ライフサイエンスコーパス: solution structure

1 extent electrosprayed proteins retain their solution structure.

2 ESI process, rather than a genuine memory of solution structure.

3 toxins (TFT) or from the kappa-bungarotoxin solution structure.

4 rmations only slightly more compact than the solution structure.

5 mited degree of inter-SCR flexibility in its solution structure.

6 ns initially adopt their biologically active solution structures.

7 f very small transitions between crystal and solution structures.

8 he MD results and the experimentally derived solution structures.

9 antly improved our understanding of antibody solution structures.

10 at arise from a heterogeneous mixture of RNA solution structures.

11 Both a solution structure (2a) and a possible binding mode for

12 in (Ntd), which prompted us to elucidate the solution structure and activity of both the full-length

13 xperimental and computational studies on the solution structure and aggregation properties of both si

14 and potential function, we characterized the solution structure and binding distribution of the MBD3

15 The solution structure and dynamic ensembles of the duplexes

16 etic resonance spectroscopy to determine the solution structure and dynamic features of an Hsp40 in c

17 Here, we probe the solution structure and dynamics of active and inactive T

18 Here, we report the high-resolution solution structure and dynamics of such an active SCI.

19 The results provide insights into polyQ solution structure and fibril formation while also sugge

20 tational model to predict the large-scale 3D solution structure and flexibility of nucleic acid nanos

21 X-ray interferometry technique to probe the solution structure and fluctuations of B-form DNA on a l

22 search approach for getting insight into the solution structure and function of carbohydrates at all

23 Here we report the solution structure and in vitro activity for the cross-l

24 We report here the solution structure and mechanism of novel iron-mediated

25 The average solution structure and microscopic elasticity measured b

26 To probe the solution structure and oligomerization properties of HD5

27 PolyQ solution structure and properties are important not only

28 s indispensable for proper function, yet its solution structure and role in catalysis remain elusive.

29 Here, we present the high-resolution solution structure and structural dynamics of the D' reg

30 small angle neutron scattering to study the solution structure and subunit organization of a holoenz

31 diferric state does not represent the frozen solution structure and that a mono-mu-hydroxo diferrous

32 mall angle x-ray scattering to determine the solution structure and to analyze the conformational fle

33 nal studies shed light on the details of the solution structures and afford a highly predictive stere

34 Solution structures and biochemical data have provided a

35 s at very low temperatures aimed at defining solution structures and dynamics and some kinetic studie

36 We have determined the solution structures and thermodynamic properties of Baci

37 binding region that characterize its compact solution structure are diminished.

38 cesses, but their mechanisms of assembly and solution structures are difficult to define.

39 ons produced from modeling suggests that the solution structures are largely preserved in the gas pha

40 Here, we reveal the full ensemble of solution structures assumed by a model RNA HJH.

41 Here we present the first solution structures based on data from NMR spectroscopy

42 der what conditions, and to what extent, can solution structure be retained without solvent?"

43 g (SEC-SAXS) to analyze the full-length hPAH solution structure both in the presence and absence of P

44 binds to C3d and C3b, we determined the TT30 solution structure by a combination of analytical ultrac

45 e determined its monomeric three-dimensional solution structure by NMR and characterized its binding

46 Furthermore, its solution structure closely matched (backbone rmsd 1.21 A

47 The solution structure confirms that PASGtYybT adopts the ch

48 rearrangement of the active site, leading to solution structures consistent with available functional

49 tructures were compared to the corresponding solution structures derived from measured proton chemica

50 ormation, which is remarkably similar to its solution structure determined by NMR.

51 hia coli, solved by NMR, represent the first solution structures determined for the type III class of

52 ramolecular hydrogen bonding observed in the solution structures determined in the low-dielectric sol

53 It was found that the solution structure differs from the crystal structure in

54 We report the solution structure, dynamics, and energetics of three tr

55 ta are ubiquitous and most routinely used in solution structure elucidation, this fast and efficient

56 However, their solution-structure elucidation by NMR presents several c

57 ion and employ this to evaluate the accurate solution structure for each [LnL(1)].

58 We present the NMR solution structure for Escherichia coli DolP, which is c

59 Solution structures for antibodies are critical to under

60 g modeling revealed predominantly asymmetric solution structures for both antibodies with extended hi

61 cture was used to identify 10-12 near-planar solution structures for each of the MBL dimers, trimers,

62 ently used for heparin, we have analyzed the solution structures for eight purified HS fragments dp6-

63 tron scattering modeling revealed asymmetric solution structures for IgG4(Ser(222)) with extended hin

64 neutron scattering are techniques that give solution structures for large macromolecules.

65 eproducibly revealed very similar asymmetric solution structures for monomeric rabbit IgG in differen

66 can lead to disparities between gaseous and solution structures for partially unfolded proteins.

67 onductivity toward the identification of the solution structures formed when a range of carbonyl comp

68 actions were analyzed in the 113 crystal and solution structures from the lipocalin family.

69 We further report ComGC solution structures from two naturally competent human p

70 for MeTr and CFeSP both free and in complex, solution structures have not been established.

71 comparing the CCS of a ferritin cage to the solution structures in the PDB reveals significant devia

72 ects, particularly the relationships between solution structure, interfacial forces, and particle mot

73 The solution structure is an unusual H-type pseudoknot featu

74 The NDQ10 beta-sheet solution structure is essentially identical to that foun

75 The DQ10 PPII and 2.5(1)-helix solution structure is essentially identical to that in t

76 These near-planar fan-like solution structures joined at an N-terminal hub clarifie

77 Antigen solution structures, MAIT cell activation potencies (EC5

78 The methods developed here for N-mtMCM solution structure modeling should be suitable for other

79 1.25 A) crystal structure of proMPO and its solution structure obtained by small-angle X-ray scatter

80 Our solution structures obtained by small-angle X-ray scatte

81 NOE Rosetta program was used to generate the solution structure of a 27-kDa fragment of the Escherich

82 sing NMR methodology, we have determined the solution structure of a C-terminal fragment of eEF-2K, e

83 cinia graminis f. sp. tritici We present the solution structure of a coiled-coil (CC) fragment from S

84 Here, we report the NMR solution structure of a complex between PEP-19 and the C

85 present the first nuclear magnetic resonance solution structure of a DB[a,l]P-derived adduct, the 14R

86 altered recognition, we have determined the solution structure of a DNA duplex with a 5'CalphaAG-3'

87 Here we report on the NMR solution structure of a G-quadruplex formed by the CEB1

88 solved the high resolution three-dimensional solution structure of a Gla/Hyp-containing 18-residue co

89 Here, we investigated the solution structure of a minimal lambda5-UR motif that in

90 )-microglobulin (beta(2)m), to determine the solution structure of a nonnative amyloidogenic intermed

91 Here, we report the first NMR solution structure of a photoswitchable peptide derived

92 We reveal the solution structure of a short, antiparallel, myosin-10 c

93 The solution structure of a stabilized form of the active CP

94 Solution structure of AbpA determined by NMR reveals a n

95 Here, we examined the solution structure of AIPL1 by small angle x-ray scatter

96 Here, we present the solution structure of an analog of muO section sign-GVII

97 We report the solution structure of an autoinhibited NRD-TAD complex w

98 ts mainly in a monomeric form, we report the solution structure of an Hsp40 containing not only the J

99 This represents the first solution structure of an intercalated bis-ruthenium liga

100 We report on the first solution structure of an intramolecular G-quadruplex con

101 ing was used to determine the low resolution solution structure of apo-IRP1 and to characterize its b

102 ere we report the nuclear magnetic resonance solution structure of APOBEC3A and show that the critica

103 Here, we describe the NMR-derived solution structure of apoMlcB, which displays a globular

104 The solution structure of astexin-1 was determined revealing

105 ides, astexin-2 and astexin-3, and solve the solution structure of astexin-3.

106 The pseudo-atomic solution structure of BH0236 determined by small-angle X

107 Here, we determined the NMR solution structure of Blo t 21, which represents the fir

108 Here, we solved the solution structure of C. diphtheriae MsrB (Cd-MsrB) and

109 Here we present the solution structure of calcium-calmodulin bound to a pept

110 nding site on CCP 1 and visualized it with a solution structure of CCPs 1-3 derived by NMR and small

111 Here, we report the solution structure of CDK2AP1 by combined methods of sol

112 The solution structure of complement C3b is crucial for the

113 We have determined the solution structure of DBPA and studied DBPA's interactio

114 The solution structure of domains 18-19 showed a similar dom

115 We report the solution structure of Escherichia coli beta-galactosidas

116 Therefore, the solution structure of Escherichia coli TsaC was characte

117 and modeling clearly enabled us to infer the solution structure of FhaC, with H1 inside the pore as i

118 The solution structure of FhuA agrees with its crystal struc

119 esidues map to a beta-sheet in the published solution structure of FtsN(SPOR).

120 determined the small angle x-ray scattering solution structure of full-length IRF4, which, together

121 The NMR solution structure of HD5(ox), solved at pH 4.0 in 90:10

122 olipoprotein A-I plays a central role in the solution structure of high-density lipoproteins.

123 action between HMGA2 and RFs, we studied the solution structure of HMGA2, free and in complex with RF

124 Here we present the NMR solution structure of hMYDGF, which consists of a short

125 Here, we report the 3D NMR solution structure of homodimeric CC MBS in which amino

126 we have used NMR spectroscopy to obtain the solution structure of human DYNLT1 forming a complex wit

127 To this end, we determined the solution structure of human myeloma IgG2 by atomistic X-

128 The NMR solution structure of IreB was determined, revealing tha

129 The three-dimensional solution structure of KYE28 in LPS is characterized by a

130 Solution structure of LANA complexes revealed that while

131 We determined the solution structure of LEDGF PWWP and monitored binding t

132 The solution structure of LIMD2 that was determined using nu

133 To determine the solution structure of MBL, synchrotron x-ray scattering

134 Probing the solution structure of membrane proteins represents a for

135 We determined the solution structure of MOR, and we solved the crystal str

136 We have determined the solution structure of mouse IL-6 to assess the functiona

137 c basis for these differences, we solved the solution structure of MVN free and in complex with its l

138 Here, we present the First low resolution solution structure of myostatin-free and myostatin-bound

139 ication causes disease, we characterized the solution structure of native FHR5 by analytical ultracen

140 Finally, we also present the solution structure of OAS1 monomer and dimer, comparing

141 First, we solved the solution structure of OspE by NMR, revealing a fold that

142 Here, the solution structure of Pdc and its interaction with the 1

143 contrast variation was used to determine the solution structure of protein and lipid components of re

144 The aqueous solution structure of protoxin II (ProTx II) indicated t

145 The stability of the solution structure of rabbit IgG in different buffers an

146 Here we report the solution structure of RbpA and identify the principle si

147 The solution structure of Rbx1/ROC1 revealed a globular RING

148 The NMR solution structure of RD3 revealed an elongated backbone

149 We refined a three-dimensional solution structure of recombinant FH1-3 based on nuclear

150 However, the solution structure of recombinantly expressed and purifi

151 Here we report the solution structure of SecB, a chaperone that exhibits st

152 We report here the solution structure of several repetitive DNA sequences c

153 ction at a molecular level by solving both a solution structure of Sgt2_NT, which adopts a unique hel

154 Here, we report the solution structure of sigma1.1 from the Gram-positive ba

155 The nuclear magnetic resonance (NMR) solution structure of SpoIIID in complex with DNA reveal

156 We determined the NMR solution structure of the 1:2:1 parallel-stranded loop i

157 ere we report the nuclear magnetic resonance solution structure of the 2:1 complex of XR5944 with the

158 scattering studies allow for modeling of the solution structure of the activation domain in the absen

159 The three-dimensional NMR solution structure of the allosteric site revealed an al

160 conformational changes and report the first solution structure of the allosterically activated state

161 The three-dimensional solution structure of the alpha-conotoxin Lo1a was deter

162 Herein, we present the solution structure of the amino-terminal portion of mous

163 the high-affinity HM binding, we solved the solution structure of the apo form and the crystal struc

164 ce and SAXS data provided constraints on the solution structure of the aptamer and enable computation

165 ort the crystal structure and low resolution solution structure of the BARPH domains of APPL2.

166 We report the NMR-derived solution structure of the Brd4 ET domain bound to a cons

167 We have determined the solution structure of the C-terminal domain of human SRA

168 In addition, the dynamic 3D solution structure of the C-terminal heptapeptide of the

169 Here, we report the solution structure of the C-terminal zinc-binding domain

170 NMR spectroscopy, we have characterized the solution structure of the C-terminus of MBD1 (MBD1-c, re

171 Here we present and interpret the solution structure of the C-type lectin-like domain of N

172 A low-resolution solution structure of the closed conformation of PKCbeta

173 Here we describe the solution structure of the complex formed by the interact

174 The solution structure of the complex of enzyme IIA of the N

175 The solution structure of the construct was determined in do

176 We reevaluated the solution structure of the CR2-C3d complex that confirmed

177 This binding surface can accommodate the 3D solution structure of the cross-linked cell wall.

178 The NMR solution structure of the CTD indicates it is a vestigia

179 xperimental studies are yet to determine the solution structure of the Cu site and how this relates t

180 The NMR solution structure of the d(TTGTGGTGGGTGGGTGGGT) sequenc

181 binding sites (EBS1 to -3).We solved the NMR solution structure of the d3' hairpin of the Sc.ai5gamma

182 ance (DEER) measurements to characterize the solution structure of the detergent-solubilized multidru

183 In this work, the solution structure of the deuterated Ca(2+)-CIB1 protein

184 Here we present the NMR solution structure of the Drosophila Smo CRD, and descri

185 tidine phosphotransfer (DHp) domains and the solution structure of the entire cytosolic domain of ETR

186 ts these perturbations to be mapped onto the solution structure of the enzyme.

187 We have determined the solution structure of the FliT chaperone in the free sta

188 ils of this activity, we have determined the solution structure of the Fpr4 C-terminal PPIase domain

189 ural changes upon binding, we determined the solution structure of the free dsRBD used in the previou

190 report the nuclear magnetic resonance (NMR) solution structure of the full-length CR4/5 domain from

191 Here, we report a solution structure of the full-length human Orc6 (HsOrc6

192 ufficient for interaction and solved the NMR solution structure of the globular domain of M2AP.

193 We elucidated the NMR solution structure of the GluC-digested peptide, OlvA(BC

194 Here, we describe the high-resolution solution structure of the Gp2-Ec beta' jaw domain comple

195 , we present unprecedented insights into the solution structure of the Hauser base (i)Pr2NMgCl 1 and

196 tivity by cAMP/TRIP8b, we determined the NMR solution structure of the HCN2 channel CNBD in the cAMP-

197 Here we report the solution structure of the Hox homeodomain in complex wit

198 Here, we report the solution structure of the HR domain of OutC and explore

199 The nuclear magnetic resonance (NMR) solution structure of the I domain revealed the presence

200 LTag hexameric helicases, we determined the solution structure of the intact hexameric E1 helicase b

201 we have determined the three-dimensional NMR solution structure of the intracellular domain of p45 an

202 t the use of NMR spectroscopy to analyze the solution structure of the isolated regulatory domain of

203 Here we provide the solution structure of the latter component of the RelA:C

204 sion proteins in leukemia, we determined the solution structure of the MLL-IBD complex.

205 Unexpectedly, the solution structure of the most potent stapled peptide, D

206 We determined the solution structure of the myristoylated protein and foun

207 port on the nuclear magnetic resonance (NMR) solution structure of the N-terminal domain of betaGRP (

208 he present study, we have determined the NMR solution structure of the N-terminal ectodomain of human

209 In this work we determined the solution structure of the N-terminal portion of the MCM

210 pling (RDC) measurements to characterize the solution structure of the non-glycosylated form.

211 The solution structure of the NOXO1beta PX domain shows grea

212 Here we present the solution structure of the NPM1-C70 domain and NMR analys

213 g and x-ray crystallography, we describe the solution structure of the oligomers formed during the ir

214 The low-resolution solution structure of the open Munc18:Syntaxin binding m

215 We determined the solution structure of the PAS domain of GtYybT from Geob

216 show that IcsA is monomeric and describe the solution structure of the passenger domain obtained by s

217 Herein, we present the NMR solution structure of the phylogenetically conserved ISS

218 The solution structure of the reduced form of the MAL TIR do

219 A solution structure of the relevant LIP5-CHMP5 complex re

220 Therefore, here we investigated the solution structure of the retinoschisin monomer and the

221 We report here the solution structure of the RNA recognition motifs (RRM) d

222 Here we solve the solution structure of the RNF126 zinc finger domain in c

223 nformation compared to the unbound NMR-based solution structure of the same PG-fragment.

224 single-molecule FRET, we determined a novel solution structure of the single-nucleotide-gapped DNA-P

225 Furthermore, the solution structure of the switch I region is analyzed by

226 cale reagent synthesis and also predicts the solution structure of the ultimate organozinc reagent.

227 Here, we present the solution structure of the VWF C4 domain, which binds to

228 The NMR solution structure of the zinc-finger (ZnR) domain from

229 an inferred PREVIOUSLY: Here we describe the solution structure of the ZmPPR10: ATPH: complex using s

230 nsemble modeling analysis to investigate the solution structure of these linkers, extending from the

231 In this study, the solution structure of this domain was determined by smal

232 This is the first solution structure of this domain, and our investigation

233 lations show the B/P pair in the most stable solution structure of this FLP to have an unfavorable or

234 pe reconstruction provides insights into the solution structure of this previously unreported complex

235 The NMR solution structure of this trimeric domain, designated g

236 Here, we present the solution structure of TpbA in the ligand-free open confo

237 The NMR solution structure of TriA1 in dodecylphosphocholine mic

238 small-angle X-ray scattering to examine the solution structure of Trim5alpha BCC, the dimerization d

239 utron scattering (SANS) is used to probe the solution structure of two protein therapeutics (monoclon

240 hroughput scattering methods, we studied the solution structure of wild-type IgG4(Ser(222)) and a hin

241 The solution structure of YAP WW2 confirms that it has a can

242 structural motifs to predict the equilibrium solution structures of 45 DX-based DNA origami nanoparti

243 opy is used in this work to characterize the solution structures of bound anion receptors for the fir

244 Here, we present the solution structures of GDP-bound and apo-IF2-G2 of Bacil

245 The solution structures of Hbl, and Niby and Nibl, were char

246 ailed insights from single-crystal X-ray and solution structures of Hby have revealed a distorted hel

247 The solution structures of highly active Ir water-oxidation

248 Here, we provide the solution structures of its two RNA recognition motifs (R

249 f NADPH, we have determined and compared NMR solution structures of L. casei apo DHFR and its binary

250 scopy (cryo-EM) to study the high-resolution solution structures of murine norovirus as a model for h

251 We have concatenated new high-resolution solution structures of overlapping recombinant CCP pairs

252 Here we report the use of solution structures of Pol X in the free, binary (Pol X:

253 N in the absence or presence of RNAP and the solution structures of RapA and RapADeltaN either ligand

254 directed spin labeling was used to probe the solution structures of REs involved in p53 regulation of

255 The NMR solution structures of several of the monosaccharide-con

256 Analysis of crystal and solution structures of several of the products reveal th

257 SAXS solution structures of SNX20 and SNX21 show that these p

258 In this article, we present the crystal and solution structures of the 195-kDa C4b.

259 We determined the solution structures of the 1:1 and 2:1 BMVC-MycG4 comple

260 The solution structures of the 34-kDa apo- and holo-FepB fro

261 report the nuclear magnetic resonance (NMR) solution structures of the A20-like zinc finger (A20 Znf

262 nts applied toward the identification of the solution structures of the active Fe(III) and Ga(III) ca

263 tructures of the ASL(Arg1,2) showed that the solution structures of the ASLs were nearly identical.

264 The solution structures of the dilithiated diamino diethers

265 ic labeling ((2)H and (13)C) has allowed the solution structures of the freely exchanging major and m

266 used small-angle X-ray scattering to obtain solution structures of the full-length proteins and a se

267 the expected alpha-beta-alpha fold, but the solution structures of the major conformation of Nhp2p w

268 Furthermore, solution structures of the MLL3 core complex assembled w

269 scattering data, we report the pseudoatomic solution structures of the monomer and dimer forms of th

270 We report the first solution structures of the mouse Rev1 CTD and its comple

271 The solution structures of the phosphorylated and unphosphor

272 Solution structures of the proteins are based on NMR dat

273 Here we report crystal and solution structures of the resting and activated states

274 We solved the solution structures of the RRM in complex with poly(U) o

275 Here, we describe the solution structures of the two central complexes of the

276 Here, crystallographic and solution structures of the UVR8 homodimer, together with

277 We report the solution structures of the VPg proteins from feline cali

278 The solution structures of three mixed aggregates dissolved

279 Solution structures of two complexes, both comprised of

280 To rectify this, we have studied the solution structures of two human IgG1 6a and 19a monoclo

281 This article reports the NMR solution structures of two N-terminally extended mycolac

282 The solution structures of Znby and Znbl were studied by NMR

283 Crystal and solution structures plus mutations characterize alternat

284 contrast to other reported PDZ domains, the solution structure previously reported for IL-16 reveals

285 The binding interfaces from the two solution structures provide useful information for speci

286 The resulting asymmetric IgG1 solution structures resembled its crystal structure.

287 ermined by small-angle x-ray scattering, the solution structures reveal a new conformation of RapA, d

288 he NMR-restrained molecular-dynamics-derived solution structure revealed that the modifications provi

289 ized and characterized in terms of their NMR solution structures, serum and thermal stabilities, and

290 The solution structures, stabilities, physical properties, a

291 tion W165T causes destabilization of protein solution structure, strongest for domain D1, which inter

292 To reveal its solution structure that underlies such a dynamic and com

293 In X-ray solution structures, the CARDs in unliganded MDA5 are fl

294 of Bc28.1 and determined its high resolution solution structure using NMR spectroscopy.

295 pressed and purified to homogeneity, and its solution structure was found to be dimeric.

296 Based on NMR and CD data, its solution structure was solved and is a long bent, interr

297 triplex maintains an excellent memory of the solution structure, well-preserved helicity, and a signi

298 Solution structures were determined by NMR, activity ass

299 Both symmetric and asymmetric solution structures were determined for IgG4.

300 (octapa)](-) complex revealed a 7-coordinate solution structure, which forms a single isomer and exhi