ライフサイエンスコーパス: subcellular distribution

1 2 treatment while maintaining its unexpected subcellular distribution.

2 homologue Kes1/Osh4 and regulate ergosterol subcellular distribution.

3 cluster size as a primary determinant of its subcellular distribution.

4 in interaction with VAMPs and affected their subcellular distribution.

5 odification that could possibly regulate its subcellular distribution.

6 Villin and Profilin, do not exhibit the same subcellular distribution.

7 vities, likely through mechanisms related to subcellular distribution.

8 C progression regulation was dictated by its subcellular distribution.

9 forms that differ mainly in their tissue and subcellular distribution.

10 inase A anchoring proteins, which alters its subcellular distribution.

11 These functions are controlled partly by its subcellular distribution.

12 ith age and SSc, and they exhibit an altered subcellular distribution.

13 pe littermates but still maintained a normal subcellular distribution.

14 ct on pendrin total and apical abundance and subcellular distribution.

15 and overlapping controls over expression and subcellular distribution.

16 molecular determinants of TRPV4 activity and subcellular distribution.

17 or the 5-HT(2A)R-dependent effects on mGluR2 subcellular distribution.

18 lized proteins exhibited prominent cytosolic subcellular distribution.

19 h a loss of restriction and an alteration of subcellular distribution.

20 fluorescent reporter of CaMKII activity and subcellular distribution.

21 2+) in cells, very little is known about its subcellular distribution.

22 nhibited HDAC3 activity but also altered its subcellular distribution.

23 ble, present lipid Ags, and have near normal subcellular distribution.

24 uenced incorporation into COPII vesicles and subcellular distribution.

25 in the regulation of CAST variants and CAST subcellular distribution.

26 demonstrates that most RNAs exhibit specific subcellular distribution.

27 nctions of GRP78 may result from its diverse subcellular distribution.

28 interneurons have distinct subglomerular and subcellular distributions.

29 Ca(2+) sensors with different affinities and subcellular distributions.

30 mechanotransduction channels with different subcellular distributions.

31 m to regulate their catalytic activities and subcellular distributions.

32 tau protein in glaucoma, including abnormal subcellular distribution, an altered phosphorylation pro

33 nitiated Akt-GSK3beta signaling mediates the subcellular distribution and activation of GLI1 resultin

34 patients truncates the protein, impairs its subcellular distribution and adversely affects its funct

35 periments revealed that trehalose alters the subcellular distribution and decreases the degradation o

36 the importance of tRNA for translation, its subcellular distribution and diffusion properties in liv

37 igated the mechanisms of p53-dependent BRCA1 subcellular distribution and DNA damage-induced nuclear

38 two conflicting hypotheses by evaluating the subcellular distribution and dynamics of Gal3 and Gal80

39 teins with an Ig-like domain, share the same subcellular distribution and ectodomain shedding propert

40 nd computational modeling to investigate the subcellular distribution and effects of GABA(B)Rs and th

41 aling, in turn, was found to influence Spry2 subcellular distribution and ERK, a Spry2 regulator.

42 ogical and optical approaches to examine the subcellular distribution and function of hyperpolarizati

43 Here we characterize the subcellular distribution and function of PS in the rod-s

44 ls and suggest mechanisms to account for the subcellular distribution and function of this phospholip

45 e report the first characterization of their subcellular distribution and identify a specific associa

46 me), a protein complex for which the precise subcellular distribution and mechanisms of action are un

47 Both approaches revealed similar subcellular distribution and membrane binding for both t

48 unknowns, including in vivo enzymatic rates, subcellular distribution and pathway interactions.

49 e are signal transduction centers, yet their subcellular distribution and preservation in cardiac myo

50 Here we systematically investigated the subcellular distribution and processing of major NRG iso

51 Subcellular distribution and protein expression levels i

52 TS-associated missense mutations alter their subcellular distribution and protein interactions, compr

53 2 genotype with NRG1-IVNV expression and the subcellular distribution and proteolytic processing of N

54 these findings provide new insights into the subcellular distribution and roles of specific PATs and

55 le of caveolin-1 (Cav-1) in modulating P2Y2R subcellular distribution and signaling in human 1321N1 a

56 ysically binds Vangl2 and regulates both the subcellular distribution and total protein level of Vang

57 Subcellular distribution and trafficking of labile Zn(2+

58 al questions about oxysterols, such as their subcellular distribution and trafficking pathways, remai

59 nkG expression caused significant changes in subcellular distribution and/or abundance of PKP2 and Co

60 ajor factors that determine cellular uptake, subcellular distribution, and as a consequence, the phot

61 potency, this compound has the permeability, subcellular distribution, and cell metabolism characteri

62 vels of expression (which vary by >30-fold), subcellular distribution, and coimmunoprecipitation anal

63 induced alterations in transporter activity, subcellular distribution, and dopamine efflux, but the r

64 er, the mechanisms regulating Alix turnover, subcellular distribution, and function in muscle cells a

65 arious molecular weight forms of K15P, their subcellular distribution, and how these may differ in la

66 n their enzymatic deubiquitination activity, subcellular distribution, and interaction with other pro

67 the dDis3 N-terminus also contributes to its subcellular distribution, and is necessary and sufficien

68 e activity of JMY in vitro and in cells, its subcellular distribution, and its function in fibroblast

69 photosensitizer (PS) affect cellular uptake, subcellular distribution, and photodynamic efficacy.

70 n membrane topology, protein processing, and subcellular distribution, and suggest that single- and d

71 -3 cDNA, and effects on beta-catenin levels, subcellular distribution, and Wnt signaling were determi

72 ributed to differences in protein stability, subcellular distribution, and/or RNA binding and virion

73 Changes in AQP4 subcellular distribution are associated with several neu

74 The protein shows a highly dynamic subcellular distribution between cytoplasm and flagellar

75 the tRNA reexport process and show that its subcellular distribution between the nucleus and cytopla

76 AR S-nitrosylation does not impact its subcellular distribution but attenuates its ability to b

77 nite-induced stress granules and changed the subcellular distribution, but not the abundance or integ

78 Our findings show that EGFR subcellular distribution can modulate DNA repair kinetic

79 However, USP18-sf shows different subcellular distribution compared with the full-length p

80 e divided into four classes reflecting their subcellular distribution (cytosol, nucleus, mitochondrio

81 However, automated quantification of MR subcellular distribution demonstrated that finerenone de

82 However, their subcellular distributions differed, as only CEL-MUT was

83 The importance of the subcellular distribution for the signaling activity of K

84 These data reveal a novel subcellular distribution for ZNF804A within somatodendri

85 under conditions of cell stress changes its subcellular distribution from peroxisomes to the nucleus

86 fy tyrosine kinase substrates based on their subcellular distribution from within cells.

87 ts expression relative to other calpains and subcellular distribution has not been investigated previ

88 nt protein and systematically surveyed their subcellular distribution, identifying enzymes specific t

89 The DEK1 polar subcellular distribution in 3D tissue developing cells d

90 n vitro and in situ, PIST displayed a patchy subcellular distribution in an area surrounding the nucl

91 However, their subcellular distribution in AVP or OC neurons of the PVN

92 anscriptional activity, without altering its subcellular distribution in hepatocytes.

93 That IIA and IIB assume distinct subcellular distribution in migrating cells suggests tha

94 ng the factors regulating muscle LIM protein subcellular distribution in myocytes.

95 ons, although GIRK2c achieved a more uniform subcellular distribution in pyramidal neurons and suppor

96 creased synthesis of AMPAR subunits on their subcellular distribution in rat hippocampal neurons.

97 The GRK5 subcellular distribution in the human striatal neurons i

98 first electron microscopy (EM) study of S1R subcellular distribution in the mouse retina.

99 channel activity, and pendrin abundance and subcellular distribution in wild-type and intercalated c

100 nse, we measured pendrin label intensity and subcellular distribution in wild-type mice, knockout mic

101 sion, DCT post-translational processing, and subcellular distribution is cell phenotype-dependent.

102 Their subcellular distribution is largely unknown.

103 In myocytes, muscle LIM protein subcellular distribution is regulated by cell contractil

104 gest that the Abeta-induced change in CaMKII subcellular distribution may underlie the removal of AMP

105 e absorption, distribution, cellular uptake, subcellular distribution, molecular mechanisms of action

106 The subcellular distribution of (64)Cu was measured by cell

107 determine the tissue-specific expression and subcellular distribution of 5862 mRNAs during Drosophila

108 Dissecting the subcellular distribution of a fatty-acylated protein is

109 ive single-molecule localization reveals the subcellular distribution of a monoamine transporter prot

110 icant changes in the expression level or the subcellular distribution of ABCB1 and ABCG2 in the cells

111 Furthermore, changes in subcellular distribution of active focal adhesion kinase

112 Moreover, Cdh6 knockdown alters the subcellular distribution of active Rho, which is known t

113 ealed stiffness-dependent differences in the subcellular distribution of actomyosin contractility, wi

114 ovide the first convincing evidence that the subcellular distribution of Ago2 occurs in a cell type-

115 emistry to study the regional, cellular, and subcellular distribution of AIDA-1.

116 al neuron subtypes that express AKAP150, the subcellular distribution of AKAP150, and the potential t

117 d that ATXN1 interacts with and controls the subcellular distribution of Alt-ATXN1.

118 The subunit composition and subcellular distribution of AMPARs and NMDARs are theref

119 oblasts and that HIPK4 deficiency alters the subcellular distribution of an F-actin capping protein i

120 The subcellular distribution of AnxA3 in the cellular endocy

121 High expression or aberrant subcellular distribution of Ape1 has been detected in ma

122 Surprisingly, the subcellular distribution of AQP4 clusters was different

123 We have characterized the expression and subcellular distribution of Arabidopsis thaliana ARP5 an

124 Dact1/2 regulate the subcellular distribution of beta-catenin, preventing bet

125 Western blot analysis were used to determine subcellular distribution of beta-catenin.

126 Accordingly, mechanisms triggering the subcellular distribution of both enzymes have been unexp

127 Finally, an analysis of the subcellular distribution of C5aR and C5L2 indicates that

128 evel of post-translational modifications and subcellular distribution of CacyBP/SIP change after acti

129 Subcellular distribution of calmodulin (CaM) in human im

130 Subcellular distribution of Calmodulin (CaM) in human im

131 patterns are determined by variations in the subcellular distribution of calmodulin (CaM), indicating

132 Recent insights into the subcellular distribution of cardiac and neuronal NaV iso

133 y, mtv1 nev/agd5 double mutants show altered subcellular distribution of CCV cargo exported from the

134 ysis revealed IR-induced phosphorylation and subcellular distribution of Chk2 phosphorylated species.

135 We further examined the subcellular distribution of CHT and observed that immuno

136 This pattern is consistent with the subcellular distribution of CHT displayed in other choli

137 echanism through which the expression and/or subcellular distribution of CK2 beta-subunits could part

138 we used Arabidopsis thaliana to examine the subcellular distribution of CL and CARDIOLIPIN SYNTHASE

139 form poised to provide new insights into the subcellular distribution of common H2S donors and a usef

140 ement of channels within a plaque determines subcellular distribution of connexin binding partners an

141 nuclear Ca(2+) signaling, we manipulated the subcellular distribution of CSQ2 by overexpression of CS

142 Subcellular distribution of CTCF and colocalization with

143 However, the subcellular distribution of CTLA-4 is unusual for a rece

144 ing new link to genetic variations affecting subcellular distribution of CYP2E1 with alcohol-induced

145 mRNA partitioning, we report an overlapping subcellular distribution of cytosolic/nucleoplasmic and

146 ion, and, in turn, altered expression and/or subcellular distribution of D2R in the PL.

147 V genotype in d3 lipid accumulation, and the subcellular distribution of d3.

148 Despite this differential subcellular distribution of DFF40/CAD, we find no differ

149 Arp2/3 affects the subcellular distribution of DLG-1 and ERM-1.

150 Instead, Ack is required for the subcellular distribution of Dock (dreadlocks), the Droso

151 R and to determine how agonists regulate the subcellular distribution of DOR.

152 By evaluating the subcellular distribution of each SecA, SecA1 was shown t

153 In the present work, we show that subcellular distribution of eIF6 in the nuclei and the c

154 In L924P there was also altered subcellular distribution of endogenous alpha1 subunit, a

155 ents' primary fibroblasts exhibited abnormal subcellular distribution of endosomes marked by Rab5, Ra

156 rhythmogenic, it is unknown whether distinct subcellular distribution of Epac1 vs. Epac2 contributes

157 ration over the wounded area by altering the subcellular distribution of F-actin.

158 on acts as a molecular switch to control the subcellular distribution of Fam13a.

159 We also obtained the subcellular distribution of fast and slow diffusing tRNA

160 Although glucose did not affect the subcellular distribution of FRQ in the WT, highly elevat

161 Here, we characterized the subcellular distribution of GABA(A)R subtypes in nocicep

162 onate pathway inhibitors, statins, influence subcellular distribution of Gbetagamma dimer and Galphab

163 e demonstrate that the expression levels and subcellular distribution of giant obscurins are altered

164 that, in the absence of VAMP8, the relative subcellular distribution of GLUT4 is altered, resulting

165 ith O-glycosylation of GNAT1 and affects the subcellular distribution of GNAT1.

166 lls to osmotic stress induces changes in the subcellular distribution of Gpd1p to the cytosol and nuc

167 However, cellular expression and subcellular distribution of GRKs and arrestins in the br

168 The subcellular distribution of HCN channels is regulated by

169 These data demonstrate that the regional and subcellular distribution of HDAC4 is heterogeneous and r

170 The subcellular distribution of hippocampal CB1 receptors of

171 In this study, we found that the subcellular distribution of Hsp82 is regulated by its co

172 ic colocalization of Rab GTPases defined the subcellular distribution of Hyal1 as early and late endo

173 We determined the subcellular distribution of individual machines, the sto

174 It thus regulates the abundance and subcellular distribution of its cargo within cells.

175 nt modes of interaction, and thus affect the subcellular distribution of K-Ras4B in different ways.

176 s in midtransmigration, we could monitor the subcellular distribution of L-selectin and better unders

177 The broad subcellular distribution of LEA proteins highlights the

178 te Saccharomyces cerevisiae We find that the subcellular distribution of LH is heterogeneous; the cyt

179 Manipulation of the subcellular distribution of LIP1 revealed that the circa

180 The subcellular distribution of lipids in human hair was inv

181 We therefore comprehensively determined the subcellular distribution of mammalian PATs in dorsal roo

182 defects were associated with changes in the subcellular distribution of markers of epithelial cell p

183 Previous reports have suggested that the subcellular distribution of Merlin is critical to its fu

184 The subcellular distribution of Met was characterized using

185 These results provide insight into the subcellular distribution of metabolic activities in the

186 They also highlight the fact that the subcellular distribution of mHTT is highly dynamic such

187 A activity and turnover can be controlled by subcellular distribution of miRNPs that may get differen

188 we propose a dynamic model that explains the subcellular distribution of misfolded proteins as a func

189 ations of mitochondrial dynamics altered the subcellular distribution of mitochondria in breast cance

190 ity, and directional migration, resulting in subcellular distribution of mitochondria to the peripher

191 insulin sensitivity are driven by changes in subcellular distribution of MKP7 and activated JNK.

192 nsider the spatial distribution of PTMs, the subcellular distribution of modifying enzymes, and their

193 GRK5 regulated the subcellular distribution of moesin and colocalized with

194 We previously reported that the subcellular distribution of Na(+),K(+)-ATPase is modulat

195 groove of this PDZ domain and determine the subcellular distribution of neuronal NOS (nNOS).

196 protein controls biophysical properties and subcellular distribution of neuronal voltage-gated Na(+)

197 PY(GFP) transgenic mice, we have studied the subcellular distribution of neuropeptide Y (NPY), a prot

198 in the levels, subunit composition, or gross subcellular distribution of NMDARs.

199 NS5A inhibitors had no overall effect on the subcellular distribution of NS5A, but completely prevent

200 ication phenotype correlated with an altered subcellular distribution of NS5A.

201 A replication, and its disruption alters the subcellular distribution of NS5A.

202 In contrast to alterations in the subcellular distribution of nuclear factors observed dur

203 The subcellular distribution of p63RhoGEF(580) and p63RhoGEF

204 re, we report a novel method for imaging the subcellular distribution of palmitoylated forms of cellu

205 We therefore investigated the subcellular distribution of Panx1 in the mouse retina of

206 re nuclear proteins are degraded because the subcellular distribution of peptidase activity has not b

207 ine the mechanism by which Akt3 controls the subcellular distribution of PGC-1alpha and to explore th

208 ut that a striking variability exists in the subcellular distribution of phosphorylated receptors amo

209 sed several orthogonal approaches to map the subcellular distribution of PI, including localizing exo

210 by the distinctive substrate specificity and subcellular distribution of PKDs.

211 nohistochemistry to analyze the cellular and subcellular distribution of PMCA1a in the brain.

212 s Nrf2 activity by controlling abundance and subcellular distribution of PML and that PML is essentia

213 aimed to identify changes in expression and subcellular distribution of proteins involved in IMTG st

214 Knowledge of the subcellular distribution of proteins is vital for unders

215 In agreement, the subcellular distribution of Rad23 is noticeably altered

216 cent microscopy (IFM) showed a change in the subcellular distribution of RHA from the nucleus to the

217 y of the hairpin region is important for the subcellular distribution of RHD3, and that reduced avail

218 t a second role of Y RNAs is to regulate the subcellular distribution of Ro.

219 cular transport are critical for an adequate subcellular distribution of S-acylated Ras proteins.

220 valuable tool to experimentally modulate the subcellular distribution of seed storage proteins.

221 ayed to ATP7A, we examined the abundance and subcellular distribution of several soluble COX assembly

222 demonstrated both reduced levels and altered subcellular distribution of STREX-containing BKCa channe

223 The subcellular distribution of synapses is fundamentally im

224 report that dap160 overexpression alters the subcellular distribution of synaptojanin, and overexpres

225 In cells lacking steryl esters, the subcellular distribution of Tgl4p and Tgl5p is unaffecte

226 Ialpha depletions altered the content and/or subcellular distribution of the BLOC-1-sensitive cargoes

227 r basis of this process, we investigated the subcellular distribution of the cathepsin B precursor, p

228 i responses to flow but markedly shifted the subcellular distribution of the channel toward the apica

229 Hence, perturbing the subcellular distribution of the chelator nicotianamine h

230 The subcellular distribution of the ClC-5:S244L variant was

231 e residues within the NES disrupt the normal subcellular distribution of the full-length CIITA, impai

232 The subcellular distribution of the G protein-coupled recept

233 s fused to localization domains to alter the subcellular distribution of the GFP-tagged mRNA or prote

234 DNA into patient's fibroblasts corrected the subcellular distribution of the lysosomes, supporting th

235 these mice left open questions regarding the subcellular distribution of the mutant protein and the n

236 The subcellular distribution of the oligonucleotide delivere

237 microscopy was used to determine whether the subcellular distribution of the organizer/adapter NOX p4

238 We found that subcellular distribution of the p57kip2 protein changed

239 methionine at position 148 did not alter the subcellular distribution of the protein.

240 of IRES activation, although the levels and subcellular distribution of the proteins were unchanged.

241 Both cellular uptake and subcellular distribution of the PSs were affected by the

242 Using these methods, we investigated the subcellular distribution of the receptors GluClalpha, Rd

243 In NPCs, Pml regulated the subcellular distribution of the retinoblastoma protein (

244 ed between eIF2alpha phosphorylation and the subcellular distribution of the RNA-binding protein hete

245 hus, findings suggest that selection for the subcellular distribution of the SEN complex may reside n

246 the selectivity of drug actions based on the subcellular distribution of their targets.

247 adipocytes, but differentially regulates the subcellular distribution of these Akt isoforms.

248 An altered subcellular distribution of these ligands is found in mu

249 ts have uncovered a relationship between the subcellular distribution of these metalloinsertors and t

250 Here we discuss the nature and subcellular distribution of these posttranslational mark

251 We discovered a strictly segregated subcellular distribution of these proteins and a sequent

252 ovessels of S1pr1(iECKO) mice showed altered subcellular distribution of tight junctional proteins.

253 omer-Golgi plasmids and used to identify the subcellular distribution of TLR4 before and after LPS st

254 Of particular interest, the subcellular distribution of TP-modified ODNs is highly d

255 The subcellular distribution of transcripts differed in thei

256 n-regulation of either exporter affected the subcellular distribution of tRNAs.

257 ainst TRPML3 to determine the expression and subcellular distribution of TRPML3 in the inner ear as w

258 Ca(2+) signaling as well as the function and subcellular distribution of TRPV4.

259 +)]i responses to flow without affecting the subcellular distribution of TRPV4.

260 copy and transgenesis were used to study the subcellular distribution of xlProminin-1.

261 ation signal, and although we found that the subcellular distribution of Xrcc3 was not significantly

262 In this study, the cellular and subcellular distributions of As and silicon (Si) in rice

263 However, the subcellular distributions of DLG1 and LIN7C are independ

264 and is often not adequate to explore in situ subcellular distributions of elements and proteins in bi

265 m IL-33-producing cells or by differences in subcellular distributions of IL-33 isoforms.

266 Glucose availability regulates the subcellular distributions of karyopherins likely due to

267 Subcellular distributions of Msn5 and Los1 are altered u

268 indings illuminate the relationships between subcellular distributions of RNA and protein in developi

269 s, with particular relevance for probing the subcellular distributions of small molecules, such as dr

270 optimized for detection of the cellular and subcellular distributions of specific mRNA within Drosop

271 functions directly result from the distinct subcellular distributions of the two Rnd proteins.

272 The cellular and subcellular distributions of trace elements can provide

273 oping axons, yet little is known about their subcellular distribution or, specifically, which transcr

274 The properties and subcellular distribution pattern of HCN channels are the

275 The subcellular distribution pattern of the HCN channels inf

276 in DLBCLs resulting from differences in the subcellular distribution pattern.

277 t, side-view shear strains exhibited similar subcellular distribution patterns in both networks.

278 These subcellular distribution patterns were recapitulated in

279 differentially expressed and have different subcellular distribution patterns.

280 Based on the biochemical and subcellular distribution properties of U1-70K in AD, we

281 cally active new Kdm3a isoform and show that subcellular distribution, protein levels, and lysine dem

282 the actin cytoskeleton, markedly alters Gag subcellular distribution, relocates sites of assembly, a

283 This was accompanied by changes in PP2A subcellular distribution resulting in increased physical

284 Subsequent determination of silver subcellular distribution revealed that significantly mor

285 sponse to anaerobiosis by regulating RNase E subcellular distribution, RNase E enzymatic activity, an

286 ing their study, lncRNAs have widely varying subcellular distributions: some reside predominantly in

287 tes provide singular information about H-Ras subcellular distribution that is required for GTPase sig

288 Subcellular distribution, tissue-specific expression, su

289 clusters within the data, suggesting similar subcellular distributions to one another, as expected fo

290 us effect on the growth-supporting activity, subcellular distribution, tRNA binding, or interactions

291 nd that all tested karyopherins invert their subcellular distributions upon glucose deprivation but n

292 GABAAR complexes that explain GABAAR subunit subcellular distributions using mice and Xenopus laevis

293 In general, the cortex structure and subcellular distribution vary significantly across cell

294 oteins that adopt distinct conformations and subcellular distributions when associated with different

295 Copines exhibit a variety of subcellular distributions when overexpressed in tissue c

296 mutants of H-Ras differed not only in their subcellular distribution, where both proteins localized

297 Proteins exhibit complex subcellular distributions, which may include localizing

298 ating that our methods can unmix the complex subcellular distribution with reasonably high accuracy.

299 ngly, the pUL136 isoforms exhibited distinct subcellular distributions with varying association with

300 ctional proteins translates to heterogeneous subcellular distribution within a cardiac myocyte.