ライフサイエンスコーパス: skinned fiber

1 eration and rate of tension redevelopment in skinned fibers.

2 red abilities to inhibit ATPase and to relax skinned fibers.

3 osin complex in myofibrils and in chemically skinned fibers.

4 nC (cardiac and slow skeletal troponin C) in skinned fibers.

5 3% decrease in maximum developed force), and skinned fibers (14% decrease in maximally activated forc

6 mbinant HCTnTs was incorporated into porcine skinned fibers along with human cardiac troponin I (HCTn

7 We analyze control skinned fibers and fibers subjected to myosin extraction

8 related with increased Ca(2+) sensitivity in skinned fibers and vice versa.

9 and structural role of the RLC in chemically skinned fibers at various thick and thin filament lattic

10 depression in tension and ATPase activity in skinned fiber bundles from a TG model in which cTnI is r

11 of tension and ATPase activity of detergent-skinned fiber bundles from left ventricular papillary mu

12 Exchange of cTnI in skinned fiber bundles with cTnI(146G) induced enhanced C

13 tension development in detergent-extracted (skinned) fiber bundles isolated from mouse left ventricu

14 cross-bridge cycling kinetics as measured in skinned fibers derived from the diseased muscle.

15 Porcine papillary skinned fibers displaced with HSSTnT1, -2, or -3 and rec

16 In troponin-exchanged skinned fibers, each mutant caused a significant increas

17 with severe mitochondrial damage, and their skinned fibers failed to activate with calcium.

18 with nonischemic control hearts, bundles of skinned fibers from hearts subjected to ischemia alone d

19 Single, skinned fibers from rabbit psoas muscle were used to tes

20 amidotetramethylrhodamine and exchanged into skinned fibers from rabbit psoas muscle without signific

21 ric tension over a wide range of [Ca(2+)] in skinned fibers from rabbit psoas muscle.

22 C-5'ATR), in sTnC-5'ATR reconstituted single skinned fibers from rabbit psoas muscle.

23 exchanged for the endogenous RLC in single, skinned fibers from rabbit psoas muscle.

24 influence in intact hearts, trabeculae, and skinned fibers from wild-type (+/+) and homozygous trunc

25 In skinned fibers, I79N increased myofilamental calcium sen

26 Ca(2+) sensitivity of contraction in skinned fibers increased with mutant gene dose: KI-TnC-A

27 ction in elastic modulus in Dmlc2(Delta2-46) skinned fibers is consistent with the N-terminal extensi

28 ps) of 3-7 degrees C were examined in single skinned fibers isolated from rabbit psoas (fast) and sol

29 Surprisingly when the kinetics of skinned fibers isolated from the ELC1vDelta5-14 or ELC1a

30 Investigation of cardiac skinned fibers isolated from WT and heterozygous mice re

31 While skinned fibers offer the advantage of preserving the nat

32 ated hearts, isolated papillary muscles, and skinned fiber preparations), biochemical and molecular b

33 oncentration (Vmax) have been assessed using skinned fibers prepared from two oxidative muscles (vent

34 lopment of cardiac disease include increased skinned fiber sensitivity to calcium and, at the whole o

35 roteins reconstituted into porcine papillary skinned fibers showed decreased Ca(2+) sensitivity of fo

36 that in matrixed tension assays using mouse skinned fibers showed diverse antagonist and desensitiza

37 ), were expressed, purified, and utilized in skinned fiber studies and in reconstituted actomyosin AT

38 ions in cTnI, actomyosin ATPase activity and skinned fiber studies were carried out.

39 In skinned fiber studies, TnT1-wild-type (WT)-treated fiber

40 The skinned fibers study revealed no change in myofilament k

41 both the Ca(2+) binding measurements and the skinned fiber tension measurements, the presence of cTnI

42 In maximally activated skinned fibers, the rate of tension redevelopment (ktr)

43 Exposure of skinned fiber to caspase-3 decreased maximal Ca(2+)-acti

44 e/decrease the Ca(2+) sensitivity of cardiac skinned fibers to create the characteristic effects of D

45 spacing of dissected, osmotically compressed skinned fibers to native muscle fibers in living flies.

46 ociated with increased Ca(2+) sensitivity in skinned fibers was identified; and 3) the F27W reporter

47 The maximal force in reconstituted skinned fibers was significantly greater for the cTnT1 (

48 ot other contractile proteins in "chemically skinned" fibers, we substantially reduced the contractil

49 Skinned fibers were maximally Ca(2+)-activated at 20 deg

50 TnC-extracted cardiac skinned fibers were reconstituted with the cTnC-A31S mut

51 Small step-stretches of single skinned fibers were used to study the effect of phosphor