ライフサイエンスコーパス: speculate on

1 is unexpected, O-linked ADP-ribosylation are speculated on.

2 landscape for neuronal calcium sensor-1 and speculate on a direct link between protein misfolding an

3 rganelle reported to date, which leads us to speculate on a mechanism of constraint guiding the dynam

4 These results allow us to speculate on a possible mechanism by which mutant TIMP-3

5 The authors speculate on a possible serotonergic mechanism controlli

6 We previously speculated on a potential posterior-anterior distinction

7 background in certain mtDNA-based diseases, speculates on a pathogenic role for a subset of LHON sec

8 A model is proposed that speculates on a possible role for NADPH in regulating pr

9 We speculate on additional activities required for map deve

10 Finally, we speculate on and provide testable hypotheses for novel n

11 le of TF in tumor growth and metastasis, and speculate on anticancer therapy by targeting TF.

12 ation, the origin of type II opsins has been speculated on but never tested.

13 Finally, we speculate on cross-cutting features for microbial influe

14 nique environment of the droplet surface and speculate on effects of topological constraints and phys

15 We also speculate on further pathways in nanotechnology developm

16 We also speculate on future directions in this field.

17 We also speculate on future directions in this research that are

18 Finally, we speculate on future innovation as we continue to progres

19 immune cells to the reproductive process and speculate on future lines of inquiry.

20 for the next generation of technologies, and speculate on future strategies that may be capable of ov

21 ed synthetic and integration strategies, and speculates on future directions for the field.

22 eed to have narrow ion-selective filters, we speculate on how an exchanger might evolve to show chann

23 In this Essay, I speculate on how an increase in mitochondrial activity m

24 Lastly, we speculate on how CRISPR/Cas9 can be integrated to improv

25 We also speculate on how different modes of temporal patterning

26 In addition, we discuss and speculate on how epigenetic processes are involved in cr

27 ies that go beyond cognitive subtraction and speculate on how functional imaging can be used to addre

28 of ongoing trials and their limitations, and speculate on how future trials could be made more effici

29 dies within the domain of emotions, and then speculate on how genomic and epigenetic mechanisms can m

30 Finally, we speculate on how increased adult hippocampal neurogenesi

31 etic retinopathy, its relative safety and we speculate on how it could be developed for intraocular d

32 We also speculate on how mNGS testing potentially fits into curr

33 Finally we speculate on how our conclusions imply indistinguishabil

34 I describe these developments and speculate on how our explanation of dynamic instability

35 out pattern diversification in Danio, and we speculate on how patterns in more distant teleosts may h

36 ntal features of these two approaches and to speculate on how proteomics will be useful in nephrology

37 and draw on various experimental findings to speculate on how remyelinating therapies are likely to d

38 We also speculate on how restriction factors arose, how they mig

39 system, a paradigm for efflux machinery, and speculate on how RND pumps assemble to fight diverse ant

40 g the affinity of weak interactions and also speculate on how SIRPalpha polymorphisms may have been s

41 Finally, we speculate on how technological advances will revolutioni

42 ozoal pathogen-microbiome interaction and to speculate on how that might be leveraged for treatment.

43 We also speculate on how the brain may be hardwired to receive a

44 Finally, we will speculate on how the distinct suppressor cell subsets ma

45 transmitter may drive synapse formation, and speculate on how the environment of the developing brain

46 Our results allow us to speculate on how the flanking domains are organized arou

47 phenomena distributed in space and time and speculate on how the principle of spatial heterogeneity

48 ntext of immunity to influenza infection and speculate on how the simultaneous evolutionary races of

49 We also speculate on how these effects might alter phenotypes, f

50 en useful to explain chromosome biology, and speculate on how they might be used in the future.

51 e for CNS-compartmentalized immune cells and speculate on how this impacts disease progression for MS

52 n about the function of calcium channels, we speculate on how this missense mutation leads to the com

53 also consider the data on Ang1 receptors and speculate on how to maximize therapeutic benefit by targ

54 Here, we draw upon emerging studies to speculate on how variants of lncRNAs might play a role i

55 es in stress-related depression behavior and speculates on how currently understood mechanisms contri

56 thetic chromosome construction in plants and speculates on how they might be applied to various uses

57 This question is addressed here by speculating on how the current repertoire of recombinase

58 en force-generation mechanisms and finish by speculating on how they may have evolved.

59 We also speculate on important questions for the future.

60 enzyme is known, but the mechanism, although speculated on, is not resolved.

61 a view on some directions for the field and speculate on its future.

62 flow on a Riemannian [Formula: see text] and speculate on its implications concerning Tao's approach

63 istate model of transcription regulation and speculate on its role in the dynamic repression of the e

64 ective of the local economics, the model can speculate on its timing based on the status of the infec

65 reatment, and outcome of this condition, and speculating on its nosological status vis-a-vis the syst

66 d to block AA and DHA oxidation, we close by speculating on likely areas of future research directed

67 t understanding of T cell biology in ASD and speculate on mechanisms behind their dysregulation.

68 ratogenic effect on the developing fetus and speculate on mechanisms by which WFS might affect neural

69 r caveolae as a specialized lipid domain and speculate on mechanisms that link changes in caveolar sh

70 present in maize provides an opportunity to speculate on mechanisms that might lead to heterosis.

71 Finally, we speculate on mechanisms to explain why such a complex da

72 We also speculate on more general roles that APCs may play in cy

73 The authors speculate on multiple reasons for the underuse of these

74 to which characterized plant lncRNAs fit and speculate on new avenues of research that may uncover ye

75 cific interactions within and between sexes, speculate on novel mechanisms, and suggest future resear

76 have been shown to impinge on mTOR, we also speculate on other signal-transduction pathways that may

77 on studies using patient samples as well as speculate on pathways that can be targeted to more holis

78 -induced intestinal mucositis, and GVHD, and speculate on possibilities of therapeutically targeting

79 alization, and function of zDHHC enzymes and speculate on possible effects of PTMs that have emerged

80 review, we address these recent advances and speculate on possible future developments.

81 activities and excitement in this area, and speculate on possible future directions.

82 Finally, we briefly speculate on possible future XPCS experiments at new syn

83 s could be regulated by neuronal signals and speculate on possible mechanisms for such regulation.

84 stration of potassium regulation of WNKs and speculate on possible physiological roles.

85 coyotes emerged over several decades and we speculate on possible processes (e.g., learning and sele

86 e formation of the preinitiation complex and speculate on possible protein-protein interactions.

87 ase apoprotein binds numerous metal ions, we speculate on possible roles for the UreD, UreF, and UreG

88 We also speculate on possible scenarios of allergen antigen pres

89 We speculate on possible scenarios that could have led to t

90 We speculate on possible ways to reduce the nonindependence

91 n the idiopathic inflammatory myopathies and speculates on possibly useful novel approaches for the f

92 translate an input into various outputs, and speculate on potential applications and directions for t

93 Additionally, we speculate on potential future applications and explore t

94 in quiescent cells from diverse contexts and speculate on potential other roles they may play, such a

95 the combined imaging/penetration results, we speculate on potential sites of cholinergic action in th

96 rrent knowledge on ADAMTS13 conformation and speculate on potential triggers inducing conformational

97 n the field of covalent network polymers and speculates on potential future directions.

98 We close by speculating on potential functions of DNL in physiology

99 Finally, we speculate on preventive and therapeutic strategies that

100 will focus on the Wnt receptor complex, and speculate on recent discoveries about ring finger protei

101 ere, we discuss these recent discoveries and speculate on some of the many unknowns regarding Restric

102 to their notable achievement and reflect and speculate on some of the scientific and personal nuances

103 To that end, a final section of the article speculates on specific ways that these trends are likely

104 s within a general plant biology context and speculate on the answers to some remaining questions.

105 atient with class III-IV lupus nephritis and speculate on the association between invasive Moraxella

106 We speculate on the basis of these results that the three a

107 n and pathogenesis of autoimmune disease and speculate on the benefit for probiotic therapies against

108 asticity in target gene selection by MYC and speculate on the biochemical and genomic contexts in whi

109 One can speculate on the biological advantage of exendin-4 to th

110 xistence of channels in transporters, and we speculate on the biological significance of this newly u

111 seased human tissues were used previously to speculate on the causes of periodontitis and to describe

112 ship of structure to biological function and speculate on the complex origin of these crucial regulat

113 r two longer wavelength cone systems, and we speculate on the consequences for color processing in th

114 We speculate on the contribution of these similar mutations

115 In this review, we speculate on the critical importance of immune interfere

116 We also discuss current limitations and speculate on the developments that are necessary to adva

117 zation between metalated As(CSL9C)(3) and to speculate on the differential basis of Hg(II) binding in

118 We speculate on the effect of Ser-639 phosphorylation on th

119 Finally, we speculate on the effects this revision will have on the

120 herapeutics, summarize progress to date, and speculate on the eventual utility of such agents in the

121 In this Comment we speculate on the evolution of recent advances made and d

122 porters in normal physiology and disease and speculate on the evolutionary origins of RBG proteins in

123 We also speculate on the existence of membrane-associated conden

124 f the evasion mechanisms currently known and speculate on the existence of others not yet identified.

125 For example, we can speculate on the existence of pressure-induced polarity

126 tion of resistance mutations, leaving one to speculate on the fate of these mutants once the antibiot

127 Finally, we speculate on the functional significance of these divers

128 s approaches used to identify these Acrs and speculate on the future for Acr discovery.

129 open questions that remain in the field and speculate on the future of drug-microbiome-autoimmune di

130 review themes emerging from such studies and speculate on the future of immunoimaging.

131 s methodological advances to prior work, and speculate on the future of this important problem.

132 We speculate on the generality of this molecular cause of a

133 We speculate on the implications of recent research in this

134 Finally, we speculate on the implications of the specificity of the

135 We speculate on the implications of these observations for

136 Finally, we speculate on the implications of this pattern of connect

137 the predetermined mode is the release and we speculate on the importance of these two processes in te

138 We speculate on the importance of this interaction for FN f

139 Finally, we speculate on the induction of phage-encoded DNase (Spd1)

140 utophagy in innate and adaptive immunity and speculate on the intriguing interplay between these two

141 emerging views on lipid droplet biology and speculate on the major advances to come.

142 marily on the discovery of riboswitches, and speculate on the major challenges facing researchers in

143 We also speculate on the mechanisms by which hypertrophic cardio

144 As a consequence, we can speculate on the mechanisms of DISC1 action and possible

145 hronous activity in the rodent neocortex and speculate on the mechanisms that drive its eventual desy

146 We speculate on the molecular sensing pathways in cartilage

147 We speculate on the neural mechanisms that link sampling of

148 Furthermore, we speculate on the observed differences in particle size a

149 and effects of senescence in macrophages and speculate on the ontogeny of the senescent-like state in

150 perspectives, highlight new discoveries, and speculate on the opportunity created by merging the rese

151 e than single interception attachers, and we speculate on the origin of this change in alpha.

152 We also speculate on the possibility of a third level, reporting

153 n this review, we discuss these advances and speculate on the possibility of targeting these events t

154 We also speculate on the possible links between X colocalization

155 We speculate on the possible role that FSA may play in the

156 We speculate on the possible roles of phosphoinositides in

157 We speculate on the possible significance of KlcB-KorA hete

158 We also speculate on the possible significance of this model for

159 venues for improving prediction accuracy and speculate on the possible use of WGP to prospectively id

160 by pathogens for their own transmission and speculate on the potential of ERM proteins for regulatin

161 We speculate on the potential reasons for MAIT cell conserv

162 perception on carpel development lead us to speculate on the potential role of light-regulated mecha

163 We also speculate on the potential role of NETs in the pathogene

164 perfusion injury and preconditioning, and to speculate on the potential role of preconditioning in th

165 Finally, we speculate on the potential role of quadruplex formation

166 idence for NsrR as a global regulator and to speculate on the recent controversy over its NO sensing

167 stence and function of the interactions, and speculate on the regulatory roles that such long-distanc

168 We speculate on the relationship between the two systems an

169 Here we speculate on the respective contributions to autoimmunit

170 o the pathogenesis of Burkitt's lymphoma and speculate on the role of Epstein-Barr virus.

171 We also speculate on the role of ethylene in postsubmergence rec

172 In this article, we describe and speculate on the role of selective cell death during mat

173 s and the mechanisms of redox signaling, and speculate on the role that mitochondrial anisotropies mi

174 We speculate on the role that this novel protein could play

175 up to the final product formation step, and speculate on the roles of the enzymes in the lifecycle o

176 With reference to the capsid structure, we speculate on the roles of these residues in capsid stabi

177 the associated conceptual advancements, and speculate on the shape novel theories of the cortex may

178 We speculate on the significance in terms of a potential fu

179 Here, I discuss and speculate on the social and evolutionary implications of

180 Lastly, I will speculate on the theoretical and practical implication o

181 We also speculate on the threat to specific populations followin

182 We speculate on the various mechanisms by which this may be

183 In our article, we have speculated on the activity of an oral-gut-estrobolome ax

184 Previous authors have speculated on the functional importance of initial doubl

185 body perception from birth [13], others have speculated on the importance of postnatal experience [14

186 civic centre of Knossos, archaeologists have speculated on the origin of the founders of the civiliza

187 Previous work has speculated on the phenomenological similarities between

188 st the 16th century, many investigators have speculated on the presence of a specialized muscle in th

189 It was speculated, on the basis of kinetic evidence, that VA*+

190 henotyping" of electronic health records and speculates on the impact such computational capabilities

191 technologies are highlighted and the author speculates on the importance of biosensors as a ubiquito

192 motifs that have been identified so far and speculates on the importance of their role in determinin

193 link between circadian clock and cancer, and speculates on the possible connections at the epigenetic

194 The present study speculates on the potential gain we can expect of a furt

195 he animal and early clinical experience, and speculates on the potential of genetic manipulation of b

196 Only a theory that speculates on the psychological processes provides testa

197 low nanomolar nonpeptidic MV inhibitors and speculates on the role of the CF 3 functionality.

198 he different methods and their findings, and speculates on the value of combining these techniques to

199 Speculating on the answers to these questions is as stim

200 ociated with survivin-targeted therapies and speculating on the future strategies to surmount these i

201 ation was neglected, with subsequent studies speculating on the role of doxycycline resistance in con

202 At the end, we conclude by speculating on the role of long range optical rulers in

203 ical trial and multiple published hypotheses speculating on the role of this host receptor in viral i

204 orticofugal pathways from Layers 5 and 6 and speculate on their functional contributions to neural pr

205 dysregulation of promoter-enhancer hubs and speculate on their functional role in pathogenesis.

206 tagenomics, discuss their pros and cons, and speculate on their future directions.

207 erature that illustrate these principles and speculate on their implications for further study.

208 s distinguishable by regulatory proteins and speculate on their possible consequences.

209 context of intestinal immune regulation and speculate on their potential clinical significance.

210 review viral mechanisms to regulate the APC, speculate on their roles during infection, and identify

211 l and ecological features of charophytes, we speculated on their possible use as biomonitors and bior

212 al roles of small RNAs in immune biology and speculates on their potential participation in lymphogen

213 t microbiota composition to IBD pathogenesis speculating on their possible implications in disease ex

214 ration for both rheological properties, thus speculating on their use as potential rheo-markers, i.e.

215 We discuss these models and speculate on therapeutic approaches.

216 We speculate on three possible candidate genes for familial

217 uclear localization signal (NLSI) in p53 and speculated on two additional sites termed NLSII and NLSI

218 He further speculates on ways to cope with this dissolution of mean

219 of electrostatics to CH-pi interactions and speculate on what our observations imply about the absol

220 studied eukaryotic Pif1 family helicases and speculate on what roles such enzymes may play in bacteri

221 perimental evolution have told us so far and speculate on where progress might be made in the future.

222 We speculate on why an RNase III deficiency could globally

223 We speculate on why nodes of Ranvier contain a mechanosensi

224 We speculate on why stochasticity is advantageous-and even

225 der than expected from simple estimates, and speculate on why this might be.

226 d discuss their functional significance, and speculate on why this situation might have evolved.