ライフサイエンスコーパス: stiffness

1 scores indicating worse pain, function, and stiffness).

2 hanical work on the fiber, regardless of its stiffness.

3 s, which is known to be related to substrate stiffness.

4 lterations in angiotensin II-mediated aortic stiffness.

5 fness 100 times larger than the known static stiffness.

6 wth rate in response to an increasing matrix stiffness.

7 fiber alignment, a marker of increasing ECM stiffness.

8 roved feedback correction and an increase in stiffness.

9 otein titin, the main determinant of myocyte stiffness.

10 result of two properties: EGL thickness and stiffness.

11 PPPCD was a significantly increased corneal stiffness.

12 monary vascular resistance and less arterial stiffness.

13 d mutagenesis in titin that alter the I-band stiffness.

14 exhibit nearly a two-fold decrease in axial stiffness.

15 tility, leading to reduced connective-tissue stiffness.

16 migration, amoeboid transition, and cellular stiffness.

17 rt agarose gels tuned to mimic native tissue stiffness.

18 ons, with their ratio modulated by substrate stiffness.

19 the surrounding tissue leading to changes in stiffness.

20 currence in older women with greater carotid stiffness.

21 driven by a reward-dependent increase in arm stiffness.

22 st subject to arrive at a mutually preferred stiffness.

23 idential surrounding greenspace and arterial stiffness.

24 endent option to treat spasticity and muscle stiffness.

25 nsidered in cases of exercise-induced muscle stiffness.

26 istinct phenotypes on substrata of different stiffnesses.

27 cle reveal an I-band spring with an undamped stiffness 100 times larger than the known static stiffne

28 burst area after adjusting for carotid beta-stiffness (-116.1 +/- 135.0 vs. -185.9 +/- 148.2 a.u. bu

29 ulse-wave velocity (cfPWV) measured arterial stiffness 2, 12, 24, and 42 weeks post-ART initiation.

30 trates with alternating regions of different stiffness (200 and 800 kPa).

31 In addition, VSMC stiffness (-46.6%) and ex vivo aortic ring contraction f

32 rospun fibrin microfiber sheets of different stiffnesses (50.0 +/- 11.2 kPa and 90.0 +/- 16.4 kPa) to

33 e used polyacrylamide (PA) gels with varying stiffness (6.5-92.5 kPa) as the substrate to construct a

34 olids, allows for simultaneous high specific stiffness (8.4 MN.m/kg) and energy absorption (4.4 kJ/kg

35 at extracellular matrix (ECM) elasticity, or stiffness, affects fundamental cellular processes, inclu

36 This results in the hydrogel layers of lower stiffness allowing either the mixing of the loads occupy

37 whether physical properties such as cellular stiffness also change upon loss of Cltc, similar to what

38 'under the skin' and measure how exoskeleton stiffness alters soleus muscle contractile dynamics and

39 y is that it is also driven by increased arm stiffness, an energy-consuming process that enhances lim

40 through cell-driven changes in extracellular stiffness and "outside-in" integrin signaling.

41 There was a negative correlation between LA stiffness and %predicted VO2 (r = -0.50, p = 0.04).

42 metastatic colorectal cancer increase tissue stiffness and angiogenesis.

43 There was no association between liver stiffness and any patient variable or MRI scanner factor

44 epicarp is not normally consumed due to its stiffness and astringent taste, and in manufacture of pr

45 proteins in vascular tissue affect vascular stiffness and calcification, which is associated with ca

46 different ECM proteins and regulate cellular stiffness and cytoskeletal orientation, thus impacting t

47 llular matrix proteins and regulate cellular stiffness and cytoskeletal orientation, thus impacting t

48 the absence of fibrosis or steatosis, liver stiffness and fat fraction did not show any relationship

49 n adapt their nanomechanical properties (ie, stiffness and height) to changes in the environment.

50 etric wall fracture, accomplishing both high stiffness and high energy absorption.

51 tained more proteins associated with reduced stiffness and higher tissue remodeling, as well as a dua

52 that provide swelling pressures, compressive stiffness and hydration to the tissue.

53 lled by the interparticle adhesion, but that stiffness and inelasticity of the grains also play a sig

54 tive treatment with DAA attenuated the liver stiffness and inflammation but did not improve VD levels

55 ness a universal behavior of the local chain stiffness and invariability of the bead length.

56 e interfacial properties such as interfacial stiffness and mobility, the former of which demonstrates

57 There are sex differences in arterial stiffness and neural control of blood pressure (BP) amon

58 le anisotropy, as well as increased material stiffness and plastic deformation.

59 ential for the augmentation of intracellular stiffness and regulation of cytoskeletal remodeling; and

60 of nanoparticle aggregates, and CDN-dictated stiffness and self-healing functions of hydrogels.

61 or activation of TTL is sufficient to lower stiffness and speed relaxation in cardiomyocytes from pa

62 eal dramatic regional variations in material stiffness and strain energy, which reflect local changes

63 sculogenesis by using hydrogels with tunable stiffness and stress relaxation.

64 elation between the fluctuations in cellular stiffness and that of intracellular stresses.

65 tates, we also demonstrate 2D reprogrammable stiffness and three-dimensional (3D) magnetic clutching

66 The stiffness and tunability of the I-band spring implicate

67 n actin, apparently increasing thin-filament stiffness and ultimately depressing contractile force an

68 amelioration in vascular function, arterial stiffness and vascular remodelling by improving central

69 Vascular function, arterial stiffness and vascular remodelling were evaluated before

70 lony formations by the combined stressors of stiffness and X-ray exposure.

71 Since both stiffness and X-ray radiation are DNA-damaging stressors

72 Purpose To determine normal liver stiffness, and associated normal ranges for children, as

73 Real-time measurement of cell adhesion, stiffness, and imaging were performed using atomic force

74 omosome hypocondensation, loss of centromere stiffness, and mislocalization of the chromosome passeng

75 ed in the cortical bone structure, rigidity, stiffness, and modulus of the HGPS G608G mouse model may

76 ring, while preserving mechanical stability, stiffness, and nonlinearity.

77 aying short stature, brachydactyly and joint stiffness, and ocular features including microspherophak

78 oteins are widely used to assess the role of stiffness, and results from such experiments are often a

79 mechanoelectrical transduction, hair bundle stiffness, and spontaneous bundle oscillation can occur

80 ction forces (vGRFs), stride kinematics, leg stiffness, and symmetry.

81 contractility, myocyte hypertrophy, arterial stiffness, and systemic resistance.

82 cation stress significantly reduced skeletal stiffness, and warming weakened it, potentially curtaili

83 s demonstrated that ZNF217 mediates a matrix stiffness- and collagen density-induced increase in Akt

84 Brachydactyly and joint stiffness appear less commonly in patients with WMS4 cau

85 Vascular function and arterial stiffness are important markers of cardiovascular health

86 , and their transparency, degradability, and stiffness are modulated as a function of number of PEG a

87 We aimed to evaluate LA function and stiffness associations with ECV, tricuspid regurgitation

88 3D-MRE, the damping ratio at 40 Hz and shear stiffness at 60 Hz best correlated with NASH.

89 eads detected a decrease of the cross-bridge stiffness at negative forces attributed to the buckling

90 rods are used to evaluate the local loss of stiffness at the locations of nicks and Holliday junctio

91 cted p < 0.0125) and higher follow-up aortic stiffness (B = -1.12, 95% CI -1.95, -0.29, Bonferroni-co

92 ions of uniformity in cell contractility and stiffness break down in postconfluence confined multicel

93 nd find that softer cells show an increasing stiffness but decreasing plasticity with higher forces,

94 lational modifications do affect microtubule stiffness but do not affect the number of protofilaments

95 nd fluorescence exchange was related to cell stiffness by atomic force microscopy.

96 ve effect within poly-Ps that enhances their stiffness by diminishing the stability of the cis confor

97 nspace exposure may protect against arterial stiffness by promoting physical activity, fostering soci

98 To test whether three-dimensional (3D) niche stiffness can alter SC behavior or fate, we embedded iso

99 Joint pain, swelling, and stiffness can endure for months to years after CHIKV inf

100 ther, these data suggest that changes in ECM stiffness can modulate the morphology, cytoskeletal orga

101 Increased matrix stiffness can promote cancer progression, and two-dimens

102 -shaped RSPs with a manufacturer-recommended stiffness category based on body mass and activity level

103 P models (p < 0.05), but was not affected by stiffness category, actual stiffness (kN/m), or height (

104 However, at higher stiffness, cells form shorter and more transient invadop

105 ving arterial endothelial function, arterial stiffness, central and systemic blood pressure (BP), ins

106 These architectures provide a continuous stiffness change of the underlying substrate post engage

107 the integrins on a cell and quantified cell stiffness, chromatin deformation, and DHFR (dihydrofolat

108 odes and inhibiting myosin II decreases cell stiffness, chromatin deformation, and gene upregulation.

109 stress fibers abolishes differences in cell stiffness, chromatin stretching, and DHFR gene upregulat

110 ultimate goal is to create high strength and stiffness commodity materials capable of repair without

111 Recent studies have quantified how the stiffness component of mechanical impedance varies durin

112 rly 30% greater in LVH than in controls (LVH stiffness constant, 0.053+/-0.027 versus controls, 0.042

113 Left atrial (LA) dysfunction and stiffness contribute to the development of diastolic hea

114 Aging increases aortic stiffness, contributing to cardiovascular risk even in h

115 can be achieved by minimising position sway (stiffness control: SC) or minimising force error (force

116 To characterize stiffness, conventional techniques use cell contact or i

117 Tissue stiffness correlated variably with cell number density,

118 arterial remodelling improved, and arterial stiffness decreased in all the arteries, suggesting modi

119 CD4(+) T cells exhibit much more profound stiffness dependency than CD8(+) T cells.

120 pMLC) immunofluorescence, moreover, revealed stiffness-dependent differences in the subcellular distr

121 regulatory processes that ultimately govern stiffness-dependent NSC fate commitment are not fully un

122 Additionally, increased footwear bending stiffness did not affect muscle activity (all seven meas

123 Hence, footwear bending stiffness does not appear to alter the volume of aerobic

124 t to be associated with cardiac fibrosis and stiffness due to alteration of myocardial extracellular

125 ase their growth rate with increasing matrix stiffness, even though the forces needed to maintain a c

126 preferential CPP into cells with lower cell stiffness, expected from equilibration of pressure towar

127 at enables self-healing and a reprogrammable stiffness for dynamic tuning of mechanical metamaterials

128 t all measured EVs have a strikingly similar stiffness, further reinforcing the hypothesis that their

129 to cytoskeletal remodeling and intracellular stiffness generation to modulate FBGC formation.

130 we identify an anteriorly biased mesodermal stiffness gradient along which cells move to shape the e

131 The stiffness gradient corresponds to a Wnt5a-dependent doma

132 Tumour-specific suprabasal stiffness gradients are generated as oncogenic lesions p

133 are suggested to contribute to the observed stiffness gradients.

134 52 patients had mean liver stiffness >= 15 kPa.

135 rhosis (defined histologically or when liver stiffness >=12 kPa) treated with DAAs.

136 nsity fat fraction (MRI-PDFF) >=8% and liver stiffness >=2.5 kPa by magnetic resonance elastography (

137 In particular, LV stiffness has not been compared between LF vs NF.

138 rstanding and accounting for these biases in stiffness has the potential to enable estimation of tota

139 follow gradients of extracellular mechanical stiffness, has been proposed as a mechanism driving dire

140 elope to bending, quantified by the flexural stiffness, helps determine the microtubule-dependent nuc

141 al adhesion behavior is locally regulated by stiffness; however, how cells globally adapt, detect, an

142 Targeting tissue stiffness improves the outcome of anti-angiogenic therap

143 te elevated left ventricular (LV) myocardial stiffness in comparison with healthy controls as a key m

144 echanical properties, including low cellular stiffness in contrast to differentiated cells, which are

145 ibrosis Score, Fibrosis-4 (FIB-4), and liver stiffness in F4).

146 Here, we found an age-associated increase in stiffness in human lenses that was directly correlated w

147 min K supplementation might improve arterial stiffness in patients in CKD, we conducted a parallel-gr

148 LV myocardial stiffness in patients with LVH and elevated biomarkers (

149 spatiotemporal changes of spinal cord tissue stiffness in regenerating adult zebrafish and provides t

150 uate and quantify the diaphragm function and stiffness in relevant patients.

151 m of the fluid and solid parts, by examining stiffness in the peritumoural tissue with MR elastograph

152 ship was discovered between impact force and stiffness in the porous bone mimics, which indicates a r

153 keratocytes on flexible substrata of varying stiffness in the presence (or absence) of TGF-beta1.

154 hononic excitations and their characteristic stiffness, in an apparently inseparable manner.

155 As exoskeleton stiffness increased, the soleus muscle operated at longe

156 we find that during maturation, DC cortical stiffness increases via a process that involves actin po

157 Aortic stiffness increases with age and is a robust predictor o

158 rorheological measurements show that network stiffness increases with cation concentration.

159 An LV stiffness index of > 0.11 ml(-1) was independently assoc

160 Echocardiographic LV stiffness index was measured by a method previously vali

161 Compared to NF, LF severe AS had higher LV stiffness indices (>0.11 ml(-1) OR 3.067, 95% CI 1.825-5

162 Aortic stiffness is closely linked with cardiovascular diseases

163 and new data that confirm that cross-bridge stiffness is nearly linear in the muscle filament lattic

164 ch humans can voluntarily regulate leg joint stiffness is not yet known.

165 t after a collision with increasing membrane stiffness is observed.

166 Aortic stiffness is reduced through supervised training program

167 Liver stiffness is related to the degree of hepatic fibrosis w

168 ionship between oxidative stress and cardiac stiffness is thought to involve modifications to the gia

169 s not affected by stiffness category, actual stiffness (kN/m), or height (p = 0.72, p = 0.37, and p =

170 High ECM stiffness leads to ligand-independent phosphorylation of

171 ropose that increased tumor microenvironment stiffness leads to stromal cell-mediated TGF-beta family

172 Simulation results show that nuclear stiffness limits the cell migration more than the ECM ri

173 toskeletal proteins, we find that increasing stiffness lowers the agonist dose needed for T cell acti

174 1) SVR with DAA-based combination; 2) Liver stiffness (LS) >=9.5 kPa previous to treatment; 3) LS me

175 Liver stiffness (LS) was measured using Vibration Controlled T

176 rce impulse after insertion and the endpoint stiffness magnitude decreased as a function of trials, b

177 vasive echocardiographic-derived index of LV stiffness may be important in LF AS.

178 of PDE9a inhibition to treat high-diastolic stiffness may be limited as the required PDE9a inhibitor

179 resonance elastography (3D-MRE), with shear stiffness measured at 60 Hz, damping ratio at 40 Hz, and

180 Conclusion Mean liver stiffness measured with MR elastography in children with

181 At follow-up, liver stiffness measured with TE was similar among all HIV, LD

182 iver fibrosis (ELF) test with hospital liver stiffness measurement (LSM) for positives, (3) a three-t

183 underwent a comprehensive evaluation; liver stiffness measurements (LSMs) were made by transient ela

184 Alliance, or QIBA, the variability of liver stiffness measurements between systems had decreased.

185 Brain stiffness measurements were corrected with abnormalities

186 tion with cerebrovascular events than global stiffness measures.

187 conditions that varied in shoe sole bending stiffness, modified by carbon fiber plates.

188 le, 72% with type 2 diabetes, baseline liver stiffness of 24.1 +/- 14.2 kPa in F4 disease and 14.6 +/

189 Metabolic savings were maximized (4.2%) at a stiffness of 50 Nm rad(-1).

190 withdrawal, and weaken skeletal strength and stiffness of A. vastus.

191 ed a squat-to-stand motion and optimized the stiffness of an assistive device placed at the knee.

192 hylene glycol) star polymer, we can tune the stiffness of covalent adaptable hydrogels using differen

193 Although the LV myocardial stiffness of patients with LVH is greater than that of h

194 analysis also shows that the characteristic stiffness of quasilocalized nonphononic excitations can

195 CTT with the tubulin body contributes to the stiffness of the assembled microtubule, thus providing i

196 Particularly, it is shown that the bending stiffness of the biomimetic scale covered beam can be ac

197 this study was to evaluate the thickness and stiffness of the diaphragm, using ultrasound (US) and st

198 -forming proteins significantly increase the stiffness of the DNA chain instead (similar to the DNA-s

199 echanics have assumed values of the flexural stiffness of the envelope based on simple scaling argume

200 transmitting tracts actively respond to the stiffness of the environment.

201 exercise causes tendon cells to increase the stiffness of the extracellular matrix; this adaptation m

202 may additionally influence the longitudinal stiffness of the foot and thus the curvature-stiffness r

203 ects of PS training on vascular function and stiffness of the involved (femoral and popliteal) and un

204 Brody disease is an exercise-induced muscle stiffness of the limbs, and often of the eyelids.

205 porosity, the interfiber fusion enhanced the stiffness of the mat by 60%, which is independent of the

206 ranges of porosities, bonding increases the stiffness of the mat; however, the bonding is more effec

207 In addition, we show that increased stiffness of the microenvironment also induces phosphory

208 regulate processes associated with increased stiffness of the microenvironment in the organoid models

209 sed in the organoid model of MCF10A when the stiffness of the microenvironment is increased to that o

210 ogeneity are quantified as a function of the stiffness of the microenvironment using BioSig3D.

211 investigated as a function of the increased stiffness of the microenvironment within the range of MD

212 An experiment has been designed where the stiffness of the microenvironment, in 3D culture, has be

213 both cell lines as a result of the increased stiffness of the microenvironment.

214 a convenient template to tailor the bending stiffness of the underlying slender substrate due to the

215 salt bridge pairing creates the exceptional stiffness of these helical rods, with a persistence leng

216 sion inhibitors) on the porous structure and stiffness of three types of multispecies biofilms.

217 nal association between an increase in liver stiffness on MRE and fibrosis progression in NAFLD.

218 A 15% increase in liver stiffness on MRE may be associated with histologic fibro

219 d to explore the role of calcified-cartilage stiffness on the biomechanics of healthy and pathologica

220 Here, we elucidated the impact of matrix stiffness on the mechanical mode of invadopodia activity

221 In order to probe the effect of substrate stiffness on tumor related cells in greater detail, we c

222 thanum over 96 weeks did not affect arterial stiffness or aortic calcification compared with placebo.

223 P geometry (J-shape versus C-shape), but not stiffness or height, affects v(max) in athletes with uni

224 K2 supplementation did not improve vascular stiffness or other measures of vascular health in this t

225 le density or detyrosination reduced myocyte stiffness, particularly at diastolic strain rates, indic

226 ed to have extraordinarily high strength and stiffness per weight, but have been challenging to fabri

227 Corneal stiffness plays a critical role in shaping the cornea wi

228 In breast cancer, increased ECM stiffness promotes epithelial-to-mesenchymal transition

229 (2D) culture studies indicate that increased stiffness promotes invadopodia degradation activity.

230 launches and tracks shear waves to estimate stiffness, provides an attractive non-contact probe of c

231 ECV positively correlated with LA stiffness (r = 0.45, p = 0.04).

232 agnetic resonance elastography-derived liver stiffness (r = 0.47 vs. r = 0.29; Meng test p = 0.07), g

233 Vascular function improved and arterial stiffness reduced in the arteries involved and uninvolve

234 ported a causal relationship between stromal stiffness, reduced miR-203, higher levels of the murine

235 c arterial pressures and with total arterial stiffness, regardless of the preload dependence status (

236 stiffness of the foot and thus the curvature-stiffness relationship of the transverse tarsal arch.

237 lculated from the baseline chronological age-stiffness relationship.

238 This undamped stiffness remains constant in the range of sarcomere len

239 he relationship between midfoot geometry and stiffness remains debated in foot biomechanics(12,13), p

240 breast tissue identified miR-203 as a matrix stiffness-repressed transcript that is downregulated by

241 ew method simplifies interpretation of liver stiffness results and is more clinically relevant.

242 ior of biomimetic beams covered with tunable stiffness scales of two architectures-one with single en

243 ssembled shells can produce close to optimal stiffness scaling with density, and we experimentally de

244 lacks the complete reorganization for torso stiffness seen in extant great apes (i.e., living member

245 racteristic movement difficulty (eg, tremor, stiffness, slowness), and psychological or cognitive pro

246 = - 0.36, 95% CI - 0.62 to - 0.10) and WOMAC stiffness (SMD = - 0.47, 95% CI - 0.71 to - 0.23) subsca

247 The hydrogel layers exist in a higher stiffness state that prevents inter-reservoir or leakage

248 exhibit super-rapid and significant hikes in stiffness, strength, and toughness by up to 1800-, 80-,

249 0.59, 0.47 and 0.41, respectively for WOMAC stiffness subscale, 0.05, 0.57 and 0.53, respectively fo

250 ference, -1.1 [95% CI, -1.5 to -0.7]), WOMAC stiffness subscore (between-group difference, -1.4 [95%

251 measures of arterial endothelial function or stiffness, systemic inflammation, or lipid profile, but

252 3 and 6 mo in endothelial function, arterial stiffness, systemic-systolic BP, lipids, and inflammator

253 wer AAT inclusions in liver, and lower liver stiffness than adults with the Pi*ZZ genotype, but highe

254 nd flow data are more sensitive to increased stiffness than using flow or pressure pulsatility indice

255 vironmental rigidity-dependent intracellular stiffness that increases with intracellular stress - a r

256 prosthetist subjects indicated the change to stiffness that they would prefer (increase or decrease).

257 Background Stiffness thresholds for liver MR elastography in childr

258 a novel echocardiography-derived index of LV stiffness to compare between these groups.

259 tion allowing movement is more relevant than stiffness to improve balance and prevent falls.

260 sing training forces, prompting local crease stiffnesses to change in proportion to their experienced

261 f these design characteristics yield a local stiffness two orders of magnitude smaller than the corre

262 mere have been reported to exhibit a similar stiffness under both positive and negative forces.

263 er fibrosis was estimated by measuring liver stiffness using transient elastography (TE) and magnetic

264 ler imaging with iontophoresis, and arterial stiffness, using pulse wave analysis.

265 urves enables the measurement of DNA origami stiffness values at the enthalpic elasticity regime, i.e

266 EV stiffness values measured with our high-throughput metho

267 rous bone mimics, which indicates a range of stiffness values that prevents impact force from becomin

268 based on the probability of cACLD for given stiffness values.

269 code' aspects of muscle force, yank, length, stiffness, velocity, and/or acceleration, providing an e

270 The 95th percentile of normal liver stiffness was 2.8 kPa.

271 baseline, median MRI-PDFF was 16.3% and MRE-stiffness was 3.27 kPa.

272 MR elastography-based liver stiffness was an independent predictor for LGE (odds rat

273 Change in stiffness was assessed at the ascending (Ao-A) and desce

274 Arterial stiffness was assessed in two medical examinations (2007

275 LA stiffness was calculated as the ratio of echocardiograph

276 he average power spectrum, their interfacial stiffness was determined according to the capillary fluc

277 Carotid beta-stiffness was greater in older women than men (6.7 +/- 2

278 arotid-radial artery PWV, PWV(CR) ) arterial stiffness was measured by pulse-wave velocity (PWV), tog

279 Carotid beta-stiffness was measured with B-mode ultrasonic image and

280 LA stiffness was moderately associated with increased TRV (

281 sure - right atrial pressure), LV myocardial stiffness was nearly 30% greater in LVH than in controls

282 No acute effect on passive muscle stiffness was observed.

283 Passive cardiomyocyte stiffness was reduced by chronic PDE9a inhibition, with

284 Increased LV stiffness was related to LV concentric remodelling and d

285 ultivariable mixed-effects regression, brain stiffness was significantly associated with the presence

286 and 95% confidence intervals (CIs) for liver stiffness were calculated.

287 Contact time and leg stiffness were more asymmetric using the RSP model that

288 in Enhanced Liver Fibrosis scores and liver stiffness were not observed.

289 For the (100) and the (114) interfaces, the stiffnesses were 0.15 and 0.18 [Formula: see text] (sigm

290 arity of the ability to regulate ankle joint stiffness when compared to the abilities to regulate joi

291 gly and exponentially depends on the bending stiffness, which accounts for more than half the measure

292 ssel Endothelial Growth Factor, adhesion and stiffness, which are incorporated to a Cellular Potts mo

293 a, microglia contacts the deep layer of high stiffness, which coincides with microglial bipolarizatio

294 isabling and incurable contractures, or limb stiffness, which result from proteasome-mediated protein

295 r system to voluntarily regulate ankle joint stiffness while seated, and compare these data to the we

296 stasis have the fastest migration and lowest stiffness, with a significantly higher capacity to trans

297 ed in a significant increment of the nanoMIP stiffness, with the mean Young's modulus measured by AFM

298 cent clinical studies have measured regional stiffness within the aortic arch using pulse wave veloci

299 ions for binding interactions and modulating stiffness within the ECM.

300 s of 3D colony formations indicate that high stiffness, within the range of high MD, and X-ray radiat