ライフサイエンスコーパス: slowing

1 ctroencephalography showed generalized theta slowing.

2 of septate-like junctions and in conduction slowing.

3 ogression and promoting MRE11-dependent fork slowing.

4 rature dependence characteristic of critical slowing.

5 o expend effort for rewards; and psychomotor slowing.

6 at mild and strong depolarization pulses by slowing activation and enhancing inactivation, respectiv

7 n (MD) serves to regulate Hsp104 activity by slowing ADP release.

8 cell proliferation is an effective means of slowing ADPKD progression caused by inactivation of Pkd1

9 s, but the impact of this activity-dependent slowing (ADS) is unknown.

10 C fibers display activity-dependent slowing (ADS), whereby repetitive stimulation (>/=1 Hz)

11 d TGF-beta1 signaling axis holds promise for slowing age- and disease-related degeneration of NMJs.

12 rilesional) exhibit pathological oscillatory slowing and alterations in signal complexity.

13 Unlike conduction velocity slowing and APD heterogeneity, the magnitude of APD alte

14 ng, yet a direct relationship between neural slowing and brain atrophy is yet to be established in he

15 ted perceptual events-and they lead to motor slowing and cognitive distraction.

16 cient (Mpo(-/-)) mice showed less pronounced slowing and decreased heterogeneity of electric conducti

17 Significant heart rate slowing and frequent sinus pauses are observed in iNICD

18 ti-ion channel block, with significant sinus slowing and increased PR, QRS, QT, and QTc intervals, as

19 Doses of 40 and 55 Gy caused slowing and interruption of cardiac impulse propagation

20 h the correct order of magnitude, post-error slowing and post-error improvement in accuracy, two subt

21 suggesting fork remodeling as a global fork slowing and protection mechanism.

22 ble to a combination of DNA replication fork slowing and reduced replication origin firing.

23 led significant rate-dependent RA conduction slowing and rotor activity, including stable rotors in 4

24 Fork slowing and stalling occur at structurally distinct lesi

25 neuropathy, as indicated by nerve conduction slowing and thermal hyperalgesia.

26 AFDs; 21 AF termination and 33 cycle length slowing) and occurred in all 27 patients.

27 iour, including motor inhibition, decisional slowing, and value sensitivity.

28 Motor slowing appears in preclinical Alzheimer disease (AD), p

29 ese structures, which upend traditional wave-slowing approaches based on resonances or on periodic co

30 at remodeling processes promoting conduction slowing as opposed to APD prolongation mark the chronic

31 Cell cycle slowing as the embryo approaches the MBT permits increas

32 outflow and by measuring activity-dependent slowing at 2 Hz stimulation.

33 tal Panel on Climate Change projections of a slowing Atlantic meridional overturning circulation (MOC

34 of lever arm priming (recovery stroke) while slowing ATP hydrolysis, demonstrating that it uncouples

35 or domains in the microtubule-bound state by slowing ATP-binding, resulting in high-force production

36 disrupting Na(V)1.5-rich ID nanodomains and slowing atrial conduction.

37 ceptibility by disrupting ID nanodomains and slowing atrial conduction.

38 This indicates that R249Q myosin is slowing attachment while speeding up detachment from act

39 of therapies designed to prevent disease by slowing biological aging.

40 Conclusions Wavefronts of conduction slowing/block may aid identification of critical isthmus

41 ogical parameters associated with conduction slowing can cause block and re-entry in the BZ.

42 ch in cardiac sodium channels (Na(V)1.5) and slowing cardiac conduction.

43 g promotes adhesion to HA by both physically slowing cells and enabling them to position proximal to

44 composition may contribute to the cell-cycle slowing, changes in chromatin structure, and the onset o

45 including seven for CKD prevention, two for slowing CKD progression, two for CKD management, one for

46 rs the FokI catalytic domain with the aim of slowing cleavage, which should selectively reduce activi

47 for personalized therapeutic approaches for slowing clinical progression of AD.

48 en metabolism, photosynthesis and growth and slowing CO(2) release into the atmosphere.

49 veness of physical activity interventions in slowing cognitive decline and delaying the onset of cogn

50 pid initial rates of H2O2 disproportionation slowing concomitantly with the accumulation of ferryl-li

51 The faster phase of voltage-sensor return slowing correlated with the kinetics of pore opening.

52 sociation between slow oscillation and delta slowing could help localize the seizure onset zone from

53 alter voltage sensor-pore coupling, thereby slowing current deactivation.

54 ing the voltage dependence of activation and slowing deactivation, similar to perfusion of isoprotere

55 ementia risk by improving memory function or slowing decline.

56 income had the largest estimated benefit for slowing declines (for 10-year memory change, beta = 0.35

57 In compliment, we show that slowing detachment from this vulnerable state by strengt

58 This may be important in slowing disease progression and provides insight into th

59 E supports the continued efficacy of A1PI in slowing disease progression during 4 years of treatment.

60 s been suggested as a potential approach for slowing disease progression in ALS.

61 s are preceded by the phenomenon of critical slowing down (CSD).

62 This paper utilizes Critical Slowing Down (CSD; instability) indicators developed by

63 For instance, critical slowing down (declining rate of recovery from small pert

64 ational and experimental support of critical slowing down along natural stress gradients in tidal mar

65 Slowing down anaphase chromosome motion delayed Cyclin B

66 indicators of tipping points, like critical slowing down and flickering.

67 lts indicate that the phenomenon of critical slowing down can provide a powerful tool to probe the re

68 e barrier for the advance of the polymerase, slowing down DNA synthesis.

69 ofoundly impairs safety learning, abnormally slowing down fear extinction and exacerbating fear relap

70 The metrics used to detect critical slowing down fluctuated over temporally long scales (hou

71 Compensating for the metabolic imbalance by slowing down glycolysis, activating gluconeogenesis or d

72 We find critical slowing down in the data at the level of California and

73 us disordered materials display a monotonous slowing down in their internal dynamics with age.

74 retical models and demonstrate that critical slowing down is a reliable indicator that could be used

75 approach remembers old tasks by selectively slowing down learning on the weights important for those

76 Cells quickly responded to Cu(2+) stress by slowing down metabolism.

77 By slowing down microtubule dynamics, we reveal such a mech

78 her pro-inflammatory mediators, consequently slowing down muscle stem cell depletion.

79 disease type C (a neurodegenerative ataxia), slowing down neurodegeneration and increasing lifespan.

80 these results are symptomatic of a critical slowing down of chaos that sits at the root of our stati

81 ic/torpedo mechanism, in which PP1-dependent slowing down of polymerases over termination regions fac

82 eleconnections' we hypothesise that observed slowing down of sea surface temperature variability cont

83 atter physics: agreement on the cause of the slowing down of structural relaxation in glass-forming l

84 above the critical concentration lies in the slowing down of the cells, which enables them to sense l

85 y for correct nucleotide incorporation, 2) a slowing down of the replication rate after misincorporat

86 order of a few centimeters per second before slowing down on a longer time scale.

87 plasmonic tapers to generate hot carriers by slowing down plasmons at the taper apex.

88 psy, we monitored key signatures of critical slowing down prior to seizures.

89 incidence might not exhibit typical critical slowing down properties before a critical transition, th

90 cant activity and reveal the consequences of slowing down proton transfer for both catalytic directio

91 While slowing down reduces the chances of being detected from

92 lary to this spatial nutrient theory is that slowing down spatial nutrient pathways can be a potent m

93 hat Somatostatin 1.1 innately contributes to slowing down spontaneous locomotion.

94 Critical slowing down starts growing appreciably several years be

95 ncentration of 0.0125% (w/w of emulsion), by slowing down the formation of hydroperoxides and malondi

96 Specificity may be increased by slowing down the kinetics of regulation: by increasing t

97 votal role played by ferrotoroidic states in slowing down the magnetic relaxation, in spite of large

98 ns adopt two distinct states, with one-third slowing down the microtubule and two-thirds speeding it

99 interaction between NPs and substrate, thus slowing down the Ostwald ripening process during post-ox

100 that enhancing the accuracy should result in slowing down the process, leading to the so-called speed

101 e movement of ribosomes along mRNAs, thereby slowing down the rate of elongation.

102 on of D-amino acids into nascent proteins by slowing down the rate of peptide bond formation.

103 cacy and maintain it for 2 weeks effectively slowing down the rate of translation elongation.

104 ve:extruded banana starch composite (MB), in slowing down the starch digestibility of bread crumb and

105 ion, contrary to that expected from critical slowing down theory; this could lead to unreliable indic

106 a: see text] at the beginning and eventually slowing down to the diffusive spread [Formula: see text]

107 a relatively large number of photons, hence slowing down total acquisition times.

108 "expanding", "shrinking", "speeding up" and "slowing down" ecological processes and interactions, and

109 tical and laboratory studies, this 'critical slowing down' remains largely untested in the complex se

110 lk was red' or with 'the approaching car was slowing down'?

111 recorded brain signals may exhibit critical slowing down, a warning signal preceding many critical t

112 The recent progress, however, has been slowing down, and many important drug delivery problems

113 erent phenotypes can be captured by critical slowing down-based early-warning signals, calculated fro

114 n energy, a transient equivalent of critical slowing down.

115 s (EWSs) derived from the theory of critical slowing down.

116 Slowing-down GTP hydrolysis leads to extended GTP caps.

117 The effect of climate change on the slowing-down of SCA at MLO is mainly exerted by intensif

118 We found that slowing-down of SCA at MLO is primarily explained by res

119 nalyzed the potential driving factors of SCA slowing-down, with an ensemble of dynamic global vegetat

120 The current results demonstrate that slowing drug release in the mammary duct after intraduct

121 on extended toward the prey [2], with little slowing during prey impalement.

122 ds to a location characterized by activation slowing during sinus rhythm (SR).

123 However, the relationship between activation slowing during SR and vulnerability for reentry and corr

124 examined the relationship between activation slowing during SR and vulnerability for reentry and corr

125 Regions of maximal endocardial slowing during SR corresponded to the VT isthmus (area u

126 Endocardial activation slowing during SR may differentiate infarctions vulnerab

127 ith VT had a greater magnitude of activation slowing during SR.

128 to around 50% of normal; however, outside of slowing emphysema progression, its effects in other clin

129 ening surface lifetimes by pharmacologically slowing endocytosis was sufficient to increase arrestin-

130 ce, improving glucose tolerance and modestly slowing fat mass gain.

131 lerating actin filament assembly locally and slowing filament capping.

132 The common phenomena of slowing fitness increases during adaptations and diminis

133 lly accounts for the significant psychomotor slowing found in those with high BMI.

134 with Alzheimer disease and the difficulty in slowing functional decline.

135 C(60)/perovskite interface of full devices, slowing further hydrolysis reactions that would damage t

136 y Ca(v)3.1 channels as potential targets for slowing GBM progression and recurrence based on their ro

137 Consistent with conduction slowing, genes encoding molecular determinants of atrial

138 bow trapping is related to the progressively slowing group velocity, and the extremely low group velo

139 as defined as AF termination or cycle length slowing >=30 ms.

140 tibody specificities have been implicated in slowing HIV-1 disease progression and in protection.

141 Globally HIV incidence is slowing, however HIV epidemics among sex workers are sta

142 012) a very small but statistically reliable slowing in a single session of context fear conditioning

143 ptical mapping showed significant conduction slowing in AF+AFLs and AF but not AFL, paralleling atria

144 s, thermal hypoalgesia, and nerve conduction slowing in diverse rodent models of diabetes.

145 athletes, with discharge rates progressively slowing in females only.

146 sing marker for dopamine-related psychomotor slowing in geriatric neuropsychiatry.

147 Notably, OM induced a slowing in krel with 1.0 mumol/L OM but not with 0.5 mum

148 Baumard proposes that life history slowing in populations over time is the principal driver

149 based learning (P = 0.028) and (2) a general slowing in processing speed (P < 0.001) and a shift in p

150 Despite a modest slowing in response initiation across all task condition

151 emained unaffected, and ABA responses showed slowing in some experiments.

152 Functional conduction slowing in the BZ was modeled by reducing sodium current

153 on to thin filament Ca(2+) sensitization and slowing in the C-zone, we used a combination of in vitro

154 unexpected infant death has contributed to a slowing in the decline of these deaths.

155 videnced by a greater enhancement in Pdf and slowing in the time course of cooperative XB recruitment

156 Pathological MEG slowing in these patients was correlated with aphasia se

157 demands and might give rise to the apparent slowing in thinking and intermittent confusion which typ

158 Slowing is a common feature of ageing, yet a direct rela

159 We show that motor slowing is associated with a gradual increase of net exc

160 Here, we aim at testing whether this EEG slowing is linked to the pathological intrusion of sleep

161 we further show that age-related psychomotor slowing is partially mediated by inflammation.

162 These results suggest slow oscillation focal slowing is reduced near the seizure onset zone, perhaps

163 Arsenite also stabilized GADD34 protein, slowing its degradation.

164 actors involved in delaying myopia onset and slowing its progression will be key to reducing the rapi

165 arge crossing Kv4.3 channels in CHO cells by slowing Kv4.3 inactivation kinetics.

166 e decisions, the network exhibits post-error slowing (longer reaction times after error trials) and p

167 Focal slowing (<4 Hz) of brain waves is often associated with

168 ucing spontaneous action potential firing by slowing maximum depolarization rate.

169 Prior work suggests that slowing may be comprised of at least two distinct neural

170 This slowing may be of importance in enhancing chemical decon

171 Prematurely slowing MCM loading in pluripotent cells not only length

172 etic resonance imaging (NM-MRI)-and baseline slowing measured by the Digit Symbol test and a gait spe

173 ble that the findings represent a biological slowing mechanism in response to extensive fetal develop

174 of life, representing a possible biological slowing mechanism.

175 Furthermore, we show that drive depends on slowing meiotic progression, suggesting that selfish cen

176 Slowing myopia progression could decrease the risk of si

177 nce-based treatment shown to be effective in slowing myopia progression in children.

178 Overnight orthokeratology was effective in slowing myopia progression over a twelve-year follow-up

179 Orthokeratology may be effective in slowing myopic progression for children and adolescents,

180 e activation of microglia that is capable of slowing neural information processing.

181 nd/or alter relative state energies, thereby slowing nonradiative loss of charge-transfer energy.

182 imulation (>/=1 Hz) results in a progressive slowing of action potential conduction velocity, which m

183 aled that increasing age was associated with slowing of action selection performance.

184 progenitor cell-secreted exosomes led to the slowing of ageing.

185 These visual approaches suggest a selective slowing of anterograde transport relative to 3 different

186 to E1, and the cholesterol depletion-induced slowing of ATP phosphorylation kinetics was consistent w

187 metabolism at acidic pH that results in the slowing of bacterial growth and changes in redox homeost

188 these results demonstrate that inhibition or slowing of canonical pre-mRNA processing events shifts t

189 site annihilation and reordering, and thus a slowing of cation transport.

190 ir metabolism, attenuation of ERK signaling, slowing of cell proliferation, and biasing of the MEPs t

191 s inflammation and fibrosis that may lead to slowing of CKD progression.

192 ing the percentage of DMPC leads to a marked slowing of CNTP diffusion.

193 that this occurs through Dispatched-mediated slowing of cytoneme retraction rates.

194 polarizing shift in voltage sensitivity, and slowing of deactivation in response to a depolarizing pr

195 We propose that this slowing of deep-to-surface circulation (i.e., a longer r

196 -telangiectasia mutated) activity leads to a slowing of DNA repair and an accumulation of cytoplasmic

197 oxidation of Pol delta reveal a significant slowing of DNA synthesis that can be fully reversed by r

198 Slowing of dopamine transients is observed with age in l

199 ism without epilepsy, we observed a dramatic slowing of fast inactivation in neuroblastoma cells, whi

200 vity with gain-of-function, characterized by slowing of fast inactivation, acceleration of its recove

201 There was a protein load-dependent slowing of gastric emptying, an increase in concentratio

202 ies, with deviations to account for observed slowing of growth rate only at higher densities due to l

203 it exhibit a phenotype including unexplained slowing of heart rate (bradycardia).

204 f skeletal muscle contractility ex vivo, and slowing of in vitro actin-sliding velocity were measured

205 ced concurrent Kv3.4 current attenuation and slowing of inactivation.

206 round state cooling of mechanical motion and slowing of light.

207 erved less increase in current density, less slowing of macroscopic current decay, less acceleration

208 The results indicate a slowing of microstate dynamics and disturbances to the p

209 ent in ATM or NBN did not show a significant slowing of mitotic progression.

210 r features of the disease, including tremor, slowing of movement (bradykinesia), and rigidity.

211 While heterozygous fibres showed no overall slowing of muscle kinetics, active force and work produc

212 ral neuropathy with hypo- and demyelination, slowing of nerve conduction velocities and disturbed nod

213 pment revealed an unexpected and substantial slowing of parasite maturation in acutely infected mice,

214 ro at nonzero momentum, indicating dynamical slowing of plasma fluctuations and crystallization of th

215 Oppositely, slowing of pore kinetics by the SNARE-regulator complexi

216 CK-2066260 induced a slowing of relaxation, which was markedly larger at 26 d

217 results in accumulation of RNA-DNA hybrids, slowing of replication forks, and increased DNA damage.

218 XL413 stimulates HDR during a reversible slowing of S-phase that is unexplored for Cas9-induced H

219 There was a significant slowing of saccades and saccades became less accurate wi

220 ical study of GM1 in PD patients that showed slowing of symptom progression with chronic use, and arg

221 However, due to the slowing of the antibiotic pipeline and the rapid emergen

222 ater from Greenland will lead to substantial slowing of the Atlantic overturning circulation, and tha

223 the visual P100 latency, greater MSI-related slowing of the auditory P200 and an overall temporally d

224 The mutant displays a marked slowing of the Ca(2+)-binding kinetics, and its crystal

225 We propose that developmental slowing of the cell cycle times embryonic heterochromati

226 pansion, widespread EEG synchronization, and slowing of the ictal rhythm as the seizure approaches te

227 gradual reduction in mHR with age reflects a slowing of the intrinsic pacemaker activity of the sinoa

228 ajor changes in ocean circulation, including slowing of the North Atlantic Current and diversion of A

229 ity in the basal ganglia are associated with slowing of voluntary movement in patients with Parkinson

230 ation energy of decomposition, indicating a "slowing" of this fundamental ecosystem process in respon

231 motor neuron firing typically underlies the slowing often present at the end of human reaches.

232 f this decline has raised the possibility of slowing or delaying age-related kidney disease.

233 thought to interfere with DNA replication by slowing or impeding replication fork progression.

234 water depth, stabilizing grounding lines and slowing or reversing glacial retreat.

235 Slowing or reversing the progression of cardiac remodeli

236 fectiveness of conservation efforts aimed at slowing or reversing these losses.

237 1 PH rats, whereas no significant conduction slowing or rotor activity occurred in the LA of monocrot

238 Patients suffering from cholestasis, the slowing or stoppage of bile flow, commonly report experi

239 the long-standing evidence of a relative EEG slowing over the injured hemisphere.

240 ue to the attenuation of conduction velocity slowing (p = 0.03), and the preservation of Connexin43 p

241 was created that extends apple shelf-life by slowing Penicillium expansum growth.

242 ents on subsequent trials such as post-error slowing (PES).

243 ting both pathways will be more effective at slowing photoreceptor cell death caused by elevated cGMP

244 This represents a 27% improvement in the slowing produced by traumatic brain injury.

245 ta sources remains a considerable challenge, slowing progress toward a global synthesis to integrate

246 However, SNL treatment may have a role in slowing progression for those without coexistent RPD and

247 Systemic sunitinib malate may be useful in slowing progression of ocular disease from VHL-associate

248 f SNL treatment in iAMD and its efficacy for slowing progression to late AMD.

249 on historical patterns and allowing for the slowing rate of expansion, 1 million more motorized vess

250 1-2 years), then continued to decrease in a slowing rate.

251 tion rates simultaneously declines, possibly slowing regional PM(2.5) formation.

252 ) is safe and more effective than placebo in slowing renal function loss in patients with diabetic ne

253 raquine by increasing cure rates and thereby slowing resistance development.

254 orting antibiotic susceptibility profiles on slowing resistance spread.

255 ygen (O2 ) consumption in a paracrine way by slowing respiration at the mitochondrial electron transp

256 d the rate of IM transport to the OM by 50%, slowing shrinkage of the IM and delaying lysis.

257 on to reproductive isolation and potentially slowing speciation.

258 By slowing substrate delivery to lysosomes, autophagosome m

259 nsory evoked potentials demonstrated central slowing supporting myelopathy (96%).

260 S may provide an arrhythmogenic substrate by slowing the Ca(2+) transient decline, as well as by ampl

261 other hand, gamma-4 has a stronger effect on slowing the channel desensitization rate than gamma-2; y

262 le management of the agricultural matrix and slowing the conversion of forests to agriculture are imp

263 distancing measures have proven effective in slowing the coronavirus disease 2019 (COVID-19) pandemic

264 ugh direct hydrogen-bonding, positioning and slowing the dynamics of water at the trough of the bindi

265 herapeutic strategies aimed at preventing or slowing the emergence of dementia.SIGNIFICANCE STATEMENT

266 cing and mask-wearing, although effective in slowing the epidemic and in reducing mortality, would al

267 Slowing the evolution of antimicrobial resistance is ess

268 efficacy and safety of avacincaptad pegol in slowing the GA growth (GATHER2 Study).

269 ivity not by ER elimination, but by markedly slowing the intra-nuclear mobility of ER.

270 at controlling exaggerated inflammation and slowing the long-term decline of lung function in patien

271 -fidelity variants improve discrimination by slowing the observed rate of cleavage without increasing

272 t sustaining beta cell mass may be useful in slowing the onset of CFRD.

273 olymer-supported membrane, it acts as a net, slowing the passage of large ions while letting smaller

274 activation in planta Our findings show that slowing the phototropin photocycle enhanced several ligh

275 These measures are effective in slowing the progression of atherosclerotic disease and i

276 s evidence suggesting a protective effect in slowing the progression of GA.

277 rmacological therapies that are effective in slowing the progression of idiopathic pulmonary fibrosis

278 ng; and (5) establishes the effectiveness of slowing the progression of murine lung fibrosis with the

279 nly current recommendation for preventing or slowing the progression of peripheral neuropathy is to m

280 red to symptomatic patients rather than just slowing the progression of the disease.

281 formation in the presence of LMW-heparin and slowing the rate at higher concentrations.

282 rtant negative feedback to climate change by slowing the rate of increase of the atmospheric CO(2) co

283 corticoids enhance erythrocyte production by slowing the rate of progression through this development

284 ow failure, are believed to drive disease by slowing the rate of protein synthesis.

285 PP plays a multifaceted role, slowing the reaction by complexing both Mn(II) and Mn(II

286 The hairpin acts as a road block slowing the translocation rate.

287 H minimizes the hydrolysis of nucleotides by slowing their reaction with RppH, they nevertheless comp

288 Water slows H(2) activation by slowing this H(+) transfer, forcing negative charge buil

289 adual reduction in movement speed (or 'motor slowing') to study the central component of fatigability

290 outcomes that matter most to patients, thus slowing transformation to higher-value team-based care.

291 No disease-slowing treatment exists for Huntington's disease, but i

292 L), PD1 expression, and tumor necrosis while slowing tumor growth and modestly increasing mouse survi

293 e infiltration of leukocytes into the tumor, slowing tumor growth and preventing metastasis in poorly

294 on proteolysis and network interactions, and slowing turnover affects tissue morphogenesis.

295 In contrast to sleep, postictal slowing was characterized by a broadband increase of spe

296 rlap of bursts between the two STN was high, slowing was more pronounced.

297 rrent density, whereas structural conduction slowing was represented by decreasing tissue conductivit

298 en coated on human skin, they are capable of slowing water evaporation and keeping the tissue hydrate

299 manner: theta correlated with response time slowing when the number of rules increased, whereas delt

300 flex vagal activity causes abrupt heart rate slowing with concomitant caudal shifts of the leading pa