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1 ibly degraded by the highly conserved enzyme sphingosine-1-phosphate lyase.
2  and demonstrate that inhibiting the enzyme, sphingosine-1-phosphate lyase 1 (SPL), has neuroprotecti
3 he expression of sphingosine kinase 1 and 2, sphingosine-1-phosphate lyase 1, and sphingosine-1-phosp
4 otein kinase type I-beta regulatory subunit, sphingosine-1-phosphate lyase 1, centaurin beta 1, prote
5 hingosine-1-phosphate receptor-1 (S1PR1) and sphingosine-1-phosphate lyase-1 (SPL1) in splenocytes wa
6                 Conversely, FTY720 inhibited sphingosine-1-phosphate lyase activity in vitro.
7 eatment of mice with FTY720 inhibited tissue sphingosine-1-phosphate lyase activity within 12 h, wher
8                               The absence of sphingosine-1-phosphate lyase affects multiple stages th
9                              This identifies sphingosine-1-phosphate lyase as a dual modulator of sph
10                                              Sphingosine-1-phosphate lyase catalyzes the conversion o
11 osphate was stable in the presence of active sphingosine-1-phosphate lyase, demonstrating that the ly
12 iotropic effect, which is due to the loss of sphingosine-1-phosphate lyase, establishes sphingolipids
13           Recent studies have suggested that sphingosine-1-phosphate lyase expression affects animal
14 ese studies demonstrate that ELT-2 regulates sphingosine-1-phosphate lyase expression in vivo.
15 ian cell fate decisions, a recombinant human sphingosine-1-phosphate lyase fused to green fluorescent
16      We report the cloning of the Drosophila sphingosine-1-phosphate lyase gene (Sply) and demonstrat
17                 In this study, regulation of sphingosine-1-phosphate lyase gene expression was invest
18  Additionally, we demonstrate that the human sphingosine-1-phosphate lyase gene is regulated by a GAT
19 isruption in Dictyostelium discoideum of the sphingosine-1-phosphate lyase gene, which encodes the en
20 pound RBM10-8 can irreversibly inhibit human sphingosine-1-phosphate lyase (hS1PL) while behaving als
21                       To investigate whether sphingosine-1-phosphate lyase influences mammalian cell
22                                              Sphingosine-1-phosphate lyase is a widely expressed enzy
23 neumophila translocates the effector protein sphingosine-1 phosphate lyase (LpSpl) to target the host
24 ffects of FTY720 on immune function and that sphingosine-1-phosphate lyase may be a potential target
25                                        Thus, sphingosine-1-phosphate lyase overexpression in HEK293 c
26 er gene as well as an increase in endogenous sphingosine-1-phosphate lyase protein.
27 ial role, mechanisms affecting expression of sphingosine-1-phosphate lyase remain poorly understood.
28                                              Sphingosine 1-phosphate lyase (S1P lyase) irreversibly c
29                                              Sphingosine 1-phosphate lyase (S1PL) has been characteri
30 phingosine signaling pathways, we identified sphingosine-1-phosphate lyase (S1PL) as a drug target fo
31 iant, we describe the novel interaction with sphingosine 1-phosphate lyase (SGPL1)-a key enzyme for t
32 rome caused by loss-of-function mutations in sphingosine-1-phosphate lyase (SGPL1).
33 d (SL) mutant lacking the degradatory enzyme sphingosine 1-phosphate lyase (spl-).
34 ctions between FTY720, FTY720-phosphate, and sphingosine-1-phosphate lyase, the enzyme responsible fo