ライフサイエンスコーパス: skewing

1 ated AD responses, with increased TH17/IL-23 skewing.

2 -146a was required to prevent overt Th1/Th17 skewing.

3 educed T cell numbers/proliferation, and TH1 skewing.

4 T cell lymphopenia and unusual T helper cell skewing.

5 ourth: inappropriate T-helper 2 (Th2) immune skewing.

6 ation was sustained, leading to enhanced Th2 skewing.

7 s, can directly activate DCs to induce T(H)2 skewing.

8 ing CD8 T cells, and CXCL10 antagonizes this skewing.

9 lated genes, largely lacking significant Th1-skewing.

10 the KAI2/MAX2 complex in the context of root skewing.

11 in sperm function associated with sex ratio skewing.

12 is that they are present and can affect root skewing.

13 g ability and consequently lead to sex ratio skewing.

14 ndicating the lack of requirement for clonal skewing.

15 ed HSCs presenting with a pronounced lineage skewing, a hallmark of HSC ageing.

16 al appearance, transcriptional profiling, Ab skewing, Ab repertoire, and secretory response to stimul

17 ic cDCs from NP-exposed mice have potent Th2-skewing ability and secrete increased levels of IL-6 and

18 tor of transcription 3 (Stat3) in T cells in skewing adaptive immunity in visceral adipose tissue (VA

19 ral strategy for the rational design of Th17-skewing adjuvants by combining agonists of the CARD9 pat

20 In addition, Th-skewing after GP-based immunization was altered in C3(-/

21 lopment in vivo, but this unexpected lineage skewing also highlights the importance of adequate spati

22 e results strongly suggest selection-induced skewing alters B-1a cell-derived natural Ab, which may i

23 FN-gamma, OASL, and T(H)2/IL-4 receptor/IL-5 skewing, although less than seen in patients with AD (al

24 atistically significant degree of positional skewing among epitopes; epitopes from both ends of antig

25 echanical development, including biased root skewing, an inability to penetrate hard agar layers, and

26 responses and protected against their T(H)1 skewing and apoptosis.

27 ence through the induction of laccase, a Th2-skewing and CNS tropic factor.

28 el finding on the direct association of Th17 skewing and disease severity illustrates the significanc

29 ding augmented specific IgG4 antibodies, Th1 skewing and enhanced IL-10.

30 New concepts on how T-cell skewing and epitope specificity are shaped by multiple e

31 r, concomitant with a peripheral Th2 profile skewing and ex vivo recipient hyporesponsiveness toward

32 ation, which massively reduced T-cell subset skewing and exhaustion.

33 endently promoted proinflammatory macrophage skewing and increased dendritic cell activation in the t

34 t mice, we found that S6K2 loss reduces Th17 skewing and increases regulatory T cell differentiation

35 s prestimulation thresholds for inflammatory skewing and NF-kappaB amplification in macrophages and f

36 e has immunomodulatory effects including Th2 skewing and reduced IL-10-secreting T regulatory cells,

37 orted by frequent B cell receptor repertoire skewing and stereotypy.

38 ind strong evidence of progressive rightward skewing and tail-fattening over time.

39 to mimic the effects of IL-6 on both Th1/Th2 skewing and Tfh cell differentiation.

40 These studies revealed repertoire skewing and the presence of high-frequency clonotypes th

41 filtrating lymphocytes showed TCR repertoire skewing and upregulation of CD137.

42 ed increased T-cell activation, naive T-cell skewing, and elevated serum CXCL9 and CXCL10 levels.

43 em cell (HSC) self-renewal capacity, myeloid skewing, and immune cell depletion.

44 une signaling, complement dysregulation, Th2 skewing, and increased secretion of MCP-1.

45 ficant chronic immune activation, phenotypic skewing, and inflammation driven by years of continuous

46 mportant pathway in T-cell proliferation, Th skewing, and inflammatory autoimmunity, and may be an at

47 plate, correcting for recombination, allelic skewing, and misincorporation/sequencing errors.

48 Many proteins are involved in root skewing, and we investigated the link between MAX2 and t

49 ed and is not due to underlying cytoskeletal skewing, as is the case in other known, phenotypically s

50 Ex vivo Th17 skewing assays demonstrate that genetic or pharmacologic

51 Skewing away from these conserved regions of the epitope

52 formation, Iglambda(+) and Igkappa(+) B cell skewing, B1/B2 development, and the initial extrafollicu

53 autologous lymphocytes, led to Th1 response skewing, based on significantly higher levels of IFN-gam

54 of both genes correlated with X-inactivation skewing but no significant association with age-adjusted

55 supernatants were sufficient to promote Th17 skewing, but those from Treg-mast cell cultures were not

56 indings counter previous hypotheses that Th2 skewing by DCs is a passive response and support a model

57 This skewing came at the expense of the number of lymphoid-pr

58 Since neonatal Th2 skewing can be modified by stimulation with Toll-like re

59 se of substance P to induce migration of Th2-skewing CD301b(+) DC to draining lymph nodes.

60 n rejection, establishing organ tolerance by skewing CD4 T helper polarization away from a proinflamm

61 udy highlights a role for these receptors in skewing CD8 T cell differentiation into effector and mem

62 In human TH1- or TH2-skewing cell culture systems, cotranscriptional R-loops

63 ecomes activated in mouse T cells under Th17 skewing conditions and phosphorylates interferon regulat

64 on of these effector-derived cells under Th1-skewing conditions leads to production of IFN-gamma alon

65 IL-13 production when cultured under type 1-skewing conditions, but maintained adequate levels of in

66 When placed under Th17-skewing conditions, CD4(+) T cells from fyn(-/-) mice ha

67 IL21, IL22, IL23R, RORC, and CSF2) under TH1-skewing conditions, suggesting a role for WASp in modula

68 In contrast, under Treg cell-skewing conditions, TEAD1 expression and sequestration o

69 After T cell activation under Tr1-skewing conditions, the AhR bound to c-Maf and promoted

70 and TH2 cells under respective TH1- and TH2-skewing conditions.

71 Treg skewing confers activated Teff phenotypic and functional

72 severe hyperinflammatory disease exhibit TCR skewing consistent with superantigen activation.

73 Follicular skewing correlated with IgA deficiency-associated endoto

74 umbers, TH2 cytokines were detected, and TH2 skewing correlated with total IgE levels.

75 Centric-skewing correlates with a bias towards class I binding p

76 or CD4 IL-2 production and subsequent immune skewing could contribute to lupus susceptibility in huma

77 may respond negatively to the UAVs, thereby skewing counts.

78 hancer, alters how DCs metabolize glutamate, skewing cytokine secretion to bias T cell function.

79 required to suppress expression of the Th17-skewing cytokines IL-6 and IL-23p19.

80 with production of proinflammatory and TH17-skewing cytokines, resulting in a TH17 immune response w

81 MPK signaling cascade, leading to macrophage skewing, dampening of inflammation, and regeneration of

82 , linking exposure to activation of allergic-skewing DCs and the initiation of an allergic immune res

83 during chorioamnionitis could be pivotal in skewing decidual monocyte differentiation to macrophages

84 optosis of CD8(+) T cells and are capable of skewing differentiation of macrophages into insulin-sens

85 tory response or increased T cell activation/skewing display a more impaired behavioral profile than

86 2B) and 5HT(7) receptors mediated the pro-M2 skewing effect of 5HT.

87 her these actions are related to its lineage skewing effects are poorly understood.

88 to PI may include specific IgE, Th2 cytokine skewing, eosinophils, activation of the complement, and

89 al a role for NADPH oxidase and p40(phox) in skewing epitope selection and T cell recognition of self

90 In vitro Th1/Th17-skewing experiments excluded the intrinsic effect of gal

91 ore, showing that it can produce evaluations skewing far from intuitive expectations.

92 g-specific events while avoiding the extreme skewing frequently seen in purely monoclonal systems.

93 3, can induce maturation and T-helper type 1 skewing function in human Langerhans cell-like dendritic

94 , fueled by complement imbalance and therapy-skewing genetic variance, underscore the need for more c

95 Skewing human antibody repertoires to target more conser

96 e in animals models of autoimmunity and Th17-skewing human cell culture in vitro.

97 with the expression of CD56, indicative for skewing human pDCs toward an interferon-producing killer

98 nd TH22 (IL-22 and S100As) axes and some TH1 skewing (IFN-gamma and CXCL10) were present.

99 Furthermore, the production of TH17-skewing IL-6, IL-23, and TNF-alpha by dendritic cells in

100 3), but AD tissues showed preferential T(H)2 skewing (IL-13, CCL17/TARC, and CCL18), whereas psoriasi

101 ell malignancy characterized by Th2 cytokine skewing, impaired T-cell responses, and overexpression o

102 ived butenolides), caused alteration in root skewing in Arabidopsis thaliana.

103 There was skewing in favor of memory T cells and intense autoantib

104 om escape from XCI and from mosaicism or XCI skewing in females.

105 cent studies have uncovered T helper type 17 skewing in ichthyotic skin, resembling psoriasis, and hi

106 The 1,25D-triggered skewing in ILC3 function was not accompanied or caused b

107 R1/2, reduced Treg function and induced Th17 skewing in MS patient samples more than in healthy contr

108 Blood phenotyping shows only TH2 skewing in patients with early-onset pediatric AD, but a

109 We connect this fate selection to skewing in production of hepatocyte growth factor (HGF)

110 We also observed a skewing in the balance between proinflammatory and regul

111 Cytokine responses showed trends towards Th1 skewing in the GI-homing alpha4beta7+ cells of peanut-to

112 essing human MCL1 as a transgene exhibited a skewing in the proportion of CD8(+) T cells, away from S

113 ta7+ cells of peanut-tolerant groups and Th2 skewing in the skin-homing CLA+ cells of peanut allergic

114 more suppressive, and were resistant to Th17 skewing in vitro.

115 of urothelial hyper-diploidy and cell cycle skewing in wild-type but not Il4ra(-/-) mice.

116 was initially observed through an increased skewing in X-chromosome inactivation [1].

117 r, for some mouse genes, there appears to be skewing, in some ways resembling skewed X-inactivation,

118 Although T(H)1/T(H)17 skewing increases in both patients with AD and control s

119 This skewing is mediated by the recruitment by IL-4Ralpha(R57

120 e underlying potential energy landscape, and skewing it in favor of the unloaded side, and in some si

121 aturation within the tumor microenvironment, skewing it toward a Th2 immune response and impairing CD

122 While HDM caused significant Th2 skewing, it also illustrated differences in Th2 inductio

123 Monocyte M2 skewing likely contributes to NO bioinsufficiency in fal

124 In addition, 4-fold expansion and skewing (lower T1/T2-ratio) of the immature B cell subse

125 LCN2 induced IL-10 formation by macrophages, skewing macrophage polarization in a STAT3-dependent man

126 ed that iron promotes differentiation, while skewing macrophages toward a hypersecretory M2-like pola

127 This IRA B cell-dependent T helper-1 skewing manifests in an IgG1-to-IgG2c isotype switch in

128 (MPhi) antibacterial effector mechanisms by skewing MPhis toward an alternatively activated M2 pheno

129 esis, and the Foxn1 BM niche may function in skewing MPP development toward T lineage progenitors.

130 tion and suggest that PD-1 may contribute to skewing NK cells toward enhanced ADCC during infections

131 For carriers with extreme XCI skewing of 80:20 or more, 57% were affected severely com

132 Skewing of allergen-specific effector T and effector B c

133 on against antigenically variable viruses is skewing of antibody responses to variable immunodominant

134 in HIV-infected individuals, focusing on the skewing of B-cell subsets that circulate in the peripher

135 mic autoimmune disease, displayed a profound skewing of blood CXCR5(+) Th cell subsets toward Th2 and

136 in EPC/CAC apoptosis, and by preventing the skewing of CACs toward nonangiogenic pathways.

137 Skewing of CD4(+) T cell differentiation toward Ag-speci

138 Le(X)-modification of OVA favored Th1 skewing of CD4(+) T cells and enhanced cross-priming of

139 rculating T, B, and NK cells and exhibited a skewing of CD8+ T cells toward a terminally differentiat

140 ion of normal T-cell proliferation and a Th2 skewing of cytokine production.

141 amma expression, poor help for CD8 CTLs, and skewing of DC subsets toward plasmacytoid DCs, coupled w

142 IFN-gamma expression, help for CD8 CTLs, and skewing of dendritic cell (DC) subsets toward CD8a DCs,

143 genome-wide survey of the degree of allelic skewing of DNA methylation with the aim of identifying p

144 terized by defective CD4 cell proliferation, skewing of effector CD4 T cells from a Th1 to a Th17 phe

145 PM3-myopathy, and is commonly accompanied by skewing of fibre-type ratios (either slow or fast fibre

146 Lastly, clonal skewing of hematopoiesis was detected in 67% of young, a

147 w consistent with a retinoid-induced myeloid skewing of hematopoiesis.

148 Moreover, pronounced skewing of Iglambda/Igkappa ratio was evident among TIL-

149 ed expression of activation markers, and the skewing of immune cells within the tumor toward an macro

150 A skewing of immune responses toward Th2 in transplant pat

151 showed that Ssa1 directly promotes early M2 skewing of lung mononuclear phagocytes during the innate

152 The preferential proinflammatory skewing of M16 relative to M14 was found to be mediated

153 cle promotes recruitment, proliferation, and skewing of macrophages toward a cyto-destructive phenoty

154 blems that would otherwise contribute to the skewing of mass assignments and reduction of S/N.

155 Indeed, a skewing of megakaryocyte commitment and differentiation

156 reatment, a dramatic reduction of TIMs and a skewing of MHCII(low) to MHCII(hi) macrophages were obse

157 Functional skewing of mononuclear phagocytes occurs in vivo under p

158 Immunoregulatory skewing of mucosal Th17 cell function, characterized by

159 oiesis, and granulomonocytic differentiation skewing of multipotent and common myeloid progenitors.

160 Chronic skewing of myeloid production occurred in parallel to a

161 r stress conditions, including an adipocytic skewing of perivascular cells.

162 ommitment, supported functionally by myeloid skewing of progenitors following treatment with a DNA me

163 Limitations included artifactual skewing of quantification by mass bias, a limited mass r

164 AR1 knock-out mice occurred in tandem with a skewing of reactive astrocyte signatures toward a prorep

165 une correlates of allergy protection include skewing of regulatory over effector T cells, expansion o

166 mice resulted in the aggravation of NTN and skewing of renal and systemic immune responses toward Th

167 Although skewing of responses toward primary infecting viruses wa

168 Importantly, the skewing of subsets correlated with disease activity and

169 Further, HIV exposure led to skewing of T cell phenotypes predominantly to inflammato

170 The skewing of T-cell differentiation is concomitant with ch

171 ording to the original antigenic sin theory, skewing of T-cell responses induced by primary infection

172 Clonality and skewing of TCR repertoires were associated with interfer

173 cognition it mediates cytokine responses and skewing of the adaptive immune system.

174 hanced allograft survival and protolerogenic skewing of the alloresponse is critically dependent on c

175 ences showed a secular trend toward positive skewing of the BMI distribution at younger ages.

176 at the Igkappa locus that showed a dramatic skewing of the expressed Igkappa repertoire.

177 f the hematopoietic stem cell, even a slight skewing of the fraction of cells that differentiate woul

178 Skewing of the human oral microbiome causes dysbiosis an

179 ophage invasion into biofilms in vivo, and a skewing of the immune response away from a microbicidal

180 infiltration of immune cells as well as the skewing of the immune response toward a Th2 cytokine pro

181 Skewing of the immunoglobulin heavy variable (IGHV) gene

182 in autoimmune diseases is associated with a skewing of the immunometabolic programs.

183 iatic skin and that risk carriers manifest a skewing of the inflammatory network toward stronger IFN-

184 ed two hallmarks of MHC-dependent education: skewing of the Ly49 receptor repertoire and differential

185 These changes indicate a skewing of the memory population toward the central memo

186 n BM and spleen were increased, suggesting a skewing of the OC precursors toward DC differentiation.

187 as accelerated concomitantly with a dramatic skewing of the proportion of pStat5-expressing cells rel

188 a desirable broad antibody response, without skewing of the response toward preferential recognition

189 hromosome inactivation may contribute to the skewing of the sex prevalence of parkinsonism toward wom

190 of T2 B cells, suggesting a link between the skewing of the T1/T2 ratio and the formation of immune c

191 These results depict a skewing of the TIGIT/CD226 axis from CD226 co-stimulatio

192 lar artery geometry strongly influenced both skewing of the velocity profiles and the wall shear stre

193 tivation and excessive T-helper type 1 (Th1) skewing of Treg cells into Th1-like Treg cells.

194 majority of MLS-affected females have severe skewing of X chromosome inactivation, suggesting that mu

195 We investigated the effect of Treg skewing on the phenotypic and functional properties of C

196 gamma production by CD4 T cells and not to a skewing or expansion of Th2 or regulatory T cells.

197 s via ITAM-based calcium signaling pathways, skewing osteoclast metabolism toward oxidative phosphory

198 covering from past disturbances, potentially skewing our interpretations of forest dynamics and our u

199 ipulations, Dnmt3a+/- mice developed myeloid skewing over time, and their hematopoietic stem/progenit

200 establishment of the aged-associated myeloid skewing phenotype, which may contribute to age-associate

201 evealed that Zbtb16(lu/lu)HSCs had a lineage-skewing potential from lymphopoiesis toward myelopoiesis

202 em cell (HSC) exhaustion and myeloid-lineage skewing promote oncogenic transformation of hematopoieti

203 SCs that occur in old age, including myeloid skewing, reduced reconstitution potential, impaired self

204 ction resulted into a pronounced immunologic skewing regarding the expansion of CD8(+) T cells in the

205 Our findings implicate public TCR in skewing repertoire response during autoimmunity and sugg

206 Skewing responses toward IgG(2) and IgG(4) subclasses mi

207 nd that PCR stochasticity is the major force skewing sequence representation after amplification of a

208 vated levels of c-di-GMP inhibit swarming by skewing stator selection in favor of the nonfunctional,

209 regulatory T cells showed marked oligoclonal skewing, suggesting that their peripheral expansion was

210 nerates concomitant changes to the proteome, skewing synthesis of newly synthesized proteins away fro

211 Skewing T cell differentiation toward a Th2-dominated ph

212 Finally, skewing T cell metabolism toward aerobic glycolysis by d

213 between inflammation and immune tolerance by skewing T-cell fate decisions toward either the T-helper

214 nction, apoptosis, T helper (Th)1 versus Th2 skewing, T cell receptor signaling, and MHC class II ant

215 iratory epithelial function, and immune cell skewing that are hallmarks of asthma.

216 state of activation results in B cell subset skewing that is likely the result of alterations in home

217 ivity (maximal velocity, Vmax), particularly skewing the balanced hydrolysis of isomers to favor the

218 iferating T cells, diminishing the yield and skewing the CD4/CD8 ratio in the T-cell population, jeop

219 ns such as ARVs can induce metabolic stress, skewing the cell's immune response and restricting (cell

220 and altered the T cell repertoire landscape, skewing the distribution of T cells toward lower-frequen

221 s, due to enigmatic physiological influences skewing the elemental record.

222 frequencies of CD127(+) NK cells in CR mice, skewing the function of the total NK cell pool.

223 Thymic stromal lymphopoietin, a cytokine skewing the immune response toward a Th2 direction, was

224 sion and during chronic obesity, permanently skewing the immune system to a proinflammatory phenotype

225 function in vivo exacerbates shigellosis by skewing the inflammatory cytokine response, disrupting c

226 (Mfge8), in directing cardiac remodeling by skewing the inflammatory response after myocardial infar

227 The total effect of OPN on skewing the leukocyte population balance was observed as

228 lection contributes to effective immunity by skewing the mature TCR repertoire toward highly effectiv

229 CD56(dim)CD57(+)NKG2C(+) NK cell population, skewing the NK cell repertoire in favor of cytotoxic res

230 ived growth factor receptor (PDGFR), thereby skewing the PI3K axis toward tumor cell proliferation.

231 e that nicotine promotes brain metastasis by skewing the polarity of M2 microglia, which enhances met

232 increase in the response magnitudes without skewing the quality.

233 (Tregs) and decreased numbers of Th17 cells skewing the ratio of Tregs to autoreactive effector T ce

234 by reducing species number (richness) and by skewing the relative abundance of species (evenness).

235 perienced the greatest DNA damage responses, skewing the response toward lower-affinity responders wi

236 Finally, skewing the response toward neutrophil-inducing lymphocy

237 elied on double-knockout models, potentially skewing the role of Bcl-2, and the use of Bcl-2 as a mar

238 cerbate the effects of viral reactivation on skewing the T cell repertoire in CMV-infected individual

239 of monocytes in microbial recognition and in skewing the T cell response towards Th17.

240 of monocytes in microbial recognition and in skewing the T-cell response toward Th17.

241 The overall effect is skewing the TAMs from M2-polarized TAMs into the M1-pola

242 nputs from both the Imd and Toll pathways by skewing the transcriptional output of the NF-kappaB dime

243 ll or DC lineages protected mice from AAI by skewing the typical TH2 immune response toward a TH1 res

244 TCR-mediated proliferation and Th1 and Th17 skewing, the former corresponding with an inability to s

245 innate and adaptive immune cell populations skewing their polarization toward a more tolerogenic ant

246 enhancing the overall magnitude but also by skewing this response to one that is dominated by IgG is

247 hat factors in the RCC microenvironment were skewing TIL phenotype toward EM.

248 dependent CLL patient cohorts, failed T-cell skewing to antigen-experienced subsets, decreased costim

249 MM cells also cause Th17 skewing to foreign Ag in normal mice without Th17-polari

250 changes in function and structure, including skewing to myeloid lineages, lower reconstitution potent

251 LOS biosynthetic genes indicated significant skewing to specific alleles, dependent on the disease ou

252 roid and lymphoid differentiation and strong skewing to the myeloid lineage, with only a mild relatio

253 p1-deficient CD4(+) T cells also resulted in skewing to the Th2 lineage and increased IL-4 production

254 ) as the extracellular trigger of macrophage skewing toward a pro-reparative phenotype.

255 ated CD8(+) T cells inhibit Ab production by skewing toward a proinflammatory cytokine profile, where

256 mmatory transcriptional programming, and (3) skewing toward a T helper (Th)/T cytotoxic (Tc)17 transc

257 ly naive T cells acquire a memory phenotype, skewing toward a T(EM) phenotype was prominent in the ab

258 CD4(+) T cells also demonstrate significant skewing toward a TH17 phenotype that is implicated in au

259 associated with increased CD4+ T cells, with skewing toward a Treg- and Th2-dominated phenotype, sugg

260 d by enhanced clearance by macrophages and a skewing toward an M2 phenotype.

261 In these animals, a preferential skewing toward CD4 repopulation and proliferation was ob

262 ) and CD8(+) cellular immune responses, with skewing toward CD4(+) T-cell activity against MARV GP.

263 Interestingly, gp140 boost induced a skewing toward CXCR3 expression on germinal center TFH c

264 of the ALAS2 mutation, there was a complete skewing toward expression of the WT allele in mRNA from

265 s is required for myeloid progenitor lineage skewing toward granulocyte-macrophage progenitors, incre

266 ve transfer into NOD.Rag recipients due to a skewing toward impaired Treg suppression.

267 issue (AT) MPhi abundance was increased with skewing toward M1 polarization.

268 fivefold in Runx1 KO mice, with a prominent skewing toward megakaryocyte (Meg) progenitors.

269 , there was a weaker effector response and a skewing toward memory precursor cells.

270 apacity with an altered cell differentiation skewing toward monocytic/granulocytic lineages.

271 Skewing toward myeloid cell production is often observed

272 olution and decreased lymphoid output with a skewing toward myeloid development, and increased memory

273 ch as the increase in number of HSCs and the skewing toward myeloid-biased HSCs during aging.

274 ow considerable heterogeneity of N-ERD, with skewing toward T2 response and eosinophilic inflammation

275 Our findings provide evidence that T-cell skewing toward TEM may be associated with antigraft reac

276 ice, lacking Treg1 cells, showed spontaneous skewing toward Th1 immunity.

277 ntiation and exhaustion as well as increased skewing toward Th17 cells.

278 Instead, they show skewing toward TH2 responses, which, together with immun

279 ors have been shown to reprogram the marrow, skewing toward the expansion of myelopoiesis.

280 ive VDJ rearrangement, there was significant skewing toward the incorporation of proximal VH gene seg

281 Phenotypic and transcriptional skewing toward the memory fate was observed during the C

282 nd adapt through increased proliferation and skewing toward the myeloid lineage.

283 ockout (DKO) iNKT cells displayed pronounced skewing toward the NKT17 lineage, with increased DNA met

284 e while maintaining higher IP-10 production, skewing toward the type I interferon pathway.

285 he T cell-to-MDSC balance, associated with a skewing toward type 2 immunity, may predict bladder tumo

286 l translocation and natural killer (NK) cell skewing towards an inflammatory state, with chromatin st

287 s we observe global hypomethylation but with skewing towards hypermethylation when interrogating gene

288 oxp3(+) and CD4(+)Foxp3(-) cells show strong skewing towards Tfh/Th17 phenotypes.

289 that include a decline in lymphopoiesis and skewing towards the myeloid lineage.

290 that Act-A-iTreg cells dampened crucial TH2-skewing transcriptional networks in DCs.

291 tion at these upstream sites, differentially skewing translation and protein expression.

292 atures suppress endogenous immune responses, skewing tumor growth data and the severity of graft vers

293 This skewing was associated with oligoclonality and restricte

294 This myeloid skewing was cell intrinsic, as arthritic HSPPCs up-regul

295 Most important, Th17 skewing was prominent in advanced PBC patients with inte

296 Th2 skewing was seen in both ADFM and ADWT, with no differen

297 mics as a key mediator of CTRA transcriptome skewing, which may both propagate perceived social isola

298 a therefore, KAI2 and MAX2 act to limit root skewing, while kai2's gravitropic and mechano-sensing re

299 kdown of Lin28A led to hematopoietic lineage-skewing, with increased myeloid and decreased B-cell num

300 the hematopoietic compartment shows lineage-skewing, with myeloid cell numbers dramatically increase