ライフサイエンスコーパス: spermiogenesis

1 components during spermatid differentiation (spermiogenesis).

2 h protamine for compaction into sperm during spermiogenesis.

3 ation defects, indicating a function in late spermiogenesis.

4 ependent involvement of the Pygo2 protein in spermiogenesis.

5 multiple tissue membranes or act upstream of spermiogenesis.

6 expressed in the testis, specifically during spermiogenesis.

7 erived from transcription that precedes late spermiogenesis.

8 s coevolved to play cooperative roles during spermiogenesis.

9 teins play an earlier structural role during spermiogenesis.

10 centriolar adjunct and acrosomal cap during spermiogenesis.

11 ous sheath, a cytoskeletal element unique to spermiogenesis.

12 e expression of its target mRNAs involved in spermiogenesis.

13 otile spermatozoa through a process known as spermiogenesis.

14 eton-based cell-morphological changes during spermiogenesis.

15 that Rnf17 encodes a novel key regulator of spermiogenesis.

16 is required for normal meiotic division and spermiogenesis.

17 erm cells) in a developmental cascade termed spermiogenesis.

18 modulator gene are sterile due to failure of spermiogenesis.

19 ix5 for both spermatogenic cell survival and spermiogenesis.

20 other chromosome processes during mammalian spermiogenesis.

21 teins, and subsequently by protamines during spermiogenesis.

22 or late pachytene stages of meiosis or early spermiogenesis.

23 histone-to-protamine transition in mammalian spermiogenesis.

24 -binding protein and is essential for normal spermiogenesis.

25 the phenotype of CREM, a master regulator of spermiogenesis.

26 for this novel CLIP derivative during mouse spermiogenesis.

27 single large acrosomic vesicle at step 3 of spermiogenesis.

28 ce are sterile because of a severe defect in spermiogenesis.

29 made from a segment of HIV, had no effect on spermiogenesis.

30 criptional regulation of genes essential for spermiogenesis.

31 nd reorganization of the cytoskeleton during spermiogenesis.

32 such repressed mRNAs become activated during spermiogenesis.

33 C scaffolding protein, during the process of spermiogenesis.

34 e formation of parallel actin bundles during spermiogenesis.

35 a spermatid signaling pathway that initiates spermiogenesis.

36 s a transient structure that develops during spermiogenesis.

37 t sequentially involve mitosis, meiosis, and spermiogenesis.

38 me interval corresponds to the initiation of spermiogenesis.

39 nslational control of the TSOD-1 mRNA during spermiogenesis.

40 ells and is translationally regulated during spermiogenesis.

41 ) that is specifically expressed during late spermiogenesis.

42 ses (DNases) that elevate DNA damage in late spermiogenesis.

43 transcriptional regulator of stage-specific spermiogenesis.

44 CCDC146 expression starts during late spermiogenesis.

45 t for the histone-to-protamine transition of spermiogenesis.

46 eins, which are exclusively expressed during spermiogenesis.

47 altered mice post-meiosis, reflect abnormal spermiogenesis.

48 heir cytoplasmic compartmentalization during spermiogenesis.

49 licins prevents proper calyx assembly during spermiogenesis.

50 l reprogramming with LLPS as a key driver in spermiogenesis.

51 INE1 retrotransposon silencing and defect in spermiogenesis.

52 hylation promotes histone replacement during spermiogenesis.

53 tion specifically in round spermatids during spermiogenesis.

54 n perinuclear theca proteins required during spermiogenesis.

55 disrupts its interactions with SPEM1 during spermiogenesis.

56 odal decomposition during the late stages of spermiogenesis.

57 n the final phase of spermatogenesis, called spermiogenesis.

58 ruit gamma-TuRCs to organize MTs and support spermiogenesis.

59 ing the histone-to-protamine exchange during spermiogenesis.

60 t fails to support round spermatids to enter spermiogenesis.

61 developing flagellum to the head during late spermiogenesis.

62 repressed and chromatin is compacted during spermiogenesis.

63 of the seminiferous epithelium orchestrating spermiogenesis.

64 the maintenance of mitotic cells and normal spermiogenesis.

65 rects gene expression and the progression of spermiogenesis.

66 enesis, post-transcriptional regulation, and spermiogenesis.

67 ositively regulate target genes required for spermiogenesis.

68 of a subset of postmeiotic genes to regulate spermiogenesis.

69 icipating in chromatin remodeling during rat spermiogenesis.

70 maturation of haploid male germ cells called spermiogenesis.

71 s well as meiotic cell cycle progression and spermiogenesis.

72 hromatin remodeling process during mammalian spermiogenesis.

73 found defects in chromatin remodeling during spermiogenesis.

74 to subsequent disruptions in meiosis II and spermiogenesis.

75 n is of critical importance during mammalian spermiogenesis.

76 gamete fusion, oocyst shedding, mitosis and spermiogenesis.

77 oral expression of haploid cell genes during spermiogenesis.

78 onial mitosis, meiosis of spermatocytes, and spermiogenesis.

79 osis, is stably maintained during subsequent spermiogenesis.

80 te structure and function and the control of spermiogenesis.

81 edicted to play an indispensable role during spermiogenesis.

82 equired for spermatid differentiation during spermiogenesis.

83 rotein-to-protamine chromatin remodelling in spermiogenesis.

84 Male mutant mice are sterile with defects in spermiogenesis.

85 te an indispensable role for TSSK 1 and 2 in spermiogenesis.

86 to be degenerated and non-functional during spermiogenesis [5, 6].

87 hromatin remodeling process during mammalian spermiogenesis, 90% of the nucleosomal histones are repl

88 WI family member, is required for initiating spermiogenesis, a process that transforms round spermati

89 Spermiogenesis, a process through which haploid male ger

90 Mammalian spermiogenesis, a process where haploid male germ cells

91 of TIF2 in Sertoli cells, including abnormal spermiogenesis, age-dependent degeneration of seminifero

92 nthesized as a precursor (pro-AKAP82) during spermiogenesis, an antiserum was raised against a peptid

93 ariants containing CR-B are expressed during spermiogenesis and assemble into the fibrous sheath of t

94 Protamines are synthesized during spermiogenesis and condense the paternal genome into a t

95 Paternal genomes are compacted during spermiogenesis and decompacted following fertilization.

96 ction for the ubiquitin-proteasome-system in spermiogenesis and define a novel, non-redundant physiol

97 histone H4 at residues K5, K8 and K12 during spermiogenesis and demonstrate corresponding defects in

98 ablish a direct role for pachytene piRNAs in spermiogenesis and embryo viability.

99 genic expression of Pacrg in testes restores spermiogenesis and fertility in qk(v) males.

100 To address this question, we characterized spermiogenesis and fertility in the Ift88(Tg737Rpw) mous

101 Expression starts early in spermiogenesis and finishes in the late spermatid phase.

102 ntial for the formation of centrioles during spermiogenesis and for the formation of centrosomes afte

103 collectively progressed through meiosis and spermiogenesis and generated epididymal sperm at approxi

104 in various chromatin-templated events during spermiogenesis and in the establishment of the sperm epi

105 s we found that H2AK119ub1 is present during spermiogenesis and into early embryonic development, hig

106 , spe-27 and spe-29) that specifically block spermiogenesis and lead to hermaphrodite-specific fertil

107 Due to its temporal appearance during spermiogenesis and location at the cortex of the fibrous

108 ng protein kinase 4 (HIPK4) is essential for spermiogenesis and male fertility in mice.

109 main (BRDT(DeltaBD1)) and observed disrupted spermiogenesis and male sterility.

110 e here that exposure to ATZ affects meiosis, spermiogenesis and reduces the spermatozoa number in the

111 lized to sperm flagella during all stages of spermiogenesis and spermatogenesis in male testes.

112 pecialization (ES) in testes, thus impairing spermiogenesis and spermiation.

113 ns, many of which express transiently during spermiogenesis and spermiation.

114 he mammalian sperm head and is important for spermiogenesis and stabilization of sperm structures.

115 tin accessibility and nucleosome eviction in spermiogenesis and that loss of histone acetylation lead

116 sor in the translation of TSOD-1 mRNA during spermiogenesis and thereby fine-tunes the level of Cu/Zn

117 des insights into intrinsic requirements for spermiogenesis, and (iii) establishes a model for studie

118 ses expressed in spermatids, are critical to spermiogenesis, and are required for male fertility in m

119 in mice disrupts piRNA biogenesis, prevents spermiogenesis, and results in male sterility.

120 g various mutants, protein expression during spermiogenesis, and RNAi knockdown of paternal Poc1, we

121 lencing continues from meiosis to the end of spermiogenesis, and we discuss implications for proposed

122 hat the temporal and spatial localization of spermiogenesis are critical determinants of male fertili

123 occurs, and block of Pygo2 function leads to spermiogenesis arrest and consequent infertility.

124 h azoospermia caused by a complete arrest of spermiogenesis at step 8 of round spermatids and failure

125 Near the end of spermiogenesis, basonuclin also accumulated in the acros

126 ng Cx43 overexpression due to the failure of spermiogenesis because no elongating/elongated spermatid

127 dues, a characteristic of chromatin in early spermiogenesis before eventual replacement of histones b

128 that Huwe1 is not essential for meiosis and spermiogenesis, but can result in accumulation of gammaH

129 tes tissues and is necessary for postmeiotic spermiogenesis, but loss of Blanks is not accompanied by

130 ect on calspermin expression but does impair spermiogenesis by disrupting the exchange of sperm basic

131 Hence, MIWI may control spermiogenesis by regulating the stability of these mRNA

132 During spermiogenesis, Caenorhabditis elegans spermatids activa

133 re completely infertile because of disrupted spermiogenesis characterized by asynchronous spermatid m

134 curred in elongating spermatids at a step in spermiogenesis coincident with chromatin displacement of

135 g of the spermatid genome early in mammalian spermiogenesis, coincident with the first detectable cha

136 Instead, paternal action during spermiogenesis exerts post-fertilization control to ensu

137 on with severe dysmyelination of the CNS and spermiogenesis failure.

138 cale helical twisting in the final stages of spermiogenesis, favoring its ultracompaction.

139 We conclude that Tdrd6 is essential for spermiogenesis, for CB structure, and for proper mature

140 However, the role of Cylicins during spermiogenesis has not yet been investigated.

141 ic AMP response element modulator-tau during spermiogenesis has recently been demonstrated, the trans

142 piRNAs) that are abundantly expressed during spermiogenesis in a MIWI-dependent fashion.

143 Spermiogenesis in driving males is characterised by abno

144 mk4-/- mice are infertile with impairment of spermiogenesis in late elongating spermatids.

145 se genes are essential for normal meiosis or spermiogenesis in mice, only one variant, observed in th

146 on frequency was observed to increase during spermiogenesis in postreplicative cell types when sperma

147 responsible for mRNA elimination during late spermiogenesis in preparation for spermatozoa production

148 Analysis of spermiogenesis in Pygo2 mutants reveals reduced expressi

149 importance of epigenetic remodelling during spermiogenesis in successful reproduction.

150 By examining spermiogenesis in the azh mutant mouse, characterized by

151 During spermiogenesis in the water fern, Marsilea vestita, basa

152 Spermatogenesis is blocked during late spermiogenesis in young adults.

153 our data demonstrate devastating defects on spermiogenesis, including incomplete sperm maturation an

154 tic sex chromatin (PMSC) persists throughout spermiogenesis into mature sperm and exhibits epigenetic

155 Spermiogenesis involves dramatic cell morphological chan

156 Spermiogenesis is a highly orchestrated developmental pr

157 Spermiogenesis is a radical process of differentiation w

158 Spermiogenesis is a rapid process that is activated by p

159 Mammalian spermiogenesis is a remarkable cellular transformation,

160 Spermiogenesis is aborted in double homozygotes, with an

161 Nuclear condensation during spermiogenesis is accomplished by replacing somatic hist

162 Spermiogenesis is characterized by a profound morphologi

163 phenotype, demonstrating that NHE8's role in spermiogenesis is germ cell-intrinsic.

164 rs, we find that the Lh-Lhcgrba induction of spermiogenesis is mediated through a cAMP/PKA signaling

165 on suggests that chromatin remodeling during spermiogenesis is not limited to nucleoproteins as part

166 Mammalian spermiogenesis is of considerable biological interest es

167 A key event in the process of spermiogenesis is the formation of the flagella, which e

168 on of postmeiotic spermatids to spermatozoa (spermiogenesis) is thought to be indirectly controlled b

169 esumably mediated by histone turnover during spermiogenesis, leads to dysregulation of chromatin acce

170 During mammalian spermiogenesis, major restructuring of chromatin takes p

171 genitor cells (CDKN2B), spermatid maturation/spermiogenesis (metalloproteinase and serine proteinase

172 As polysomes increase in early spermiogenesis, MIWI increases in polysome fractions.

173 the transit of developing spermatids during spermiogenesis must be segregated from the BTB to avoid

174 In the male, transcription ceases during spermiogenesis, necessitating the posttranscriptional re

175 Consequently, a limited degree of spermiogenesis occurs but this is accompanied by markedl

176 This rapid maturation, termed spermiogenesis, occurs without any new gene expression.

177 aired histone-to-protamine transition during spermiogenesis of any mosquito species.

178 n the formation of a motile apparatus during spermiogenesis of M. vestita.

179 have studied centrosome degeneration during spermiogenesis of mice.

180 of a sperm nucleus is required either during spermiogenesis or for subsequent sperm functions during

181 In nematodes, spermiogenesis, or sperm activation, involves a rapid ce

182 lop postmeiotic arrest at the first stage of spermiogenesis, phenotypically similar to Trf2(-/-) mice

183 mass nor a sperm pronucleus is required for spermiogenesis, proper egg activation, or the induction

184 gnaling pathway in females and inhibition of spermiogenesis-related functions in males.

185 SR1 plays an important role in regulation of spermiogenesis-related mRNA synthesis necessary for sper

186 suggested proteins that could be involved in spermiogenesis-related sumoylation events.

187 However, spermiogenesis remains defective, suggesting additional

188 Our data further prove that targeting late spermiogenesis represents an effective strategy for deve

189 Therefore, spermiogenesis represents an excellent in vivo model for

190 Mutant males exhibited defective spermiogenesis, resulting in oligoasthenoteratospermia.

191 undergo histone modification remodelling in spermiogenesis, resulting in reduced H3K27me3 in normal

192 we show that remodelling of histones during spermiogenesis results in the retention of methylated hi

193 During spermiogenesis, somatic-type chromatin is taken apart an

194 high homology to a multicopy gene, Y-linked spermiogenesis-specific transcript (Ssty), and together

195 During the process of spermiogenesis (sperm activation) in Caenorhabditis eleg

196 enesis (spermatid production by meiosis) and spermiogenesis (spermatid activation into actively motil

197 t, spermatogenesis (mitosis and meiosis) and spermiogenesis (spermatid maturation).

198 During spermiogenesis, spermatids undergo dramatic morphologica

199 Instead, the arrest of both meiosis and spermiogenesis suggests a control point that may serve t

200 tion, the expression pattern of Pacrg during spermiogenesis suggests that it plays a role in sperm di

201 During spermiogenesis, SUMO-1 localized in chromocenters of cer

202 emical model for how differential defects in spermiogenesis that result in the phenomenon of meiotic

203 During spermiogenesis (the maturation of spermatids into sperma

204 It has long been appreciated that spermiogenesis, the cellular transformation of sessile s

205 step 6, revealing a novel role for Boule in spermiogenesis, the differentiation of round spermatids

206 Spermiogenesis, the final phase of spermatogenesis when

207 Activation coincides with spermiogenesis, the final step in spermatogenesis, when

208 hromatin remodelling processes occurs during spermiogenesis, the post-meiotic phase of sperm developm

209 During spermiogenesis, the postmeiotic phase of mammalian sperm

210 s a major event that occurs during mammalian spermiogenesis, the process of spermatid maturation into

211 ere, we show that in Drosophila melanogaster spermiogenesis, the quantity of centrosomal proteins is

212 ic imaging of four organelles during primate spermiogenesis: the nucleus, the mitochondria, the acros

213 Drosophila melanogaster are remodeled during spermiogenesis through protein enrichment and ultrastruc

214 ealed that Cep104 and Cep97 cooperate during spermiogenesis to align spermatids and coordinate indivi

215 hromatin compartmentalization takes place in spermiogenesis to prepare the next generation of life.

216 tablishment of histone H4 acetylation during spermiogenesis to regulation of transcription co-repress

217 e of TSSK1 and 2, TSKS, was localized during spermiogenesis to the centrioles of post-meiotic spermat

218 During spermiogenesis, TPCL became associated with the acrosome

219 y role in spermatocyte development, inhibits spermiogenesis until the activation signal is received.

220 Expression of key regulators of spermiogenesis was unaffected in Boule(-/-) mice, sugges

221 transcripts encoding factors required during spermiogenesis were aberrant during preleptonema, and th

222 Antisense and sense both arrest spermiogenesis when blepharoplasts should appear, and ds

223 mice, spermatogenesis proceeded to step 8 of spermiogenesis when complete arrest occurred.

224 ding region B of CABYR are translated during spermiogenesis, where they localize, or which CABYR isof

225 r their timely translation at later times of spermiogenesis, which is critical to attain mature sperm

226 sists into the spermatid elongation phase of spermiogenesis, while Pros28.1B expression is prominent

227 riole degenerates during testicular stage of spermiogenesis, while the proximal centriole is lost dur

228 Arrest occurs in spermiogenesis, with complete absence of elongated and m

229 he regulation of spermatid activation during spermiogenesis, with the null phenotype being an absence

230 nduced in successive stages of spermato- and spermiogenesis, X-irradiated male mice were re-mated at