ライフサイエンスコーパス: strategy to

1 es gradually changed from a more exploratory strategy to a more conservative way of exploiting resour

2 ding another successful example of a general strategy to accelerate catalyst development which still

3 Multitarget synthetic strategies to access novel photochromic 3H-naphtho[2,1-b

4 We have developed an efficient synthetic strategy to access 2,5-diaryl nonsymmetric furans from 5

5 The evolution of a strategy to access the family of rearranged spongian dit

6 However, developing simple and efficient strategies to achieve product separation and catalyst an

7 relevance of isoform differentiation, design strategies to achieve selectivity, and applications in b

8 Two identified key strategies to achieve this were as follows: 1) a new aut

9 MEK inhibitors, although potential for this strategy to achieve cure remains uncertain.

10 In HPTN 078, which assessed an integrated strategy to achieve HIV viral suppression, 1305 MSM were

11 ovel atom-confinement and coordination (ACC) strategy to achieve the synthesis of rare-earth single e

12 d utilizes both an existing ion multiplexing strategy to achieve up to an 8-fold gain in ion signal a

13 ized RNAP that employs two (MglA-SspA)-based strategies to activate virulence genes.

14 Here we report a strategy to activate the low-temperature performance of

15 nd emerging screening methods, and potential strategies to address current limitations in CRC screeni

16 h systems have developed multiple mitigation strategies to address emergency department boarding of c

17 Contributing factors and strategies to address this are poorly understood.

18 moting research to further explore practical strategies to address, mitigate, and prevent burnout.

19 and prompt treatment rely on a sophisticated strategy to address the contributing factors.

20 th a positive result has been suggested as a strategy to address the coronavirus disease 2019 (COVID-

21 Encouragingly, this work provides a novel strategy to address the imperious demands for OLEDs with

22 imens during radiotherapy and for developing strategies to alleviate radiotherapy-induced toxicity to

23 Straw return is an effective strategy to alleviate soil-borne diseases.

24 arrestin2 oligomeric status represents a new strategy to alleviate tau pathology in FTLD and related

25 s demonstrated that alloying is an effective strategy to alleviate this problem.

26 Most strategies to alter seed oil composition involve the ove

27 s hypothesis using two potential therapeutic strategies to alter the lipoprotein/protein profile of t

28 We then apply the strategy to an integral membrane protein by comparing th

29 n activator receptor (uPAR) as a therapeutic strategy to attenuate acute kidney injury in transgenic

30 Rigorous evaluation of strategies to augment vaccine-induced control of carriag

31 sited stroke outcome predictions by applying strategies to avoid confounds and fitting hierarchical B

32 ive and false-positive results, and provides strategies to avoid costly and potentially fatal misdiag

33 enerate reactive oxygen species is used as a strategy to avoid adding H(2)O(2) in the solution during

34 his natural resource is sometime viewed as a strategy to avoid water waste.

35 ion, annotation, preprocessing, and learning strategies to be made and scrutinized more transparently

36 tes, demonstrating the need for intervention strategies to be tailored to individual settings.

37 Finally, we look toward the future at strategies to better identify people at risk for AKI and

38 terial pathogens is emerging as an important strategy to better understand host-pathogen interactions

39 The influenza A virus deploys this strategy to bind strongly to cell surface receptors.

40 d biochemical studies and provides a general strategy to block Streptococcus pneumoniae IgA1 protease

41 ntrathecally targeting sTNFalpha as a viable strategy to broadly attenuate sympathetic dysregulation,

42 op-down proteomics has emerged as a powerful strategy to characterize proteins in biological systems,

43 Here, we apply a barcoding strategy to clonal tracking of edited cells (BAR-Seq) an

44 uggest that targeting c-Myc may unlock novel strategies to combat asthma or asthma exacerbation.

45 l of this symposium was to identify the best strategies to combat gastric cancer in the AN population

46 Thus, treatment strategies to combat metabolic dysfunction are needed.

47 Prokaryotes have developed numerous defense strategies to combat the constant threat posed by the di

48 reby elucidating a potential new therapeutic strategy to combat AMD.

49 BPTF inhibition is a promising strategy to combat HGG through epigenetic regulation of

50 this may be generalized to enable molecular strategies to complement heterogeneous catalysts by stab

51 rst vaccine catalyzed the development of new strategies to control Lyme disease that bypassed direct

52 w insights for the development of innovative strategies to control protein function and tune producti

53 on may help provide a useful new alternative strategy to control ovarian tumor progression based on s

54 ke is a potentially useful immunosuppressive strategy to control skin inflammation mediated by the IL

55 nd treat individuals with SUD as part of the strategy to control the pandemic while ensuring no dispa

56 Our results outline a potentially general strategy to convert RTKs into photoreceptors.

57 ondrial oxidative phosphorylation are common strategies to cope with high-altitude hypoxia, but some

58 bility, safety, and effectiveness of a novel strategy to correct acidemia through extracorporeal chlo

59 loride concentration could be an alternative strategy to correct acidemia.Objectives: To evaluate fea

60 POC testing is a promising strategy to cost-effectively improve patient outcomes in

61 One strategy to counteract neurodegeneration is to promote n

62 Self-assembly is a bioinspired strategy to craft materials for renewable and clean ener

63 opment of a multimodal and multidisciplinary strategy to create an optimal perioperative condition to

64 is study provides a proof of principle for a strategy to create protein-level cell barcodes that can

65 Inhibiting GSDMD is an attractive strategy to curb inflammation.

66 explored, but provide a powerful alternative strategy to current approaches, considerably extending t

67 These results underscore the need for strategies to deal with intraseasonal vaccine effectiven

68 We identified 6 types of behavioral strategies to decrease opioid prescription at discharge

69 Strategies to decrease the rate of unnecessary invasive

70 ing Siglec-8 with an antibody is a plausible strategy to decrease sputum eosinophils and inhibit lung

71 t study, we employed a substrate competition strategy to demonstrate DapF (Ct) function in vivo in C.

72 Our study then suggests two strategies to design next-generation fouling-resistant R

73 imulate the chemists to explore new chemical strategies to design safer products, composites and devi

74 Here we demonstrate a strategy to design adsorbents that utilizes the tunabili

75 ho practice receptive AI may need additional strategies to detect anal chancres, to reduce transmissi

76 dition of surfactant) is also an interesting strategy to detect current spikes corresponding to singl

77 web server that couples a graph mining-based strategy to detect motifs at the protein-ligand interfac

78 monstrate the use of differential expression strategies to determine true parasite-derived sRNAs with

79 m and QUE and/or RES should be an innovative strategy to develop added-value nutraceutical formulatio

80 These findings suggest a new strategy to develop an innovative heterogeneous catalyti

81 Herein, we demonstrate a strategy to develop efficient and stable lanthanide coor

82 2-year mortality incorporating an LB or NIT strategy to diagnose cirrhosis in a hypothetical cohort

83 mple, small budding cells use very different strategies to disseminate compared with long hyphal fila

84 further development of personalized medicine strategies to effectively treat MDD.

85 This paper presents a solid-phase strategy to efficiently assemble multiprotein scaffolds-

86 mployed a sequential reduction and oxidation strategy to efficiently refold two high-yielding monomer

87 We used a different strategy to emulate such local heterogeneity by forming

88 study demonstrates the use of ML as a viable strategy to enable personalized risk quantification for

89 pulation is feasible and represents a viable strategy to end the pandemic.

90 Herein, a ligand-assisted surface matrix strategy to engineer the surface and packing states of P

91 First, we offer strategies to enhance patient engagement in trial design

92 This study aimed at investigating two strategies to enhance the bioaccessibility of phenolic c

93 These include the definition of response, strategies to enhance the responder rate, the duration o

94 infectious agents; however, to date specific strategies to enhance Trm responses at this site are lac

95 as an effective, safe yet technically simple strategy to enhance brain delivery of darunavir and pote

96 -delocalizing ligands (EDLs)" is a promising strategy to enhance coupling of QD excitons with proxima

97 One proposed strategy to enhance delivery across endothelial or epith

98 glucose uptake could be an early postpartum strategy to enhance lactation success in women at risk f

99 ffector functions and offers a potential new strategy to enhance outcomes after allo-HSCT.

100 The study highlights a strategy to enhance the efficacy of cancer immunotherapy

101 an be leveraged as a previously unrecognized strategy to enhance treatment responses.

102 atory elements in crop plants is a promising strategy to ensure food security.

103 mortality, and each has evolved specialized strategies to establish and maintain their replicative n

104 cteriophages, have in turn evolved different strategies to evade these hurdles.

105 -sucking parasites, have developed a complex strategy to evade and suppress host immune responses dur

106 Strategies to expand tuft cells might be developed for t

107 e use of young blood factors may be a useful strategy to expand adult beta cell mass.

108 Here, we demonstrate a water-incorporation strategy to expand the interlayer gap of alpha-MoO(3), i

109 hanisms for genomic instability and targeted strategies to exploit these defects in the treatment of

110 dy provides useful resources and gene mining strategies to explore complex quantitative traits.

111 Herein we developed a general host-guest strategy to fabricate various metal single-atom catalyst

112 followed by chemical enrichment or depletion strategies to facilitate their detection via mass spectr

113 nt, and merits study as a potential clinical strategy to facilitate transplant acceptance.

114 naling plasticity is a general cross-kingdom strategy to fend off pathogens.

115 ly been recognized as an increasingly viable strategy to forge challenging C-C and C-heteroatom bonds

116 A synthetic strategy to fused bicyclic piperidines-building blocks f

117 action, wasps and their hosts have coevolved strategies to gain an advantage in this evolutionary arm

118 need for improved diagnostic/risk prediction strategies to guide antibiotic prescribing for suspected

119 ird species could be an effective management strategy to help reduce ciprofloxacin-resistant E. coli

120 mission, clinicians have a care coordination strategy to identify and manage impairments across the c

121 We furthermore present a straightforward strategy to identify both nonbiotinylated and biotinylat

122 Here, we established a screening strategy to identify drugs that reduce ACE2 levels in hu

123 ng HBeAg and ALT level could be an effective strategy to identify HBV-infected pregnant women at risk

124 This work reports a simple and powerful strategy to identify HCPs in antibody drug substance by

125 ractionation and a multi-step peptide search strategy to identify peptides generated by various types

126 We developed a structural engineering strategy to immobilize a molecular catalyst tetrakis(4-m

127 rly and effective use of anticoagulation and strategies to improve brain perfusion through rhythm and

128 hout compromising total milk fat, suggesting strategies to improve dairy animals' milk composition wi

129 Systematic assessment and strategies to improve frailty might reduce infection ris

130 anding and inform the design of preventative strategies to improve long-term consequences of the synd

131 Additional investigation into strategies to improve long-term outcomes in eyes with DM

132 drug discovery efforts are also focusing on strategies to improve patient convenience through altern

133 Strategies to improve patients' tolerance of and adheren

134 it is essential to design novel therapeutic strategies to improve the prognosis for breast cancer pa

135 ic devices and stimulated the development of strategies to improve their thermoelectric performance.

136 ti-VEGF therapy as well as studies examining strategies to improve this were included.

137 onent new-chemical-entity nanomedicine (ONN) strategy to improve cancer therapy through incorporation

138 A damage repair is proposed as a therapeutic strategy to improve outcomes for patients with solid tum

139 on or additional optical paths, is a popular strategy to improve sample coverage.

140 We demonstrate a strategy to improve the binding affinity of aptamers by

141 ived vesicles may be a promising therapeutic strategy to improve the efficacy of chemotherapy treatme

142 troducing trifluoromethyl groups is a common strategy to improve the properties of biologically activ

143 This work demonstrates a novel strategy to improve the sensing performance of a prism-c

144 nvestigation of the co-administration dosing strategy to improve the tumor penetration of ADCs.

145 We proposed a new computational strategy to impute the methylation value at the unmeasur

146 Here, we developed a new strategy to incorporate T cells into human 3D skin const

147 ll enable the development of modern breeding strategies to increase and stabilize white lupin yield.

148 the capacity of IL-2-based immunotherapeutic strategies to increase their antiviral function.

149 Other strategies to increase tissue cyclic guanosine monophosp

150 red onto supports provided another effective strategy to increase both the atomic efficiency and the

151 Inhibition of sEH is used as a strategy to increase EET levels leading to lower inflamm

152 fortification is an effective and economical strategy to increase micronutrient intakein countries wh

153 , and how inhibiting NMD may be an effective strategy to increase the efficacy of cancer immunotherap

154 re, eCO(2) treatment represents an efficient strategy to increase the hypocholesterolaemic, antioxida

155 Thus far, the most successful strategies to induce suppression of graft rejection reli

156 r, selective activation of MC(1) is a viable strategy to induce cellular senescence, affording a dist

157 , including a highly regulatable CRISPR/Cas9 strategy to induce DNA double strand breaks specifically

158 All viruses require strategies to inhibit or evade the immune pathways of ce

159 lation of COVID-19 cases and is an important strategy to interrupt SARS-CoV-2 transmission.

160 ine was applied as an alternative alkylation strategy to introduce artificial tryptic cleavage sites

161 3 identifies human tTreg cells and provide a strategy to isolate such cells for safer and more effica

162 pathophysiological mechanisms, would suggest strategies to limit graft failure.

163 l later lines of therapy may be a reasonable strategy to limit health care costs without compromising

164 Here, we report a strategy to link molecules and 1D ribbons into 2D cystal

165 Pathogens, in turn, develop successful strategies to maintain access to bioavailable metal ions

166 ction, may aid in the search for therapeutic strategies to manage PD and related neuropathologies.

167 stant eucalypt genotypes have been the major strategies to manage the disease in Brazil, the molecula

168 As such, identification of strategies to manipulate habenular activity may yield ap

169 In addition, pathogens use many strategies to manipulate host cell death pathways to fac

170 tor exclusively activated by designer drugs) strategy to manipulate vHPC-NAc excitability directly in

171 is important to those who could benefit from strategies to maximize preventive measures.

172 ent and regular patterns of spore release as strategies to maximize spore survival in the air.

173 Our results suggest that an effective strategy to maximize bnAb evolution is through a sequent

174 inators Group, has implemented an assessment strategy to measure quality and impact of its entire tra

175 d Platelet Inhibition to Clarify the Optimal Strategy to Medically Manage Acute Coronary Syndromes) w

176 ) in transgenic crops represents a promising strategy to meet our demands for specialized plant oils

177 ilding a robust, stable network must include strategies to minimize perturbations caused by environme

178 nging NHP model, this study proposes a novel strategy to minimize the number of donor islets required

179 re, we further discuss practical methods and strategies to mitigate catalyst and electrode degradatio

180 and increased societal dependence on future strategies to mitigate climate warming.

181 Finally, we also discuss emerging strategies to mitigate photocorrosion (such as surface p

182 Tools and strategies to mitigate the extreme and multiple resistan

183 We implemented a heterobivalent design strategy to modulate the potency, selectivity, and bindi

184 Imaging strategies to monitor chimeric antigen receptor (CAR) T-

185 scent protein (GFP)-tagging is the prevalent strategy to monitor protein dynamics in living cells.

186 g to our findings, Brazil would benefit from strategies to more accurately identify women at higher r

187 lic networks de novo, organisms have evolved strategies to neutralize the impact of oxygen that can b

188 Herein, a novel strategy to obtain micropatterned graphene on polymer su

189 bypass grafting-related GUSTO (Global Use of Strategies to Open Occluded Coronary Arteries) severe/li

190 We anticipate this strategy to open new doors and facilitate exciting advan

191 These findings may inform rapid response strategies to optimize health care delivery in parts of

192 ll-directed therapeutics in MS, and proposes strategies to optimize the use of existing anti-B-cell t

193 Mode switching likely provides a general strategy to optimize perceptual processes.

194 ring is a highly effective molecular design strategy to optimize the thermoelectric performance of c

195 e potential of applying our machine learning strategy to other diseases and purposes such as in desig

196 w potential target molecules for therapeutic strategies to overcome 5-FU resistance.

197 ells, to solid tumors requires combinatorial strategies to overcome immune suppression associated wit

198 subsequent treatment approaches and suggest strategies to overcome or prevent osimertinib resistance

199 h and economic value; however, complementary strategies to overcome social and structural barriers to

200 ng a critical reconsideration of engineering strategies to overcome the coercivity limits.

201 hat hinder tissue-specific drug delivery and strategies to overcome them.

202 of ART-suppressed HIV-1 infection, we tested strategies to overcome these limitations and challenges.

203 mune landscape offers insights into possible strategies to overcome tumor-supporting TME properties a

204 pathways downstream of AR could be a viable strategy to overcome CRPC.

205 hermore, we develop a slow sustained-release strategy to overcome the limited dispersibility of prote

206 nd targeting SHP2 may serve as a therapeutic strategy to overcome tumor resistance to osimertinib.

207 The introduction of chemical strategies to parse and enrich subsets of the "functiona

208 Here, we report a strategy to partition acs framework into pacs (partition

209 n comparing the utilization of best practice strategies to patients who did not have these conjointly

210 This provides a geroscience strategy to potentially rejuvenate oral health and rever

211 We proposed Graph-based Residue neighborhood Strategy to Predict binding sites (GRaSP), a novel resid

212 enables the development of novel conjugation strategies to prepare antibody-TNM conjugates.

213 Reported here is a strategy to prepare chiral AgNP arrays templated by two

214 We extended this strategy to prepare Hf(12) -Ru-Co-OTf MOL with a [Ru(DBB

215 Strategies to prevent arterial stiffening prior to this

216 l or postnatal PHi therapy may provide novel strategies to prevent BPD due to antenatal inflammation.

217 mTBI utilized hip strategies more than ankle strategies to prevent loss of balance and also showed le

218 which warrants for the development of novel strategies to prevent new HIV-1 infections in infants.

219 Developing effective strategies to prevent or treat coronavirus disease 2019

220 rtant to develop more targeted and effective strategies to prevent suicide.

221 Viruses routinely employ strategies to prevent the activation of innate immune si

222 ited availability of alternatives means that strategies to prevent the spread of 3GC resistance are i

223 ants of the high mortality rate in COVID-19, strategies to prevent thrombosis are of critical importa

224 edial olivocochlear system could be a viable strategy to prevent age-related hearing loss.

225 e present study provides a promising genetic strategy to prevent airway bacterial infections in farm

226 vaccination has recently been proposed as a strategy to prevent infection with SARS-CoV-2 (CoV-2) to

227 One strategy to prevent mental illness may be to target inte

228 rgeting Hippo signaling may be a therapeutic strategy to prevent the development and progression of d

229 inhibition could be a potential therapeutic strategy to prevent the irreversible pulmonary failure t

230 hibition of protein glycation could be a key strategy to prevent these diabetic abnormalities.

231 ery systems engineered by aptamer for future strategies to promote human health using this class of h

232 anti-NET treatments could be new therapeutic strategies to promote skin allograft longevity and, henc

233 osis proteins in T2D, with thoughts on novel strategies to protect functional beta-cell mass.

234 proving autophagic flux may be a therapeutic strategy to protect endothelial function from dyslipidem

235 t recombinant uPA is a potential therapeutic strategy to protect the synapse before the development o

236 s associated factors might have underpowered strategies to provide adequate care and prevent its occu

237 e challenges unique to this age group, novel strategies to provide the best preoperative, intraoperat

238 ibroblast differentiation, however practical strategies to raise tissue PGE2 during IPF have been lim

239 bioorthogonality thus appears as a powerful strategy to rapidly access to sugar-based ligands.

240 Furthermore, this study provides a general strategy to rapidly evolve other desired CRISPR-Cas9 tra

241 Previously, we described a strategy to rapidly identify and generate llama nanobodi

242 gh vaccination coverage; some must undertake strategies to reach persons >=15 years of age and close

243 photoinduced post-synthetic copolymerization strategy to realize a membranous ratiometric luminescent

244 hours), providing a pragmatic strategy to redisperse degraded particles for a variety

245 icant barrier to transplantation and current strategies to reduce allosensitization are limited.

246 anism may provide information for developing strategies to reduce infertility-causing pathology induc

247 pidly undertaking research to find effective strategies to reduce the burden of this disease.

248 prove and monitor clinical and public health strategies to reduce the deaths from SARS-CoV-2 infectio

249 Strategies to reduce the development of celiac disease h

250 s a major challenge for developing effective strategies to reduce the disease burden and transmission

251 ll serve as a tool for screening therapeutic strategies to reduce/eliminate HIV reservoirs in opioid

252 ing and cost-effective, or even cost-saving, strategy to reduce child mortality.

253 enhancing foods is considered as a promising strategy to reduce food intake and promote weight manage

254 lovirus (HCMV) during pregnancy is a primary strategy to reduce the incidence of congenital disease.

255 Vaccines offer a promising strategy to reduce the prevalence of opioid use disorder

256 Bacteria developed different strategies to regulate activity of RssB, including phosp

257 into the systemic circulation is a potential strategy to relieve solid tumor hypoxia in order to incr

258 PERK in tumor-MDSC functionality and unveil strategies to reprogram immunosuppressive myelopoiesis i

259 Private practices have crafted tiered strategies to respond to the impact of the pandemic by p

260 Strategies to restore disrupted myocardial calcitonin si

261 reast cancer patients, and may lead to a new strategy to restore anti-tumor immunity by inhibiting pa

262 LC chemoresistance and provide a therapeutic strategy to restore chemosensitivity.

263 ng of PRL2 could provide a novel therapeutic strategy to restore PTEN, thereby obliterating PTEN defi

264 A-Biome may promote the development of novel strategies to restructure the microbiome as a means of p

265 d tested potential pharmacological treatment strategies to retard its progression in vivo.

266 lls, in combination with immune intervention strategies, to reverse the disease.

267 and structural features and used a two-step strategy to select the relevant features.

268 micals, and ligands for metal complexes, but strategies to selectively halogenate pyridine C-H precur

269 s) compete in dynamic environments, evolving strategies to sense the milieu.

270 We develop a strategy to simulate single-cell transcriptional data fr

271 g HDL interactions with BrM represents a new strategy to slow AMD progression in humans.

272 synthetic LXR agonist as a novel therapeutic strategy to stimulate antitumor activity.

273 e diversity of patients enrolled, evaluating strategies to streamline registries and the study of uns

274 , and evaluated a wide range of intervention strategies to support caregivers.

275 perative risk stratification and investigate strategies to support younger patients who are frail.

276 modulate host circadian clock as a potential strategy to suppress host innate immunity is not well un

277 d high throughput solvent-free self-assembly strategy to synthesize a series of MMOs including single

278 otic stress response and help develop better strategies to tackle foodborne staphylococcal infections

279 on has been investigated as a cost-effective strategy to tackle U contamination in the subsurface.

280 ghts into the development of new therapeutic strategies to target mast cells during anaphylaxis or ot

281 ary and metastatic TMEs and discuss emerging strategies to target metabolic communications for improv

282 tists from different fields to develop newer strategies to target microorganisms responsible for infe

283 o likely useful in designing new therapeutic strategies to target nucleolar dysfunction.

284 Strategies to target PGE(2) might be developed for treat

285 e wide-reaching due to the potential for new strategies to target resistance development.

286 challenges that ROS1 fusions present and the strategies to target ROS1 fusion proteins in both treatm

287 Strategies to target the increased risk of visual axis o

288 We demonstrate a novel viral gene expression strategy to target cells with specific miRNA expression

289 We devised a novel strategy to test the phenotypic impact of individual mic

290 e present a time-resolved chemical proteomic strategy to track the early-stage entry of ZIKV into hos

291 The current work demonstrates an effective strategy to transform an n-type g-C(3)N(4) photoanode ma

292 Novel strategies to treat ALD aim at targeting Kupffer cells.

293 has been proposed as one of the therapeutic strategies to treat individuals with metabolic syndrome,

294 s, this information has not led to effective strategies to treat RB1-deficient tumors, as it is chall

295 tion of VEGF has been the clinically adopted strategy to treat colorectal and breast cancers as well

296 RNA therapeutics are a promising strategy to treat genetic diseases caused by the overexp

297 These studies demonstrate a strategy to tune RNA structure-targeting compounds to th

298 The proposed mechanisms indicate strategies to understand and control crystallization in

299 somerization is likely a practical enzymatic strategy to unmask the strong oxidizing power of sMMO-Q

300 We apply this strategy to various substrates-including silicon, cerami