ライフサイエンスコーパス: sought-after

1 s pores to produce the heterogeneity that is sought after.

2 become that enabling technology for so long sought after.

3 facilitate global glycan analysis are highly sought after.

4 be expanded for clinical benefit are highly sought after.

5 mple or a plant extract is therefore largely sought after.

6 of proteins under mild conditions are widely sought after.

7 high efficacy and low toxicities are highly sought after.

8 and practical fluorination reactions remain sought after.

9 directly at reducing stress should rather be sought after.

10 rate clinical contexts and thus are globally sought after.

11 them in a stereoselective fashion are highly sought after.

12 Counteracting strategies are thus heavily sought after.

13 dentified but key downstream proteins remain sought after.

14 argeting while saving normal tissue are much sought after.

15 ethods for carbon dioxide capture are highly sought after.

16 compounds with these motifs are desired and sought after.

17 ials for preparing fine chemicals are highly sought after.

18 nt strategies for their synthesis are highly sought after.

19 um salt derivatives have become increasingly sought after.

20 vity with isotopic discrimination are highly sought after.

21 tronic materials, benzothiophenes are highly sought after.

22 es complement activation and CDC, are highly sought after.

23 lectively and/or enantioselectively are much sought after.

24 ynthesis from chemical feedstocks are highly sought after.

25 t can oxidize succinyl-CoA to fumaryl-CoA is sought after.

26 rupt this signaling pathway have been highly sought after.

27 energy-efficient cooling methods are highly sought-after.

28 complex structures, have become increasingly sought-after.

29 potent antileishmanial activities is highly sought-after.

30 ngth and ductility is challenging yet highly sought-after.

31 s, which thrive in hostile environments, are sought-after.

32 versatile route for the synthesis of highly sought after 1,2,4-trisubstituted arenes.

33 Broadly neutralizing HIV antibodies are much sought after (a) to guide vaccine design, both as templa

34 suggest that Ded1p may be a part of the long sought after activity shown to promote yeast viral dsRNA

35 on, "How old is a fingerprint?", is a highly sought-after aim in forensic science.

36 nthesize a fluorinated polyacetylene, a long-sought-after air-stable polyacetylene that has eluded sy

37 et al. and Renton et al.) show that the long sought after ALS/FTD mutation on chromosomal region 9p i

38 A sought-after alternative to haphazard molecular modulati

39 Its exact mode of action has long been sought after and is still being debated, with prevailing

40 Broad-spectrum antivirals are highly sought after and studied because they target common comp

41 t 2,5-aryl-substituted thiophenes are highly sought-after and that aryl substitution at the 3 and 4 p

42 provide experimental confirmation of a long sought after animal model of HDFN.

43 RAS, one of the most prevalent oncogenes and sought-after anticancer targets, has eluded chemists for

44 on in the KRAS gene making it among the most sought-after anticancer targets.

45 nt p53 using small molecules has been a long sought-after anticancer therapeutic strategy.

46 ne with functionalized co-monomers is a long-sought-after approach to introducing polyolefin function

47 coffee, and cacao are widely traded and much sought after around the world.

48 cell populations, which are being intensely sought after as a protective mechanism against endocrine

49 e-crystalline graphene monolayers are highly sought after as an ideal platform for electronic and oth

50 st on-demand single photon sources have been sought after as critical components of quantum informati

51 Near-infrared (NIR) probes are highly sought after as fluorescent tags for multicolor cellular

52 erved property of single crystals, is highly sought after as it enables crystal application in innova

53 s with a Kitaev spin liquid ground state are sought after as models of quantum phases but candidates

54 GalT inhibitors are therefore sought after as potential lead compounds for drug discov

55 and their facile fabrication have been long sought after as they promise to offer substantial improv

56 of its pH-activated function, GALA has been sought-after as a component of intracellular drug delive

57 arbon bonds in synthetic polymers are highly sought-after as they may provide tools for environmental

58 , we present high-confidence models of three sought-after assemblies formed by eight members of this

59 In contrast, when the sought-after assortative community structure is not stro

60 s, thus enabling rapid library generation of sought-after BCP derivatives for drug development.

61 smembrane aspartic proteinase to be the long sought after beta-secretase.

62 atory microRNAs could serve as promising and sought-after biomarkers of endometrial receptivity, fert

63 nthetically regulating kinases are thus much sought after, both for dissecting cell signaling pathway

64 These axially-chiral structures are much sought-after building blocks for CAS, but they were not

65 The long sought after but elusive efficient and selective oxygena

66 m, and ultrafast temporal duration, the long sought after but hitherto unrealized quest for ultrafast

67 structions of terrestrial climate are highly sought after but rare, particularly in Australia.

68 s) from renewable cell types has been a long sought-after but elusive goal in regenerative medicine.

69 anoactuators and nanomachines have long been sought after, but key bottlenecks remain.

70 They are clinically effective and highly sought-after, but have thus far only been discovered ser

71 esting is becoming more widely available and sought after by clinicians and patients alike, it is onl

72 onal group interconversions are particularly sought after by medicinal chemists as a means to enable

73 ts on this critical time-scale, while highly sought after by stakeholders, have yet to materialise.

74 considered an excellent source of nutrients, sought after by the food, nutraceutical and pharmaceutic

75 methods to address this challenge are highly sought after by the pharmaceutical industry.

76 ategy to treat metabolic disorders is highly sought after by the pharmaceutical industry.

77 ce presented here establishes PilZ as a long sought after c-di-GMP-binding domain and YcgR as a c-di-

78 spholipase C (PLC), PLCzeta, may be the long sought after [Ca2+]i oscillation-inducing SF.

79 ively underexplored, make peptide dendrimers sought-after candidates for various applications.

80 at the nanoscale is an essential and highly sought-after capability.

81 nal limit(3,12), but also establishes a long-sought-after carbon-based ferromagnetic transport channe

82 The structure reveals the long-sought-after catalytic Phi-clamp and the membrane-spanni

83 e (COD) or norbornadiene (NBD), yielded long sought-after cationic bis(phosphine) cobalt complexes, [

84 rol organ size and may, in fact, be the long sought after chalones, or negative growth regulators.

85 sults indicate that TORC2 is one of the long sought after cofactors that mediates the differential ef

86 Seafood is a highly traded and sought after commodity on international markets, and is

87 New N-heterocyclic fluorophores are sought-after compounds for organic electronic devices.

88 igence tools applied to the discovery of the sought-after comprehensive limb regeneration models.

89 tification, and characterization of the long sought-after Criegee intermediate for each system, as we

90 These findings identify a long-sought-after critical component of the nephron stem cell

91 he inter-configuration lines that reveal the sought-after crossing.

92 ally and thermally stable, yet have the long-sought-after design flexibility offered by functionalize

93 ium chloride showed them to contain the long sought-after dialuminene Ar(iPr8)AlAlAr(iPr8) (1) that f

94 not BH3-only proteins or p53/Rb, is the long-sought-after direct activator of Bax/Bak following BH3-o

95 ing the origin of turtles are among the most sought-after discoveries in palaeontology.

96 is important work not only identifies a long-sought-after dorsalizing factor but also highlights the

97 le in bone remodeling and for being a highly sought-after drug target for the treatment of osteoporos

98 pase family of cysteine proteases are highly sought-after drug targets owing to their essential roles

99 ems using machine learning has become highly sought after due to its potential applications in predic

100 r several decades and continues to be highly sought after due to the advent of targeted needle-free t

101 IMPORTANCE HIV cure is sought after due to the prevalence of comorbidities that

102 resulting in strong disorder that masks the sought-after effects.

103 y single-photon detectors are among the most sought-after elements in modern quantum optics and quant

104 Moire metrology establishes sought after experimental benchmarks for interlayer inte

105 that of Ni(II) complexes, serves as the long-sought-after experimental support for the proposed mecha

106 stringent conditions for achieving the long sought-after exponential selectivity using porous two-di

107 Thus, we propose that PARI is a long sought-after factor that suppresses inappropriate recomb

108 IM3 recently has been identified as the long-sought-after FcR for IgM (FcmuR).

109 A much-sought-after feature is the ability to turn off the dyna

110 to be clarified, acidity is one of the main sought-after features in coffee and it is becoming one o

111 generation and characterization of the long sought after ferriheme peroxynitrite complex has been ac

112 III)Dy(III)6} complex that exhibits the much sought-after ferrotoroidic ground state with an enhanced

113 ance raised the possibility that IL-33 was a sought after fibroblast-derived factor that promotes try

114 and travel rigidly in free space, are a long sought-after field structure with applications ranging f

115 le precursors successfully produced the long-sought-after first two examples of binary mixed-valent s

116 Using this approach, we discovered the long sought after folic acid receptor, fAR1, in D. discoideum

117 Honey and other bee products were likely a sought-after foodstuff for much of human history, with d

118 ectrometers with ever-smaller footprints are sought after for a wide range of applications in which m

119 apacitors with ultrahigh power densities are sought after for advanced electronic and electrical syst

120 Dual proton-electron conductors are highly sought after for applications in electronics and energy

121 circularly polarized light (CPL) are highly sought after for applications ranging from efficient dis

122 Top-level piscivores are highly sought after for consumption in freshwater fisheries, ye

123 at or below the single cell level is highly sought after for correlating the location of metal conta

124 nelle-specific nanocarriers (NCs) are highly sought after for delivering therapeutic agents into the

125 s emitting in the terahertz range are highly sought after for fundamental research and applications.

126 rganized soft materials are currently highly sought after for fundamental scientific studies and tech

127 ring (SERS) detection platform has long been sought after for low cost, rapid, and on-site detection

128 ge of interesting properties that are highly sought after for many applications.

129 or for Heptosyltransferase I (HepI) has been sought after for many years because of its critical role

130 Although CSL was highly sought after for more than twenty years, it had never be

131 ct the self-assembly of particles are highly sought after for multiple applications, including photon

132 Materials that bind metal cations are highly sought after for new devices.

133 Nucleic acid hybridization probes are sought after for numerous assay and imaging applications

134 ew of pathogen evolution and is increasingly sought after for outbreak surveillance.

135 s for protein biomarker detection are highly sought after for point of care applications.

136 arenes in a site-selective manner are highly sought after for rapidly constructing value-added molecu

137 Needle-free drug delivery is highly sought after for reduction in sharps waste, prevention o

138 iodic unsaturation in the backbone chain are sought after for synthesizing chemically recyclable poly

139 f biomimetic helical secondary structures is sought after for the construction of innovative nanomate

140 Broad-spectrum resistance (BSR) is highly sought after for the effective management of crop diseas

141 us time-reversal ( T ) symmetry breaking are sought after for their anomalous physical properties, lo

142 ptidic ligands is difficult, though they are sought after for their modularity and biocompatibility.

143 Compounds which release H2S slowly are sought after for their potential in therapy.

144 Multi-patch particles are highly sought after for their potential to present multiple dis

145 Laser-based displays are highly sought after for their superior brightness and colour pe

146 Nonribosomal peptides are highly sought after for their therapeutic applications.

147 ompounds play to achieve the characteristics sought after for TTA-UC.

148 harge switching mechanism, a property highly sought-after for biological applications.

149 lized piperidines, molecules that are highly sought-after for the synthesis of pharmaceuticals and ag

150 stems with three oxidation states are highly sought-after, for example, for redox-flow battery applic

151 eakfast sites with very ephemeral and highly sought-after fruit, like figs, than sites with less ephe

152 Our work elucidates the long-sought-after function of SNC1 in defense, and also how p

153 Our work uncovers the long-sought-after function of Zpr1 as a bespoke chaperone tai

154 SSM electrophysiology provides a long-sought-after functional assay for the ubiquitous ammoniu

155 formation via amorphous precursors is a long-sought-after gateway to engineer nanoparticles with well

156 regeneration in higher vertebrates is a long sought after goal in neuroscience.

157 ay take us one large step closer to the long sought after goal of separating GVL and GVHD.

158 on centers using catalysis has been a widely sought after goal, but complexes of highly substituted c

159 ility upon amino acid substitution is a much sought after goal.

160 exome sequencing (WES) data has been a long sought-after goal for use in clinics.

161 luripotent stem cells (PSCs) has been a long-sought-after goal for use in hematopoietic cell producti

162 after serial DENV infections has been a long-sought-after goal for vaccination.

163 (so-called mutant reactivation) is a highly sought-after goal in cancer drug development.

164 rather than by serendipity, has been a long sought-after goal in condensed matter physics and materi

165 ources and atomic quantum memories is a long sought-after goal in photonic quantum technologies.

166 to create nanostructured surfaces is a much sought-after goal in the SERS community.

167 One commonly sought-after goal is the creation of high aspect-ratio m

168 A long-sought-after goal is to achieve complementary absorption

169 Thus, targeting RAS remains a highly sought-after goal of cancer research.

170 me-like catalysts by design have been a long sought-after goal of chemists but difficult to realize d

171 n distributions in intact tissue is a highly sought-after goal, as it would provide visualization in

172 ns problematic for obligates and is a highly sought-after goal.

173 One of the long-sought-after goals in light manipulation is tuning of tr

174 er in its earliest stages is one of the most sought-after goals in medicine.

175 , RNASEL, as a strong candidate for the long sought after hereditary prostate cancer 1 (HPC1) allele.

176 electrons-a mechanism analogous to the long sought-after Higgs mechanism in particle physics.

177 In essence, phosphorene represents the much sought after high-mobility, large direct band gap two-di

178 sing waste lignocellulosic biomass to widely sought-after high surface area activated carbon and subs

179 enhouse effect, which may represent the long-sought-after historical analog to the carbon dioxide-ind

180 ka honey is New Zealand's (NZ) most globally sought-after honey variety, due to the bioactive effects

181 ns in the CB1 receptor, including the highly sought after hydrophobic pocket important for the bindin

182 overall costs are minimized, remain a highly sought-after ideal.

183 fore, pHLA-target Ags may represent the long sought-after, ideal targets for solid tumor targeting by

184 fects in oncology, and it is one of the most sought after immunotherapies for tumors.

185 natural photosynthetic systems and are also sought after in artificial systems as well.

186 p routine biological processes are very much sought after in bio-medical research.

187 potency and specificity and are increasingly sought after in drug discovery.

188 ernal surface areas, an asset that is highly sought after in material design, has brought metal-organ

189 ncrease molecular diversity, which is highly sought after in medicinal chemistry.

190 can dynamically manipulate light are highly sought after in modern optics and nanophotonics.

191 ultilplexed protein assays, which are highly sought after in molecular diagnostics such as cancer dia

192 An effective preventive vaccine is highly sought after in order to stem the current HIV-1 pandemic

193 eral possible beam shapes), which are highly sought after in the fields of optical trapping, biologic

194 to a wide range of oligomers that are highly sought-after in numerous fields to be controlled.

195 ns in a benign and precise manner are highly sought-after in protein science.

196 eightened tendency to encode and retain such sought-after information.

197 g Abeta species that is most likely the long sought after intermediate product, Abeta(49), generated

198 The key to this lies in solving the highly sought-after intermediate A(2/3)FePO4 (A = Na, Li) super

199 ile the two peroxide oxygens can undergo the sought after internal rotation.

200 The long sought-after, intrinsically short-lived molecule ethylen

201 rom Pyrococcus furiosus (PfMATE) in the long-sought-after inward-facing state, which was obtained aft

202 available in online repositories, offer the sought-after key for accelerated discovery of metallic g

203 hat, with continued study, might reveal long-sought-after keys to achieving CNS repair.

204 tures, such as diamond, pyrochlore and other sought-after lattices, have eluded self-assembly.

205 esidues as sites potentially involved in the sought after ligand-receptor interactions.

206 It may be the long sought after m-FSHRF.

207 cated roles for a new protein PIEZO1, a long sought after mammalian mechanosensory protein; GLUT1, th

208 h bioinformatics analysis could lead to much-sought-after markers of protective vaccination responses

209 sponses and are being championed as the long-sought-after mechanism for host-induced gene silencing.

210 en MSK1, Trim7 and RACO-1 completes the long sought-after mechanism linking growth factor signalling

211 tructures in mutagenesis and reveal the long-sought-after mechanism of complex mutations that represe

212 velopmental signals but also identify a long-sought-after mechanism that initiates Pax6 in placode pr

213 nowledge and reverse-engineering of the much sought-after mechanistic models in planaria and other re

214 We propose that md-L neurons are long sought after mechanoreceptor cells through which food me

215 mune cells with immunosuppressants is a much sought-after modality for the treatment of systemic lupu

216 ally unstable LBR variants may serve as long-sought-after model substrates enabling previously imposs

217 irocyclic molecules have become increasingly sought-after moieties in drug discovery.

218 methyl-substituted carbon centers are highly sought-after moieties in pharmaceutical and agrochemical

219 for the male-determining gene, but the much sought after molecular pathway that connects the gene to

220 kers (Cell Rep., 2019) have generated a long sought-after molecular atlas of vagal afferents in the m

221 strained proximity and stoichiometry for the sought-after molecular coupling.

222 a ubiquitinated nucleosome provide the long-sought-after molecular mechanism of Dot1L-mediated methy

223 tional repression of 15-PGDH elucidates long sought-after molecular mechanisms that govern PG action

224 Macrocyclic peptides are sought-after molecular scaffolds for drug discovery, and

225 Therefore, they have also been sought-after molecular targets for pharmacological inter

226 provide a platform for the design of a long sought after monovalent form of avidin, which would be i

227 A single-molecule electret is a long-sought-after nanoscale component because it can lead to

228 One long-sought after nanotechnology is systems able to achieve t

229 These data provide long sought after near-atomic resolution insights into how MA

230 t are missing in chicken, including the long-sought-after nephrin and tumor necrosis factor genes.

231 ediates proposed for ACS, including the long sought-after Ni(methyl)(CO) species, and promotes all ke

232 study demonstrates the accessibility of long-sought-after nickel(IV) intermediates in C-H functionali

233 ker research and discovery has been a highly sought-after objective.

234 nown for producing one of most expensive and sought-after oils in the world.

235 This behaviour remains highly sought after on polymeric surfaces as a means to expedit

236 se results provide support for DEK as a long sought-after oncogene mapping at chromosome 6, with nove

237 f the apoptotic machinery, and reveal a long sought-after oncogenic event conferring sensitivity to p

238 cal catalysts for these processes are highly sought after, only one enzyme that can convert fluoride

239 pproaches that target delirium might offer a sought-after opportunity for early intervention, preserv

240 These findings not only identify the long-sought-after osteoclast progenitors but also establish u

241 of EcNhaA, we sample what could be its long-sought-after outward-facing conformation and verify it u

242 patterns, V4 develops a selectivity for the sought-after pattern, which it does not manifest in a ta

243 Arabidopsis thaliana UVR8 (AtUVR8) is a long-sought-after photoreceptor that undergoes dimer dissocia

244 by the present study, point toward the long sought after physiological and pathophysiological roles

245 tably at room temperature are among the most sought-after platforms because such cells take advantage

246 er technology by targeting one of the highly sought-after POPs, for the first time ever recorded.

247 aterial class has the potential to merge the sought-after properties of complex oxides with electroni

248 m statistical mechanics and can thus exhibit sought-after properties such as autonomous motility, int

249 nic and inorganic semiconductors is a widely sought after property, but has so far been limited to th

250 emission color of functional materials is a sought-after property in many contexts.

251 IKK turns out to be the long-sought-after protein kinase that mediates the critical r

252 Here, we demonstrate that TMEM16F, the long-sought-after RBC CaPLSase, is activated by calcium influ

253 A long-sought-after reactive monophosphine-ligated palladium(0)

254 simulations identify the origin of this long sought-after regime as a planar, torsion-free backbone c

255 chinensis and Dalbergia oliveri are the most sought-after rosewoods in the Greater Mekong Subregion.

256 3D nanoporous nitrogen-doped graphene as the sought-after scaffold material for lithium anodes is rep

257 Therefore, Cyclin B1 is the long-sought-after scaffold that links MAD1 to the corona, and

258 ations are an important subclass, leading to sought-after scaffolds, but typically suffer from tailor

259 egakaryocytes, making it a candidate for the sought-after second platelet thrombin receptor.

260 t multiple proteinopathies, revealing a much-sought-after, shared therapeutic target across a broad r

261 which lead to intrinsic noise exceeding the sought-after signal from individual molecules, usually b

262 thiolate-for-thiolate exchange of the highly sought after silver molecular nanoparticle [Ag44(SR)30](

263 uce a variety of these azasugars are eagerly sought after, since even minute structural or stereochem

264 nclude that these cells are likely to be the sought-after SLCs.

265 ey work, and are these therapeutics the long-sought-after solution to obesity?

266 3:E2~Ub ligase complex and identify the long sought-after source of allostery for RING/U-Box activati

267 is) is one of the most culturally iconic and sought-after species by wildlife tourists.

268 amin B is a structural component of the long-sought-after spindle matrix that promotes microtubule as

269 cific immune tolerance to grafts remains the sought-after standard following transplantation.

270 s a radical fragmentation pathway delivering sought-after stereodefined 1,2-syn-hydroxy nitrile deriv

271 Our study essentially identifies a long-sought-after structural glass order in hard-sphere glass

272 ave a tangible probability to deliver a long-sought-after successful immune-targeted treatment for T1

273 n this privileged unit, which remains highly sought after synthetically.

274 ical for NAADP action and is likely the long sought after target channel for NAADP.

275 channel (TPC) family in mammals are the long sought after target channels for NAADP.

276 example, recent work suggests that the long-sought-after target of the analgesic acetaminophen is a

277 uishing features and probable locations of a sought-after target.

278 Chiral mono-ols are among the most sought after targets in asymmetric synthesis, and theref

279 rs of muscle health, they have become highly sought-after targets of physiological and pharmacologica

280 Eliminating leukemic stem cells (LSC) is a sought after therapeutic paradigm for the treatment of a

281 enotypic observations that are closer to the sought-after therapeutic effects using tools like artifi

282 s the receptor for nitric oxide and a highly sought-after therapeutic target for the management of ca

283 targeting therapy represents one of the most sought-after therapies for glioblastoma (GBM).

284 anced temporal and subcellular precision are sought after to both delineate physiological functions a

285 re effective anticonvulsants are continually sought after to combat this illness.

286 nst highly variable viral pathogens are much sought after to treat or protect against global circulat

287 acilitate basophil research and constitute a sought-after tool for diagnostic and drug testing purpos

288 ive precipitation of uranium may provide the sought-after tool to probe for biotic processes.

289 a quantum chain reaction that triggered the sought-after topochemical [2pai+2pai] photodimerization

290 ation remains among the most challenging and sought-after transformations in organic synthesis.

291 nversion of alkene stereochemistry are rare, sought-after transformations in the field of modern orga

292 l strategy for synthetic control over highly sought-after transition metal {M(4)O(4)} cubanes.

293 ndicates that it is a candidate for the long sought-after tubulin tyrosine carboxypeptidase important

294 this system will be able to detect the long sought after vacuum friction(7-10) near a surface under

295 can also act as a double-edged sword, as the sought-after variability can make it difficult to design

296 of the RTN are good candidates for the long sought-after VMS chemoreceptors.

297 Because nonopioid analgesics are much sought after, we computationally docked more than 301 mi

298 non-invasive integration, has been a highly sought after yet elusive goal.

299 -cis-glycopyranosidic linkage remains a long sought after yet unmet goal in carbohydrate chemistry.

300 ted drinks elicit a sensation that is highly sought after, yet the underlying neural mechanisms are i