ライフサイエンスコーパス: species difference

1 onal hPSC is due to cell state rather than a species difference.

2 MDA receptor subunits, suggesting a possible species difference.

3 pstream duplicated site, thus explaining the species difference.

4 te antitumor activity, displays a pronounced species difference.

5 Here we attribute the discrepancy to species differences.

6 rcolepsy, including therapeutic drug use and species differences.

7 dies to better establish the extent of these species differences.

8 ion as being strongly linked to the observed species differences.

9 ich morphological and genetic data concur on species differences.

10 ied before they become confounded with other species differences.

11 nd extinction may play a significant part in species differences.

12 ith both the phenotypic variability and with species differences.

13 selection and the pattern of individual and species differences.

14 response to hyperoxia are most likely due to species differences.

15 verged towards the same traits regardless of species differences.

16 ways translatable to humans because of major species differences.

17 the dominant paradigm of greater-than-chance species differences.

18 ort periods of supra-optimal heat, revealing species differences.

19 e highly dissimilar, and that there are also species differences.

20 understand the evolutionary forces acting on species differences.

21 ingle-base resolution there are considerable species differences.

22 processes and delay the acceptance of valid species differences.

23 t in onion species to reveal important inter-species differences.

24 n the in vivo brain and found no significant species' difference.

25 redictability in the genetic architecture of species differences across groups of related species.

26 Dramatic species differences also existed in CART peptide distrib

27 ion genes do not seem to have a role in this species difference although D. sechellia is sexually dim

28 monocytes; conserved neutrophil subsets; and species differences among macrophages.

29 Seasonal excretion of this protein, species difference and male-specific expression during t

30 se and human) suggest subtle but fundamental species differences and AD transgene effects.

31 These data reveal important species differences and elaborate cell type requirements

32 nal modifications, links to precursor genes, species differences and relationships with other molecul

33 However, due to potential species differences and the inability of models to fully

34 proteome, followed by normalization of inter-species differences, and Markov clustering.

35 Here, I argue that the origin of species differences, and of novel phenotypes in general,

36 he fraction of unbound chemical, f(U)); (iv) species differences; and (v) extrahepatic biotransformat

37 the size and distribution of QTL underlying species differences are complicated by differences in th

38 ess requires determining which processes and species differences are most important for coexistence w

39 scence confocal microscopy and find that the species differences are profound; the vast majority (>75

40 However, TRPA1 species differences are substantial and limit translatio

41 We suggest that these species differences arise from differences in rule encod

42 Interpretations of these evolutionary and species differences as continuities or discontinuities r

43 s tumor specificity is not attributable to a species difference between human tumor and mouse normal

44 transplantation, demonstrating a substantial species difference between mouse and man.

45 iation in the E3 loop is responsible for the species difference between rat and human BRS-3, and mult

46 l song patterns and may reflect an important species difference between zebra finches and Bengalese f

47 vel approach for the quantification of inter-species differences between mouse, rat and human.

48 Species differences between the RAS of rodents and human

49 cription, formalising and highlighting inter-species differences both in the kinetics and in the regu

50 ypotheses about species coexistence hinge on species differences, but quantifying trait differences a

51 Species differences can originate before reproductive is

52 This species difference contrasts with performance on a tempo

53 Species differences demonstrated the importance of testi

54 mouse islet GPCR atlas has demonstrated that species differences do exist in islet GPCR expression an

55 Such species differences do not appear to exist at the level

56 ween synaptic activity and spike firing, and species differences encourage caution when comparing BOL

57 First, species differences exist in the location of the motoneu

58 Thus, species differences exist in the neuronal organization o

59 sance variance in genetic diversity owing to species differences, for example, in mutation rates or h

60 es that there are actually rather widespread species differences, for example, in the transmission of

61 importance of distinguishing illusory cross-species differences from the true evolutionary differenc

62 nd C6-deficient rabbit blood could be due to species differences governing the susceptibility of plat

63 The reason for these dramatic species differences has remained unclear.

64 Our work thus provides strong evidence that species differences have a critical role in stabilizing

65 As between-species differences have been reported in the duration a

66 dicate that position 5.46 contributed to the species difference in 5-HT(2A) receptor potency observed

67 The results explain the marked species difference in antagonist sensitivity and identif

68 This may reflect a profound species difference in beta cell regeneration pathways in

69 es for FXR function but may also explain the species difference in bile acids/cholesterol metabolism.

70 dings provide a possible explanation for the species difference in disease phenotypes observed with H

71 least two or three genomic regions, and the species difference in interpulse interval may be oligoge

72 with LAIR-2 rarely occurs, implying that the species difference in LAIR-1 genetic pathways could not

73 Z genes showing the greatest species difference in M:F ratio were concentrated near t

74 In conclusion, this study unveils a species difference in nutrient regulation of the human a

75 These findings reveal an important species difference in OCN regulation, which may explain

76 , we address the possibility that this large species difference in onset latencies is caused experime

77 Underlying this species difference in susceptibility to apoptosis follow

78 d in the dog model indicates that there is a species difference in the amount of RPE65 required to dr

79 A species difference in the arrangement of AZM relative to

80 Thus, our data show an important species difference in the chemical distinction of inhibi

81 To examine further this apparent species difference in the cholinergic effectors for the

82 Thus, there is a marked species difference in the immunoreactivity of Kv3.1b in

83 IEG expression that we observed represents a species difference in the mechanisms of IEG transcriptio

84 The data also point to an intrinsic cross-species difference in the organization of 5' non-coding

85 These contrasting results suggest a species difference in the perceptionand use of features

86 ality with neural-tube defects, suggesting a species difference in the requirement for RAB23 during e

87 This species difference in the role of ATOH8 is explained in

88 However, there is a species difference in the timing of acquiring Nkx2.2 exp

89 dicates that residues 59 and 115 mediate the species difference in Wtx-1 affinity.

90 be translated to humans given the pronounced species differences in ABCG2/ABCB1 expression ratios at

91 ignals, a process widely assumed to generate species differences in adaptive radiation.

92 The developmental bases for species differences in adult phenotypes remain largely u

93 elate significantly with both individual and species differences in aggression, likely reflecting evo

94 s directed toward rationalizing the observed species differences in AhR sensitivity to TCDD and under

95 vivo work that demonstrated ligand-dependent species differences in AHR1 affinity.

96 Species differences in amplitude of these pH(i) changes

97 t influenza A virus polymerase activity, and species differences in ANP32A can restrict the host rang

98 upled receptors has been the exploitation of species differences in antagonist potencies.

99 Species differences in basal cocaine- and amphetamine-re

100 elopmental comparative approach, we assessed species differences in behavior, hypothalamic activity,

101 n inform our understanding of individual and species differences in behavioral mechanisms.

102 that evolutionary models explaining between-species differences in behaviour can be used to understa

103 in lotic food webs is relatively low, though species differences in bioaccumulation patterns are impo

104 We tested the hypothesis that species differences in body size and microhabitat use (a

105 ilure of the cerebrotype measure to identify species differences in brain architecture that are indep

106 ere, we test these assumptions and show that species differences in brain size build memory capacity

107 However, species differences in brain structure and connectivity

108 Hence, while confirming expected inter-species differences in calcium sensitivity due to large

109 Large species differences in CART mRNA distribution were appar

110 Here we report that there are significant species differences in CB2R mRNA splicing and expression

111 hether this functional variability is due to species differences in CCK receptor structure or to alte

112 o observed that there were significant intra-species differences in Cd tolerance of L. plantarum stra

113 These results indicate substantial species differences in CD33 expression patterns and liga

114 The biological basis for regional and inter-species differences in cerebral cortical morphology is p

115 at the connectivity itself could account for species differences in circuit responses to curare.

116 Recently, it was demonstrated that even species differences in complex social behavior may be at

117 whether microhabitat use was associated with species differences in CTmax and whether microhabitat wa

118 cesses other than Rleaf were responsible for species differences in CUE's temperature response.

119 ation of CYP2D6 substrates because of marked species differences in CYP2D isoforms.

120 To address the possibility of major species differences in DCN organization, we compared Nis

121 More broadly, it shows how species differences in dispersal and establishment may r

122 Pronounced species differences in distribution were few, although m

123 conformations of FtsZ were related to inter-species differences in domain orientation rather than tw

124 ar to internalization, there are agonist and species differences in down-regulation of kappa-opioid r

125 PE (CRPE) were measured to determine whether species differences in drug transport can be explained o

126 maintenance of reproductive isolation and to species differences in ecologically important traits.

127 phant tusks were scanned and we utilized the species differences in elemental composition to develop

128 Species differences in embryonic development and archite

129 rat ENaC current, indicating that there are species differences in ENaC regulation by protons.

130 a minority (0 to 25%) of between- and within-species differences in enzyme activity.

131 min from other species, and this may suggest species differences in epitope specificity for self prot

132 Species differences in female pheromone composition and

133 ing body of research addressing the topic of species differences in fish acoustic signals suggests th

134 Despite some inter-species differences in flipper stroke dynamics or freque

135 ifferences in research methodology and cross-species differences in functional neuroanatomy.

136 This resulted predominantly from species differences in gammaENaC.

137 d mouse have molecular correlates, including species differences in gene expression in subplate, alth

138 Our results highlight species differences in GPR15 regulation and suggest it a

139 dorsal LS is also associated with year-round species differences in grouping in estrildid finches, su

140 tic hydrocarbons, but the role of the AHR in species differences in HAH sensitivity is not well under

141 Our results inform the genetics of species differences in Helianthus and suggest an approac

142 rather than phenolic-based defence, explain species differences in herbivory, leaf lifespan and shad

143 This restriction has been associated with species differences in host factor ANP32A.

144 is a significant target of TCDD and support species differences in hs1,2 regulation.

145 (P > 0.05), results consistent with observed species differences in IC(5)(0) values obtained by aggre

146 us represent potential contributors to inter-species differences in immunity.

147 We herein describe sex and species differences in immunoreactivity for tyrosine hyd

148 Species differences in knob asymmetry and overall volume

149 Cross-species differences in leaf-wide growth determine the ou

150 transcription factor with significant inter-species differences in ligand-dependent activation.

151 We show that functional tradeoffs explain species differences in long-term population dynamics tha

152 nt ectopic recombination within the MSY, and species differences in mating behaviour.

153 ithin-population SGS reflected known between-species differences in mating systems.

154 Species differences in microhabitat use can expose anima

155 used these datasets to identify mouse-human species differences in microvessel-associated gene expre

156 Having the advantage of species differences in mouse x human hybrids, we are abl

157 s of cis- and trans-regulatory divergence to species differences in mRNA abundance and translation ef

158 nslation regulatory divergence often buffers species differences in mRNA abundance, such that ribosom

159 ruction behavior and bower form that reflect species differences in nature, and we gain new insights

160 -factor regulation might have contributed to species differences in nephron progenitor programs such

161 behavior of male mammals are attributable to species differences in neurochemistry, including differe

162 These species differences in neuropil distribution may offer i

163 These studies suggest that there are marked species differences in NHE3 expression in the distal nep

164 omparable to numbers of genes accounting for species differences in other studies.

165 ifferences also explained a larger number of species differences in overall expression level.

166 Species differences in perception have been linked to di

167 To examine the mechanism determining species differences in peroxisome proliferator response

168 1a genotypes explain both within and between species differences in personality traits of bonobos and

169 ies has been limited in murine models due to species differences in pharmacokinetics and biologic res

170 In this context, knowledge of inter-species differences in physiology is crucial for underst

171 the CRD in PI binding and reveal unexpected species differences in PI recognition that can be largel

172 mutants of the two species further show that species differences in pigment pattern reflect: (1) chan

173 This pattern is concordant with species differences in population density and social spa

174 nt beta3-adrenoceptor, yielding considerable species differences in potency.

175 s generally failed both to take into account species differences in prefrontal function that lead to

176 limited relevance for humans due to between-species differences in pregnancy physiology.

177 e arises as to whether there might be within-species differences in processing speed between photorec

178 These species differences in projection patterns provide furth

179 n to cause rodent hepatic tumors, the marked species differences in PXR/CAR structure, expression pat

180 ng in human cognitive development [1-4], but species differences in reading human social cues remain

181 In the novel object preference test, no species differences in recognition memory were detected,

182 ormance in both species, but there were also species differences in relative sensitivity to higher an

183 alization to scleral thickness abolished the species differences in scleral transport.

184 Tissue thickness accounts for the species differences in scleral transport.

185 and melanin content largely account for the species differences in SCRPE transport.

186 ss and melanin content significantly reduced species differences in SCRPE transport.

187 studies provide a molecular understanding of species differences in sensitivity to dioxin-like compou

188 These effects are driven by species differences in sensitivity to environmental cond

189 is essential to predicting and interpreting species differences in sensitivity to toxicity caused by

190 These results indicate that there are species differences in sensitivity to TRAIL, and that su

191 Although there were dramatic species differences in several morphometric measures, el

192 g the temporal delay to disease onset, broad species differences in severity, and diversity of skelet

193 rm our understanding of individual, sex, and species differences in social behavior later in life.

194 1a receptor is a gene known to be central to species differences in social behavior, including differ

195 eptor distribution and thereby contribute to species differences in social behavior.

196 provide a potential molecular mechanism for species differences in social organization.

197 animal societies and has been implicated in species differences in sociality, the environmental pred

198 To evaluate potential species differences in spatial memory and object recogni

199 These observations suggest that while species differences in spatial memory retention are pres

200 If species differences in spatial scale are taken into cons

201 en mouse and rabbit hearts, we found notable species differences in spatio-temporal repolarization dy

202 Studies in macaque and rat suggest species differences in steroid action.

203 temporal] for unresolved harmonics) and that species differences in stimulus resolvability need to be

204 rats and mice suggest an explanation for the species differences in susceptibility to C. neoformans b

205 Here we integrate species differences in susceptibility with multiple in-d

206 There are between-species differences in syrinx measurements, despite simi

207 (QP) theory may be able to account for these species differences in terms of orthogonal versus nonort

208 neuropeptide receptor expression may explain species differences in the ability to form pair bonds.

209 Marked species differences in the actions of UII question its i

210 and other primate species that could explain species differences in the capacity for relational reaso

211 These data suggest that species differences in the CCK(A) receptor of rats and m

212 nd physiology, we ask here if there are also species differences in the connectivity of the LM.

213 Our results illustrate how species differences in the control of ion-channel gene e

214 hical locations, there were geographical and species differences in the distribution of resistance de

215 There are major species differences in the effects of aging on aortic co

216 Indeed, we report here that there are strong species differences in the expression and regulation of

217 sal clades of placental mammals has produced species differences in the functional types of hemoglobi

218 Species differences in the location of the Ca2+-dependen

219 facilitating exchange, we reveal substantial species differences in the mechanism of VSG diversificat

220 puts to barrel cortex, with implications for species differences in the nature and plasticity of lemn

221 e found in the Hp of all four species and no species differences in the number of NPY cells was obser

222 2) binding among the four species, including species differences in the olfactory bulb, nucleus accum

223 ampus and that their phase may contribute to species differences in the optimal phase for learning.

224 se findings suggest that despite substantial species differences in the organization of hippocampal c

225 following each reversal and did not reflect species differences in the rate of initial discriminatio

226 ns to determine whether there were important species differences in the response to cocaine.

227 emporal dynamics of NO diffusion and suggest species differences in the role of NO in the mushroom bo

228 er or in mouse, and they highlight potential species differences in the role of SP within the SCN cir

229 Only modest species differences in the signaling profile of AM1710 w

230 These findings suggest that species differences in the splicing and expression of CB

231 The findings revealed no quantitative species differences in the three cortical areas examined

232 mouse and rat brain raise the possibility of species differences in the transport of IL-1 across the

233 We found robust species differences in the volume of this new area, meas

234 sed by mutant Pde6h/PDE6H suggest species-to-species differences in the vulnerability of biochemical

235 However, species differences in their gene structures mean that m

236 Inter-species differences in their toxicokinetics and toxicody

237 We conclude sympatric species differences in thermal physiology correspond to

238 Therefore, there may be species differences in these projections that are import

239 However, there are striking species differences in these properties.

240 Species differences in this spatial task appear quantita

241 acting transcription factors, is critical to species differences in tissue-specific TERT expression.

242 Our study highlights important species differences in Ucn 3 expression, which have impl

243 rie vole receptor gene may contribute to the species differences in vasopressin-receptor expression.

244 igenic variation in African trypanosomes and species differences in virulence and transmission, requi

245 interaction was investigated by using cross-species differences in VWF storage.

246 nd forest ecosystem functioning, with strong species differences in water and nutrient use.

247 There were also species differences in worker retinue attraction to thre

248 lid phylogeny offered no value to predicting species' differences in SINs through phylogenetic signal

249 to the core genome that is conserved between species, differences in gene content can be linked to th

250 Winter-specific species differences include a substantial increase of MT

251 enes, the CD33rSiglec genes showed extensive species differences, including expansions of gene subset

252 The molecular basis of this species difference is not known.

253 One factor that contributes to the species differences is the bZip protein CES-2.

254 Given such complexity and pronounced species differences, it is a considerable challenge to d

255 These species differences likely relate to flocking rather tha

256 Since species differences limit the utility of animal tissues

257 This finding is explained by cross-species differences mainly found within domain III (DIII

258 he fundamentals of the Mhc, and defining the species differences makes the model organisms more usefu

259 This species difference may be driven by the unique demands o

260 This species difference may hinder the dissection of aspects

261 We hypothesized that species differences might result from differences in pos

262 e.g., flat structure-activity relationships, species differences, "molecular switches"), have been id

263 tion, potentially accounting for some of the species differences observed in IVIG protection.

264 A gradient of bacterial species (difference of the sum of the relative abundance

265 ric Kir2.x complexes, determine regional and species differences of I(K1) in the heart.

266 Across-species differences of this interneuron are also observe

267 ecause divergent findings may reflect actual species differences or arise from discrepancies in techn

268 These discrepancies may reflect inter-species differences or complex interplay of FGF21 activi

269 mouse and human embryonic stem cells reflect species differences or diverse temporal origins.

270 Introgression can also erode species differences over time, but selection against int

271 duction could help address this challenge as species differences preclude extrapolation from animals.

272 esearch on speciation, leaving the origin of species differences relatively poorly understood.

273 mperature and pacing rate, and conclude that species differences require only changes in myosin affin

274 e classic neo-darwinian view postulates that species differences result from the accumulation of smal

275 We hypothesized that these species differences result in part from a weak or absent

276 s of killifish, rat, and human CYP1As showed species differences similar to those with TCB, but with

277 Thus, these species differences suggest that the human-specific shif

278 ges in puberty and typically more pronounced species differences than other body parts.

279 n this study, we take advantage of the large species difference that exists between human and rat CNT

280 in-like A1 subdomains in fVIII contain inter-species differences that are a result of selective press

281 rentiate complementarity into three types of species differences that may cause enhanced ecosystem fu

282 among some EN subtypes, but we note multiple species differences that should be carefully considered

283 However, because of the species differences, the findings in EEG should be confi

284 nvestigated at the human enzyme did not show species differences; they displayed high selectivity ver

285 he DM phenotype; because of insulin-receptor species differences, this effect is not seen in mouse mo

286 ategy to inhibit costimulation that exploits species differences using the model of porcine pancreati

287 This species difference was conferred by only one residue in

288 This species difference was due to the absence of delta-lyase

289 To explore the molecular basis for these species differences, we analyzed the function of the lig

290 mine how individual differences compare with species differences, we characterize variability in the

291 To understand the molecular basis of the species differences, we constructed two Flag-tagged chim

292 Depending on the binding mode, large species differences were found, e.g., 2-piperazinyl-AOPC

293 e similar across all grazing treatments, and species differences were maintained in the common-garden

294 Site-by-species differences were not statistically significant.

295 Unexpected species differences were noticed, as BX430 is a potent a

296 ing Lp-PLA(2) are indirect and confounded by species differences; whether Lp-PLA(2) is causal in coro

297 dies emphasize the importance of considering species differences, which can result from even minor pr

298 ion, short half-lives, and a pharmacokinetic species difference with the greatest exposure measured i

299 The results indicate significant species differences with chimpanzees showing population-

300 odents, these findings highlight significant species differences, with more heterogeneity and the pot