ライフサイエンスコーパス: subcapsular

1 lassified as nuclear, cortical, or posterior subcapsular.

2 eneously, 109 had a smooth surface, 101 were subcapsular, 89 had ill-defined margins, and 62 had a ce

3 As opposed to the clear DNA-free subcapsular and cortical areas of young adult mouse lens

4 In aged mice, most subcapsular and cortical cataracts colocalize with accum

5 nset of heart failure and the development of subcapsular and cortical cataracts is observed in Mbnl3(

6 vital dyes, to determine whether age-related subcapsular and cortical cataracts were linked to the fa

7 oped that initially appeared to be posterior subcapsular and gradually matured to involve the entire

8 lipopolysaccharide, were very visible in the subcapsular and medullary sinuses but were largely exclu

9 a recta in the renal medulla, the lymph node subcapsular and medullary sinuses, and some capillaries

10 ly associated with the severity of posterior subcapsular and nuclear cataracts, which was the only fe

11 immature nuclear sclerotic, mature posterior subcapsular, and mature nuclear.

12 s; nanoparticles were found in the cortical, subcapsular, and medullary sinuses.

13 NK cells located in the subcapsular area exhibited reduced motility and were fou

14 sults in the accumulation of NK cells in the subcapsular area of the draining lymph node and their ac

15 sk if they were located in the subphrenic or subcapsular areas of the liver or less than 1 cm from th

16 gions in the medullary, interfollicular, and subcapsular areas where viral infection was initially co

17 itating reticulum cells of T zones, cells in subcapsular areas, and cells of the reticular network we

18 l, posterior subcapsular (PSC), and anterior subcapsular (ASC), all of which succeeded a characterist

19 lpha-1,3-galactosyltransferase gene and with subcapsular autologous thymic tissue.

20 FUS eyes included vitritis (100%), posterior subcapsular cataract (96%), stellate keratic precipitate

21 rotic diseases in the lens, such as anterior subcapsular cataract (ASC) formation.

22 C-501, including retinal detachment (n = 4), subcapsular cataract (n = 1), and glaucoma (n = 1).

23 higher odds of PACD, whereas late posterior subcapsular cataract (PSC) (OR, 0.60; 95% CI, 0.48-0.76)

24 ciated with a higher prevalence of posterior subcapsular cataract (PSC) (OR, 1.29; 95% CI, 1.07-1.55)

25 te a possible relationship between posterior subcapsular cataract (PSC) formation and expression of t

26 cities formed during recovery from posterior subcapsular cataract (PSC) in Royal College of Surgeons

27 presence of cortical, nuclear, or posterior subcapsular cataract (PSC) opacification in at least one

28 s opacity (CLO; scale 0%-100%) and posterior subcapsular cataract (PSC; scale 0%-100%) from retroillu

29 were correlated to the severity of posterior subcapsular cataract (r = 0.4, P = .0006).

30 ty, except for variable mild local posterior subcapsular cataract and local retinal toxicity with hig

31 lation was evident between risk of posterior subcapsular cataract and size at birth.

32 95% CI, 1.27-2.87; P = 0.002); and posterior subcapsular cataract increase of 5% or more versus less

33 aract, and any role in cortical or posterior subcapsular cataract is scarcely measurable.

34 ers (OR, 1.28; 95% CI, 0.79-2.08); posterior subcapsular cataract occurred in 3.0% of statin users an

35 I 0.96-1.63) cataracts, but not to posterior subcapsular cataract or cataract surgery.

36 ual acuity declined to 6/60 due to posterior subcapsular cataract progression.

37 act, 1.95 (95% CI: 0.48, 7.95) for posterior subcapsular cataract, 1.82 (95% CI: 0.91, 3.66) for soft

38 95% CI, 0.78-1.65; P = 0.519); and posterior subcapsular cataract, 3.05 (95% CI, 1.79-5.19; P < 0.001

39 arRP, early macular degeneration, posterior subcapsular cataract, and myopia.

40 maculopathy, open-angle glaucoma, posterior subcapsular cataract, and retinal detachment, respective

41 The associations of lens features (posterior subcapsular cataract, nuclear color, nuclear white scatt

42 .82, 95% CI: 0.68, 0.97; primarily posterior subcapsular cataract, RR = 0.90, 95% CI: 0.71, 1.13).

43 ear white scatter, cortical spokes, anterior subcapsular cataract, vacuoles, waterclefts, coronary fl

44 iations were found between PXS and posterior subcapsular cataract.

45 ion were associated with extent of posterior subcapsular cataracts (PSC) that were diagnosed at a med

46 n 50% of NF2 patients also develop posterior subcapsular cataracts (PSCs).

47 es regarding the pathophysiology of anterior subcapsular cataracts secondary to posterior chamber pIO

48 ptor 1) began to develop bilateral posterior subcapsular cataracts that progressed to lens rupture an

49 Posterior subcapsular cataracts were documented in 36.4% of eyes.

50 Posterior subcapsular cataracts were present in 97.5% of patients.

51 yctalopia, vision reduction, early posterior subcapsular cataracts, and varying degrees of myopia.

52 ar incident nuclear, cortical, and posterior subcapsular cataracts, but was related to incident catar

53 .23-2.27), but not to cortical and posterior subcapsular cataracts.

54 t laxity, skin hyperelasticity and bilateral subcapsular cataracts.

55 ce from the four families exhibited anterior subcapsular cataracts.

56 raphs were graded for cortical and posterior subcapsular cataracts.

57 resembled the plaques seen in human anterior subcapsular cataracts.

58 al dominant "progressive childhood posterior subcapsular" cataracts segregating in a white family to

59 We observed that mice with adrenal subcapsular cell hyperplasia (SCH), a common histologica

60 is triggered by the interaction of bacterial subcapsular components and bone marrow-derived DC (likel

61 fr2(UB-/-) kidneys have abnormally thickened subcapsular cortical stromal mesenchyme.

62 th hydrocortisone induced both medullary and subcapsular cortical TE cells to express CK6, a differen

63 gitidis and that in each case, the bacterial subcapsular domain markedly influences the Ig response t

64 osition and/or architecture of the bacterial subcapsular domain.

65 mains unresolved whether different bacterial subcapsular domains can exert differential effects on PS

66 sues, high endothelial venules and basal and subcapsular epithelia are CD164 class II-positive, while

67 le negative thymoctyes and laminin 5 made by subcapsular epithelial cells is required for the surviva

68 to the cell surface of thymic medullary and subcapsular epithelium.

69 differentiating fibers of the bow region and subcapsular fibers of the central zone, whereas the lens

70 oneal implants, intratumoral hemorrhage, and subcapsular fluid, showed a significant association with

71 When grown as a subcapsular graft, the Gli2(-/-) UGS exhibited prostatic

72 icities of these two important streptococcal subcapsular group polysaccharides to fully understand th

73 CT showed a voluminous subcapsular hematoma compressing the hepatic parenchyma,

74 s, ureteropelvic junction obstruction, renal subcapsular hematoma, cholelithiasis, medullary calcinos

75 acute liver failure occurs in patients with subcapsular hematoma.

76 including abruptio placentae, renal failure, subcapsular hematomas, and hepatic rupture.

77 Gross liver lesions, characterized by subcapsular hemorrhages or enlargement of the right inte

78 l vascular abnormalities, including aberrant subcapsular hepatic veins, enlarged glomeruli, intestina

79 NSG mice that had received renal subcapsular human islet allografts and were transfused w

80 murine model of chronic kidney disease, with subcapsular hydrogel injections acting as a delivery dep

81 density (foci per mm(2) cortex), percentage subcapsular IF/TA, striped IF/TA, percentage inflammatio

82 aft model of kidney cancer, characterized by subcapsular implantation of Caki-1 clear cell human kidn

83 n and outside IF/TA regions), and percentage subcapsular inflammation.

84 The renal subcapsular infusion of NPFF in C57BL/6 mice decreased r

85 Moreover, renal restricted subcapsular infusion of Snx5-specific siRNA (vs. mock si

86 ix pancreatic cancer cell lines and a spleen subcapsular inoculation nude mouse model were also used.

87 ion although they survived longer than renal subcapsular islet allografts.

88 The renal subcapsular islet graft was easily detectable on T2*-wei

89 ll to glucose challenge, comparable to renal subcapsular islet grafts, despite a marginal islet dose,

90 4 to prevent recurrence of diabetes in renal subcapsular islet isografts in DR-BB (RT1uu) rats with e

91 awbacks of the conventional method of kidney subcapsular islet transplantation.

92 normoglycemia faster than animals with renal subcapsular islet transplants.

93 tolerance of intratesticular, but not renal subcapsular, islet allografts.

94 onsive (>120 days) Lewis recipients of renal subcapsular islets underwent nephrectomy of the islet be

95 he lens; however, expression was confined to subcapsular LECs located along the anterior hemispheric

96 ed reading center for cortical and posterior subcapsular lens opacities and for AMD severity.

97 age-related nuclear, cortical, and posterior subcapsular lens opacities.

98 ted with an increased risk of mild posterior subcapsular lens opacity development.

99 ly in patients treated with chemotherapy, in subcapsular lesions, and in peribiliary metastases.

100 receptor CCR7 for their transition from the subcapsular lymph node sinus into the parenchyma, a migr

101 Depletion of subcapsular macrophages (SCMsmall ef, Cyrillic) or abrog

102 ing vaccination, where they were taken up by subcapsular macrophages and then resident dendritic cell

103 r the inguinal lymph node medullary, but not subcapsular macrophages, captured the protein, while scr

104 affected by the loss of F4/80(+) or CD169(+) subcapsular macrophages.

105 d.HGF-transduced NHP islets in vivo, a renal subcapsular marginal mass islet transplant model was dev

106 CD169(+) SIGNR1(+) subcapsular medullary macrophages are the primary cells

107 characterizing glomeruli in the superficial (subcapsular), middle, and deep (juxtamedullary) regions.

108 (2) Subcapsular necrotic areas in the liver suggestive of pr

109 ocal inflammation, and large grossly visible subcapsular necrotic foci.

110 innate and adaptive memory responses in the subcapsular niche can provide new opportunities to bolst

111 r pre-positioned or rapidly recruited to the subcapsular niche following infection and inflammation.

112 anticipated from earlier studies, posterior subcapsular, nuclear, and cortical cataracts were associ

113 d to UVB exhibited accelerated anterior lens subcapsular opacification, which was more pronounced in

114 ngle-strand breaks, as well as lens anterior subcapsular opacification.

115 aract (RR = 1.39), and preexisting posterior subcapsular opacities (RR = 6.67).

116 d cortical opacities as grade > or = 0.5 and subcapsular opacities as grade > or =0.3 of the Lens Opa

117 Cortical and posterior subcapsular opacities increased with age, but scores for

118 tations, 2 eyes had progression of posterior subcapsular opacities, although neither required surgery

119 graded for nuclear, cortical, and posterior subcapsular opacities, and the amount of liquid vitreous

120 iring nearwork, nuclear opacities, posterior subcapsular opacities, glaucoma, and ocular hypertension

121 ous opacity (both 12/50 eyes, 24%); type II: subcapsular opacity (214/399 eyes, 53.6%) and type III:

122 tical opacity as grade >/=1.0, and posterior subcapsular opacity as grade >/=0.5 according to the Len

123 OL showed either stage 5 (complete posterior subcapsular opacity) or stage 6 (mature) cataracts, wher

124 eye developed visually significant anterior subcapsular opacity, whereas another eye experienced pIO

125 ryl CoA reductase inhibitor, developed frank subcapsular opacity.

126 (OR, 1.57; 95% CI, 1.13-2.20) and posterior subcapsular (OR, 1.73; 95% CI, 1.10-2.72) cataract, but

127 stant cell renewal, involving recruitment of subcapsular progenitors to ZG fate and subsequent lineag

128 ivated to differentiate into plasma cells in subcapsular proliferative foci (SPF).

129 presence of cortical, nuclear, or posterior subcapsular (PSC) cataract at any visit, following the W

130 graded for nuclear, cortical, and posterior subcapsular (PSC) cataract, following the Wisconsin Cata

131 presence of nuclear, cortical, or posterior subcapsular (PSC) cataract, from standardized grading of

132 , including nuclear, cortical, and posterior subcapsular (PSC) cataract.

133 on Zone for nuclear, cortical, and posterior subcapsular (PSC) cataracts in vivo and photographically

134 cipants had nuclear, cortical, and posterior subcapsular (PSC) cataracts, respectively.

135 the odds of developing cortical or posterior subcapsular (PSC) cataracts.

136 entage involvement of cortical and posterior subcapsular (PSC) lens opacities within the central 5 mm

137 viduals with nuclear, cortical, or posterior subcapsular (PSC) opacities and individuals with no cata

138 e of diabetes, including cortical, posterior subcapsular (PSC), and anterior subcapsular (ASC), all o

139 ens for presence of nuclear (NSC), posterior subcapsular (PSC), and cortical cataract (CC), using the

140 tes assemble in clusters in the cords of the subcapsular red pulp and are distinct from macrophages a

141 lomeruli identified located in the immediate subcapsular region (P<0.001).

142 nsplanted, but most biopsies sample only the subcapsular region and may not accurately represent the

143 revealed laminin 5 expression mostly in the subcapsular region of the adult thymus.

144 Gp96 accesses the subcapsular region of the draining lymph node, and it is

145 ghout the cortex rather than confined to the subcapsular region of the thymus.

146 butes to pre-T cell development, as does the subcapsular region of the thymus.

147 onized by newly produced antibodies from the subcapsular region to the germinal center, and affinity

148 Naive T lymphocyte locomotion in the subcapsular region was 38% slower and had higher turning

149 a predominance of sclerosis in the kidney's subcapsular region, the area predominantly sampled by th

150 ry junction in lymphoid follicles and in the subcapsular region.

151 MBs were larger and more numerous in the subcapsular region.

152 /delta TCR expression especially high in the subcapsular region.

153 elop cataracts in the anterior and posterior subcapsular regions as well as punctate opacities in the

154 n DCs from the early stage in the lymph node subcapsular regions, and COX-2 inhibition markedly suppr

155 lant survival and blood glucose control in a subcapsular renal graft model in immuno-incompetent diab

156 The tissue recombinants were grown as subcapsular renal grafts and treated from the time of gr

157 tain innate-like lymphocytes that survey the subcapsular sinus (SCS) and associated macrophages for p

158 CD169+MHCII+ macrophages on the floor of the subcapsular sinus (SCS) and in the medulla of lymph node

159 The layer of macrophages at the subcapsular sinus (SCS) captures pathogens entering the

160 inate via lymphatics and preferentially bind subcapsular sinus (SCS) CD169(+) macrophages in tumor-dr

161 many B(EM) cells migrate into the lymph node subcapsular sinus (SCS) guided by sphingosine-1-phosphat

162 The floor LEC of the subcapsular sinus (SCS) in murine lymph nodes (LN) displ

163 ) alpha1beta2, which maintained a protective subcapsular sinus (SCS) macrophage phenotype within viru

164 were found associated with CD169(+)-positive subcapsular sinus (SCS) macrophages and collagen fibers.

165 Subcapsular sinus (SCS) macrophages are strategically po

166 Subcapsular sinus (SCS) macrophages capture antigens fro

167 cellular vesicles (EVs) that are captured by subcapsular sinus (SCS) macrophages in lymph nodes or an

168 y than naive T cells, relocalized toward the subcapsular sinus (SCS) near invaded macrophages, and en

169 LECs lining the subcapsular sinus (SCS) of LNs abundantly expressed neut

170 b(+)CD169(+) macrophages, which populate the subcapsular sinus (SCS) of LNs, are critical for the cle

171 by the mechanical 3D-sieve barrier of the LN subcapsular sinus (SCS).

172 mune cells to lymph nodes (LNs) and form the subcapsular sinus and cortical and medullary lymphatic s

173 s exploit CD169/Siglec-1-mediated capture by subcapsular sinus and marginal zone metallophilic macrop

174 in-water emulsion adjuvant MF59 localizes in subcapsular sinus and medullary macrophage compartments

175 Our findings identify macrophages lining the subcapsular sinus as an important site of B cell encount

176 , small numbers of beads were present in the subcapsular sinus as early as 6 h after inhalation.

177 CD1d-dependent manner in close proximity to subcapsular sinus CD169(+) macrophages.

178 Depletion of subcapsular sinus CD169-positive macrophages by clodrona

179 ng by lymphatic endothelial cells lining the subcapsular sinus ceiling stabilizes interfollicular CCL

180 borne antigens and chemoattractants from the subcapsular sinus directly to the B cell follicles.

181 ure that macrophages of the mouse lymph node subcapsular sinus facilitate B cell activation in vivo b

182 broblastic reticular cells that connects the subcapsular sinus floor and the HEVs by intertwining wit

183 In contrast, subcapsular sinus macrophages (SSMs) exposed to lymph-bo

184 In lymph nodes, subcapsular sinus macrophages (SSMs) form an immunologic

185 t contain the unprocessed Ag are captured by subcapsular sinus macrophages and are transferred onto f

186 resulting from S. flexneri interactions with subcapsular sinus macrophages and dendritic cells, and r

187 By contrast, large antigens were bound by subcapsular sinus macrophages and subsequently transferr

188 culate antigens relies on antigen capture by subcapsular sinus macrophages of the lymph node.

189 cate that NK-cell recruitment is mediated by subcapsular sinus macrophages, IFN-gamma, and CXCR3 duri

190 acquisition did not require dendritic cells, subcapsular sinus macrophages, or B cell movement to the

191 rticulate antigens and large IC are bound by subcapsular sinus macrophages.

192 nate-loaded liposomes, indicating a role for subcapsular sinus macrophages.

193 cles must be translocated into follicles via subcapsular sinus macrophages.

194 s (Mo) and B cell areas in the spleen and to subcapsular sinus Mo in lymph nodes of naive mice (CR-Fc

195 ymph node, exosomes were not retained in the subcapsular sinus of CD169(-/-) mice but penetrated deep

196 cells were identified in the paracortex and subcapsular sinus of the draining internal iliac lymph n

197 rough the lymphatic endothelial cells in the subcapsular sinus of the LN.

198 ith the removal of macrophages that line the subcapsular sinus of the lymph node.

199 n the marginal zone of the spleen and in the subcapsular sinus of the lymph node.

200 in the DLN, most of the LPS was found in the subcapsular sinus or medulla, near or within lymphatic e

201 Transcytosis through the floor of the subcapsular sinus thus represents what we believe to be

202 antigens diffuse directly from lymph in the subcapsular sinus to be acquired by antigen-specific B c

203 rt of small antigens and chemokines from the subcapsular sinus to follicular B cells.

204 ymph-borne soluble molecules travel from the subcapsular sinus to the HEVs is unclear.

205 luding chemokines, traveled rapidly from the subcapsular sinus to the HEVs using the reticular networ

206 njection, first in the region closest to the subcapsular sinus where lymph enters the lymph node.

207 endothelial cells lining the ceiling of the subcapsular sinus, but not those lining the floor, expre

208 d that antigens were rapidly degraded in the subcapsular sinus, paracortex, and interfollicular regio

209 ages that gave rise to FRCs underpinning the subcapsular sinus, T and B cell zones, and the medulla.

210 luorophore-labeled molecules highlighted the subcapsular sinus, the reticular fibers, and the ablumin

211 Liposomes were predominantly taken up by subcapsular sinus-lining macrophages, monocytes, and DCs

212 and infected cells residing just beneath the subcapsular sinus.

213 h the lymph to macrophages in the lymph node subcapsular sinus.

214 ion into the LN parenchyma from lymph in the subcapsular sinus.

215 tion of lymphoid stromal cells lining the LN subcapsular sinus.

216 vessels at the junction with the lymph node subcapsular sinus.

217 sinus macrophages, or B cell movement to the subcapsular sinus.

218 spite the microspheres being confined to the subcapsular sinus.

219 tor 1 (S1P1)-expressing CD68+ macrophages in subcapsular sinuses of FTY-P-treated MLNs.

220 ts of the niche that forms and maintains the subcapsular sinusoidal macrophage network in homeostasis

221 cessed islets were transplanted at the renal subcapsular site in rats.

222 In addition, the spatially limited renal subcapsular site restricts the mass of islet tissue that

223 r allografts were transplanted to the kidney subcapsular site.

224 st, porcine islets transplanted to the liver subcapsular space do not survive, although autologous is

225 2500, were transplanted into the left renal subcapsular space of a syngeneic adult mouse made diabet

226 -2d) islets were transplanted into the renal subcapsular space of diabetic c-Rel-/- C57BL/6 (H-2b) mi

227 ncreatic islets of Langerhans into the renal subcapsular space of immunodeficient BALB/c.rag2(-/-).cg

228 regeneration of prostatic structures in the subcapsular space of the kidney was observed within 4-8

229 ically, its expression was restricted to the subcapsular space of the LN during early inflammation, w

230 mokidney by thymic autografting to the renal subcapsular space results in normal thymic growth and fu

231 Control dogs received liver subcapsular space transplants of porcine islets and auto

232 n as few as 10 islets implanted in the renal subcapsular space, intrahepatic, intraabdominal, and sub

233 cells flowed from medullary sinuses into the subcapsular space.

234 re recovered and transplanted into the renal subcapsular space.

235 sorganized TEBs characterized by exaggerated subcapsular spaces, breaks in basal lamina, dissociated

236 These results suggest the presence of common subcapsular surface antigens, such as outer membrane pro

237 m-immunosuppressed TMX recipients with renal subcapsular syngeneic thymic grafts.

238 ls, BTM did not impair syngeneic islet renal-subcapsular transplant viability or function, and it fac

239 suing in vivo mature islets following kidney subcapsular transplantation in rats.

240 cified schedule starting 2 days before renal subcapsular transplantation of an islet isograft.

241 em cell-derived kidney organoids after renal subcapsular transplantation.

242 Twelve (75%) of 16 hemangiomas were subcapsular, two (12%) of 16 demonstrated exophytic grow

243 The nuclear, cortical, and posterior subcapsular types of cataracts did not show different re

244 fat planes obscured, retroperitoneal fluid (subcapsular vs extracapsular), ascites beyond the cul-de

245 tes downregulate CCR9 and migrate toward the subcapsular zone where they recombine their TCR beta-cha

246 across the cortex before accumulation in the subcapsular zone.