ライフサイエンスコーパス: sparsely

1 ghness formation have only been investigated sparsely.

2 his approach are presented for two proteins, sparsely (13)C/uniformly (15)N-enriched CAP-Gly domain o

3 Conclusion: Adopting SIPs for sparsely acquired projections considerably recovers imag

4 Sparsely activated sets of neurons, coined "neuronal ens

5 We found that microstimulation sparsely activates neurons around the electrode, sometim

6 Under anesthesia, GCs were sparsely active and strongly and synchronously coupled t

7 l sensory pathways, input stimuli project to sparsely active downstream populations that have more ne

8 terns by mapping them onto larger numbers of sparsely active neurons.

9 in the primary somatosensory cortex (S1) are sparsely active, spontaneously and during sensory stimul

10 s 4-6, but not in layers 2/3, which remained sparsely active.

11 Some sexuality issues have been only sparsely addressed, such as gender-related differences,

12 (420), which is distributed sporadically and sparsely among prokaryotes.

13 ic/tyraminergic neurons contact Kenyon cells sparsely and are restricted mainly to the calyx, the alp

14 most ganglion cells in the salamander fired sparsely and idiosyncratically, so that their neural ima

15 oscillator in which individual neurons fire sparsely and stochastically.

16 Interestingly, hypoxia was detectable only sparsely and without spatial association with HIF-1alpha

17 Large clinical datasets are subject to sparsely and/or inconsistently populated fields.

18 We applied CrY2H-seq to investigate sparsely annotated Arabidopsis thaliana transcription fa

19 properly address this 'overfitting' issue of sparsely annotated functions, or do so in a manner scala

20 function prediction algorithms in predicting sparsely annotated functions, without sacrificing the pe

21 els to alleviate the overfitting problem for sparsely annotated functions.

22 However, the rabbit genome is still sparsely annotated, thus prohibiting extensive functiona

23 Ns densely innervate the glomerular core and sparsely arborize in the outer glomerular rind, overlapp

24 This problem has been studied only sparsely, as most of the existing work is limited to the

25 PSC clusters nucleosomes on sparsely assembled templates, suggesting it interacts pr

26 HVC, in which projection neurons (PNs) burst sparsely at stereotyped times in the song.

27 he exploration of regulatory networks in the sparsely available mammalian embryo.

28 All three subtypes formed sparsely branched and radiating dendrites, some longer t

29 Their large, sparsely branched arbors (mean diameter 275 microm) mono

30 showed that ICL-expressing neurons have more sparsely branched dendritic arbors, which expand over la

31 epression of VAC1, VAM2 and VAM3 resulted in sparsely branched hyphae, with large vacuoles and enlarg

32 eems to be greater in species with thick and sparsely branched roots than in species with thin and de

33 and generally multipolar and had extensive, sparsely branching central processes (presumptive dendri

34 Layer III neurons were only sparsely bursting (SB) and had no DAPs.

35 l neurons and distinguished two populations: sparsely bursting (~80%) and dominantly bursting neurons

36 Additionally, bursts fired by sparsely bursting cells encoded spatial information bett

37 Specifically, sparsely bursting cells have lower firing rates and carr

38 d to functional differences: the activity of sparsely bursting cells showed a stronger spatial modula

39 In most sparsely bursting cells, bursts defined sharper firing f

40 all cells classified as boundary cells were sparsely bursting cells.

41 insulin and glucagon genes are occupied only sparsely by H3K4me2 and H3K4me3.

42 dergic primary afferent nociceptors and more sparsely by low-threshold myelinated afferents.

43 cell types, their biological significance is sparsely characterized.

44 en pigmented (completely) and non pigmented (sparsely) colored rice cultivars followed by assessment

45 mutations deposited fibrillin-1 microfibrils sparsely compared with unaffected control cells.

46 The projection was sparsely connected and preferentially targeted a subset

47 ly meaningful modules within which nodes are sparsely connected but have similar interaction patterns

48 types of modules, within which proteins are sparsely connected but with significantly enriched biolo

49 dy analytically and numerically a network of sparsely connected excitatory and inhibitory integrate-a

50 In a sparsely connected model of MCs and GCs, we found first

51 Despite the potential for modularity between sparsely connected network motifs, Escherichia coli (E.

52 Thus, in a sparsely connected network, gap junctions between a smal

53 pped single-cell transcriptome data revealed sparsely connected networks linking specific neuronal su

54 h highly inter-connected central regions and sparsely connected peripheral regions.

55 entally study scrambling with as many as 100 sparsely connected quantum degrees of freedom.

56 igate temporally asymmetric Hebbian rules in sparsely connected recurrent rate networks and develop a

57 ferentially located in the central SCN, with sparsely connected shells surrounding these cores.

58 n subregions of M1 finger-related sites were sparsely connected with intermediate zone interneurons a

59 ated by excitatory neurons and synapses, are sparsely connected, and function with stereotypically di

60 thought to depend on coordinated activity in sparsely connected, complex networks organized over many

61 confirming a previous result, and that such sparsely connected, modular networks have higher overall

62 erial viruses, the archaeal virus network is sparsely connected.

63 inuously-varying weighted networks formed by sparsely-connected dynamical systems.

64 Striatal projection neurons form a sparsely-connected inhibitory network, and this arrangem

65 while avoiding cholinergic interneurons and sparsely contacting LTS interneurons, thus supporting in

66 ncluded in the models such that uncoupled or sparsely coupled cells show realistic interspike interva

67 Each long fragment of DNA is only sparsely covered by reads, no information about the orde

68 These plains are sparsely cratered, postdate the formation of the basin,

69 nguish between chromatin with heavily versus sparsely crosslinkable structures.

70 he spontaneously beating embryonic heart and sparsely cultured cardiomyocytes, including cells derive

71 Sparsely cultured E4 cardiomyocytes on collagen-coated g

72 ents with atopic dermatitis, yet it has been sparsely described in the literature.

73 ring childhood and adolescence has been only sparsely described.

74 ately labile, as well as heterogeneously and sparsely displayed.

75 genome level, H3K27me2 enrichment sites were sparsely distributed across chromosomes, within an avera

76 hat in the avian brain, where information is sparsely distributed across individual neurons, but rece

77 form cortex, whose responses to odorants are sparsely distributed across the cortex.

78 -S transgenic mice expressing GFP in neurons sparsely distributed across the superficial layers of th

79 ectively analyze metabolites and lipids from sparsely distributed algal cells and the lamellipodia of

80 yrus, interneurons positive for GABA/GAD are sparsely distributed along the edge of the hilus, in a d

81 The first, which we name Anbu, is sparsely distributed among cyanobacteria and proteobacte

82 However, the resulted information is sparsely distributed and no systematical summarization h

83 mbinase in FSIs allowed us to identify these sparsely distributed cells in the NAc.

84 into an internal division displaying larger, sparsely distributed cells, and an external division dis

85 In normal corneas, DCs were sparsely distributed centrally and were denser in the pe

86 nse islands, whereas methylation of the more sparsely distributed CpGs in the remainder of the genome

87 es beyond that possible with randomly and/or sparsely distributed enzymes, thereby matching supply wi

88 l Hodgkin lymphoma (cHL) is characterized by sparsely distributed Hodgkin and Reed-Sternberg (HRS) ce

89 selectively imaging cerebellar interneurons sparsely distributed in 3D space and by simultaneously r

90 Tendon cells are heterogenous and sparsely distributed in a dense collagen matrix; limitin

91 the initial segment, although UNC-16 is also sparsely distributed in distal regions of axons, includi

92 redominantly located in AVP neurons, however sparsely distributed in OC neurons of the PVN.

93 guished set of interacting networks that are sparsely distributed in the domain interface.

94 epithelial surface, as well as Psychromonas sparsely distributed internally.

95 Memory is thought to be encoded by sparsely distributed neuronal ensembles in memory-relate

96 effect will be accompanied by activation of sparsely distributed neurons (neuronal ensembles) throug

97 d by alterations within specific patterns of sparsely distributed neurons called neuronal ensembles t

98 mbrane and mimic the contractile activity of sparsely distributed NMIIA filaments.

99 ggest that these associations are encoded in sparsely distributed nucleus accumbens neurons that are

100 Levy flights were present when searching for sparsely distributed or potentially difficult-to-detect

101 Associative learning requires alterations in sparsely distributed populations of strongly activated n

102 bles in the NAc shell.SIGNIFICANCE STATEMENT Sparsely distributed sets of neurons called "neuronal en

103 cocaine activates only a small proportion of sparsely distributed striatal neurons.

104 nstructs to knock down MeCP2 expression in a sparsely distributed subset of layer (L) 2/3 pyramidal n

105 kine producers or weak consumption (e.g., by sparsely distributed target cells).

106 ng theory predicts that in environments with sparsely distributed target resources, where forager kno

107 ee-dimensional environments for randomly and sparsely distributed targets or when searching for targe

108 oendocrine (NE) cells are neurosensory cells sparsely distributed throughout the bronchial epithelium

109 copy and discover a low-energy singlet state sparsely distributed throughout the microcrystals, with

110 Fast-spiking interneurons (FSIs) are sparsely distributed throughout the NAc, forming local f

111 Because these are too sparsely distributed to permit complete retinal tiling,

112 ext-induced relapse to heroin, we identified sparsely distributed ventral medial prefrontal cortex (m

113 Some models demonstrate that when prey is sparsely distributed, an optimal search pattern is a spe

114 These 'microseizures' were sparsely distributed, more frequent in brain regions tha

115 re the representation of ITDs is known to be sparsely distributed, we performed the same analysis on

116 quantitative analysis of molecularly diverse sparsely-distributed features may benefit from 3D-recons

117 ranks at our educational institutions remain sparsely diverse.

118 ture history of the first millennium C.E. is sparsely documented, especially in the Arctic.

119 ed a repertoire of mechanisms until now only sparsely documented, namely longer intergenic regions, p

120 during, and after a social movement remains sparsely documented.

121 eurons both in vivo and in vitro do not fire sparsely during gamma, but rather on average every other

122 Green (MG) and can be used to label proteins sparsely, enabling single-protein detection in live bact

123 euron inhibition and allows input data to be sparsely encoded using neuron activities and stored dict

124 ield coupling in these systems has only been sparsely explored.

125 nnatural nucleotide surrogates has been only sparsely explored.

126 hip to patterns of brain development remains sparsely explored.

127 When an IgG1 anti-fHbp MAb binds to sparsely exposed fHbp on the bacterial surface, there ap

128 PLAG1 was sparsely expressed in germ cells and in Sertoli cells.

129 TRIC-B, in contrast, is sparsely expressed in most cells and, although lone TRIC

130 However, these receptors are only sparsely expressed in the prefrontal cortex, and how the

131 monly expressed in most eukaryotic cells, is sparsely expressed in the vomeronasal sensory neurons (V

132 atibilities alone and even when antigens are sparsely expressed on cardiac tissue.

133 sociated carbohydrate antigen, which is only sparsely expressed on healthy tissue.

134 d, Confocal images of sparsely expressed paQuasAr3 in brain slices.

135 mal subiculum are more similar to canonical, sparsely firing hippocampal place cells, whereas neurons

136 neurons may be particularly consequential in sparsely firing neural populations such as those found i

137 Despite the computational advantages to sparsely firing populations, experimental data defining

138 rk showing that single HVC(RA) neurons burst sparsely for a brief period of time during the productio

139 For instance, densely and sparsely grafted nanoparticles show distinct dispersion

140 These findings reveal a sparsely implemented memory retrieval mechanism in the h

141 ostly through small terminals in area 36 and sparsely in areas 28 and 35.

142 bits a fast plasma clearance in mice, occurs sparsely in human plasma (at one fortieth of the FH conc

143 GAT immunofluorescent puncta were first seen sparsely in NL at E9.

144 in all subpallial nuclei and in the pallium: sparsely in the medial pallial division (Dm); heavily in

145 Sox10(+) adult stem cells were found sparsely in the stroma of subcutaneous loose connective

146 The HIV-1 envelope glycoprotein (Env) is sparsely incorporated onto assembling virus particles on

147 We found that neurons and astrocytes were sparsely infected, but choroid plexus epithelial cells u

148 Sparsely infiltrated tumours exhibited a waning of neoan

149 Of three additional types of FTNs that were sparsely innervated by Purkinje cells, glutamatergic and

150 neous, whereas the intrinsic excitability of sparsely innervated FTNs varied widely.

151 tive examination of magmatic systems beneath sparsely instrumented volcanoes globally.

152 nstrated that individual pyramidal cells are sparsely interconnected by thousands of excitatory synap

153 re and a periphery are groups of densely and sparsely interconnected nodes, respectively.

154 ium consists of stratified epithelial cells, sparsely interspersed with dendritic cells (DCs) and a d

155 dependent systems-level neurobiology remains sparsely investigated in humans.

156 /D)(N/D)XX(S/T)S motif is an established but sparsely investigated motif for Ca(2+) binding.

157 Examples of higher homologues, which are sparsely investigated, will also be discussed.

158 eir long-term predictive value has only been sparsely investigated.

159 ased because other sensory systems have been sparsely investigated.

160 (223)Ra was significantly more potent than sparsely ionizing irradiation, with a median relative bi

161 ly greater carcinogenic effect compared with sparsely ionizing radiation that is prevalent on earth.

162 he effects of densely-ionizing deuterons and sparsely-ionizing X-rays on two microscopic fungi capabl

163 ts arise in a different manner than the more sparsely jointed long bones, and their identity is regul

164 iversification of wings in basal insects are sparsely known compared with more derived holometabolous

165 able, and scalable mouse genetic solution to sparsely label and illuminate the morphology of genetica

166 We used transgenic mice to sparsely label neuronal progenitors and observed that cl

167 We used transgenic and viral methods to sparsely label RGCs and characterized both dendritic and

168 rized fluorescence intensity fluctuations of sparsely labeled actin molecules.

169 We then tracked the orientation of sparsely labeled F-actin network at the leading edge of

170 n microscopy to image synaptic structures of sparsely labeled layer 2/3 neurons in the binocular zone

171 tition, we generated a transgenic mouse with sparsely labeled oligodendrocytes and establish that ind

172 icle detection models to be trained with few sparsely labeled particles and no labeled negatives.

173 s-peaks in (15)N-(1)H correlation spectra of sparsely labeled proteins is presented.

174 ocol for the assignment of NMR resonances of sparsely labeled proteins, namely, the ones labeled with

175 video rates, provided that the samples were sparsely labeled to limit overlap in their axially proje

176 By tracking sparsely-labeled cells, we also quantify cell influx int

177 nhibitory chemical synapse formation between sparsely labelled interneurons in clusters and the same

178 Protein binding to DNA molecules sparsely labelled with Cy3 results in an increase in flu

179 CNVs tend to be short and more sparsely located in the genome compared with CNAs.

180 rily located in the supragranular layers and sparsely located in the infragranular layers, whereas th

181 from the HapMap project, Admixture estimates sparsely mixed individuals better than Least-squares.

182 sequencing" (M2-seq) that takes advantage of sparsely mutated nucleotides to induce structural pertur

183 on responses, such as plant traits, are also sparsely observed in the tropics, with the most diverse

184 Solid-state NMR shows that Asp is sparsely occluded within vaterite and calcite.

185 nd predict that the response elements may be sparsely occupied on average.

186 In this technique, live cells are cultured sparsely on a thin scintillator plate and incubated with

187 er inhibitory interneurons and acetylcholine sparsely onto layer 1 interneurons and other VIP(+)/ChAT

188 agenesis of Ig genes, requiring it to act on sparsely or densely spaced uracil bases located in a var

189 These molecular metals have sparsely organized electronic states with distinctive vi

190 he track, with the remainder spread out more sparsely over the outer track region.

191 the PF-CwC synapses were the largest and had sparsely packed IMPs.

192 ence of infection thread-like structures and sparsely-packed plant cells in nodules suggest that bact

193 ction fluorescence microscopy, and PAGFP was sparsely photoactivated such that polarized fluorescence

194 ular layers and small number of viruses that sparsely populate the transducer surface.

195 airs (bps) exist in dynamic equilibrium with sparsely populated ( approximately 0.02-0.4%) and short-

196 tion measurements, however, demonstrate that sparsely populated (<1%), transient states involving non

197 revealed slow exchange dynamics involving a sparsely populated (p ~ 10%) and shortly lived (tau ~ 10

198 MR analysis of the kinetics and structure of sparsely populated [Formula: see text] oligomeric states

199 barrier densities occur in the most remote, sparsely populated alpine areas.

200 nostic and treatment services (especially in sparsely populated and rural areas), legal restrictions

201 ible to provide atomic-level descriptions of sparsely populated and transiently formed alternative co

202 ground state interconverts with a series of sparsely populated and transiently formed conformers, so

203 ation of NMR methods to detect four distinct sparsely populated and transiently formed thermally acce

204 ids undergo structural transitions to access sparsely populated and transiently lived conformational

205 ords with meanings that fell into densely or sparsely populated areas of semantic memory in two separ

206 nant in only 0.7 million km(2), primarily in sparsely populated areas of the mountainous western Unit

207 activation responsive RNA (TAR) by selecting sparsely populated but pre-existing conformations.

208 D. 1492) Amazonia was largely "pristine" and sparsely populated by slash-and-burn agriculturists, or

209 lly explored are only transiently formed and sparsely populated challenge current biophysical approac

210 main that proceeds via a transiently formed, sparsely populated compact on-pathway folding intermedia

211 le, which folds via a transiently formed and sparsely populated compact on-pathway intermediate, I.

212 ely proceeds via conformational selection of sparsely populated configurations of the N-terminal doma

213 Transient intermediates that are sparsely populated during protein folding have been iden

214 he transitions from the ground state to this sparsely populated excited state of L99A as observed thr

215 Graphene with sparsely populated H is difficult to dissociate due to i

216 compared to Abeta40 be rationalized from the sparsely populated high free energy states of the monome

217 ow them to sample structural states that are sparsely populated in the absence of a substrate or bind

218 Binding involves a sparsely populated intermediate that experiences hindere

219 ot" surfaces confers TAPBPR recognition of a sparsely populated MHC-I state attained through a global

220 cell density by redistributing themselves to sparsely populated MHPs.

221 ns facilitates the formation of a transient, sparsely populated productive complex between protease a

222 theory is determined by the dynamics in the sparsely populated region of the barrier top, its proper

223 released through a previously characterized, sparsely populated room-temperature excited state of the

224 ate interconverts with a transiently formed, sparsely populated second state with a lifetime of 250 m

225 an experimentally well characterized excited sparsely populated state as well as a ground state.

226 protofibril surface comprise an ensemble of sparsely populated states where each residue is either t

227 , a highly sensitive technique for detecting sparsely populated states.

228 states (excited states), which often are too sparsely populated to allow spectroscopic investigation.

229 ient compact states of free CaM that are too sparsely populated to observe by traditional NMR methods

230 -defined peak clusters separated by empty or sparsely populated trough regions.

231 By immune-targeting sparsely populated TTR misfolding intermediates (i.e. mo

232 dence, that the subplate itself is only very sparsely populated with GABAergic neurons at postnatal d

233 tween flexible (highly populated) and bound (sparsely populated) states.

234 copy facilitate atomic resolution studies of sparsely populated, transiently formed biomolecular conf

235 ET value between those of open and closed is sparsely populated.

236 ance within geographic circumstances (eg, in sparsely-populated regions vs dense urban areas).

237 ised by a range of mutations and resembles a sparsely-populated state in equilibrium with active HDAC

238 he context of the specific Oct1-DNA complex, sparsely-populated, spectroscopically "invisible" states

239 els; versican levels were relatively high in sparsely Qdot-labeled regions and low in densely labeled

240 ico-thalamic and thalamocortical neurons are sparsely recruited to successive seizures and consecutiv

241 contrast to the view that dendrites are only sparsely recruited under highly specific conditions in v

242 urgeries, and their subsequent outcomes, are sparsely reported from hotspots.

243 Health, social, and legal outcomes were sparsely reported, and few showed improvements.

244 -quality monolayer or few-layer antimonenes, sparsely reported, has greatly hindered the development

245 ety outcomes, including minor bleeding, were sparsely reported.

246 Treatment harms were poorly studied and sparsely reported.

247 Sensory stimuli are sparsely represented by approximately 2000 Kenyon cells,

248 ible, indicating that these regions are only sparsely represented in the circuit.

249 perimental structure determination, they are sparsely represented in the protein structure databank.

250 to a reduced space where the dynamics may be sparsely represented.

251 e describe a processing method for a pair of sparsely sampled 4D NOESY spectra, a methyl-methyl and a

252 re poorly suited to spatially and temporally sparsely sampled data, and permit only limited systemati

253 This suggests that fluctuations in the sparsely sampled experimental time series may be caused

254 , ProteoModlR enables functional analysis of sparsely sampled quantitative mass spectrometry experime

255 et performed significantly better when using sparsely sampled sinograms than conventional networks op

256 s and demonstrate that human bZIPs have only sparsely sampled the possible interaction space accessib

257 -related variation in the data for short and sparsely sampled time-series is described.

258 mes over the past two decades in the form of sparsely sampled, slowly fading emission from distant ga

259 al properties of connected pairs of neurons, sparsely sampling pairs from many specimens.

260 The AP morphologies of sparsely seeded cells (n = 32) displayed a significantly

261 (confluent monolayer) and 15,000 cells/well (sparsely-seeded) using a noninvasive optical method.

262 d pools, each of which contains thousands of sparsely sequenced long fragments ranging from 5 kilobas

263 Sparsely spaced (less than 7 branches cm(-1)), long late

264 ed in the stratum oriens or pyramidale, have sparsely spiny dendrites, and do not typically express s

265 trong after-hyperpolarizations and smooth or sparsely spiny dendritic morphologies resembling endogen

266 varied, and pleomorphic spines were found in sparsely spiny or densely spiny cells (1.5-5.2 spines/de

267 Migraine aura is sparsely studied due to the highly challenging task of c

268 f biologically active compounds but has been sparsely studied with respect to folding propensity.

269 ariation in injury risk and outcomes is more sparsely studied, but genetic testing for injury suscept

270 mended limits, on VF classification has been sparsely studied.

271 UC4 promotes metastasis of PC cells has been sparsely studied.

272 tcomes in type 1 diabetes mellitus have been sparsely studied.

273 ic media) has been exploited in syntheses of sparsely substituted analogues of chlorophyll b.

274 Prior studies of sparsely substituted synthetic chlorins to probe the eff

275 l routing in neural circuits, which exploits sparsely synchronized network oscillations and temporal

276 surements on artificial membranes, so-called sparsely tethered bilayer lipid membranes, reveal the st

277 on of GCase and alpha-syn.GCase complex on a sparsely-tethered lipid bilayer, revealing the orientati

278 schedule options where CT is performed more sparsely than in the NCCN guidelines during adjuvant ima

279 ches of pyramidal cells are distributed more sparsely than those of Purkinje cells.

280 At S-phase onset, origins fire randomly and sparsely throughout the chromosomes.

281 CM neurons respond sparsely to conspecific song and are tolerant of product

282 ns projecting from HVC to RA (HVC(RA) ) fire sparsely to drive RA activity during song production.

283 cells, a population of neurons that responds sparsely to odors, carries sensory information to and in

284 to the amygdala and entorhinal cortex (ERC), sparsely to prefrontal and cingulate cortices, and rarel

285 al differences in processing nociception, we sparsely traced non-peptidergic nociceptors across the b

286 maging, we found that EGCs were instead more sparsely tuned than MCs.

287 Systemic adjuvant treatment was sparsely used (8%).

288 Moench) has been sparsely used as human food due to certain anti-nutritio

289 aromatic bases, yet these processes are only sparsely used due to the perception of poor or unreliabl

290 microtubules, this class of assembly is only sparsely used in synthetic or colloidal analogues.

291 Many species that run or leap across sparsely vegetated habitats, including horses and deer,

292 In sparsely vegetated lands, the soil surface can be coloni

293 captures an earthquake surface rupture in a sparsely vegetated region with pre-earthquake lower-reso

294 ubs in the Low Arctic, but the more extreme, sparsely vegetated, cold and dry High Arctic is generall

295 fected mitochondrial morphology, RRECs grown sparsely were left untreated or treated with beta-glycer

296 etwork, in which flickers occur randomly and sparsely when a small number of mitochondria are in the

297 Before refinement, the CST terminated sparsely where calbindin interneurons were located and s

298 niques, showed that granule cells fired very sparsely, whereas mossy cells in the hilus fired promisc

299 nsely connected among each other but connect sparsely with others.

300 ted signaling events when they are scattered sparsely within the extracellular matrix (ECM) of the pa