ライフサイエンスコーパス: subaortic

1 ranscriptional circuitry operating in future subaortic and subpulmonary OFT myocardium.

2 r mitral leaflet, forming the characteristic subaortic bump.

3 n, the left atrium is continuous through the subaortic curtain with the musculature of the anterior m

4 valve area with changes in flow rate and the subaortic flow profile have been performed.

5 ation of symptoms and about 50% reduction in subaortic gradient over >/=3 years.

6 Furthermore, abolition of subaortic gradients by surgical myectomy (or percutaneou

7 Assessment of subaortic gradients with exercise should be a routine co

8 re (n=17), aortic annulus enlargement (n=2), subaortic membrane resection (n=9), arch augmentation (n

9 major VSD in 2, pulmonary stenosis in 2 and subaortic membrane, atrial septal defect and mitral regu

10 normally acts to repress BMP activity in the subaortic mesenchyme through transcriptional inhibition

11 he via its regulation of BMP activity in the subaortic mesenchyme.

12 the septum, but also basal inferior wall and subaortic mitral continuity.

13 Concomitantly, the superior OFT and subaortic myocardium are expanded.

14 way negatively regulates Ppargamma in future subaortic myocardium in the superior OFT wall.

15 In addition, the alphaMHC-BMP10 mice develop subaortic narrowing and concentric myocardial thickening

16 w tract diameter of >2.0 was associated with subaortic obstruction (P=0.001).

17 of leaflet length and mobility that affects subaortic obstruction also influences mitral regurgitati

18 lic anterior motion (SAM), which causes both subaortic obstruction and mitral regurgitation.

19 conal septum that divides subpulmonary from subaortic outlets.

20 patient cohorts that unequivocally supports subaortic pressure gradients (and obstruction) both as t

21 ) after mitral valve replacement, and in the subaortic region in 3 of 3 (100%) after aortic valve rep

22 ure beyond the neonatal period and those had subaortic resection.

23 and decreased atherosclerotic lesions in the subaortic sinus (158.1+/-44.4 and 330.1+/-109.5x10(3)mum

24 ation after successful resection of discrete subaortic stenosis (DSS).

25 heart disease in the complex group included subaortic stenosis (n=20), arch obstruction (n=7), mitra

26 ties that have been associated with discrete subaortic stenosis (SAS) in children.

27 The diagnosis of subaortic stenosis (SAS) is often made before significan

28 ups were evaluated-33 patients with isolated subaortic stenosis and 12 patients with perimembranous v

29 ss the postoperative progression of discrete subaortic stenosis and aortic regurgitation, as well as

30 ata suggest that surgical resection of fixed subaortic stenosis before the development of a significa

31 patients with ventricular septal defect and subaortic stenosis compared with control subjects (p < 0

32 Subaortic stenosis constitutes up to 20% of left ventric

33 ft ventricular outflow tract associated with subaortic stenosis in children.

34 Considerable evidence suggests that subaortic stenosis is an acquired and progressive lesion

35 This study demonstrates that subaortic stenosis is associated with a steepened aortos

36 however, reoperation for recurrent discrete subaortic stenosis is not uncommon.

37 Discrete subaortic stenosis is notable for its unpredictable hemo

38 e need for intervention for mitral or aortic/subaortic stenosis is uncommon.

39 ersistent CHB: (1) aortic valve replacement, subaortic stenosis repair, or Konno procedure; (2) ventr

40 tomy, mitral valve replacement, aortoplasty, subaortic stenosis resection, ventricular septal defect

41 uloplasty (n=56), coarctation repair (n=21), subaortic stenosis resection/Konno procedure (n=10), ven

42 angle was steeper in patients with isolated subaortic stenosis than in control subjects (p < 0.001).

43 ho previously underwent surgery for discrete subaortic stenosis were included in this retrospective m

44 ifically relating steep aortoseptal angle to subaortic stenosis, confirm the results of other investi

45 perimembranous ventricular septal defect and subaortic stenosis-and were compared with a size- and le

46 gurgitation, severe aortic regurgitation, or subaortic stenosis.

47 may be a risk factor for the development of subaortic stenosis.

48 early resection can improve outcome in fixed subaortic stenosis.

49 age etiologic process for the development of subaortic stenosis.

50 utflow tract present in patients who develop subaortic stenosis.

51 ival is excellent after surgery for discrete subaortic stenosis; however, reoperation for recurrent d

52 function as a subpulmonary ventricle or as a subaortic (systemic) ventricle in transposition complexe

53 A subaortic ventricular outflow tract gradient >30 mm Hg i

54 fter birth, likely resulting from a profound subaortic ventricular septal defect and associated malal