ライフサイエンスコーパス: sterile

1 , even though these hybrids were found to be sterile.

2 is dispensable for mitotic divisions-but are sterile.

3 devoid of functional PRX9 and PRX40 are male sterile.

4 sence, sperm does not form and male mice are sterile.

5 The eyemate(R)-IO sensor was suspended in a sterile 0.9% sodium chloride solution and placed in a wa

6 However, mtrm-null females are sterile [13], and sister chromatid cohesion is abolished

7 p21-activated kinase 4 (PAK4) and Mammalian sterile 20 kinase 4 (MST4) largely interconverted their

8 Mammalian sterile 20-like kinase 1 (MST1) is a key regulator of pa

9 dispensable for HCC formation when mammalian sterile 20-like kinase 1 and 2 (Mst1 and Mst2) were remo

10 sing of the incisional surgical wound with a sterile absorbent cover.

11 e of eggs into the environment ensuring only sterile adult males emerge.

12 nal tissues elicited by either infectious or sterile agents.

13 ns breathe in more than 10,000 liters of non-sterile air daily, allowing some pathogens access to alv

14 SARM1 (sterile alpha and HEAT/armadillo motif-containing protei

15 In recent years, sterile alpha and TIR motif containing 1 (SARM1) has eme

16 SARM1 (sterile alpha and TIR motif containing 1) is responsible

17 g enzymes (NADases) and the mammalian SARM1 (sterile alpha and TIR motif containing 1) NADase.

18 Sterile alpha and Toll/interleukin-1 receptor motif-cont

19 an intron of Samd14 (Samd14-Enh) encoding a sterile alpha motif (SAM) domain protein.

20 A conserved Sterile Alpha Motif (SAM) in the Polycomb Repressive Com

21 difference may be due to degradation of the sterile alpha motif and HD domain 1 (SAMHD1) host restri

22 Sterile alpha motif and HD domain-containing protein 1 (

23 Sterile alpha motif and histidine-aspartic acid domain-c

24 o identify de novo heterozygous mutations in sterile alpha motif domain-containing protein 9 (SAMD9,

25 This pentaloop is recognized by the sterile alpha motif domain-containing ZCCHC14 protein, w

26 We further show that SARM1 SAM (sterile alpha motif) domains form an octamer essential f

27 By deleting exon 13 (which encodes a sterile alpha motif) from the Trp73 gene, we selectively

28 Hundreds of sterile alpha-motif (SAM) domains have predicted structu

29 ches is considered incompatible as MAT kills sterile and 'wild' males indiscriminately.

30 salto-null male flies are sterile and exhibit complete spermatid individualization

31 SFiNX mutant flies are sterile and exhibit transposon derepression because piRN

32 ction of CD163 in steady-state as well as in sterile and infectious inflammation.

33 with knock-in of the human GRTH mutation are sterile and lack sperm with normal androgen and mating b

34 that can trigger iNKT cell activation under sterile and nonsterile conditions.

35 ntitumor immune responses and other forms of sterile and nonsterile inflammation.

36 e distinct clinical findings, testing of non-sterile and sterile site specimens, and enhanced enterov

37 varieties are for the most part seedless and sterile and therefore vegetatively propagated.

38 Since two of the genotypes concerned are sterile and very hard to generate, all the Northern blot

39 ut mutants of MPK1 were severely dwarfed and sterile, and homozygous mpk1 seeds from heterozygous par

40 The products were sterile, and the endotoxin levels were within acceptable

41 y analysis revealed that the CSF proteome in sterile animals was similar to that in infected animals

42 production was observed in seven events, and sterile anther-like organs in 10 events.

43 otein, an orthologue of Arabidopsis thaliana STERILE APETALA (SAP), that forms part of an SKP1/Cullin

44 ally rescued the fertility of this otherwise sterile ask1 allele in Landsberg erecta, thus providing

45 Thus, GE sterile avian surrogate hosts provide a viable platform

46 romycin resulted in faster FCT in those with sterile blood cultures and less relapses in culture-conf

47 t analysis of a single infecting genome in a sterile blood specimen are available and have recently b

48 -fixed, paraffin-embedded (FFPE) tissues and sterile body fluids with known diagnosis of IFD based on

49 We cultured blood and other normally sterile body fluids, reconfirmed and serotyped pneumococ

50 us (SA) infections (isolated from a normally sterile body site) in 8 counties in 5 states during 2016

51 solates for invasive MRSA (ie, from normally sterile body sites), 2005-2013.

52 short indeterminate branch with two proximal sterile bracts (glumes) followed by a variable number of

53 2019) reports that DAMP-induced sterile brain inflammation from stroke is associated wit

54 branches terminate in either a spikelet or a sterile bristle, and these structures appear to be paire

55 Sterile cerebrospinal fluid ascites in which no known in

56 Sterile cerebrospinal fluid ascites is a rare clinical e

57 She was ultimately found to have sterile cerebrospinal fluid ascites which was treated su

58 azid treatment regimen successfully attained sterile clearance and prevented disease reactivation.

59 er animals, especially away from controlled, sterile clinical settings where wounds urgently require

60 synthesis and automated synthesis modules, a sterile cold kit was recently introduced.

61 up's tracer activity was synthesized using a sterile cold kit.

62 tin receptor that can sense cell death under sterile conditions.

63 n 8 (MRP8, S100A8) and MRP14 (S100A9), under sterile conditions.

64 . epidermidis-infected catheters compared to sterile controls at day 1 postinfection.

65 rred in the T-ionto CL group; 1 eye (8%) had sterile corneal infiltrates, which did not affect the fi

66 about root exudation chemistry are based on sterile cultivation systems, which limits the discovery

67 To date, one man has achieved a sterile cure, with millions more hoping to avoid the pot

68 eflexes and behaviors, but can also regulate sterile cutaneous immunity in vivo.

69 Yet, the role of nociceptors in regulating sterile cutaneous inflammation remains unexplored.

70 in high mobility group protein 1 (HMGB1), a sterile danger signal molecule, and osteopontin (OPN), a

71 denosine triphosphate generation relative to sterile diorite suspensions.

72 vpr-1 null mutants are maternal effect sterile due to arrested gonadogenesis following embryo h

73 Bacterial spillage into a sterile environment following intestinal hollow-organ pe

74 terface between the intestinal lumen and the sterile environment of the lamina propria.

75 The fetal immune system develops in a rather sterile environment relative to the outside world and, t

76 ing spermatids, and Hipk4 knockout males are sterile, exhibiting phenotypes consistent with oligoasth

77 amine the use of genetically engineered (GE) sterile female layer chicken as surrogate hosts for the

78 ains or efficient sex separation methods but sterile females are ineffective control agents.

79 ne RAW 264.7 macrophages were incubated with sterile-filtered human saliva also in the presence of UD

80 , which in turn are possibly associated with sterile foliage allocated to Liaoningcladus.

81 he first 3 years, using outdoor mesocosms of sterile, freshly fallen volcanic ash from the Sakurajima

82 of interspecific hybridization between male sterile grain sorghum and johnsongrass and the ploidy of

83 proteins in the CSF of infected compared to sterile groups.

84 Finally, lethality caused by sterile hemolysis in mice required TLR4, TNFR1, and mito

85 The sterile hybrid male embryos were tested by injecting flu

86 Therefore, these sterile hybrid males may be suitable recipients for male

87 apy improved heart function through an acute sterile immune response characterized by the temporal an

88 Muscle damage elicits a sterile immune response that facilitates complete regene

89 it is the first vaccine capable of inducing sterile immunity against the current ASFV strain respons

90 and able to reduce morbidity and death when sterile immunity cannot be garnered quickly enough.

91 T cells were essential for the induction of sterile immunity during whole-organism vaccination.

92 At medium or higher doses (10(4) HAD(50)), sterile immunity is achieved.

93 exposures would induce protective long-lived sterile immunity targeting pre-erythrocytic stage parasi

94 c-primaquine/chloroquine is safe and induces sterile immunity to P. falciparum in some recipients, bu

95 c-primaquine/chloroquine is safe and induces sterile immunity to P. falciparum in some recipients, bu

96 us studies, CVac-chloroquine did not produce sterile immunity.

97 Isolates remained sterile in culture, producing neither conidia nor sexual

98 terus, Fallopian tubes and ovaries) might be sterile in healthy individuals or contain a low-biomass

99 l platform that allows IC-FPOP to occur in a sterile incubation system complete with a mobile stage f

100 restoration, and plants containing Y187 were sterile, indicating lack of fertility restoration.

101 is activated in macrophages by pathogen- or sterile-induced endomembrane damage.

102 e screening strategy induce a high degree of sterile infection-blocking protection against sporozoite

103 Three eyes (0.4%) developed sterile infiltrates, 1 (0.1%) had delayed epithelial hea

104 otential role of age-associated increases in sterile inflammation (inflammaging) and virus-induced dy

105 Sterile inflammation (SI) is an essential process in res

106 d differences, including pathways related to sterile inflammation and inflammasome regulation.

107 fXai but not fIIai inhibited sterile inflammation by reducing the expression of proin

108 We then created an in vitro model of sterile inflammation by treating healthy PBMCs with mito

109 have developed a detailed description of the sterile inflammation caused by overexposure to UVB irrad

110 r of, and therapeutic target for, minimizing sterile inflammation during human liver IRI.

111 l injury, shedding light on the mechanism of sterile inflammation during tissue injury and identifyin

112 differentiated between sepsis, infection and sterile inflammation from day 3 onward with an area unde

113 ata suggest that B cells contribute to early sterile inflammation in AKI via the production of leukoc

114 Sterile inflammation is a major clinical concern during

115 s the hypothesis that systemic stress-evoked sterile inflammation is initiated by the sympathetic ner

116 I/R) is a clinically relevant model of acute sterile inflammation leading to a reverberating, self-su

117 d during obesity, where immune cells promote sterile inflammation leading to insulin resistance.

118 s induce innate immune response, thus making sterile inflammation medically relevant.

119 rrest, and extravasation of neutrophils in a sterile inflammation model in the mouse footpad.

120 e the presentation of self-lipid antigens in sterile inflammation remain unclear.

121 lood-brain barrier (BBB), which may induce a sterile inflammation response.

122 venom induced pathophysiological response to sterile inflammation results into many harmful and delet

123 We propose that sterile inflammation should be considered an elemental f

124 etrotransposons is an important component of sterile inflammation that is a hallmark of ageing, and t

125 the role of oxidized lysoPL of stressEVs in sterile inflammation that promotes chronic diseases.

126 on-apoptotic forms of cell death can trigger sterile inflammation through the release of danger-assoc

127 In a model of sterile inflammation utilizing TLR4 ligation followed by

128 ), a hydrocarbon oil that mimics features of sterile inflammation when injected in vivo.

129 st, only very low levels were detected after sterile inflammation with silver nitrate despite levels

130 Sciatic nerve crush injury triggers sterile inflammation within the distal nerve and axotomi

131 mmon pathologic processes such as infection, sterile inflammation, and cancer both clinically and usi

132 ents that accumulate similarly in infection, sterile inflammation, and neoplastic tissue and then ext

133 CD123intBDCA-2+CD1a+ DC subset during acute sterile inflammation, and prompt a re-evaluation of prev

134 ress-evoked cytokine/chemokine responses, or sterile inflammation, can facilitate host survival and/o

135 led that type 2 immunity also contributes to sterile inflammation, cancer, and microbial infections.

136 , as a checkpoint regulator of IR stress and sterile inflammation, CEACAM1 may be considered as a den

137 ritic cells (DCs) were noted following acute sterile inflammation, including cell volume (4364.4 +/-

138 iew will introduce the reader to pathogen vs sterile inflammation, inflammatory receptor-ligand inter

139 ed in the cytosol, contributing to increased sterile inflammation, insulin resistance, and the develo

140 roup box 1 (HMGB1) clearly being involved in sterile inflammation, its role is controversial because

141 ischemic insult to the heart, which induces sterile inflammation, promoted, rather than limited, pro

142 6 significantly decreased hepatic markers of sterile inflammation, such as C-X-C motif chemokine 1, C

143 Using a mouse model of sterile inflammation, we demonstrated that signaling thr

144 The alarmin S100A8/A9 is implicated in sterile inflammation-induced bone resorption and has bee

145 ne response, but also form in and exacerbate sterile inflammation.

146 LPS-stimulated neutrophils as a model of non-sterile inflammation.

147 sm that controls iNKT cell activation during sterile inflammation.

148 nnate immune cells clear pathogens or induce sterile inflammation.

149 elayed lesion sterilization or non-resolving sterile inflammation.

150 y mediators may differentiate infection from sterile inflammation.

151 ion and accurately distinguish the foci from sterile inflammation.

152 be used as a therapeutic in the treatment of sterile inflammation.

153 for iNKT cell responses in various types of sterile inflammation.

154 tivates toll-like receptor 4 (TLR4)-mediated sterile inflammation.

155 especially in the areas of tissue injury and sterile inflammation.

156 rogressive muscle degeneration aggravated by sterile inflammation.

157 dent regulation of leukocyte postadhesion in sterile inflammation.

158 the differences between pathogen-induced and sterile inflammation.

159 d responses to external danger signals from "sterile" inflammation remain poorly understood.

160 merging roles for neutrophils in chronic and sterile inflammatory conditions, we sought to provide in

161 placed on the role of cGAS in the context of sterile inflammatory conditions.

162 nt in the context of numerous infectious and sterile inflammatory conditions.

163 t neutrophil IL-4Ralpha up-regulation during sterile inflammatory conditions.

164 in cancer was regulated by tumor antigen and sterile inflammatory cues.

165 block the recruitment of immune cells during sterile inflammatory diseases in humans.

166 itis model, representing 2 macrophage-driven sterile inflammatory diseases.

167 (PSA) can prevent various peripheral and CNS sterile inflammatory disorders.

168 The cobra and viper venoms-induced sterile inflammatory molecules (IL-6, HMGB1, HSP70, HSP9

169 alarmins may cause AKI in SCD, however, the sterile inflammatory process involved has hitherto not b

170 mbranes has been partially implicated in the sterile inflammatory process of term parturition.

171 owever, only recently have the importance of sterile inflammatory processes in this effect been revea

172 that platelet CLEC-2 influences the hepatic sterile inflammatory response and that this can be manip

173 Ischemic injury initiates a sterile inflammatory response that ultimately participat

174 ve been recognized as signaling mediators of sterile inflammatory responses after trauma and injury.

175 the presence of neutrophil infiltration into sterile injuries (in the absence of infections) suggests

176 Infectious and sterile injuries cause the release of PAMPs and DAMPs.

177 clusion is one of the most common and deadly sterile injuries in developed countries.

178 ir recruitment to damaged tissues upon acute sterile injuries is necessary for clearance of necrotic

179 ost organism or the organism is subjected to sterile injury.

180 s indispensable for tissue repair upon acute sterile injury.

181 emonstrate that the transgenic Bt cotton and sterile insect releases interacted synergistically to re

182 The sterile insect technique (SIT) and cue-lure (a synthetic

183 The sterile insect technique (SIT) has been successfully use

184 The sterile insect technique (SIT) has been used to successf

185 The radiation-based sterile insect technique (SIT) has successfully suppress

186 The sterile insect technique (SIT) is an environmentally saf

187 Central America it was eradicated using the Sterile Insect Technique (SIT).

188 lly eradicated from the United States by the sterile insect technique (SIT).

189 emale-to-male sex conversion, or to aid in a sterile insect technique that requires releasing only no

190 nsmission, including genetic versions of the sterile insect technique, artificial infection with Wolb

191 Here we show that combining incompatible and sterile insect techniques (IIT-SIT) enables near elimina

192 robial infections and mediating control over sterile insults.

193 host innate immune response to infection and sterile insults.

194 mmensal-containing intestinal tract from the sterile interior.

195 A recent increase in sterile intraocular inflammation after aflibercept (EYLE

196 is the largest study of aflibercept-related sterile intraocular inflammation, and is the only large

197 In a murine model of sterile kidney injury, reduced neutrophil infiltration,

198 endent programmed necroptosis in response to sterile ligands such as oxidized low-density lipoprotein

199 ), genetic (GMS) and chemically induced male sterile lines of Tx623 and Tx631 were pollinated with jo

200 ipuncture, blood was either aspirated into a sterile lithium heparin tube before blood culture bottle

201 ipuncture, blood was either aspirated into a sterile lithium-heparin tube before blood culture bottle

202 TLR4- and type I IFN-independent pathway of sterile liver injury in which hepatocytes are both the t

203 Pancreatitis starts with primarily sterile local inflammation that induces systemic inflamm

204 jury in more clinically-relevant E.coli (non-sterile LPS) murine ALI model.

205 In a control group (n = 11) we instilled sterile lysogeny broth endobronchially.

206 t barrier through the release of millions of sterile male and female flies in the border between Pana

207 However, housing with a sterile male early in life came at a cost to lifespan, w

208 offspring from the successful crossing were sterile male hybrids, thus an extreme form of Haldane's

209 to rear and release millions of competitive, sterile male Wolbachia-infected mosquitoes, and use of t

210 nd that those females previously housed with sterile males also showed enhanced late-life offspring p

211 rtantly, we demonstrate that pgSIT-generated sterile males are fit and competitive.

212 irradiation enabled mass production of adult sterile males for release.

213 sophila which consistently give rise to 100% sterile males.

214 in large-scale, low-cost production of male-sterile (ms) female lines necessary for hybrid wheat see

215 We characterized the male-sterile mutant empty anther1 (ean1) and identified EAN1

216 isolated and characterized a novel rice male sterile mutant, defective pollen wall3 (dpw3), which dis

217 Male-sterile mutants are largely due to an abnormal developme

218 Nuclear male-sterile mutants with non-conditional, recessive and stri

219 hylactic antibiotics to prevent infection of sterile necrosis is not recommended.

220 iated to higher mortality when compared with sterile necrotizing pancreatitis.

221 dark matter-in particular, that the decay of sterile neutrinos with a mass around 7 keV could match t

222 hough piRNA pathway protein mutants are male sterile, no biological function has been identified for

223 of the pair produces a seed and the other is sterile or male (staminate).

224 The lungs have been considered a sterile organ for decades because microbiological cultur

225 e used in aseptic food industry to guarantee sterile packages.

226 debridement may be required in patients with sterile pancreatic necrosis and persistent unwellness ma

227 sa in phosphate-buffered saline (PBS), while sterile PBS was used for controls.

228 of neutrophils and macrophages in a model of sterile peritonitis.

229 ar results were observed in a model of acute sterile peritonitis.

230 risk appears comparable to the risk using a sterile pharmaceutical based on social media data, curre

231 e this risk to a comparator procedure with a sterile pharmaceutical.

232 rol mice were intratracheally instilled with sterile phosphate-buffered saline.

233 dynamics in infiltrating macrophages during sterile physiological inflammation and tissue regenerati

234 hern Mexico included releases of billions of sterile pink bollworm moths from airplanes and planting

235 The F1 seeds obtained from BnCysP1 male-sterile plants and untransformed controls showed 1:1 (to

236 to distinguish S. epidermidis infection from sterile postoperative inflammation.

237 Live BCG, sterile PPD, and saline were bronchoscopically instilled

238 Sterile pre-FMT and post-FMT supernatants did not affect

239 d fetal loss in a mouse model of PAF-induced sterile preterm labor, and whether a small-molecule TLR4

240 In sterile preterm labor, the key regulators of inflammatio

241 The human oral cavity is sterile prior to birth, and we have limited knowledge of

242 le (VLP) known as Rv21, able to provide 100% sterile protection against a stringent sporozoite challe

243 VaccineHT(TM), enhanced vaccine efficacy and sterile protection following malaria challenge.

244 The resulting sterile protection strictly relied on the expression of

245 A highly effective vaccine that confers sterile protection to malaria is urgently needed.

246 Yet, sterile protection was achieved in the absence of this e

247 delayed patent parasitemia (P = .01) but not sterile protection, while 3/11 primaquine/chloroquine su

248 delayed patent parasitemia (p=0.01) but not sterile protection, while 3/11 primaquine/chloroquine su

249 protective CD8 T cell responses and ablated sterile protection.

250 Characterized by sterile pustules, erosions, and crusts, EPD is difficult

251 orested, agricultural, or fallow), with four sterile recipient soil treatments, differing in abiotic

252 Whereas ana3 mutants are male sterile, reflecting a requirement for Ana3 for centriole

253 he comprehensive metabolite profiling of non-sterile rhizosphere soil, which represents a technical a

254 od for untargeted metabolic profiling of non-sterile rhizosphere soil.

255 group) were orally administrated with either sterile saline or PEDV (the strain from Yunnan province)

256 oATP or sterile saline was administered via intraperitoneal inje

257 Sterile screws or screws colonized with bacteria were pl

258 All rats receiving sterile screws were culture-negative at euthanasia and d

259 in the tibia of 38 adult Wistar rats [n = 6 sterile screws; n = 6 S. epidermidis-colonized screws; n

260 hospital: chronic CF infection, sink drains, sterile site infections and asymptomatic carriage.

261 were defined as GAS isolated from a normally sterile site or from a wound in patients with necrotizin

262 linical findings, testing of non-sterile and sterile site specimens, and enhanced enterovirus surveil

263 infection (isolation of NTHi from a normally sterile site) between January 1, 2008, and December 31,

264 was defined as GBS isolated from a normally sterile site.

265 to colonizing organisms that gain access to sterile sites via disrupted epithelial barriers.

266 Isolates from sterile sites were serotyped by real-time polymerase cha

267 Here, using an acute sterile skeletal muscle injury model combined with irrad

268 omplex phenotype was associated with chronic sterile skin inflammation and could be partially rescued

269 ects of phosphate starvation, and a complex, sterile soil extract represented a more natural environm

270 oxylase/oxygenase (Rubisco) to show that the sterile spikelet assimilates carbon, which is translocat

271 The function of the sterile spikelet is unknown and that of the awn has not

272 Thus, the sterile spikelet, but not the awn, affects yield in the

273 Removal of sterile spikelets in sorghum significantly decreases see

274 Sterile stimuli can trigger inflammatory responses, and

275 ction and delay of preterm birth elicited by sterile stimuli.

276 ior to urine sampling from a new catheter or sterile straight catheterization, along with urine bacte

277 a clinically relevant condition of systemic sterile stress, cardiopulmonary bypass surgery, we confi

278 ity of EVs in vivo, we used a mouse model of sterile subcutaneous inflammation to determine the paylo

279 Sterile supernatants were created from pre-FMT and post-

280 GF mice were colonized using stools/sterile supernatants.

281 sthesia followed by administration of 4 g of sterile talc slurry.

282 findings shed new light on GM-CSF biology in sterile tissue inflammation and identify several potenti

283 Sterile tissue injury due to trauma also increases leuko

284 ses leukocyte demand; however, the effect of sterile tissue injury on hematopoiesis is not well descr

285 study how biofilm might be transferred into sterile tissue/implant materials during injections for j

286 ter-jet on high and (4) low, and compared to sterile, untreated and Chlorhexidine-treated controls.

287 ic rats received eye drops containing NTX in sterile Vigamox(R).

288 compared to fresh frozen plasma (28.6%) and sterile water (20.0%) (P = 0.01).

289 f AGS-v with adjuvant (Montanide ISA 51), or sterile water as placebo.

290 Distillery fermentations are non-sterile, which allow bacterial communities to flourish,

291 acn1 double mutant is delayed in growth and sterile, which is associated with hyperaccumulation of c

292 t flies are viable, female-fertile, but male-sterile, which is due to defects in meiosis and spermati

293 GRTH-KI mice are sterile with reduced testis size, lack sperm with sperma

294 We report that Tug1-knockout male mice are sterile with underlying defects including a low number o

295 Pistillate florets of drl1 ears are sterile with unfused carpels that fail to enclose an exp

296 cmb mutants are male sterile, with actin cones that fail to move in a synchro

297 re transmitted undiluted in this system, but sterile workers produced with sperm from a sexually-repr

298 caste systems, with reproductive queens and sterile workers, which often play distinct roles in the

299 between fertile queens and the more or less sterile workers.

300 playing important roles in other settings as sterile wound healing, autoimmunity, cancer, and homeost