ライフサイエンスコーパス: stable isotope labeling

1 e combined with experiments that incorporate stable isotope labeling.

2 movement of small molecules in plants using stable isotope labeling.

3 ransmission electron microscopies as well as stable isotope labeling.

4 ific modifications of a protein using in-gel stable isotope labeling.

5 investigated by PAGE, mass spectrometry, and stable isotope labeling.

6 on is achieved through the use of whole-cell stable isotope labeling.

7 brain regions using advanced proteomics and stable isotope labeling.

8 condary ion mass spectrometry (NanoSIMS) and stable isotope labeling.

9 n of lipids in monolayers and bilayers using stable isotope labeling.

10 m Lumbricus rubellus were investigated using stable isotope labeling.

11 se of a chronic-administration protocol with stable-isotope labeling.

12 We have used stable isotope labeling ((15)N) of E. coli RNA in conjun

13 (PSII) chlorophyll and proteins, a combined stable isotope labeling (15N)/mass spectrometry method w

14 ic detection of metabolites of interest with stable isotopes labeling allowed the discovery of new me

15 Using stable isotope labeling along with a two-step strategy f

16 We tested Census with stable-isotope labeling analyses as well as label-free a

17 nitor microbial mineralization using reverse stable isotope labeling analysis (RIL) of dissolved inor

18 to purify T-cell populations (<1 h) and then stable isotope labeling analysis conducted by mass spect

19 r of NAT, which was further confirmed by the stable isotope labeling analysis using deuterated acetat

20 Subsequent stable isotope labeling analysis using deuterated ethano

21 We used a combination of stable isotope labeling and arteriovenous difference mea

22 tome analysis of cardiomyocytes by combining stable isotope labeling and click chemistry with subsequ

23 monstrate whole-plant metabolic profiling by stable isotope labeling and combustion isotope-ratio mas

24 In vivo stable isotope labeling and computer-assisted metabolic

25 aves using stable isotope labeling (isobaric stable isotope labeling and isotope-coded affinity tags)

26 Here we used stable isotope labeling and isotopomer analysis to trace

27 y detection are typically conducted by using stable isotope labeling and label-free quantitation appr

28 g immobilization sites on a protein based on stable isotope labeling and MALDI-TOF mass spectrometry.

29 using a serine hydrolase probe, coupled with stable isotope labeling and mass spectrometry identified

30 Using metabolic stable isotope labeling and mass spectrometry, we demons

31 The combination of stable isotope labeling and molecular network generation

32 the phosphorylation of these sites by using stable isotope labeling and MS(2) analysis.

33 Using stable isotope labeling and proteomics, we identified a

34 The aim of the present study was to combine stable isotope labeling and tandem mass spectrometry for

35 Using stable isotope labeling and tandem mass spectrometry, we

36 hromatography-mass spectrometry coupled with stable isotope labeling and the accurate mass and time t

37 able of large-scale proteome profiling using stable isotope labeling and the determination of >5 prot

38 ough the one-carbon metabolic pathway, using stable-isotope labeling and detection of lysine methylat

39 d, conformational changes and dynamics using stable-isotope labeling and mass spectrometry (CDSiL-MS)

40 erformed on whole cells and cell walls using stable-isotope labeling and rotational-echo double-reson

41 analyze PDH-deficient parasites using rapid stable-isotope labeling and show that PDH does not appre

42 Using a novel combination of stable-isotope labeling and tandem mass spectrometry, we

43 Here, we combine MSI, stable isotope labeling, and a spatial variant of Isotop

44 asis of mass spectrometry (MS/MS and MS(3)), stable isotope labeling, and GC-MS analysis, we previous

45 high-resolution mass spectrometry, metabolic stable isotope labeling, and MS/MS-based isotopologue qu

46 resolution mass spectrometry (MS), metabolic stable isotope labeling, and PT-specific iodine-desulfur

47 rotein, molecular homology modeling, in vivo stable isotope labeling, and transient expression in pet

48 P rhesus monkeys in conjunction with in vivo stable-isotope-labeling, and dose-dependently reduced ne

49 A novel stable isotope labeling approach using (15)N and (18)O w

50 gestion exchange a convenient and affordable stable isotope labeling approach.

51 A novel stable-isotope labeling approach for identification of p

52 Using a metabolomic and stable-isotope labeling approach, combined with transcri

53 iplexed quantification methods, specifically stable isotope labeling approaches such as isobaric tags

54 by (13)C-MFA advanced methods for measuring stable-isotope labeling are needed.

55 This protocol is compatible with stable isotope labeling at the protein and peptide level

56 ed approaches-microarray gene expression and stable isotope labeling by amino acids in cell culture (

57 We developed a stable isotope labeling by amino acids in cell culture (

58 Through comparative stable isotope labeling by amino acids in cell culture (

59 dhesion molecules (CAMs), measured by pulsed stable isotope labeling by amino acids in cell culture (

60 iphosphate (ATP) affinity probe coupled with stable isotope labeling by amino acids in cell culture (

61 this RNA structure, we used a combination of stable isotope labeling by amino acids in cell culture (

62 Additionally, by comparing the stable isotope labeling by amino acids in cell culture (

63 quantification can be achieved by performing stable isotope labeling by amino acids in cell culture (

64 Using stable isotope labeling by amino acids in cell culture (

65 Super-stable isotope labeling by amino acids in cell culture (

66 By using stable isotope labeling by amino acids in cell culture (

67 We combined stable isotope labeling by amino acids in cell culture (

68 quantitation methods of biomolecules such as stable isotope labeling by amino acids in cell culture (

69 In this study, we adapted stable isotope labeling by amino acids in cell culture (

70 Using Stable Isotope Labeling by Amino acids in Cell culture (

71 ns were quantified by using the differential stable isotope labeling by amino acids in cell culture (

72 issue culture ((1)N/(1)N metabolic labeling, stable isotope labeling by amino acids in cell culture (

73 The method is based on stable isotope labeling by amino acids in cell culture (

74 Stable isotope labeling by amino acids in cell culture (

75 ass spectrometry combined with the method of stable isotope labeling by amino acids in cell culture (

76 As shown by stable isotope labeling by amino acids in cell culture (

77 omplex samples, such as those generated from Stable isotope labeling by amino acids in cell culture (

78 Quantitative stable isotope labeling by amino acids in cell culture (

79 onitoring (MRM)-based workflow together with stable isotope labeling by amino acids in cell culture (

80 A two-state stable isotope labeling by amino acids in cell culture (

81 d phosphoproteomics that incorporates triple stable isotope labeling by amino acids in cell culture (

82 titative proteomic data, including data from stable isotope labeling by amino acids in cell culture a

83 Stable isotope labeling by amino acids in cell culture a

84 Proteomics analysis was carried out using stable isotope labeling by amino acids in cell culture c

85 Stable isotope labeling by amino acids in cell culture e

86 Stable isotope labeling by amino acids in cell culture f

87 uantified in vivo by mass spectrometry using stable isotope labeling by amino acids in cell culture m

88 s paper, we describe systematic quantitative stable isotope labeling by amino acids in cell culture p

89 Quantitative proteomics based on stable isotope labeling by amino acids in cell culture s

90 To clarify these issues, we used dynamic stable isotope labeling by amino acids in cell culture t

91 of gene expression was revealed using pulsed stable isotope labeling by amino acids in cell culture t

92 We used a modified version of stable isotope labeling by amino acids in cell culture t

93 ed by modifying the widely used technique of stable isotope labeling by amino acids in cell culture t

94 We further performed stable isotope labeling by amino acids in cell culture t

95 tion, western blotting, immunoprecipitation, stable isotope labeling by amino acids in cell culture)

96 Proteins, extracted from a SILAC (stable isotope labeling by amino acids in cell culture)

97 proteins, we conducted a family-wide SILAC (stable isotope labeling by amino acids in cell culture)-

98 SILAC (stable isotope labeling by amino acids in cell culture)-

99 s was determined using a quantitative SILAC (stable isotope labeling by amino acids in cell culture)-

100 0 and 100 muM) in conjunction with an SILAC (stable isotope labeling by amino acids in cell culture)-

101 Combining this method with pulsed stable isotope labeling by amino acids in cell culture,

102 Stable isotope labeling by amino acids in cell culture,

103 ing mass spectrometry-based technologies and stable isotope labeling by amino acids in cell culture,

104 In a stable isotope labeling by amino acids in cell culture-b

105 In combination with the use of the stable isotope labeling by amino acids in cell culture-b

106 Using stable isotope labeling by amino acids in cell culture-b

107 n complexes and analyzed their components by stable isotope labeling by amino acids in cell culture-b

108 Using stable isotope labeling by amino acids in cell culture-m

109 Furthermore, using stable isotope labeling by amino acids in culture (SILAC

110 proteomic analyses of deletion strains using stable isotope labeling by amino acids in culture identi

111 er physiological light-dark conditions using stable isotope labeling by amino acids quantitative MS.

112 Stable isotope labeling by essential nutrients in cell c

113 This methodology of stable isotope labeling by essential nutrients in cell c

114 ons that occur during C. burnetii infection, stable-isotope labeling by amino acids in cell culture (

115 The goal of the present study was to use a stable-isotope labeling by amino acids in cell culture (

116 eukocyte life span estimates on the basis of stable isotope labeling can vary up to 10-fold among lab

117 ed magnetic beads, in conjunction with (18)O stable isotope labeling catalyzed by both trypsin and PN

118 ulfate depletion of the serum, an affordable stable isotope labeling chemistry for samples with a lar

119 The application of stable isotope labeling combined with SRM can overcome m

120 We utilized a recently developed method of stable-isotope labeling combined with cerebrospinal flui

121 investigate this disparity, we generated new stable isotope labeling data in healthy adult subjects u

122 ts were measured in vivo using a pulse-chase stable isotope labeling experiment.

123 heterogeneity, (3) and isotopic shifts from stable isotope labeling experiments are identified and a

124 The FFC algorithm is able to integrate stable isotope labeling experiments into the analysis an

125 Stable isotope labeling experiments show that, after MeJ

126 Stable isotope labeling experiments showed that ADT1 sup

127 d to further define this proposed synthesis, stable isotope labeling experiments were performed with

128 of the identified metabolites obtained from stable isotope labeling experiments.

129 Here, we describe the use of stable isotope-labeling experiments for studying metabol

130 ributions (MID) is of great significance for stable isotope-labeling experiments.

131 able of analyzing untargeted LC/MS data from stable isotope-labeling experiments.

132 Metabolic flux analysis based on stable-isotope labeling experiments and analysis of mass

133 BGC provided structural insights and guided stable-isotope labeling experiments, which led to the as

134 ease solubility and ionization, and utilizes stable isotope labeling for MS1 level identification of

135 h to differential metabolomics that involves stable isotope labeling for relative quantification as p

136 Mass spectrometry-based stable isotope labeling has become a key technology for

137 Stable isotope labeling has become a well-established su

138 n and post-translational modifications using stable isotope labeling has been achieved, but insights

139 In the present work, a stable isotope labeling HPLC-ESI(+)-MS/MS approach was e

140 investigated by a novel methodology based on stable isotope labeling HPLC-ESI(+)-MS/MS.

141 The stable isotope labeling HPLC-ESI-MS/MS approach describe

142 In the work presented here, a stable isotope labeling HPLC-ESI-MS/MS approach was empl

143 In contrast, stable isotope labeling in bacteria (SILIB) provided ful

144 Pulsed Stable Isotope Labeling in Cell culture (SILAC) approach

145 combines a photo-cross-linking strategy with stable isotope labeling in cell culture (SILAC)-based qu

146 Employing a stable isotope labeling in cell culture analysis in T47D

147 This stable isotope labeling in cell culture method enables t

148 show by blue-native gel electrophoresis and stable isotope labeling in cell culture proteomics that

149 used protein mass spectrometry with dynamic stable isotope labeling in cell culture to achieve a pro

150 g strategy, named GlyProSILC (Glycan Protein Stable Isotope Labeling in Cell Culture), that can label

151 by the AACT/SILAC (amino acid-coded tagging/stable isotope labeling in cell culture)-based quantitat

152 been greatly propelled by the development of stable isotope labeling in cell cultures (SILAC), a set

153 ificantly, PAF-C purifications combined with stable isotope labeling in cells (SILAC) quantitation fo

154 ghput quantitative studies using (16)O/(18)O stable isotope labeling in combination with the accurate

155 We conclude that stable isotope labeling in healthy humans is consistent

156 ere, we describe use of quantitative in vivo stable isotope labeling in mammals to accurately compare

157 strategy for brain proteomics called SILAM (Stable Isotope Labeling in Mammals).

158 Here, we use (13)C stable isotope labeling in mouse sperm isolated from the

159 issue in plant biology, we developed SILIP (stable isotope labeling in planta) using tomato plants (

160 We made use of stable isotope labeling in tissue culture (SILAC) to ide

161 Here, we use stable isotope labeling in vivo and proteomics to achiev

162 thod to measure carbohydrate composition and stable-isotope labeling in algal biomass using gas chrom

163 yrosine protein immunoprecipitation step and stable-isotope labeling, in a single experiment, we iden

164 Stable isotope labeling is central to NMR studies of nuc

165 nthesis/degradation ratio mass spectrometry, stable isotope labeling is employed to calculate a relat

166 A new method for proteolytic stable isotope labeling is introduced to provide quantit

167 Stable isotope labeling is the state of the art techniqu

168 A particular methodological challenge for stable isotope labeling is to ensure that the label is t

169 st proteomes of fully developed leaves using stable isotope labeling (isobaric stable isotope labelin

170 A stable isotope labeling kinetics experiment in NHPs was

171 product, sAPPalpha, in vivo in humans using stable isotope labeling kinetics, paired with immunoprec

172 report the translation of the human in vivo stable-isotope-labeling kinetics (SILK) method to a rhes

173 uthentic metabolite standards via the use of stable isotope labeling, liquid chromatography mass spec

174 Here, we describe an approach that combines stable isotope labeling, liquid chromatography- mass spe

175 uencing, global untargeted metabolomics, and stable isotope labeling mass spectrometry to identify me

176 Stable-isotope-labeling mass spectrometry involves the a

177 - and K-ras-derived DNA sequences by using a stable isotope labeling-mass spectrometry approach recen

178 To address this issue, a new stable isotope labeling method that targets tyrosine res

179 hod described here provides the first direct stable-isotope labeling method to definitely detect phos

180 Here we describe an improved stable-isotope labeling method using a phosphoprotein is

181 phoresis techniques, metabolic labeling, and stable isotope labeling methods to name only a few.

182 Stable isotope-labeling methods, coupled with novel tech

183 Stable isotope labeling-multiple reaction monitoring mas

184 Using stable isotope labeling of amino acids in a cell culture

185 e-enriched fractions, which were compared by stable isotope labeling of amino acids in cell culture (

186 is after SII stimulation using a strategy of stable isotope labeling of amino acids in cell culture (

187 s of pulmonary origin using the technique of stable isotope labeling of amino acids in cell culture (

188 en the development and implementation of the stable isotope labeling of amino acids in cell culture (

189 Combining iPOND with stable isotope labeling of amino acids in cell culture (

190 cycline-inducible RTA expression and applied stable isotope labeling of amino acids in cell culture (

191 abeling approaches such as isobaric tags and stable isotope labeling of amino acids in cell culture (

192 Using stable isotope labeling of amino acids in cell culture a

193 pled isotope-coded affinity tag, and coupled stable isotope labeling of amino acids in cell culture e

194 1 KO mice in combination with in vivo pulsed stable isotope labeling of amino acids in cell culture p

195 We used the stable isotope labeling of amino acids in cell culture p

196 roteins were screened by quantitative SILAC (stable isotope labeling of amino acids in cell culture)

197 Using a SILAC (stable isotope labeling of amino acids in cell culture)-

198 sequencing)-based transcriptomics and SILAC (stable isotope labeling of amino acids in cell culture)-

199 Using stable isotope labeling of amino acids in culture (SILAC

200 Stable isotope labeling of an intracellular chemical pre

201 measures three states simultaneously through stable isotope labeling of cells with amino acids in cel

202 Stable isotope labeling of CNS proteins can be utilized

203 elopment, we have established conditions for stable isotope labeling of cultured embryos under steady

204 o a solid support using hydrazide chemistry, stable isotope labeling of glycopeptides and the specifi

205 Surprisingly, results obtained with stable isotope labeling of mammals revealed that, in viv

206 Here, using metabolic stable isotope labeling of mice combined with mass spect

207 igh-resolution mass spectrometry of a double stable isotope labeling of P. nordicum enabled the speci

208 Stable isotope labeling of peptides is the basis for num

209 Differential (18)O/(16)O stable isotope labeling of peptides that relies on enzym

210 We report an enzymatic strategy for "stable isotope labeling of phosphonates in extract" (SIL

211 improved methods for chemical and metabolic stable isotope labeling of proteins and peptides.

212 tegy based on metabolic labeling of RNAs and stable isotope labeling of proteins for systematic profi

213 This protocol describes a strategy for stable isotope labeling of several widely used metal and

214 Stable isotope labeling of small-molecule metabolites (e

215 Differential stable isotope labeling of the ClpPRS complex with iTRAQ

216 and kinetic information without the need for stable isotope labeling of the molecules of interest.

217 noncanonical amino acid tagging (BONCAT) and stable-isotope labeling of amino acids in cell culture (

218 By coupling our methodology with stable-isotope labeling of amino acids in cell culture (

219 uantitative measurements can be performed by stable-isotope labeling of the peptides in the reductive

220 onalities needed to define fragments, manage stable isotope labeling, optimize collision energy and g

221 technologies with respect to the methods for stable isotope labeling, process automation and data pro

222 In this work an improved stable isotope labeling protocol for nucleic acids is in

223 Here, using heavy water (D(2)O) with Raman-stable isotope labeling (Raman-D(2)O), we evaluated the

224 ve proteomics, thanks to the availability of stable-isotope labeling reagents.

225 exchange between bound and free ligand or on stable isotope labeling, relying instead on a tert-butyl

226 Stable-isotope labeling reveals that even severely aggre

227 echniques, along with a judiciously designed stable isotope labeling scheme, to measure atomistic-res

228 Peptide quantitation based on stable isotope labeling showed that the surfactant induc

229 ids remodeled by the parasite cytoplasm, and stable isotope labeling shows some apicoplast lipids are

230 paper, we describe the complementary use of stable isotope labeling (SIL) and high-resolution mass s

231 In the present work, the solution-stable isotope labeling (SIL) combined with trapped ion

232 Stable isotope labeling (SIL) techniques have the potent

233 C), multiplexed ion beam imaging (MIBI), and stable isotope labeling (SIL), as well as approaches for

234 In addition, stable-isotope labeling simplified identification of the

235 In addition, a stable isotope-labeling step can be included to modify c

236 The use of stable isotope labeling strategies that are adaptable to

237 This dogma was recently challenged by stable isotope labeling studies with heavy water, which

238 a protein isoform analysis method utilizing stable isotope labeling tandem mass spectrometry (SILT M

239 Here, we used a stable isotope labeling technique ((18)O and (2)H) to de

240 Here, we applied a stable isotope-labeling technique in combination with ma

241 Using a stable isotope-labeling technique, we found that dexamet

242 We also employed a stable-isotope labeling technique to illuminate high-pri

243 Stable isotope labeling techniques for quantitative top-

244 We used two stable isotope-labeling techniques to identify kinetical

245 roughput in quantitative proteomics that use stable-isotope labeling techniques combined with high-re

246 Finally, we show using stable isotope labeling that in an embryonic mouse cell

247 Here we show, by stable-isotope labeling, that grasses produce tyrosine >

248 has been made thanks to the introduction of stable isotope labeling, the state-of-the-art technique

249 dimethylsulfonium moiety of SMM was shown by stable isotope labeling to be incorporated as a unit int

250 We applied stable isotope labeling to detect source-specific iron b

251 The approach was enhanced with stable isotope labeling to overcome ambiguities in deter

252 hod that relies on phosphatase treatment and stable-isotope labeling to determine absolute stoichiome

253 We further used stable-isotope labeling to trace the metabolic dynamics

254 titative protein profiling based on in vitro stable isotope labeling, two-dimensional polyacrylamide

255 with high sensitivity, we developed cysteine-stable isotope labeling using amino acids in cell cultur

256 d degreening were determined by differential stable-isotope labeling using formaldehyde.

257 we describe an integrated approach combining stable isotope labeling, various protein enrichment and

258 Using stable isotope labeling, we demonstrated that phosphocho

259 We utilized stable isotope labeling with amino acids (SILAC) in PTEC

260 Using stable isotope labeling with amino acids in cell culture

261 e analysis of the TIM23 interactome based on stable isotope labeling with amino acids in cell culture

262 hitis virus (IBV) N protein was mapped using stable isotope labeling with amino acids in cell culture

263 beling technique, NeuCode (neutron encoding) stable isotope labeling with amino acids in cell culture

264 ed for this study was generated using SILAC (Stable Isotope Labeling with Amino acids in Cell culture

265 tion mass spectrometry and quantification by Stable Isotope Labeling with Amino Acids in Cell Culture

266 elective surface biotinylation combined with stable isotope labeling with amino acids in cell culture

267 Using stable isotope labeling with amino acids in cell culture

268 teasome's composition in samples prepared by stable isotope labeling with amino acids in cell culture

269 In combination with stable isotope labeling with amino acids in cell culture

270 By dissecting the SlyA regulon using stable isotope labeling with amino acids in cell culture

271 ased on quantitative mass spectrometry using stable isotope labeling with amino acids in cell culture

272 escribes an integrated approach that couples stable isotope labeling with amino acids in cell culture

273 obtained on 462 proteins by using the SILAC (stable isotope labeling with amino acids in cell culture

274 By stable isotope labeling with amino acids in cell culture

275 Mass spectrometry-SILAC (stable isotope labeling with amino acids in cell culture

276 e used a newly established pipeline coupling stable isotope labeling with amino acids in cell culture

277 Here, we applied pulsed stable isotope labeling with amino acids in cell culture

278 Here, we used stable isotope labeling with amino acids in cell culture

279 ssisted affinity purification), coupled with stable isotope labeling with amino acids in cell culture

280 h for novel TBK1/IKKepsilon substrates using stable isotope labeling with amino acids in cell culture

281 Using stable isotope labeling with amino acids in cell culture

282 photyrosine profiling method with 'spike-in' stable isotope labeling with amino acids in cell culture

283 We report here that pulse-chase stable isotope labeling with amino acids in cell culture

284 n adherent and non-adherent conditions using stable isotope labeling with amino acids in cell culture

285 We coupled cell fractionation with stable isotope labeling with amino acids in cell culture

286 Using stable isotope labeling with amino acids in culture (SIL

287 proximity-labeled proteins were analyzed by stable isotope labeling with amino acids in culture (SIL

288 In this paper, we describe a stable isotope labeling with amino acids in culture-base

289 or absence of FTY720 were then identified by stable isotope labeling with amino cells in cell culture

290 Stable isotope labeling with d0- and d4-succinic anhydri

291 ll lifespan in humans in vivo.METHODSWe used stable isotope labeling with deuterated water to quantif

292 Stable isotope labeling with deuterium oxide, followed b

293 Stable isotope labeling with multiple reaction monitorin

294 Our approach in combining stable isotope labeling with NanoSIMS and TEM imaging ca

295 We couple stable isotope labeling with stimulated Raman scattering

296 Here, we combined stable isotope labeling with untargeted metabolomics to

297 s produced by this fungi, we combined a full stable isotopes labeling with the dereplication of tande

298 adecynoic acid (17-ODYA) in combination with stable-isotope labeling with amino acids in cell culture

299 We adapted stable-isotope labeling with amino acids in cell culture

300 ling measurements of metabolic function from stable isotope labeling within individual organelles in