ライフサイエンスコーパス: structural characterization

1 ght the potential for new approaches for ion structural characterization.

2 imes dynamic, and thus difficult targets for structural characterization.

3 develop new methods and strategies for their structural characterization.

4 rate reduction, for detailed biophysical and structural characterization.

5 robactin complex has eluded crystallographic structural characterization.

6 (FcRn) binding correlated very well with the structural characterization.

7 tance of glycosyltransferase (GT) enzymes to structural characterization.

8 FPOP) has become a valuable tool for protein structural characterization.

9 cal formulas while also enabling preliminary structural characterization.

10 RNA molecules is outpacing three-dimensional structural characterization.

11 at target RNA requires their high-resolution structural characterization.

12 ceptor that has thus far eluded experimental structural characterization.

13 ion and tandem mass spectrometry (MS/MS) for structural characterization.

14 ded in vitro and purified for functional and structural characterization.

15 zed in the pretriggered state 1 for possible structural characterization.

16 icular challenge in terms of sensitivity and structural characterization.

17 n of disulfide bonds is revealed by material/structural characterizations.

18 Rs) and guide drug design via microisolation-structural characterization and ALIS capabilities.

19 In situ magneto-structural characterization and atomic-scale tracking of

20 oscopy (TEM) has provided a route to analyze structural characterization and chemical evolution with

21 Structural characterization and computational studies re

22 Careful structural characterization and defect characterization

23 The structural characterization and electrochemical sensor f

24 lycoprotein (Env) trimer has facilitated its structural characterization and guided Env immunogen des

25 ated using a conventional approach and their structural characterization and localization at a latera

26 Together with additional structural characterization and microscopy data, these r

27 Structural characterization and mutagenesis of SznF reve

28 mural cells along the vascular tree for both structural characterization and physiological manipulati

29 the metastable state-1 Env conformation for structural characterization and presentation to the immu

30 , and EPR measurements were supported by the structural characterization and quantum chemical analysi

31 hy-tandem mass spectrometry (RPLC-MS/MS) for structural characterization and relative quantification

32 and highlight the critical need for precise structural characterization and systematic assessment of

33 he obtained BCNCs were analyzed based on the structural characterization and the properties of the na

34 Atomic structural characterizations and density functional theo

35 Here we report synthesis, structural characterization, and biological activity of

36 onal, pure hABHD6 will aid in the downstream structural characterization, and development of potent,

37 We report the synthesis, structural characterization, and reactivity of a series

38 le myosin, as evidenced by a biochemical and structural characterization, and to directly monitor sub

39 Advanced synchrotron techniques, post structural characterizations, and density functional the

40 fficient quality for further biochemical and structural characterization, as well as for use in consu

41 the cleavage or formation of chemical bonds, structural characterization at the atomic level is most

42 extreme reactivity presents an impediment to structural characterization, but their biological import

43 Structural characterization by cocrystallization showed

44 unit cells per edge, on average-has impeded structural characterization by conventional means.

45 Structural characterization by CryoEM reveals a lipid-in

46 In this study, structural characterization by electron-induced dissocia

47 Structural characterization by single-crystal X-ray diff

48 methyl-xanthene; Dipp=2,6-diisopropylphenyl) structural characterization by X-ray crystallography rev

49 , and its flexibility has thus far prevented structural characterization by X-ray crystallography.

50 ridged dicopper complex) has allowed for its structural characterization by X-ray diffraction.

51 Detailed structural characterizations by Raman spectroscopy and h

52 Experimental structural characterization can detail the 'ground truth

53 terogeneous conformations, which makes their structural characterization challenging.

54 The detailed structural characterization, comparison of properties, a

55 Detailed structural characterizations confirm the presence of Cu(

56 Our structural characterization defines the order of the elu

57 Biochemical and structural characterization demonstrates that the AcCS s

58 Herein, our biophysical and structural characterization demonstrates that, with the

59 Structural characterization disclosed how the newly iden

60 IM-MS) has become a powerful tool for glycan structural characterization due to its ability to separa

61 trometry (IM-MS) is a powerful technique for structural characterization, e.g., sizing and conformati

62 Proton NMR spectra are indispensable for structural characterization even in conjunction with 2D

63 ombining quantitative three-dimensional (3D) structural characterization, four-dimensional (4D) mecha

64 In-depth structural characterization from a suite of biophysical

65 A deep structural characterization, if possible with large-mola

66 NMR-based structural characterization implies that the lithium pin

67 nd may benefit other areas of pharmaceutical structural characterization including impurity profiling

68 Structural characterization, IR spectroscopy, and DFT ca

69 e to flexible nature of the molecules, their structural characterization is challenging.

70 The structural characterization is confirmed by X-ray diffra

71 a correlation of the QCM-D results with the structural characterization it is possible to infer that

72 manner via SCF(betaTrCP1) complex; however, structural characterization, mode of action based on seq

73 han 20 such potential substrates, as well as structural characterization of 12 resulting unknown prod

74 , we report the biochemical, functional, and structural characterization of a 130-amino-acid protein,

75 and is exemplified here by the synthesis and structural characterization of a [13]rotaxane, containin

76 This study focuses on the structural characterization of a biosensor for NE activi

77 r study presents the first atomic resolution structural characterization of a client protein bound to

78 zenes and Cp*RuCl was studied and led to the structural characterization of a Cp*RuCl(eta(2)-alkyne)

79 Here we report the structural characterization of a diamond composite hiera

80 Here, we report the structural characterization of a Mo(2)CT(x):Co phase (wh

81 The latter represents the first structural characterization of a monohydrido bridged iso

82 Structural characterization of a neutralizing antibody (

83 It is illustrated through the structural characterization of a new highly air-sensitiv

84 report on the evolutionary, biological, and structural characterization of a novel bat adenovirus (B

85 Cp''3 is also reported, comprising the first structural characterization of a Pu-C bond.

86 re, we describe the synthesis and functional/structural characterization of a series of reversible ti

87 Here we report the isolation and structural characterization of a simple coordination com

88 e, mechanistic cross-linking facilitates the structural characterization of a stable hexameric comple

89 This work constitutes the most extensive structural characterization of a viral lncRNA and intera

90 ed heterogeneous catalysts requires detailed structural characterization of active sites, an essentia

91 what has been learned from this atomic-level structural characterization of affinity maturation in HI

92 modeling provided a first, to our knowledge, structural characterization of an entire NOX enzyme.

93 ding the isolation of key intermediates, the structural characterization of an iron-metallacycle, and

94 otential of polarized Raman spectroscopy for structural characterization of anisotropic biological sp

95 ly available for B19, and there is a lack of structural characterization of any B19 epitopes.

96 Here, we present a kinetic and structural characterization of AsFMO that suggests a pos

97 Herein, we report on the detailed structural characterization of atmospherically relevant

98 By providing structural characterization of authentic C-H functionali

99 roviding unprecedented opportunities for the structural characterization of biological macromolecules

100 metry are two well-established tools for the structural characterization of biomolecular complexes.

101 Computational modeling is essential for structural characterization of biomolecular mechanisms a

102 ficiency of glycolipids but also facilitated structural characterization of both moieties.

103 Here we report the detailed biochemical and structural characterization of Bsp5, an imino acid reduc

104 Here we report the isolation and structural characterization of CAP257-RH1, an N276 glyca

105 Analysis of the elementary steps enabled structural characterization of catalytically relevant in

106 A recent structural characterization of cell walls from monocot s

107 top-down analysis an indispensable tool for structural characterization of complex biomolecules.

108 Complete structural characterization of complex lipids, such as g

109 Advances in the structural characterization of components of the human R

110 significantly expand the use of DEER for the structural characterization of conformational changes in

111 dissociation mass spectrometry (UVPD-MS) for structural characterization of cyclopropane rings in bac

112 Here, we report the biochemical and structural characterization of different mutant polymera

113 ptomic, and metabolomics analyses, including structural characterization of differentially expressed

114 Here, we present the synthesis and structural characterization of dinitrohydrazone (hydz) f

115 The structural characterization of diterpenoids accumulating

116 ion mobility and tandem MS analysis for the structural characterization of DOM.

117 Recent advances in the structural characterization of dopamine and serotonin tr

118 Full spectroscopic and structural characterization of each derivative establish

119 Structural characterization of EcBcsG(DeltaN) revealed t

120 red enzymes.Significant challenges exist for structural characterization of enzymes responsible for b

121 al enthalpy calculations in conjunction with structural characterization of ethylene binding in Co2(m

122 g the in-depth biochemical, biophysical, and structural characterization of FadD32, we investigated i

123 Structural characterization of FluA-20 with H1 and H3 he

124 re an in-depth biochemical, biophysical, and structural characterization of four FadD32 orthologs, in

125 In this study, we present the structural characterization of full-length IRF4.

126 relevance to cell function and pathogenesis, structural characterization of full-length tandem-repeat

127 trap mass spectrometer as another option for structural characterization of GAGs.

128 n is an essential technique for the detailed structural characterization of glycans by mass spectrome

129 s drastically raised the demand for detailed structural characterization of glycans.

130 The need for detailed structural characterization of glycerophospholipids (GPL

131 ectrometry have made it a preferred tool for structural characterization of glycerophospholipids.

132 LC-MS) is arguably the gold-standard for the structural characterization of glycoconjugates, especial

133 fer dissociation (ETD) alone is used for the structural characterization of glycopeptides.

134 To address the dearth of atomic-level structural characterization of heterochiral helix pairin

135 pects of applying physisorption for the pore structural characterization of hierarchical materials su

136 DNP-enhanced (19)F MAS NMR spectroscopy for structural characterization of HIV-1 CA assemblies, and

137 by a lack of dynamics measurements with and structural characterization of homogeneous isotypically

138 While structural characterization of homotypic chains has been

139 In summary, our structural characterization of human IP(3)R-3 provides c

140 isotope labeling required for a detailed NMR structural characterization of IGF-II analogs that revea

141 s approach for label-free identification and structural characterization of individual viruses that i

142 s received increased attention; however, the structural characterization of intact precursor proteins

143 Detailed structural characterization of intact rough-type lipopol

144 Previous structural characterization of integrase-viral DNA compl

145 of their large conformational heterogeneity, structural characterization of intrinsically disordered

146 a tool for quantitation and molecular-scale structural characterization of ionomers and proteins wit

147 ile X-ray crystallography routinely provides structural characterization of kinetically stable pre-ca

148 High-resolution structural characterization of lattices formed in the pr

149 Our structural characterization of LpSpl and its comparison

150 study, we present a novel method that allows structural characterization of mAbs based on MALDI in-so

151 analytical methods that afford comprehensive structural characterization of mAbs to ensure their stri

152 unique capabilities of X-ray scattering for structural characterization of materials in their native

153 Structural characterization of Mediator is challenging d

154 We then carried out an exhaustive structural characterization of metastable states on the

155 The structural characterization of modular proteins containi

156 increasingly common and useful technique for structural characterization of molecules in solution.

157 S) is an important property that aids in the structural characterization of molecules.

158 mass spectrometry in the identification and structural characterization of molecules.

159 In addition, we present the first structural characterization of MOLP and oxidative additi

160 Structural characterization of MOS was carried out using

161 Herein, we describe the first structural characterization of N-alkylated twisted amide

162 hich opens up exciting opportunities for the structural characterization of nanocrystals and their as

163 Structural characterization of new alpha/gamma-peptide f

164 ization compatibility, which will enable the structural characterization of new NEMO/inhibitor comple

165 s simulations represents a powerful tool for structural characterization of not only isolated membran

166 Here, we describe the development and structural characterization of novel Escherichia coli Cu

167 In this study, we describe the structural characterization of novel flagellar glycans f

168 In situ structural characterization of numerous synaptic protein

169 One of the major challenges in structural characterization of oligosaccharides is the p

170 Structural characterization of one of these V2 Abs revea

171 As), has emerged as a powerful technique for structural characterization of organic small molecules.

172 s of MsbA to flip LPS, and paves the way for structural characterization of other lipid flippases.

173 The only current structural characterization of PE-PPE-EspG heterotrimers

174 Energetic insights emerging from the structural characterization of peptide cross-beta assemb

175 ays a foundation for further biochemical and structural characterization of PhaC, which could assist

176 A structural characterization of polysaccharides from edib

177 We report here on the design and structural characterization of potent peptidic inhibitor

178 of the B cell repertoire, and the increasing structural characterization of protective antigens and e

179 ern day drug discovery and requires detailed structural characterization of protein-ligand interactio

180 Structural characterization of protein-protein interacti

181 ectroscopy is a nondestructive technique for structural characterization of proteins and polypeptides

182 Structural characterization of proteins in the gas phase

183 stal production is a major bottleneck in the structural characterization of proteins.

184 ful application of Raman spectroscopy is the structural characterization of proteins.

185 upled with computational methods enables the structural characterization of purified 3-ring and 4-rin

186 lar probe to advance further mechanistic and structural characterization of RABV G that may aid in th

187 ethod expands the application of sPRE beyond structural characterization of rigid proteins and comple

188 state transition remains debated despite the structural characterization of several archaeal M42 amin

189 oelicolor, leading to the identification and structural characterization of six polyketides (three kn

190 Structural characterization of small molecule binding si

191 for HRAM MS and EID to be used as a tool for structural characterization of small molecules with a wi

192 wing discrimination of cathinone isomers and structural characterization of small molecules, includin

193 We describe the isolation and detailed structural characterization of stable toxic oligomers of

194 knockouts provided negative controls for the structural characterization of stereid secondary cell wa

195 The structural characterization of sublayer surfaces of MIL-

196 We present here the first detailed structural characterization of such a target protection

197 The structural characterization of such diamonds remains a c

198 Structural characterization of sulfated glycosaminoglyca

199 We report the synthesis and structural characterization of the ABX(3) perovskite fra

200 Despite recent structural characterization of the AQP0-CaM complex, the

201 hensive review describes the biochemical and structural characterization of the ARD family, the propo

202 Furthermore, structural characterization of the assembly of these bet

203 We present the first structural characterization of the Axl kinase domain in

204 Detailed structural characterization of the catalyst binding site

205 Spectroscopic and structural characterization of the complex indicated red

206 linked to schizophrenia, a C4 inhibitor and structural characterization of the convertase formed by

207 lus licheniformis, along with solution-phase structural characterization of the Cu(I)-LPMO, showing t

208 Here, we performed a systematic structural characterization of the Cyt toxin interaction

209 the process of conducting these studies, rR structural characterization of the dioxygen adduct of LP

210 Structural characterization of the dynamic peptide/prote

211 s of these crystals by SFX should now enable structural characterization of the early events that dri

212 Here, we report the biochemical and structural characterization of the EctA enzyme from the

213 However, significant challenges exist for structural characterization of the enzymes responsible f

214 Therefore, structural characterization of the FERM-folded active ta

215 We disclose the synthesis and structural characterization of the first acid-free anion

216 re, we report synthesis, crystal growth, and structural characterization of the first polynuclear hyd

217 a rational design as well as functional and structural characterization of the first self-assembling

218 Structural characterization of the free and MDM2-bound C

219 red states of proteins, we provide a precise structural characterization of the free energy landscape

220 Full structural characterization of the full-length oligomeri

221 Breakthroughs in the structural characterization of the HIV-1 Env trimer have

222 inal helical zinc-binding domain and provide structural characterization of the linked JmjN-JmjC doma

223 the first, to our knowledge, high-resolution structural characterization of the major components of t

224 sing an integrative approach, we provide the structural characterization of the major components of t

225 The protocol will open the way to structural characterization of the many glycosylated and

226 11 of MgsG (i.e., DH11) in vivo, followed by structural characterization of the metabolites accumulat

227 We report the structural characterization of the mu-selective endogeno

228 Both biochemical and structural characterization of the mutants suggested tha

229 Here we describe the structural characterization of the N-linked glycan modif

230 Structural characterization of the O-linked glycans rele

231 The structural characterization of the pathway along with st

232 The structural characterization of the phage tail after ejec

233 nteractions, these limitations had precluded structural characterization of the PIC.

234 Two-dimensional NMR structural characterization of the polysaccharide, named

235 By completing our structural characterization of the previously unknown N-

236 Structural characterization of the product revealed it t

237 Solution and solid-state structural characterization of the protein in complex wi

238 Structural characterization of the RAM linker with sedim

239 present a detailed in vitro biochemical and structural characterization of the S100B-RSK1 interactio

240 Full spectroscopic and structural characterization of the siloxide products is

241 of state 1-stabilizing conditions may enable structural characterization of the state 1 conformation

242 Structural characterization of the Stx2a-ribosome comple

243 a crystalline matrix provides a platform for structural characterization of the transient species at

244 Herein, we report the isolation and structural characterization of the trinuclear electron-t

245 sent thorough kinetic analyses combined with structural characterization of the VCA0947 SpeG enzyme f

246 ng to the significant complexity of LOS, the structural characterization of these amphipathic lipids

247 g amyloid fibril formation, facilitating the structural characterization of these assembly intermedia

248 s work not only offers new opportunities for structural characterization of these chemically and indu

249 Structural characterization of these complexes, includin

250 ivo, and here, we report the biochemical and structural characterization of these enzymes.

251 Despite their potential, structural characterization of these glycan epitopes rem

252 However, due to their ephemeral nature, structural characterization of these species remains cha

253 In the absence of structural characterization of these species, methodolog

254 The covalent protein-ligand linkage enabled structural characterization of these trapped, off-pathwa

255 DNA packaging for the Dependoparvovirus The structural characterization of these viruses provides a

256 systematic mutagenesis and spectroscopic and structural characterization of this histidine and surrou

257 trimers in state 1, potentially facilitating structural characterization of this unknown conformation

258 ygenated diterpenoids, which in turn enabled structural characterization of three novel compounds pro

259 Here we report biochemical and structural characterization of TnmH from the tiancimycin

260 Here we present a functional and structural characterization of two closely related AA9-f

261 Here, we present a functional and structural characterization of two proteins of viral rho

262 The analysis also led to the structural characterization of two reactive precolibacti

263 monstrate the high-resolution separation and structural characterization of underivatized neutral and

264 In addition, we also report the structural characterization of vDHBPS in its apo form an

265 his work we performed a detailed kinetic and structural characterization of Vibrio cholerae WT ApbE a

266 Here we report structural characterization of wild-type and R882H-mutat

267 Herein, we report the in vivo, in vitro, and structural characterizations of a nonheme diiron monooxy

268 Structural characterizations of the cyclic 6- and 12-mem

269 eport systematic high-pressure transport and structural characterizations of the newly discovered sup

270 we review key findings in the functional and structural characterizations of these channels and highl

271 m-phage dynamics are genetic, molecular, and structural characterizations of these groups of phages.

272 Functional and structural characterizations of TRPV1 shed light on vani

273 patial resolution TOF-SIMS imaging and MS/MS structural characterization offers new opportunities for

274 and HREM investigations were carried out for structural characterization on the two alloy systems.

275 alginate oligosaccharide production and for structural characterization or modification of alginates

276 ng with the achieved separation and in-depth structural characterization, our approach can be used fo

277 However, its structural characterization remains undetermined.

278 genome analysis combined with isolation and structural characterization represents a phylogenetic ap

279 Structural characterization revealed symmetrically bridg

280 High resolution TEM/SAED structural characterization revealed that Al2O3 coatings

281 Initial structural characterization revealed that our most effec

282 Combined electrochemical and structural characterization reveals the electrode compos

283 Structural characterizations show that the transferred f

284 hermo-optical technique, thermal analysis by structural characterization (TASC), that can provide spa

285 Here, we present systematic structural characterizations that reveal the molecular b

286 gh these STFs have been extensively used for structural characterization, their functional evaluation

287 f truly monodisperse nanoparticles and their structural characterization to atomic precision are impo

288 X-ray scattering is a structural characterization tool that has impacted diver

289 Consequently, structural characterization typically requires molecular

290 Composition and structural characterization using field emission scannin

291 on processes that occur and was supported by structural characterization using small-angle neutron sc

292 Structural characterization via NMR spectroscopy reveale

293 Structural characterization was performed on an antibody

294 the IL-10.GAG complex could be obtained, its structural characterization was possible by NMR spectros

295 linical evaluation as well as functional and structural characterization, we established p.G411S as a

296 Through detailed electrochemical and structural characterization, we have shown that the enha

297 guingly, using biochemical, biophysical, and structural characterization, we reveal two distinct mech

298 and defects, which can only be understood by structural characterization with high spatial 3D resolut

299 Structural characterization with optical and electron mi

300 unds are presented, along with comprehensive structural characterizations (X-ray diffraction, electro