ライフサイエンスコーパス: small ubiquitin-like modifier

1 g in aggregate clearance in the absence of a small ubiquitin-like modifier.

2 The novel targets were identified as the small ubiquitin-like modifier 1 (SUMO-1) activating enzy

3 The BRD, PHD, and ZZ domains interact with small ubiquitin-like modifier 1 (SUMO-1) and Ubc9, and f

4 HIV-1 p6 was found to interact with small ubiquitin-like modifier 1 (SUMO-1) as well as the

5 Small ubiquitin-like modifier 1 (SUMO-1) modification of

6 how that nonvisual arrestins are modified by small ubiquitin-like modifier 1 (SUMO-1) upon activation

7 quitin, it conjugates a ubiquitin homologue, small ubiquitin-like modifier 1 (SUMO-1), also known as

8 nal modification by the ubiquitin homologue, small ubiquitin-like modifier 1 (SUMO-1), has been estab

9 ed that Ubc9, an E2-like enzyme specific for small ubiquitin-like modifier 1 (Sumo-1), is required fo

10 We report small ubiquitin-like modifier 1 (SUMO1) as a major new p

11 its linker domain (K1646) preferentially by small ubiquitin-like modifier 1 (SUMO1).

12 ed that PKD2 channels are modified by SUMO1 (small ubiquitin-like modifier 1) protein in myocytes of

13 -Maf can be modified at lysine 33 by SUMO-1 (small ubiquitin-like modifier 1).

14 ns are posttranslationally modified by SUMO (small ubiquitin-like modifier)-1 and SUMO-3.

15 Here we describe the involvement of the small ubiquitin-like modifier-1 (SUMO-1) conjugation pat

16 or attachment of the ubiquitin-like protein, small ubiquitin-like modifier-1 (SUMO-1), and the conser

17 we demonstrated that GATA4 is sumoylated by small ubiquitin-like modifier-1 (SUMO-1), which resulted

18 inadvertently found that SnoN is modified by small ubiquitin-like modifier-1 (SUMO-1).

19 Here we show that CDK6 is modified by small ubiquitin-like modifier-1 (SUMO1) in glioblastoma,

20 We demonstrate that CBS is modified by the small ubiquitin-like modifier-1 protein (SUMO-I) under b

21 ents with COS-7 cells using PIAS and SUMO-1 (small ubiquitin-like modifier-1) expression vectors.

22 t of the ability of Ubc9 to transfer SUMO-1 (small ubiquitin-like modifier-1) to proteins.

23 CircRNF13 and Small Ubiquitin-like Modifier 2 (SUMO2) interactions wer

24 om RPA70, allowing RPA70 to be modified by a small ubiquitin-like modifier 2/3 (SUMO-2/3).

25 Here, we show that PIASy-mediated small ubiquitin-like modifier 2/3 (SUMO2/3) modification

26 dified in vivo on a single site (K53) by the small ubiquitin-like modifier-2 (SUMO-2).

27 s of full-length histone H2B modified by the small ubiquitin-like modifier-3 (SUMO-3) protein further

28 We cloned a new gene (SUMO4), encoding small ubiquitin-like modifier 4 protein, in the interval

29 Reversible modification of proteins by SUMO (small ubiquitin-like modifier) affects a large number of

30 Interactions of CaWss1 with Cdc48 and small ubiquitin-like modifier, although not strictly req

31 We found that SUMO (Small Ubiquitin-like Modifier) and SUMO ligase Ubc9 are

32 fect of AR SUMOylation (where SUMO indicates small ubiquitin-like modifier) by mutating conserved lys

33 Proteins that regulate poly-SUMO (small ubiquitin-like modifier) chain conjugates play imp

34 In some cases, the transcription factor is a small ubiquitin-like modifier conjugated directly, thus

35 abrata We identified the enzymes involved in small ubiquitin-like modifier conjugation and show that

36 Small ubiquitin-like modifier conjugation represents a n

37 SUMO (Small Ubiquitin-like Modifier) conjugation onto target p

38 posttranslational modification by the SUMO (small ubiquitin-like modifier) conjugation pathway is es

39 Histones are substrates of the SUMO (small ubiquitin-like modifier) conjugation pathway.

40 SUMOylation (the process of SUMO [small ubiquitin-like modifier] conjugation to substrates

41 slation is accompanied by an increase in the small ubiquitin-like modifier-dependent nuclear localiza

42 nt in the cytoplasm and at S phase undergoes small ubiquitin-like modifier-dependent translocation to

43 In addition to small ubiquitin-like modifiers (e.g. Sumo and Nedd8), ub

44 e of Ubc8 among known ubiquitin E2s, nor the small ubiquitin-like modifier E2 Ubc9 supports protein I

45 n experiments suggest that PIAS3 acts as the small ubiquitin-like modifier E3 ligase for FOXP2 sumoyl

46 s levels of the deSUMOylating (where SUMO is small ubiquitin-like modifier) enzyme SENP1, leading to

47 critical E2-binding surface on the E1 of the small ubiquitin-like modifier has unusually high populat

48 SUMOylation (small ubiquitin-like modifier) in the DNA double-strand

49 is associated with its conjugation by SUMOs (small ubiquitin-like modifiers) in response to the topo

50 SUMO (small ubiquitin-like modifier) is a member of the ubiqui

51 Protein modification by SUMO (small ubiquitin-like modifier) is an important regulator

52 NA phosphodiesterase 2 and TOP2, an atypical small ubiquitin-like modifier ligase that directly inhib

53 se (MAPL) is an outer mitochondrial membrane small ubiquitin-like modifier ligase that is a key deter

54 nase C zeta and it's binding to the E3 SUMO (small ubiquitin-like modifier) ligase PIASy (protein inh

55 bers are ubiquitin-protein isopeptide ligase-small ubiquitin-like modifier ligases for diverse transc

56 inhibitor of activated STAT) family of SUMO (small ubiquitin-like modifier) ligases has been implicat

57 tors of Activated STAT 1) and PIAS3 E3 SUMO (small ubiquitin-like modifier)-ligases, at two conserved

58 alate development is beginning to emerge for small ubiquitin-like modifier modification, a widely use

59 argest groups of proteins regulated by SUMO (small ubiquitin-like modifier) modification, and their s

60 We found that the SUMO (small ubiquitin-like modifier)-modification and ubiquiti

61 ugh post-translational modification with the small ubiquitin-like modifier nedd8.

62 riguingly, SUMOylation (where SUMO indicates small ubiquitin-like modifier) of AR inhibits its transc

63 plex, a newly identified player in the SUMO (small ubiquitin-like modifier) pathway, led to increased

64 Post-translational modification by SUMO (small ubiquitin-like modifier) plays important but still

65 all of which are involved in conjugating the small ubiquitin-like modifier polypeptide, SUMO-1, to it

66 on that is balanced by the activity of ULP-4 small ubiquitin-like modifier protease.

67 c post-translational modification in which a small ubiquitin-like modifier protein (SUMO) is attached

68 ional modification of target proteins by the small ubiquitin-like modifier protein (SUMO) regulates m

69 The small ubiquitin-like modifier protein (SUMO) regulates t

70 ggesting that binding of Ubc9 and subsequent small ubiquitin-like modifier protein 1 (SUMO-1) modific

71 een CPEB3 RNA-binding domain (CPEB3-RBD) and small ubiquitin-like modifier protein 2 (SUMO2).

72 lating enzyme CgUlp2 leads to highly reduced small ubiquitin-like modifier protein levels, and impair

73 f the Snf1 catalytic subunt of SNF1 with the small ubiquitin-like modifier protein SUMO, catalyzed by

74 man histone H4 N-terminal tail region by the small ubiquitin-like modifier protein, SUMO-3, is associ

75 Conjugation of SUMO (Small Ubiquitin-like Modifier) protein to cellular targe

76 mediate both processing and deconjugation of small ubiquitin-like modifier proteins (SUMOs).

77 tly and reversibly on lysine residues by the small ubiquitin-like modifier proteins termed SUMOs.

78 slational modification of proteins by SUMOs (small ubiquitin-like modifier proteins; SUMOylation).

79 t-translational modification of TDG by SUMO (small ubiquitin-like modifier) reduces its glycosylase a

80 SUMO (small ubiquitin-like modifier)-specific proteases regula

81 ctive RNA polymerase I transcription and the small ubiquitin-like modifier-specific protease SENP3.

82 hird post-translational modification, by the small ubiquitin like modifier SUMO, is part of the same

83 udy, we have discovered a novel role for the small ubiquitin-like modifier SUMO in the regulation of

84 The small ubiquitin-like modifier SUMO regulates nuclear tra

85 We find that TBX22 is a target for the small ubiquitin-like modifier SUMO-1 and that this modif

86 isolated Ubc9, an enzyme that conjugates the small ubiquitin-like modifier SUMO-1.

87 TDP1 is a substrate for modification by the small ubiquitin-like modifier SUMO.

88 zed by immunofluorescence with antibodies to small ubiquitin-like modifier (SUMO) 1 localized to nucl

89 A small ubiquitin-like modifier (SUMO) acceptor site was r

90 Mms21 promotes cohesin-dependent small ubiquitin-like modifier (SUMO) accumulation at las

91 tification by mass spectrometry of a site of small ubiquitin-like modifier (SUMO) adduction, Lys-679

92 Dynamic modification of proteins with the small ubiquitin-like modifier (SUMO) affects the stabili

93 modification with one of the isoforms of the small ubiquitin-like modifier (SUMO) affects thousands o

94 4 ICD is posttranslationally modified by the small ubiquitin-like modifier (SUMO) and functionally in

95 .7 was enhanced by conjugation of CRMP2 with small ubiquitin-like modifier (SUMO) and further control

96 neering studies on the interplay between the small ubiquitin-like modifier (SUMO) and influenza A vir

97 es APB condensation via interactions between small ubiquitin-like modifier (SUMO) and SUMO interactio

98 Here, we identify MFF as a target of small ubiquitin-like modifier (SUMO) at Lys(151), MFF SU

99 nd proteomics data, Hsf1 is also modified by small ubiquitin-like modifier (SUMO) at several sites.

100 Remarkably, small ubiquitin-like modifier (SUMO) attenuates AR aggre

101 of TDG mutants defective for sumoylation and Small Ubiquitin-like Modifier (SUMO) binding and by alte

102 the ZZ zinc finger domain represents a novel small ubiquitin-like modifier (SUMO) binding motif.

103 The small ubiquitin-like modifier (SUMO) can form polymeric

104 ss the accumulation of high molecular weight small ubiquitin-like modifier (SUMO) conjugates.

105 unctional roles in SG disassembly, including small ubiquitin-like modifier (SUMO) conjugating enzymes

106 Small ubiquitin-like modifier (SUMO) conjugation also oc

107 Small ubiquitin-like modifier (SUMO) conjugation is a re

108 Posttranslational modification by small ubiquitin-like modifier (SUMO) conjugation regulat

109 The activity of STAT1 is inhibited by small ubiquitin-like modifier (SUMO) conjugation.

110 post-translational modifications, including small ubiquitin-like modifier (SUMO) conjugation.

111 ubiquitylation, methylation, acetylation and small ubiquitin-like modifier (SUMO) conjugation.

112 Small ubiquitin-like modifier (SUMO) conjugation/deconju

113 We show here that Cav-3 has a small ubiquitin-like modifier (SUMO) consensus motif (Ps

114 we report that SHMT1 is ubiquitinated at the small ubiquitin-like modifier (SUMO) consensus motif and

115 e show that lysine residues within conserved small ubiquitin-like modifier (SUMO) consensus sites in

116 sin response mediator protein 2 (CRMP2) by a small ubiquitin-like modifier (SUMO) could affect NaV tr

117 Small ubiquitin-like modifier (SUMO) covalently attaches

118 any RNA viruses were identified, such as the small ubiquitin-like modifier (SUMO) domain, phospholipa

119 study, we found that the SAE2 subunit of the small ubiquitin-like modifier (SUMO) E1 is autoSUMOylate

120 Hsp27 interacted physically with Ubc9, the small ubiquitin-like modifier (SUMO) E2 conjugating enzy

121 tin proteasome system, and expression of the small ubiquitin-like modifier (SUMO) E2 enzyme UBC9 impr

122 evidence establishes that AtSIZ1 is a plant small ubiquitin-like modifier (SUMO) E3 ligase and is a

123 In keeping with the small ubiquitin-like modifier (SUMO) E3 ligase function

124 hrough its chromodomain, Cbx4 functions as a small ubiquitin-like modifier (SUMO) E3 ligase in a SUMO

125 tion factor IIIA (TFIIIA) interacts with the small ubiquitin-like modifier (SUMO) E3 ligase PIAS2b an

126 ligase, we find that TIF1gamma operates as a small ubiquitin-like modifier (SUMO) E3 ligase that prom

127 re, we show that PIAS1, which functions as a small ubiquitin-like modifier (SUMO) E3 ligase, associat

128 vitro, demonstrating that E4-ORF3 acts as a small ubiquitin-like modifier (SUMO) E3 ligase.

129 Small ubiquitin-like modifier (SUMO) E3 ligases are know

130 The small ubiquitin-like modifier (SUMO) E3, RanBP2, confers

131 onoclonal antibodies (MAb) to members of the Small Ubiquitin-like modifier (SUMO) family are essentia

132 t-translational protein modifications by the small ubiquitin-like modifier (SUMO) family have been sh

133 , but not C/EBP beta-2, is conjugated to the small ubiquitin-like modifier (SUMO) family members, SUM

134 tional modification in which a member of the small ubiquitin-like modifier (SUMO) family of proteins

135 l to the recognition site for members of the small ubiquitin-like modifier (SUMO) family of ubiquitin

136 oylation involves activation and transfer of small ubiquitin-like modifier (SUMO) from the thioester

137 st-translational modification of proteins by Small Ubiquitin-like Modifier (SUMO) has been reported t

138 Dynamic modification involving small ubiquitin-like modifier (SUMO) has emerged as a ne

139 osttranslational modification of proteins by small ubiquitin-like modifier (SUMO) has received much a

140 Here, we report a novel role of small ubiquitin-like modifier (SUMO) in mTOR complex ass

141 s for the post-translational modification of small ubiquitin-like modifier (SUMO) in regulating the r

142 Here we report that BRCA1 is modified by small ubiquitin-like modifier (SUMO) in response to geno

143 Small ubiquitin-like modifier (SUMO) is a common post-tr

144 Posttranslational modification by small ubiquitin-like modifier (SUMO) is a major regulato

145 Small ubiquitin-like modifier (SUMO) is a member of the

146 ere we demonstrate that conjugation with the small ubiquitin-like modifier (SUMO) is a novel PTM requ

147 Small ubiquitin-like modifier (SUMO) is a peptide that c

148 Small ubiquitin-like modifier (SUMO) is a small protein

149 The small ubiquitin-like modifier (SUMO) is a ubiquitin-like

150 Here we report that the small ubiquitin-like modifier (SUMO) is conjugated (SUMO

151 The small ubiquitin-like modifier (SUMO) is covalently linke

152 Conjugation to the small ubiquitin-like modifier (SUMO) is emerging as an i

153 The small ubiquitin-like modifier (SUMO) is implicated in va

154 Small ubiquitin-like modifier (SUMO) is involved in vari

155 Post-translational modification by small ubiquitin-like modifier (SUMO) is one such possibl

156 osttranslational modification of proteins by small ubiquitin-like modifier (SUMO) is required for sur

157 In the final step of this process, the small ubiquitin-like modifier (SUMO) is transferred from

158 Small ubiquitin-like modifier (SUMO) is used by the intr

159 slational modification of ZBP-89 by multiple small ubiquitin-like modifier (SUMO) isoforms occurs at

160 , inhibiting its association with 7SK and E3 small ubiquitin-like modifier (SUMO) ligase activity on

161 single-strand binding protein POT-1, and the small ubiquitin-like modifier (SUMO) ligase GEI-17.

162 nction except for Nse2/Mms21, which is an E3 small ubiquitin-like modifier (SUMO) ligase important fo

163 This process is carried out by the E3-small ubiquitin-like modifier (SUMO) ligase protein inhi

164 ultiple subunits and identify SIZ1 as the E3 Small Ubiquitin-like Modifier (SUMO) ligase responsible

165 tein inhibitor of activated STAT1 (PIAS1), a small ubiquitin-like modifier (SUMO) ligase that regulat

166 hat the yeast proline isomerase Fpr3 and the small ubiquitin-like modifier (SUMO) ligase Zip3 ensure

167 transcription) RING domain characteristic of small ubiquitin-like modifier (SUMO) ligases, two struct

168 Dynamic small ubiquitin-like modifier (SUMO) linkages to diverse

169 ation Italian ringspot virus hijack the host small ubiquitin-like modifier (SUMO) machinery in yeast

170 The small ubiquitin-like modifier (SUMO) modification alters

171 Small ubiquitin-like modifier (SUMO) modification has em

172 UBC9 and was a substrate for UBC9-catalyzed small ubiquitin-like modifier (SUMO) modification in vit

173 ey mechanism by which this occurs is through small ubiquitin-like modifier (SUMO) modification of Maf

174 We recently described a critical role for a small ubiquitin-like modifier (SUMO) modification of NF-

175 Small ubiquitin-like modifier (SUMO) modification of pro

176 Small ubiquitin-like modifier (SUMO) modification of seq

177 Small ubiquitin-like modifier (SUMO) modification of tra

178 p14 Arf promotes small ubiquitin-like modifier (SUMO) modification of WRN

179 Small ubiquitin-like modifier (SUMO) modification regula

180 We show here that BLM is a substrate for small ubiquitin-like modifier (SUMO) modification, with

181 Posttranslational addition of a small ubiquitin-like modifier (SUMO) moiety (SUMOylation

182 lation of NRL in vivo and in vitro, with two small ubiquitin-like modifier (SUMO) molecules attached

183 In this context, small ubiquitin-like modifier (SUMO) often provides a bi

184 dified in vitro and in cultured cells by the Small ubiquitin-like modifier (SUMO) on two independent

185 Here, we show that hypoxia activates the Small Ubiquitin-like Modifier (SUMO) pathway in rat cere

186 Here, we show that the small ubiquitin-like modifier (SUMO) pathway is required

187 Here, we show the small ubiquitin-like modifier (SUMO) pathway modulates N

188 mber of the E3 ligase family involved in the small ubiquitin-like modifier (SUMO) pathway, we show fu

189 ue to a defect in a gene encoding a putative small ubiquitin-like modifier (SUMO) peptidase.

190 Protein modifications by ubiquitin and small ubiquitin-like modifier (SUMO) play key roles in c

191 Modification of proteins by small ubiquitin-like modifier (SUMO) plays an important

192 osttranslational modification of proteins by small ubiquitin-like modifier (SUMO) plays essential rol

193 In this study we show that the small ubiquitin-like modifier (SUMO) plays multiple role

194 The covalent attachment of small ubiquitin-like modifier (SUMO) polypeptides regula

195 ing evolution, the enzyme Ubc9 activates the small ubiquitin-like modifier (SUMO) prior to its covale

196 ve analyzed the mitotic function of SENP6, a small ubiquitin-like modifier (SUMO) protease that disas

197 Small ubiquitin-like modifier (SUMO) proteases are requi

198 Small ubiquitin-like modifier (SUMO) proteases regulate

199 Some of these genes encode small ubiquitin-like modifier (SUMO) proteases specific

200 In this study of two pore-associated small ubiquitin-like modifier (SUMO) proteases, sentrin/

201 eins both as targets for modification by the small ubiquitin-like modifier (SUMO) protein and as cata

202 The E3 small ubiquitin-like modifier (SUMO) protein ligase prot

203 this process, an extremely limited number of small ubiquitin-like modifier (SUMO) protein ligases (E3

204 a proportion of DELLAs is conjugated to the Small Ubiquitin-like Modifier (SUMO) protein, the extent

205 cation pathway catalyzing the conjugation of small ubiquitin-like modifier (SUMO) proteins (SUMO1, SU

206 Small ubiquitin-like modifier (SUMO) proteins act in DNA

207 Post-translational modifications by Small Ubiquitin-like Modifier (SUMO) proteins are involv

208 Conjugation by small ubiquitin-like modifier (SUMO) proteins at two syn

209 Conjugation of small ubiquitin-like modifier (SUMO) proteins has been s

210 t posttranslational modification of Kv1.5 by small ubiquitin-like modifier (SUMO) proteins modulates

211 Posttranslational modifications with small ubiquitin-like modifier (SUMO) proteins regulate m

212 tion characterized by covalent attachment of small ubiquitin-like modifier (SUMO) proteins to a lysin

213 Modification of TDG by small ubiquitin-like modifier (SUMO) proteins weakens it

214 ovalent modification of cellular proteins by small ubiquitin-like modifier (SUMO) proteins, regulates

215 tional modifications, such as conjugation of small ubiquitin-like modifier (SUMO) proteins.

216 e also been identified as E3 ligases for the small ubiquitin-like modifier (SUMO) proteins.

217 ls depends on their covalent modification by small ubiquitin-like modifier (SUMO) proteins.

218 Small ubiquitin-like modifier (SUMO) regulates diverse c

219 Post-translational modification by small ubiquitin-like modifier (Sumo) regulates many cell

220 karyotes, the conjugation of proteins to the small ubiquitin-like modifier (SUMO) regulates numerous

221 Structural studies of the E1 for the Ubl small ubiquitin-like modifier (SUMO) revealed a single a

222 of this particular antiviral response is the small ubiquitin-like modifier (SUMO) signaling pathway.

223 e IIalpha (TopoIIalpha), a major centromeric small ubiquitin-like modifier (SUMO) substrate.

224 enzyme with strict specificity for its plant small ubiquitin-like modifier (SUMO) substrates.

225 ols has allowed elucidation and study of the small ubiquitin-like modifier (SUMO) system in this unic

226 AAV transduction can be affected by the small ubiquitin-like modifier (SUMO) system, in which SU

227 Covalent attachment of the small ubiquitin-like modifier (SUMO) to key targets in t

228 jugating enzyme that transfers the activated small ubiquitin-like modifier (SUMO) to protein substrat

229 Conjugation of the small ubiquitin-like modifier (SUMO) to protein substrat

230 Sumoylation, a process of adding small ubiquitin-like modifier (SUMO) to proteins posttra

231 Attachment of the small ubiquitin-like modifier (SUMO) to substrate protei

232 how that MEL-18 is able to interact with the small ubiquitin-like modifier (SUMO) ubiquitin carrier p

233 The small ubiquitin-like modifier (SUMO), initially characte

234 When a transcription factor is modified by small ubiquitin-like modifier (SUMO), this usually repre

235 sites of post-translational modification by small ubiquitin-like modifier (SUMO), we have examined w

236 Here we demonstrate that small ubiquitin-like modifier (SUMO)- and folate-depende

237 global hyposumoylation and redistribution of small ubiquitin-like modifier (SUMO)-1 conjugates into d

238 n this study, we determined the occupancy of Small Ubiquitin-like MOdifier (SUMO)-1 on chromatin in H

239 t of Htt (Httex1p) can be modified either by small ubiquitin-like modifier (SUMO)-1 or by ubiquitin o

240 l 4,5-bisphosphate synthesis, is modified by small ubiquitin-like modifier (SUMO)-1.

241 Global increases in small ubiquitin-like modifier (SUMO)-2/3 conjugation are

242 We previously identified Arkadia as a small ubiquitin-like modifier (SUMO)-binding protein wit

243 The function of small ubiquitin-like modifier (SUMO)-binding proteins is

244 IE1 caused loss of the small ubiquitin-like modifier (SUMO)-conjugated forms of

245 Here, we show that UBC-9, the sole E2 small ubiquitin-like modifier (SUMO)-conjugating enzyme,

246 It required the small ubiquitin-like modifier (SUMO)-conjugating enzyme,

247 ntification of Ubc9 and PIASy, the E2 and E3 small ubiquitin-like modifier (SUMO)-conjugating enzymes

248 A scan for small ubiquitin-like modifier (SUMO)-interacting motifs

249 a conserved family of proteins that contain small ubiquitin-like modifier (SUMO)-like domains.

250 nts a class of ubiquitin ligases that target Small Ubiquitin-like Modifier (SUMO)-modified proteins f

251 Here, we identify a small ubiquitin-like modifier (SUMO)-specific protease (

252 on, we used de-SUMOylation enzyme of sentrin/Small Ubiquitin-like MOdifier (SUMO)-specific protease 2

253 Two Sentrin/small ubiquitin-like modifier (SUMO)-specific protease 7

254 s, both of which are implicated in ubiquitin/small ubiquitin-like modifier (SUMO)-targeted protein de

255 proliferating cell nuclear antigen (PCNA), a small ubiquitin-like modifier (SUMO)-targeted substrate,

256 Like the small ubiquitin-like modifier (SUMO)-targeted ubiquitin

257 we demonstrate that RNF4, a highly conserved small ubiquitin-like modifier (SUMO)-targeted ubiquitin

258 Here, we show that human RNF4, a small ubiquitin-like modifier (SUMO)-targeted ubiquitin

259 Although Slx5/Slx8 is a small ubiquitin-like modifier (SUMO)-targeted ubiquitin

260 posttranslational modification (PTM) by the small ubiquitin-like modifier (SUMO).

261 modification with the ubiquitin-like protein small ubiquitin-like modifier (SUMO).

262 validated substrates for modification by the Small Ubiquitin-like Modifier (SUMO).

263 role in cardiogenesis and is a target of the small ubiquitin-like modifier (SUMO).

264 to bind chromosomal proteins modified by the small ubiquitin-like modifier (SUMO).

265 IBDs and mouse models showed an increase in small ubiquitin-like modifier (SUMO)2 and SUMO3 during a

266 undergoes PML-dependent hyper-sumoylation by small ubiquitin-like modifier (SUMO)2/3 but not SUMO1, u

267 epression domain sequences contain sites for small ubiquitin-like modifier (SUMO)ylation, short inter

268 nal modifications, including acetylation and small ubiquitin-like modifier (SUMO)ylation.

269 tion and activity of CPEB3 are controlled by small ubiquitin-like modifier (SUMO)ylation.

270 nhibitory and transrepressor activities to a small ubiquitin-like modifier (SUMO-1) protein consensus

271 el mechanism of Sp1 regulation involving the small ubiquitin-like modifier (SUMO-1).

272 te that IE72 is covalently conjugated to the small ubiquitin-like modifier (SUMO-1).

273 ting macrophages, some IRF8 is conjugated to small ubiquitin-like modifiers (SUMO) 2/3 through the ly

274 Small ubiquitin-like modifiers (SUMO) are covalently con

275 ough post-translational modifications by the small ubiquitin-like modifiers (SUMO) are known to be im

276 t-translational protein modifications by the small ubiquitin-like modifiers (SUMO) have recently emer

277 lved the crystal structure of the E2 for the small ubiquitin-like modifiers (SUMO) in complex with an

278 demonstrate that protein modification by the small ubiquitin-like modifiers (SUMO) is a novel target

279 Using yeast two-hybrid screening, small ubiquitin-like modifiers (SUMO-1, SUMO-2, and SUMO

280 Here we show that tethering of a small, ubiquitin-like modifier (SUMO) moiety to p53 mark

281 The protein called 'small ubiquitin-like modifier' (SUMO) is post-translatio

282 nslational modification of substrates by the small ubiquitin-like modifier, SUMO, regulates diverse b

283 t-translational modification mediated by the small ubiquitin-like modifier, SUMO.

284 e we analyzed the modification of PKR by the small ubiquitin-like modifiers SUMO1 and SUMO2 and evalu

285 show that FXR is covalently modified by the small ubiquitin-like modifier (Sumo1), an important regu

286 Small ubiquitin-like modifier (SUMO1-3) conjugation (SUM

287 en for proteins binding noncovalently to the small ubiquitin-like modifier SUMO2.

288 cifically induces modification of Rta by the small ubiquitin-like modifiers SUMO2 and SUMO3.

289 , whether human septins could be modified by small ubiquitin-like modifiers (SUMOs) and what roles th

290 The mammalian small ubiquitin-like modifiers (SUMOs) are actively invo

291 The small ubiquitin-like modifiers (SUMOs) are posttranslati

292 Posttranslational modifications by small ubiquitin-like modifiers (SUMOs) regulate many cel

293 The small ubiquitin-like modifiers (SUMOs) regulate many ess

294 sttranslational modifications of proteins by small ubiquitin-like modifiers (SUMOs) regulate protein

295 sites and conjugates these proteins with the small ubiquitin-like modifiers (SUMOs) through its SUMO

296 The posttranslational addition of small ubiquitin-like modifiers (SUMOs) to other intracel

297 Posttranslational modification by small ubiquitin-like modifiers (SUMOs), known as SUMOyla

298 The covalent attachment of SUMO (small ubiquitin-like modifier) to other intracellular pr

299 We have previously described a role for the small ubiquitin-like modifier type 1 (SUMO-1) as a regul

300 orm-alpha (HSP90-SUMO1, where SUMO indicates small ubiquitin-like modifier), while no reactivity with