ライフサイエンスコーパス: stress response

1 al regulation program called the 'integrated stress response'.

2 gative stressful stimuli (here, shortened to stress response).

3 and inflammation is regulated during hepatic stress response.

4 death is an important component in the coral stress response.

5 gesting they may have functions in oxidative stress response.

6 that plays an important role in replication stress response.

7 ted growth-suppressive pathway for oxidative stress response.

8 within the NAc plays a critical role in the stress response.

9 disorder seems to be a common, low-fitness, stress response.

10 molecular pathways involved in the podocyte stress response.

11 ment, tissue homeostasis, and in particular, stress response.

12 rmate hydrogenlyase complex, and the general stress response.

13 he contributions of gonadal hormones to this stress response.

14 lant flowering, seed development and abiotic stress response.

15 functions in the endoplasmic reticulum (ER) stress response.

16 ase (CrRLK1L) and others involved in abiotic stress response.

17 physiological functions of YAP, in the heat stress response.

18 s involved in the endoplasmic reticulum (ER) stress response.

19 d in anxiety behaviour and regulation of the stress response.

20 ng regulatory roles for 6mA in mitochondrial stress response.

21 aromyces cerevisiae, including the oxidative stress response.

22 le of the GABAergic system on the behavioral stress response.

23 er's ability to induce endoplasmic reticulum stress response.

24 to a single network, the mitoprotein-induced stress response.

25 tabolic activation, DNA damage response, and stress response.

26 role of mitochondrial dynamics in organismal stress response.

27 olved in DNA recombination and the oxidative stress response.

28 ation of PrimPol to regulate the replication stress response.

29 starvation and activation of the integrated stress response.

30 ) coral genes that may play key roles in the stress response.

31 ription factor of endoplasmic reticulum (ER) stress response.

32 ism, endoplasmic reticulum function, and the stress response.

33 -dependent expression of immune function and stress response.

34 ting of how individual differences shape the stress response.

35 articular those associated with the cellular stress response.

36 nging free radicals in wolfberries oxidative stress response.

37 (eIF2alpha), which orchestrates the cellular stress response.

38 roduction in low producers is a finely tuned stress response.

39 and triggering an endoplasmic reticulum (ER) stress response.

40 d effects on adult physiology, including the stress response.

41 oles in both normal plant development and in stress responses.

42 r HR variability, reflecting lower autonomic stress responses.

43 h the induction of systemic inflammatory and stress responses.

44 a multistage catabolic process that mediates stress responses.

45 with gene expression, plant development, and stress responses.

46 persistence of fear memories and maladaptive stress responses.

47 cal roles in the regulation of fertility and stress responses.

48 but dispensable for SpxA2-mediated envelope stress responses.

49 nd H(2)O(2)-released from roots during plant stress responses.

50 ll-to-cell signaling, biofilm formation, and stress responses.

51 ess-related factors and minimal induction of stress responses.

52 linking acetyl-CoA fluctuations to cellular stress responses.

53 timing signals to control developmental and stress responses.

54 nd microbes respond through metal starvation stress responses.

55 barriers, genetically encoded antidotes, and stress responses.

56 king effects on cells, such as activation of stress responses.

57 atin modification to control development and stress responses.

58 s heme to counteract antimicrobial oxidative stress responses.

59 nts suggested a function of NatB in multiple stress responses.

60 ng cancer leads to activation of replication stress responses.

61 rug resistance, such as regulators of fungal stress responses.

62 pport is itself often linked to dysregulated stress responses.

63 discuss the roles of BRs in development and stress responses.

64 , a member of HD-ZIP I subfamily, in abiotic stress responses.

65 highly versatile signal that induces various stress responses.

66 sed to control CAMTA3 functions in different stress responses.

67 for this USP in mycobacterial physiology and stress responses.

68 llular homeostasis during development and in stress responses.

69 nvolved in fear extinction and regulation of stress responses.

70 ociated with cell division, development, and stress responses.

71 ere developmental defects as well as induced stress responses.

72 s, functions in seed germination and abiotic stress responses.

73 tions in yeast, flies and mammals, including stress-responses.

74 that cells unable to activate this sigma(I) stress response acquire gain-of-function mutations in th

75 liver redox variation and explore how other stress responses affect cholangiocyte injury in BA.

76 n, is an evolutionarily conserved epigenetic stress response, also implicated in several human diseas

77 vailable effect data, 17% elicited oxidative stress response and 18% activated the arylhydrocarbon re

78 Viscoadaptation functions as a stress response and a homeostatic mechanism, allowing ce

79 in stress in the context of health; (b) the stress response and allostatic load; (c) some of the key

80 tinct temporal patterns in our yeast osmotic stress response and axolotl limb regeneration case studi

81 novel ER stress suppressor, in As-induced ER stress response and cytotoxicity in neural cells.

82 d ribosomal processing of mRNAs critical for stress response and decreased CSC-related proteins inclu

83 ipening, softening, cell wall strengthening, stress response and disease resistance were differential

84 sulted in up-regulation of genes involved in stress response and down-regulation of the MalaS7 allerg

85 tarting point for future research on osmotic stress response and help develop better strategies to ta

86 omal adaptor Tollip during the mitochondrial stress response and identify its interaction and colocal

87 ineate a novel role for Slug in the nutrient stress response and provide insight into how nutrient de

88 in two seemingly distinct pathways, membrane stress response and regulation of nutrient transporters.

89 ge, which triggers the endoplasmic reticulum stress response and subsequent eicosanoid and cytokine s

90 d the involvement of TRIM21 in the genotoxic stress response and suppressing tumorigenesis.

91 that AEA signaling can temper aspects of the stress response and that FAAH inhibition may aid the tre

92 inding protein associated with the oxidative stress response and that this molecular function is like

93 thates for flowering, rhizome fortification, stress response and tissue-specific secondary metabolite

94 s (ELS) induces long-lasting consequences on stress responses and emotional regulation in humans, inc

95 transferase, implicated in the regulation of stress responses and genome stability.

96 for a SIK1/HDAC7 axis in regulating cardiac stress responses and implicate this pathway as a potenti

97 trols the balance between biotic and abiotic stress responses and is a master regulator of plant-envi

98 iption factors (TFs) are involved in abiotic stress responses and plant development.

99 identify JNK as a potential conduit linking stress responses and reproductive success in the most im

100 of RNAP, with potential effects on cellular stress responses and survival.

101 ndicate that NLR signaling represses osmotic stress responses and that BON proteins suppress NLR sign

102 ses that may significantly impact individual stress responses and therefore predisposition to autoimm

103 d, an in vivo network consisting of selected stress-response and cambium regulators indicated ERF-1 a

104 uggesting that reciprocal regulation between stress-response and growth-control pathways occurs at mu

105 P) plays critical roles in nutrient sensing, stress response, and cell growth.

106 lated genes are involved in unfolded-protein stress response, and cells exposed to m-Tyr contained la

107 important area of the brain involved in the stress response, and higher activation with acute mental

108 lbicans drug-efflux, regulation of oxidative stress response, and maintenance of cell membrane integr

109 ourse, neuroinflammation, and the autophagic stress response, and may help identify novel therapeutic

110 with defects in DNA repair, the replication stress response, and/or transcriptional activation.

111 to regulation of stem cell differentiation, stress responses, and, potentially, amelioration of neur

112 d by replacement with paralogs MItochondrial STress Response AntiViral (MISTRAV) and/or MItochondrial

113 ircuitry implicated in the regulation of the stress response are associated with reduced peripheral p

114 d proteins involved in prokaryotic oxidative stress response are rare, we sought to learn more about

115 heless, nonapoptotic cell death and adaptive stress responses are also activated following genotoxic

116 Stress responses are particularly important in stem cell

117 CED DISEASE RESISTANCE 1 (EDR1), ensure that stress responses are properly suspended when they are no

118 the aryl hydrocarbon receptor and oxidative stress response (AREc32).

119 vely, our findings reveal the REDD1-mediated stress response as a novel tumor suppressor whose loss d

120 al cortisol levels control acute and chronic stress response, as well as contribute to diseases and s

121 nown to impact growth and to elicit specific stress responses at extreme values; it is often used as

122 anscript as part of a dual output xbp-1 mRNA stress response axis.

123 Variation in stress responses between individuals are linked to facto

124 unraveling the transmission and buffering of stress responses between individuals, but little is know

125 for SpxA1-dependent activation of oxidative stress responses but dispensable for SpxA2-mediated enve

126 pecies are key players in biotic and abiotic stress responses, but there is no consensus on whether e

127 CN3) are endocrine hormones that control the stress responses by activating CRF1R and CRF2R, two memb

128 temporal resolution of our knowledge of salt stress responses, (c) discovering and considering crop-s

129 min 2 (INF2), an actin regulator, mediates a stress response-calcium mediated actin reset, or CaAR-th

130 te such limitations, it is unclear whether a stress-response can be universally captured.

131 obal expression of genes for ROS production, stress response, carbohydrate transmembrane transport, s

132 ion activates the endoplasmic reticulum (ER) stress response, causes oxidative stress, and induces ap

133 Stress response, cellular response to DNA damage, iron i

134 activity and functional connectivity of the stress response circuitry and variations in cardiovagal

135 ne sensing or the endoplasmic reticulum (ER) stress response contributes to the changes in m(6)A in R

136 HAMs induced greater Nrf2-mediated oxidative stress responses, demonstrating their distinct toxicity

137 Blocking the AFT4 stress response did not prevent suppression of TBXT and

138 The mechanisms described drive induction of stress response, DNA repair, or estrogen-induced genes,

139 ation and induction of endoplasmic reticulum stress responses during an extended period of ESHP.

140 ATF6 and IRE1/XBP1 pathways are separate ER stress-response effectors important to beta cell health

141 to play an important role in plant immunity, stress responses, environmental interactions, plant grow

142 The environmental stress response (ESR) is critical for cell survival.

143 terns have been reported: the "environmental stress response" (ESR) and the "common aneuploidy gene-e

144 iological constraints as key factors shaping stress response evolution, generating testable predictio

145 and functional relationships involving these stress response factors, many of which are activated in

146 3A2 knockdown induced an ATF4-CHOP-dependent stress response following rotenone exposure.

147 hing, leaf morphogenesis, floral transition, stress responses, fruit ripening, and root development.

148 ry fibroblasts and cancer cells expressing a stress-response gene module.

149 rstanding of the interplay of Hsps and other stress response genes in mycobacteria.

150 Consistent with a repressive role at stress response genes, genetic ablation of Mi-2beta did

151 induction, we found that the DNA damage and stress response genes, Growth arrest and DNA damage (GAD

152 ivo, decreased UPR-dependent induction of ER stress response genes.

153 stress conditions and triggers expression of stress response genes.

154 (COX-2), soluble epoxide hydrolase (sEH), ER stress-response genes including BiP, CHOP, and PDI in ma

155 lates the transcription of various oxidative stress-response genes.

156 ipt abundance of genes involved in (a)biotic stress response, gibberellic acid (GA) biosynthesis and

157 f reactive oxygen species and the subsequent stress response have been linked to the development of i

158 r-flight response induces the release of the stress response hormone norepinephrine to stimulate beta

159 nown to be involved in plant development and stress response, how specific DGK isoforms function in d

160 nse AntiViral (MISTRAV) and/or MItochondrial STress Response Hypoxia (MISTRH).

161 2 (NRF2), a major regulator of the oxidative stress response implicated in cell survival after ischem

162 ated activation of formin and a constitutive stress response in cultured cells, primary patient cells

163 Our study defines an antifolate stress response in E. coli and links its associated meta

164 We identified classical signatures of stress response in M. inflexa, including major changes i

165 es and biological mechanisms related to heat stress response in pigs and provide potential biomarkers

166 ne up-regulation is a common transcriptional stress response in RTECs to ischemia-, cisplatin-, and r

167 is elegans Msp1 homologue triggers an import stress response in the worm, which indicates a conserved

168 the protein kinase A (PKA)-mediated general stress response in yeast, which is required for resistan

169 , in the regulation of plant development and stress responses in Arabidopsis (Arabidopsis thaliana).

170 nding of the molecular mechanisms underlying stress responses in beta-cells promises to reveal new th

171 the c-Fos proto-oncogene as a mediator of ER stress responses in epithelial cells.

172 Spx is a major regulator of stress responses in Firmicutes.

173 te (SBR) has previously been used to measure stress responses in humans and may provide a non-invasiv

174 ctions of Polkappa could mediate its role in stress responses in mammalian cells.

175 pathway coordinates several inflammatory and stress responses in Mycobacterium tuberculosis (Mtb)-inf

176 al role for two Fe-S cluster genes in biotic stress responses in plants.

177 egulating gene expression, especially during stress responses in plants.

178 press NLR signaling to enable global osmotic stress responses in plants.

179 7) phosphorylation of ubiquitin functions in stress responses in Saccharomyces cerevisiae, including

180 describe how Sestrins mediate physiological stress responses in the context of nutritional and chemi

181 t here could provide insights into oxidative stress responses in the heart and avail the search for n

182 gen effectors that induce biotic and abiotic stress responses in the plant, as a first step towards e

183 und immunomodulatory effects of sustained ER stress responses in tumours.

184 e-2s (SnRK2s) are critical for plant abiotic stress responses, including abscisic acid (ABA) signalin

185 t development and it affects growth rate and stress responses, including susceptibility to plant RNA

186 NPY) is associated with buffering the neural stress response induced by corticotropin releasing facto

187 on, as a result of the endoplasmic reticulum stress response induced by high production of Igs, or by

188 The stress response is an adaptive means of maintaining phys

189 The glucocorticoid stress response is frequently used to indicate vertebrat

190 Although cellular stress response is important for maintaining function an

191 mbiotic anemones, suggesting that this early stress response is largely independent of the symbiosis.

192 size, while that of the sigma(54)-controlled stress response is regulated via the burst frequency.

193 high expression of the sigma(70)-controlled stress response is regulated via the burst size, while t

194 been linked to the activation of integrated stress response (ISR) by Gcn2.

195 antagonizes the activation of the integrated stress response (ISR) by phosphorylated translation init

196 The integrated stress response (ISR) converges on eIF2alpha phosphoryla

197 ds to sustained expression of the integrated stress response (ISR) effector activating transcription

198 Activation of the integrated stress response (ISR) or the ribosome-associated quality

199 profiling fully recapitulated the integrated stress response (ISR) pathway in yeast.

200 , GCN2-mediated activation of the integrated stress response (ISR) was apparent in the Gtpbp1(-/-) br

201 Here, we highlight how the integrated stress response (ISR), a central signaling network that

202 t FK506, causes activation of the integrated stress response (ISR), an event which is normally an acu

203 ha), the central component of the integrated stress response (ISR), impairs long-term memory formatio

204 n phosphorylated eIF2alpha in the integrated stress response (ISR), which is critical to normal cellu

205 Oylation is generally connected to different stress responses, it also fine-tunes light signalling by

206 tones by PARP-1 has been linked to genotoxic stress responses, its role in physiological processes an

207 Cellular stress response leading to down-regulation of transcript

208 ells to daunorubicin activated an integrated stress response-like transcriptional program to induce A

209 suggest that the modulation of mitochondrial stress responses may provide a method to ameliorate alco

210 nsmitter systems and are used to investigate stress response mechanisms.

211 red ANAC082, a recently identified ribosomal stress response mediator.

212 secondary to early life trauma, a more acute stress response, microbiome alterations, a genetic diath

213 scovered a vertebrate-specific MItochondrial STress Response (MISTR) circuit.

214 normally enhanced activation of the cellular stress response, monitored by PKR-mediated phosphorylati

215 Here, we report a mitochondrial stress response, named mitochondrial safeguard, that adj

216 Stress response networks enable fungi to adapt, grow, an

217 o the function of sphingolipids during plant stress responses, not only as structural components of b

218 motolerance, melanin and capsule production, stress responses, O-mannosylation, or retromer function.

219 ng the unfolded protein response, a cellular stress response of the endoplasmic reticulum, and remova

220 st that Myt TFs are essential restrictors of stress-response overactivity.

221 rmacologically or by suppression of other ER stress response pathway components led to an enhanced ov

222 TORC1 drives aging by augmenting a prominent stress response pathway in gut stem cells and identify p

223 ein response (UPR), an endoplasmic reticulum stress response pathway, has been implicated in the path

224 and finding evidence that they function in a stress response pathway.

225 encoding central regulators of C. neoformans stress response pathways and cell morphogenesis.

226 nterplay between oncogenic signalling and ER stress response pathways in the cancer cell and the prof

227 n of mitochondrial fusion activates multiple stress response pathways that enhance resistance to spec

228 rcadian clock networks, and phytohormone and stress response pathways that intersect with circadian c

229 tivation of lipid biosynthetic and oxidative-stress response pathways, including the antiferroptotic

230 however, few have defined roles in specific stress response pathways.

231 phenotype variability for developmental and stress response pathways.

232 blished stress assays and well-characterized stress response pathways.

233 nes resulted in the upregulation of multiple stress response pathways.

234 bed mutations in the C. elegans lifespan and stress-response pathways.

235 nd induces rhythms correlating with cellular stress-response pathways.

236 was involved in presentation of the blunted stress response phenotype by its interaction with the mo

237 uiring a substantial amount of energy, plant stress responses place a burden upon the cellular machin

238 s of toxic compounds, and that both of these stress responses predict endophyte species richness.

239 Surprisingly, the induced cellular stress response previously observed following FL exposur

240 scade to activate a specific transcriptional stress response program.

241 onally, MCPH1 is involved in the replication stress response, promoting telomere replication fork pro

242 emonstrated that increased expression of the stress response protein regulated in development and DNA

243 tion reveals the central role of chaperones, stress response proteins and transport pumps in cross-st

244 SINCs are enriched with stress response proteins, including nucleotide-binding l

245 he dorsal root ganglia, likely by activating stress-response proteins, including ATF3 and HO-1.

246 ipheral hormones and behaviors linked to the stress response, providing a potential therapeutic targe

247 hese responses arise via activation of major stress responses, providing direct support for the compe

248 small GTPase Ras1, as well as with divergent stress response regulators, including the cell wall kina

249 loci, including a number of development and stress response-related genes such as the RNA silencing

250 nisms of how phosphoinositides act in the ER stress response remain elusive.

251 iological functions of CDK8 in plant abiotic stress responses remain largely unexplored.

252 died, the genetic and molecular basis of HNT stress response remains unexplored.

253 e ABA and AsA signaling pathways interact in stress responses remains elusive.

254 se (GAPC), but its nuclear function in plant stress responses remains elusive.

255 mmune signaling, and glucocorticoid receptor/stress response showed enrichment among the suggestive G

256 The susceptibility of catalase and general stress response sigma factor mutants confirmed the syner

257 nsistent with their postulated role in acute stress responses.SIGNIFICANCE STATEMENT The C1 neurons a

258 ranslation to prolong lifespan and stimulate stress response such as the mitochondrial unfolded prote

259 n this study, we investigated one such brain stress response system, pituitary adenylate cyclase-acti

260 ion sensing hypothesis states that bacterial stress response systems can serve to detect ecological c

261 hat T6SS-derived cell damage activates these stress response systems.

262 Senescence is a stress response that can be induced by stimuli that incl

263 Cellular senescence is a stress response that elicits a permanent cell cycle arre

264 tions from FSGS mouse models showed an early stress response that includes perturbations of metabolic

265 ure to real or imagined threats that trigger stress responses that affect the body and brain, particu

266 hat are involved in control of metabolic and stress responses that either originate from lysosomes or

267 Unfortunately, stress responses that mitigate disturbances in proteosta

268 D(H), and is a direct regulator of oxidative stress response through its NADPH 2' phosphatase activit

269 program represents repurposing of a generic stress response to gain considerable gain-of-fitness ass

270 rade signaling upregulates the mitochondrial stress response to maintain mitochondrial integrity.

271 egulation of genes involved in apoptosis and stress response to microbiomes.

272 henotypes and underscores the ability of the stress response to mitigate TBI-induced brain degenerati

273 nctional properties in global regulation and stress response to study specific disease conditions and

274 Our work shows that bacteria use stress responses to detect and respond to competition in

275 ple experiments to identify commonalities in stress responses to different conditions.

276 ave roles in cellular processes ranging from stress responses to regulation of gene expression.

277 ts, which engage in metabolic regulation and stress responses to support cellular adaptation to a cha

278 nt restores systemic ROS signaling, systemic stress-response transcript expression, and SAA to a loca

279 f PP-InsPs influence the ESR through general stress response transcription factors Msn2/4.

280 cambium data revealed evolutionary conserved stress-response transcription factors that may intimatel

281 OsHOX24 mediates regulation of desiccation stress response via complex regulatory network as indica

282 s to regulate plant development, growth, and stress responses via a well-studied signaling pathway.

283 wever, loss of Hel2 triggered the integrated stress response, via phosphorylation of eIF2alpha, thus

284 The ER stress response was found to be constitutively induced i

285 Interestingly, S aureus-induced ER stress response was found to be dependent on Toll-like r

286 ry to the reproductive value hypothesis, the stress response was not lower in populations engaging in

287 Moreover, while evidence for a cellular stress response was present, we also observed constituti

288 Importantly, activation of the integrated stress response was reversed in airway T(RM) cells place

289 wever, PI(3)P function during the Plasmodium stress response was unknown.

290 mental unpredictability hypothesis, stronger stress responses were seen in more unpredictable environ

291 at the defects of the bon mutants in osmotic stress responses were suppressed by mutations in the NLR

292 ce-exposed lipoprotein that triggers the Rcs stress response when damage occurs in the outer membrane

293 tein translation and increase the integrated stress response, whereas MLIII mice upregulate the prote

294 ption program called the mitoprotein-induced stress response, which activates the proteasome system.

295 e connection between gut microbiota and host stress response, which can be further investigated in th

296 throid 2-related factor 2-mediated oxidative stress response, which collectively contributed to enhan

297 ignificantly increased during the integrated stress response, which occurs in eukaryotic cells in res

298 ed to As leads to endoplasmic reticulum (ER) stress response, which, if not relieved, results in cell

299 ontrolled initiation of the unfolded protein stress response, with single-cell analysis of primary bo

300 MAPK causes NF-kappaB-dependent inflammatory stress response within the BM, leading to significant HS