ライフサイエンスコーパス: structural fluctuation

1 to changes in both solvent accessibility and structural fluctuations.

2 -induced increase in the amplitudes of local structural fluctuations.

3 identical properties and exhibit independent structural fluctuations.

4 dielectric capacitors via manipulating local structural fluctuations.

5 ation selectivity, while revealing localized structural fluctuations.

6 structures involved or the magnitude of the structural fluctuations.

7 ive to the ever-present background of faster structural fluctuations.

8 y proteins, such as enzymes, is modulated by structural fluctuations.

9 ly metastable first-order LLT and pronounced structural fluctuations along its supercritical continua

10 We find larger-than-expected structural fluctuations and bond lengths for heavy Ln-OD

11 in the system, leading to the evident local structural fluctuations and concomitant polymorphic pola

12 re controlled by temperature dependent local structural fluctuations and crystal fluidity.

13 holipid bilayers under osmotic stress allows structural fluctuations and deformation of membranes to

14 Heating triggered structural fluctuations and dissociation events, generat

15 bond in the portal region, thereby arresting structural fluctuations and effectively locking the liga

16 roduced fresh insights into the interplay of structural fluctuations and electronic properties in a b

17 ocess model, consisting of EX2-limited local structural fluctuations and EX1-limited global unfolding

18 ntaining the G:A mismatch showed much larger structural fluctuations and failed to adopt a well-defin

19 vide insights into the nature of large-scale structural fluctuations and flexibility of the nucleosom

20 llective interactions manifest that minimize structural fluctuations and give rise to enhanced thermo

21 ile Red is shown to be a useful probe of the structural fluctuations and heterogeneity of these membr

22 paration of allosteric motion into intrinsic structural fluctuations and ligand-induced contributions

23 Structural fluctuations and molecular excitations of hyd

24 pted with a point mutation that limits local structural fluctuations and rescued with compensating mu

25 solvent model reproduced the average protein structural fluctuations and sample conformations similar

26 unfolding in equilibrium, graded increase in structural fluctuations and temperature-dependent swelli

27 esults were also used to analyze the peptide structural fluctuations and the free-energy surface of h

28 The spatial extent of structural fluctuations appears highly dependent on both

29 ed, but as a result of allosteric effect the structural fluctuations are altered significantly, which

30 supporting early claims that its equilibrium structural fluctuations are larger than those of the WT

31 at the reorientation of SeCN(-) and the RTIL structural fluctuations are substantially slower in the

32 Localized structural fluctuations are the primary physical origin

33 We found that dynamics (structural fluctuations) are essential in explaining oxi

34 whole cells at 0 degrees C but with sizable structural fluctuations associated with local mobility.

35 (CH(3)NH(3))PbI(3) the dynamics and ensuing structural fluctuations associated with the (CH(3)NH(3))

36 mic crystallization proceeds through dynamic structural fluctuations between disordered and crystalli

37 pores with dimethylformamide (DMF) slows the structural fluctuations by reducing the ability of the M

38 We propose that rapid local structural fluctuations cause the self-trapped excitons

39 ns, and propose an explanation based on rare structural fluctuations caused by intrinsic nanoscale in

40 f an isotropic external force, combined with structural fluctuations, causes structurally heterogeneo

41 in decreased folding free energy and larger structural fluctuations compared with those of wild-type

42 Structural fluctuations continuously expose internal DNA

43 estigation examines whether and how specific structural fluctuations contribute to desolvation of the

44 The simulations reveal significant structural fluctuations corresponding to lateral opening

45 of the initial diffusional encounter and of structural fluctuations determine the overall rate of th

46 pairs in DNA that become open as a result of structural fluctuations, DNA bending, or protein-DNA int

47 e analysis were used to infer that intrinsic structural fluctuations dominate LID motion, whereas lig

48 nformational restrictions and control of the structural fluctuation dynamics.

49 r every intermediate in the catalytic cycle; structural fluctuations efficiently channel the enzyme t

50 We suggest that these structural fluctuations expose a nucleation point for ps

51 tend to be disulfide-insecure, in that their structural fluctuations expose their disulfide bonds in

52 Many proteins rely on rare structural fluctuations for their function, whereby solv

53 to approximately 100 ps) protein equilibrium structural fluctuations have not been characterized expe

54 MOF in low concentration, revealed that the structural fluctuations have time constants of 7 and 670

55 transformations, we demonstrate that global structural fluctuations help promote substrate-dependent

56 w fragment) and LdG-DNA duplex elucidate the structural fluctuations imparted by the LdG lesion, as w

57 To study the role of structural fluctuation in fine-tuning DNA affinity, we p

58 idin is achieved mainly through constraining structural fluctuations in F-actin and suggests that fac

59 se A, and discuss its application to probing structural fluctuations in folded proteins.

60 -ray diffuse scattering to uncover universal structural fluctuations in La(2-x)Sr(x)CuO(4) and Tl(2)B

61 Here we show that local structural fluctuations in magnetite emerge below the Cu

62 Analysis of structural fluctuations in the bound and unbound states

63 me, and emphasizes the necessity for dynamic structural fluctuations in the catalytic mechanism of sm

64 en structure of SAHH lead to the presence of structural fluctuations in the direction of the open-to-

65 roach for imaging the changes of statistical structural fluctuations in the first stage of myelin deg

66 of its allosteric transition, accompanied by structural fluctuations in the heme pocket of the beta-c

67 These observations suggest that the slower structural fluctuations in the hydrophobic core, indicat

68 ion of the LR and the TSH ligand reduces the structural fluctuations in the LR.

69 rovide further characterization of the large structural fluctuations in the native states of proteins

70 cted accessibility to oxygen indicating that structural fluctuations in the protein provide intermole

71 The enhanced structural fluctuations in Ti-, Zr- and Cu-based BMG sys

72 g intensities are consistent with a model of structural fluctuations in which secondary structures un

73 to provide ultrafast snapshots of molecular structural fluctuations, in analogy with multidimensiona

74 in with those of its modified forms revealed structural fluctuations induced by post-translational mo

75 However, the nanoscale structural fluctuations intrinsic to these superlattices

76 Its origin lies in the strong structural fluctuations introduced by the spatially exte

77 We thus propose that matching of structural fluctuations is a component of how TCRs scan

78 lthough a native-like structure is retained, structural fluctuations lead to attenuation of selected

79 w that these modifications promote or dampen structural fluctuations, likely through competing effect

80 es formed by the C9-NRE DNA are stable, with structural fluctuations limited to the cytosine-containi

81 We show that the structural fluctuations manifest themselves in correlate

82 t the allosteric effector-induced quaternary structural fluctuation may contribute to the reduced lig

83 mparisons for COX-1 versus COX-2 active site structural fluctuations may also provide useful informat

84 Although structural fluctuations may be expected to have an impor

85 Thus, tailored orbital symmetry and structural fluctuations may be used to produce coherent

86 ng, multistep ordered assembly pathways, and structural fluctuations occurring within fully assembled

87 Structural fluctuations of a protein are essential for a

88 clear plasticity, correlated spatio-temporal structural fluctuations of chromatin in undifferentiated

89 On the other hand, structural fluctuations of DNA give rise to steric colli

90 modeling-with which we filmed the nanoscale structural fluctuations of individual, suspended, and un

91 provides detailed information regarding the structural fluctuations of lipid bilayers, including bot

92 f solids, we demonstrate a common scaling of structural fluctuations of lysozyme protein embedded in

93 e-shaping techniques can probe the ultrafast structural fluctuations of MOFs.

94 the 2D-IR results demonstrate that the fast structural fluctuations of Ngb are significantly slower

95 d for the conformational entropy provided by structural fluctuations of proteins exists, beyond which

96 The local structural fluctuations of SAHH are analyzed by performi

97 By systematically comparing the structural fluctuations of the capsid protein, a strong

98 ared to a 15 ns simulation of apo-mAChE, the structural fluctuations of the enzyme are substantially

99 mp-probe experiments were connected to local structural fluctuations of the free volume elements.

100 mputer simulations show that restricting the structural fluctuations of the h4 helix is key to rigidi

101 plete orientational randomization of CO2 and structural fluctuations of the IL (spectral diffusion) i

102 intramolecular disulfide bond places on the structural fluctuations of the protein neuroglobin (Ngb)

103 sity to applied field, laser wavelength, and structural fluctuations of the QD.

104 Structural fluctuations of these ionic clusters result i

105 re also used to assess the spatial extent of structural fluctuations of various hemoglobins in soluti

106 The effects of structural fluctuations on charge transfer in double-str

107 al conditions, proteins continuously undergo structural fluctuations on different timescales.

108 ne the amplitudes and time scales of protein structural fluctuations on fast time scales.

109 Some key regions of the protein feature structural fluctuations on nanosecond time scales, which

110 egments in oriented specimens, and measuring structural fluctuations on the microsecond time scale.

111 Relaxation measurements on NRho reveal structural fluctuations on the microseconds-milliseconds

112 the ribosome, the nascent peptide undergoes structural fluctuations on the us time scale.

113 d theoretical analyses support the idea that structural fluctuations originate from size-dependent th

114 phatidylcholine binding drives unanticipated structural fluctuations outside of the canonical activat

115 Proteins exhibit structural fluctuations over decades of time scales.

116 order was recently discovered and associated structural fluctuations persisting above T(V) are widely

117 ctron-proton transfer processes, where local structural fluctuations play a pivotal role.

118 d to be disulfide-secure, meaning that their structural fluctuations preferentially expose their thio

119 are governed by the magnitude of the random structural fluctuations present in water.

120 Structural fluctuations promoted by these defective moti

121 subunit in the tetramer, but the associated structural fluctuations propagate across the entire beta

122 We postulate that antennae design mitigates structural fluctuations, providing a mechanism for robus

123 These results indicate that structural fluctuations rather than the time-averaged st

124 at the selectivity filter, thus resulting in structural fluctuations, reduced K(+) affinity, and incr

125 periodically the molecule exhibits dramatic structural fluctuations represented by the opening and c

126 Analysis of such structural fluctuations reveals the local mechanical pro

127 Principal component analysis (PCA) of the structural fluctuations shows that the binding of enzalu

128 Detailed analysis of the structural fluctuations shows that the stability differe

129 hat deoxy-Hb A exhibits substantially larger structural fluctuations than HbCO A.

130 titute the thermodynamic epiphenomena of the structural fluctuation that accompanies ligand-receptor

131 Nucleation is generally viewed as a structural fluctuation that passes a critical size to ev

132 Translocation of proteins is correlated with structural fluctuations that access conformational state

133 eric sites play a pivotal role in activating structural fluctuations that allosterically modulate fun

134 the submillisecond timescale into localized structural fluctuations that are coupled to the active s

135 binding sites and ligand-induced changes to structural fluctuations that are distant from the bindin

136 We conclude that there can be major structural fluctuations that are only weakly coupled to

137 at the characteristics of the native protein structural fluctuations that cause proton nuclear spin-l

138 ion, are admissible and result in only minor structural fluctuations that do not affect overall compl

139 is accompanied by a substantial reduction of structural fluctuations that dominate in the apo structu

140 tes and undergo TADF versus larger amplitude structural fluctuations that lead to non-radiative decay

141 ron spin-echo spectroscopy was used to study structural fluctuations that occur in hemoglobin (Hb) an

142 Identification and characterization of structural fluctuations that occur under native conditio

143 nteractions between Y(32) and E(13), through structural fluctuations that reorient surrounding side c

144 d binding can modulate the extent of protein structural fluctuations that transiently disrupt hydroge

145 nd intrinsically on both molecular shape and structural fluctuations, thereby providing the enticing

146 oms, we proposed a method of enhancing local structural fluctuation to refine the polar configuration

147 es within this key region, we decrease local structural fluctuations to slow ataxin-3 aggregation.

148 ed by large energetic barriers that minimize structural fluctuations under physiological temperatures

149 has been typically assumed, but experiences structural fluctuations upon binding ligands.

150 ime of 2.1 mus), the relaxation time of tRNA structural fluctuations was determined to be approximate

151 By taking into account structural fluctuations, we can determine structures wit

152 g into consideration geometrical factors and structural fluctuations, we show that ions tend to be bo

153 pair exhibits considerably larger and faster structural fluctuations when polarization is included, d

154 bility and insensitive to changes in protein structural fluctuations, whereas HDX is sensitive to cha

155 celle, the cytoplasmic helices undergo large structural fluctuations, whereas the transmembrane pore

156 ion in the portal region arrests large-scale structural fluctuations, which are required for retinoic

157 ar exist where function can be correlated to structural fluctuations with known magnitude and timesca

158 RNA and show that it requires specific local structural fluctuations within a key hairpin to engender

159 We report the direct observation of structural fluctuations within a single nanocrystal usin

160 tacts both actin and polyproline, as well as structural fluctuations within the actin- and polyprolin