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1 repeated for NCD mortality and did not vary spatiotemporally.
2 in shaping the development of the community spatiotemporally.
3 nt and physiology, although how motile cells spatiotemporally activate signaling events remains large
4 lopments, along with approaches to designing spatiotemporally actuated organelles based on multivalen
5 AutoPilot framework, an automated method for spatiotemporally adaptive imaging that integrates (i) a
6 ent a large-scale phylogenomic analysis of a spatiotemporally and clinically diverse set of 907 E. co
10 ing means to direct and confine drug release spatiotemporally at the site of interest with high speci
11 development is complex and highly regulated spatiotemporally by multipotent cardiac stem/progenitor
13 ontaneous motion, leading to actively driven spatiotemporally chaotic states in 2 and 3 dimensions an
14 insight into this phenomenon and demonstrate spatiotemporally coherent, cognitive representations tha
17 iting, thereby enabling the investigation of spatiotemporally complex physiological events by obtaini
18 hemical (acetylcholine) activation triggered spatiotemporally complex, propagating inositol trisphosp
19 tegrate cross-modal stimuli, but exposure to spatiotemporally concordant cross-modal stimuli was high
20 mance of animals in localizing and detecting spatiotemporally concordant visual and auditory stimuli
21 ocess that allows the brain to bind together spatiotemporally congruent inputs from different sensory
24 sexpression experiments in frog embryos, for spatiotemporally context-dependent activity of Ptf1a as
26 malian cells and discuss the mechanisms that spatiotemporally control PI conversion in endocytosis an
29 nto RNP granules, such as transcription, can spatiotemporally control the organization and dynamics o
30 and Cdkn2a(Flox)) and regulatory alleles to spatiotemporally control the perturbation of genes of in
31 Zn-directed RIDC3 assemblies can be used to spatiotemporally control the templated growth of small P
32 The ability to regulate gene activity in a spatiotemporally controllable manner is vital for biolog
33 lasticity of tumor cell migration and EMT is spatiotemporally controlled and connected upon challenge
34 rovide a basis for the future development of spatiotemporally controlled antinociceptive and antiinfl
35 s that influence the immune system should be spatiotemporally controlled as well, in order to maximiz
36 ndocytic trafficking-mediated mechanisms for spatiotemporally controlled axonal responses and uncover
39 can generate vapor microbubbles that can be spatiotemporally controlled by pulsed laser irradiation.
42 one-homing polymeric nanoparticles (NPs) for spatiotemporally controlled delivery of therapeutics to
45 hogenesis in vivo occurs through a series of spatiotemporally controlled events under the control of
46 elopment, such as cell specification and the spatiotemporally controlled formation of a three-dimensi
47 her expansion of the CRISPR/Cas9 system as a spatiotemporally controlled gene regulatory system, seve
48 cle Myosin II, but how this motor protein is spatiotemporally controlled is incompletely understood.
49 re the exact titration of RNA molecules in a spatiotemporally controlled manner, leading to developme
52 ork utilizes polymeric scaffold systems with spatiotemporally controlled morphogen cues to develop pr
53 of the data presented here, we propose that spatiotemporally controlled Myosin flows in conjunction
54 y pancreatin, providing the possibility of a spatiotemporally controlled release and protection of bo
55 light (red and NIR) has great potential for spatiotemporally controlled release of therapeutic agent
57 ur custom microfluidic control system allows spatiotemporally controlled stimulation with extracellul
58 tweezing cytometry (TB-ATC), for generating spatiotemporally controlled subcellular mechanical force
59 ons offers the promise of enabling on-demand spatiotemporally controlled therapeutic interventions.
61 al interactions can be probed in 2D or 3D by spatiotemporally controlling the gel microenvironment, w
62 n example of how differential receptor usage spatiotemporally controls and diversifies the effects of
63 date how localized Plexin-B1 stimulation may spatiotemporally coordinate its downstream targets in gu
66 HGEF7 and rhotekin, one Rho effector and the spatiotemporally coordinated activation of Rho GTPases (
67 tion to long-term nutrient starvation can be spatiotemporally coordinated and can occur independently
74 ngs indicate that KWL proteins are part of a spatiotemporally coordinated, plant-wide defense respons
75 PH) gene whose activity is indispensable for spatiotemporally correct expression of CYTOKININ INDEPEN
76 mechanism that increases RGC sensitivity to spatiotemporally correlated input, such as that produced
77 py allows the extraction of multidimensional spatiotemporally correlated structural information of di
78 , caused compromised astrocyte morphogenesis spatiotemporally correlated to synaptic overgrowth, with
79 ation and dynamics of synaptic podosomes are spatiotemporally correlated with changes in AChR aggrega
80 all puncta adjacent to AChR clusters and was spatiotemporally correlated with the formation and maint
81 the barrier zones at speeds ~10 to 600 m/h, spatiotemporally correlated with the observed migration
82 multaneous hemodynamic imaging confirms that spatiotemporally coupled functional hyperemia is not pre
87 -protein technology is devised to tailor the spatiotemporally defined delivery of therapeutic protein
89 powerful and precise approach for revealing spatiotemporally defined physiological functions of PA.
92 aging provide order-of-magnitude speedups in spatiotemporally demixing calcium video data into estima
93 This represents improved detection during spatiotemporally dense spiking, and yielded sharper sens
94 urface channel geometry, mass flow rate, and spatiotemporally dependent pore-water pressure feedback
95 ve shown that this process relies on signals spatiotemporally deployed in the extra-embryonic tissues
96 the Soil and Water Assessment Tool to model spatiotemporally differentiated effects on maize yield,
99 V1 and V2 of behaving monkeys, we identified spatiotemporally dissociable processes for grouping cont
100 that the modular network in mouse V1 selects spatiotemporally distinct clusters of neurons within the
102 al induction is controlled by conserved, yet spatiotemporally distinct mechanisms that co-ordinate de
103 ia, and instead indicate the presence of two spatiotemporally distinct modes of cross-linking in S. a
104 that propofol-induced LOC is accompanied by spatiotemporally distinct oscillatory neuronal dynamics
105 that visual input from the two eyes provides spatiotemporally distinct signals to primary visual cort
106 that physiological doses of UVA generate two spatiotemporally distinct sources of ROS: one upstream o
107 that propofol-induced LOC is accompanied by spatiotemporally distinctive neuronal dynamics in this n
108 unclear how apical constriction is regulated spatiotemporally during tissue invagination and how this
110 o reveal that in the embryonic midbrain, the spatiotemporally dynamic Shh domain defines multiple pro
111 Collectively, these data underscore multiple spatiotemporally dynamic Wnt-secreting niches that regul
112 ynamic connectivity studies are presented as spatiotemporally dynamic, even though they fall into dif
113 t the concepts of spatially, temporally, and spatiotemporally dynamics and use this terminology to ca
114 in a highly autonomous manner, recapitulate spatiotemporally each of the main steps of retinal devel
115 icts that the Ca(2+) and NO levels alternate spatiotemporally, establishing complementary feedback lo
116 redator-prey diel comparisons, we considered spatiotemporally explicit predator access to several pre
117 nstrate the efficacy of this estimator using spatiotemporally explicit simulations and apply it to a
118 n North American fossil occurrences within a spatiotemporally explicit stratigraphic framework that a
119 articipate in directing the highly regulated spatiotemporally expressed genetic network during implan
120 ), the major effector of Hippo signaling, is spatiotemporally expressed in ovarian granulosa cells an
121 miRNAs, mmu-miR-101a and mmu-miR-199a*, are spatiotemporally expressed in the mouse uterus during im
122 variety of observational datasets to create spatiotemporally extensive datasets for land model verif
123 ons within the corneolimbal epithelium, then spatiotemporally fate-mapping cell behavior during heali
125 +)) cycling dynamics in cardiac myocytes are spatiotemporally generated by stochastic events arising
126 les can simultaneously exhibit transient and spatiotemporally heterogeneous behavior, there is an exi
127 here the incidence of Ebola virus disease is spatiotemporally heterogeneous, and is decreasing rapidl
128 icrofluidic diffusive mixers can be used for spatiotemporally high-throughput characterization of bac
131 lly new way to engineer molecular assemblies spatiotemporally in cellular microenvironment for inhibi
133 n biogeochemistry, and their abundances vary spatiotemporally in the global oceans, with upper estima
135 al cues received at the plasma membrane (PM) spatiotemporally integrate to the functional chromatin o
136 date how MAPK and PKA signaling cascades are spatiotemporally integrated in a single neuron to suppor
137 he oscillatory activity transitioned to more spatiotemporally irregular patterns, and synchronous net
138 agent that can be light activated to achieve spatiotemporally limited inhibition of Rho kinase activi
139 so describes TPLSM laser ablation, which can spatiotemporally manipulate specific cellular population
141 ance-dependent positive feedback loop, which spatiotemporally may act as a tension sensor at centrome
142 n with mechanistic implications as to how it spatiotemporally mediates integrin signaling and cell ad
144 show theoretically and experimentally that a spatiotemporally modulated device can be designed to hav
145 ual stimulus dome that allowed us to present spatiotemporally modulated UV and green luminance in any
146 al RNA editing and nucleic acid detection by spatiotemporally modulating endonuclease activities.
147 provides a direct and noninvasive method to spatiotemporally monitor biofilm accumulation in the sub
148 erase (luc) to competence-specific genes and spatiotemporally monitored the competence development in
151 e receptive fields of both T4 and T5 exhibit spatiotemporally offset light-preferring and dark-prefer
152 locus with the Legionella effector SidJ that spatiotemporally opposes the toxicity of these enzymes i
154 ESCRT-III assembly is highly dynamic and spatiotemporally ordered, but the underlying mechanisms
155 at slow brain rhythms predominantly indicate spatiotemporally organized activity in local nerve cell
157 Aggregate signals in cortex are known to be spatiotemporally organized as propagating waves across t
158 To investigate how chromatin architecture is spatiotemporally organized at a double-strand break (DSB
159 We show here that cortical spindles are spatiotemporally organized into circular wave-like patte
161 fundamental roles for Merlin/ERM proteins in spatiotemporally organizing the cell cortex and suggest
162 ne disulfide (GSSG) treatments induced rapid spatiotemporally overlapping cytosolic Ca(2+), H(+), and
165 only available light sources are employed to spatiotemporally pattern protein release from hydrogels
167 a lack of versatile devices that can deliver spatiotemporally patterned light while performing simult
168 Using optogenetic techniques, we delivered spatiotemporally patterned stimuli to neurons and confir
171 widespread recognition of the importance of spatiotemporally precise causal control over cellular si
172 of user-selected neurons to be targeted for spatiotemporally precise concurrent optogenetic activati
173 rs, technological limitations have prevented spatiotemporally precise control over intracellular sign
174 ancers, play a central role in orchestrating spatiotemporally precise gene-expression programs during
175 mally invasive delivery of gene vectors in a spatiotemporally precise manner, reducing intra-articula
177 switchable fluorescent protein that enables spatiotemporally precise marking, erasing, and remarking
178 t ultrasonic stimulation is an effective and spatiotemporally precise method to activate the retina.
179 tubule stabilisers thus enable non-invasive, spatiotemporally precise modulation of the microtubule c
180 developed a motor task for rats that trains spatiotemporally precise movement patterns without requi
181 cific optogenetic approach is a powerful and spatiotemporally precise neural inactivation tool with b
183 ich denotes the noninvasive, reversible, and spatiotemporally precise perturbation by light of living
184 s technology promises to enable evocation of spatiotemporally precise responses in targeted cells or
189 oding directions were acquired sequentially, spatiotemporally registered, and retrospectively selecte
190 oteins are unique transcription factors that spatiotemporally regulate gene expression by tethering t
191 viruses can form biomolecular condensates to spatiotemporally regulate N protein localization and fun
197 ously proposed, because its activity must be spatiotemporally regulated both preanaphase and postanap
199 complex developmental process that involves spatiotemporally regulated coordination between the germ
201 dynamics, we show that leader cells form by spatiotemporally regulated endoreplication, caused prima
204 onship between cofilin and myosin II that is spatiotemporally regulated in the growth cone via mechan
206 ow these many functions are carried out in a spatiotemporally regulated manner in a single cytoplasm
207 heparan sulfate proteoglycans expressed in a spatiotemporally regulated manner in many developing tis
208 cell types and growth factors that act in a spatiotemporally regulated manner, is triggered by a mec
210 planar polarity is rapidly established in a spatiotemporally regulated pattern that is dynamically r
211 l of material properties through independent spatiotemporally regulated photocleavage of crosslinks a
214 anized tissue structure is generated through spatiotemporally regulated responses to EGF receptor act
217 ed activity of these different components is spatiotemporally regulated to ensure efficient spindle a
218 ults suggest that CRL5 adaptor expression is spatiotemporally regulated to modulate Reelin signaling
221 hat the cofilin phosphatase chronophin (CIN) spatiotemporally regulates cofilin activity at the cell
222 advances describing how the actomyosin ring spatiotemporally regulates membrane traffic to promote s
224 assive membrane properties of cells that are spatiotemporally relevant to the pattern of retraction i
226 the mechanisms by which the invadopodia can spatiotemporally reorganize their architecture is not we
227 ore show that this probe can selectively and spatiotemporally report UCHL1 activity during the develo
228 Here, we developed a cell-type-specific, spatiotemporally resolved approach to profile cell-surfa
229 ured at stationary monitoring sites, and for spatiotemporally resolved estimates of PM2.5 and BC at t
231 is a novel, nondestructive tool that allows spatiotemporally resolved measurement of CaMKII activati
232 llular-resolution expression data produced a spatiotemporally resolved metazoan transcription factor
236 rameters) and can thus be exploited to offer spatiotemporally resolved prediction of UFPs on freeways
237 ) measurements have the potential to provide spatiotemporally resolved predictions of both long and s
238 c analysis of imaging data allowed accurate, spatiotemporally resolved quantification of two differen
239 BF) at the river Thur was studied using both spatiotemporally resolved sampling and single-well push-
242 whole-plant level, allowing for a systemic, spatiotemporally resolved understanding of metabolic pro
243 om-up (BU) approach has been used to develop spatiotemporally resolved, sectorally disaggregated foss
244 g of programed cells, including logic gates, spatiotemporally responsive patterning, and wearable dev
247 sophosphatidic acid (LPA) gradient induces a spatiotemporally restricted decrease in the mobility of
249 protrusion formation and migration and that spatiotemporally restricted ectopic activation is capabl
250 enhancers to mediate quantitative changes in spatiotemporally restricted expression patterns during a
252 d reversible, rapidly switchable patterns of spatiotemporally restricted GPCR activity in a single ce
254 from Rose, Jin, and Craig demonstrating that spatiotemporally restricted NMDA receptor excitation at
257 applied these spatially explicit models to a spatiotemporally robust dataset of sage-grouse nest loca
260 king advantage of the wireless, scalable and spatiotemporally selective capabilities that light allow
262 ons of the NAc during a behavioral task that spatiotemporally separated sequential goal-directed stim
263 thylated motifs were highly conserved across spatiotemporally separated Trichodesmium isolates, there
264 Conservation of these intergenic regions in spatiotemporally separated Trichodesmium populations sug
265 stimate motion by cross-correlating pairs of spatiotemporally separated visual signals, but recent ex
266 e lipids bind its C-terminal SH2 domain in a spatiotemporally specific manner and thereby exert exqui
267 l concentrations are tightly controlled in a spatiotemporally specific manner, the simultaneous quant
268 nd sex steroids shape brain development in a spatiotemporally specific manner, within neural systems
270 te their combinatorial activities with other spatiotemporally specific transcription factors (bHLH/NR
273 ensembles of CA3 pyramidal neurons produces spatiotemporally structured input patterns arriving onto
274 ther the production of twitches is random or spatiotemporally structured, or whether the patterning o
278 stress transmission along the actin bundle, spatiotemporally synchronizes actin disassembly and fibe
280 nclear how the activity of ACF7 is regulated spatiotemporally to achieve focal adhesion-specific guid
282 muli that selectively targeted four distinct spatiotemporally tuned channels with center frequencies
283 dependence in perception characterized by a spatiotemporally tuned, orientation-selective operator-w
284 ght-activated proton pump in mitochondria to spatiotemporally "turn off" mitochondrial function throu
287 equent in paroxysmal than persistent AF, are spatiotemporally unstable, are not the source of centrif
289 n adaptive bet-hedging strategy to cope with spatiotemporally variable environments, particularly flu
294 ing approach (Random Forest (RF)) to develop spatiotemporally varying NEE estimates using observation
295 and detection planes are common owing to the spatiotemporally varying optical properties of living sp
297 uman RP and the rd10 mouse model, coinciding spatiotemporally with photoreceptor degeneration, with i
300 rivatives of the three germ layers organized spatiotemporally, without additional extra-embryonic tis