ライフサイエンスコーパス: standard of care

1 6 LDN participants and 1948 nonparticipants (standard of care).

2 oratory-based testing without task shifting (standard of care).

3 p to five options, four active and the local standard of care).

4 lus paclitaxel should be considered as a new standard of care.

5 ults, and might be a suitable alternative to standard of care.

6 male circumcision services, and 15 received standard of care.

7 cinoma for whom there was no widely accepted standard of care.

8 d alcohol treatment referrals as part of the standard of care.

9 ely detected up to four years before current standard of care.

10 elevant to the COU compared with the current standard of care.

11 y identifies POEMS syndrome than the current standard of care.

12 nt of allergic reactions are considered dual standard of care.

13 se of peg-filgrastim relative to the current standard of care.

14 atients and in many cases represents the new standard of care.

15 The control groups continued local standard of care.

16 al, 3.54-16.93; P < 0.001) compared with the standard of care.

17 ib, and dexamethasone (CyBorD) is considered standard of care.

18 t serve as a useful addition to the existing standard of care.

19 ancer therapy or in combination with current standard of care.

20 ve shown promise but have not yet become the standard of care.

21 ly treated with taxane based chemotherapy as standard of care.

22 ET) for acute ischemic stroke is the current standard of care.

23 significant difference when compared to the standard of care.

24 a means of early diagnosis and no successful standard of care.

25 advanced tumors, chemoradiation is currently standard of care.

26 ents for whom blood cultures were ordered as standard of care.

27 agement with reduced acute care rates versus standard of care.

28 ulting in high mortality despite the current standard of care.

29 d survival but there is no commonly accepted standard of care.

30 ved with hydroxychloroquine in comparison to standard of care.

31 y invasive esophagectomy (MIE) compared with standard of care.

32 h potential for many settings beyond current standard-of-care.

33 laboratory testing based on clinic-specific standards of care.

34 ed to assess whether denosumab combined with standard-of-care adjuvant or neoadjuvant systemic therap

35 notecan and oxaliplatin (mFOLFIRINOX) is the standard-of-care adjuvant therapy, although data from se

36 Under the current standard of care, affected patients are subjected to a l

37 was to compare direct oral feeding (DOF) to standard of care after a minimally invasive esophagectom

38 ased chemotherapy should be considered a new standard of care after nephroureterectomy for this patie

39 r samples discordant between Clarity and the standard-of-care algorithm, the samples were tested with

40 standard-of-care infection prevention versus standard-of-care alone over a lifelong time horizon.

41 267 were randomly assigned (90 [34%] to standard of care and 177 [66%] to dabigatran) and includ

42 ported for 18 (20%) of 90 children receiving standard of care and 22 (13%) of 176 children receiving

43 eported in 22 (24%) of 90 children receiving standard of care and 38 (22%) of 176 children receiving

44 Similar proportions of children treated with standard of care and dabigatran met the composite effica

45 nts from the ATLAS trial, from both the oral standard-of-care and long-acting groups, must have compl

46 must demonstrate noninferiority to existing standards of care and measure longer-term outcomes.

47 Intensive Care Delirium Screening Checklist (standard of care) and Confusion Assessment Method for IC

48 clinical footprint, enabled them to improve standards of care, and enhanced opportunities for resear

49 eased antibacterial properties comparable to standard-of-care antibiotics both in vitro and in vivo,

50 hale as an adjunctive therapy to intravenous standard-of-care antibiotics for pneumonia caused by Gra

51 arasite MIF-blocking antibodies with current standard-of-care antibiotics might improve outcomes in s

52 All patients received standard-of-care antibiotics.

53 nt prostate cancer taken prior to starting a standard-of-care approved therapy.

54 pectively (intervention) or retrospectively (standard of care arm).

55 In the standard-of-care arm, CHWs visited women enrolled in pre

56 we did not have comparable data from the 7 "standard-of-care" (Arm C) communities.

57 en randomly allocated to transition from the standard of care (ART eligibility at CD4 counts of <350

58 with pericarditis, and it is now considered standard of care as second-line treatment for patients w

59 ID-19 convalescent plasma transfusion versus standard of care as treatment for severe and/or critical

60 line ART by 1 percentage point compared with standard of care, as reported in the STREAM trial.

61 udy, we found comparable DMD outcomes versus standard of care at facilities, a benefit for retention

62 glucocorticoid receptor (GR) are the current standard of care but drive adverse side effects such as

63 Both techniques are standard of care, but a direct randomised comparison is

64 omere protein (SP) gene mutations is current standard of care, but there are few data on long-term ou

65 ed with PT2385 alone and in combination with standard of care chemoradiotherapy.

66 OvC-PDE cultures were exposed to standard-of-care chemotherapeutics agents for 2 weeks, a

67 Efficacy of standard-of-care chemotherapeutics was assessed by measu

68 ate for targeted therapy in combination with standard of care chemotherapy agents in patients with ho

69 umab maintenance (1500 mg) every 4 weeks; or standard-of-care chemotherapy (gemcitabine plus cisplati

70 ), abemaciclib and trastuzumab (group B), or standard-of-care chemotherapy and trastuzumab (group C).

71 mbination with both temozolomide, a clinical standard-of-care chemotherapy for GBM, and everolimus, a

72 trastuzumab with or without fulvestrant with standard-of-care chemotherapy of physician's choice plus

73 ly improved progression-free survival versus standard-of-care chemotherapy plus trastuzumab while sho

74 that can be targeted to improve responses to standard-of-care chemotherapy regimens.

75 Standard-of-care chemotherapy was administered as specif

76 ced the toxicity and adverse consequences of standard-of-care chemotherapy.

77 Standard-of-care cine imaging was performed in short-axi

78 In standard-of-care clinics, participants received treatmen

79 n sensors, analyses the user's urine using a standard-of-care colorimetric assay that traces red-gree

80 bsolute increase of 9% to 93%) compared with standard-of-care communities (absolute increase of 2% to

81 b 25, 2018 (5896 in intervention and 4895 in standard-of-care communities).

82 of-study survey, 2625 residents (n=1304 from standard-of-care communities, n=1321 from intervention c

83 f drug versus placebo or drug versus current standard of care conditions.

84 strates positive outcomes when institutional standards of care consist of evidence-based supportive t

85 end the time to progression beyond that of a standard-of-care continuous therapy.

86 h for 5 days postoperative and tube feeding (standard of care, control group) following a MIE with in

87 toxicity findings from a randomised trial of standard-of-care conventionally fractionated or moderate

88 The standard-of-care cytoreductive chemotherapy depletes AML

89 Patients were randomised 1:2 (standard of care:dabigatran) and stratified by age (12 t

90 Standard of care diagnostic procedure for suspected skin

91 Current nAMD standard of care dictates frequent intravitreal (IVT) an

92 The standard-of-care drug ciprofloxacin suffers from severe

93 y that autologous gene therapies will become standard of care for a number of devastating diseases in

94 clinics would reduce mortality compared with standard of care for adults with advanced HIV disease.

95 BMDex should be considered a new standard of care for AL amyloidosis.

96 Endoscopically placed stents have become the standard of care for biliary drainage with the aim of im

97 Although mammography is the standard of care for breast cancer screening, dense brea

98 The standard of care for CNS prophylaxis for children with B

99 Radiotherapy plus cisplatin is the standard of care for eligible patients with HPV-positive

100 tic sequence, IVIg should be proposed as the standard of care for first-line treatment and rituximab-

101 zotetrazines (such as temozolomide, TMZ, the standard of care for glioblastoma) for use as synthetic

102 emic therapy should be considered as the new standard of care for HER2-positive and oestrogen recepto

103 Anti-GD2 immunotherapy is the current standard of care for high-risk neuroblastoma, but its ap

104 The standard of care for HIV-1 infection, highly active anti

105 The VRd triplet regimen remains the standard of care for induction therapy for patients with

106 Neoadjuvant radiation is standard of care for locally advanced rectal cancer.

107 Cisplatin is a standard of care for lung cancer, yet platinum therapy r

108 ve serotonin reuptake inhibitors (SSRIs) are standard of care for major depressive disorder (MDD) pha

109 Immunotherapy is standard of care for many malignancies, including non-sm

110 ombined with hypomethylating agents is a new standard of care for newly diagnosed patients with acute

111 Active surveillance remains the standard of care for patients at intermediate or high ri

112 cristine, and prednisone (R-CHOP) has become standard of care for patients with diffuse large B-cell

113 anial PFS and OS, and should be considered a standard of care for patients with good performance stat

114 stem cell transplantation (ASCT) remains the standard of care for patients with relapsed/refractory (

115 cal valve repair or replacement has been the standard of care for patients with valvular heart diseas

116 Chemoimmunotherapy is typically the standard of care for patients with Waldenstrom macroglob

117 in melanoma therapeutics has transformed the standard of care for patients, informed new approaches t

118 Transitional care services should become the standard of care for postdischarge management of patient

119 stem cell transplantation (HDT-ASCT) is the standard of care for relapsed or primary refractory (rel

120 Observation is the current standard of care for smoldering multiple myeloma.

121 e COVID-19 pandemic, primary PCI remains the standard of care for STEMI patients at PCI capable hospi

122 e adoption of this technology as part of the standard of care for the diagnosis of prostate cancer.

123 durvalumab plus platinum-etoposide as a new standard of care for the first-line treatment of ES-SCLC

124 Initially, the global burden of CVDs and the standard of care for the primary CVD categories, namely

125 arranted to test whether B/B improves on the standard of care for the treatment of acute AMR.

126 ubule inhibitors used as part of the current standard of care for TNBC.

127 hropoietin (EPO) and iron substitution are a standard of care for treatment of anemias associated wit

128 and economic impact of dupilumab compared to standard of care for uncontrolled moderate-to-severe ato

129 ctions in transplant recipients has been the standard of care for years, important challenges related

130 m ADT with dose-escalated PRT are reasonable standards of care for LPCa.

131 Current standards of care for medically supervised withdrawal in

132 mated and continue to exist, despite current standards of care for secondary prevention, including li

133 enrolled (492 received OLA and 495 received standard of care; four did not begin treatment).

134 patients with mutant ER MBC might respond to standard-of-care fulvestrant or other selective ER degra

135 yle leakage, which was more prevalent in the standard of care group (P = 0.032).

136 One on-treatment death occurred in the standard of care group (retroperitoneal bleeding, not co

137 l suppression compared with 162 (83%) in the standard-of-care group (difference 10.3%, 3.9-16.8; p=0.

138 ared with 39 (9.7%) of 402 (7.0-13.0) in the standard-of-care group (log-rank p=0.26).

139 to either the intervention group (n=195) or standard-of-care group (n=195).

140 OLA-guided therapy group and 16 (16%) in the standard-of-care group (p=0.90).

141 The reference group trial (RGT) was a standard-of-care group given basiliximab, tapered steroi

142 The standard-of-care group had 34 severe adverse events and

143 ntion group and 148 (76%) individuals in the standard-of-care group had the primary outcome of retent

144 -forward group and 12 (6%) of 205 men in the standard-of-care group received gonorrhoea and chlamydia

145 on group), or laboratory viral load testing (standard-of-care group).

146 in the OLA-guided therapy group than in the standard-of-care group: five (14%) of 35 compared with 1

147 atients treated with pembrolizumab than with standard of care had grade 3 or worse treatment-related

148 Advances in standards of care have extended the life expectancy of p

149 Antibiotic treatment is standard of care; however, dissemination of antimicrobia

150 atients with recurrent disease compared with standard of care imaging.

151 and can be challenging to distinguish using standard-of-care imaging.

152 Standard-of-care immunosuppression in the recipients in

153 do not respond to adjuvant therapy with the standard-of-care immunotherapy, bacille Calmette-Guerin

154 mmune checkpoint blockade (ICB) has become a standard of care in a subset of solid tumors.

155 ortezomib combination is emerging as a novel standard of care in AL amyloidosis.

156 ith potential to overcome the limitations of standard of care in children with venous thromboembolism

157 logous stem cell transplantation (ASCT) is a standard of care in eligible patients and results in imm

158 thymocyte globulin (ATG) has represented the standard of care in graft-versus-host disease (GVHD) pro

159 use of neurohormonal pharmacotherapies as a standard of care in HF.

160 n and dexamethasone (MDex) were considered a standard of care in light-chain (AL) amyloidosis.

161 tion ex vivo, have reached the clinic as the standard of care in limited indications and remain the s

162 They are collected as part of the standard of care in many diseases, particularly in pedia

163 HCQ + AZ has been used as the standard of care in more than 300,000 older adults with

164 s after surgery, thus establishing SN as the standard of care in OC.

165 DBS is a standard of care in Parkinson disease, essential tremor

166 oic acid) versus placebo (corn oil) daily to standard of care in patients aged 70 to 82 years with re

167 reatment strategies have been implemented as standard of care in patients receiving venetoclax to min

168 Platinum-based therapy is the standard of care in patients who have HER2-negative, adv

169 Endovascular therapy (EVT) is standard of care in patients with acute disabling ischem

170 oaches involving checkpoint blockade are now standard of care in patients with advanced RCC.

171 Doxorubicin is a standard of care in patients with advanced, inoperable s

172 on for heart failure (HHF) by 35%, on top of standard of care in patients with type 2 diabetes mellit

173 n is a World Health Organization-recommended standard of care in resource-limited settings, but the m

174 al chemotherapy (CRS & HIPEC) is the current standard of care in selected patients with limited resec

175 s may lead to unintended consequences as the standard of care in sepsis improves.

176 ing some of these technologies as the global standard of care in surgical practice.

177 Dabigatran was non-inferior to standard of care in terms of efficacy, with similar phar

178 Lenalidomide and dexamethasone has been a standard of care in transplant-ineligible patients with

179 ran dosed according to that algorithm versus standard of care in treating children with venous thromb

180 Rapalogs have become standard-of-care in patients with metastatic breast, kid

181 umab (in 33 [13%] patients) and fatigue with standard of care (in 43 [18%]).

182 at least a partial response after undergoing standard-of-care induction therapy followed by high-dose

183 al envelope cost-effectiveness compared with standard-of-care infection prevention strategies in the

184 ibacterial envelope (TYRX) use adjunctive to standard-of-care infection prevention versus standard-of

185 hed autism detection classifiers, trained on standard-of-care instrument scoresheets and tested on ra

186 When combined with the standard of care, ionized radiation, STAT3i SPNPs result

187 For persons who are exposed, the standard of care is observation and quarantine.

188 This standard of care is often temporarily successful but exh

189 no risk stratification systems exist and the standard of care is poorly defined.

190 Glioblastoma (GBM) resistance to the standard of care is prompting scientists to develop bett

191 lar lenses (IOLs) are available, the current standard of care is to offer treatment of astigmatism at

192 range, 8-17 years) who received placebo and standard of care lifestyle advice in 2 double-blind, ran

193 ased risk for non-major bleeding compared to standard of care, LMWH.

194 Standard of care (low-molecular-weight heparins, unfract

195 e recent LT population closer to the current standard of care (LT after the year 2000).

196 a-arrestin over G proteins, make methadone a standard-of-care maintenance medication for opioid addic

197 wer Vt and airway pressures than the current standard of care, may improve outcomes compared with con

198 an additional Candida species, undetected by standard-of-care methods.

199 with BCID-FP at 4 sites were compared to the standard-of-care microbiological and biochemical techniq

200 were investigated to determine the impact of standard-of-care modified Brooke (MB), limited-volume co

201 res who do not currently have an established standard-of-care neoadjuvant treatment.

202 ed that DOF following a MIE is comparable to standard of care (nil-by-mouth).

203 ment with pembrolizumab plus axitinib as the standard of care of advanced renal cell carcinoma.

204 3 months, after which both sites switched to standard of care offering dual testing for 3 months.

205 mised trials of intravenous alteplase versus standard of care or placebo in adults with stroke with u

206 administration once daily for 10 days) plus standard of care or to standard of care without macrolid

207 hacholine challenge test against the current standard of care over 20 years.

208 PPNs carrying a combination of siVEGF and standard of care Paclitaxel (PPN-Dual) at reduced doses

209 fitness and strength training paired with a standard of care placebo beverage.

210 of care treatments alone (control group), or standard of care plus SABR to all metastatic lesions (SA

211 Previous data suggest sirolimus may rival standard of care prednisone.

212 rated in patients for whom multiple previous standard-of-care preventive treatments had failed.

213 h tobramycin and colistin was implemented as standard of care prior to colorectal surgery.

214 B-cell lymphoma (DLBCL) are limited, with no standard of care; prognosis is poor, with 4- to 6-month

215 resistance and those who were randomised to standard of care received NNRTI-based first-line ART.

216 No standard of care regimen exists for the management of pa

217 ided as an adjunct to the currently accepted standard-of-care regimen (periodic prophylaxis and seria

218 ceived an uninterrupted first or second oral standard-of-care regimen for at least 6 months without v

219 approved by regulatory agencies, the current standard of care remains avoidance of allergenic foods a

220 The current standard of care-resection and chemoradiation-is limited

221 aining program following RYGB (RYGB + ET) or standard of care (RYGB).

222 nty-four additional cancers were detected by standard-of-care screening and 46 by neither approach.

223 iometry (DXA) is an internationally accepted standard-of-care screening tool used to assess fragility

224 was that daily addition of 1.8g n-3 PUFA to standard of care secondary prophylaxis in elderly patien

225 ividualized treatment with locally available standard of care should be considered for the underlying

226 Analysis of secondary outcomes (standard of care) showed no treatment differences for ac

227 The remaining 171 patients elected standard of care (SOC) (103), investigational therapy (2

228 Outcomes of standard of care (SOC) and early corticosteroid groups w

229 ion program delivered at 4 time points, with standard of care (SOC) education on improving readiness

230 vely confirmed diagnosis of VTE treated with standard of care (SOC) for >=3 months, or had completed

231 m were randomized 2:1 to receive PrEPmate or standard of care (SoC) for 36 weeks.

232 entification from positive blood cultures is standard of care (SOC) in many clinical microbiology lab

233 the cost-effectiveness of dalbavancin versus standard of care (SoC) in the treatment of ABSSSI in a c

234 lateral IVT, 1 eye was randomized to receive standard of care (SOC) lidocaine-based anesthesia and th

235 Patients randomized to standard of care (SOC) or evolocumab 420 mg monthly (evo

236 ed to receive GS immediately with concurrent standard of care (SoC) testing, or to receive SoC testin

237 transfusion strategy (TEG group; n = 49) or standard-of-care (SOC) group (n = 47).

238 atory-tract specimens previously analyzed by standard-of-care (SOC) NAATs.

239 report clinical outcomes with axi-cel in the standard-of-care (SOC) setting for the approved indicati

240 randomized in a 1:2 ratio between palliative standard-of-care (SOC) treatments (arm 1) and SOC plus S

241 t their primary care site or local hospital (standard of care [SOC]).

242 daily fixed-dose (Dactavira, n = 25) or the standard of care [SOF 400 mg/DCV 60 mg] (n = 25) daily f

243 However, the current standard of care soft tissue repair meshes for hernia re

244 This combination is being compared with standard-of-care sorafenib in a phase 3 trial.

245 lity to visualize the cervix compared to the standard-of-care speculum exam, (2) the feasibility and

246 ared dihydroartemisinin-piperaquine with the standard of care, sulfadoxine-pyrimethamine, showed dihy

247 e BD FACSPresto system with the conventional standard-of-care technologies for the measurement of abs

248 had higher sensitivity than did a historical standard-of-care test from the BD Veritor antigen test (

249 of age, and culture was performed as part of standard-of-care testing.

250 When compared with the current standard of care, the new pathway could save pound 1390

251 ul, could supplement the cancer cell-centric standard of care therapies in order to fully meet the th

252 ive malignancy with limited effectiveness of standard of care therapies including surgery, radiation,

253 s from both AML and CML can be refractory to standard-of-care therapies and persist in patients, dive

254 Despite the widespread use of standard-of-care therapies for CKD with T2D over the pas

255 PO1 is associated with resistance to several standard-of-care therapies, including chemotherapies and

256 r and likely contributes to poor response to standard-of-care therapies, suggesting that patients wit

257 ecline as compared to patients receiving the standard of care therapy.

258 gainst GBM and work in combination with both standard-of-care therapy and new precision medicine targ

259 ncer, and who had progressed after available standard-of-care therapy were recruited from seven hospi

260 gical intervention can be recommended as the standard of care; therefore, clinicians may choose not t

261 d although perioperative chemotherapy is the standard of care, this treatment strategy provides only

262 structions and hence merit a change in nasal standard-of-care, this study also demonstrates how relat

263 vere adverse events were vascular disorders (standard of care three [3%] of 90, dabigatran two [1%] o

264 ne ID (teleID) consults as an adjunct to the standard of care through the time period in which teleID

265 Elevating these techniques into standard-of-care tools will transform patient stratifica

266 After standard-of-care transjugular liver biopsy and HVPG pres

267 with severe COVID-19, adding azithromycin to standard of care treatment (which included hydroxychloro

268 ive radiotherapy should not be considered as standard of care treatment for retroperitoneal sarcoma.

269 daily for 10 days) because that was part of standard of care treatment in Brazil for patients with s

270 vIII sensitizes a fraction of GBM to current standard of care treatment through the upregulation of D

271 x, monthly) from 12 cAMR patients who failed standard of care treatment with intravenous immune globu

272 aused by Leishmania (Viannia) species during standard of care treatment with pentavalent antimonials.

273 nd systemic inflammation who received either standard-of-care treatment alone (10 patients) or combin

274 The standard-of-care treatment for EOC is platinum-based che

275 The standard-of-care treatment for localized disease has bee

276 Standard-of-care treatment for patients with newly diagn

277 cancer for which little change to first-line standard-of-care treatment has occurred within the last

278 ing of the stromal microenvironment, current standard-of-care treatment, and novel therapeutic target

279 andomized 2:1 to FAi or sham (injection plus standard of care) treatment.

280 patients (1:2) to receive either palliative standard of care treatments alone (control group), or st

281 mor activity compared to their corresponding standard of care treatments.

282 Ionizing radiation (IR) and chemotherapy are standard-of-care treatments for glioblastoma (GBM) patie

283 ave not benefited from or tolerated previous standard-of-care treatments.

284 1%] of 176), and gastrointestinal disorders (standard of care two [2%] of 90 and dabigatran five [3%]

285 nd ionizing radiation is part of the current standard-of-care used to slow tumor growth in both adult

286 Therefore, current standards of care usually involve combinations of multip

287 rbance of the microbiota in mice compared to standard-of-care vancomycin, thus paving the way for nov

288 mpicin resistance (Xpert) in sputum samples (standard of care) versus sputum Xpert combined with a la

289 Median exposure to standard of care was 85.0 days (IQR 80.0-90.0) and to da

290 of the antibacterial envelope compared with standard-of-care was $112 603/quality-adjusted life year

291 lasma from 14 cAMR patients treated with the standard of care were included as controls.

292 assay (OLA) to guide selection of ART or to standard of care, which did not include OLA testing.

293 We assessed whether adding azithromycin to standard of care, which included hydroxychloroquine, wou

294 ntrinsically co-registered hyperspectral and standard-of-care white light images, which allows image

295 Enrolled CLHIV received standard of care WHO-recommended first-line ART.

296 th concurrent chemotherapy should remain the standard of care, with the OS rate being among the highe

297 ily for 10 days) plus standard of care or to standard of care without macrolides.

298 While antimonial compounds are the standard of care worldwide, they are associated with sig

299 We aimed to compare Supraflex with the standard of care, Xience, an everolimus-eluting stent wi

300 s commonly become the basis for establishing standards of care, yet providers are often unaware of th