ライフサイエンスコーパス: spondyloarthritis

1 n IL-17 inhibitor, in non-radiographic axial spondyloarthritis.

2 ociated with systemic disease, such as axial spondyloarthritis.

3 e currently no diagnostic criteria for axial spondyloarthritis.

4 patients with active non-radiographic axial spondyloarthritis.

5 ty of upadacitinib in non-radiographic axial spondyloarthritis.

6 ts can improve the accuracy for diagnosis of spondyloarthritis.

7 hritides, including rheumatoid arthritis and spondyloarthritis.

8 ment, and patient global assessment in axial spondyloarthritis.

9 tis, but was ineffective in studies of axial spondyloarthritis.

10 n of upadacitinib for the treatment of axial spondyloarthritis.

11 e as targets for therapeutic intervention of spondyloarthritis.

12 anded in synovial tissues from patients with spondyloarthritis.

13 s with chronic back pain and suspected axial spondyloarthritis.

14 ) strongly predisposes to the development of spondyloarthritis.

15 causative in some cases of undifferentiated spondyloarthritis.

16 axis may be involved in the pathogenesis of spondyloarthritis.

17 , diagnosis and management of juvenile-onset spondyloarthritis.

18 th reduced radiographic progression of axial spondyloarthritis.

19 joints increases the diagnostic accuracy of spondyloarthritis.

20 es, including inflammatory bowel disease and spondyloarthritis.

21 d enthesitis-related arthritis (37 [67.3%]), spondyloarthritis (27 [49.1%]), and psoriatic arthritis

22 Since the original description of spondyloarthritis 50 years ago, results have demonstrate

23 tis (29% vs 80%, P < .001), undifferentiated spondyloarthritis (58% vs 93%, P < .001) and osteoarthri

24 viously shown efficacy in radiographic axial spondyloarthritis (also known as ankylosing spondylitis)

25 ith rest is the most common symptom of axial spondyloarthritis and affects more than 80% of patients.

26 tients and 109 controls (55 healthy, 54 with spondyloarthritis and connective tissue diseases) were s

27 state of ultrasound imaging with respect to spondyloarthritis and describes some of the limitations

28 With the use of HAART, the prevalence of spondyloarthritis and Diffuse Infiltrative Lymphocytosis

29 or HLA-B27; or 3) anterior uveitis with both spondyloarthritis and HLA-B27.

30 allele may contribute to the pathogenesis of spondyloarthritis and its unique phenotype through downs

31 e classification criteria for juvenile-onset spondyloarthritis and magnetic resonance imaging has all

32 of chronic inflammatory arthritis, including spondyloarthritis and rheumatoid arthritis.

33 ther forms of inflammatory arthritis such as spondyloarthritis and rheumatoid arthritis.

34 ndeed, some 'mixed-pattern' diseases such as spondyloarthritis and some forms of rheumatoid arthritis

35 nflammatory arthritis: rheumatoid arthritis, spondyloarthritis and systemic juvenile idiopathic arthr

36 ical features and overall diagnoses of axial spondyloarthritis, and consequently significantly affect

37 HLA-B27 transgenic) rats, an animal model of spondyloarthritis, and correlated with disease susceptib

38 sis in rheumatoid arthritis, osteoarthritis, spondyloarthritis, and gout.

39 tes in the blood and joints of patients with spondyloarthritis, and increased numbers of IL-17A(+)GM-

40 okine data in inflammatory bowel disease and spondyloarthritis, and microbiome:immune cell data from

41 ed with human leukocyte antigen B27-negative spondyloarthritis approximately 11 years prior, based on

42 ed with human leukocyte antigen B27-negative spondyloarthritis approximately 11 years prior, based on

43 l fluid-derived monocytes from patients with spondyloarthritis are enriched for IL7R(+) cells with a

44 f bony erosions in patients suspected having spondyloarthritis as compared to the routinely used T1 T

45 A), psoriatic arthritis (PsA) and peripheral spondyloarthritis, as well as of HLA-B27 and other MHC a

46 to the sacroiliac joint indicative of axial spondyloarthritis at MRI.

47 toms in patients with non-radiographic axial spondyloarthritis at weeks 16 and 52.

48 Axial spondyloarthritis (axSpA) comprises a spectrum of chroni

49 The axial spondyloarthritis (axSpA) disease concept has undergone

50 The term axial spondyloarthritis (axSpA) encompasses a heterogeneous gr

51 Diagnosis and management of axial spondyloarthritis (axSpA) has vastly improved over the p

52 Early-stage studies in axial spondyloarthritis (axSpA) identified disease-associated

53 Axial spondyloarthritis (axSpA) is a chronic inflammatory dise

54 Axial spondyloarthritis (axSpA) is an inflammatory disease of

55 ity of the broader category now called axial spondyloarthritis (AxSpA) is apparently the opposite.

56 ber of ankylosing spondylitis (AS) and axial spondyloarthritis (axSpA) Registries already in existenc

57 s (PsO), psoriatic arthritis (PsA), or axial spondyloarthritis (axSpA) who received ixekizumab (IXE)

58 o standardize imaging in patients with axial spondyloarthritis (axSpA), few studies have been publish

59 The worldwide epidemiology of axial spondyloarthritis (axSpA), psoriatic arthritis (PsA) and

60 frequently used for early diagnosis of axial spondyloarthritis (axSpA).

61 HLA-B27 positive subjects have less active spondyloarthritis compared to HLA-B27 negative subjects

62 signs and symptoms of non-radiographic axial spondyloarthritis compared with placebo at week 14.

63 Analyses of undifferentiated spondyloarthritis continue to suggest that chlamydiae, a

64 or rheumatoid arthritis, osteoarthritis, and spondyloarthritis, digital tomosynthesis detected bone a

65 ous rheumatic syndromes including arthritis, spondyloarthritis, DILS, vasculitides, connective tissue

66 Spondyloarthritis encompasses a group of common inflamma

67 of the interleukin-23/interleukin-17 axis in spondyloarthritis has important therapeutic implications

68 Juvenile-onset spondyloarthritis has variable clinical features that ma

69 tem associated with rheumatoid arthritis and spondyloarthritis have led to the gut-joint hypothesis,

70 rachomatis and C. pneumoniae in induction of spondyloarthritis have not been discussed.

71 eitis DESIGN: Machine learning of cases with spondyloarthritis/HLA-B27-associated anterior uveitis an

72 was to determine classification criteria for spondyloarthritis/HLA-B27-associated anterior uveitis DE

73 The criteria for spondyloarthritis/HLA-B27-associated anterior uveitis ha

74 Key criteria for spondyloarthritis/HLA-B27-associated anterior uveitis in

75 The misclassification rates for spondyloarthritis/HLA-B27-associated anterior uveitis we

76 f anterior uveitides, including 184 cases of spondyloarthritis/HLA-B27-associated anterior uveitis, w

77 5, a proton-sensing receptor associated with spondyloarthritis in genome-wide association studies and

78 Induction of inflammatory spondyloarthritis in mice increased IL-33 in BM plasma,

79 Older children with psJIA have features of spondyloarthritis, including relative male preponderance

80 ases including systemic lupus erythematosus, spondyloarthritis, inflammatory bowel disease and alopec

81 analysis of MRI scans from the Assessment of SpondyloArthritis International Society (ASAS) classific

82 diagnosis of SpA according to Assessment of SpondyloArthritis International Society (ASAS) criteria

83 commendations developed by the Assessment of SpondyloArthritis International Society (ASAS) that aim

84 th at least 20% improvement in Assessment of Spondyloarthritis International Society (ASAS20) respons

85 proportion of patients with an Assessment of SpondyloArthritis international Society 40 (ASAS40) resp

86 mposite outcome measure of the Assessment of SpondyloArthritis international Society 40 response at w

87 ificantly more patients had an Assessment of SpondyloArthritis international Society 40 response in t

88 The publication of the new Assessment of SpondyloArthritis International Society classification c

89 The new Assessment of SpondyloArthritis International Society classification c

90 th back pain who fulfilled the Assessment of SpondyloArthritis International Society criteria for SpA

91 mmatory changes fulfilling the Assessment of SpondyloArthritis international Society definition, and

92 In 2009, ASAS (Assessment in SpondyloArthritis international Society) association, pu

93 Primary endpoints were Assessment of SpondyloArthritis international Society-40 (ASAS40) resp

94 Axial spondyloarthritis is an immune-mediated inflammatory con

95 rthritis, as well as psoriatic arthritis and spondyloarthritis, is bringing new insights into the div

96 Patients with axial spondyloarthritis may also have inflammatory arthritis i

97 The pathogenesis of axial spondyloarthritis may involve genetic predisposition, gu

98 lled trials (RCTs) in non-radiographic axial spondyloarthritis (nr-axSpA) might be failing to identif

99 graphic sacroiliitis (non-radiographic axial spondyloarthritis), objective signs of inflammation (via

100 ral alternating anterior uveitis with either spondyloarthritis or a positive test result for HLA-B27;

101 h a history of the classic course and either spondyloarthritis or HLA-B27; or 3) anterior uveitis wit

102 MHC class I allele, HLA-B27, contributes to spondyloarthritis pathogenesis is unknown.

103 with other HLA class I could play a role in spondyloarthritis pathogenesis.

104 terleukin-17 axis plays an important role in spondyloarthritis pathogenesis.

105 rmacokinetics was investigated in a group of spondyloarthritis patients.

106 and may contribute to the development of the spondyloarthritis phenotype.

107 Nevertheless, rheumatoid arthritis and spondyloarthritis possibly result from the convergence o

108 Axial spondyloarthritis predominantly affects the sacroiliac j

109 matoid arthritis, psoriatic arthritis, axial spondyloarthritis, psoriasis, and inflammatory bowel dis

110 nflammatory arthritis (rheumatoid arthritis, spondyloarthritis, psoriatic arthritis), or psoriasis ta

111 luding 458 adults with rheumatoid arthritis, spondyloarthritis, psoriatic arthritis, ulcerative colit

112 ial of 411 adults with rheumatoid arthritis, spondyloarthritis, psoriatic arthritis, ulcerative colit

113 of individual inflammatory lesions in axial spondyloarthritis (SpA) has not been well established.

114 Spondyloarthritis (SpA) is a group of diseases with over

115 Spondyloarthritis (SpA) represents a family of inflammat

116 ss disease activity among 3435 patients with spondyloarthritis (SpA) who participated in a survey des

117 Spondyloarthritis (SpA), a type 3 immunity-mediated infl

118 e involvement are rheumatoid arthritis (RA), spondyloarthritis (SpA), and juvenile idiopathic arthrit

119 Gut inflammation is strongly associated with spondyloarthritis (SpA), as exemplified by the high prev

120 diseases like rheumatoid arthritis (RA) and spondyloarthritis (SpA), but the causal mechanisms linki

121 HLA-A3, which is not associated with spondyloarthritis (SpA), is also a ligand for KIR3DL2.

122 HLA-B*27 confers a strong risk of developing spondyloarthritis (SpA), which includes axial SpA with o

123 HLA-B27 is a major risk factor for spondyloarthritis (SpA), yet the underlying mechanisms r

124 ne-mediated inflammatory diseases, including spondyloarthritis (SpA).

125 and intestinal inflammation in experimental spondyloarthritis (SpA).

126 t paradigms of psoriatic arthritis (PsA) and spondyloarthritis (SpA).

127 ence for their potential pathogenic roles in spondyloarthritis (SpA).

128 the classification of preradiographic axial spondyloarthritis (SpA).

129 ases including rheumatoid arthritis (RA) and spondyloarthritis (SpA).

130 The SELECT-AXIS 2 non-radiographic axial spondyloarthritis study was a multicentre, randomised, d

131 -B27 test facilitates the diagnosis of axial spondyloarthritis such that patients from a community su

132 al examination in detecting many features of spondyloarthritis, such as synovitis and enthesitis.

133 at are more characteristic of other forms of spondyloarthritis than rheumatoid arthritis.

134 ities, medication usage, and side-effects in spondyloarthritis underscores the need for combining dat

135 patients with active non-radiographic axial spondyloarthritis were enrolled into the study, and 313

136 ion for patients with non-radiographic axial spondyloarthritis who had an inadequate response or were

137 ble adults had active non-radiographic axial spondyloarthritis, with objective signs of inflammation

138 e adults (aged >=18 years) with active axial spondyloarthritis without definite radiographic sacroili