ライフサイエンスコーパス: small nuclear ribonucleoprotein

1 lation site, independent of the U1 snRNP (U1 small nuclear ribonucleoprotein).

2 rs such as Lsm11, a core component of the U7 small nuclear ribonucleoprotein.

3 PRP8 (R1753K), a protein component of the U5 small nuclear ribonucleoprotein.

4 of the 70-kDa subunit of U1 snRNP (U1-70kDa) small nuclear ribonucleoprotein.

5 of the 5' splice site of pre-mRNAs by the U1 small nuclear ribonucleoprotein.

6 ily, interact with the 70k protein of the U1 small nuclear ribonucleoprotein.

7 licing is mediated by the proteins of the U2 small nuclear ribonucleoprotein.

8 ding proteins (RBPs): lupus La and 70-kDa U1 small nuclear ribonucleoprotein.

9 that are suppressed, at least in part, by U1 small nuclear ribonucleoproteins.

10 which contain mostly nonoverlapping sets of small nuclear ribonucleoproteins.

11 pliceosome type resides in the U6 and U6atac small nuclear ribonucleoproteins.

12 omponent complex involved in the assembly of small nuclear ribonucleoproteins.

13 ated with the Sm core domain of spliceosomal small nuclear ribonucleoproteins.

14 ex required for the assembly of spliceosomal small nuclear ribonucleoproteins.

15 e complexes with stably bound U2, U5, and U6 small nuclear ribonucleoproteins.

16 The U1 small nuclear ribonucleoprotein 70-kDa protein, a U1 sma

17 he present study, we characterized U1-70-kDa small nuclear ribonucleoprotein (70-kDa) autoantigen-spe

18 t is characterized by high levels of anti-U1 small nuclear ribonucleoprotein 70k autoantibodies and a

19 Basophil activation and IgE anti-U1 small nuclear ribonucleoprotein 70k were also observed i

20 raised against the main MCTD autoantigen U1 small nuclear ribonucleoprotein 70k were found in nearly

21 It exists in inactive small nuclear ribonucleoprotein (7SK snRNP) and active (

22 EFb) via its release from the inhibitory 7SK small nuclear ribonucleoprotein (7SK snRNP).

23 ) kinase, which is suppressed within the 7SK small nuclear ribonucleoprotein (7SK snRNP).

24 To determine whether U1 small nuclear ribonucleoprotein, a multicomponent splici

25 r messenger RNAs (pre-mRNAs) contains the U7 small nuclear ribonucleoprotein and shares the key cleav

26 ex functions in the assembly of spliceosomal small nuclear ribonucleoproteins and probably other ribo

27 ceosome from analysis of individual purified small nuclear ribonucleoproteins and salt-stable spliceo

28 ort of spliced mRNA, small nuclear RNAs, and small nuclear ribonucleoproteins and slow the nuclear tr

29 uclear domain important to the biogenesis of small nuclear ribonucleoproteins and telomerase, complex

30 nts, FLICE-associated huge protein, Mute, U7 small nuclear ribonucleoprotein, and MPM-2 phosphoepitop

31 ) were found in two other human proteins, U5 small nuclear ribonucleoprotein, and transcription facto

32 erved previously in myelin basic protein, Sm small nuclear ribonucleoproteins, and other polypeptides

33 In contrast, trimethylguanosine-capped small nuclear ribonucleoproteins are predominantly local

34 evidence indicates that U1-70K and other U1 small nuclear ribonucleoproteins are Sarkosyl-insoluble

35 NAs can associate with Sm protein-containing small nuclear ribonucleoproteins, as judged by immunopre

36 ressed in metazoan cells and plays a role in small nuclear ribonucleoprotein assembly and pre-mRNA sp

37 to understand the mechanism of SMN-assisted small nuclear ribonucleoprotein assembly and the underly

38 Here we show that GEMIN2, a spliceosomal small nuclear ribonucleoprotein assembly factor conserve

39 pICln, SMN and Gemin5, which are involved in small nuclear ribonucleoprotein assembly, have an import

40 well characterized function in spliceosomal small nuclear ribonucleoprotein assembly.

41 -COP protein co-immunoprecipitates with SMN, small nuclear ribonucleoprotein-associated assembly fact

42 SFPS colocalizes with U2 small nuclear ribonucleoprotein-associated factors inclu

43 nal transcribed allele of the imprinted gene Small nuclear ribonucleoprotein-associated polypeptide N

44 r for plasmid DNA, exon-1 from the imprinted small nuclear ribonucleoprotein-associated polypeptide N

45 at sequential addition of the U4/U6 proteins small nuclear ribonucleoprotein-associated protein 1 (Sn

46 ive, varied immune response against multiple small nuclear ribonucleoprotein autoantigens similar to

47 hanced complex A formation and binding of U2 small nuclear ribonucleoprotein auxiliary factor 65 kDa

48 d splicing regulatory proteins, including u2 small nuclear ribonucleoprotein auxiliary factor 65-kDa

49 We reveal that the splicing factor U2 small nuclear ribonucleoprotein auxiliary factor 65-kilo

50 U2AF (U2 small nuclear ribonucleoprotein auxiliary factor) is an

51 onucleoprotein polypeptide N), and U2af1 (U2 small nuclear ribonucleoprotein auxiliary factor), remai

52 es assembled on pre-mRNA, blocking U1 snRNP (small nuclear ribonucleoprotein) binding and exon inclus

53 PID in the liberation of P-TEFb from the 7SK small nuclear ribonucleoprotein complex (7SK snPNP).

54 ibitor (PSI) and its interaction with the U1 small nuclear ribonucleoprotein complex (snRNP) control

55 luded diverse components of the U4/U6.U5 tri-small nuclear ribonucleoprotein complex and several spli

56 -B, that are physically associated in the U1-small nuclear ribonucleoprotein complex and that are fre

57 rays revealed that serum anti-Smith and anti-small nuclear ribonucleoprotein complex autoantibodies,

58 clin T1 and CDK9 are incorporated in the 7SK small nuclear ribonucleoprotein complex containing the i

59 Its release from the inactive 7SK small nuclear ribonucleoprotein complex is a critical st

60 ncode core components of the spliceosomal U6 small nuclear ribonucleoprotein complex, regulate circad

61 r complexes, or associated with the U4/U6.U5 small nuclear ribonucleoprotein complex.

62 end prior to incorporation into the U4 x U6 small nuclear ribonucleoprotein complex.

63 plicing complex Bact consisting of the three small nuclear ribonucleoprotein complexes (snRNPs) U2, U

64 ltimeric complex involved in the assembly of small nuclear ribonucleoprotein complexes (snRNPs).

65 ckdown of proteins associated with different small nuclear ribonucleoprotein complexes and by using t

66 es are capable of immunoprecipitating native small nuclear ribonucleoprotein complexes.

67 osophila homologue of Prp38p (dPrp38), a tri-small nuclear ribonucleoprotein component, and is requir

68 findings imply that these two genes encoding small nuclear ribonucleoprotein components are subject t

69 tein complex with the methylosome components small nuclear ribonucleoprotein D3b (SmD3b) and protein

70 Brr2 enzyme, which is essential for U4/U6 di-small nuclear ribonucleoprotein disruption during splice

71 ntial role in the biogenesis of spliceosomal small nuclear ribonucleoproteins in all tissues.

72 cts with several Sm proteins of spliceosomal small nuclear ribonucleoproteins, in particular, with Sm

73 The U1 and U11 small nuclear ribonucleoproteins interact with sequences

74 erlying the conversion of soluble nuclear U1 small nuclear ribonucleoproteins into insoluble cytoplas

75 mammalian 70K protein, a component of the U1 small nuclear ribonucleoprotein involved in pre-mRNA spl

76 The U6 small nuclear ribonucleoprotein is a critical component

77 proteins found in the U1 and U2 spliceosomal small nuclear ribonucleoproteins is highly conserved.

78 ts some novel functions for Snp1p and the U1 small nuclear ribonucleoprotein late in spliceosome deve

79 of PWS carrying a paternal (p) deletion from small nuclear ribonucleoprotein N (Snrpn (S)) to ubiquit

80 n, t(15;19)(q12;q13.41), which disrupted the small nuclear ribonucleoprotein N (SNRPN) locus.

81 and humans, the locus encoding the gene for small nuclear ribonucleoprotein N (SNRPN/Snrpn), as well

82 tends approximately 450 kb to UBE3A from the small nuclear ribonucleoprotein N (SNURF/SNRPN) promoter

83 otein that is found in the U1 and U2 snRNPs (small nuclear ribonucleoproteins) of Drosophila.

84 x, SF3B3 and SF3B5, that form part of the U2 small nuclear ribonucleoprotein particle (snRNP) are als

85 The mobile U2 small nuclear ribonucleoprotein particle (snRNP) associa

86 snRNP and the polypyrimidine tract by the U2 small nuclear ribonucleoprotein particle (snRNP) auxilia

87 The U2 small nuclear ribonucleoprotein particle (snRNP) auxilia

88 Prp24 is a component of the free U6 small nuclear ribonucleoprotein particle (snRNP) but not

89 he 5' splice site, and a component of the U2 small nuclear ribonucleoprotein particle (snRNP) complex

90 k9-cyclin T modules from large, inactive 7SK small nuclear ribonucleoprotein particle (snRNP) complex

91 In this investigation, we made use of anti-small nuclear ribonucleoprotein particle (snRNP) Ig tran

92 The current model for the function of the U5 small nuclear ribonucleoprotein particle (snRNP) in the

93 t dephosphorylated SRp38 interacts with a U1 small nuclear ribonucleoprotein particle (snRNP) protein

94 s shown to promote the recruitment of the U1 small nuclear ribonucleoprotein particle (snRNP) to the

95 This requires the interaction of the U7 small nuclear ribonucleoprotein particle (snRNP) with a

96 Previous work demonstrated that U1 small nuclear ribonucleoprotein particle (snRNP), bound

97 Coiled bodies also contain the U7 small nuclear ribonucleoprotein particle (snRNP), which

98 r RNA (pre-mRNA) splicing, as part of the U1 small nuclear ribonucleoprotein particle (snRNP).

99 early intron recognition factors U2AF and U1 small nuclear ribonucleoprotein particle (snRNP).

100 The U1 small nuclear ribonucleoprotein particle (U1 snRNP) 70K

101 The product of the U1 small nuclear ribonucleoprotein particle (U1 snRNP) 70K

102 ) domain of spliceosomal A protein of the U1 small nuclear ribonucleoprotein particle (U1A) interacti

103 The pre-mRNA splicing factor U2AF (U2 small nuclear ribonucleoprotein particle [snRNP] auxilia

104 was detected in association with a subset of small nuclear ribonucleoprotein particle and Ser-Arg pro

105 esidues 885-2413) in complex with Aar2, a U5 small nuclear ribonucleoprotein particle assembly factor

106 This focused attention on the U2 small nuclear ribonucleoprotein particle auxiliary splic

107 Targeting a lupus autoantigen, the small nuclear ribonucleoprotein particle D protein, to t

108 and trans-splicing using the specialized SL2 small nuclear ribonucleoprotein particle for downstream

109 thereby promoting the dissociation of the U1 small nuclear ribonucleoprotein particle from the 5' spl

110 hat SmD1, a core component of the Drosophila small nuclear ribonucleoprotein particle implicated in s

111 40, indicating that Prp40 is bound to the U1 small nuclear ribonucleoprotein particle in vivo.

112 the 5' splice site, cross-linking of the U5 small nuclear ribonucleoprotein particle protein, U5(200

113 been shown to encode a Drosophila U1 and U2 small nuclear ribonucleoprotein particle protein.

114 l nuclear ribonucleoprotein (snRNP) is a 25S small nuclear ribonucleoprotein particle similar in size

115 The U1 small nuclear ribonucleoprotein particle U1C protein has

116 which facilitates the interaction of the U2 small nuclear ribonucleoprotein particle with the branch

117 ceosome assembly within the mature U2 snRNP (small nuclear ribonucleoprotein particle), and its displ

118 Prp8, a component of the U5 small nuclear ribonucleoprotein particle, crosslinks ext

119 The A protein of the U1 small nuclear ribonucleoprotein particle, interacting wi

120 IIF (TFIIF), TFIIS, splicing factors, the U7 small nuclear ribonucleoprotein particle, the stem-loop

121 nd in a manner independent of Prp16p, the U5 small nuclear ribonucleoprotein particle-associated prot

122 icing in C. merolae may occur without the U1 small nuclear ribonucleoprotein particle.

123 -B7.2 Abs expressed significantly lower anti-small nuclear ribonucleoprotein particles (snRNP) and an

124 of these introns requires a different set of small nuclear ribonucleoprotein particles (snRNPs) (U11,

125 When Prp24 is absent, unpaired U4 and U6 small nuclear ribonucleoprotein particles (snRNPs) accum

126 functions in the biogenesis of spliceosomal small nuclear ribonucleoprotein particles (snRNPs) and p

127 The U1, U2, U4, U5 and U6 small nuclear ribonucleoprotein particles (snRNPs) are e

128 The U1, U2, U4/U6, and U5 small nuclear ribonucleoprotein particles (snRNPs) invol

129 site for the Sm proteins, both hallmarks of small nuclear ribonucleoprotein particles (snRNPs) that

130 cipitation (ChIP) analysis of U1, U2, and U5 small nuclear ribonucleoprotein particles (snRNPs) to in

131 r messenger RNA substrate bound to U1 and U2 small nuclear ribonucleoprotein particles (snRNPs), and

132 Sm proteins form the core of small nuclear ribonucleoprotein particles (snRNPs), maki

133 tion as an assembly machine for spliceosomal small nuclear ribonucleoprotein particles (snRNPs), the

134 Human spliceosomal U1 small nuclear ribonucleoprotein particles (snRNPs), whic

135 a complex that functions in the assembly of small nuclear ribonucleoprotein particles (snRNPs).

136 by the spliceosome, a complex of five major small nuclear ribonucleoprotein particles (snRNPs).

137 B" and is an integral component of U1 and U2 small nuclear ribonucleoprotein particles (snRNPs).

138 mplex containing U1, U2, U5 and duplex U4/U6 small nuclear ribonucleoprotein particles (snRNPs).

139 nucleotides, a method that was developed for small nuclear ribonucleoprotein particles (snRNPs).

140 of Sm core structures of spliceosomal U-rich small nuclear ribonucleoprotein particles (UsnRNPs) requ

141 strictive temperature (39.5 degrees C), both small nuclear ribonucleoprotein particles and a general

142 he U12-type spliceosomes, large complexes of small nuclear ribonucleoprotein particles and associated

143 LIP, which immunoprecipitates SmB along with small nuclear ribonucleoprotein particles and auxiliary

144 ke proteins are stable components of several small nuclear ribonucleoprotein particles that function

145 autoreactive B cells that recognize self-Ag small nuclear ribonucleoprotein particles with activated

146 important for the biogenesis of spliceosomal small nuclear ribonucleoprotein particles, but downstrea

147 tion occurred after inactivation of U1 or U2 small nuclear ribonucleoprotein particles, compatible wi

148 d the spliceosome, which is composed of five small nuclear ribonucleoprotein particles, U1, U2, U4/U6

149 Prp18 forms a bridge between Slu7 and the U5 small nuclear ribonucleoprotein particles.

150 o alpha-helices and may interact with the U5 small nuclear ribonucleoprotein particles.

151 l microdeletions within the 5' region of the small nuclear ribonucleoprotein polypeptide N ( SNRPN )

152 bserved at maternally methylated ICs such as small nuclear ribonucleoprotein polypeptide N (SNRPN), S

153 The human SNRPN (small nuclear ribonucleoprotein polypeptide N) gene is o

154 nscript), Sgce (epsilon-sarcoglycan), Snrpn (small nuclear ribonucleoprotein polypeptide N), and U2af

155 3), insulin-like growth factor 2 (IGF2), and small nuclear ribonucleoprotein polypeptide N, and the l

156 mplicated in the biogenesis of several other small nuclear ribonucleoproteins required for processing

157 nting stable recruitment of the U4/U5/U6 tri-small nuclear ribonucleoprotein, resulting in accumulati

158 rs include histone, a protein component of a small nuclear ribonucleoprotein, ribosomal proteins, and

159 aled that these structures contained the non-small nuclear ribonucleoprotein RNA processing factor, S

160 We show that newly assembled small nuclear ribonucleoprotein (RNP [snRNP]) particles,

161 he CB, such as the SMN complex, spliceosomal small nuclear ribonucleoproteins (RNPs), small nucleolar

162 l domain has a protein fold similar to human small nuclear ribonucleoprotein Sm D3 and Haloarcula mar

163 ted with B7 blocking Abs exhibit strong anti-small nuclear ribonucleoprotein (snRNP) and anti-DNA aut

164 scovered an RNA motif that recognizes the U1 small nuclear ribonucleoprotein (snRNP) and is essential

165 splicing pathway through association with U1 small nuclear ribonucleoprotein (snRNP) and non-snRNP sp

166 duction, as seen in serum Ig, anti-DNA, anti-small nuclear ribonucleoprotein (snRNP) and rheumatoid f

167 pathway and involves interactions between U1 small nuclear ribonucleoprotein (snRNP) and the pre-mRNA

168 The SMN protein is important in small nuclear ribonucleoprotein (snRNP) assembly and int

169 issense mutants can rescue iMEF survival and small nuclear ribonucleoprotein (snRNP) assembly, demons

170 SMN is critical for small nuclear ribonucleoprotein (snRNP) assembly.

171 which were associated with an improvement in small nuclear ribonucleoprotein (snRNP) assembly.

172 compared with SMN likely leading to loss of small nuclear ribonucleoprotein (snRNP) assembly.

173 esting an unknown quality control system for small nuclear ribonucleoprotein (snRNP) assembly.

174 We previously showed that U1 small nuclear ribonucleoprotein (snRNP) associates with

175 RE consists of a single 9-nucleotide (nt) U1 small nuclear ribonucleoprotein (snRNP) base pairing sit

176 Definition occurs by U1 small nuclear ribonucleoprotein (snRNP) binding the 5' S

177 class 5' splice site and is required for U11 small nuclear ribonucleoprotein (snRNP) binding to the N

178 and Gemin4, and it plays important roles in small nuclear ribonucleoprotein (snRNP) biogenesis and i

179 N has been shown to function in spliceosomal small nuclear ribonucleoprotein (snRNP) biogenesis and p

180 tein plays an important role in spliceosomal small nuclear ribonucleoprotein (snRNP) biogenesis and t

181 U6 small nuclear ribonucleoprotein (snRNP) biogenesis is es

182 urney to the spliceosome.The mechanism of U6 small nuclear ribonucleoprotein (snRNP) biogenesis is no

183 SMN functions in small nuclear ribonucleoprotein (snRNP) biogenesis, but

184 trates within Cajal bodies (CBs) and impacts small nuclear ribonucleoprotein (snRNP) biogenesis.

185 s (CBs) are subnuclear domains implicated in small nuclear ribonucleoprotein (snRNP) biogenesis.

186 Nuclear import is an essential step in small nuclear ribonucleoprotein (snRNP) biogenesis.

187 stered into a transcriptionally inactive 7SK small nuclear ribonucleoprotein (snRNP) by the coordinat

188 Interestingly, canonical CB foci and coilin/small nuclear ribonucleoprotein (snRNP) co-localization

189 Sera known to recognize the U1-small nuclear ribonucleoprotein (snRNP) complex (confirm

190 eoli and bound what we believe to be a novel small nuclear ribonucleoprotein (snRNP) complex composed

191 Autoantibody response against the small nuclear ribonucleoprotein (snRNP) complex is a cha

192 essential gene encoding a subunit of the U5 small nuclear ribonucleoprotein (snRNP) complex of the s

193 binds 7SK RNA and, as a component of the 7SK small nuclear ribonucleoprotein (snRNP) complex, is recr

194 se mice do not develop autoantibodies to the small nuclear ribonucleoprotein (snRNP) complex.

195 atalytically inactive state bound to the 7SK small nuclear ribonucleoprotein (snRNP) complex.

196 ol II) once released from the inhibitory 7SK small nuclear ribonucleoprotein (snRNP) complex.

197 ) complex is essential for the biogenesis of small nuclear ribonucleoprotein (snRNP) complexes in euk

198 many splicing factors, including the key U2 small nuclear ribonucleoprotein (snRNP) component SF3B1

199 spliceostatin A, sudemycin E binds to the U2 small nuclear ribonucleoprotein (snRNP) component SF3B1.

200 7, 251, 261 and 271 residues of MoSNP1, a U1 small nuclear ribonucleoprotein (snRNP) component, likel

201 The small nuclear ribonucleoprotein (snRNP) core domain, act

202 otor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein (snRNP) core particles.

203 Pre-mRNA binding to the yeast U2 small nuclear ribonucleoprotein (snRNP) during presplice

204 In eukaryotes, U1 small nuclear ribonucleoprotein (snRNP) forms spliceosom

205 The U2 small nuclear ribonucleoprotein (snRNP) has an essential

206 The yeast U4/U6.U5 pre-mRNA splicing small nuclear ribonucleoprotein (snRNP) is a 25S small n

207 The initial steps of spliceosomal small nuclear ribonucleoprotein (snRNP) maturation take

208 U1 small nuclear ribonucleoprotein (snRNP) may function dur

209 licing factor Tat-SF1 associates with the U2 small nuclear ribonucleoprotein (snRNP) of the spliceoso

210 8p is a unique component of the U4/U6.U5 tri-small nuclear ribonucleoprotein (snRNP) particle and is

211 association of PSI with the spliceosomal U1 small nuclear ribonucleoprotein (snRNP) particle in soma

212 thway of subunit addition that includes both small nuclear ribonucleoprotein (snRNP) particles and no

213 In addition to La and Ro52, proteins in the small nuclear ribonucleoprotein (snRNP) particles such a

214 ous nuclear ribonucleoproteins (hnRNPs), and small nuclear ribonucleoprotein (snRNP) particles throug

215 The 7SK small nuclear ribonucleoprotein (snRNP) plays a central

216 novo motif analysis shows PAS signals and U1 small nuclear ribonucleoprotein (snRNP) recognition site

217 The 7SK small nuclear ribonucleoprotein (snRNP) sequesters and i

218 ing protein 1, and with several spliceosomal small nuclear ribonucleoprotein (snRNP) Sm proteins.

219 olecular recognition of tau pre-mRNA by a U1 small nuclear ribonucleoprotein (snRNP) splicing factor.

220 Stable addition of U2 small nuclear ribonucleoprotein (snRNP) to form the pres

221 ds to exon 3 of the pre-mRNA and recruits U1 small nuclear ribonucleoprotein (snRNP) to the F1 pseudo

222 The Ul small nuclear ribonucleoprotein (snRNP), a complex of ni

223 nisms that regulate P-TEFb involving the 7SK small nuclear ribonucleoprotein (snRNP), factors that co

224 splicing factor compartment (SFC) [e.g. the small nuclear ribonucleoprotein (snRNP), U2B, and serine

225 p80-coilin, which is colocalized with the U7 small nuclear ribonucleoprotein (snRNP), whereas the att

226 is inhibited by HEXIM1 or HEXIM2 in the 7SK small nuclear ribonucleoprotein (snRNP), which contains,

227 U1 small nuclear ribonucleoprotein (snRNP)-70K (U1-70K), a

228 ctions of individual SR proteins with the U1 small nuclear ribonucleoprotein (snRNP)-associated 70-kD

229 In Caenorhabditis elegans, the small nuclear ribonucleoprotein (snRNP)-associated prote

230 Both the BBR and BPS interact with the U2 small nuclear ribonucleoprotein (snRNP)-associated SF3b

231 U1C is one of the three human U1 small nuclear ribonucleoprotein (snRNP)-specific protein

232 loop by an endonuclease dependent on the U7 small nuclear ribonucleoprotein (snRNP).

233 functions only if it is assembled into an Sm small nuclear ribonucleoprotein (snRNP).

234 eins or release P-TEFb from the inactive 7SK small nuclear ribonucleoprotein (snRNP).

235 ylating the RNA, likely by competing with U1 small nuclear ribonucleoprotein (snRNP).

236 spliceosome is a complex machine composed of small nuclear ribonucleoproteins (snRNPs) and accessory

237 olyadenylation and was recognized by both U1 small nuclear ribonucleoproteins (snRNPs) and alternativ

238 clear organelles that are highly enriched in small nuclear ribonucleoproteins (snRNPs) and certain ba

239 ntial role in the production of spliceosomal small nuclear ribonucleoproteins (snRNPs) and likely oth

240 mportant role in the cytoplasmic assembly of small nuclear ribonucleoproteins (snRNPs) and likely oth

241 dynamic RNA-protein machinery consisting of small nuclear ribonucleoproteins (snRNPs) and non-snRNP

242 a key role in the biogenesis of spliceosomal small nuclear ribonucleoproteins (snRNPs) and other ribo

243 nslational modification in the biogenesis of small nuclear ribonucleoproteins (snRNPs) and pre-mRNA s

244 s a role in the assembly and regeneration of small nuclear ribonucleoproteins (snRNPs) and spliceosom

245 Small nuclear ribonucleoproteins (snRNPs) are core compo

246 rine-arginine (SR) proteins, U1snRNP, and U6 small nuclear ribonucleoproteins (snRNPs) are implicated

247 tterns of autoantibody reactivities with the small nuclear ribonucleoproteins (snRNPs) are observed i

248 essential for the biogenesis of spliceosomal small nuclear ribonucleoproteins (snRNPs) as it binds to

249 splicing factors SF2/ASF and U1, U2, and U11 small nuclear ribonucleoproteins (snRNPs) bind the NRS,

250 The prespliceosome, comprising U1 and U2 small nuclear ribonucleoproteins (snRNPs) bound to the p

251 The U1, U2, U4, U5, and U6 small nuclear ribonucleoproteins (snRNPs) form essential

252 d are associated with defects in assembly of small nuclear ribonucleoproteins (snRNPs) in vitro.

253 The spliceosomal U small nuclear ribonucleoproteins (snRNPs) interact with

254 5), which are required for the biogenesis of small nuclear ribonucleoproteins (snRNPs) involved in mR

255 Cytoplasmic assembly of Sm-class small nuclear ribonucleoproteins (snRNPs) is a central p

256 The assembly of metazoan Sm-class small nuclear ribonucleoproteins (snRNPs) is an elaborat

257 The U1 and U2 small nuclear ribonucleoproteins (snRNPs) mark an intron

258 machinery including SR proteins, U1 and U2, small nuclear ribonucleoproteins (snRNPs) of the major s

259 sequential recruitment and rearrangement of small nuclear ribonucleoproteins (snRNPs) on a pre-mRNA

260 rected cross-linking with in vitro assembled small nuclear ribonucleoproteins (snRNPs) or spliceosome

261 lear domains important for the biogenesis of small nuclear ribonucleoproteins (snRNPs) which function

262 ct with the Sm core proteins of spliceosomal small nuclear ribonucleoproteins (snRNPs), and they play

263 onents of the spliceosome, U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), contain seven

264 Because MAH does not bind small nuclear ribonucleoproteins (snRNPs), it appears to

265 N complex is essential for the biogenesis of small nuclear ribonucleoproteins (snRNPs), the major con

266 Small nuclear ribonucleoproteins (snRNPs), which are ess

267 E, F, and G, shared by U1, U2, U4-6, and U5 small nuclear ribonucleoproteins (snRNPs), while anti-nu

268 splicing, forming the cores of spliceosomal small nuclear ribonucleoproteins (snRNPs).

269 at functions in the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs).

270 x required for biogenesis of the Sm class of small nuclear ribonucleoproteins (snRNPs).

271 x that is required for biogenesis of various small nuclear ribonucleoproteins (snRNPs).

272 olism that accumulate high concentrations of small nuclear ribonucleoproteins (snRNPs).

273 suborganelles involved in the biogenesis of small nuclear ribonucleoproteins (snRNPs).

274 on of SMN is as an assembler of spliceosomal small nuclear ribonucleoproteins (snRNPs).

275 The human small nuclear ribonucleoprotein SNRPB ' /B gene is alter

276 clear ribonucleoprotein 70-kDa protein, a U1 small nuclear ribonucleoprotein-specific protein, has be

277 re we report that U1C, one of three human U1 small nuclear ribonucleoprotein-specific proteins, inter

278 d with an antibody to SC35, an essential non-small nuclear ribonucleoprotein splicing factor.

279 ormation of aberrant U11- and U12-containing small nuclear ribonucleoproteins that impair the efficie

280 mic acid, which releases P-TEFb from the 7SK small nuclear ribonucleoprotein, they turned green.

281 intron polypyrimidine tract and recruits U2 small nuclear ribonucleoprotein to the branch site.

282 as a base-paired complex within the U4/U6.U5 small nuclear ribonucleoprotein (tri-snRNP).

283 in the assembly of spliceosomal uridine-rich small nuclear ribonucleoprotein (U snRNP) complexes coul

284 Uridine-rich small nuclear ribonucleoproteins (U snRNPs) are involved

285 for novel peptide sequences in either p53 or small nuclear ribonucleoprotein-U (snRNP-U) and substant

286 R proteins but does not interact with the U1 small nuclear ribonucleoprotein U1-70K or the 35-kDa sub

287 he early spliceosome assembly begins with U1 small nuclear ribonucleoprotein (U1 snRNP) binding to th

288 n the disease, including U1-70K and other U1 small nuclear ribonucleoprotein (U1 snRNP) spliceosome c

289 the U1 small nuclear RNA component of the U1 small nuclear ribonucleoprotein (U1 snRNP) splicing fact

290 components of the spliceosomal subcomplex U1 small nuclear ribonucleoprotein (U1 snRNP).

291 ng factors (SR splicing factors) with the U1-small nuclear ribonucleoprotein (U1-snRNP) and U3-small

292 The U1-small nuclear ribonucleoprotein (U1-snRNP) that includes

293 Binding of U1 small nuclear ribonucleoprotein (U1snRNP) to DM20 is gre

294 me proteins associated with the uridine-rich small nuclear ribonucleoproteins U2, U5, and U6 and the

295 SF3B1), a key spliceosomal protein of the U2 small nuclear ribonucleoprotein (U2 snRNP).

296 The auxiliary factor of U2 small nuclear ribonucleoprotein (U2AF) facilitates branc

297 g in mammalian cell extracts requires the U7 small nuclear ribonucleoprotein (U7 snRNP) and an uniden

298 The U1A/U2B''/SNF family of small nuclear ribonucleoproteins uses a phylogenetically

299 bly of RNA-protein complexes of uridine-rich small nuclear ribonucleoproteins (UsnRNPs).

300 the latter, it is incorporated into the 7SK small nuclear ribonucleoprotein, which contains hexameth