ライフサイエンスコーパス: striatum

1 genes (Ccl5 and Cxcl10) are increased in HD striatum.

2 and abundance of D1 and D2 receptors in the striatum.

3 sion selectively in ventral, but not dorsal, striatum.

4 well as cortical and thalamic inputs to the striatum.

5 glycans in SN which were not detected in the striatum.

6 lutamate as a second neurotransmitter in the striatum.

7 ormation, involving the left lateral ventral striatum.

8 rofiling in the nucleus accumbens and dorsal striatum.

9 r functional coupling of the hippocampus and striatum.

10 bserved to be twice larger than reported for striatum.

11 tromedial prefrontal cortex and left ventral striatum.

12 ated and sequenced by activity in the dorsal striatum.

13 ergic indirect and direct pathway within the striatum.

14 ated axons and axon terminals in the primate striatum.

15 oked dopamine release in the ventral lateral striatum.

16 nucleus, the opposite was found in the mouse striatum.

17 n network parameters are appropriate for the striatum.

18 a nigra and radiotracer studies of the human striatum.

19 to the actions of benzodiazepines within the striatum.

20 ctivation of microglia and astrocytes in the striatum.

21 cortex are the major source of input to the striatum.

22 nd putamen, brain regions which comprise the striatum.

23 s (14.3 +/- 2.6%) in the matrix of the mouse striatum.

24 omedial striatum but not in the dorsolateral striatum.

25 d preferentially recorded in the dorsomedial striatum.

26 ts localised to different sub-regions of the striatum.

27 n area involved in all these diseases is the striatum.

28 to the DA depletion areas in the dorsomedial striatum.

29 rminals from female ventral, but not dorsal, striatum.

30 ernalization in both male and female ventral striatum.

31 rface expression in either dorsal or ventral striatum.

32 stimulus-evoked dopamine (DA) release in the striatum.

33 of activity in striosomes and matrix of the striatum.

34 rons are the main neuronal population in the striatum.

35 cits and impaired synaptic plasticity in the striatum.

36 med fibrils treated microglia into the mouse striatum.

37 rtex, lateral prefrontal cortex and anterior striatum.

38 ylase (TH) in tissue sections of adult mouse striatum.

39 triatum (VLS), but not in the ventral medial striatum.

40 infarct size and angiogenic findings in the striatum.

41 ractions in medium spiny neurons of HD mouse striatum.

42 the visual hyperpallium, and to the lateral striatum.

43 (2.15 [0.56] vs 2.48 [0.52]; p<0.0001), and striatum (2.56 [0.57] vs 2.87 [0.55]; p<0.0001).

44 as driven entirely by DeltaBP(ND) in ventral striatum (-34 +/- 14% in CHR, -20 +/- 12% in HC; p = 0.0

45 he tyrosine hydroxylase protein level in the striatum (~60%), the DA (~22%), and 3,4-dihydroxyphenyla

46 nabis, disrupts autophagy selectively in the striatum, a brain area that controls motor behavior, bot

47 turbed value-modulated neural signals within striatum, a central node in feedback-based reinforcement

48 icipation across a cortico-striatal circuit (striatum, ACC, insula).

49 al magnetic resonance imaging (fMRI) ventral striatum activation during reward anticipation (primary

50 ival motor neuron pre-mRNA in the cortex and striatum after intracerebroventricular injection.

51 patch) and matrix compartments of the dorsal striatum, allowing compartmentalized control of discrete

52 Higher PiB-PET measures in the subcortex (striatum, amygdala, and thalamus), but not in the cortex

53 gramming in circadian gene expression in the striatum, an area involved in psychomotor and rewarding

54 Aberrant dopamine function in the dorsal striatum and aberrant intrinsic functional connectivity

55 are consistent with findings in the ventral striatum and amygdala and show that this monosynapticall

56 human embryonic stem cells (hESCs) into the striatum and assessed their survival, growth, and functi

57 tures are hypomyelination and atrophy of the striatum and cerebellum.

58 function and social/language regions of the striatum and connected to prefrontal-projecting cerebell

59 6 CAG repeat alleles and 3 age points in the striatum and cortex of Hdh mice.

60 neuroinflammation, mainly in the ipsilateral striatum and distant regions with synaptic links to the

61 Ventral striatum and dopaminergic midbrain neurons form a larger

62 s (dopamine, opioid peptides) in the ventral striatum and from the between-system recruitment of brai

63 and other axons at the junction between the striatum and globus pallidus.

64 regions, AAV2.retro transduced cells in the striatum and in dozens of cortical and subcortical regio

65 risk group interactions were observed in the striatum and OFC.

66 utionary conserved brain structures like the striatum and optic tectum, which receive ascending visua

67 r stimulants increase dopamine levels in the striatum and promote locomotion; however, their effects

68 eceptor that is selectively expressed in the striatum and regulates various brain functions through a

69 Differences in the striatum and right cerebellum were also identified betwe

70 actosylation (di-, tri-, and tetra-) between striatum and SN N-glycans with the detection of phosphor

71 s of relative abundances of N-glycans in the striatum and SN of rodent brains, serving as a foundatio

72 The total N-glycomes from the striatum and SN were characterized using database mining

73 include isolation of N-glycans from the rat striatum and SN; reproducibility, resolution, and relati

74 ing of dense dopaminergic axons in the mouse striatum and sparse noradrenergic axons in the mouse cor

75 ic resolution of N-glycans isolated from the striatum and substantia nigra (SN) can give an insight i

76 r, human alpha-synuclein was detected in the striatum and superior colliculus (SC).

77 Finally, the striatum and thalamus showed a wide range of synapse den

78 ts in decreased dopamine (DA) release in the striatum and thus impaired motor functions.

79 t subpopulations of GABAergic neurons in the striatum and to assess the outcome of deep therapeutic h

80 es mapped to variability in responses of the striatum and ventromedial prefrontal cortex.

81 cortical regions (including the thalamus and striatum) and the inter-network integration between the

82 structured options depends on the neocortex, striatum, and amygdala.

83 brain regions of male and female mice: GPe, striatum, and cortex.

84 anges in dopamine receptor occupation in the striatum, and explains why dopamine ramps are an effecti

85 sensitive markers decreased in the thalamus, striatum, and globus pallidus, while iron-sensitive mark

86 aired operation of GABA signaling within the striatum, and hyper-excitability of cortical sensorimoto

87 take in the cerebellum, cortex, hippocampus, striatum, and hypothalamus of lipopolysaccharide-treated

88 e determine that regions of the hippocampus, striatum, and midbrain are most influential in driving t

89 s and astrocytes in supporting DA release in striatum, and reveal a maladaptive plasticity in early p

90 are reduced in the medial prefrontal cortex, striatum, and thalamus in schizophrenia.

91 lower extremity) and pulvinar thalamus, and striatum; and expanded in the motor thalamus and striatu

92 nvector centrality positively in the ventral striatum, anterior cingulate and somatosensory cortex, a

93 ion to the reinforced object category in the striatum, anterior cingulate cortex, amygdala, occipitot

94 function of the striosome compartment of the striatum are critical for this type of learning.

95 Dopamine levels in the ventral striatum are elevated following exposure to stress.

96 n tomography (PET), we identified the dorsal striatum as the brain area most altered in DIO-susceptib

97 ion carriers were the bilateral thalamus and striatum as well as a predominantly right-sided network

98 eased by heroin use in the post-mortem human striatum, as well as in rats trained to self-administer

99 Importantly, overexpression of NLK in the striatum attenuates brain atrophy, preserves striatal DA

100 ons all can affect brain structure, with the striatum being particularly sensitive to HIV effects.

101 Reelin+ cells showed no staining in the striatum besides subventricular zone.

102 hubs of the brain reward system (the ventral striatum), better reward learning in the Probabilistic R

103 mpus, central amygdala, piriform cortex, and striatum, brain regions associated with learning and syn

104 tion in brain regions (orbitofrontal cortex, striatum, brainstem, and thalamus) that lie in the traje

105 r local effects on dopamine signaling in the striatum but not in extrastriatal areas.

106 reduced dopamine release in the dorsomedial striatum but not in the dorsolateral striatum.

107 forcement-related prediction errors (ventral striatum), but also aversive processing (insular cortex

108 with adult offspring SST mRNA in cortex and striatum, but not hippocampus.

109 Glutamatergic innervation of the striatum by the cortex and thalamus is a critical determ

110 in scRNA-seq data and found that SPNs in the striatum can be classified into four major discrete type

111 cific ways, the hippocampus and dorsolateral striatum can transcend their attributed roles in informa

112 Different afferents to the striatum can trigger dopamine signals, but their release

113 tal, and average SBRs and z scores for whole striatum, caudate, putamen, anterior putamen, and poster

114 astrocytes, and are enriched in dorsolateral striatum compared to accumbens core.

115 ions using chemogenetic inhibition of dorsal striatum D1-medium spiny neurons (D1-MSNs) in both juven

116 c atrophy and dendritic spine loss in dorsal striatum D1-MSNs from mice with repetitive behavior.

117 puts to dorsal striatum mediates many dorsal striatum-dependent behaviors and disruption of LTD influ

118 lation or the implantation of eMSCs into the striatum did not show such ameliorative effects.

119 sks, we demonstrate that phasic dorsolateral striatum (DLS) activity occurring at the onset of a lear

120 ls disrupted action encoding in dorsolateral striatum (DLS) associated with altered habit learning.

121 n made to understand "what" the dorsolateral striatum (DLS) does for habitual behavior, and our resea

122 ating goal-directed actions and dorsolateral striatum (DLS) mediating habitual actions.

123 from M2 cortex terminals in the dorsolateral striatum (DLS) was undetectable in HD mice and striatal

124 learning," associated with the dorsolateral striatum (DLS), decisions are anchored to an egocentric

125 mpus (DH)-dependent spatial and dorsolateral striatum (DLS)-dependent cued-response memories, often i

126 rojection neuron (dSPN)] in the dorsolateral striatum (DLS).

127 FC), basolateral amygdala (BLA), dorsomedial striatum (DMS) and olfactory piriform cortex (PIR).

128 The role of the dorsomedial striatum (DMS) in regulating goal-directed reward-seekin

129 involved in action control, with dorsomedial striatum (DMS) mediating goal-directed actions and dorso

130 Fyn kinase in the dorsomedial striatum (DMS) of rodents plays a central role in mechan

131 ream brain regions such as the dorsal medial striatum (DMS) that encode action plans necessary for ta

132 tico-thalamic iFC, i.e. aberrant associative striatum dopamine is associated with aberrant iFC betwee

133 ed system, patients had reduced sensorimotor striatum dopamine synthesis capacity, which correlated p

134 work and thalamus, and aberrant sensorimotor striatum dopamine with aberrant iFC between the auditory

135 nucleus accumbens) and nigrostriatal (dorsal striatum) dopamine pathways using fast-scan cyclic volta

136 ng dopamine D2 receptors (D2R) in the dorsal striatum (DS) and the nucleus accumbens (Acb) jointly bu

137 tex (OFC), ventral striatum (VS), and dorsal striatum (DS), while macaques performed a rule-based dec

138 declined in mPFC but was elevated in dorsal striatum (DS).

139 neurons projecting to different parts of the striatum encode errors in predictions made by the corres

140 ociated with the age-dependent expression of striatum-enriched HspBP1, a chaperone inhibitory protein

141 clusion, cortical and midbrain inputs to the striatum evoke DA signals with unique spatial and pharma

142 time equally well; however, the dynamics in striatum exhibited a higher degree of sequentiality.

143 Results: Tracer uptake was highest in the striatum, followed by neocortical regions and white matt

144 The prefrontal cortex and striatum form a recurrent network whose spiking activity

145 hort and found similar results in the dorsal striatum from cocaine self-administering mice.

146 H(1), H(2), and H(3) histamine receptors in striatum from the first postnatal week onwards, with pro

147 egeneration between cortex, corpus callosum, striatum, globus pallidus, and thalamus after cerebral i

148 ricted to D3 selective brain regions (limbic striatum, globus pallidus, and ventral pallidum (9-14%;

149 The striosome compartment within the dorsal striatum has been implicated in reinforcement learning a

150 al lateral prefrontal cortex, and the dorsal striatum, has minimal connectivity with the hypothalamus

151 entral medial prefrontal cortex, and ventral striatum, has substantial connectivity with the hypothal

152 e ventral tegmental area and projects to the striatum-has been shown to be involved in the expression

153 ter CD36 mRNA expression than females in the striatum, hippocampus, and midbrain.

154 ) 5 in regional brain circuitries, including striatum, hippocampus, and raphe nucleus.

155 bunit-rich brain regions such as the cortex, striatum, hypothalamus, and hippocampus.

156 Baseline surface area expansions within the striatum (i.e. motor caudate) predicted better lower ext

157 oline release from midbrain terminals in the striatum impairs the association of contingencies and th

158 eurotransmission, and symptomatically in the striatum, implicating cell survival (e.g. Hipk4) intertw

159 ng inhibitory-related deficits in cortex and striatum in adult offspring from MIA.

160 ions are misguided and fail to innervate the striatum in both constitutive and striatal-specific Nolz

161 es and age-dependent HTT accumulation in the striatum in different KI mice.

162 A2A+ (indirect) neurons in the ventrolateral striatum in head-fixed mice on a fixed time reinforcemen

163 ment of chromatin accessibility of the human striatum in heroin users and matched controls.

164 has shed new light on the role of the dorsal striatum in learned movement sequences and the effort re

165 ulation dynamics between premotor cortex and striatum in mice performing a two-interval timing task.

166 accumbens (NAc) core and dorsolateral (DLS) striatum in Npas2 mutant females after dark phase self-a

167 our data demonstrate the involvement of the striatum in orchestrating dopaminergic circuitry formati

168 is the root cause of dopamine deficit in the striatum in Parkinson's disease.

169 atum; and expanded in the motor thalamus and striatum in patients compared to controls over 2-years.

170 ectivity in the superior parietal cortex and striatum in their global network.

171 OE alters transcriptional homeostasis in the striatum, including specific alterations in Drd1a versus

172 selective areas) and hippocampus and ventral striatum increased as a function of RPE value (during le

173 med in temporal proximity, while the lateral striatum integrates memories formed in the same space.

174 Moreover, we simulate a subset of the striatum involving 10,000 neurons, with input from corte

175 The dorsal striatum is a brain region involved in action control, w

176 g in the striatum.SIGNIFICANCE STATEMENT The striatum is a structure that is linked to volitional mov

177 Notably, re-innervation of striatum is accompanied by restoration of dopamine level

178 erated but its selective accumulation in the striatum is associated with the age-dependent expression

179 The ventral striatum is believed to encode the subjective value of c

180 The striatum is critical for controlling motor output.

181 ase of DA from these neurons into the dorsal striatum is crucial for regulating movement and their lo

182 ggests that function and connectivity of the striatum is disrupted in schizophrenia(1-5).

183 extent the functional specialization of the striatum is due to the molecular specialization of SPN s

184 The dorsal striatum is important for motor control.

185 The mammalian striatum is involved in many complex behaviors and yet i

186 on-related topographical organization of the striatum is preserved in all BG output nuclei.

187 dopamine release from axon terminals in the striatum is that it is rapidly modulated by local regula

188 The striatum is the main input structure of the basal gangli

189 The striatum is the most vulnerable region, although all bra

190 ously unknown source of acetylcholine in the striatum, is a major contributor to cholinergic transmis

191 Their main input structure, striatum, is central to this process.

192 This differs from the striatum, locus coeruleus, and spinal cord, where multip

193 ggest that DAT traffics between midbrain and striatum, mainly by lateral diffusion in the plasma memb

194 d motor responses in the dopamine-denervated striatum may prompt the development of new therapeutic p

195 y networks, the hippocampus and dorsolateral striatum, may accomplish such a goal.

196 measure dopamine binding across the ventral striatum (medial accumbens shell, accumbens core, latera

197 plasticity at glutamatergic inputs to dorsal striatum mediates many dorsal striatum-dependent behavio

198 regulation of EAAT2 expression in the dorsal striatum, mice were trained on an instrumental task.

199 tively plausible that such disruption in the striatum-modulated tonic inhibition of the thalamus from

200 l connectivity within a hippocampus-thalamus-striatum network decreased only in responders after two

201 ggested that, perhaps especially, within the striatum, neuronal populations exist in continua, with r

202 ng DA axonal tract formation and renders the striatum non-permissive for dopaminergic and other foreb

203 utamate neurons into the substantia nigra or striatum of a mouse PD model and found extensive graft i

204 he cause of excessive neuronal demise in the striatum of Abeta + ET1 rats.

205 pecific deletion of VAChT in the dorsomedial striatum of adult mice was sufficient to phenocopy malad

206 ron axons and branching processes within the striatum of adult mice.

207 In the ventral striatum of CHL1-deficient mice, levels of phosphorylate

208 In the dorsal striatum of CHL1-deficient mice, lower levels of DRD2 an

209 medium spiny neurons (iMSNs) in the ventral striatum of D2R knockout mice, this mutant restored basa

210 (2) SSTR2 mRNA reductions in the cortex and striatum of GD19, but not GD10, MIA; (3) no alterations

211 and reduced glutamate/glutamine ratio in the striatum of HD mice.

212 ng an altered dopaminergic regulation in the striatum of Het mice.

213 overexpress Nurr1 or GFP in the parkinsonian striatum of LID-resistant Lewis or LID-prone Fischer-344

214 NBCn1 downregulation in the hippocampus and striatum of mice and humans.

215 and multiunit activity from the dorsomedial striatum of mice as they spontaneously explored an arena

216 ogenetic activation of neurons in the dorsal striatum of mice during a visual spatial attention task

217 piny projection neurons (SPNs) in the dorsal striatum of mice following acute exposure to cocaine.

218 lar zone (SVZ) of the lateral ventricles and striatum of mice with genetic deletion (D1(-/-) , D2(-/-

219 ded and examined multi-unit signals from the striatum of PD and dystonic patients undergoing deep bra

220 identified to be ectopically induced in the striatum of rodents expressing l-DOPA-induced dyskinesia

221 These include the striatum of the basal ganglia, the dorsolateral prefront

222 A proteomic and kinomic screen of the striatum of xCT(-/-) mice revealed decreased expression

223 in two ASD-related brain regions, cortex and striatum of young and adult InsG3680(+/+) mice (a human

224 (11)C]ABP688 BP(ND) values were lower in the striatum, OFC, and insula.

225 ted with alpha-synuclein aggregates into the striatum or substantia nigra.

226 In cultures of striatum or ventral midbrain, CHL1 was also closely asso

227 s involved in affect and reward, such as the striatum, orbitofrontal cortex, and amygdala.

228 thin the bilateral mid-insula as well as the striatum, orbitofrontal cortex, and bilateral amygdala.

229 In most areas investigated, notably in the striatum/pallidum, amygdaloid nuclei and in the hippocam

230 The posterior dorsomedial striatum (pDMS) is necessary for goal-directed action; h

231 GNIFICANCE STATEMENT Dopamine signals in the striatum play a critical role in basal ganglia function,

232 Acetylcholine in the striatum plays a pivotal role in such adaptation, and it

233 of dopamine (DA) synthesis capacity, in the striatum predictive of conversion to schizophrenia.

234 In the dorsal striatum, protein restriction at adulthood has no impact

235 es, as well as the hippocampal formation and striatum, provide a plethora of examples of vector codin

236 The dorsolateral striatum provides the basis for habits that are assessed

237 onism, but not D1R antagonism, in the dorsal striatum: raclopride increased errors in the intermediat

238 th seed-based connectivity analysis with the striatum recapitulated the cingulate-striatum relationsh

239 ally the caudate nucleus 'head' (CDh) of the striatum, receive indirect anatomical connections from t

240 NA injections in HD mouse striatum reduce mutant HTT protein aggregates, a biomark

241 ith the striatum recapitulated the cingulate-striatum relationship observed in humans.

242 In vmPFC and ventral striatum, representations of prediction error also depen

243 mapped to activity in the ventral and dorsal striatum, respectively.

244 vity to angry facial expressions and ventral striatum responsivity to monetary rewards.

245 ongly upregulated in the dopamine-denervated striatum, resulting in a synergistic activation of PLC s

246 Retrograde tracing from the dorsolateral striatum reveals that both layer II/III and V neurons in

247 rmalities in left supramarginal gyrus, right striatum, right inferior frontal gyrus, left thalamus, b

248 polyQ proteins in Huntington's disease mouse striatum sequester TOLLIP away from STING, leading to re

249 expression in the lateral part of the dorsal striatum shapes behavior, thus providing novel mechanist

250 Local field potential recordings in rodent striatum show dopamine- and reward-dependent transitions

251 t rather in circuits involving the olfactory striatum.SIGNIFICANCE STATEMENT Rodents are olfactory sp

252 entral component of movement encoding in the striatum.SIGNIFICANCE STATEMENT The striatum is a struct

253 The principal neurons of the striatum, spiny projection neurons of the direct (dSPN)

254 a group of subcortical structures including striatum, substantia nigra, basal forebrain (BF), pedunc

255 The dorsomedial and dorsolateral striatum support goal-directed and habitual action strat

256 hanisms by which motor cortex, thalamus, and striatum support motor learning.

257 In contrast, the lateral striatum supported both types of memories if they were f

258 le gradients are topographically mirrored in striatum, thalamus, and cerebellum.

259 mic D2- to D1-SPN transmodulation across the striatum that is necessary for updating previous goal-di

260 al anterior cingulate cortex and the ventral striatum that negatively correlated with increased nicot

261 HD pathology is most prominent in the striatum, the central hub of the basal ganglia.

262 Furthermore the striatum, the DLPFC, the insula and the vmPFC appeared t

263 ies show decreased dopamine signaling in the striatum, the finding of increased NM-MRI signal in the

264 s of synaptic mitochondria isolated from the striatum, the location of nigrostriatal pathway nerve te

265 or limb of the internal capsule, the ventral striatum, the subthalamic nucleus, and a midbrain target

266 thought to depend on dopamine signals in the striatum, the way the circuits that mediate goal-directe

267 it induces noticeable damage to the brain's striatum, thereby affecting motor, psychiatric, and cogn

268 How ethanol targets dorsolateral striatum to drive compulsive consumption is poorly under

269 uses fast spiking interneurons (FSIs) in the striatum to train striatal projection neurons to gate re

270 Striatum-to-background ratios (SBRs) generated by DaTQUA

271 d infralimbic (IL) cortical afferents to the striatum triggers an increase in extracellular DA concen

272 n of cortical glutamatergic afferents to the striatum triggers dopamine signals both in vivo and in v

273 ay be more appropriately termed the "tubular striatum" (TuS), is a neural system in which sensory inf

274 eveals that the hippocampus and dorsolateral striatum use distinct and complementary principles to in

275 esent a nearly full-scale model of the mouse striatum using available data on synaptic connectivity,

276 de, of stimulus responses across much of the striatum, via quantifiable postsynaptic effects that var

277 The ventrolateral subfield of the striatum (VLS) is the orofacial projection field of the

278 oked dopamine release in the ventral lateral striatum (VLS), but not in the ventral medial striatum.

279 gned RPEs (SRPEs) are encoded in the ventral striatum (VS), and crucially, that SRPE VS activity is r

280 ing, the orbitofrontal cortex (OFC), ventral striatum (VS), and dorsal striatum (DS), while macaques

281 bserve that SRPEs are encoded in the ventral striatum (VS).

282 PFC, basolateral amygdala (BLA), and ventral striatum (VS).

283 In contrast, activity in ventral striatum was associated with subjects' global SPEs irres

284 Axonal pathfinding toward the dorsal striatum was determined by the identity of the grafted n

285 Dysregulation of HD-related pathways in striatum was exacerbated by JQ1 in R6/2 mice, but not in

286 d the potential role of GluD1 in the primate striatum, we compared the cellular and subcellular local

287 perimental perturbations of relevance to the striatum, we discovered that striatal astrocytes mount c

288 eft and right SBRs for caudate, putamen, and striatum were evaluated with the manual method.

289 f c-Fos expression and dopamine level in the striatum were greater in Het mice than in WT controls, s

290 Following the trial, cortex and striatum were isolated and subjected to mRNA-seq and ChI

291 ompanied by enhanced activity in the ventral striatum when curiosity or hunger was elicited, which ex

292 rtex, anterior cingulate cortex and anterior striatum when outcomes were processed.

293 was elicited, which extends into the dorsal striatum when participants made a decision.

294 Axons of dopaminergic neurons innervate the striatum where they contribute to movement and reinforce

295 tocin to specific brain regions, such as the striatum, where oxytocin acts to impact motivated behavi

296 o found in the prefrontal cortex and ventral striatum which, although of smaller amplitude, were cohe

297 tuberculum, including in projection cells to striatum, which represents a striking parallel to amniot

298 ntration in these brain areas, including the striatum, which shapes an abnormal memory trace of drug

299 lutamate as a second neurotransmitter in the striatum, while only few adult substantia nigra DA neuro

300 ontal regions with risk for BD, and in right striatum with risk for MDD.