule imaging technology, we directly observed

228 wards the ultimate goal of atomic resolution single-molecule imaging that is a prominent justificatio

229 y, our laboratory tests had shown that using single-molecule imaging that shear stress can extend sur

230 Here we applied a battery of single-molecule imaging, theory, and simulations to inve

231 expression assay uses molecular barcodes and single molecule imaging to detect and count hundreds of

232 Here we use single molecule imaging to examine BCR movement during s

233 We used single molecule imaging to measure tubulin turnover in s

234 s extracted from brain regions combined with single molecule imaging to monitor how an animal's physi

235 e employ genetics, cell lineage tracing, and single molecule imaging to show that mutations in lin-22

236 Here we use single-molecule imaging to count the number of RNA molec

237 We applied high-throughput single-molecule imaging to decode combinatorial modifica

238 Here, we use single-molecule imaging to demonstrate that BLM mediates

239 Here, we use single-molecule imaging to demonstrate that Rad54, a con

240 We used single-molecule imaging to demonstrate that Saccharomyce

241 We use single-molecule imaging to detect individual damage site

242 Here, we use real-time single-molecule imaging to determine how the ATP-depende

243 Here, we use in vitro single-molecule imaging to directly visualize DNA loop e

244 Here, we use single-molecule imaging to directly visualize Saccharomy

245 To elucidate this coordination, we used single-molecule imaging to follow the behaviours of the

246 ral mechanistic question, this study employs single-molecule imaging to investigate PI3K activation i

247 Here we used single-molecule imaging to investigate the effects of te

248 Here, we employed single-molecule imaging to investigate the mechanism of

249 To address this discrepancy, we applied single-molecule imaging to locate and track type 1 IP3Rs

250 ere we used DNA curtains in conjunction with single-molecule imaging to measure and quantify the bind

251 facilitated dissociation (FD), we have used single-molecule imaging to measure dissociation kinetics

252 Here, we use single-molecule imaging to measure the transition dipole

253 approach is presented for the application of single-molecule imaging to membrane receptors through th

254 tal internal reflection (TIR) microscopy and single-molecule imaging to monitor interactions between

255 Here, we utilized CRISPR genome editing and single-molecule imaging to monitor RTEL1 movement within

256 ome editing, super-resolution, and live-cell single-molecule imaging to probe subcellular composition

257 Here, we use single-molecule imaging to provide a quantitative mechan

258 ther, our studies demonstrate the utility of single-molecule imaging to provide mechanistic insights

259 Ticau et al. use single-molecule imaging to reveal how ORC, Cdc6, and Cdt

260 Here, we use single-molecule imaging to reveal that the Saccharomyces

261 Here, we used single-molecule imaging to show that cohesin can diffuse

262 Here, we used single-molecule imaging to show that the recombinant hum

263 We used single-molecule imaging to track quantum dot-labeled P2X

264 Here, we use CRISPR genome editing and single-molecule imaging to track telomerase trafficking

265 Here, we employed live-cell, single-molecule imaging to visualize and track fluoresce

266 Here, we use single-molecule imaging to visualize Cascade and Cas3 bi

267 locases act in crowded environments, we used single-molecule imaging to visualize FtsK in real time a

268 Here, we use single-molecule imaging to visualize Rad51 as it aligns

269 Here, we use single-molecule imaging to visualize Sgs1-dependent end

270 Here, we use single-molecule imaging to visualize the interplay betwe

271 We use single-molecule imaging to visualize the movement of ind

272 Here we have used multiple single molecule imaging tools to determine that the prot

273 Here, we combine in vivo and in vitro single-molecule imaging, transcription factor (TF) mutag

274 In summary, single-molecule imaging unveils the life cycle of telome

275 ties can be fundamentally improved by direct single-molecule imaging using regular epifluorescence mi

276 However, using single-molecule imaging we find that CTCF binds chromati

277 Using two-colour, single-molecule imaging we visualize interactions betwee

278 To achieve a signal/noise ratio conducive to single-molecule imaging, we adapted reflected light-shee

279 Using single-molecule imaging, we demonstrate that both conden

280 Using a reconstitution approach and single-molecule imaging, we demonstrate that nucleosomal

281 Here, using live-cell single-molecule imaging, we demonstrate that secretome m

282 Here, using single-molecule imaging, we demonstrate that the germ ce

283 Using genetics and single-molecule imaging, we demonstrate that this symmet

284 Using single-molecule imaging, we directly observe that the mi

285 Using biochemistry analyses and single-molecule imaging, we establish that RAD51 forms a

286 Using single-molecule imaging, we found that bacterial RecA an

287 Using live-cell and single-molecule imaging, we found that G118E mutation al

288 ing in vitro reconstitution biochemistry and single-molecule imaging, we found that HIV-1 binds to th

289 Using single-molecule imaging, we further show that uncoating

290 Using cryo-electron microscopy and single-molecule imaging, we investigated how MAP7 binds

291 Here, using single-molecule imaging, we measured the spatial distrib

292 Using single-molecule imaging, we present evidence that KIF1A

293 imple coculture experimental model and using single-molecule imaging, we provide quantitative data sh

294 re, using microfluidics-assisted three-color single-molecule imaging, we reveal that cyclase-associat

295 Here, using single-molecule imaging, we show that D2-I is a sliding

296 By next integrating spectrally resolved single-molecule imaging, we show that this localized dif

297 Using single-molecule imaging, we show that TubRC complexes we

298 Using microfluidics with single-molecule imaging, we simultaneously monitored rev

299 e we demonstrate the concept of submolecular single-molecule imaging with DNA chains assembled from D

300 Here we used single-molecule imaging with simultaneous whole-cell vol