ライフサイエンスコーパス: spectrometric

1 Theoretical Fragment Ion Mass Spectra) mass spectrometric acquisitions were performed to obtain a mo

2 Duplicate mass spectrometric analyses and confirmatory next generation

3 Mass-spectrometric analyses confirmed that conversion is perf

4 raphy is a core component of almost all mass spectrometric analyses of (bio)molecules.

5 Tandem mass spectrometric analyses of deuterated congeners and MS(3)

6 Large-scale microarray and mass spectrometric analyses revealed significant up-regulatio

7 Therefore, we performed quantitative mass spectrometric analyses to define the epitopes formed in

8 We used immunoprecipitation followed by mass spectrometric analyses to evaluate the presence of tau36

9 e users to perform complex quantitative mass spectrometric analyses with ease.

10 ecause of the high-throughput nature of mass spectrometric analyses, the interpretation of these chro

11 sdom that detergents are deleterious to mass spectrometric analyses, the presence of Tween-20 did not

12 ibodies and patients' serum followed by mass spectrometric analyses.

13 gy collisional dissociation) multistage mass spectrometric analysis (HCD-MS(n)) and ETD (electron tra

14 amide hydrogen-deuterium exchange with mass spectrometric analysis (HDX-MS) coupled with proteolytic

15 labeling combined with sensitive tandem mass spectrometric analysis allowed integrated synthesis rate

16 ogen for additional investigation using mass spectrometric analysis and electron microscopy.

17 Performed mass spectrometric analysis and molecular modeling allowed us

18 between BtAdVs and CAdVs, we conducted mass spectrometric analysis and single-particle cryo-electron

19 Mass spectrometric analysis identified apolipoprotein(a) (apo

20 cing peptide (AIP) was responsible, and mass spectrometric analysis identified the S. caprae AIP as a

21 Mass spectrometric analysis identified USP14 interaction with

22 Mass spectrometric analysis indicated that 628 cell-lysate pr

23 Arraying of single cells for mass spectrometric analysis is a considerable bioanalytical c

24 in limitation to the sensitivity of the mass spectrometric analysis of (99)Tc is the background of it

25 degradation products were identified in mass spectrometric analysis of 29 of 33 arthropathic patients

26 ), was developed for flame atomic absorption spectrometric analysis of aluminum (Al) and chromium (Cr

27 A holistic, nontargeted mass spectrometric analysis of any herbal material and prepar

28 mpling/ionization method for the direct mass spectrometric analysis of biological samples at ambient

29 analytical technique allowing for rapid mass spectrometric analysis of biological samples with little

30 Mass spectrometric analysis of carbonyl compounds in fecal sa

31 Mass spectrometric analysis of cell extracts identified 352 p

32 Mass spectrometric analysis of conditioned medium from immort

33 unction with chemical cross-linking and mass spectrometric analysis of conformational changes to GAFa

34 Mass spectrometric analysis of GAG isomers, in particular hig

35 Our mass spectrometric analysis of homomeric and heteromeric TRPM

36 advances in methods for enrichment and mass spectrometric analysis of intact glycopeptides have prod

37 Mass spectrometric analysis of Ire1 expressed in Escherichia

38 Finally, using a mass spectrometric analysis of secreted proteins, we demonstr

39 eted, high throughput, and quantitative mass spectrometric analysis of single cells from cell suspens

40 e nanofluidic technologies have enabled mass spectrometric analysis of single cells, these measuremen

41 RNA sequencing and mass spectrometric analysis of SPRIGHTLY-expressing cells rev

42 Mass spectrometric analysis of the anionic products of intera

43 Mass spectrometric analysis of the anionic products of intera

44 Mass-spectrometric analysis of the enzymatic hydrolysis produ

45 Using mass spectrometric analysis of the isolated VEGF-C-cleaving a

46 on the digestibility were determined by mass spectrometric analysis of the modified beta-lactoglobuli

47 We conducted a comprehensive mass spectrometric analysis of the N-glycosylation profiles o

48 we performed affinity purification and mass spectrometric analysis of the protein microenvironment o

49 Raman spectroscopic and mass spectrometric analysis of the reaction solutions reveale

50 Mass spectrometric analysis of the secretome of P. aeruginosa

51 Mass spectrometric analysis of the starting octasaccharide mi

52 d for their subsite specificities using mass spectrometric analysis of their products when acting on

53 Through mass spectrometric analysis of ubiquitylated proteins affinit

54 A mass spectrometric analysis platform has been developed to de

55 ant role of GNRs as semiconductors, the mass spectrometric analysis provides a readily available tool

56 can subsequently be subjected to rapid mass spectrometric analysis providing insights into the skin

57 Mass spectrometric analysis revealed binding of ZNF768 to Elo

58 Mass spectrometric analysis revealed significant differences

59 Mass spectrometric analysis revealed that the RxLR sequence o

60 ypsinolysis followed by high resolution mass spectrometric analysis reveals that Ub chain branching c

61 of milk proteins by kefir grains, with mass spectrometric analysis showing the release of 609 protei

62 the potential to be translated to other mass spectrometric analysis techniques, including MALDI and v

63 w by model organic reactions and qualitative spectrometric analysis that a nonpolar pyrrole adduct is

64 d with a fragment separation method and mass spectrometric analysis to compare their secondary struct

65 reduce complexity of mixtures or tandem mass spectrometric analysis to conduct structural elucidation

66 stabilize regiospecificity, and tandem mass spectrometric analysis to identify and quantify regioiso

67 es, enzyme assays, Western blotting and mass spectrometric analysis to monitor and quantify the invol

68 om volume-limited samples, each type of mass spectrometric analysis uncovers only a portion of the co

69 followed by enzyme digestion and tandem mass spectrometric analysis using an LC-MS/MS system coupled

70 d by a combination of NMR spectroscopy, mass spectrometric analysis, and computational modeling using

71 The concept of direct mass-spectrometric analysis, especially exploited by ambient

72 Ahead of online mass spectrometric analysis, field asymmetric ion mobility sp

73 Here, using mass spectrometric analysis, it is demonstrated that the C te

74 After sample preparation and mass-spectrometric analysis, peptide intensity ratios between

75 nt capture, co-immunoprecipitation, and mass spectrometric analysis, we identified a subset of HDAC8

76 Using yeast two-hybrid and mass-spectrometric analysis, we report that mDia1 has a stage

77 quantified using a targeted HPLC tandem mass spectrometric analysis.

78 istry with peptidomics information from mass spectrometric analysis.

79 mined by chromatographic separation and mass spectrometric analysis.

80 ed by immunohistochemistry staining and mass spectrometric analysis.

81 nd biofluid electrolytes for quantiatve mass spectrometric analysis.

82 13)C NMR, UV-Vis spectroscopies and via mass spectrometric analysis.

83 ization with online chemical ionization mass spectrometric analysis.

84 ation of glycopeptides and their tandem mass spectrometric analysis.

85 pheric pressure chemical ionization and mass spectrometric analysis.

86 glycoproteins in whole cell lysates for mass spectrometric analysis.

87 sitives are small owing to the use of a mass spectrometric analysis.

88 that occur during sample preparation or mass spectrometric analysis.

89 ng mice and followed by biochemical and mass spectrometric analysis.

90 ing several intermediates identified by mass spectrometric analysis.

91 ported, but could not yet be coupled to mass spectrometric analysis.

92 e as multiply charged ions suitable for mass spectrometric analysis.

93 rapid affinity purification followed by mass spectrometric analysis.

94 Spectroscopic and mass spectrometric analytical techniques were used to charact

95 We provide mass spectrometric and biochemical evidence of an association

96 learning classifier was also developed using spectrometric and chromatographic variables to minimize

97 cant improvements to total selectivity (mass spectrometric and chromatographic), peak identification,

98 Mass spectrometric and crystallographic studies of Pt(II) bin

99 Mass spectrometric and immunochemical analyses showed that NT

100 Additionally, mass spectrometric and immunochemical analyses showed that th

101 Combined mass spectrometric and infrared spectroscopic analyses of in

102 of this ion source is demonstrated with mass spectrometric and ion mobility measurements of acetone,

103 st catalysis cycle were corroborated by mass spectrometric and NMR experiments, thereby additionally

104 Our mass spectrometric and spectroscopic studies are accompanied

105 and a low-P sandy soil by combining advanced spectrometric and spectroscopic techniques to introduce

106 Biochemical, mass spectrometric, and mutational analyses revealed that CM1

107 Light-scattering, mass spectrometric, and nuclear magnetic resonance characteri

108 Our high-resolution mass spectrometric approach can unambiguously differentiate b

109 stems in aqueous environments through a full spectrometric approach combined with a simulation and da

110 eport the development of a quantitative mass spectrometric approach combined with microfluidic techno

111 For the first time we present a mass spectrometric approach employing an ambient ionisation p

112 Notably, a mass spectrometric approach showed that ARH3-deficient mouse

113 We present a mass spectrometric approach to characterize and monitor the i

114 Using a large-scale mass spectrometric approach, here we perform quantitative sec

115 Here, using a site-specific mass spectrometric approach, we reveal the glycan structures

116 targeted, liquid chromatography-coupled mass spectrometric approach.

117 Herein, we highlight mass spectrometric approaches commonly applied to identify in

118 etic, biochemical, and highly sensitive mass spectrometric approaches, we identified an alternative m

119 y-multiple reaction monitoring (LC-MRM) mass spectrometric approaches.

120 lipidomics-based liquid chromatographic-mass spectrometric assay for phospholipases A(2) to perform i

121 Herein, the first chiral dopant-based mass spectrometric assay, with its foundation rooted in the C

122 using either flow cytometry or a novel mass spectrometric assay.

123 Furthermore, both spectrometric assays (total phenolic content and radical

124 studied in patients using quantitative mass-spectrometric assays.

125 etric instrumentation was performed for mass spectrometric assessment of trueness.

126 mechanistic studies including those of mass spectrometric back reaction screening experiments, which

127 Here, we provide mass spectrometric-based evidence to show that metallodrug in

128 Here, we report chromatographic and mass spectrometric behavior of 904 authentic standards collec

129 of specific compound classes and their mass spectrometric behaviour, and poses the risk of missing u

130 d considerable momentum in the field of mass spectrometric biomolecule analysis, including proteomics

131 Using these improved mass spectrometric capabilities, we detected and quantified 2

132 Mass spectrometric characterisation identified novel MUPs in

133 pon APCI, and therefore enable accurate mass spectrometric characterization of complex mixtures of sa

134 Mass spectrometric characterization of KRAS expressed in mamm

135 Mass spectrometric characterization of McrA from the methanog

136 curves, herein we present a coulometric mass spectrometric (CMS) approach for absolute protein quanti

137 e been observed and characterized under mass spectrometric conditions.

138 t analysis in real time-high resolution mass spectrometric (DART-HRMS) analysis of ethanol suspension

139 , proteomic sample preparation (5-7 d), mass spectrometric data acquisition (2 d), and proteomic data

140 Acquired mass spectrometric data argues against formation of oligomers

141 pretreated samples showed that not only mass spectrometric data can be obtained by electrochemistry-m

142 High-resolution mass spectrometric data collection was conducted in a dual io

143 iently searching liquid chromatographic/mass spectrometric data for unknown compounds has been develo

144 e I/II biotransformation prediction and mass-spectrometric data mining.

145 ols and ready-made workflows for common mass spectrometric data processing tasks, which enable users

146 Simplify combines biological and mass spectrometric data sets and uses an "activity index" to

147 ly available for untargeted analysis of mass spectrometric data sets, it does not always identify met

148 However, mass spectrometric data typically contain large amounts of mi

149 data fusion methodology of spectroscopic and spectrometric data was performed, the prediction efficie

150 Mass spectrometric data was processed using the laboratory-bu

151 olydispersity index determined from the mass spectrometric data were in line with both the label valu

152 methods and correlation of spectroscopic or spectrometric data with bioactivity results are known to

153 teria addressing (1) the quality of the mass spectrometric data, (2) the confidence of peptide identi

154 reanalysis of their NMR spectroscopic and MS spectrometric data, comparison of this data with those r

155 ntify pGlu, in agreement with available mass spectrometric data.

156 s examined on simulated as well as real mass spectrometric data.

157 liquid chromatographic high-resolution mass spectrometric data.

158 ing approaches is the complexity of the mass spectrometric data.

159 gas chromatography with time-of-flight mass spectrometric detection (GC(3)/TOFMS) is described.

160 gas chromatography with time-of-flight mass spectrometric detection (GCxGC/TOFMS) proved to be appro

161 n in rice using ion chromatography with mass spectrometric detection (IC-ICP-MS), covering the main r

162 r coupled to inductively coupled plasma mass spectrometric detection (ICP-MS).

163 ar beam (CMB) instruments with rotating mass spectrometric detection and time-of-flight analysis, esp

164 interaction screening assays employing mass spectrometric detection are widely used in early stage d

165 ysis coupled to gas chromatography with mass-spectrometric detection in selected ion monitoring mode

166 concentrations in their brains using a mass spectrometric detection method developed for this purpos

167 t a peptide binding method coupled with mass spectrometric detection of bound peptide can quantify mA

168 y assay that allows the high-throughput mass-spectrometric detection of enzyme activity in complex ma

169 ytes with excellent chromatographic and mass spectrometric detection properties.

170 tion, microfluidic sample handling, and mass spectrometric detection through signal ion emission reac

171 elected reaction monitoring (SRM) based mass spectrometric detection to quantify a positron emission

172 ted, using liquid chromatography-tandem mass spectrometric detection, in order to accurately determin

173 al composition distribution (CCD), with mass spectrometric detection, is described.

174 -performance liquid chromatography with mass spectrometric detection, whereas total phenolic content

175 n ionization time-of-flight (MALDI-TOF) mass spectrometric detection-are attractive analytical approa

176 rformance liquid chromatographic-tandem mass spectrometric detection.

177 le benefits when combined with accurate mass spectrometric detection.

178 liquid chromatography (UPLC), both with mass spectrometric detection.

179 samples followed by flame atomic absorption spectrometric detection.

180 l flow injection system was designed for the spectrometric determination of the analyte (=344nm).

181 versatile ambient ionization source for mass-spectrometric determinations of polar and nonpolar analy

182 evelop rapid, large-scale, and parallel mass spectrometric drug screens.

183 sodium or proton pump, with noncovalent mass-spectrometric, electrophysiological, and flash photolysi

184 plex was also confirmed by electrospray mass spectrometric (ESI MS) experiments.

185 (-) hampers the electrospray ionization mass spectrometric (ESI-MS) analysis.

186 Genetic, pharmacological and mass spectrometric evidence in vivo as well as in vitro confi

187 rometric, spectroscopic, chromatographic and spectrometric experiments.

188 and products of ACE through a series of mass-spectrometric experiments.

189 any of the 4 same foods.A total of 249 mass spectrometric features showed a positive dose-dependent

190 ds for P(A) analysis based on enzymatic mass spectrometric fingerprinting and in silico simulations.

191 Here, we describe an enzymatic/mass spectrometric fingerprinting method to analyze the FA of

192 Applicability of the obtained mass spectrometric fingerprints for food authentication was e

193 r predicted hidden states, we use rapid mass spectrometric footprinting and confirm our models' predi

194 gas phase using two differential tandem mass-spectrometric fragmentation methods, such as collision-i

195 A gas chromatography-mass spectrometric (GC-MS) method was utilized for the separa

196 channel them into a gas chromatography/mass spectrometric (GC/MS) system for analysis.

197 ional assessment of barrier parameters, mass spectrometric global proteomic analysis and quantitative

198 Here, we combine comprehensive mass spectrometric glycan sequencing and molecular dynamics s

199 inductively coupled plasma optical emission spectrometric (ICP-OES).

200 However, the mass spectrometric identification and characterization of cro

201 oredoxin in E. coli cells, allowing for mass spectrometric identification of interacting proteins and

202 explore the utility of this reagent in mass spectrometric identification of specific functionalities

203 Here we report on the mass spectrometric identification of the OTULIN interactor SN

204 iotin tag for subsequent enrichment and mass spectrometric identification of the receptor or other ho

205 e, using affinity protein purification, mass spectrometric identification, and confocal immunofluores

206 A modified isotope dilution mass spectrometric (IDMS) method treating the silicon as the

207 ix-assisted laser desorption/ionization mass spectrometric imaging (MALDI-MSI) of agarose micro-beads

208 Advanced mass spectrometric imaging and surface analysis techniques we

209 Furthermore, we performed mass spectrometric imaging combined with fluorescence in situ

210 atibility of this protocol with various mass spectrometric imaging methods including matrix-assisted

211 rison between tandem and time-of-flight mass spectrometric instrumentation was performed for mass spe

212 Mass spectrometric investigation indicates the presence of he

213 tion followed by liquid chromatographic/mass spectrometric (LC/MS) analysis was used to locate "twin"

214 emonstrate that combinatory AQbD-guided mass spectrometric/liquid chromatographic optimization signif

215 e double-spike procedure, only a single mass spectrometric measurement is required, which improves an

216 on of a surrogate peptide combined with mass spectrometric measurement of the oxidation yield.

217 Mass spectrometric measurements both by electrospray ionizati

218 Additional mass spectrometric measurements of 20 different organic compo

219 Mass spectrometric measurements revealed that expression of Y

220 asma calcium phosphate crystallization using spectrometric measurements, and its correlations with ef

221 beticola and E. fawcettii coupled with mass spectrometric metabolite analyses confirmed their roles

222 A major bottleneck of mass spectrometric metabolomic analysis is still the rapid de

223 obtained by inductively coupled plasma mass spectrometric method and no significant difference betwe

224 aser desorption/ionization (SALDI)-type mass spectrometric method for analysis and imaging, can diffe

225 A sorption-spectrometric method for determination of the anionic sy

226 A new mass spectrometric method for evaluating metabolite formation

227 ods in recent years, there is no simple mass spectrometric method for identification and de novo dete

228 Finally, we established a mass spectrometric method for quantifying the incorporated ar

229 is study were to develop a quantitative mass spectrometric method for selected betainized compounds i

230 ry sampling electrothermal atomic absorption spectrometric method is proposed for the determination o

231 We report here a mass spectrometric method that is able to identify and distin

232 Here we developed a mass spectrometric method to interrogate incorporation of sel

233 to apply a liquid chromatography-tandem mass spectrometric method to investigate the presence of 20 m

234 tion of a highly accurate and sensitive mass spectrometric method, no trace of BMAA was detected in t

235 odel), were identified by an innovative mass spectrometric method, SNOTRAP.

236 Atmospheric pressure sampling mass spectrometric methods are ideal platforms for rapidly an

237 88.6 mumol/h/kg) (P = 0.165) by the two mass spectrometric methods in HC.

238 ted or largely replaced by a variety of mass spectrometric methods in recent years, there is no simpl

239 02.2 mumol/h/kg) (P = 0.247) by the two mass spectrometric methods in SM and 93.7 mumol/h/kg (IQR, 79

240 peroxides in association with sensitive mass spectrometric methods should constitute powerful tools f

241 ng tool, this approach could supplement mass spectrometric methods that may only be applicable at low

242 Two liquid chromatography-tandem mass spectrometric methods were developed and validated to de

243 Compared to other mass spectrometric methods, the developed assays require less

244 Using two different tandem mass spectrometric methods, we measured the isotopic enrichme

245 cal sample cohorts and across different mass spectrometric methods.

246 by single crystal X-ray diffraction and NMR spectrometric methods.

247 rent in SM than in HC by the respective mass spectrometric methods: 93.2 mumol/h/kg of body weight (I

248 Comprehensive mass spectrometric (MS) analyses were conducted to characteri

249 eparation method, the addition to it of mass spectrometric (MS) analysis, and recent improvements in

250 for their selective enrichment prior to mass spectrometric (MS) analysis.

251 ance glycans and glycopeptides prior to mass spectrometric (MS) analysis.

252 Mass spectrometric (MS) characterization of these molecules a

253 Here, we present a workflow that allows mass spectrometric (MS) identification of proteins in direct

254 borious and time-consuming process, and mass spectrometric (MS) imaging techniques, which show great

255 A highly sensitive mass spectrometric (MS) method was developed and validated to

256 Sensitive and selective mass spectrometric (MS) techniques coupled to ultrahigh perfo

257 Next-generation mass spectrometric (MS) techniques such as SWATH-MS have subs

258 n be applied for the concomitant tandem mass spectrometric (MS/MS) analysis of nine pharmaceuticals i

259 Here we report synthetic, mass spectrometric, NMR spectroscopic and quantum mechanical/

260 yover and improve liquid chromatography-mass spectrometric performance.

261 Mass spectrometric phosphoproteomic measurements further iden

262 trometry (REIMS) was used for the rapid mass spectrometric profiling of cancer cell lines.

263 This may be the first mass spectrometric profiling of polyphenol components from cu

264 As an alternative, direct mass spectrometric profiling of the mucosal metabolome provid

265 We performed a mass spectrometric proteomics characterization of BALF exosom

266 Proton Transfer Reaction Time-of-Flight Mass Spectrometric (PTR-(ToF)MS).

267 In addition, the spectrometric quality of the small sensor (size: 6.5mm i

268 talyzed depurination of DNA followed by mass spectrometric quantification of adenine.

269 orizer) parameters for high-sensitivity mass spectrometric quantification of brain tissue glutamine.

270 nalytical GLP methodology detailing the mass spectrometric quantitation of PF-05212384 dosed as a tar

271 0 muL of plasma resulted in the highest mass spectrometric response.

272 The mass spectrometric results reveal ample oxidative side reacti

273 ber of structurally similar components, mass spectrometric screens based on high-performance liquid c

274 2-AA-labeled glycans have increased mass spectrometric sensitivity for their identification and e

275 concentration, and eventually in direct mass spectrometric sensitivity.

276 get, to some degree, structure-specific mass spectrometric signals.

277 quantification from aqueous samples using a spectrometric smartphone-based system for the first time

278 f the sample's absorption spectrum using the spectrometric smartphone-based system.

279 advanced instrumental techniques, including spectrometric, spectroscopic and chromatographic methods

280 urier transform ion cyclotron resonance mass spectrometric studies, we determined that water was the

281 validated by photoaffinity labeling and mass spectrometric studies.

282 n methods have an important role in the mass spectrometric study of crude oils and other natural samp

283 This work deals with the comprehensive spectrometric study of the chlorophyll derivatives prese

284 ent a hydrogen/deuterium exchange (HDX)-mass spectrometric study of wild type and mutant COMT, compar

285 This finding is borne out by mass spectrometric survey of A152T tau phosphorylation in C.

286 erformance liquid chromatography-tandem mass spectrometric system.

287 oligomer growth can be assigned by the mass spectrometric technique.

288 ical profile of an ancient beer using modern spectrometric techniques and providing evidence for the

289 lexes are characterized with UV/Vis and mass spectrometric techniques and reaction rates with cyclohe

290 ith other ambient desorption/ionization mass spectrometric techniques like desorption electrospray io

291 ticle-phase products by high-resolution mass spectrometric techniques revealed the formation of nitro

292 We combined a range of mass spectrometric techniques to unravel the location and ext

293 imated for the first time in the kinetic and spectrometric techniques using the certified reference m

294 ation of high-resolution separation and mass spectrometric techniques were used to characterize a Br-

295 r both variants by integrating advanced mass spectrometric techniques with available electron microsc

296 TL18 was well-characterized by NMR and EI-MS spectrometric techniques.

297 s revealing excellent agreement of both mass spectrometric techniques.

298 ric pressure chemical ionization tandem mass spectrometric (UHPLC-APCI-MS/MS) method was developed fo

299 d chromatography with triple quadrupole mass spectrometric (UPLC-QqQ-MS/MS) profiling of phenolic com

300 eptides identified in current bottom-up mass spectrometric workflows, although impressive for high-th